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Study on the therapeutic effect of Spironolactone and Torasemide in patients with chronic pulmonary heart disease |
ZENG Xing-du WU Guo-bin |
Department of Respiratory Medicine,the First Affiliated Hospital of Gannan Medical College,Jiangxi Province,Ganzhou 341000,China |
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Abstract ObjectiveTo investigate the clinical effect of Spironolactone and Torasemide in patients with chronic pulmonary heart disease.MethodsA total of 72 patients with chronic pulmonary heart disease who treated in our hospital from June 2015 to December 2016 were selected as objects and were randomly divided into control group and observation group according to the random number table method.There were 36 patients in each group.The control group was treated with Tonic and Diuretic and other conventional methods.The observation group was treated with Spironolactone and Torasemide on the basis of the control group.The clinical curative effect and cardiac function were compared between the two groups.ResultsThe total effective rate in the observation group was 97.22%and 83.33%in the control group,the difference was statistically significant(P<0.05).Before treatment and after treatment,the cardiac function grading of the two groups was compared,the differences were not statistically significant(P>0.05).After treatment,the patients ofⅡ level in the control group was more than before treatment,the patients ofⅣ level was less than before treatment,the difference was statistically significant(P<0.05).After treatment,the patients ofⅡ level in the observation group was more than before treatment,the patients ofⅢandⅣlevel were less than before treatment,the difference was statistically significant (P<0.05).ConclusionThe treatment of patients with chronic pulmonary heart disease by using Spironolactone and Tolosemide on the basis of the use of Tonic and Diuretics can effectively improve the patients′cardiac function,reduce the grade of cardiac function and improve the therapeutic effect.
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