氯吡格雷联合川芎嗪注射液治疗急性脑梗死的临床疗效及对血液流变学的影响

Abstract
Figure/Table
References (15)
Related Citation (14)

Download: PDF (0 KB) HTML (31 KB)
Export: BibTeX | EndNote (RIS)

Abstract ObjectiveTo investigate the clinical effects of Clopidogrel combined with Ligustrazine Injection in the treatment of acute cerebral infarction and its influence on hemorheology.Methods118 cases of patients with acute cerebral infarction who treated in our hospital from April 2014 to December 2016 were selected as the research objects,and were divided into the control group of 62 cases and the observation group of 56 cases according to the medication regimen.The control group were treated with Clopidogrel on the basis of conventional treatment,while the observation group were treated with Ligustrazine Injection on the basis of treatment in the control group.Then,the clinical efficacy and hemorheology of two groups of patients after the treatment were observed and compared.ResultsThe total effective rate in the observation group(91.07%)was higher than that in the control group(79.03%),and the difference was statistically significant(P＜0.05).Before the treatment,there was no significant difference in the hemorheological indexes between the two groups(P＞0.05).After the treatment,the hemorheological indexes of the two groups were lower than before treatment,the observation group was lower than the control group,the differences were statistically significant(P＜0.05).ConclusionThe Clopidogrel combined with Ligustrazine Injection which can improve the clinical efficacy of acute cerebral infarction,but also can improve the hemorheological indexes,thus it is worthy to be promoted in the clinical.

Key words： Ligustrazine injection Clopidogrel Acute cerebral infarction Hemorheology

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	ZHOU Ying-feng

Cite this article:

ZHOU Ying-feng. Clinical effect of Clopidogrel combined with Ligustrazine Injection in the treatment of acute cerebral infarction and its influence on hemorheology[J]. 中国当代医药, 2017, 24(30): 86-88.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I30/86

[1]	王丽萍，陈真，李梅，等.我国6省市脑卒中流行病学调查及危险因素分析[J].中国病案，2017，18（3）：97-100.
[2]	刘佳，闫建齐.急性脑梗死患者血浆内皮素及血液流变学指标检测分析[J].解放军预防医学杂志，2015，33（2）：187-188.
[3]	王朝阳，张茂林，鲁启洪，等.川芎嗪注射液对急性缺血性脑卒中患者血清MMP-9及神经功能缺损的影响[J].吉林中医药，2015，35（2）：133-135.
[4]	中华医学会神经病学分会脑血管病学组急性缺血性脑卒中诊治指南撰写组.中国急性缺血性脑卒中诊治指南2010[J].中华神经科杂志，2010，43（2）：146-153.
[5]	杜伟，庞长河，薛亚轲，等.美国神经重症监护学会《大面积脑梗死治疗指南（2015）》解读[J].中华神经医学杂志，2016，15（1）：2-5.
[6]	郭运芬.脑梗死患者血小板参数凝血功能和血液流变学指标检测的临床价值[J].山西医药杂志，2015，44（3）：257-259.
[7]	陆维君，郭晨龙.曲克芦丁脑蛋白水解物注射液联合丹参川芎嗪注射液对急性脑梗死患者神经功能及血液流变学的影响[J].实用心脑肺血管病杂志，2015，23（3）：59-61.
[8]	黎明丽，宋薇，刘薇芝，等.依达拉奉联合氯吡格雷对比单用氯吡格雷治疗急性脑梗死疗效与安全性的Meta分析[J].中国药房，2016，27（33）：4675-4678.
[9]	梁秋溪.疏血通注射液联合氯吡格雷治疗缺血性脑卒中的疗效及对患者神经功能与血液流变学的影响[J].检验医学与临床，2015，12（21）：3189-3191.
[10]	夏晓冬，沈巍，陈星，等.奥扎格雷钠联合川芎嗪注射液对急性脑梗死患者血清同型半胱氨酸、C反应蛋白及纤维蛋白原水平的影响[J].现代生物医学进展，2016，16（28）：5502-5504.
[11]	张玉淼，王红莲，周宏斌，等.丹参川芎嗪注射液对缺血性脑卒中患者血流变及外周血BCL-2、BAX、Caspase-3蛋白水平的影响[J].中药材，2015，38（9）：2003-2005.
[12]	李震亮，姚冬梅，幺桂兰，等.丹参川芎嗪注射液联合低分子肝素治疗急性脑梗死的疗效观察[J].现代药物与临床，2016，31（8）：1184-1187.
[13]	陈赟.丹参川芎嗪注射液联合西药对急性脑梗死患者血液流变学及血浆TXB2、6-Keto-PGF1α含量的影响[J].中国中医急症，2017，26（1）：181-183.
[14]	蓝宇，肖建新，郑天勇，等.丹参川芎嗪注射液治疗急性脑梗死的疗效及对溶血磷脂酸、P选择素的影响[J].现代中西医结合杂志，2015，24（8）：840-842.
[15]	孙红国，于福恩，万明花，等.川芎嗪对脑梗死患者血流变及血小板指标的影响[J].海南医学院学报，2015，21（5）：709-711，714.