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2019 Vol. 26, No. 7
Published: 2019-03-08
4
Influence of Guanxin Danshen Dropping Pills on the curative effect and nitric oxide and interleukin-6 in patients with unstable angina pectoris
WANG Shi-kai1SUN Ping1LI Ming-sheng1ZHANG Lei1LIANG Jiang-jiu2▲
Objective
To observe the influence of Guanxin Danshen Dropping Pills on the curative effect and nitric oxide and interleukin-6 content in patients with unstable angina pectoris.
Methods
All of 217 patients treated in the First People′s Hospital of Ningyang County from January 2014 to January 2017 were selected as the study subjects.They were divided into the treatment group(122 cases)and control group(95 cases)according to the random grouping method.The treatment group was treated with basic treatment and Guanxin Danshen Dropping Pills,while the control group was treated with basic treatment.The changes of the seattle angina scale(SAQ),the Canadian cardiovascular society score (CCS),and the levels of NO and IL-6 were compared before and after treatment between the two groups.
Results
Before treatment,there was no significant difference in SAQ score in patients between the two groups(
P
>0.05).After 14,21 and 28 days of treatment,the SAQ scores of the two groups were higher than those before treatment,with significant differences(
P
<0.05);after 14,21 and 28 days of treatment,the SAQ score of the treatment group were higher than those of the control group,with significant differences(
P
<0.05).There was no significant difference in the CCS score in patients between the two groups before treatment(
P
>0.05);the CCS scores of the two groups after 14,21 and 28 days of treatment were lower than those before treatment,with significant differences(
P
<0.05);the CCS score of the treatment group after 14,21 and 28 days of treatment was lower than that of the control group,with significant differences (
P
<0.05).The NO content in the treatment group was higher than that in the control group after 21,28 days of treatment,with significant differences (
P
<0.05),and the IL-6 content in the treatment group was lower than that in the control group after 14,21 and 28 days of treatment,with significant differences(P<0.05).There was a positive correlation between NO content and SAQ score(r=0.68,P=0.01),and a negative correlation between IL-6 content and SAQ score(r=-0.55,P=0.02).
Conclusion
Guanxin Danshen Dropping Pills can improve the curative effect of angina pectoris and the quality of life.Its mechanism may be related to improving endothelial function and reducing the content of IL-6.
2019 Vol. 26 (7): 4-7 [
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85
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8
Summary evaluation of Meta-analysis for prevention of postoperative complications after parotid gland tumor resection
LI Xiao-bao1WU Lan1WANG Yue-chun1▲ ZHAO De-lu1ZHU You-jia1WANG Cui-xia2
Objective
To systematically evaluate the meta-analysis for prevention of postoperative complications after parotid gland tumor resection.
Methods
Meta-analysis of for prevention of postoperative complications after parotid gland tumor resection was retrieved from PubMed,Cochrane Library,CNKI and WanFang Data.The search time was from building database to September 12,2018.According to the inclusion criteria,literature was screened and data were extracted.The quality of inclusion study was evaluated by AMSTAR scale.
Results
A total of 24 studies were included to investigate the effects of 13 interventions on the prevention of complications after parotid gland tumor resection.The AMSTAR quality evaluation Results showed 3 studies were high quality,16 studies were moderate quality,and 5 studies were low quality.
Conclusion
The interventions involved in this study have certain effects on the prevention of Frey syndrome,salivary fistula/effusion,and facial deformity.There is no obvious effect on postoperative recurrence or infection,and the effect on facial nerve palsy is uncertain.In addition,there is still a need for rigorous and standardized original research,direct comparative meta-analysis/systematic evaluation or indirect comparative mesh metaanalysis to provides more reliable and comprehensive evidence for clinic.
2019 Vol. 26 (7): 8-12 [
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101
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13
Influence of Propofol-Ketamine anesthesia on cytokine balance in early stage of severe burn in rabbits
[Abstract]
Objective
To investigate the influence of Propofol-Ketamine anesthesia on cytokine balance in early stage of severe burn in rabbits.
Methods
Thirty male New Zealand rabbits were selected and they were randomly divided into normal control group(group C,n=10),burn control group(group BC,n=10)and Propofol-Ketamine anesthesia group(group PK,n=10).The internal jugular vein and external carotid artery were placed in the tube after anesthesia with Sodium Pentobarbital a day before burn.On the day of the experiment,the rabbits in group BC and group PK were made into 30%body surface area (TBSA)3 degree burn models.In group PK,Propofol 1.5 mg/kg was injected intravenously 1 hours after injury,then endotracheal intubation 90 s later,next half closed oxygen supply with anesthesia machineopen,retaining spontaneous breathing,Propofol of 0.15 mg/(kg·min)and Ketamine of 0.15 mg/(kg·min)were infused intravenously to maintain anesthesia,and the drugs were discontinued after 4 hours of anesthesia.Group C was injected Sodium lactate Ringer solution,and the input volume was 80 ml/(d·kg).Group BC and PK were injected crystal colloid(1∶1),and the volume of fluid infusion was 1.75×(%TBSA)×weight+80 ml/(d·kg).Before burn and 1,6,12 and 24 hours after burn,arterial blood was collected for blood gas analysis,and serum levels of interleukin-1 (IL-1),interleukin-6(IL-6)and tumor necrosis factor-α (TNF-α)concentration were measured by venous blood sampling.
Results
There was no significant difference in the volume of transfusion between group BC and PK(P＞0.05).Compared with group C,the volume of transfusion in group BC and PK increased significantly,and the differences were statistically significant(P＜0.05).PaCO
2
in group BC and PK after burn was significantly lower than that in group C(P＜0.05).Lac in group BC and PK after burn was significantly higher than that before burn (P＜0.05),and group PK was significantly lower than that group BC (P＜0.05).There was no significant difference in pH,PaO
2
and SaO
2
at any time points compared with that before burn (P＞0.05).IL-1,IL-6 and TNF-α in group BC and PK after burn were significantly higher than those before burn (P＜0.05).Group PK anaesthetized by Propofol-Ketamine,the concentration of IL-1,IL-6 and TNF-α in group PK were lower than those in group BC at 6,12 and 24 h after burn (P＜0.05).
Conclusion
Propofol-Ketamine anesthesia can effectively reduce the level of serum cytokines,inhibit systemic inflammatory response in the early stage of severe burn,at the same time,it can improve tissue perfusion,which is conducive to early recovery of severe burn.
2019 Vol. 26 (7): 13-16 [
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84
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17
Research progress on factors of influencing survival rate of primary thyroid squamous cell carcinoma
LIN Shi-ang ZHANG Yue-feiLUO Guo-qing HE Ruo-yun
[Abstract]
Primary squamous cell carcinoma of the thyroid gland is a rare disease,there is currently no corresponding standard treatment plan for it.The survival rate of patients with primary thyroid squamous cell carcinoma is not same and not satisfactory.Factors affecting the survival rate of patients with primary thyroid squamous cell carcinoma have become the focus studied by more and more scholars in recent years.This article summarizes the findings of important literature in this field in recent years,and explores the influencing factors of survival rate in patients with primary thyroid squamous cell carcinoma.
2019 Vol. 26 (7): 17-20 [
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76
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24
Study progress in clinical treatment of maintenance hemodialysis patients with hyperuricemia
PENG Ting LIU Ling▲
[Abstract]
Renal insufficiency is a risk factor for hyperuricemia,and studies have shown that hyperuricemia is prone to endothelial dysfunction.For patients with maintenance hemodialysis with hyperuricemia,because of the side effects of drugs and the inaccurate treatment effect,there is no standardized clinical treatment standard,which leads to different clinical treatment options.This study reviewed the clinical treatment of patients with maintenance hemodialysis combined with hyperuricemia,and provided recommendations for further guidance on related treatments.
2019 Vol. 26 (7): 24-28 [
Abstract
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90
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25
Research progress of different coronary artery bypass grafting technology in the treatment of coronary heart disease
CHEN Bai-lang1LI Han1WEI Min-xin2▲
[Abstract]
Coronary artery bypass grafting (CABG)is the main treatment programme for multiple vessel lesions of coronary atherosclerosis.With the development in recent decades,great progress has been made in bypass technology from the initial cardiopulmonary bypass,the later non-cardiopulmonary bypass,to minimally invasive small incision and robot-assisted bypass.Minimally invasive surgery has been paid more and more attention because it reduces trauma and recovery time.In order to increase the patency rate of vascular graft,external stent and “on touch” technology have been developed.Moreover,hybrid surgery has combined the advantages of bypass and percutaneous coronary intervention(PCI)to better benefit patients.In addition,adjuvant molecular therapy can provide alternative microvascular revascularization for patients who are not suitable for traditional coronary artery revascularization.This paper summarizes the new progress of bypass technology in recent years.
2019 Vol. 26 (7): 25-28 [
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98
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29
Application effect of Inflammation-Resolving Gall-Bladder-Excreting Tablets combined with percutaneous transhepatic cholangioscopy lithotripsy in the treatment of cholelithiasis
JIANG Zhi-yuan WANG San-guiGAO Lian-xiang LIU Zhi-ping LI Xiao-qing
[Abstract]
Objective
To explore the effect of Inflammation-Resolving Gall-Bladder-Excreting Tablets combined with percutaneous transhepatic cholangioscopy lithotripsy in the treatment of cholelithiasis.
Methods
Eighty patients with cholelithiasis admitted to our hospital from April 2017 to April 2018 were selected as the research objects,according to the random number table method,they were divided into observation group and control group,with 40 cases in each group.The control group received only percutaneous transhepatic cholangioscopy lithotripsy,while the observation group received Inflammation-Resolving Gall-Bladder-Excreting Tablets plus percutaneous transhepatic cholangioscopy lithotripsy.The incidence of complications and recurrence rate of stones were compared between the two groups,and the scores of TCM symptoms before and 6 months after operation were evaluated and compared.
Results
The total incidence of complications after operation in the observation group was 7.50%,which was significantly lower than 27.50%in the control group,the difference was significant(P<0.05).There was no recurrence in the observation group after operation,which was significantly lower than 10.00%in the control group,the difference was significant(P<0.05).The scores of TCM symptoms at 6 months after operation in the observation group were significantly lower than those in the control group,the difference was significant(P<0.05).
Conclusion
In the treatment of patients with cholelithiasis,Inflammation-Resolving Gall-Bladder-Excreting Tablets combined with percutaneous transhepatic cholangioscopy lithotripsy for the treatment of cholelithiasis has achieved remarkable Results in improving the scores of TCM symptoms of patients and reducing the recurrence rate of stones,which is worthy of popularization and application.
2019 Vol. 26 (7): 29-31 [
Abstract
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86
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32
Value of three-dimensional ultrasound in diagnosis of female pelvic floor dysfunction
LUO Ying-de
[Abstract]
Objective
To explore the value of three-dimensional ultrasound in the diagnosis of female pelvic floor dysfunction disease (PFD).
Methods
A total of 76 patients with pelvic floor dysfunction admitted to our hospital from December 2016 to December 2017 were selected as the study group,and 60 normal women who underwent physical examination in the same period were selected as the reference group,two-dimensional and three-dimensional perineal ultrasound were used to detect and diagnose PFD,the diagnostic efficacy of two-dimensional and three-dimensional perineal ultrasound was compared.Three-dimensional ultrasonography was used to compare the changes of anteroposterior diameter,area and levator ani muscle thickness of the pelvic and phrenic hiatus in the two groups at different stages.
Results
The sensitivity,specificity and diagnostic coincidence rate of three-dimensional ultrasound for PFD were 89.47%,95.00%and 91.91%respectively,which were higher than those of two-dimensional ultrasound for PFD(69.74%,80.00%,74.26%),the differences were significant(P<0.05).The anteroposterior diameter and area of pelvic and phrenic hiatus before and after treatment in the study group were significantly larger than those in the control group (P<0.05).There was no significant difference in Puborectalis muscle thickness between the study groups before treatment and reference group(P>0.05).After treatment,the anteroposterior diameter and area of the pelvic and phrenic hiatus in the study group were smaller than those before treatment in different periods,the differences were statistically significant(P<0.05).After treatment,there was no significant difference in Puborectalis muscle thickness between before and after treatment(P>0.05).
Conclusion
Transperineal three-dimensional ultrasound can clearly show the changes of pelvic floor anatomy and pelvic floor function,improve the accuracy of PFD diagnosis,and provide information about the diameter and area of pelvic diaphragm fissure.It has important application value in clinical diagnosis,treatment and rehabilitation evaluation.
2019 Vol. 26 (7): 32-34转38 [
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97
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35
Study on the correlation between erythrocyte distribution width and cardiocerebrovascular events in patients with hemodialysis
JIANG Xin-ai*REN Shan*LI Peng▲
[Abstract]
Objective
To explore the correlation between erythrocyte distribution width and cardiocerebrovascular events in patients with hemodialysis.
Methods
A total of 300 hemodialysis patients treated in the Second People′s Hospital of Jingdezhen City from May 2015 to December 2016 were selected as the research objects,according to the distribution width of erythrocyte,they were divided into normal group(187 cases)and abnormal group(113 cases),the incidence of cardiocerebrovascular events was compared between the two groups.According to the cardiocerebrovascular events,the patients were divided into two groups:the onset group(107 cases)and the non-onset group(193 cases),the distribution width of erythrocyte was compared between the two groups.Multiple factor Logistic regression was used to analyze the influencing factors of cardiocerebrovascular events in hemodialysis patients.The correlation between erythrocyte distribution width and cardiocerebrovascular events in hemodialysis patients was analyzed.
Results
The incidence of cardiocerebrovascular events in abnormal group was higher than that in normal group(P<0.05).The dialysis age of the patients was longer than that of the non-patients(P<0.05).The distribution width of erythrocyte,high sensitivity C-reactive protein and ferritin in the patients were higher than those in the non-patients(P<0.05).Hemoglobin,albumin,serum creatinine,urea nitrogen,uric acid and N-terminal brain natriuretic peptide precursors were lower in the onset group patients than in the non-patients (P<0.05).Dialysis age,erythrocyte distribution width,hemoglobin,albumin,serum creatinine,urea nitrogen,uric acid,N-terminal brain natriuretic peptide precursor,high-sensitivity C-reactive protein and ferritin are all influencing factors of cardiovascular and cerebrovascular events in hemodialysis patients.The distribution width of erythrocyte was positively correlated with cardiovascular and cerebrovascular events in hemodialysis patients(r=0.439,P<0.05).
Conclusion
Erythrocyte distribution width is an independent risk factor for cardiovascular and cerebrovascular events in hemodialysis patients,and there is a significant positive correlation between them.
2019 Vol. 26 (7): 35-38 [
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90
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39
Selection of surgical timing for strangulated intestinal obstruction and its impact on prognosis
XUE Yi-hua
[Abstract]
Objective
To investigate the selection of surgical timing for strangulated intestinal obstruction and its impact on prognosis of the disease.
Methods
Clinical data of 104 patients with strangulated intestinal obstruction admitted to our hospital from January 2014 to July 2018 were retrospectively analyzed,according to the time from admission to operation,patients were divided into early operation group(61 cases)and late operation group(43 cases).The early operation group received surgery within 12 hours of admission,while the late operation group received surgery for more than 12 hours.The operation mode,prognosis,total effective rate and recovery were compared between the two groups.
Results
There was no significant difference in the proportion of different surgical metheds between the two groups(P>0.05).The rate of intestinal necrosis and mortality in early operation group were significantly lower than those in late operation group(P<0.05).The total effective rate of early operation group was significantly higher than that of late operation group (P<0.05).The time of anal exhaust,eating and getting out of bed in the early operation group were significantly shorter than those in the late operation group(P<0.05).
Conclusion
In the selection of operation time for strangulated intestinal obstruction,indications for operation can be expanded and the operation time should be advanced.The operational intervention should be given before intestinal necrosis as far as possible,which can help to improve the operation effect,save the lives of patients and improve the clinical prognosis.
2019 Vol. 26 (7): 39-41 [
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89
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42
Application effect of laryngeal recurrent nerve monitor in complicated thyroid surgery
WANG LingZHOU Yan CUI Ling
[Abstract]
Objective
To explore the application effect of recurrent laryngeal nerve monitor in complicated thyroid surgery.
Methods
A retrospective analysis was made of 102 cases of complicated thyroid surgery case information in our hospital from January 2014 to February 2018,according to whether or not the recurrent laryngeal nerve monitor was used to expose the recurrent laryngeal nerve during operation,the patients were divided into intraoperative nerve monitoring(IONM)group(48 cases)and non-IONM group(54 cases),the injury rate was calculated according to the number of recurrent laryngeal nerves involved in the operation,the rate of recurrent laryngeal nerve injury,operation time,exposure time of recurrent laryngeal nerve,amount of bleeding during operation,total cost of hospitalization and anesthesia time were compared between the two groups.
Results
After intervention with recurrent laryngeal nerve(RLN)monitor,the rate of temporary RLN injury in IONM group was lower than that in non-IONM group,the difference was significant(P<0.05).There was no recurrent laryngeal nerve injury in both group.The operation time and exposure time of RLN in IONM group were shorter than that in non-IONM group,the amount of bleeding during operation was less than that in non-IONM group,and the hospitalization cost was higher than that in non-IONM group,the difference was statistically significant(P<0.05).There was no significant difference in anesthesia time between the two groups(P>0.05).
Conclusion
Recurrent laryngeal nerve monitor can reduce the rate of temporary recurrent laryngeal nerve injury in complicated thyroid surgery,especially in reoperation,it can effectively shorten the operation time,the exposure time of recurrent laryngeal nerve and reduce the amount of bleeding.It is worth popularizing.
2019 Vol. 26 (7): 42-44转48 [
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97
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45
Application effect of bronchoscopic lung lavage in patients with mechanical ventilation combined with pulmonary infection
ZHANG Yan SU Xiao-leiZHAO RuiZHU HongFANG Kai-yu
[Abstract]
Objective
To expolre the application effect of bronchoscopic lung lavage in patients with mechanical ventilation combined with pulmonary infection.
Methods
A total of 92 patients with mechanical ventilation combined with pulmonary infection in our hospital from June 2017 to June 2018 were selected as the study subjects,they were divided into control group (46 cases)and observation group (46 cases)according to random number table method,the control group received routine treatment,while the observation group received routine treatment combined with bronchofibrous lung lavage.After one week of treatment,the total effective rate,procalcitonin(PCT),white blood cell(WBC)count,C-reactive protein(CRP)and blood gas indexes of the two groups were observed and compared,blood gas indexes included blood oxygen saturation(SaO
2
),arterial partial pressure of oxygen(PaO
2
)and arterial partial pressure of carbon dioxide(PaCO
2
).
Results
The total effective rate of the observation group was higher than that of the control group,the difference was significant(P<0.05).The levels of CT,CRP and WBC in the two groups after treatment were lower than those before treatment,and those in the observation group were lower than in the control group,the differences were significant(P<0.05).After treatment,the levels of SaO
2
and PaO
2
in both groups were higher than those before treatment,and the levels of PaCO
2
were lower than those before treatment,after treatment,the levels of SaO
2
and PaO
2
in the observation group were higher than those in the control group,and the levels of PaCO
2
in the observation group were lower than those in the control group,the differences were significant(P<0.05).
Conclusion
Fiberoptic bronchoscope lung lavage therapy can promote sputum discharge,improve inflammatory and blood gas indicators in patients with mechanical ventilation combined with pulmonary infection,which is worthy of clinical application.
2019 Vol. 26 (7): 45-48 [
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49
Effect and safety observation of endoscopic retrograde cholangiopancreatography in the treatment of elderly patients with single choledocholithiasis
CHEN Wen-zhe
[Abstract]
Objective
To explore the effect and safety of endoscopic retrograde cholangiopancreatography (ERCP)in the treatment of elderly patients with single choledocholithiasis.
Methods
Sixty elderly patients with single choledocholithiasis admitted to our hospital from March 2013 to July 2017 were selected as the study subjects,they were divided into observation group and control group by random number table method,with 30 cases in each group.The observation group was treated with ERCP lithotripsy,while the control group was treated with Laparoscopic Choledocholithotomy.The general conditions of perioperative period(exhaust time,visual analogue scale[VAS]score,hospitalization time),stone removal effect(residual stone rate,recurrence rate of 6 months)were compared between the two groups,and the preoperative and postoperative 1W were evaluated.The levels of liver function(ALT,AST and GGT)were recorded and compared between the two groups.
Results
The exhaust time and hospitalization time in the observation group were shorter than those in the control group(P<0.05),postoperative VAS score was lower than that of control group(P<0.05).There was no significant difference in residual stone rate and recurrence rate of 6 months between the two groups(P>0.05).The levels of ALT,AST and GGT in the two groups were lower than those before operation at one week after operation (P<0.05),the levels of ALT,AST and GGT in the observation group one week after operation were lower than those in the control group (P<0.05).There was no significant difference in the total incidence of postoperative complications between the two groups(P>0.05).
Conclusion
ERCP lithotripsy is similar to laparoscopic choledocholithotomy in the treatment of single choledocholithiasis,but the former is more advantageous in improving perioperative conditions and promoting the recovery of liver function indicators.
2019 Vol. 26 (7): 49-51转64 [
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52
Effect of different decompression time of radial artery compressor on patients undergoing coronary intervention
LI Chun-ni1WU Yi-sha2YE Dong-hong3
[Abstract]
Objective
To explore the effect of different decompression time of radial artery compressor on patients undergoing coronary intervention.
Methods
A total of 160 patients with TR-Band hemostatic balloon who underwent coronary artery interventional therapy in our hospital from June 2017 to May 2018 were selected as the study subjects.They were divided into 2-hour group(n=50),4-hour group(n=55)and 6-hour group(n=55)according to the time of decompression after operation.The radial artery pulsation,local wound discomfort and complications were observed and compared among the three groups.
Results
There was no significant difference in the incidence of bleeding and hematoma at puncture site between the three groups (P>0.05).The incidence of swelling,numbness,cyanosis,wound pain,vagal reflex and radial artery occlusion in the 2-hour group were significantly lower than those in the 4-hour group and 6-hour group (P<0.05).The NRS score of 2-hour group was significantly lower than that of 4-hour group and 6-hour group (P<0.05).
Conclusion
It is feasible and safe to compress the puncture site with a hemostatic balloon for 2 hours after coronary artery interventional surgery.It has fewer complications and is worth adopting.
2019 Vol. 26 (7): 52-54 [
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92
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55
Clinical effect of Spironolactone combined with Carvedilol in the treatment of refractory hypertension
ZHANG Zhi-bin ZHONG MingHUANG Li-qun ZHU Heng-qing
[Abstract]
Objective
To investigate the clinical effect of Spironolactone combined with Carvedilol in the treatment of refractory hypertension.
Methods
A total of 80 patients with refractory hypertension admitted in our hospital from January 2017 to August 2018 were selected as the subjects,and randomly divided into routine group (n=40)and study group (n=40).Carvedilol was used in routine group.The study group was treated with Carvedilol combined with Spironolactone.The blood pressure,echocardiography and clinical efficacy were compared between the two groups.
Results
After treatment,the blood pressure of the two groups were significantly lower than those of the conventional group,and the blood pressure of the study group were significantly lower than that of the conventional group,with statistically significant differences(P<0.05).After treatment,the left ventricular ejection fraction of the two groups was higher than that before treatment,and the left ventricular ejection fraction of the study group was higher than that of the conventional group,with statistically significant differences(P<0.05).After treatment,the inner diameter at the end of left ventricular contraction was smaller than that before treatment in both groups,and the inner diameter at the end of left ventricular contraction in the study group was smaller than that of the conventional group,with statistically significant differences (P<0.05).The total effective rate of the study group was significantly higher than that of the conventional group (P<0.05).The total incidence of adverse reactions in the study group was lower than that in the conventional group,and the difference was statistically significant(P<0.05).
Conclusion
Spironolactone combined with Carvedilol is effective in the treatment of refractory hypertension.It can not only improve the blood pressure and echocardiographic parameters,but also reduce the incidence of adverse reactions.It is worth popularizing in this area.
2019 Vol. 26 (7): 55-57 [
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72
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58
Clinical effect of Amiodarone in the treatment of acute arrhythmia
LUO Yao-mingDEGN Yu-hua
[Abstract]
Objective
To explore the clinical effect of Amiodarone in the treatment of acute arrhythmia.
Methods
A total of 62 patients with acute arrhythmia admitted to our hospital from December 2016 to May 2018 were selected as the subjects,and divided into two groups by lottery,with 31 cases in each group.The control group was treated with basic treatment,and the observation group was treated with basic treatment and amiodarone treatment.The therapeutic effect,cardiac function index and therapeutic safety of two groups were compared.
Results
The total treatment effect in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).The left ventricular ejection fraction in the observation group was higher than that in the control group,and the heart rate was lower than that in the control group,and the differences were statistically significant(P<0.05).The total incidence of adverse reactions in the observation group(9.68%)was lower than that in the control group(35.48%),and the difference was statistically significant(P<0.05).
Conclusion
Medical personnel and reasonable choice amiodarone drug treatment for patients with acute cardiac arrhythmias,curative effect and heart function index and safety index can ensure improved significantly,thus lay a foundation for the early rehabilitation of patients with acute arrhythmia,further illustrate choose amiodarone in patients with acute cardiac arrhythmias feasibility of drug treatment.
2019 Vol. 26 (7): 58-60转76 [
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79
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Effect of Trimetazidine combined with coenzyme Q10 in the treatment of chronic heart failure
HUANG Yan-ni
[Abstract]
Objective
To investigate the efficacy of Trimetazidine combined with coenzyme Q10 in the treatment of chronic heart failure.
Methods
A total of 96 elderly patients with chronic heart failure admitted to cardiology department from June 2017 to June 2018 were selected as the subjects,and divided into the treatment group and the control group by random number table method,with 48 cases in each group.The control group was given the routine treatment for chronic heart failure in addition to Trimetazidine.Coenzyme Q10 was added to the treatment group on the basis of the control group.The serum N-terminal pro brain natriuretic peptide (NT-proBNP),heart fatty acid binding protein(H-FABP),Nexilin and cardiac function were compared between the two groups before and after treatment.
Results
After treatment,the serum levels of NT-proBNP,H-FABP and Nexilin in the two groups were lower than those before treatment,and the differences were statistically significant(P<0.05).The serum levels of NT-proBNP,H-FABP and Nexilin in the treatment group were lower than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the level of stroke volume(SV)and left ventricular ejection fraction(LVEF)in the observation group were higher than those in the control group,and Left ventricular end-systolic volume index(LVESVI)and Left ventricular end-diastolic volume index (LVEDVI)were lower than those in the control group,and the differences were statistically significant(P<0.05).
Conclusion
Trimetazidine combined with coenzyme Q10 can significantly reduce the levels of NT-proBNP,H-FABP and Nexilin in elderly patients with chronic heart failure,and improve cardiac function,which is worthy of clinical promotion.
2019 Vol. 26 (7): 61-64 [
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Analysis of the role of dynamic electrocardiographic monitoring for rational arrhythmia in geriatric diseases
GUO Rui
[Abstract]
Objective
To explore the role of dynamic electrocardiographic (ECG)monitoring for rational arrhythmia in geriatric diseases.
Methods
A total of 80 cases of rational arrhythmia in geriatric diseases admitted to our hospital from May 2015 to May 2018 were selected as the objects,and all patients were clinically diagnosed by routine electrocardiogram and dynamic electrocardiogram,and the diagnosis Results of two kinds of electrocardiogram were compared and analyzed.The relationship between arrhythmia and disease in patients were observed.
Results
The detection rates of early beat detection,atrial early beat,atrial velocity,ventricular block,atrial block and ventricular velocity were significantly higher than those of conventional electrocardiogram,and the differences were statistically significant(P<0.05).There was no statistically significant difference in the detection rate of ventricular velocity,sinus stoppage and sinus block between patients with routine electrocardiogram and dynamic electrocardiogram atrial fibrillation (P>0.05).
Conclusion
Dynamic ECG monitoring is carried out in patients with senile rational arrhythmia,and its monitoring is accurate to significantly higher than that of conventional electrocardiogram,which can show the cardiac function of patients more accurately,reduce the rate of missed diagnosis,safe and effective diagnosis,and reliable basis for the diagnosis and treatment of patients,and has the value of clinical use and popularization.
2019 Vol. 26 (7): 65-67 [
Abstract
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78
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68
Application effect of three-dimensional speckle tracking technology in the changes of left ventricular systolic function in patients with aortic stenosis
JIAO NiZHU Fang DING Ming-yan ZHAO Han-zhang LI Jing ZHANG Hui-hui
[Abstract]
Objective
To explore the effect of three-dimensional speckle tracking on left ventricular systolic function in patients with aortic stenosis.
Methods
A total of 50 patients with aortic stenosis treated in our hospital from October 2017 to August 2018 were selected as the subjects,the two-dimensional speckle tracking technology(control group)and three-dimensional speckle tracking technology were used to perform a heart scan(observation group).Echocardiographic parameters(left ventricular end-systolic diameter[LVESD],left ventricular ejection fraction[LVEF],left ventricular posterior wall end-diastolic thickness[LVPWd],and ventricular septum thickness[IVST])were observed.The speckle tracking technical parameters of the two techniques(left ventricular global area strain[GAS],left ventricular global circumferential strain[GCS],left ventricular global long axis strain[GLS],left ventricular global radial Strain[GRS]and three-dimensional strain [3D-strain])were compared.And the correlation between the overall strain values of the left ventricle and LVEF and IVST were analyzed.
Results
The VLEDD,LVESD,LVEF,LVPWd and IVST of patients were(47.83±3.11)mm,(27.01±2.24)mm,(60.70±1.95)%,(10.62±0.75)mm,and(12.63±0.90)mm,respectively.GAS and GCS of the observation group were higher than those of the control group,GLS and GRS were lower than those of the control group,and the differences were statistically significant(P<0.05),3D-strain was(32.60±4.54)%.GAS,GCS,GLS and LVEF were negatively correlated.GRS and 3D-strain were positively correlated with LVEF (P<0.05).GCS,GRS and 3D-strain were negatively correlated with IVST,and GLS was positively correlated with IVST (P<0.05).
Conclusion
Three-dimensional speckle tracking technology can accurately evaluate the left ventricular systolic function changes in patients with aortic stenosis,and can provide valuable data for the development of clinical treatment plans for reference.
2019 Vol. 26 (7): 68-70 [
Abstract
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69
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71
Effect of Irbesartan hydrochlorothiazide combined with Metoprolol in the treatment of elderly patients with severe heart failure
HUANG Shu-wei1YAO Wei-xue1▲ SONG Zhi2KE Dao1KE Zi-fen2
[Abstract]
Objective
To explore the clinical effect and application value of Irbesartan hydrochlorothiazide combined with Metoprolol in the treatment of elderly patients with severe heart failure.
Methods
From January 2017 to March 2018,96 cases of elderly patients with severe heart failure were selected as the study subjects in the emergency department and cardiology department of Zhanjiang Central People′s Hospital.They were divided into group A(conventional treatment)and Group B (conventional treatment combined with irbesartan hydrochlorothiazide and metoprolol)by the random number table method,with 48 cases in each group.The clinical efficacy and cardiac function recovery for the two groups were compared at 3 months and 6 months.
Results
The total effective rate of treatment in group B were higher than that in group A at 3 and 6 months,and the differences were statistically significant(P<0.05).The left ventricular ejection fraction (LVEF)of the two groups at 3 and 6 months afthe treatment were higher than that pre-treatment,and the patientsand heart rate (HR),B-type natriuretic peptide (BNP),systolic blood pressure (SBP),diastolic blood pressure (DBP)were lower than those pre-treatment,and the differences were statistically significant(P<0.05).At 3 and 6 months after treatment,the LVEF of group B were higher than that of group A,while the HR,BNP and SBP in group B were significantly lower than that of group A (P<0.05).At 3 months after treatment,the DBP of the group B was lower than that of group A,and the difference was statistically significant(P<0.05).There were no significant diff erence in the cardiac function of the two groups in the pre-treatment(P>0.05).The cardiac function in the two groupsat3 and 6 monthsaftertreatmentwere significantly better than pre-treatment (P<0.05).The cardiac function in group B were significantly better than that in group A at 3 and 6 months after treatment,and the differences were statistically significant (P<0.05).
Conclusion
Conventional treatment combined with Irbesartan hydrochlorothiazide and Metoprolol is a safe and effective treatment for elderly patients with severe heart failure.It can significantly improve the clinical symptoms and cardiac function of patients in the short-term and long-term applications.The cardiac function recovery of Patients have a better prognosis.which is worthy applying and promoting in clinical practice.
2019 Vol. 26 (7): 71-76 [
Abstract
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77
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77
Effect of mode of human occupation on psychological resilience and social function of patients with schizophrenia
GUO YiFU Chun-lian▲ ZHANG Zhi-bin
[Abstract]
Objective
To explore the effect of mode of human occupation (MOHO)on psychological resilience and social function of patients with schizophrenia.
Methods
A total of 80 patients with schizophrenia who were admitted to our hospital from January 2017 to January 2018 were selected as the research subjects and they were divided into the research group and the control group according to the random number table method，40 cases in each group.The control group was treated with medicine and general work and amusement therapy,and the research group was given the medicine and MOHO therapy.The positive and negative symptom scale (PANSS),the adult mental rehabilitation force scale(RSA),and the social function deficit screening scale(SDSS)were used to evaluate patients of the two groups before treatment and 6 months after treatment.
Results
There were no significant differences in PANSS scores between the two groups before treatment(P>0.05).The total scores of PNASS,positive symptoms,negative symptoms and general pathological scores of the two groups after treatment were lower than those before treatment,and the differences were statistically significant(P<0.05).The total scores of PNASS,negative symptoms and general pathological scores in the research group after treatment were lower than those in the control group,and the differences were statistically significant(P<0.05).There were no significant differences in RSA scores between the two groups before treatment(P>0.05).The RSA scores of the patients in the research group after treatment were significantly higher than those before treatment and in the control group,and the differences were statistically significant(P<0.05).There were no significant differences in the SDSS scores between the two groups before treatment(P>0.05).The SDSS scores of the two groups after treatment were significantly lower than those before treatment,and the differences were statistically significant (P<0.05).The SDSS score after treatment in the research group was lower than that in the control group,and the difference was statistically significant(P<0.05).
Conclusion
MOHO can improve the psychological resilience and social function of schizophrenia patients,which is better than general work and amusement therapy.It has positive effect on the patients′recovery and returning to society,which is worthy of promotion and application.
2019 Vol. 26 (7): 77-80 [
Abstract
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78
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81
Effect of scalp acupuncture therapy on recovery of motor function in patients with stroke
LI Xiao-quan1ZHANG Lei2
[Abstract]
Objective
To explore the effect of scalp acupuncture therapy on recovery of motor function in patients with stroke.
Methods
A total of 78 stroke patients with motor dysfunction admitted to Shenyang Hunhe New Town Hospital of Integrated Traditional Chinese and Western Medicine from January to December 2016 were selected as the study subjects.According to the computer sorting method,the patients were divided into control group(40 cases)and observation group(38 cases).The control group was treated with exercise therapy,while the observation group was treated with scalp acupuncture on the basis of exercise therapy.The limb function score and daily living ability score before after treatment were compared between the two groups.The incidence of falls at the 2
nd
and 6
th
weeks of treatment were recorded in the two groups.
Results
There were no significant difference in the scores of limb function and daily living ability between the two groups before treatment(P>0.05).The scores of limb function and daily living ability in the two groups at the 2
nd
and 6
th
weeks of treatment were higher than those before treatment,and the differences were statistically significant(P<0.05).The scores of limb function and daily living ability in the observation group at the 6th week of treatment were higher than those in the control group,and the differences were statistically significant(P<0.05).All patients in the control group fell 7 times at the 2
nd
week of treatment and 18 times at the 6
th
week of treatment.All patients in the observation group fell 8 times at the 2
nd
week of treatment and 12 times at the 6
th
week of treatment.In the observation group,the number of falls at the 6
th
week of treatment decreased compared with the control group.
Conclusion
Scalp acupuncture can improve the recovery of motor function in stroke patients,and the number of falls reduces after the treatment of scalp acupuncture.
2019 Vol. 26 (7): 81-83转87 [
Abstract
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81
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84
Randomized controlled study of three kinds of hemostasis Methods of manual compression,vascular compression device and vascular suturing device in the application of cerebrovascular intervention
HUANG Wen-yongQIN De-guangYANG LingCHEN Jian-gen HUANG Zhi-peng
[Abstract]
Objective
To investigate the clinical effect of three kinds of hemostasis Methods of manual compression,vascular compression device and vascular suturing device in the application of cerebrovascular intervention.
Methods
A total of 102 patients who underwent the transfemoral intervention therapy from March 2017 to April 2018 in our department were selected as research subjects.According to the medical record number,they were randomly divided into the manual compression group(40 cases,manual compression hemostasis),the vascular compression device group(40 cases,vascular compression device hemostasis)and the vascular suturing device group (22 cases,vascular suturing device hemostasis).The minimum internal diameter of the femoral artery and the peak velocity of the systolic blood flow before operation and 1 day and 3 months after operation were measured at the puncture site and around 3 cm of femoral artery among the three gruops.The thrombosis,arteriovenous fistula and pseudoaneurysm were observed and complications(hematoma,decreasing blood pressure and heart rate)were compared among the three gruops.
Results
There were no significant differences in the minimum internal diameter of the femoral artery and the peak velocity of the systolic blood flow among the three groups before operation(P>0.05).The minimum internal diameter of the femoral artery at 1 day and 3 months after operation in the vascular suturing device group was significantly smaller than that in the manual compression group and the vascular compression device group,the peak velocity of the systolic blood flow at 1 day and 3 months after operation in the vascular suturing device group was significantly lower than that in the manual compression group and the vascular compression device group,and the differences were statistically significant(P<0.05).No thrombosis,arteriovenous fistula and pseudoaneurysm occurred among the three gruops.The total incidence rate of com-plications in the vascular suturing group was significantly lower than that in the manual compression group and the vascular compression device group,and the difference was statistically significant(P<0.05).The total incidence rate of complications in the vascular compression device group was significantly lower than that in the manual compression group,and the difference was statistically significant(P<0.05).
Conclusion
The hemostasis of vascular sutures after cerebral vascular femoral artery puncture can reduce the incidence rate of postoperative complications,the patients′comfort is higher,and the onset is rapid,which is worthy of clinical promotion.
2019 Vol. 26 (7): 84-87 [
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82
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88
Effect of electroconvulsive shock in the treatment of refractory schizophrenia
LIU Long-ping1PAN Rong-xin2HU Yan-ping1HU Xin-xin1ZHANG Xiao-hong1
[Abstract]
Objective
To investigate the clinical effect of electroconvulsive shock in the treatment of refractory schizophrenia.
Methods
The clinical data of 50 patients with refractory schizophrenia treated in our hospital from January 2017 to June 2018 were retrospectively analyzed.They were divided into the observation group(25 cases)and the control group (25 cases)according to the different treatment schemes.The patients in control group were treated with Risperidone and the patients in observation group were treated with electroconvulsive shock.The clinical treatment effect,the positive and negative symptom scales(PANSS)scores and the changes in the Wisconsin card sorting test(WCST)Results before and after treatment and the total incidence rate of adverse reactions during treatment were compared between the two groups.
Results
The total effective rate of the observation group was slightly higher than that of the control group,but the difference was not statistically significant(P>0.05).There were no significant differences in PANSS scores between the two groups at admission(P>0.05).The PANSS scores at 2,5,and 9 weeks after treatment in the two groups were significantly lower than those at admission,and the differences were statistically significant(P<0.05).The PANSS scores at 2,5,and 9 weeks after treatment of the observation group were lower than those of the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the WCST between the two groups at admission(P>0.05).The total number of tests,the number of false responses and the number of persistent errors at 9 weeks after treatment in the two groups were significantly lower than those at admission,the number of completed classifications was significantly higher than that at admission,and the differences were statistically significant(P<0.05).The total number of tests,the number of false responses and the number of persistent errors at 9 weeks after treatment in the observation group were significantly lower than those in the control group,the number of completed classifications was significantly higher than that in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the total incidence rate of adverse reactions between the two groups during treatment(P>0.05).
Conclusion
The effect of electroconvulsive shock is similar to that of Risperidone in the treatment of refractory schizophrenia and both have fine safety.However,electroconvulsive shock is more effective in improving the positive and negative symptoms of patients,which is worthy of clinical recommendation.
2019 Vol. 26 (7): 88-91 [
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84
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92
Early diagnosis and treatment analysis of contralateral progressive epidural hematoma after acute subdural hematoma removal and decompressive craniectomy
CHEN Bin YANG Shao-feng LI Yong-sheng LUO Li-lan
[Abstract]
Objective
To investigate the effect of early diagnosis and treatment of contralateral progressive epidural hematoma after acute subdural hematoma removal and decompressive craniectomy.
Methods
The clinical data of 40 patients with contralateral progressive epidural hematoma after acute subdural hematoma clearance and decompressive craniectomy treated in our hospital from March 2014 to February 2017 were retrospectively analyzed.According to the different treatment methods,they were divided into control group (conservative treatment)and observation group(hematoma removal),20 cases in each group.The time and location of diagnosis,prognosis and hospitalization time were compared between the two groups.
Results
There was no significant difference between the two groups in the time and the proportion of diagnosis location(P>0.05).The recovery rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).The hospitalization time of the observation group was significantly shorter than that of the control group,and the difference was statistically significant(P<0.05).
Conclusion
Early diagnosis of contralateral progressive epidural hematoma after acute subdural hematoma clearance and decompressive craniectomy and selection of effective treatment is the key to improving the prognosis of patients.
2019 Vol. 26 (7): 92-94 [
Abstract
] (
71
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95
Effect comparison of endovascular embolization and vascular clipping for the acute phase of intracranial aneurysm rupture
LIU Guo-hua1ZHOU Yu-fan1YI He-juan2CHENG Zhi-gang1
[Abstract]
Objective
To compare the effect of endovascular embolization and vascular clipping for the acute phase of intracranial aneurysm rupture.
Methods
A total of 157 patients with acute intracranial aneurysm rupture from March 2016 to January 2018 admitted to the First People′s Hospital of Fuzhou in Jiangxi Province were enrolled in the study.They were divided into the observation group 1(n=81,treated with vascular clamping)and the observation group 2(n=76,treated with endovascular embolization)according to the random number table method.The surgical indexes(intraoperative blood loss,medical expenses,hospitalization time)and postoperative complications were compared between the two groups.All patients were followed up for 6 months in the outpatient department to observe the prognosis of the two groups.
Results
The intraoperative blood loss of the observation group 2 was less than that of the observation group 1,the medical expenses were higher than that of the observation group 1,the hospitalization time was shorter than that of the observation group 1,and the differences were statistically significant(P<0.05).There was no significant difference in the good prognosis rate between the two groups (P>0.05).The postoperative infection rate of the observation group 2 was lower than that of the observation group 1,the incidence rate of vasospasm was higher than that of the observation group 1,and the differences were statistically significant(P<0.05).There were no significant differences in the incidence rates of postoperative cerebral ischemia,aneurysm rupture and total complications between the two groups(P>0.05).
Conclusion
Both endovascular embolization and vascular clipping used for the treatment of acute intracranial aneurysm rupture can obtain the good prognosis.The former has less intraoperative blood loss,faster postoperative recovery and lower infection rate,while the latter has lower medical expenses and less vasospasm.
2019 Vol. 26 (7): 95-97转101 [
Abstract
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65
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98
Effect of clearance of hematoma by craniotomy with small bone window in the treatment of hypertensive cerebral hemorrhage
YI Xin-feng BAO Hong WU Kai-hua DING Xuan ZHAO Jian-hua AN De-zhu
[Abstract]
Objective
To explore the clearance of hematoma by craniotomy with small bone window in the treatment of hypertensive cerebral hemorrhage.
Methods
A total of 80 patients with hypertensive cerebral hemorrhage from January 2015 to January 2018 treated in our hospital were selected as research objects and they were divided into the observation group and the control group accroding to the random number table method,40 cases in each group.The control group was given the clearance of hematoma by craniotomy with big bone flap,and the observation group was given the clearance of hematoma by craniotomy with small bone window.Surgical related indicators(operation time,hospitalization time,intraoperative blood loss,hospitalization cost),Glasgow coma scale (GCS)score before and after surgery,modified Barthel index (MBI)score at 3 months after surgery and postoperative complications were compared between the two groups.
Results
The operation time and hospitalization time in the observation group were shorter than those in the control group,the intraoperative blood loss was less than that in the control group,the hospitalization cost was lower than that in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the preoperative GCS score between the two groups(P>0.05).The GCS scores after surgery of the two groups were significantly higher than those before surgery,and the differences were statistically significant(P<0.05).The GCS scores of the patients after surgery and the MBI scores at the 3 months after surgery in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The total incidence rate of complications in the observation group was 12.50%,which was lower than that in the control group (32.50%),and the difference was statistically significant(P<0.05).
Conclusion
Clearance of hematoma by craniotomy with small bone window has definite curative effect,and it can shorten the operation time and hospitalization time,reduce the intraoperative hemorrhage and postoperative complications,reduce medical costs,which is worthy of clinical application.
2019 Vol. 26 (7): 98-101 [
Abstract
] (
67
)
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102
Clinical features of acute stroke complicated with brain-heart syndrome
HU YingZHANG Xin
[Abstract]
Objective
To explore the clinical features and pathogenesis of acute stroke complicated with brain-heart syndrome,and provide reference for clinical diagnosis and treatment.
Methods
A total of 142 patients with acute stroke and onset 1-72 h who were admitted to the department of neurology in our hospital from January 2017 to October 2018 were enrolled,aged 45-88 years,mean (66.5±4.48)years old.The clinical data of 82 patients complicated with brainheart syndrome were studied and analyzed.
Results
The proportion of brain-heart syndrome after acute stroke was 57.75%.The incidence rate of ischemic stroke was 49.07%,and the incidence rate of hemorrhagic stroke was 85.29%,characterized by a variety of changes in electrocardiogram,including various forms of arrhythmia,ST-T changes,abnormal changes in myocardial enzymes,troponin I,and B-type natriuretic peptide precursors (NT-proBNP).Echocardiography showed that 26 cases of local ventricular wall abnormalities(31.71%),except for 2 deaths,and other patients recovered within 1 to 2 weeks.
Conclusion
The incidence rate of hemorrhagic stroke in acute stroke complicated with brain-heart syndrome is significantly higher than that in ischemic stroke.Brain-heart syndrome manifests as abnormal electrocardiogram,myocardial enzyme changes,and cardiac dysfunction.Cardiac changes can be gradually restored after standard treatment.
2019 Vol. 26 (7): 102-104 [
Abstract
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65
)
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105
Comparison of laparoscopic and balloon dilatation in the treatment of lower ureteral stricture
WU Shi-jie LIANG Zhi-qiang MO Xun WANG Shi-hua DAI Si-min
[Abstract]
Objective
To evaluate the efficacy of laparoscopic surgery and balloon dilatation in the treatment of lower ureteral stenosis,to provide guidance for the selection of clinical operation methods.
Methods
From January 2015 to January 2018,35 patients with lower ureteral stenosis in our hospital were selected and divided into laparoscopic group(n=16)and balloon dilatation group (n=19)according to different surgical methods.The patients in the laparoscopic group were treated by laparoscopic resection of ureteral stricture section reanastomosis,and the patients in the balloon dilatation group were treated by transurethral ureteral balloon dilatation.All patients were followed up for 6 months after treatment.The differences in clinical treatment,operative time,intraoperative bleeding,postoperative hospital stay and complications were compared between the two groups.
Results
There was no significant difference in the effect of clinical treatment and the total incidence of postoperative complications between the two groups(P＞0.05）.The operative time and hospital stay in the laparoscopic group were longer than those in the balloon dilatation group (P＜0.05）,and the amount of intraoperative bleeding was more than that in the balloon dilatation group (P＜0.05）,the re-stenosis rate of laparoscopic group was 0.00%,significantly lower than that of balloon dilatation group(26.32%),the differences were statistically significant(P<0.05）.
Conclusion
Laparoscopic surgery and balloon dilatation in the treatment of lower ureteral stricture is basically the same efficacy and safety.For ureteral stricture segment 1.0 cm or less,balloon dilatation is recommended for treatment.For ureteral stricture segment 1.0 cm or more,laparoscopic surgery is recommended.
2019 Vol. 26 (7): 105-107 [
Abstract
] (
69
)
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108
Clinical effect of L-Carnitine combined with hemodialysis on uremic peripheral neuropathy
ZHAN Han-lin
[Abstract]
Objective
To analyze the effect of L-Carnitine combined with hemodialysis(HD)in the treatment of uremic peripheral neuropathy.
Methods
Sixty patients with uremic peripheral neuropathy admitted to our hospital from January 2016 to October 2018 were enrolled in the study.According to the random number table method,they were divided into study group 1 (30 cases)and study group 2 (30 cases).Study group 1 was treated with HD,and study group 2 was treated with L-Carnitine combined with HD.The improvement rate of symptoms and the total effective rate of treatment were compared between the two groups.
Results
The improvement rate of acral pain,sensory disturbance,numbness and restless legs syndrome in the study group 2 were significantly higher than those in the study group 1(P＜0.05）.The total effective rate of the study groups 2 was 90.00%,which was significantly higher than that of the study group 1(66.67%）,the difference was statistically significant(P＜0.05）.
Conclusion
L-Carnitine combined with HD in the treatment of uremic peripheral neuropathy can effectively increase the speed of related nerve conduction and improve the efficiency of treatment.
2019 Vol. 26 (7): 108-110 [
Abstract
] (
58
)
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13
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111
Influence of needle knife loosening vertebral occipital muscle combined with hyperbaric oxygen therapy on hemodynamics in patients with cervical spondylosis
XU FengWANG Hong
[Abstract]
Objective
To investigate the influence of needle knife loosening vertebral occipital muscle combined with hyperbaric oxygen therapy on hemodynamics in patients with cervical spondylosis.
Methods
Seventy patients with vertebral-artery cervical vertebrae treated in our hospital from December 2016 to December 2017 were selected.They were randomly divided into the observation group(n=35)and control group(n=35).In the control group,Western medicine for blood vessels dilation was used,while in the observation group,needle knife loosening vertebral occipital muscle combined with hyperbaric oxygen therapy was adopted.The clinical treatment effect between the two groups was compared.
Results
The total effective rate in the observation group was 97.14%,which was significantly higher than that in the control group (P<0.05).The hemodynamic parameters of the observation group were obviously better than those of the control group (P<0.05).
Conclusion
Needle knife loosening vertebral occipital muscle combined with hyperbaric oxygen treating cervical spondylosis can significantly improve the clinical symptoms of patients,so that hemodynamic indicators gradually return to normal,which help patients to recover health as soon as possible.
2019 Vol. 26 (7): 111-113转123 [
Abstract
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65
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114
Clinical effect of internal fixation combined with anti-osteoporosis drugs in the treatment of distal radius fracture in the elderly
LI Bin
[Abstract]
Objective
To investigate the clinical effect of internal fixation combined with anti-osteoporosis drugs in the treatment of distal radius fracture in the elderly.
Methods
All of 80 elderly patients with distal radius fracture treated in our hospital from March 2016 to March 2017 were selected as study objects,and they were divided into the study group (40 cases)and control group (40 cases)according to the parallel control method.The study group was treated with internal fixation combined with anti-osteoporosis drugs,while the control group was treated with internal fixation alone.The fracture healing time,BMD value,wrist joint function score and clinical efficacy were compared between the two groups.
Results
The healing time of fracture in the study group was shorter than that in the control group (t=26.249,P=0.000).BMD in the study group was higher than that in the control group at 6 months and 12 months after operation(t=2.626,2.975,P=0.005,0.002).Cooney wrist joint function score in the study group was higher than that in the control group at 6 months and 12 months after operation (t=11.452,22.289,P=0.000,0.002).The excellent and good rate of the study group(92.50%)was higher than that of the control group(75.00%)(χ
2
=4.501,P=0.034).
Conclusion
Internal fixation combined with anti-osteoporosis drugs in the treatment of distal radius fracture in the elderly can better improve bone mineral density and joint function,promote fracture healing as soon as possible,which is worthy of clinical promotion.
2019 Vol. 26 (7): 114-116 [
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] (
66
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117
A randomized controlled study of DHS,LPFP and PFNA in the treatment of intertrochanteric fracture of the femur in the elderly
LIANG FeiTAN Zhe-jun HE Li-liFANG Hui-qiang WAN Fu-gui
[Abstract]
Objective
To compare the clinical effect of dynamic hip screw (DHS),proximal femoral locking plate(LPFP),Proximal femoral anti-rotation intramedullary nail(PFNA)in the treatment of intertrochanteric fracture of the femur in the elderly.
Methods
All of 120 elderly patients with intertrochanteric fracture of femur admitted to our hospital from January 2017 to September 2018 were selected as the research objects.According to random ranking method,they were divided into the DHS group,LPFP group and PFNA group,40 cases in each group.The operation time,intraoperative bleeding volume,hospital stay and weight-bearing time,the incidence of complications,Harris hip function score before operation and at 2 weeks and 1 month after operation were compared among the three groups.
Results
The operation time,hospitalization time and weight-bearing time of the PFNA group were shorter than those of the DHS and LPFP group,and the intraoperative bleeding volume was less than that of the DHS and LPFP group,and the differences were statistically significant(P<0.001).There was no significant difference in the total incidence of complications among the three groups(P>0.05).The Harris hip function score of the three groups at 2 weeks and 1 month after operation was higher than those before operation,and the differences were statistically significant(P<0.05).The Harris hip function scores of the PFNA group at 2 weeks and 1 month after operation were significantly higher than those of the DHS and LPFP group,and the differences were statistically significant(P<0.001).
Conclusion
For patients with intertrochanteric fracture of femur,PFNA treatment can effectively reduce intraoperative bleeding volume and shorten the operation time,and the patients can move to the ground earlier,and the recovery effect of hip joint is good,the recovery time is short,and complications are not easy to occur after operation.It has better therapeutic effect.
2019 Vol. 26 (7): 117-119转127 [
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51
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Clinical effect of Alfacalcidol Soft Capsules combined with Raloxifene in the treatment of postmenopausal osteoporosis
XIONG Guo-hui1SHENG Xia2YUAN Zhong3▲
[Abstract]
Objective
To explore the clinical effect of Alfacalcidol Soft Capsules combined with Raloxifene in the treatment of postmenopausal osteoporosis.
Methods
A total of 100 patients with postmenopausal osteoporosis admitted to Hongdu Hospital of Traditional Chinese Medicine in Nanchang City from May 2015 to May 2017 were selected and they were divided into the two groups according to computer randomization method.Each group had 50 cases.The control group was given Raloxifene Hydrochloride orally.The experimental group was given Alfacalcidol Soft Capsules combined with Raloxifene.The therapeutic effect,bone strength,bone metabolic markers and the inciedence of adverse reactions were compared between the two groups.
Results
The total effective rate of in the experimental group was higher than that in the control group,and the difference was statistically significant (P<0.05).The levels of bone strength related indicators in the two groups after treatment were higher than those before treatment,and the levels of bone strength related indicators in the experimental group after treatment were higher than those in the control group,and the differences were statistically significant(P<0.05).The levels of bone metabolic markers in both groups after treatment were lower than those before treatment,and the levels of bone metabolic markers in the experimental group after treatment were lower than those in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).
Conclusion
The clinical effect of Alfacalcidol Soft Capsules combined with Raloxifene in the treatment of postmenopausal osteoporosis is better.
2019 Vol. 26 (7): 120-123 [
Abstract
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73
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124
Clinical effect of addition and subtraction of Bushen Zhuanggu Recipe in the treatment of ankylosing spondylitis
ZHAN Chao-gun CHEN Zhuo-hua
[Abstract]
Objective
To explore the clinical effect of addition and subtraction of Bushen Zhuanggu Recipe in the treatment of ankylosing spondylitis(AS).
Methods
A total of 50 patients with AS admitted to our hospital from April 22,2016 to April 22,2018 were selected as study objects and they were divided into the control group(n=25)and observation group (n=25)according to the odd/even number group model.In the observation group,addition and subtraction of Bushen Zhuanggu Recipe was used,while in the control group,Sulfasalazine Tablets was used.The total effective rate,spinal activity degree,thoracic range of motion,finger-to-ground distance,occipital-wall distance,morning stiffness time,lumbar-back pain score,erythrocyte sedimentation rate,serum C-reactive protein and the total incidence of adverse reactions were compared between the two groups.
Results
There was no significant difference in spinal activity,thoracic activity,finger-to-ground distance,occipital wall distance,morning stiffness time,lumbar back pain score,erythrocyte sedimentation rate and serum C-reactive protein before treatment between the two groups(P>0.05).The total effective rate of the observation group(96.00%)was higher than that of the control group(72.00%)(P<0.05).After treatment,the spinal activity degree was(45.85±3.61)°,thoracic range of motion was(3.69±1.47)cm in the observation group,which were higher than those of the control group for(35.68±2.66)°,(2.86±1.33)cm(P＜0.05),finger-to-ground distance was(6.11±1.19)cm,occipital wall distance was(0.33±0.15)cm in the observation group,which were lower than those of the control group for(8.95±1.43),(1.54±0.38)cm(P＜0.05),morning stiffness time was(30.15±3.19)min in the observation group,which were shorter than that of the control group for(35.96±3.55)min(P<0.05),lumbar back pain score was(0.32±0.18)points,erythrocyte sedimentation rate was(14.18±1.28)mm/h,serum C-reactive protein was(4.12±0.46)mg/L in the observation group,which was lower than those of the control group for (1.32±1.55)points,(18.39±2.41)mm/h,(5.11±0.39)mg/L (P<0.05).The total incidence of adverse reactions in the observation group was 28.00%,which was lower than that in the control group(4.00%)(P<0.05).
Conclusion
The effect of addition and subtraction of Bushen Zhuanggu Recipe in the treatment of ankylosing spondylitis is remarkable.
2019 Vol. 26 (7): 124-127 [
Abstract
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62
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128
Application of New Ergometrine combined with Oxytocin in postoperative uterine scar pregnancy curettage
LIU Qiong LAI Hui-chao ZHONG Hua-lan
[Abstract]
Objective
To investigate the application effect of New Ergometrine and Oxytocin in the treatment of postoperative uterine scar pregnancy curettage.
Methods
A total of 48 patients with uterine scar pregnancy treated in our hospital from July 2016 to July 2017 were selected as the study subjects.According to the lots drawing,they were divided into the control group(n=23)and the study group(n=25).In the control group,Oxytocin alone was used,while in the study group,Oxytocin combined with New Ergometrine was adopted.The incidence rate of postoperative bleeding,hysterectomy rate,intraoperative and postoperative bleeding volume and the total incidence rate of adverse reactions were compared between the two groups.
Results
The incidence rate of postoperative bleeding in the study group was lower than that of the control group,the amount of blood loss during operation,2 hours and 24 hours after surgery of the study group were significantly less than those of the control group,with significant differences(P<0.05).There was no significant difference in the rate of hysterectomy or the total incidence rate of adverse reactions between the two groups(P>0.05).
Conclusion
The application of New Ergometrine combined with Oxytocin after uterine scar pregnancy curettage can decrease the incidence of postoperative hemorrhage,and reduce the amount of intraoperative and postoperative bleeding with few adverse reactions,which is of great value for retaining fertility.
2019 Vol. 26 (7): 128-130 [
Abstract
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65
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131
Effect of Ribavirin Aerosol combined with Licorzinc in the treatment of herpetic stomatitis
YU Zhi-xin1XIE Xiao-qin2▲
[Abstract]
Objective
To investigate the effect of Ribavirin Aerosol combined with Licorzinc in the treatment of herpetic stomatitis.
Methods
A total of 72 cases of children with herpetic stomatitis treated in pediatric department of our hospital from January to December 2017 were selected as the subjects of study.They were divided into the observation group and the control group by the random number table method,36 cases in each group.In the observation group,Ribavirin Aerosol combined with Licorzinc was adopted,while in the control group,Ribavirin Aerosol alone was used.The clinical efficacy,the time of fever abating,the time of appetite improvement,the disappearance time of herpes ulcer,white blood count(WBC)and the level of C-reactive protein (CRP)before and after treatment in the two groups were observed and compared.
Results
The total clinical effectiveness rate of the observation group was 91.67%,which was much higher than that of the control group accounting for 63.89%,with significant difference(P<0.05).The fever abating time,appetite improvement time and disappearance time of herpes ulcer in the observation group were greatly shorter than those in the control group,with statistical significances (P<0.05).Before treatment,there were no significant differences in the WBC and levels of CRP between the two groups(P>0.05).After treatment,the WBC and levels of CRP in the two groups were significantly lower than those before treatment,with significant differences(P<0.05).The WBC and levels of CRP in the observation group after treatment were significantly lower than those in the control group,with statistical significances (P<0.05).
Conclusion
The effect of Ribavirin Aerosol combined with Licorzinc in the treatment of herpetic stomatitis is clear.The clinical symptoms are obviously improved,and the WBC and levels of CRP are reduced markedly.It is worthy of clinical application and promotion.
2019 Vol. 26 (7): 131-133 [
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58
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134
Comparison of the clinical effect of the vertical parallel suture of lower segment of uterus and 8-word patch suture in the cesarean section of the patients with placenta previa
ZHOU Li-li
[Abstract]
Objective
To explore the clinical hemostatic effect of the vertical parallel suture of lower segment of uterus in the cesarean section of the patients with placenta previa.
Methods
From January 2016 to August 2017,80 pregnant women with placenta previa delivered in the Department of Obstetrics and Gynecology of our hospital were selected as the research object.They were randomly divided into the control group and the observation group,40 cases in each group.The patients in the control group received the hemostasis after the operation with the use of and the 8-word patch suture,and the patients in the observation group received the hemostasis after the operation with the vertical and parallel compression suture of the lower uterine segment.The bleeding volume,the effective hemostasis rate,hemostasis time,postoperative rebleeding rate and long-term complication rate were compared between the two groups.
Results
The amount of bleeding in the observation group was less than that in the control group,the difference was statistically significant(P＜0.05).The effective hemostasis rate in the observation group was higher than that in the control group,the difference was statistically significant(P＜0.05).The operation time and hospitalization days in the observation group were shorter than those in the control group,the difference was statistically significant(P＜0.05).The rate of postoperative re-bleeding and the total incidence of postoperative complications in the observation group were less than those in the control group,the difference was statistically significant(P＜0.05).
Conclusion
In the caesarean section of the placenta previa,the treatment of the patient by vertical and parallel compression suture of the lower uterine segment can achieve effective hemostasis in a short time,reduce postoperative bleeding and reduce postoperative complications of the patients.
2019 Vol. 26 (7): 134-136 [
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66
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137
Application effect of continuous brain function monitoring in early diagnosis of neonatal hypoxic ischemic encephalopathy
LUO Hui-ling BAI Bo HUANG Nuan-chao GONG Zhan-chao DU Xiao-qun LI Guang-hong▲
[Abstract]
Objective
To study the application effect of continuous brain function monitoring in early diagnosis of neonatal hypoxic ischemic encephalopathy.
Methods
A total of 70 children with neonatal hypoxic ischemic encephalopathy admitted to our hospital from January 2010 to January 2018 were enrolled in the study.They were divided into the control group (n=35)and the observation group (n=35)according to computer randomization.In the control group,MRI and CT were detected,while in the observation group,continuous brain function monitoring was adopted.The degree of brain injury,the normal rates of psychological function and neurological function at 2 and 6 months were compared between the two groups.
Results
There was no significant difference in the normal rate of brain function or mild injury rate between the two groups(P＞0.05).The severe damage rate in the observation group was lower than that in the control group,with significant difference (P＜0.05).In the observation group,the psychological and neurological functions of children with normal brain function at 2 months and 6 months were higher than those with abnormal brain function,with statistical significance(P＜0.05).
Conclusion
Continuous brain function monitoring has a high application value in early diagnosis of neonatal hypoxic ischemic encephalopathy,which can fully reflect the brain function of children and provide a favorable basis for clinical treatment.It is worthy of study.
2019 Vol. 26 (7): 137-139 [
Abstract
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70
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140
Application effect of balloon bionic midwifery in epidural anesthesia for analgesia in delivery women
HAN Chun-ping XIAO Wen-ping LI Juan XIE Xu-juan
[Abstract]
Objective
To investigate the application effect of balloon bionic midwifery in epidural anesthesia for analgesia in delivery women.
Methods
A total of 5440 patients with cesarean section indications,pregnancy complications,single-fetal in head position,contraindications for spinal anesthesia,and the requirement of self-controlled epidural anesthesia were enrolled in our hospital from January to December in 2017.They were divided into the observation group and the control group by a random number table method,with 2720 cases in each group.Both groups underwent epidural anesthesia for analgesia.In the control group,baloon bionic midwifery was not applied,while in the observation group,balloon bionic midwifery was performed.The use of Oxytocin,the time of labor,delivery mode,and postpartum hemorrhage in the two groups were compared.
Results
The labor time of the observation group was significantly shorter than that of the control group,with a statistical difference(P＜0.05).The postpartum hemorrhage of the observation group was less than that of the control group,with significant difference (P＜0.05).The cesarean section rate of the observation group was lower,and the natural delivery rate was higher compared with those of the control group,with statistical significance (P＜0.05).The use rate of Oxytocin in the observation group was lower than that of the control group,with statistical difference (P＜0.05).
Conclusion
Balloon bionic midwifery combined with self-control epidural anesthesia for delivery can increase the vaginal delivery rate,shorten the labor stages,reduce the use of oxytocin and postpartum hemorrhage,decrease the cesarean section rate and improve the quality of obstetrics.
2019 Vol. 26 (7): 140-142 [
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80
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143
pplication effect of Oxytocin combined with Phloroglucinol on delivery of women with low-cervical scores in full-term fetal membranes
CAI Li-hua HE Qian-ying TANG Jin-qing FU Hong-wang
[Abstract]
Objective
To investigate the application effect of Oxytocin combined with Phloroglucinol on the delivery of low-cervical scores in full-term fetal membranes.
Methods
A total of 80 puerpera with low-cervical scores of fullterm fetal membranes in our hospital from August 2016 to January 2017 were selected as subjects.They were divided into the control group(40cases)and the observation group(40cases)according to the random number table method.The control group was treated with uterine contraction by Oxytocin,and the observation group was combined with Oxytocin and Pyrogallol.The cervical ripening effect,labor process,mode of delivery and pregnancy outcomes were compared between the two groups.
Results
The total effective rate of cervical-induced maturation in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).The first labor,second labor,third labor and total labor in the observation group were shorter than those in the control group,and the differences were statistically significant(P＜0.05).The natural vaginal delivery rate of the observation group was significantly higher than that of the control group,and the difference was statistically significant(P＜0.05).The incidence rates of postpartum urinary retention,postpartum hemorrhage＞200 ml,fetal distress and neonatal asphyxia adverse pregnancy outcomes in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).
Conclusion
Combined use of Oxytocin and Phloroglucinol on the delivery of low-cervical scores in full-term fetal membranes can promote cervical ripening and shorten the labor process,and at the same time help to improve the natural delivery rate of vaginal and reduce the incidence rate of adverse pregnancy outcomes,which is worth promoting.
2019 Vol. 26 (7): 143-145转151 [
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71
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146
Clinical effect of pelvic floor neuromuscular electrical stimulation combined with vaginal dumbbell in the treatment of female stress urinary incontinence
JIANG Yan-yan MIAO Li-lin TANG Sai-li
[Abstract]
Objective
To investigate the effectiveness of pelvic floor neuromuscular electrical stimulation combined with Vagina dumbbell for improving female stress urinary incontinence,to find a more economical and effective method to improve the pelvic floor function of patients with urinary incontinence.
Methods
A total of 61 cases women with urinary incontinence in our hospital from January 2015 to June 2018 were selected and randomly divided into group A(30 cases)and group B (31 cases).Group A was given electrical stimulation therapy (2 times a week,a total of 10 times),group B was given electrical stimulation(2 times a week,a total of 10 times)combined with vagina dumbbell(at least 8 to 10 weeks).The ICI-Q-SF score of urinary incontinence symptoms before treatment and 3 months after treatment in the two groups was evaluated by the questionnaire of the International Urinary Incontinence Advisory Committee.The improvement of urinary incontinence and cure rate in the two groups were compared after treatment.
Results
The score of urinary incontinence in the two groups after treatment was significantly lower than that before treatment,the score of urinary incontinence in group B after treatment was significantly lower than that in group A (P＜0.05).The cure rate of urinary incontinence in group B(51.61%)was significantly higher than that of group A(26.67%)(P=0.046).
Conclusion
Pelvic floor neuromuscular electrical stimulation combined with vagina dumbbell can significantly improve pelvic floor muscle function and the symptoms of urinary incontinence in women.
2019 Vol. 26 (7): 146-148 [
Abstract
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71
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149
Influencing factors of intrauterine device incarceration
TU Qin
[Abstract]
Objective
To analyze the related factors affecting the incarceration of the intrauterine device(IUD).
Methods
A retrospective analysis of the clinical data of 48 women with IUD treated in our hospital from January 2014 to July 2018 was conducted by face-to-face conversation,influencing factors of IUD incarceration were discussed.
Results
The presence of dysmenorrhea,the time of IUDs application,the presence of gynecological inflammation,the duration of IUDs application,the presence of pregnancy with IUDs,and the type of IUDs were independent risk factors for the incarceration of the IUD.
Conclusion
When placing the device,comprehensive factors should be considered to choose the appropriate intrauterine device,and regularly postoperative review should be conducted to reduce the incidence of intrauterine device incarceration.
2019 Vol. 26 (7): 149-151 [
Abstract
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64
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152
Application effect of nutrition guidance and weight management intervention in pregnant women
GU Meng-wei
[Abstract]
Objective
To study the effects of nutritional intervention and weight management in pregnant women and the impact on maternal and child outcomes.
Methods
A total of 320 pregnant women who underwent prenatal examination and delivery in our department from June 2015 to June 2017 were enrolled and randomly divided into the observation group and the control group,with 160 patients in each group.Pregnant women in the observation group were given nutritional guidance and weight management intervention during pregnancy,while those in the control group were only given routine prenatal examination during pregnancy.The weight gains of the two groups and the maternal and child outcomes at the time of delivery were compared.
Results
The subjects with excessive body weight in the observation group were fewer than those in the control group,and the difference between the groups was significant(P＜0.05),suggesting that the weight control effect of the pregnant women in the observation group was better.The incidence of diabetes,hypertension and hyperlipidemia in the observation group during pregnancy was lower than that in the control group,and the difference between the groups was significant(P＜0.05).The incidence of cesarean section,postpartum hemorrhage,and large fetus in the observation group was lower than that in the control group,and the difference between the groups was statistically significant(P＜0.05).The biochemical parameters,including low density lipoprotein(LDL),triglyceride(TG),total cholesterol(TC),glycosylated hemoglobin (HbA1c),fasting blood glucose (FPG)levels in the observation group were lower than those in the control group,and the level of high density lipoprotein(HDL)in the observation group was higher than that in the control group (P＜0.05).
Conclusion
Nutritional guidance and weight management in pregnant women can significantly reduce the incidence of overweight,improve various biochemical indicators,and lead to a better pregnancy outcome,which has higher application value and can be further promoted and applied.
2019 Vol. 26 (7): 152-155 [
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76
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156
Clinical effect and safety analysis of modified B-Lynch suture for postpartum hemorrhage
XING Shun-lian OUYANG Fang-lan CHEN Hong-jin
[Abstract]
Objective
To investigate the clinical efficacy and safety of modified B-Lynch suture for postpartum hemorrhage.
Methods
A total of 126 puerperae suffering from postpartum hemorrhage in our hospital from March 2015 to April 1818 were selected as the study subjects.According to the different hemostasis methods,they were divided into the control group(68 cases)and the observation group(58 cases).In the control group,the conventional gauze packing was used for hemostasis,while in the observation group,patients were treated with modified B-Lynch suture for hemostasis.The operation time,intraoperative blood loss,hospital stay,24-hour postpartum hemorrhage volume,hemoglobin changes before and after surgery,and the incidence of complications such as infection,intestinal obstruction,and intestinal adhesion within two weeks after surgery were observed and recorded between the two groups.
Results
There were no significant differences in the operation time and preoperative hemoglobin levels between the two groups(P＞0.05).The intraoperative blood loss and the 24-hour postpartum bleeding in the observation group were lower than those in the control group,with statistical significance (P＜0.05).The hospital stay in the observation group was significantly shorter compared with that of the control group,with a statistical difference (P＜0.05).The incidence of complications in the observation group was significantly lower than that of the control group,with a significant difference (P＜0.05).The postoperative hemoglobin level in the observation group was significantly higher than those in the control group,with statistical significance (P＜0.05).
Conclusion
Modified B-Lynch suture can effectively reduce the amount of bleeding during and 24 hours after surgery,shorten the hospital stay,and effectively reduce the incidence of postoperative complications,which is worthy of clinical application.
2019 Vol. 26 (7): 156-158 [
Abstract
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60
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159
Role of carbohydrate antigen 125 combined with human epididymal secretory protein 4 in the prognosis of patients with ovarian cancer
YANG Nan
[Abstract]
Objective
To explore the role of carbohydrate antigen 125 (CA125)combined with human epididymal secretory protein 4(HE4)in the prognosis of patients with ovarian cancer.
Methods
A total of 256 patients who were diagnosed as ovarian cancer by pathology from January 2010 to May 2014 were selected and followed up for four years.The general data of the patients were analyzed,and univariate and multivariate Cox were used to analyze the prognostic factors such as age,family history,menopausal status,body mass index,treatment methods,lesion diameter,degree of differentiation,staging,pathological type,degree of myometrial invasion,HE4 level and CA125 level.
Results
The single-factor Cox regression showed that the treatment methods,lesion diameter,degree of differentiation,staging,pathological type,degree of myometrial invasion,HE4 and CA125 had significant effects on the prognosis of the disease,and the differences were statistically significant(P＜0.05).Further,multivariate Cox regression showed that lesion diameter,degree of differentiation (G
1
and G
2
),pathological type (serous and mucinous),staging,degree of myometrial invasion,HE4 and CA125 were independent prognostic factors.
Conclusion
CA125 and HE4 are independent risk factors affecting the prognosis of patients with nodular ovarian cancer.They can help to screen patients with poor prognosis.
2019 Vol. 26 (7): 159-161 [
Abstract
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61
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162
Influence of Low Molecular Weight Heparin on hypercoagulable state and perinatal outcome in patients with early onset severe pre-eclampsia
LIANG Zheng-yi
[Abstract]
Objective
To investigate the influence of Low Molecular Weight Heparin on hypercoagulable state and perinatal outcome in patients with early onset severe pre-eclampsia.
Methods
A total of 72 patients with early-onset severe pre-eclampsia who were treated in our hospital from May 2014 to June 2018 were selected and randomly divided into the control group and the observation group,36 cases in each group.The control group was given conventional treatment,and the observation group was treated with Low Molecular Weight Heparin on the basis of the control group.The coagulation function related indicators,perinatal outcomes and complications were compared between the two groups before and after treatment.
Results
There were no significant differences in the indexes of coagulation function between the two groups before treatment(P＞0.05).The prothrombin time and activated partial thrombin time in the observation group after treatment were longer than those in the control group,with significant difference (P＜0.05).There was no significant difference in the levels of fibrinogen,D-dimer and the weight of the newborn between the two groups(P＞0.05).Compared with the control group,the 1 minute Apgar score of the observation group was higher(P＜0.05).The total incidence of complications in the observation group was lower than that in the control group,with significant difference(P＜0.05).
Conclusion
Low Molecular Weight Heparin in the treatment of early-onset severe pre-eclampsia patients is safe,which help to improve blood hypercoagulability and perinatal outcomes,has a certain positive promotion value.
2019 Vol. 26 (7): 162-164 [
Abstract
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82
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165
Influence of progesterone adjuvant therapy on maternal and infant outcomes in pregnancy with uterine fibroids
LIU Juan
[Abstract]
Objective
To investigate the influence of progesterone adjuvant therapy on maternal and infant outcomes in pregnancy with uterine fibroids.
Methods
A total of 48 pregnancy patients with uterine fibroids who were admitted to our hospital from September 2017 to September 2018 were selected as subjects,according to the random number table method,they were divided into the experimental group and the general group,24 cases in each group.The general group was used conventional treatment methods,and the experimental group was used progesterone-assisted treatment.The maternal and infant outcomes were compared between the two groups.
Results
At the time of cesarean section,the progesterone level of the experimental group was higher than that of the general group,and the difference was statistically significant(P＜0.05).There was no significant difference in the size of uterine fibroids between the two groups during early pregnancy and cesarean section (P＞0.05).There was no significant difference in progesterone levels between the two groups(P＞0.05).There was no significant difference in the incidence of adverse events,red degeneration rate of uterine fibroids and progesterone receptor(PR)expression(P＞0.05).There were no significant differences in intraoperative blood loss,operation time,hospital stay,and neonatal Apgar scores(P＞0.05).
Conclusion
Progesterone-assisted treatment of pregnancy with uterine fibroids has no adverse effects on maternal and infant outcomes,and can be applied as appropriate.
2019 Vol. 26 (7): 165-167 [
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51
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168
Clinical effect of Labetalol combined with Magnesium Sulfate in the treatment of hypertensive disorder complicating pregnancy
LIU Yi-xue ZHOU Yan GUAN Xiu-ying
[Abstract]
Objective
To explore the clinical effect of Labetalol combined with Magnesium Sulfate in the treatment of hypertensive disorder complicating pregnancy.
Methods
A total of 50 gestational hypertension patients admitted to our hospital from April 2017 to August 2018 were selected and randomly divided into the control group (25 cases)and the observation group(25 cases).The control group was given Nifedipine combined with Magnesium Sulfate,and the observation group was given Labetalol combined with Magnesium Sulfate.The blood pressure,hemorheology,clinical efficacy and pregnancy outcomes between the two groups were compared.
Results
The systolic blood pressure and diastolic blood pressure in the observation group were lower than those in the control group,and the difference was statistically significant(P＜0.05).After treatment,the 24 h urine protein,hematocrit and blood viscosity of the observation group were higher than those of the control group,the difference was statistically significant(P＜0.05).The total effective rate of treatment in the observation group(92.00%)was significantly higher than that in the control group(64.00%),and the difference was statistically significant(P＜0.05).The pregnancy outcome of the observation group was better than that of the control group,and the difference was statistically significant(P＜0.05).
Conclusion
Pregnancy-induced hypertension in pregnant women with Labetalol combined with Magnesium Sulfate can achieve good antihypertensive effect,significantly improve pregnancy outcome.Nifedipine combined with Magnesium Sulfate in the improvement of hemodynamics and renal function is better than Labetalol combined with Magnesium Sulfate.This is worthy of clinical promotion and application.
2019 Vol. 26 (7): 168-170 [
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66
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171
Analysis of the relationship between dietary factors in pregnancy and hypertensive disorders in pregnancy
CHENG Fu-rong DONG Jin-lian QIN Yu-ting
[Abstract]
Objective
To explore the relationship between dietary factors and gestational hypertension(HDCP)in pregnant women.
Methods
A total of 180 patients with HDCP who were treated from January 2016 to January 2018 in our hospital were selected as the observation group.At the same time,180 pregnant women who underwent routine physical examination were selected as the control group.The types and fkquency of various foods intake during pregnancy were investigated by questionnaires.The dietary scores of pregnant women in the two groups were compared.The dietary factors affecting HDCP were analyzed by single factor and multiple Logistic regression.
Results
The dietary scores of meat,eggs,milk,beans and nuts intake in the observation group were significantly lower than those of the control group,with significant difference(P＜0.01),while the dietary scores of pickles intake in the observation group was significantly higher than that of the control group,with significant difference(P＜0.01).Logistic regression analysis showed that intake of eggs(OR=0.771)and milk (OR=0.808)were the protective factors of HDCP (P＜0.01),while intake of pickles(OR=1.179)was the risk factor of HDCP(P＜0.01).And eggs and milk were protective factors,but pickles were risk factors.
Conclusion
Intake of eggs and milk can effectively prevent or reduce the incidence of HDCP,while intake of pickles would increase the risk of HDCP.
2019 Vol. 26 (7): 171-173 [
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73
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Effect comparison of different dosage of Prednisolone combined with Clomiphene in the treatment of hyperandrogenic infertility in patients with polycystic ovary syndrome
LIANG Fa-liang1TAN Wen-qiang1LIANG Bao-zhu2ZHONG Mei-gong1WU Zhuo-jian1
[Abstract]
Objective
To compare the effect of different dosage of Prednisolone combined with Clomiphene in the treatment of hyperandrogenic infertility in patients with polycystic ovary syndrome (PCOS).
Methods
A total of 160 PCOS patients with hyperandrogenic infertility who visited gynecology clinic in our hospital from January 2017 to April 2018 were selected as the study subjects,and divided into group A,group B,group C and group D by random number table method,with 40 cases in each group.Group D as the control group was treated with Clomiphene 50 mg/d×5 d,while group A,group B and group C were treated with Prednisolone Tablets 20 mg/d,15 mg/d and 10 mg/d respectively.They were all treated for 3 days.After treatment,the reproductive hormone levels of testosterone(T),luteinizing hormone(LH),estradiol(E
2
)and follicle stimulating hormone(FSH),the number and diameter of mature follicles,the number and diameter of dominant follicles,ovulation rate and pregnancy rate were compared.
Results
The T level of group C was significantly lower than that of group A,group B and group D,and the levels of LH,E
2
and FSH were significantly higher than those of group A,group B and group D (P<0.05).The diameter of mature follicles in group C was significantly longer than that in group A,group B and group D (P<0.05).There was no significant difference in the number of mature follicles,the number of dominant follicles and the thickness of endometrium among group A,group B,group C and group D (P>0.05).The ovulation rate in group A,group B and group C was significantly higher than that in group D (P<0.05).There was no significant difference in pregnancy rate among group A,group B,group C and group D (P>0.05).
Conclusion
The optimal dose of Prednisolone combined with Clomiphene in the treatment of PCOS hyperandrogenic infertility is 10 mg/d,which can effectively reduce the level of androgens in vivo,improve the level of estrogen,and has a significant effect on promoting ovulation and pregnancy.
2019 Vol. 26 (7): 174-176转179 [
Abstract
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58
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177
Analysis of irrational medical orders of pharmacy intravenous admixture service in our hospital
ZHAO Sen ZHOU Ai-hua WU Lin-lin JIANG Li▲
[Abstract]
Objective
To analyze the unreasonable medical orders of pharmacy intravenous admixture service(PIVAS),to understand the unreasonable medical orders,and to formulate the"matters needing attention for clinical intravenous drug use"in our hospital,so as to ensure the safety,rationality and effectiveness of clinical drug use.
Methods
in September,2018,unreasonable doctors′orders were selected from the venous drug dispensing center of our hospital in 12 months of 2017 and unreasonable doctors′orders were collected and analyzed 8 months after the formulation of notes for common clinical intravenous drug use.
Results
In 2017,there were 2254 unreasonable medical orders,accounting for 0.53%.A total of 118 unreasonable medical orders,accounting for 0.04%,were formulated after"matters needing attention for common clinical intravenous drug use".The main reasons for unreasonable doctors′advice were unreasonable selection of solvent and unreasonable dosage of solvent.
Conclusion
Designed to department as the unit of the clinical commonly used intravenously matters needing attention,issued to the clinical departments,to guide the clinical medication of normative,unreasonable medical advice rate dropped significantly,can be used as PIVAS pharmacist prescription audit evaluation criteria,to live from physicians,provide reference for new nurses,in the specification the doctors′advice and the rational use of drugs has played a very good guide.
2019 Vol. 26 (7): 177-179 [
Abstract
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72
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180
Application evaluation of Huatan Quyu Tongmai Decoction in the treatment of unstable angina pectoris of coronary heart disease
GUO Liang
[Abstract]
Objective
To analyze the effect of self-made Huayu Quyu Tongmai Decoction on unstable angina pectoris of coronary heart disease.
Methods
A total of 82 patients with coronary heart disease with unstable angina treated in our hospital from June 2016 to January 2018 were selected as study subjects and divided into experimental group(41 cases)and control group (41 cases)according to the random number table method.Patients in the experimental group were treated with self-made Huatan Quyu Tongmai Decoction for treatment,and the control group was treated with conventional western medicine.The treatment effect,the number of episodes of angina pectoris,the duration of angina pectoris,the score of Traditional Chinese Medicine (TCM)clinical symptoms,and the hemorheological indexes were compared between the two groups.
Results
The total therapeutic rate of the experimental group was higher than that of the control group,and the difference was statistically significant(P<0.05).The number of episodes of angina pectoris in the experimental group was less than that of the control group,the difference was statistically significant(P<0.05).The duration of angina pectoris in the experimental group was shorter than that of the control group,the difference was statistically significant(P<0.05).The scores of TCM clinical symptoms in the experimental group were lower than those in the control group,the differences were statistically significant(P<0.05).The hemorheology indexes in the experimental group were lower than those in the control group,and the differences were statistically significant(P<0.05).
Conclusion
Self-made Huayu Quyu Tongmai Decoction is effective in treating unstable angina pectoris of coronary heart disease.The number of episodes of angina pectoris is reduced,which is worthy of clinical promotion and application.
2019 Vol. 26 (7): 180-182 [
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67
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183
Effect of traditional Chinese medicine therapy of reinforcing qi and activat blood in the treatment of coronary heart disease patients with myocardial ischemia
GAO Fang
[Abstract]
Objective
To explore the effect of traditional Chinese medicine (TCM)therapy of reinforcing qi and activat blood in the treatment of coronary heart disease patients with myocardial ischemia.
Methods
A total of 96 patients with coronary heart disease,myocardial ischemia treated in our hospital from August 2016 to August 2018 were selected as the research objects.According to the stochastic grouping method,all patients were divided into the control group(48 cases)and observation group (48 cases).Control group was treated by western medicine clinical routine and observation group was treated by western medicine clinical routine and TCM therapy of reinforcing qi and activat blood.The treatment efficiency,ST segment decline frequency and ST segment decline duration were compared between the two groups.
Results
The total effective rate in the observation group was 85.42%,which was significantly higher than that in the control group(72.92%),and the difference was statistically significant(P<0.05).The number of ST segment decline after treatment in the observation group were less than those before treatment,and the duration of ST segment decline were shorter than that before treatment,the differences were statistically significant(P<0.05).The number of ST segment decline after treatment in the observation group was less than that in the control group,and the duration of ST segment decline in the observation group was shorter than that in the control group,the differences were statistically significant(P<0.05).
Conclusion
TCM therapy of reinforcing qi and activat blood has certain clinical effect in the treatment of coronary heart disease patients with myocardial ischemia,can effectively relieve the symptoms of myocardial ischemia.It is worthy of clinical application.
2019 Vol. 26 (7): 183-185 [
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68
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186
Analysis of parasitic infection Results of resident population in Xindu area
ZHONG Fan CHEN Jing▲
[Abstract]
Objective
To analyze the regional characteristics of parasitic infection of resident population in this area,and provide scientific basis for prevention and treatment of intestinal parasitic infection in this area.
Methods
Retrospective analysis from June 2017 to June 2018,the Xindu district resident population in our hospital for stool routine examination of 22 388 cases results.
Results
In 22 388 cases of routine stool examination,three kinds of intestinal worms were detected.Among them,16 cases showed different degree of hemoglobin decline,10 cases of eosinophilgranulocyte percentage and absolute value increased significantly,and 6 cases of fecal occult blood positive.The total infection rate of intestinal parasites was 0.125% (28/22 388),mainly by the infection of the worm(24/28).The infection rates of intestinal parasites in males and females were 0.074%(8/10 853)and 0.173%(20/11 535),and the difference was statistically significant(χ
2
=4.447,P<0.05).The infection rate of each occupational intestinal parasite was 0.000%,0.032%(2/6281),0.141%(10/7089),and 0.201%(16/7954),the infection rates of intestinal parasites in different occupations were compared,and the difference was statistically significant(χ
2
=9.534,P<0.05).The infection rate of intestinal parasites was higher in the 35-65 year old population,which was 0.220%(16/7261),the infection rate was 0.170%(10/5866)more than 65-year-old population,and the infection rate was 0.032% (2/6281)under the age of 7,no other infections in other age groups,the difference in infection between the age groups was statistically significant(χ
2
=14.348，P<0.01).
Conclusion
The infection rate of intestinal parasite inthe resident population of Xindu district is mainly hookworm.Although the infection rate is relatively low,the factors of missed detection cannot be ignored.Effective scientific measures are still needed to publicize and prevent high-risk groups.
2019 Vol. 26 (7): 186-188 [
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50
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189
Investigation on medical staffs′knowledge of safe injection and hand hygiene in a traditional Chinese medicine hospital
LIU Qin； WANG Zuo-yan
Objective
To investigate the awareness of safe injection and hand hygiene of medical staff in a traditional Chinese medicine hospital,and to implement the work program of the Health Bureau,"Blocking the infection of hospital injection and making injection safer" (2015-2018),so as to achieve continuous improvement of safe injection.
Methods
A cluster sampling survey was conducted in March 2017 to investigate 678 medical staff for their knowledge of safe injection and hand hygiene,the accuracy rate was calculated and the scores of different medical departments,professions and professional titles were compared separately.
Results
The correct answer rate of safety injection and hand hygiene was 93.25%,and the score was statistically significant in different departments,professions and professional titles(P<0.05).Nurses′cognition score of safety injection and hand hygiene was higher than that of doctors,and the higher the professional title,the higher the score.
Conclusion
Medical staffs′awareness of safe injection and hand hygiene is different.Hospital managers should grasp the key point of safe injection and conduct personalized and targeted training for different groups and jobs.Continuous training is very important for medical staff to keep safe injection behavior.
2019 Vol. 26 (7): 189-191转196 [
Abstract
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66
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192
Distribution of methylenetetrahydrofolate reductase and methionine synthase reductase gene polymorphisms in women of child-bearing age at Lichuan City,Hubei Province
XU Min JIANG Hong； MOU Dan； MOU Yao-hua； LAN Qiao； HE Ling-yu； QIN Lu； LIU Xin-yu
Objective
To compare the C667T and A1298C loci of methylenetetrahydrofolate reductase (MTHFR)and the methionine synthetase reductase(MTRR)A66G locus among Tujia and Han women of reproductive age in the People′s Hospital of Lichuan City,Enshi Prefecture,Hubei Province.For the case of point polymorphism distribution,the hereditary characteristics of the locus were studied.
Methods
A total of 681 cases of Han and 553 cases of Tujia fertile women were selected as subjects,from those building cards at Lichuan People′s Hospital of Hubei Province from January,2015 to December 2017.Oral epithelial cells were collected to extract genome DNA,Taqman-MGB technology was used to detect MTHFR and MTRR gene polymorphisms,and then compared with those in other nationalities in China.
Results
The gene frequency of MTHFR C677T locus of Tujia women in Lichuan People′s Hospital of Enshi Prefecture,Hubei Province was compared with that of Yanbian Korean,Nanning Zhuang,Ursukazak and Yinchuan Hui women,the differences were statistically significant(P<0.05).The gene frequency at the MTHFR A1298C site was statistically significant compared with that of the Nanning Zhuang and Ursukazak women,the differences were statistically significant(P<0.05).The gene frequency at the MTRR A66G site was compared with that of Ursukazak and Xinjiang Uygur women,and the differences were statistically significant(P<0.05).There was a complete linkage disequilibrium between the two points of MTHFR C677T and A1298C of Tujia in Lichuan City (D′=1.0,r
2
=0.508).There was a complete linkage disequilibrium between two sites of MTHFR C677T and A1298C of Han nationality in Lichuan City (D′=1.0,r
2
=0.424).
Conclusion
There is no significant difference in the polymorphism distribution of MTHFR and MTRR between Tujia and Han populations in Lichuan City,Enshi Prefecture,Hubei Province.However,the above gene distribution in women in the region is region-specific and different from other regions.
2019 Vol. 26 (7): 192-196 [
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60
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197
Intervention effect of post-abortion contraceptive counseling service and follow-up system in women with unwanted pregnancy
WANG Zeng-jie; FENG Wen-xiao; WANG Hong; ZHOU Min
Objective
To evaluate the role of post-abortion contraceptive counseling service and follow-up system after artificial abortion in the implementation of contraceptive measures and the reduction of re-abortion.
Methods
A total of 330 cases who had artificial abortion in the outpatient department of our hospital From January 2015 to December 2016 were selected as study objects.They were provided with post-abortion contraceptive counseling service and follow-up at 1 month,3 months,6 months and 12 months after abortion.The implementation of contraceptive measures and reabortion were investigated.
Results
A total of 330 subjects had a low understanding of contraceptive knowledge,and 231 cases did not take contraceptive measures,contraceptive failure was in 99 cases.After abortion contraceptive counseling services and follow-up,the rate of using contraceptives was high.The 12
th
month follow-up Results showed that intrauterine contraceptive devices was used in 169 cases,subcutaneous implantations was used in 12 cases,oral contraceptives was used in 10 cases,condoms was used in 65 cases,other contraceptives or non-contraceptive was used in 41 cases,31 cases of re-abortion,and 39 cases of total loss of follow-up.
Conclusion
Carrying out post-abortion contraceptive counseling service and follow-up system after abortion can promote implementation of contraceptive measures,and ultimately reduce the risk of re-abortion.
2019 Vol. 26 (7): 197-199 [
Abstract
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65
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200
Investigation and analysis on perioperative antibiotic prophylaxis in 200 orthopedics cases of typeⅠincision
WU Li-sha； HUANG Chun-lan； LIN Xue-feng； LIN Wei-hao
Objective
To understand perioperative antibiotic prophylaxis in orthopedics cases of typeⅠincision in People′s Hospital of Pingshan District in Shenzhen City(hereinafter referred to as “the hospital”),so as to provide a certain reference for the rationalantibiotic prophylaxis in clinic.
Methods
A total of 200 orthopedics cases of typeⅠincision in our hospital from January to September in 2017 were selected randomly,and then were evaluated and analyzed by a retrospective analysis method.
Results
The prophylacticapplication rate of antibiotics in typeⅠincision was 55.50% (111/200).Of the 111 patients with prophylactic antibiotics,the rational rate of antibiotics selection was 84.68%(94/111),the rate of administration before surgery of 0.5-1.0 h was 91.89%(102/111),the rate of incision infection was 18.92%(21/111),patients with prophylactic treatment course≤24 h was 23 cases(25.56%,23/90),>24 h was 67 cases(74.44%,67/90).
Conclusion
The prophylacticapplication rate of antibioticsin orthopedics cases of typeⅠincision in our hospitalthe was relatively high,as well as the rate of treatment course more than 24 h.Supervision and management should be further strengthened to promote the reasonable application of perioperative antibiotic prophylaxis.
2019 Vol. 26 (7): 200-203转207 [
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65
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204
Characteristics of nosocomial infection in ICU ward of our hospital
CHEN Da-yang； GAO Yong-you
Objective
To investigate the status and risk factors of nosocomial infections in Intensive Care Unit(ICU),and to find effective countermeasures for preventing nosocomial infections.
Methods
A total of 206 cases of patients treated in ICU from January 2014 to December 2017 were selected as subjects,and the patients that suffered from nosocomial infections were analyzed by retrospective studies.The incidence,location,pathogenic bacteria and influencing factors of infection were observed.The length of stay and hospitalization expenses of patients with and without nosocomial infection were compared.
Results
Incidence rate of nosocomial infection in ICU was 31.55%,which was significantly higher than that in the whole hospital level(4.29%),and the difference was statistically significant(P<0.05).The average length of hospital stay for patients with nosocomial infections was(40.3±17.1)days,which was longer than that of non-infected patients[(6.5±2.1)d],and the difference was statistically significant(P<0.05).The average hospitalization cost of nosocomial infection patients was(64 379.23±4651.59)yuan,which was significantly higher than that of non-infected patients[(18 245.05±2165.30)yuan],and the difference was statistically significant(P<0.05).The most vulnerable site of nosocomial infections was the lower respiratory tract,which accounted for 58.11%,and patients were mostly infected by Gram-negative bacteria and fungi.Risk factors of nosocomial infections were age(no less than 60 years),long hospitalization time,invasive operation manipulation,massive use of antibiotics and the severe underlying diseases.
Conclusion
The nosocomial infections in ICU should be treated as focal point.Patients with high risk factors should be given early intervening treatment.Comprehensive intervention strategy should be adopted to reduce the incidence rate of nosocomial infections.
2019 Vol. 26 (7): 204-207 [
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79
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208
Application effect of nursing mode based on Omaha system on prognosis and complications of ICU patients with severe respiratory failure
JIANG Hui； YANG Jin-hua； Jiang Ming-yuan； YANG Hong-lian
Objective
To investigate the application effect of Omaha system-based nursing model on the prognosis and complications of ICU patients with severe respiratory failure.
Methods
Seventy patients with ICU severe respiratory failure admitted to Lianhua People′s Hospital from February 2016 to May 2018 were enrolled in the study.They were randomly divided into control group and observation group,35 cases in each group.The control group was received routine ICU nursing.The observation group was received interventions based on the ICU nursing model of Barack Obama-Harvar.Prognosis,ventilator weaning,tatal satisfaction,and rate of complications were compared between the two groups.
Results
The time of ICU stay，hospital stay and mechanical ventilation in the observation group were shorter than those in the control group (P＜0.05）.The success rate and total satisfaction of one-off ventilator withdrawal in the observation group were higher than those in the control group(P＜0.05）.The dependence rate of ventilator in the observation group was lower than that in the control group(P＜0.05）.The incidence of complications such as flatulence,compression injury,dysphoria in oropharynx and tongue,and phlegm obstruction in the observation group were lower than those in the control group,the differences were statistically significant(P＜0.05）.
Conclusion
Using Omaha systembased care mode to care for ICU patients with severe respiratory failure can effectively improve patient prognosis and prevent complications and improve patient satisfaction and ventilator withdrawal success rate.
2019 Vol. 26 (7): 208-210转225 [
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73
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211
Effect of comprehensive nursing measures on delayed recovery after general anesthesia in patients undergoing lobectomy
TU Ping-hua； WANG Qian
Objective
To explore the effect of comprehensive nursing measures on delayed recovery after general anesthesia in patients undergoing lobectomy.
Methods
A total of 120 patients who underwent lobectomy under general anesthesia in our hospital from April 2015 to April 2018 were selected as subjects.According to the random number table method,it was divided into observation group and control group,60 cases in each group.The control group was given routine nursing measures,while the observation group was given comprehensive nursing measures,strictly observing the condition of the disease,maintaining the circulatory and respiratory functions of the patients,ensuring the warmth and rewarming of the patients,and strengthening safety nursing measures.The delayed recovery rate,recovery time and satisfaction degree of the two groups were compared.
Results
After nursing,the delayed recovery rate of the observation group was 5.00%,which was significantly lower than that of the control group(18.33%),the difference was statistically significant(P＜0.05）.The recovery time in the observation group was significantly shorter than that in the control group (P＜0.05）.The satisfaction rate of the observation group was 91.67%,which was significantly higher than that of the control group (56.67%),the difference was statistically significant(P＜0.05）.
Conclusion
Comprehensive nursing measures applied to patients after pulmonary lobectomy after general anesthesia,can effectively reduce the incidence of delayed recovery,shorten the recovery time,and significantly improve patients′satisfaction with nursing work,for patients to safely pass the delayed recovery period has a good effect.
2019 Vol. 26 (7): 211-213 [
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62
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Application effect of self-made shoulder-type ice pack after bromhidrosis surgery
CHEN Xiao-ming； LIU Hua-zhi； CHEN Gao-ping； WEN Qiong
Objective
To explore the application effect of self-made shoulder-type ice pack after bromhidrosis surgery.
Methods
A total of 96 patients with bromhidrosis surgery in our hospital from January 2017 to May 2018 were selected as subjects.The patients were randomly divided into control group (n=48)and observation group (n=48)according to random number table method.The control group was given conventional ice packs,and the observation group was given self-made shoulder-type ice packs.The clinical efficacy and the satisfaction of the two types of ice pack at 2,12 and 24 h after care were compared.
Results
The satisfaction of the observation group at 2,12 and 24 h after cold compress was significantly higher than those of the control group,and the differences were statistically significant(P＜0.05）.The excellent rate of treatment in the observation group was 97.92%(47/48),which was significantly higher than that in the control group (75.00% [36/48]）,the difference was statistically significant （P＜0.05）.
Conclusion
Shoulder-type ice packs can improve patients′outcomes and satisfaction.
2019 Vol. 26 (7): 214-216 [
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60
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217
Application value of seamless nursing mode in stress reaction and bad mood prevention of surgical patients
HUANG Ying-lian； ZHOU Qiu-hong； XIE Shu-zhen
Objective
To explore the application value of seamless nursing mode in the prevention of stress reaction and bad mood in surgical patients.
Methods
84 patients who underwent surgical treatment in our hospital from January 2017 to April 2018 were selected as the research subjects.According to random number table method,it was divided into control group and observation group,42 cases in each group.Patients in the control group were given routine operation room nursing,while the observation group was given seamless nursing on the basis of nursing in the control group.The stress response index (heart rate,diastolic blood pressure,systolic blood pressure and cortisol),HAMA score,HAMD score and nursing satisfaction were observed and compared between the two groups.Results①After nursing,the heart rate,diastolic blood pressure,systolic blood pressure and cortisol stress reaction indexes of the observation group were significantly lower than before nursing and those of the control group (P＜0.05).②the HAMA score and HAMD score of the observation group were significantly lower than before nursing and those of the control group (t=12.375,P＜0.001;t=6.083,P＜0.001);③the nursing satisfaction of the observation group was significantly higher than that of the control group (χ
2
=7.372,P=0.007).
Conclusion
The application of seamless nursing mode in surgical patients has good clinical effect.It is beneficial to relieve the stress response and bad mood of the patients and accelerate the recovery of the patients.It is worthy of clinical application.
2019 Vol. 26 (7): 217-219 [
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60
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220
Clinical effect of Buerger exercise with elastic stocks on edema after lower limb fracture surgery
FENG Wei
Objective
To investigate the clinical effect of Buerger exercise with elastic stocks on edema after lower limb fracture surgery.
Methods
Sixty patients with edema symptoms due to lower extremity fractures treated in our hospital from July 2017 to August 2018 were enrolled and divided into control group and treatment group according to random number table method,30 patients in each group.In the control group,only Buerger exercise was performed after operation,while the patients in the treatment group were treated with elastic stocks for Buerger exercise.The edema control effect,postoperative lower extremity swelling,pain degree visual analog scale (VAS)before and after exercise,edema disappearance time,total postoperative hospital stay,and adverse events were compared between the two groups.
Results
The total effective rate of edema control in the treatment group was significantly higher than that in the control group (P＜0.05）.The lower extremity swelling was significantly lighter in the treatment group than in the control group(P＜0.05）.The disappearance time of edema and total postoperative hospital stay were significantly shorter in the treatment group than in the control group(P＜0.05）.The adverse events were significantly lower in the treatment group than in the control group(P＜0.05）.The pain degree VAS score after exercise in the treatment group was lower than that before exercise,and the intra-group difference was statistically significant(P＜0.05）.The pain degree VAS score after exercise in the control group was lower than that before exercise,and the intra-group difference was statistically significant(P＜0.05）.There was no significant difference between the two groups before treatment as to the VAS score (P＞0.05）,while the difference after treatment was significant(P＞0.05）.
Conclusion
In patients with lower extremity fractures with edema symptoms,the use of elastic stocks for Buerger exercise treatment can reduce the degree of swelling,control pain and reduce adverse events in a short period of time,thereby shortening the hospitalization time and improving the treatment effect of the disease.
2019 Vol. 26 (7): 220-222 [
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71
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223
Application effect of uterine artery embolization combined with whole course quality nursing in emergency obstetric and gynecological hemorrhage patients
LIAO Yan
Objective
To explore the effect of uterine artery embolization （UAE） combined with whole-course highquality nursing in patients with emergency obstetric and gynecological bleeding.
Methods
A total of 60 emergency patients with hemorrhage admitted to Department of Gynecology and Obstetrics in our hospital from March 2013 to November 2018 were selected as the research objects.They were divided into control group (30 cases)and observation group (30 cases)according to random number table method.The control group was treated with conservative treatment and routine nursing,while the observation group was treated with UAE and whole course quality nursing.Relevant observation indexes and clinical outcome of two groups after treatment were compared.
Results
The fever time and vaginal bleeding time in the observation group were significantly shorter than those in the control group,with statistical significance (P＜0.05）;the hysterectomy rate in the observation group was significantly lower than that in the control group,and the complete hemostasis rate was significantly higher than that in the control group,with statistical significance (P＜0.05）.
Conclusion
Bilateral UAE via femoral artery puncture and intubation is effective in the treatment of emergency obstetric and gynecological hemorrhage,which can effectively stop bleeding,shorten the time of vaginal bleeding,and strengthen the related nursing work,and improve the prognosis level.
2019 Vol. 26 (7): 223-225 [
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68
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226
Nursing effect of traditional Chinese medicine on senile vertigo
CAO Huan-huan ； YU Ping
Objective
To analyze the effect of traditional Chinese medicine (TCM)nursing on vertigo in the elderly.
Methods
A total of 120 elderly patients with vertigo treated in our hospital from January 2016 to August 2017 were selected.According to the odd/even number,they were divided into control group (odd number)and observation group(even number),60 cases in each group.The control group was given regular nursing and the observation group was used TCM nursing,the occurrence rate of vertigo and quality of life in the two groups were compared.
Results
The incidence of vertigo in the observation group was 1.67%.There was no recurrence of vertigo during the follow-up of 6 months.The incidence of vertigo in the control group was 13.33%,and the recurrence rate of vertigo was 11.67%,the differences were statistically significant(P<0.05）.The body condition score,psychological function score and social function score were all higher compared with those of the control group with statistical significance(P＜0.05）.
Conclusion
The elderly patients with vertigo can improve patients′condition through TCM nursing with pattern identification,reduce the frequency of vertigo,and ameliorate the quality of life with a remarkable nursing effect.
2019 Vol. 26 (7): 226-228 [
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74
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Application of high-quality nursing measures in thoracoscopic esophagectomy for esophageal cancer
XUE Xia-ping； Miao Li
Objective
To investigate the operation and nursing measures of operating room for thoracoscopic esophageal cancer radical resection.
Methods
One hundred patients with thoracoscopic esophageal cancer who underwent surgery from August 2016 to January 2818 in our hospital were selected and divided into the control group and the observation group according to random number table method,50 cases in each group.The control group was treated with routine nursing.On the basis of routine nursing,the observation group was intervened by high quality nursing measures.The anxiety and depression status(SAS）score,nursing satisfaction,and quality of life(SF-36)score of the two groups of patients before and after treatment were compared.
Results
SAS scores after nursing in both groups were significantly lower than those before nursing,the SAS score of the observation group was significantly lower than that of the control group (P<0.05）.The nursing satisfaction of the control group was 60%,the nursing satisfaction of the observation group was 96%,and the nursing satisfaction of the observation group was higherthan that in the control group （P＜0.05）.The SF-36 score of the two groups after nursing was significantly higher than that before nursing (P＜0.05).The SF-36 score of observation group was significantly higher than that of control group after nursing,the difference was statistically significant （P＜0.05）.
Conclusion
Active and effective operation room nursing combined with thoracoscopic esophageal cancer radical surgery can improve the curative effect,relieve the depression and anxiety of patients,improve the postoperative quality of life,and improve the care of patients and their families.Satisfaction,paving the way for a good relationship between nurses and patients,is worth promoting.
2019 Vol. 26 (7): 229-231 [
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70
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Effect of cluster nursing on prevention of complications of breast cancer infusion port
TAN Hui-yi； ZHU Qing-mei； YAN Chan-juan； CHEN Rong-xia
Objective
To study the effect of cluster nursing on preventing complications of breast cancer infusion port.
Methods
A total of 1100 breast cancer patients treated in our hospital from January 2013 to June 2018 were selected and divided into study group (550 cases)and control group (550 cases)with reference lottery plus patient admission time.Patients in the control group were received routine nursing,while patients in the study group were received cluster nursing on the basis of routine nursing,the complication rate,quality of life score and nursing satisfaction of the two groups were compared.
Results
The total complication rate in the study group was 8.18%,and that in the control group was 45.63%.compared with the corresponding data,the difference between the two groups was statistically significant(P＜0.05）.The quality of life scores of patients in the study group were higher than those in the control group in physical function， role function， emotional function,cognitive function and social function.the differences were statistically significant(P＜0.05）.The nursing satisfaction of the patients in the study group was 95.64%,and that of the patients in the control group was 68.54%.the difference was statistically significant(P<0.05）.
Conclusion
During the treatment of breast cancer patients at the infusion port,cluster nursing can not only reduce the probability of complications,optimize the quality of life of patients,but also improve the satisfaction of patients with nursing and promote the further harmonious development of nurse-patient relationship.
2019 Vol. 26 (7): 232-234 [
Abstract
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Effect of diabetes mellitus nursing clinic on health education for operative patients
ZHAO Xue-ying； XU Dan； JIANG Ping； XU Yang； LI Jiao； ZHANG Dong-mei； ZHA Ling
Objective
To explore the effect of diabetes mellitus(DM)nursing clinic on health education for operative patients.
Methods
A total of 184 DM patients undergone surgery admitted to our hospital from June 2016 to June 2017 were enrolled in the study.They were divided into control group and observation group according to the random number table method,92 cases in each group.In the control group,health education in regular clinic was implemented,while in the observation group,health education was implemented at the DM specialist clinic.The blood glucose index,treatment compliance,health knowledge mastery,and adverse events were compared between the two groups at discharge and one year follow-up.
Results
The blood glucose levels including fasting blood glucose(FBG),postprandial 2 h blood glucose(2 h PG),and glycated hemoglobin(HbA1c)in the two groups were lower than those at discharge(P＜0.05）.The blood glucose indices including FBG,2 h PG,and HbA1c in the observation group were lower than those in the control group one year follow-up after surgery(P＜0.05）.The patients′treatment compliance including rational diet,exercise therapy,on-time medication,disease monitoring,and regular review,and health knowledge mastery including disease knowledge mastery degree,medication mastery,and knowledge on disposal of adverse events in the observation group were all higher than those in the control group (P＜0.05）.The total incidence of adverse events was lower in the observation group than in the control group,the difference was statistically significant(P<0.05）.
Conclusion
The DM nursing specialist clinic can improve the health education effect in DM patients undergone surgery and it is worthy of clinical promotion.
2019 Vol. 26 (7): 235-237 [
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70
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238
Application of chronic disease self-management program in nursing care of patients with chronic kidney disease
WAN Yu-hong； YI Na； WANG Xue-jiao
Objective
To explore application effect of chronic disease self-management program(CDSMP)in patients with chronic kidney disease(CKD).
Methods
A total of 110 patients with CKD treated in our hospital from June 2016 to June 2017 were selected and according to the number of admission time,the patients were divided into control group and study group.The control group was given routine nursing,while the study group was given CDSMP on the basis of the control group.The differences in health behaviors,health status and self-management ability between the two groups before and after intervention were compared.
Results
The scores of exercise and communication with physicians of study group were significantly higher than pre-intervention and control groups,and the scores of emotional management,social function,energy and self-management ability were significantly lower than those in the pre-intervention and control groups,the differences were statistically significant(P<0.05）.
Conclusion
CDSMP is helpful to improve the ability of self-managemen,health behavior and health status of patients with CKD,which is worthy of clinical application.
2019 Vol. 26 (7): 238-240 [
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68
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241
Application effects of collaborative nursing in functional rehabilitation of patients with dysphagia after stroke
CHEN Yu-fang； LIU Zhi-yan； CAO Lu-yang； LIAO Yu-ping
Objective
To explore the effect of collaborative nursing on functional rehabilitation of patients with dysphagia after stroke.
Methods
From January 2015 to June 2017,78 patients with dysphagia after stroke treated in our hospital were selected and divided into cooperation nursing group (39 cases)and control group (39 cases)according to random number table method.Patients in the control group were given routine nursing,and patients in the synergistic nursing group were given health education,skill counseling and group cooperation.The clinical efficacy,Watian drinking water score,quality of life score,treatment satisfaction score and the incidence of pneumonia were observed.
Results
The effective rate of the cooperative nursing group was significantly higher than that of the control group (P＜0.05）.After the intervention,the scores of Watian drinking water test in the two groups were significantly reduced,and the score of Watian drinking water test in the collaborative nursing group was significantly lower than that in the control group (P＜0.05）.After the intervention,the scores of quality of life in the two groups were significantly increased,and the score of quality of life in the cooperative nursing group was significantly higher than that in the control group(P＜0.05）.After the intervention,the scores of satisfaction with treatment in the cooperative nursing group were significantly higher than those in the control group (P＜0.05）,and the incidence of pneumonia in the cooperative nursing group was significantly lower than that in the control group(P＜0.05）.Conclusions Collaborative nursing model can effectively improve the swallowing dysfunction of stroke patients,improve the quality of life,reduce the incidence of aspiration pneumonia,and improve the treatment satisfaction of patients,which is worthy of further promotion.
2019 Vol. 26 (7): 241-244 [
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60
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245
Effect of clinical nursing pathway on anxiety and depression in patients with panic disorder
HUANG Xia； SONG Xiu-jin； HUANG Jia-yao
Objective
To explore the effect of clinical nursing pathway on anxiety and depression in patients with panic disorder.
Methods
From December 2015 to December 2016,78 patients with panic disorder in our hospital were selected and divided into control group and observation group according to different nursing methods,39 cases in each group.The control group was treated with routine nursing，the observation group was treated with clinical path management mode，the effect of nursing,the improvement of anxiety and depression,and the total satisfaction of nursing were compared between the two groups.
Results
The observation group treatment effective rate was 92.31%,significantly higher than the 74.36%in the control group,the difference was statistically significant(P＜0.05）.The scores of Hamilton Anxiety Scale (HAMA)and Hamilton Depression Scale (HAMD)in the observation group were significantly lower than those in the control group after nursing care (P＜0.05）.The total nursing satisfaction observation group was obviously higher than that of control group,the difference was statistically significant(P＜0.05）.
Conclusion
Clinical nursing path of anxiety and depression in patients with panic disorder to improve the effect is remarkable,can improve the treatment effect,improving the quality of nursing,rehabilitation of the patients with positive clinical significance.
2019 Vol. 26 (7): 245-247 [
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75
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Clinical effect of cluster nursing intervention in resuscitation of neonatal asphyxia in cesarean section
YUAN Shu-ping； WEI Ting； LIU Xiao-ping
Objective
To explore the effect of cluster nursing intervention on resuscitation of neonates with asphyxia after cesarean section.
Methods
A total of 90 neonates with postpartum asphyxia after cesarean section in our hospital from November 2016 to November 2017 were selected as subjects.A total of 45 asphyxia neonates delivered from November 2016 to May 2017 were the control group(routine care),and 45 asphyxiated neonates delivered from June to November 2017 were selected as the experimental group (cluster nursing intervention was given on the basis of routine nursing).The 1,5 min Apgar scores,5,10 min resuscitation success rates and family satisfaction were compared between the two groups.
Results
There was no significant difference in the 1 min Apgar scores between two groups(P＞0.05）,while 5 min Apgar score of the experimental group was higher than that of control group,the difference was significant(P＜0.05）.The success rate of 5 min resuscitation in the experimental group was higher than that in the control group,the difference was significant(P＜0.05）,while there was no difference in 10 min resuscitation between the two groups(P＞0.05）.The satisfaction degree of the parents of the newborns in the experimental group was higher than that in the control group,the difference was significant(P＜0.05）.Conclusions Cluster nursing intervention in the cesarean section neonatal asphyxia resuscitation can improve resuscitation effect and has great significance for rescuing the life of asphyxiated neonates,as well as improve parents′satisfaction with nursing.
2019 Vol. 26 (7): 248-250 [
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71
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Application effect of psychological nursing and corresponding nursing measures of cephalopelvic disproportion in parturient women during trial delivery
WEI Hai-rong
Objective
To explore the psychological nursing and the corresponding nursing measures of cephalopelvic disproportion in parturient women during trial delivery.
Methods
From January 2012 to January 2016,100 cases of parturients admitted to our hospital with unknown cephalopelvic disproportion during the trial labor were selected as the research objects.All of them were divided into control group and observation group according to random number method,50 cases in each group.The control group was treated with conventional nursing,the observation group was treated with conventional nursing and corresponding nursing measures.The duration of labor,postpartum blood loss,success rate of trial labor and cesarean section were compared between the two groups.
Results
The duration of labor in the observation group was shorter than that in the control group,the natural delivery rate of patients in the observation group was significantly higher than that in the control group,and the postpartum blood loss was significantly lower than that in the control group,the differences were statistically significant(P＜0.05）.
Conclusion
Through understanding the occurrence of cephalopelvic disproportion in trial birth,finding out the reason,giving psychological nursing and corresponding nursing measures,cephalopelvic disproportion is significantly improved,effectively shorten the duration of labor,reduce postpartum blood loss,improve the rate of natural birth,greatly reduce the rate of cesarean section.
2019 Vol. 26 (7): 251-253 [
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