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Effect and safety observation of endoscopic retrograde cholangiopancreatography in the treatment of elderly patients with single choledocholithiasis |
CHEN Wen-zhe |
Department of Hepatobiliary Surgery,the Sixth Hospital Affiliated of Guangzhou Medical University,Guangdong Province,Guangzhou 511518,China |
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Abstract [Abstract]Objective To explore the effect and safety of endoscopic retrograde cholangiopancreatography (ERCP)in the treatment of elderly patients with single choledocholithiasis.Methods Sixty elderly patients with single choledocholithiasis admitted to our hospital from March 2013 to July 2017 were selected as the study subjects,they were divided into observation group and control group by random number table method,with 30 cases in each group.The observation group was treated with ERCP lithotripsy,while the control group was treated with Laparoscopic Choledocholithotomy.The general conditions of perioperative period(exhaust time,visual analogue scale[VAS]score,hospitalization time),stone removal effect(residual stone rate,recurrence rate of 6 months)were compared between the two groups,and the preoperative and postoperative 1W were evaluated.The levels of liver function(ALT,AST and GGT)were recorded and compared between the two groups.Results The exhaust time and hospitalization time in the observation group were shorter than those in the control group(P<0.05),postoperative VAS score was lower than that of control group(P<0.05).There was no significant difference in residual stone rate and recurrence rate of 6 months between the two groups(P>0.05).The levels of ALT,AST and GGT in the two groups were lower than those before operation at one week after operation (P<0.05),the levels of ALT,AST and GGT in the observation group one week after operation were lower than those in the control group (P<0.05).There was no significant difference in the total incidence of postoperative complications between the two groups(P>0.05).Conclusion ERCP lithotripsy is similar to laparoscopic choledocholithotomy in the treatment of single choledocholithiasis,but the former is more advantageous in improving perioperative conditions and promoting the recovery of liver function indicators.
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