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2017 Vol. 24, No. 35
Published: 2017-12-18
4
Clinical study of flexible ureteroscope lithotripsy by intelligent pressure control treating renal calculus
PENG Guang-hua；DU Chuan-ce；ZHONG Jiu-qing；LIU Tai-rong；PENG Zuo-feng ；SONG Le-ming
ObjectiveTo explore the clinical effect of flexible uretroscopy lithotripsy treating renal calculus with or without pressure suction.MethodsPatented measurable pressure of the renal pelvis ureteroscopic attraction sheath(abbreviated as pressure measuring sheath)and intraluminal perfusion pressure monitoring and control platform(abbreviated platform)equipment was compared with traditional ureteroscopic sheath.Clinical data of 96 patients with renal calculus (diameter＜2 cm)treated in our department from January 2016 to March 2017 was analyzed and compared.Among tnem,group A(n=48)and group B(n=48)was given the platform monitoring and regulating renal pelvic cavity irrigation pressure with suctioning sheath and traditional sheath without pressure suction respectively.The related indexes before and after operation were compared in patients between the two groups.ResultsThe operation time in group A was shorter than that in group B,and the stone clearance rate was significantly higher than that of group B,and the difference was statistically significant(P＜0.05).Before operation,serum procalcitonin(PCT)and endotoxin(ET)between the two groups were not statistically significant difference(P＞0.05),after operation,there was a statistical difference of PCT and ET level within 24 hours between the two groups(P＜0.05).ConclusionFlexible ureteroscopy lithotripsy applied to the patented platform monitoring and regulating renal pelvic cavity irrigation pressure with suctioning sheath has the obvious effect and a significant advantage of preventing the high pressure of renal pelvis and increasing the percentage of clearance rate.
2017 Vol. 24 (35): 4-7 [
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Clinical effect of laparoscope treating adult urachal fistula
LIU Hong-fu；ZENG Xiang-fu；ZHANG Lei；DENG Wei
ObjectiveTo investigate the clinical effect of laparoscope treating adult urachal fistula.MethodsFrom January 2011 to May 2017,30 adults with urachal fistula treated in the First Affiliated Hospital of Gannan Medical College were selected and they were randomly divided into the experimental group(n=15)and control group(n=15).The experimental group was given laparoscopic resection of urachus,whilde the control group was given open UF resection.ResultsThe operation time in the experimental group was(35.4±4.2)min,which was significantly shorter than that in the control group[(56.1±6.2)min],and the time to be off bed after surgery in the experimental group was(1.20±0.52)d,which was significantly shorter than that in the control group[(2.50±0.64)d],and the complete recovery time was(4.30±0.84)d in the experimental group,which was significantly shorter than that in the control group[(10.50±1.32)d)(P＜0.05).The intraoperative amount of bleeding in the experimental group was(6.2±00.54)ml,which was fewer than that in the control group[(25.60±3.45)ml],and the total effective rate of the experimental group (100.00%)was higher than that of the control group(66.67%),and the incision infection rate in the experimental group was 0,which was lower than that of the control group(33.33%)(P＜0.05).ConclusionLaparoscopic surgery treating UF has the advantages of short operation time,fast recovery,few bleeding,low incision infection rate,and high therapeutic effective rate,which is worthy of extensive promotion in clinic.
2017 Vol. 24 (35): 8-11 [
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Clinical effect of Jinghua Weikang Gelatin Pearls combined with quadruple therapy in the treatment of peptic ulcer complicated with Hp infection
GU Jing； ZHANG Guo-bao ；GENG Chang-hai
ObjectiveTo investigate the clinical effect of Jinghua Weikang Gelatin Pearls combined with quadruple therapy in the treatment of peptic ulcer complicated with Helicobacter pylori(Hp)infection.Methods123 patients with peptic ulcer complicated with Hp infection treated in our outpatient clinic and inpatient wards from August 2014 to May 2017 were divided into the three groups using the complete random method.In the control group A,regimen of standard quadruple therapy was used for 14 days.In the experimental group B,the standard quadruple therapy was continued for 14 days,and Jinghua Weikang Gelatin Pearls was used for another 18 days.In the experimental group C,Jinghua Weikang Gelatin Pearls was firstly used for 18 days,followed by 14-day standard quadruple therapy.Hp eradication rate,clinical symptomatic improvement,and ulcer healing under endoscope were calculated and analyzed among three groups.ResultsThe total effective rate of patients in the experimental group B and C was significantly higher than that in the control group A,and the difference was statistically significant(P＜0.05),the total effective rate in the experimental group C was higher than that in the experimental group B,with a statistically significant difference (P＜0.05).In control group A,Hp eradication rate of the control A was 63.41%,and it was 85.37%in the experimental group B,and it was 87.80%in the experimental group C,and Hp eradication rate of patients in the experimental group B and C was significantly higher than that in the control group A,and the difference was statistically significant(P＜0.05),and there was no statistical difference of Hp eradication rate between the experimental group B and C(P＞0.05).There was no significant difference of ulcer healing under endoscope among the three groups(P＞0.05).ConclusionHp eradication rate and the role of improving the clinical symptoms in patients of Jinghua Weikang Gelatin Pearls combined with quadruple therapy obtain more remarkable effect compared with only quadruple therapy.Jinghua Weikang Gelatin Pearls followed by quadruple therapy is more beneficial of improving clinical symptoms.
2017 Vol. 24 (35): 12-14 [
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216
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15
Effect comparison of three-dimensional conformal radiotherapy and intensity-modulated radiotherapy for after invasive thymoma operation
HUANG Yu-ting；ZHU Ming；ZOU Wen-hui
ObjectiveTo compare the difference of pulmonary dosimetry and the incidence of radiation-induced lung injury in patients with invasive thymoma after three-dimensional conformal radiotherapy(3D-CRT)and intensity-modulated radiotherapy (IMRT)operation.MethodsFrom January 2014 to June 2016,28 patients with invasive thymoma treated in Huizhou Central People′s Hospital in Guangdong Province were selected and they were randomly divided into 3D-CRT group(n=14)and IMRT group(n=14).After surgery,radiotherapy was necessary.They were provided with 3DCRT and IMRT separately in the two groups.Plan of 3D-CRT and IMRT were designed for every patient and pulmonary dosimetry in two-radiotherapy plans was compared.They were all followed up,and the incidence of radiation-induced lung injury was also compared between the two groups.ResultsThe lung V5was(65.68±11.32)%in IMRT group,which was higher than that in 3D-CRT group[(57.17±9.46)%](P＜ 0.05).The lung V10,V20,and V30in IMRT group was(45.78±10.00)%,(23.19±7.12)%,and(13.40±5.15)%respectively,which was lower than that in 3D-CRT group[(47.70±9.48)%,(26.54±7.76)%,and(15.10±4.90)%accordingly](P＜0.05).During the follow-up,there were two cases occurred with radiation-induced lung injury in IMRT group,one in the 3D-CRT group,which was not displayed significant difference about the incidence of radiation-induced lung injury(P＞0.05).ConclusionPostoperative IMRT for invasive thymoma,the radioactive volume in low-dose area of the lung is larger than 3D-CRT,but in 10 Gy,20 Gy,and 30 Gy the radioactive lung area is smaller in comparison with that by 3D-CRT,which indicates the protection of lung is better when the dosage is higher.
2017 Vol. 24 (35): 15-18 [
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Clinical features analysis of patients with reflux esophagitis with abnormal gastroesophageal flap valve
HENG Ding ；YE Bi-xing ；LIN Lin
ObjectiveTo analyze the clinical features of patients with reflux esophagitis(RE)with abnormal gastroesophageal flap valve(GEFV)to provide the reference for the diagnosis and treatment of reflux esophagitis.MethodsPatients with RE given gastroscopy in gastroenterology department of our hospital from July 2011 to April 2012 were collected and they were divided into GEFV normal group(gradeⅠandⅡof GEFV,n=229)and GEFV abnormal group(gradeⅢandⅣof GEFV,n=103).Patients were followed-up by questionnaire survey and after proton pump inhibitor(PPI)treatment,the degree of esophagitis(LA standard),hiatal hernia(HH),Hp positive rate,age,gender,BMI,diet and lifestyle,clinical symptoms,quality of life,anxiety and depression score,the efficacy of Omeprazole and so on in patients between the two groups were compared.ResultsThe proportion of male patients in GEFV abnormal group was higher than that in GEFV normal group(P＜0.05).Cmpared with GEFV normal group,the proportion of smoking and drinking increased significantly,the proportion of HH and severe esophagitis were high,the degree of acid reflux,stomach burning sensation symptom were more severe,and the efficacy of Omeprazole was poorer.poor curative effect of omeprazole (P＜0.05).There was no statistical difference of age,BMI,Hp positive rate,quality of life and anxiety and depression score between the two groups(P＞0.05).ConclusionThe prevalence rate of severe esophagitis and HH are significantly are significantly increased,the reflux symptoms are more severe,and PPI has poor curative effect.Bad habits such as smoking and drinking may be associated with GEFV abnormalities.
2017 Vol. 24 (35): 19-22 [
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Study progress in anesthetic-induced neurotoxicity in developing brains
XIAO Hua-ping；YANG Xiao-min
Anesthetic-induced neurotoxicity in developing brains has attracted extensive attention.There is no evidence that the results of animal experiments are relevant to the clinic,but researches data have shown that transient impairment of nerve function can be caused by exposure to certain anesthetics,which can affect the development of the brain.In this paper,the neurotoxicity mechanism,animal experiment,clinical research and current debate on anesthetics are discussed.It is advised not to undergo surgery during brain development.Multiple anesthetics should be avoided in pediatric anesthesia.
2017 Vol. 24 (35): 23-26 [
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189
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Prognostic effect of percutaneous catheterization on acute pancreatitis with necrotic infection
LIU Jin-cai
ObjectiveTo observe the prognostic effect of percutaneous catheter drainage in the treatment of acute pancreatitis with necrotic infection.Methods40 patients with necrotizing necrosis and acute necrotizing pancreatitis who were admitted to our hospital from May 2014 to May 2017 were randomly divided into control group and observation group,20 cases in each group.Control group was given conservative treatment,observation group was treated percutaneous catheter drainage.The clinical indexes and complication of the two groups were compared.ResultsThe treatment time,hospitalization time of observation group with acute pancreatitis and necrotic infection were shorter than that of control group,and hospitalization expense was less than that of control group(P＜0.05).The incidence of complications in the observation group was 5.00%,which was lower than that in the control group(35.00%),the difference was statistically significant(P＜0.05).ConclusionPercutaneous puncture and catheter drainage in patients with acute pancreatitis and necrotic infection can effectively improve the prognosis of patients with high safety and promote the early recovery of patients,worthy of clinical application.
2017 Vol. 24 (35): 27-28转40 [
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Application of transparent cap in removal of foreign body in upper digestive tract
LIU Shu-na ；LI Xing
ObjectiveTo treat the patients diagnosed as upper gastrointestinal foreign bodies through the transparent cap assisted gastroscopy and analyze the application effect of the method.Methods72 patients diagnosed as upper gastrointestinal tract were selected from January 2016 to May 2017 in our hospital and divided into two groups according to random number method,36 in experimental group and 36 in control group.In the experimental group,foreign bodies were removed by the transparent cap assisted gastroscopy.The control group was treated by direct gastroscopy to remove the foreign body.The time and amount of foreign body removal were compared between the two groups.ResultsThe success rate of foreign body removal in experimental group was significantly higher than that in control group,and the average operation time was significantly shorter than that in control group,the differences were statistically significant(P＜0.05).ConclusionFor patients with upper gastrointestinal tract foreign bodies，the use of transparent cap assisted gastroscopy for foreign body removal,the treatment effect is quite significant,the program worthy of promotion in clinical use.
2017 Vol. 24 (35): 29-31 [
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205
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Observe the clinical effect of the treatment of severe hepatitis with Magnesium Isoglycyrrhizinate Injection
ZHU Xiao-feng
ObjectiveTo investigate the clinical effect of the application of Magnesium Isoglycyrrhizinate Injection in patients with severe hepatitis treatment.MethodsFrom May 2016 to May 2017 124 cases of severe hepatitis patients treated in our hospital were selected as the research objects.They were randomly divided into study group and control group,62 patients in each group.The control group was given nucleoside antiviral drugs,nutritional support,treatment and intravenous fluid therapy,the study group on the basis of conventional treatment was given Magnesium Isoglycyrrhizinate Injection for intravenous drip.The clinical efficacy of the two groups and the changes of liver function indexes before and after treatment were observed and compared.ResultsThe effective rate of treatment in the study group was 85.48%,which was significantly higher than that of the reference group (70.97%),and the difference was statistically significant(P＜0.05).The liver function indexes such as ALT,AST,TBIL and so on were not significantly different between the two groups before treatment.The recovery of liver function indexes of the study group was significantly better than that of the reference group after treatment,the differences were statistically significant(P＜0.05).ConclusionThe treatment of severe hepatitis patients with Magnesium Isoglycyrrhizinate Injection on the basis of conventional treatment is effective,can effectively improve liver function injury,and high safety,worthy of further clinical application.
2017 Vol. 24 (35): 32-34 [
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Effect of Levothyroxine Sodium Tablets in the treatment of subclinical hypothyroidism during pregnancy
GUAN Xiao-ling
ObjectiveTo explore the clinical effect of Levothyroxine Sodium Tablets in the treatment of subclinical hypothyroidism during pregnancy.MethodsFrom January 2016 to June 2017,70 pregnant women definitely diagnosed as subclinical hypothyroidism in our hospital were enrolled.According to acceptance of drug medication or not，they were evenly divided into treatment group and control group.In the treatment group,Levothyroxine Sodium Tablets was used,while no drug medication in the control group.The changes of thyroid function,pregnancy outcome,and the situation of newborns were observed in the two groups.ResultsThe thyroid function in the treatment group was significantly better than that before treatment,and that in the control group with statistical differences(P＜0.05).The pregnant outcome and neonatal situation in the treatment group were significantly superior to those in the control group with statistical significance (P＜0.05).ConclusionClinical application of Levothyroxine Sodium Tablets in the treatment of subclinical hypothyroidism during gestation can obtain a great effect by markedly improving the thyroid function of pregnant women,pregnancy outcome,and quality of life of newborns.
2017 Vol. 24 (35): 35-37 [
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Effect of pre-hospital emergency treatment on prognosis of cerebral hemorrhage
CAI Rong；WAN Yu-hua；QUAN Song-mei；XU Xiang
ObjectiveTo explore the prognosis of patients with cerebral hemorrhage before treatment.MethodsA total of 60 patients with cerebral hemorrhage who were treated in our hospital the emergency center from February 2016 to April 2017 were selected as the subjects,and the patients were divided into observation group and experimental group,30 cases in each group.The patients in the control group
received
first aid treatment in the hospital.After receiving the first aid treatment,the patients in the experimental group received the first aid treatment in the hospital.The treatment effect,the occurrence probability of the complication and the neurological defect were compared between the two groups.ResultsAfter treatment,the effective rate(83.33%)was significantly higher in the experimental group than that in the control group(50.00%).The complication rate(33.34%)in the experimental group was significantly lower than that in the control group(50.00%),the difference between the two groups was statistically significant(P＜0.05).The neurological function score[(31.98±5.67)points]in the experimental group was significantly higher than that in the control group[(20.94±2.64)points],which was statistically significant.ConclusionIntracerebral hemorrhage in patients with pre-hospital treatment can significantly improve the prognosis of the effect,especially for reducing the mortality rate of patients,the incidence of complications and brain function neurological deficits have a significant effect,it is worth further hospital emergency measures to improve promotion.
2017 Vol. 24 (35): 38-40 [
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The role of head and neck training in improving the balance of hemiplegic patients and the recovery of lower limb motor function
JIANG Xing-mei；ZHUANG Xiao-peng；ZHANG Wei
ObjectiveTo explore the effect of head and neck training in promoting balance of hemiplegia and recovery of lower limb motor function.Methods76 patients with stroke hemiplegia admitted in our hospital from July 2015 to September 2016 were randomly divided into trial group and control group according to the random number table method.The rats in the control group were given routine rehabilitation training based on Bobath technique.The head neck training was trained on the basis of routine rehabilitation training in the trial group.After 4 weeks of treatment,the Fugl-Meyer lower limb motor function rating scale(FMA),Bery balance scale(BBS),Tinetti gait assessment scale(TGA)and 10 m walking speed were used to evaluate the balance of the two groups and the recovery of lower limb motor function.ResultsThe balance and motor function of the two groups were significantly improved compared with those before recorery treatment(P＜0.05）.The FMA scale,BBS scale,TGA scale and 10 m walking speed score were compared with the control group,the difference was statistically significant(P＜0.05）.ConclusionIncreasing head and neck training on the basis of routine rehabilitation training is of great significance to promote the balance of hemiplegic patients and the recovery of motor function of lower extremities.It can be more effective in improving the quality of life of patients and deserves clinical promotion.
2017 Vol. 24 (35): 41-43 [
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Expression of CD44v6 and PCNA in gastric carcinoma and its relationship with prognosis of gastric
YU Zhi-long ；LIU Qi-fang ；XIONG Long-xin▲
ObjectiveTo investigate the expression of CD44v6 and PCNA in gastric carcinoma and its relationship with the prognosis of gastric cancer.Methods80 cases with gastric cancer treated in the Third Affiliated Hospital of Nanchang University from January 2008 to December 2012 were selected as subjects and divided into observation group and control group according to the random numbers table method,40 cases in each group.The patients in the observation group were used surgical treatment under the guidance of CD44v6 and PCNA expression level examination.The control group was treated with routine operation,mainly in the clinical experience,preoperative imaging examination and intraoperative findings.The positive scores of CD44v6 in cancer tissues,adjacent tissues of cancer and surgical margin were compared between the two groups.The level of PCNA expression in cancer tissues,adjacent tissues and surgical margin were compared between the two groups.The surgical excision effect was compared between the two groups.ResultsThe positive scores of CD44v6 and level of PCNA expression in cancer tissues were compared,and the difference was not statistically significant(P＞0.05).While the positive scores of CD44v6 and level of PCNA expression in adjacent tissues and surgical margin in the observation group were significantly lower than those in the control group,and the differences were statistically significant(P＜0.05).The resection rate of R0 in observation group was 97.5%,which was significantly higher than that in the control group,and the difference was statistically significant(P＜0.05).ConclusionThe positive rate of CD44v6 and the expression of PCNA in gastric cancer patients can be used to guide the operation and improve the pathologic resection rate.
2017 Vol. 24 (35): 44-46 [
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Clinical effect of hypedractionated accelerated radiotherapy combined with EP chemotherapy regimen in treatment of limited-stage small cell lung cancer
JIANG Bi-feng； LIN Hua-ming
ObjectiveTo investigate the clinical effect of hypedractionated accelerated radiotherapy(HART)combined with EP chemotherapy regimen in treatment of limited-stage small cell lung cancer(LS-SCLC).Methods50 patients of LS-SCLC treated in our hospital from January to December 2014 were selected as subjects,and they were divided into observation group and control group by random number table method,with 25 cases in each group.Control group was given three dimensional conformal radiation therapy and standard EP chemotherapy regimen,while observation group was given intensity modulated radiation therapy and standard EP chemotherapy regimen.After treatment for two months,the total treatment effective rate,progression-free survival,overall survival,two-year survival rate and safety were compared between the two groups.ResultsThe total treatment effective rate of observation group was higher than that of control group,and the difference was statistically significant(P＜0.05).The progression-free survival,overall survival in observation group were longer than those in control group,and the differences were statistically significant(P＜0.05).The two-year survival rate of observation group was 80.00%,which was higher than 52.00%of control group,and the difference was statistically significant(P＜0.05).The incidence of adverse reactions were compared between the two groups,and the difference was not statistically significan(P＞0.05).ConclusionHART combined with EP chemotherapy regimen in treatment of LS-SCLC can increase short-term efficacy,prolong survival time of patients and not add toxic-side effects,which is a safe and efficient treatment regimen.
2017 Vol. 24 (35): 47-49 [
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Metronomic chemotherapy effect of Capecitabine combined with Thalidomide in the chemotherapy of advanced colorectal cance
CHEN Zhi
ObjectiveTo investigate the clinical effect of Capecitabine combined with Thalidomide in the metronomic chemotherapy of advanced colorectal cancer.MethodsFrom February 2016 to March 2016,56 patients who diagnosed with advanced colorectal cancer treated in our hospital were selected as the research objects,and they were divided into the combination group(n=30)and chemotherapy group(n=26)according to random number table method.The combination group were treated with Capecitabine combined with Thalidomide.In the chemotherapy group,Oxaliplatin was injected intravenously on the first day and Leucovorin was injected intravenous from second to fifth days,and 20 days for one cycle.The effects of chemotherapy,therapeutic effect and adverse reactions were compared between the two groups.ResultsThe disease control rate of the patients in the combination group was 76.67%,and in the chemotherapy group was 53.85%,the control rate of the disease was compared between the two groups,and the difference was statistically significant(P＜0.05).The total effective rate of treatment was 80.00%,which was significantly higher than 34.62%in the chemotherapy group,and the difference was statistically significant(P＜0.05).The total incidence of adverse reactions(33.33%)in the combination group was significantly lower than that in the chemotherapy group(92.31%),and the difference was statistically significant(P＜0.05).ConclusionCapecitabine combined Thalidomide in the treatment of advanced colorectal cancer has remarkable efficacy,high safety and low adverse reaction rate,so it is worth using in clinical.
2017 Vol. 24 (35): 50-52 [
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Curative effect of laparoscopic radical resection of colon cancer and its effect on gastrointestinal function
LI Shi-hua
ObjectiveTo investigate the curative effect of laparoscopic radical resection of colon cancer and its effect on gastrointestinal function.MethodsFrom January 2013 to January 2016,a total of 32 patients with laparoscopic radical carcinoma of colon cancer were selected as the observation group,another 30 patients with colon cancer surgery were selected as the control group.The intraoperative blood loss,postoperative anal exhaust time,start into the liquid diet time and the time of hospitalization were compared between the two groups.The changes of gastric motilin (MTL)and complications were compared between the two groups.ResultsThe intraoperative blood loss of patients in observation group was(86.95±11.58)ml,which was less than that in the control group [(127.34±23.47)ml],patients in observation group with postoperative anal exhaust time [(41.31±5.23)h],start into the liquid diet time [(53.97±11.76)h]and the time of hospitalization [(6.34±1.12)d]were both shorter than those in the control group [(68.56±11.17)h,(116.03±31.42)h,(10.32±2.37)d],and the differences were statistically significant(P＜0.05).The preoperative MTL was compared between the two groups,and the difference was statistically significant(P＞0.05).The postoperative MTL level of the patients in the observation group was lower than that in the preoperative and control group,and the differences were statistically significant(P＜0.05).The total incidence of postoperative complications in the observation group(9.4%)was significantly lower than that in the control group(33.3%),and the difference was statistically significant(P＜0.05).Conclusion Laparoscopic radical resection of colon cancer can significantly promote the recovery of gastrointestinal function in patients.
2017 Vol. 24 (35): 53-55 [
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Clinical observation of laparoscopic radical resection of rectal cancer in patients with rectal cancer
LIU Yun-geng
ObjectiveTo investigate the clinical value of laparoscopic radical resection of rectal cancer in patients with rectal cancer.MethodsFrom April 13,2011 to May 5,2016,90 cases of rectal cancer patients who treated in our hospital were divided into two groups according to completely random average method,45 cases in each group.The control group was treated with open resection and the laparoscopic group was treated with laparoscopic radical resection of rectal cancer.The clinical effect,blood loss and life quality score were compared.ResultsThe blood loss of patients in the observation group was[(45.13±6.29)ml],it was lower than that in the control group[(182.81±11.54)ml],and the difference was statistically significant(P＜0.05).The total efficiency of treatment in the observation group(77.78%)was higher than that in the control group(57.78%),and the difference was statistically significant(P＜0.05).After treatment,the social relations,material life,mental state and physical function scores of patients in the observation group[(83.97±3.82),(86.35±2.42),(85.04±3.43)and (80.86±2.38)points]were higher than those in the control group [(74.76±4.31),(79.20±2.25),(75.71±3.39)and(71.82±3.13)point],and the differences were statistically significant(P＜0.05).ConclusionIn the treatment of rectal cancer,laparoscopic radical resection of rectal cancer is effective,with the advantages of small trauma and good prognosis.It′s worth spreading.
2017 Vol. 24 (35): 56-58 [
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The value of joint application of amplitude integrated electroencephalogram scoring system and cranial B-ultrasound in early diagnosis of brain injury in premature infants
YU Cong； YAN Chang-hong ；CAI Jun； JIANG Wen-xing
ObjectiveTo explore the value of combined application of amplitude integrated electroencephalogram(EEG)scoring system and cranial B-ultrasound in early diagnosis of brain injury in premature infants.MethodsAnalysis in June 2016 to June 2017,traumatic brain injury in our hospital 100 cases of premature infants in the inspection and diagnosis.According to the different examination methods,they were evenly divided into control group and experimental group.In the control group,premature infants were provided with cranial B-ultrasound examinations,while in the experimental group,they were provided with amplitude integrated EEG score system and cranial B-ultrasound examinations in combination.Theclinical diagnosis of the two groups were compared and analyzed.ResultsIn the experimental group,the scores of LB,Cy,and Co in the clinical diagnosis were significantly lower than those in the control group (P＜0.05).By ROC curve,Cy score presented with highest specificity and sensitivity in the diagnosis of brain injury in preterm infants,greatly higher than those by LB score and Co score.The application value was utmost in combined diagnosis of Cy,LB,and Co score (P＜0.05).ConclusionFor premature infants with brain injury,joint examinations of amplitude integrated EEG score system and cranial B-ultrasound display high accuracy and specificity with a high clinical application value.
2017 Vol. 24 (35): 59-61 [
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The influence of pre-pregnancy body mass index and weight gain during pregnancy on the perinatal out come
ZHAO Ai-rong； JIANG Jin-feng ；GONG Xue-fen
ObjectiveTo explore the influence of pre-pregnancy body mass index (BMI)and weight gain during pregnancy on the outcome of cesarean section.Methods476 cases of pregnant women,who were checked and had hospital delivery in our hospital from January 2015 to July 2017,were selected as the research objects;the BMI before pregnancy was calculated;weight gain during pregnancy,body weight before delivery,neonatal birth weight and birth outcomes were also traced.The subjects were classified in accord with the China BMI classification standard,including underweight group with 56 cases,normal weight group with 253 cases,overweight group with 126 cases and obese group with 41 cases;according to the weight gain during pregnancy,they were classified into deficient-gain group with 60 cases,normal-gain group with 300 cases,excessive-gain group with 116 cases.ResultsBased on BMI classification,the pregnant women′s GDM rate,macrosomia rate and cesarean section rate of the four groups were significantly different,which were statistically significant(P＜0.05).For the underweight group,macrosomia rate and GDM rate were both zero,and cesarean section rate was 26.78%;for the normal weight group,GDM rate was 7.11%,the macrosomia rate was 4.74%,and the cesarean section rate was 37.54%;for the overweight group,GDM rate was 14.28%,the macrosomia rate was 7.94%,and the cesarean section rate was 54.76%;for the obesity group,the GDM rate was 24.39%,the macrosomia rate was 24.39%,and the cesarean section rate was 60.97%.Based on classification in accord with the weight gain during pregnancy,the GDM rate,macrosomia rate and cesarean section rate of the groups with excessive-gain during pregnancy were significantly higher than those with normal-gain and deficient-gain (P＜0.05).For deficient-gaingroup,the GDM rate was 3.33%,the macrosomia rate was 1.67%,and the cesarean section rate was 30.00%;for normal-gain group,the GDM rate was 6.33%,the macrosomia rate was 6.00%,and the cesarean section rate was 40.33%;for excessive-gain group,the GDM rate was 21.55%,the macrosomia rate was 11.21%,and the cesarean section rate was 56.03%.Conclusionfor those with higher pre-pregnancy body mass index and excessive weight gain during pregnancy,there are also higher incidences of GDM,macrosomia and cesarean section.
2017 Vol. 24 (35): 62-64 [
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Relationship between thyroid peroxidase antibody and thyroid function and adverse pregnancy outcomes in pregnancy
CHEN Hong
ObjectiveTo discuss the relationship between thyroid peroxidase antibody(TPOAb)and thyroid function and adverse pregnancy outcomes in pregnancy.Methods242 pregnant women who visit at department of obstetrics and gynecology in our hospital from Feb 2016 to Apr 2017 and level of thyroid hormone was normal were divided into the observation group(n=120,TPOAb positive)and the control group(n=122,TPOAb negative)according to the results of TPOAb results.Then the thyroid function and adverse pregnancy outcomes were contrasted between the two groups.ResultsThe incidence of thyroid dysfunction was 20.8%in the observation group,which was significantly higher than 7.3%in the control group(P＜0.05).The incidence of adverse pregnancy outcome was 30.0%,which was significantly higher than 12.3%in the control group (P＜0.05).ConclusionThe incidence of thyroid hormone abnormal and adverse pregnancy outcome in middle and late pregnancy is high in TPOAb positive pregnant woman,and thyroid function tests should be strengthened in pregnancy,and improve pregnancy safety.
2017 Vol. 24 (35): 65-67 [
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202
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Effect of precise insulin infusion during perioperative period of patients with gestational diabetes mellitus on blood glucose level in neonates
ZOU Yin-xia
ObjectiveTo investigate the effect of precise insulin infusion during perioperative period of patients with gestational diabetes mellitus on blood glucose level in neonates.MethodsAltogether 100 patients with gestational diabetes mellitus who underwent termination of pregnancy by cesarean section in our hospital from January 2015 to January 2017 were selected and divided into the experiment group and the control group,with 50 cases in each group.The experiment group was given intravenous drip of glucose at 70-100 mg/h 1 h before surgery;when patients′blood sugar was more than or equal to 5.6 mmol/L,the experiment group was given regular insulin(glucose value×0.12 U/h);the control group was given Ringer′s solution preoperatively.The changes in maternal blood glucose level,preoperative blood glucose level,neonatal blood glucose level and blood glucose level 1 h after birth were compared between the two groups.ResultsThe maternal blood glucose index,neonatal blood glucose index and neonatal blood glucose index 1 h after birth of experiment group were better than those of control group,with statistically significant difference (P＜0.05);the incidence rate of neonatal hypoglycemia of control group was 20%,which was significantly higher than that of experiment group (6%),with statistically significant difference (P＜0.05).ConclusionTreatment with glucose and intravenous insulin pump infusion in pregnant women with gestational diabetes mellitus during perioperative period can effectively promote the maintenance of maternal and neonatal blood glucose levels at a relatively stable state and reduce the incidence of neonatal hypoglycemia,ensuring neonatal health.
2017 Vol. 24 (35): 68-70 [
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186
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The effect of laparoscopic total hysterectomy on the treatment of patients with gastrointestinal function and pelvic floor function
FU Xiao-hong
ObjectiveTo explore the effect of total hysterectomy on patients and the recovery of gastrointestinal function.MethodsFrom January 2015 to July 2017,260 cases of hysterectomy patients in our hospital were selected as the research objects,and the related datas were retrospectively analyzed,according to the operation method,patients were divided into two groups,the observation group were treated with laparoscopic hysterectomy in the treatment,a total of 160 cases.Ccontrol group patients adopted open surgery for treatment,a total of 100 cases,the therapeutic effect of two groups were observed,and compared two groups of patients with gastrointestinal function recovery and so on.ResultsThe operation time of the observation group was similar to the control group,and the difference was not statistically significant(P＞0.05).Observation group total blood loss less than control group in the operation,for the first time of bed activity time,length of hospital stay,anal exhaust time,defecation time,for the first time after eating time score are shorter than the control group,the complication rate is lower than the control group,the difference was statistically significant(P＜0.05)..ConclusionThe clinical application effect of laparoscopic hysterectomy is good,and the postoperative gastrointestinal function of patients was quick and it used to be worth spreading.
2017 Vol. 24 (35): 71-73 [
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194
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Effect of delivery ball combined with music therapy on the stages of labor and pain sensation of parturients in childbirth
LI Gui-rong ；YANG Yu-ting
ObjectiveTo study the effect of delivery ball combined with music therapy on the stages of labor and pain sensation of parturients in childbirth.MethodsA total of 90 parturients who gave childbirth in our hospital from March 2016 to March 2017 were selected and randomly divided into observation group and control group,with 45 cases in each group.The control group was given routine midwifery;while the observation group was given delivery ball combined with music therapy for midwifery.The stages of labor and pain severity of the two groups were observed.ResultsThe time spent in each stage of labor of observation group were shorter than that of control group,with statistically significant difference(P＜0.05);the maternal pain sensation of observation group was significantly lighter than that of control group,with statistically significant difference (P＜0.05).ConclusionApplication of delivery ball combined with music therapy in childbirth can effectively shorten the duration in each stage of labor and reduce the pain in the process of childbirth.
2017 Vol. 24 (35): 74-76 [
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181
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77
Comparison of the efficacy of Reduning and Ribavirin in children with respiratory infection and effects on inflammatory factors
CAI Jie-ping； LU Zhi-ping ；FU Zhi-wei
objective To investigate the therapeutic effect of Reduning and Ribavirin in children with respiratory infection and the influence on inflammatory factors.MethodsFrom September 2015 to September 2016,80 children suffering from respiratory tract infection in our hospital were selected.According to the principle of random allocation,they were divided into observation group and control group,40 cases in each group.The observation group were treated by conventional treatment,on the basis of using Reduning treatment,the control group was treated with conventional treatment,on the basis of using the Ribavirin treatment.SF-36 scale simple quality of life scale was used to assess the quality of life of the two groups after treatment,different treatment effect between the two groups and the Reduning and Ribavirin influence of the TNF-α and IL-6 were compared.ResultsThe total effective rate of the observation group after treatment was significantly higher than that of the control group,the difference was statistically significant(P＜0.05);the social function,physical function,role function,cognitive function score of observation group after treatment were compared with the control group,the differences were statistically significant(P＜0.05);the observation group after treatment,serum TNF-α and IL-6 index were lower than those of the control group,the differences were statistically significant(P＜0.05).Conclusion In the clinical treatment of children with respiratory tract infection,the treatwent effect of Reduning is significant,it can quickly relieve the clinical symptoms of the patients,significantly reduced the serum TNF-α,IL-6.
2017 Vol. 24 (35): 77-79转82 [
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211
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Analysis of the effect of cystoscope conbination with ureter intubation in cesarean section
HUANG Hui-Juan； XU Qiao-ying；HUANG Gui-lian
ObjectiveTo investigate the safety and feasibility of cystoscopy in cesarean section that delayed dehiscence or postpartum hemorrhage.MethodsRetrospective analysis of 60 patients which sutued cervix becaused of delayed dehiscence or rich bleeding in cesarean section from January 2014 to December 2016 in Ruijin Maternal and Child Health Care Hospital.Patients who underwent intraoperative cystoscopy combined with ureter catheterization were considered as research group.Patients who just underwent routine detection of ureter anatomical location were considered as control group.And the operation time,bleeding volume,suture of ureter,cond operation,postoperative infection and complications were analyzed and compared between the two groups.ResultsCompared with the control group,operation time was significantly shortened in the research group[(50±10)min vs.(60±10)min](P=0.0003)and intraoperative bleeding was significantly less[(300±20)ml vs.(350±30)ml](P=0.0000).Postoperative suture and second operation were significantly happened less in research group(P=0.0166,P=0.0303),The postoperative complications were compared with the control group,and the difference was not statistically significant(P＞0.05).ConclusionCombination intraoperative cystoscopy withureter catheterization may reduce shorten the operation time and reduce the risk of ureteral ligation and second operation in the cesarean section that requiring suture near the cervix.
2017 Vol. 24 (35): 80-82 [
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166
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83
Effect of small incision extracapsular surgery on senile cataract
WANG Zi-chuan； DONG Xiao-ming； LI Cai-bao
ObjectiveTo investigate the clinical curative effect of different surgical procedures on senile cataract.Methods80 cases of senile cataract patients(grade 3 and above)who treated from April 2015 to April 2017 were selected as subjects and were divided into two groups according to random number table method,40 cases in each group.The patients in the control group were treated with phacoemulsification.The patients in the observation group were treatedwithsmallincisionextracapsularsurgery.Aftertreatmentintervention,thevisualacuityof1week,1monthand3months after surgery and the incidence of postoperative complications of the two groups were compared.ResultsThere was no statistically significant difference between the two groups of 1 week,1 month and 3 months after surgery (P＞0.05).The incidence of postoperative complications was 5.00%in the observation group and 20.00%in the control group,the incidence of postoperative complications in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P＜0.05).ConclusionIn the treatment of senile cataract with small incision extracapsular surgery,the clinical effect is satisfactory,which can effectively reduce the incidence of postoperative complications and is worthy of clinical promotion.
2017 Vol. 24 (35): 83-85 [
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174
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86
Clinical application effect of mini self tapping titanium implant anchorage
WANG Hai-ren；WANG Hong-ning；QIN Hang-lin
ObjectiveTo investigate the clinical application effect of mini self tapping titanium implant anchorage.MethodsFrom February 2014 to January 2016,60 cases of adult biomaxillary protrusion who treated in orthodontics department of our hospital were selected as subjects and divided into the observation group and the control group according to the random number table method,30 cases in each group.The control group was treated with extraoral arch anchorage,and the observation group was treated with mini self tapping titanium implant anchorage.The correction effect,the treatment adherence and the change of SNA,SNB index before and after dental treatment were compared between the two groups.ResultsAll patients were successfully completed dental treatment and were reached the classⅠrelationship of molar.The successful rate of planting in the observation group was 96.7%.The compliance of the observation group during dental treatment was 96.7%,while the compliance was 76.7%in the control group,the index in the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).The decrease of the SNA angle in the observation group was[(0.42±0.33)°],while the decrease of the SNA angle in the control group was[(0.24±0.14)°],and the difference was statistically significant(P＜0.05).ConclusionThe clinical application of mini self tapping titanium implant anchorage has better anchorage effect,and the orthodontic treatment has higher success rate and increase the compliance,so it deserves clinical promotion.
2017 Vol. 24 (35): 86-88 [
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165
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Application effect analysis of short duration occlusion combined with Atropine in the treatment of children with diatric amblyopia
ZHANG Zi-yin
ObjectiveTo investigate the clinical effect of short duration occlusion combined with Atropine in the treatment of children with diatric amblyopia.Methods91 cases of children with amblyopia who treated in our hospital from February 2015 to July 2016 were selected as the research subjects,and were devided into two groups according to different treatment methods.The control group (40 cases)were treated with short-term occlusion,while the observation group (51 cases)were treated with short-term occlusion combined with Atropine.The treatment effect,visual acuity and treatment compliance of two groups were compared.ResultsThe total effective rate in the observation group was 92.16%,which was higher than that in the control group of 75.00%,and the difference was statistically significant(P＜0.05).Before the treatment,there was no significant difference in visual acuity between the two groups (P＞0.05).After treatment for 6,9 and 12 months,the visual acuity in the observation group were better than those in the control group,the differences were statistically significant(P＜0.05).The treatment compliance in the observation group was 94.12%,compared with the control group of 77.50%,the difference was statistically significant(P＜0.05).ConclusionThe short-term occlusion combined with Atropine are better than that the short-term duration occlusion in the treatment of children with amblyopia,which can promote the improvement of vision of children,and it have high compliance of children,thus it is worthy to be promoted in the clinical.
2017 Vol. 24 (35): 89-91 [
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173
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92
The efficacy of the supragingival scaling combined with Ominqing in the treatment of chronic simple gingivitis
LIU Qi
ObjectiveTo investigate the curative effect of supragingival scaling combined with Ominqing in the treatment of chronic simple gingivitis.MethodsFrom March 2016 to February 2017,88 cases of simple gingivitis patients who treated in our hospital were selected as subjects and divided into the control group and the combined treatment group according to the method used，44 cases in each group.The control group was treated with supragingival scaling surgery.The combination therapy group was treated with supragingival scaling combined with Ominqing.The control total efficiency of gingivitis,the periodontal correlation indexs before and after treatment,the scores of chewing efficacy and the quality of life before and after treatment,the incidence of adverse reaction and the recurrence rate were compared between the two groups.ResultsThe control total efficiency of gingivitis in the combined treatment group was higher than that in the control group,and the difference was statistically significant(P＜0.05).Before treatment,the periodontal correlation index was compared between the two groups,and the difference was not statistically significant(P＞0.05).After treatment,the periodontal correlation indexs in the combined treatment group were lower than that in the control group,and the differences were statistically significant(P＜0.05).Before treatment,the scores of chewing efficacy and quality of life were compared between the two groups,and the differences were not statistically significant(P＞0.05).After treatment,the scores of chewing efficacy and quality of life in the combined treatment group were higher than those in the control group,and the differences were statistically significant(P＜0.05).The incidence of adverse reaction was compared between the two groups,and the difference was not statistically significant(P＞0.05).The recurrence rate of the combined treatment group was lower than that of the control group,and the difference was statistically significant(P＜0.05).ConclusionSupragingival scaling combined with Ominqing on the efficacy of chronic simple gingivitis is effective,can effectively improve the patient′s condition,eliminate periodontal symptoms,promote chewing function and improve the quality of life of patients,the effect is sure,worthy of promotion.
2017 Vol. 24 (35): 92-94 [
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165
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Clinical study of stellate ganglion block combined with retroauricular Methylprednisolone injection in the treatment of sudden deafness
FAN Zhou-hong；YI Tao；LI Juan
ObjectiveTo investigate the clinical effect of stellate ganglion block combined with retroauricular Methylprednisolone injection in the treatment of sudden deafness.MethodsFrom November 2015 to November 2016,80 patients with sudden deafness treated in our hospital were enrolled.According to the degree of hearing impairment,they were evenly divided into the control group and the observation group in random,40 cases in each group.In the control group,conventional treatment including retroauricular methylprednisolone injection,vasodilator to improve microcirculation drug,and neurotrophic drug was used.In the observation group,stellate ganglion block combined with retroauricular Methylprednisolone injection was applied.After therapy,the clinical effect in the two groups was compared.ResultsThere was no significant difference in the average hearing threshold before treatment between the two groups(P＞0.05).After therapy,the threshold was improved in both groups,which was more significant in the observation group(P＜0.05).Compared with the control group,the total effectiveness rate in the observation group was significantly higher(P＜0.05).The incidence rate of adverse reactions in the observation group was 5.0%,which was lower than that of the control group(22.5%),with significant difference(P＜0.05).ConclusionFor the patients with sudden deafness,combination of stellate ganglion block and retroauricular Methylprednisolone injection can remarkably improve the overall therapeutic effect of sudden deafness.
2017 Vol. 24 (35): 95-97 [
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154
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Application effect of small dose Fentanyl combined with Sevoflurane in laryngeal mask airway for elderly patients undergoing hernia repair
XU Yong-min
ObjectiveTo investigate the application effect of small dose Fentanyl combined with Sevoflurane in laryngeal mask airway in elderly patients undergoing hernia repair.MethodsFrom February 2015 to August 2016,76 elderly patients with laryngeal mask airway hernia repair were selected as the research object,and divided into the composite group and the control group according to different anesthesia methods,each group had 38 cases.The composite group
received
anesthesia with a small dose of Fentanyl combined with Sevoflurane.The control group received only Sevoflurane anesthesia.The level of heart rate(HR),mean arterial pressure(MAP),pulse oxygen saturation(SpO2),Partial pressure of carbon dioxide at the end of respiration (PETCO2)changes were compared between the two groups,and anesthesia induction time,recovery time and the incidence of adverse reaction were observed between the two groups.ResultsThe anesthesia induction time and postoperative recovery time of the composite group were shorter than those of the control group,and the difference was statistically significant(P＜0.05).After anesthesia,the level of HR,PETCO2in the composite group were lower than those in the control group,and the level of MAP and SpO2were higher than those in the control group,the difference was statistically significant(P＜0.05).The incidence of adverse reactions in the composite group was lower than that in the control group(5.26%vs.23.68%),and the difference was statistically significant(P＜0.05).ConclusionA small dose of Fentanyl and Sevoflurane in laryngeal mask airway in elderly patients undergoing hernia repair can make the patient′s intraoperative anesthesia and postoperative recovery time more convenient control,higher safety,better anesthetic effect,and reduce the incidence of adverse events,it is worth promoting and application.
2017 Vol. 24 (35): 98-100 [
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174
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Analysis of clinical efficacy and safety of Sufentanil combined with Dezocine for postoperative analgesia of secondary cesarean section
LI Qing-yu
ObjectiveTo investigate the clinical efficacy and safety of Sufentanil combined with Dezocine in the postoperative analgesia of secondary cesarean section.MethodsFrom February 2015 to February 2016,56 puerperae after second cesarean section admitted into our hospital were selected.By a random number table method,they were divided into group A(n=30)and group B(n=26).In group A,Sufentanil combined with Dezocinewas used for postoperative analgesia,while in group B,Onlydezocine was applied.The visual analogue scale (VAS)score after analgesia and incidence rate of adverse reactions in puerperae were compared between the two groups.ResultsThe oral pain and VAS score in group A were both lower than that in group B,with statistical differences (P＜0.05).The incidence rate of adverse reactions in group A was 3.33%,which was significantly lower than that in group B accounting for 23.07%,with a statistical difference (P＜0.05).ConclusionThe application of Sufentanil combined with Dezocinefor postoperative analgesia can effectively decrease the VAS scorein puerperae after second cesarean section,alleviate the postoperative painful sensation,and reduce the incidence rate of adverse reactions,which has a certain clinical value.
2017 Vol. 24 (35): 101-103 [
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182
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Application of different doses of Butorphanol combined with surface anesthesia in clear endotracheal intubation
CHEN Deng
ObjectiveTo explore the specific application of the combined surface anesthesia of Butorphanol in clear endotracheal intubation.MethodsFrom September 2016 to May 2017,100 patients underwent clear endotracheal intubation in our hospital were selected as the research object,according to the random numbers table method,all patients were divided into group A,group B,group C,group D,group E,20 cases in each group.Group A was given simple anesthesia,group B was given the surface anesthesia combined with 20 μg/kg Butorphanol,group C was given 40μg/kg Butorphanol surface anesthesia,group D was given 60 μg/kg Butorphanol surface anesthesia,group E was given surface anaesthesia plus Propofol and Fentanyl.The anesthetic effect of the five groups was compared.ResultsThe SpO2level of group B,group C,and group D at T2-T3were lower than that of group A,with significant difference(P＜0.05).There was no significant difference in the SpO2level at T2-T3between group A and group E(P＞0 0.05).The levels of HR and MAP in group E and group A at T3were lower than that in group B,group C and group D,with significant differences(P＜0.05).The level of HR and MAP at T2in group A,group B,group E group was higher than that in group C,group D,with significant difference (P＜0.05).There was no significant difference in the level of HR and MAP at T2between group C and group D(P＞0.05).The incidence rates of nausea,cough and agitation in group A,group B,group E were significantly higher than that in group C,and the proportion of successful intubation in group A,group B,group E was lower than that in group C,group D,with significant differences(P＜0.05).There was significant difference in the incidence rate of nausea,cough,agitation and the proportion of successful intubation between Group C and group D(P＞0.05).ConclusionIn the process of clear endotracheal intubation,the dose of Butorphanol is maintained at 40-60 μg/kg,which is beneficial to reduce the stress reaction and the incidence of adverse reactions during intubation,improve the success rate of intubation,and it is worth popularizing in clinic.
2017 Vol. 24 (35): 104-106 [
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Comparison of the application effect of general anesthesia and general anesthesia combined with epidural anesthesia on joint replacement
XU Huan-lin； ZHU Hua-fen
ObjectiveTo investigate the application effect of general anesthesia and general anesthesia combined with epidural anesthesia on joint replacement.Methods74 patients with total hip replacement in our hospital from March 2015 to September 2016 were selected as the subjects.The patients were divided into the observation group (n=37)and the control group (n=37)according to different anesthesia mode.The observation group was given general anesthesia combined with epidural anesthesia,and the control group was given general anesthesia.The amount of bleeding and the time needed for complete block were compared between the two groups.The blood pressure and heart rate at different time points were counted,the time of ambulation and the difference of postoperative cognitive function between the two groups were statistically analyzed.ResultsThere was no significant difference between the two groups in the amount of bleeding and the time of ambulation after operation (P＞0.05).The complete block time of the observation group was shorter than that of the control group,and the heart rate and MAP indexes in the operation were better than those in the control group (P＜0.05).The MMSE score of the observation group at 6,12,24 h after operation was higher than that of the control group (P＜0.05).ConclusionThe effect of general anesthesia combined with epidural anesthesia on hemodynamics and cognitive function of patients is smaller,and has better clinical application value.
2017 Vol. 24 (35): 107-109 [
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180
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Influence of Penehyclidine Hydrochloride on cognitive dysfunction in elderly patients after general anesthesia in department of orthopedics
LIAO Sheng-gen； LI Kun；ZHANG Gui-hua
ObjectiveTo investigate the influence of Penehyclidine Hydrochloride on cognitive dysfunction in elderly patients after general anesthesia in department of orthopedics.MethodsFrom April 2015 to August 2016,144 cases of elderly general anesthesia patients in department of orthopedics in our hospital were selected and divided into group A,group B,group C according to different treatment methods,each group had 48 cases.Group A
received
intramuscular injection of Penehyclidine Hydrochloride 1.0 mg at 30 min before operation,group B received intramuscular injection of Atropine 0.5 mg,group C were not treated with any prior medication.The MMSE score and the incidence rate of POCD at preoperative 1 day and postoperative 1 day,3 days were compared between the three groups.ResultsThe MMSE scores of the three groups at preoperative 1 day were lower than that of at the postoperatively 1 day,3 days,and the difference was statistically significant(P＜0.05).The MMSE score of group A at postoperative 1 day,3 days were significantly lower than those in group B and group C,and the difference was statistically significant(P＜0.05).The incidence rate of POCD in group A was lower than that group B and group C,the difference was statistically significant(P＜0.05).ConclusionPenehyclidine Hydrochloride should be used for elderly patients with general anesthesia in department of orthopedics can reduce the incidence of patients with POCD,and which has a related influence on the postoperative cognitive function of the patients,it should be paid attention to.
2017 Vol. 24 (35): 110-112 [
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Observation of clinical application effect of combined spinal epidural anesthesia on labor analgesia during latent phase in parturients
PENG Wei；KUANG Min-liang
ObjectiveTo study the clinical effect of combined spinal epidural anesthesia on labor analgesia during latent phase in parturients.MethodsAltogether 96 primiparas who were treated in our hospital from February 2015 to August 2016 were selected and divided into the control group and the observation group according to use or non-use of labor analgesia,with 48 cases in each group.The control group was not given labor analgesia,while the observation group was treated with combination of subarachnoid block anesthesia (lumbar anesthesia)and epidural anesthesia for labor analgesia.The blood pressure(BP),heart rate(HR),respiratory rate(RR),blood oxygen saturation(SpO2),fetal heart rate(FHR)as well as the stage of labor,mode of delivery and adverse reactions were compared between the two groups.ResultsThe level of BP and HR of the observation group were lower than those of the control group,with statistically significant difference (P＜0.05).There was no statistically significant difference between the level of RR,SpO2and FHR between the two groups(P＞0.05).The latency time of the first stage of labor of the observation group was significantly shorter than that of the control group,with statistically significant difference(P＜0.05).There was no statistical significance in the active phase of the first stage of labor,the second and third stage of labor as well as the mode of delivery between the two groups(P＞0.05).The incidence of adverse reactions was 6.25%(3/48)in the observation group and 0%(0/48)in the control group,without significant difference between the two groups (P＞0.05).ConclusionApplication of combined spinal epidural anesthesia for labor analgesia on maternal latency shows rapid and clear analgesic effect and less adverse reactions,and can effectively shorten the stage of labor to reduce the cesarean section rate,which is worthy of clinical application.
2017 Vol. 24 (35): 113-115 [
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204
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Application effect of N2O inhalation in photodynamic therapy for condyloma acuminata
LIN Zhi-ming
ObjectiveTo investigate the application effect of nitrous oxide(N2O)inhalation in photodynamic therapy for condyloma acuminata.MethodsFrom June 2016 to June 2017,128 patients with condyloma acuminata who were treated by photodynamic therapy in our hospital were enrolled as research objects.According to different therapeutic methods,they were divided into the N2O group (n=60)and the Tramadol group (n=68).The NRS pain scores during and after surgery,and adverse drug reactions were compared between the two groups.ResultsIn the N2O group,the analgesic effect by inhalation of N2O was greatly better than that of oral administration of the Tramadol group (P＜0.01).The vital signs were stable in the process of surgery and after surgery in both groups.The overall incidence of adverse events in the N2O group was 13.33%,and 11.76%in the Tramadol group,without a significant difference after comparison between the two groups(P＞0.05).ConclusionN2O inhalation can effectively alleviate the pain in the treatment of condyloma acuminatum by photodynamic therapy in high drug safety.
2017 Vol. 24 (35): 116-118 [
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199
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Effect on the application of Dexmedetomidine in general anesthesia of orthopedic joint replacement
CHEN Yi-xi
ObjectiveTo investigate the application effect of Dexmedetomidine in general anesthesia of orthopedic joint replacement.Methods74 patients undergoing orthopedic joint replacement who were admitted to our hospital from April 1,2016 to March 31,2017 were selected and randomly divided into the observation group and the control group,with 37 cases in each group.The observation group was given Dexmedetomidine intravenous infusion,and the control group was given intravenous infusion of equal volume of normal saline.The MMSE score,S100β level,hemodynamics and adverse events were compared between the two groups of patients undergoing orthopedic joint replacement.ResultsThere was significant difference in the MMSE score and S100β level between the observation group at 3 days and 1 week after treatment and those in the control group (P＜0.05).The levels of HR at T3,T4,T5and CVP and MAP at T5in the observation group in the patients undergoing orthopedic joint replacement were significantly lower than those in the control group (P＜0.05).The incidence rate of adverse reactions in the patients undergoing orthopedic joint replacement in the observation group was lower than that in the control group(P＜0.05).ConclusionThe application of Dexmedetomidine in general anesthesia of orthopedic joint replacement can improve the cognitive function and hemodynamic indices of patients,reduce the incidence of adverse reactions,and the antihypertensive effect is significant.
2017 Vol. 24 (35): 119-121 [
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Efficacy of hypertonic saline combined with Budesonide Inhalation in the treatment of capillary bronchitis in children
DAI Ben-qi；CHEN Jie； LUO Yu-ting ；ZHANG Zhi-mei
ObjectiveTo investigate the effect of 3%hypertonic saline combined with Budesonide Inhalation on capillary bronchitis.MethodsTotally 250 cases of children with capillary bronchitis treated in our hospital from January 2015 to January 2017 were randomly divided into two groups according to odd or even of the hospital bed last one number,each group has 125 cases.During hospitalization,children were both given anti-infection,cough and symptomatic treatment.The therapy group was treated with 3%hypertonic saline 2 ml cmobined with 0.5 mg Budesonide Inhalation the control group was treated with 0.9%saline solution 2 ml combined with 0.5 mg of Budesonide Inhalation.The wheezing remission time,moist crackles disappearance time and the length of hospital stay between the two groups were compared.The treatment effect of 7 d was compared between the two groups.ResultsThe wheezing remission time,moist crackles disappearance time and the length of hospital stay of children in the therapy group were shorter than those in the control group,and the differences were statistically significant(P＜0.05).The total treatment effective rate in the therapy group(97.00%)was higher than that in the control group(88..00%),and the difference was statistically significant(P＜0.05).ConclusionThe effect of 3%hypertonic saline combined with Budesonide Inhalation therapy in the treatment of capillary bronchitis in children is significant,and it is worthy of clinical promotion.
2017 Vol. 24 (35): 122-124 [
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Clinical study of Madopar combined with Pramipexole Hydrochloride for the treatment of Parkinson′s disease
YANG Xing-hong； SU Yu-rong ；LI Xin
ObjectiveTo investigate the therapeutic effect Madopar combined with Pramipexole Hydrochloride for the treatment of Parkinson′s disease.MethodsAltogether 124 patients with Parkinson′s disease who were treated in our hospital from April 2013 to April 2016 were selected as the research objects and divided into control group(62 cases,treated with Madopar)and observation group (62 cases,treated with Madopar combined with Pramipexole Hydrochloride)according to the random number method.The treatment efficiency,Parkinson′s score scale (UP-DRS),quality of life scale(ADL)score and clinical adverse reactions were compared between the two groups.ResultsBefore the treatment,the UP-DRS score of patients in two groups were compared,and the difference was not statistically significant(P＞0.05).While in 6 weeks and 12 weeks after treatment,the observation group of patients with the UP-DRS scores were significantly lower than the control group,the differences were statistically significant(P＜0.05).The total incidence of adverse reactions in the two groups was compared,and the difference was not statistically significant(P＞0.05).The ADL score of the patients in the observation group was significantly higher than that in the control group,and the difference was statistically significant(P＜0.05).The total effective rate of treatment in the observation group was significantly higher than that in the control group,and the difference was statistically significant(P＜0.05).ConclusionThe therapeutic effect of Madopar combined with Pramipexole Hydrochloride for the treatment of Parkinson′s disease is significantly improved,and it is worth promoting to improve treatment efficiency without increasing the adverse reaction of patients.
2017 Vol. 24 (35): 125-127 [
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175
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128
Clinical efficacy and safety analysis of Clindamycin combined with Gynecological Qianjin Tablets in the treatment of chronic pelvic inflammatory disease
Deng Ling-ling
ObjectiveTo investigate the clinical efficacy and safety of Clindamycin combined with Gynecological Qianjin Tablets in the treatment of chronic pelvic inflammatory disease.MethodsFrom May 2015 to November 2016,162 cases of patients with chronic pelvic inflammatory disease who treated in our hospital were selected as subjects,and they were divided into single drug group and combined drug group according to different treatment methods,81 cases in each group.The single drug group was treated with Clindamycin,the combined drug group was treated with Clindamycin combined with Gynecological Qianjin Tablets.The scores of clinical symptoms,clinical efficacy and adverse reactions were compareed between the two groups.ResultsAfter treatment,the scores of lower abdominal pain,swelling,leucorrhea,leucorrhea and lassitude in the combined drug group were lower than those in the single drug group,the differences were statistically significant(P＜0.05).The total effective rate of the combined drug group(97.53%)was higher than that of the single drug group(87.65%),the difference was statistically significant(P＜0.05).The incidence of adverse reactions in the combined drug group(6.17%)was significantly lower than that in the single drug group(17.28%),the difference was statistically significant (P＜0.05).ConclusionClindamycin combined with Gynecological Qianjin Tablets in the treatment of chronic pelvic inflammatory disease can effectively relieve the clinical symptoms,improve the clinical efficacy,less adverse reactions,and have high clinical value,so it is worthy of popularization and application.
2017 Vol. 24 (35): 128-130 [
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201
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131
The efficacy and safety analysis of Lobaplatin combined with Recombinant Interleukin-2 peritoneal injection for the treatment of malignant ascites
ZOU Cai-liang ；WANG Hong-yun； WU Yan-ling ；XIA Xiao-long
ObjectiveTo investigate the efficacy and safety analysis of Lobaplatin combined with Recombinant Interleukin-2 peritoneal injection for the treatment of malignant ascites.Methods34 patients with malignant ascites from March 2015 to March 2017 treated in our hospital were selected as subjects,and they were divided into two groups according to the number of singular or double digits of the admission date,17 cases in each group.The control group was treated with 50 ml of Physiological Saline,60～100 mg of Lobaplatin and 10 mg of Dexamethasone with peritoneal perfusion,the observation group was treated with 50 ml of Physiological Saline,60～100 mg of Lobaplatin,10 mg of Dexamethasone and 1 million U Interleukin-2 with peritoneal perfusion.The clinical efficacy,quality of life (KPS)scores and adverse effects of the two groups were compared.ResultsThe total efficiency of treatment was compared between the two groups,and the difference was not statistically significant(P＞0.05).The proportion of improvement of KPS score in the observation group was higher than that in the control group,and the proportion of decrease was lower than that in the control group,and the differences were statistically significant(P＜0.05).The occurrence of adverse effects were compared between the two groups,the differences were not statistically significant(P＞0.05),and the incidence of leukocyte reduction and bone marrow suppression were higher in both groups,and the incidence of other adverse effects were lower.ConclusionThe treatment of malignant ascite with Lobaplatin combined with Recombinant Interleukin-2 peritoneal injection can improve the clinical efficacy and improve the quality of life of patients.
2017 Vol. 24 (35): 131-133转137 [
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152
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134
The economic value analysis of pharmaceutical intervention in community hypertension patients
LUO Zhen-hui
ObjectiveTo investigate the economic value of pharmaceutical intervention as a treatment in community hypertension patients.Methods300 community hypertension patients treated in Xixiang Street of Bao′an Central Hospital from January 2013 to December 2015 were selected as research objects.According to blood pressure measurement and body weight index,patients were evenly divided into two groups,150 cases in each group.Patients in control group were treated with traditional pharmaceutical intervention,and patients in observation group were treated with individualized drug intervention.The blood pressure control,medication compliance,living habits and treatment cost were compared between the two groups.ResultsAfter intervention,the diastolic and systolic blood pressure levels of patients in two groups were significantly lower than before intervention,the differences were statistically significant(P＜0.01),the diastolic and systolic blood pressure levels of patients in observation group was obviously lower than those in the control group,the differences were statistically significant(P＜0.05).The patients with medication adherence and life habits of observation group were better than control group,and the differences were statistically significant(P＜0.05).The total cost of treatment for patients in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P＜0.05).ConclusionPharmaceutical intervention can reduce the cost of treatment in community hypertension patients,and is helpful to control blood pressure and improve medication compliance in a high economic value.
2017 Vol. 24 (35): 134-137 [
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155
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138
Influence of addition and subtraction of Xiaoke Prescription combined with Metformin Tablets on HOMA-IR and hemorheology in patients with type 2 diabetes mellitus
LI Shu-bing；ZHANG Tai-yang；LIANG Jia-lang
ObjectiveTo investigate the influence of addition and subtraction of Xiaoke Prescription combined with Metformin Tablets on HOMA-IR and hemorheology in patients with type 2 diabetes mellitus(T2DM).MethodsNinety patients with T2DM (Qi-Yin deficiency)treated in our hospital from January 2015 to May 2017 were enrolled in the study and were grouped according to the random data table method,Forty-five patients in the control group were treated with Metformin tablets and Glimepiride to decrease the blood glocose,On this basis,forty-five patients in the observation group were combined with Xiaoke Prescription,and 12 weeks were a course of treatment.The clinical efficacy between the two groups was compared.ResultsAfter treatment,the fasting blood glucose (FBG),postprandial 2 h blood glucose and HOMA-IR level of the two groups were lower than those of the control group,and the difference was statistically significant(P＜0.05).The fibrinogen (Fib)and D-dimer in the observation group were lower than those in the control group,and the difference was statistically significant(P＜0.05).ConclusionThe effect of Xiaoke Prescription combined with Metformin Tablets in the treatment of T2DM is significant and can improve insulin resistance,regulate blood glucose level,and it is better than the use of western medicine alone,it is worth promoting.
2017 Vol. 24 (35): 138-140 [
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176
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141
Clinical effect of western medicine combined with traditional Chinese medicine decoction combined therapy in the treatment of acute exacerbation of chronic bronchitis
HONG Peng
ObjectiveTo explore the clinical effect of western medicine combined with traditional Chinese medicine decoction combined therapy in the treatment of acute exacerbation of chronic bronchitis.MethodsFrom May 2016 to May 2017,52 patients with acute exacerbation of chronic bronchitis patients treated in our hospital were selected as the research object,and they were divided into the study group and reference group,and each group had 26 cases.Patients in the control group was given relieving cough and reducing sputum,relieving inflammation and asthma,symptomatic support routine and other western medicine treatment while patients in the study group were treated with Chinese medicine decoction on the basis of routine western medicine treatment in the control groupt.The clinical efficacy and improvement time of clinical symptoms were observed and compared in patients between the two groups.ResultsThe total effective rate of treatment was 96.15%in patients of the study group,which was significantly higher than that of the reference group (80.77%),and the difference was statistically significant(P＜0.05).The antifebrile time,antitussive time and the disappeared time of pulmonary rales in patients of the study were significantly shorter than those of the control group,and the differences were statistically significant(P＜0.05).ConclusionTreating chronic bronchitis with Chinese herbal decoction on the basis of Western medicine symptomatic treatment has significant curative effect,can effectively promote the improvement of clinical symptoms of chronic bronchitis,improve the total effective rate of treatmen,thus it is worthy of clinical further promotion and application.
2017 Vol. 24 (35): 141-143 [
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192
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Effect observation of Maxing Sizi Decoction combined with mechanical assisted expectoration treating hypostatic pneumonia
TANG Si-wei；OUYANG Wen-juan；LIU Lu；WANG Zhi-ming
ObjectiveTo explore the clinical effect of Maxing Sizi Decoction combined with mechanical assisted expectoration treating hypostatic pneumonia.Methods60 Patients with hypostatic pneumonia treated in Department of Geriatrics of our hospital from August 2016 to April 2017 were selected and randomly divided into the combined group(Maxing Sizi Decoction+mechanical assisted expectoration+conventional Western medicine treatment,30 cases)and the conventional group (conventional western medicine treatment,30 cases).PaCO2,PaO2,FEV1/FVC before and after treatment and hospital stay,the curative effect in patients between the two groups were compared.ResultsBefore treatment,there was no statistical difference of PaCO2,PaO2,FEV1/FVC in patients between the two groups (P＞0.05).After treatment,PaCO2,PaO2,FEV1/FVC were obviously improved compared with before treatment in patients of the two groups,and PaCO2in the combined group was lower than that of the conventional group,PaO2,FEV1/FVC in the combined group were higher than those of the conventional group (P＜0.05).The hospital stay in the combined group was shorter than that of the conventional group(P＜0.05).The total effective rate of the patients in the combined group was 96.67%,which was significantly higher than that of the routine group(73.33%)(P＜0.05).ConclusionMaxing Sizi Decoction combined with mechanical assisted expectoration treating hypostatic pneumonia can help improve the symptoms and improve the clinical efficacy of patients with significant therapeutic effect.
2017 Vol. 24 (35): 144-146 [
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160
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Clinical effect of Fuzheng Huayu Capsules combined with Entecavir in the treatment of liver cirrhosis of hepatitis B
ZHANG Sheng-yu；ZHOU Fu-cheng；NIU Yu-lan；WU Qian
ObjectiveTo investigate the clinical effect of Fuzheng Huayu Capsules combined with Entecavir in the treatment of liver cirrhosis of hepatitis B.MethodsFrom January 2013 to December 2016,120 patients with liver cirrhosis of hepatitis B treated in Zhongwu Hospital of Suqian City were selected and they were divided into the observation group(n=60)and control group(n=60)in random.The Compound Glycyrrhizin,Reduced Glutathione,liver protection,and enzyme decrease were provided in both groups.In the control group,oral administration of Entecavir Dispersible Tablets was applied,0.5 mg each time,once a day.In the observation group,Fuzheng Huayu Capsules for oral administration was adopted,0.2 g each time,3 times per day.Alanine transaminase(ALT),aspartate aminotransferase(AST),albumin(Alb),total bilirubin(TBil),Child-Pugh score,HBV-DNA quantitative,laminin(LN),Ⅳ-collagen(Ⅳ-C),hyaluronic acid(HA),mean flow velocity of main portal vein(v),and internal diameter of portal vein(D)were compared and observed in the two groups before and after 6 months treatment.ResultsAfter treatment,ALT,AST,Alb,TBil,LN,Ⅳ-C,HA,Child-Push score,and HBV-DNA quantitative were significantly better than those before treatment(P＜0.05).Alb,Child-Pugh score,LN,Ⅳ-C,and HA in the observation group were all better than those in the control group after therapy(P＜0.05).There was no great difference in improvement of mean flow velocity of main portal vein(v),and internal diameter of portal vein(D)in the control group compared with that before(P＞0.05).In the observation group,the improvement of mean flow velocity of main portal vein(v)was better than that before with a statistical difference.Meanwhile,internal diameter of portal vein(D)in the observation group after therapy was greatly improved but without statistical significance(P＞0.05).ConclusionEntecavir treating liver cirrhosis of hepatitis B can swiftly inhibit viral replication and decrease the amount of hepatitis B virus in peripheral blood,and restore the liver function to normal.Entecavir combined with Fuzheng Huayu Capsules can reduce Child-Pugh score,increase Alb level,and improve liver fibrosis indexes and portal vein hemodynamics.
2017 Vol. 24 (35): 147-149转152 [
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166
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Effect observation of Chinese herbal aerosol inhalation treating chronic obstructive pulmonary disease
WANG Jun-shan； CHEN Ci-huan
ObjectiveTo observe the clinical effect of Chinese herbal aerosol inhalation treating chronic obstructive pulmonary disease.MethodsEighty patients with chronic obstructive pulmonary disease treated in the Second Department of Internal Medicine in Xinning Hospital of Traditional Chinese Medicine from January 2015 to January 2017 were randomly divided into the observation group(n=40)and control group(n=40).The two groups were given the conventional respiratory medicine treatment.The observation group was treated with Chinese herbal aerosol inhalation additionally.After 2 weeks treatment,the clinical curative effect between the two groups was compared.ResultsThe total effective rate was 95.0%in the observation group,which was obviously higher than that in the control group (P＜0.05).ConclusionChinese herbal aerosol inhalation therapy has definite clinical effect in the treatment of chronic obstructive pulmonary disease and can effectively improve the clinical symptoms of patients.It is worthy of clinical promotion.
2017 Vol. 24 (35): 150-152 [
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168
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153
Effect evaluation of Rue Huanong Decoction auxiliarily western medicine basic treatment treating acute suppurative tonsillitis
XIAO Jie ；HU Dan-xia ；LI Si-hong
ObjectiveTo investigate the clinical effect of Rue Huanong Decoction auxiliarily western medicine basic treatment treating acute suppurative tonsillitis.Methods60 patients with acute suppurative tonsillitis treated in our hospital from August 2016 to August 2017 were selected and they were divided into the two groups according to the random number table method,and there were 30 cases in each group.The control group was given western medicine basis treatment,while the study group was given western medicine basis treatment combined with Rue Huanong Decoction.The changes of clinical primary and secondary symptoms before and after intervention and clinical efficacy between the two groups were compared.ResultsThe improvement of the primary and secondary symptoms in the study group was significantly better than that in the control group (P＜0.05).The total score of primary and secondary symptoms in the study group were significantly lower than those in the control group (P＜0.05).The total effective rate of the study group(93.33%)was significantly higher than that of the control group(73.33%)(P＜0.05).ConclusionRue Huanong Decoction auxiliarily western medicine basic treatment treating acute suppurative tonsillitis can significantly improve the primary and secondary clinical symptoms of patients,with the exact curative effect and a certain safety,it is worthy of promotion and application.
2017 Vol. 24 (35): 153-155 [
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169
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Diagnostic significance of bone marrow morphology combined with peripheral blood smear examination in pancytopenia
LIANG Ye-ling；OU Wang-ling；CHEN Ping-xi；YANG Han-cai
ObjectiveTo investigate the significance of bone marrow morphology combined with peripheral blood smear examination in the diagnosis of pancytopenia.MethodsA total of 135 patients with hematopoietic diseases who were admitted to our hospital from January 2010 to June 2017 were selected.According to the type of hemocytopenia,the patients were divided into group A(n=60,non-pancytopenia)and group B(n=75,pancytopenia).Two groups of patients were all given routine examination of peripheral blood and bone marrow morphological examination.The levels of platelet(PLT),erythrocyte(RBC),leukocyte(WBC),hemoglobin(Hb),average hemoglobin concentration(MCHC),erythrocyte parametersaverage volume of red blood cells(MCV),and blood smear test results were statistically collected in both groups,and the diagnostic value of bone marrow morphology combined with peripheral blood smear examination in pancytopenia was analyzed.ResultsThe levels of PLT,RBC,WBC cell and Hb in group A were all higher than those in group B(P＜0.05).There were 5 cases of metastatic tumors in group A,7 cases of myelodysplastic syndromes,19 cases of splenic hyperthyroidism,and 29 cases of megaloblastic anemia.There were 44 cases of aplastic anemia in group B,and 31 cases of acute leukemia.The bone marrow morphology were accompanied by varying degrees of changes in both groups.The results of blood smear of hypersplenism in group A were significantly lower than those of metastatic tumor and myelodysplastic syndrome(P＜0.05);the results of blood smear of aplastic anemia in group B were lower than those of acute leukemia (P＜0.05);there were no statistically significant differences in the MCH hemoglobin and MCV between different diseases in group A and group B (P＞0.05).ConclusionBone marrow morphology combined with peripheral blood smear examination used for pancytopenia has an ideal effect,which can improve the clinical diagnosis rate and is worthy to be popularized and applied.
2017 Vol. 24 (35): 156-158转161 [
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170
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Changes of levels of ESAT-6 and IL-10 before and after the treatment of tubercular meningitis and its significance
GUO Xiao-dan ；LV Yong-nian ；LI Qiu-juan ；WANG Xiao-hua
ObjectiveTo explore the changes of levels of ESAT-6 and IL-10 before and after the treatment of tubercular meningitis and its clinical significance.Methods52 patients with tubercular meningitis who were admitted to our hospital from March 2014 to March 2016 were selected as the observation group,and 33 patients without tubercular meningitis who were admitted to our hospital during the same period of time were selected as the control group.The changes of levels of ESAT-6 and IL-10 before and after the treatment were compared and analyzed between the two groups.ResultsThe levels of ESAT-6 and IL-10 before the treatment in the observation group were significantly higher than those in the control group(P＜0.05).After treatment,the levels of ESAT-6 and IL-10 in the observation group were significantly lower than those before treatment,and the differences with in the group were statistically significant(P＜0.05).After treatment,the levels of ESAT-6 and IL-10 in the observation group were significantly higher than those in the control group,and the differences were statistically significant(P＜0.05).The differences of the levels of ESAT-6 and IL-10 in the control group before and after the treatment were not statistically significant(P＞0.05).ConclusionThe detection of ESAT-6 and IL-10 levels can evaluate the severity of disease for the patients with tubercular meningitis,which plays a guiding significance in formulating effective intervention measures and evaluating clinical efficacy.
2017 Vol. 24 (35): 159-161 [
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152
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Study on the change of antioxidation and protein metabolism of patients with polycystic ovary syndrome
YUAN Ying-jiu ；HOU Jian-liDING； Wen-qing
ObjectiveTo study and observe the change status of antioxidation and protein metabolism of patients with polycystic ovary syndrome (PCOS).Methods70 patients with PCOS in our hospital from October 2016 to June 2017 were selected as the observation group,70 healthy women with the same age at the same time were selected as the control group.Then the antioxidation and protein metabolism indexes of two groups were detected,and the detection results of two groups were compared,the detection results of observation group with different severity degree of PCOS were compared too,and the relationship between those detection indexes and PCOS were analyzed by the Logistic regression analysis.ResultsThe serum protein metabolism indexes and MDA of observation group were all higher than those of control group(P＜0.05),other serum antioxidation indexes were lower than those of control group(P＜0.05),the detection results of observation group with different severity degree of PCOS were compared,there were significant differences(P＜0.05),and the results of Logistic regression analysis showed，those detection indexes all had close relationship to PCOS,the difference was statistically significant(P＜0.05).ConclusionThe antioxidation and protein metabolism of patients with PCOS are obviously different to the results of healthy women with the same age,and those indexes all have close relationship to PCOS，and they can be as the guidance indexes of the disease.
2017 Vol. 24 (35): 162-164 [
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146
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Effect of serum homocysteine in the severity and diagnosis of patients with hypertension
YANG Cui-xiang
ObjectiveTo investigate the effect of serum homocysteine (Hcy)on the severity and diagnosof patients with hypertension.Methods150 cases of hypertension patients in our hospital from January 2016 to June 2017 were selected as the research group of this study,according to the blood pressure level divided into the research group 1 (grade 1 hypertension),the research group 2 (grade 2 hypertension),the research group 3 (grade 3 hypertension).In addition,100 healthy people in our hospital during the same period were selected as the control group of the study,the levels of serum Hcy in each group was compared.ResultsThe serum Hcy level of the study group was significantly higher than that of the control group,the difference was statistically significant(P＜0.05).Serum Hcy levels in the research group 2 were significantly higher than those in the research group 1,the difference was statistically significant(P＜0.05).Serum Hcy levels in the research group 3 were significantly higher than those in the research group 2 and those in the research group 1,the difference was statistically significant(P＜0.05).The proportion of high Hcy patients in the study group was significantly higher than that in the control group,the difference was statistically significant(P＜0.05).The proportion of the research group 2 of patients with high Hcy blood pressure was significantly higher than that of the research group 1,the difference was statistically significant(P＜0.05).The proportion of the research group 3 of patients with high Hcy blood pressure was significantly higher than that of the research group 1 and the research group 2,the difference was statistically significant(P＜0.05).ConclusionThe level of serum Hcy in patients with hypertension are significantly higher than those of healthy subjects,and with the increased level of blood pressure,serum Hcy level in patients with higher risk of high Hcy hyperlipidemia is bigger,so the serum Hcy can be used for patients with hypertension severity and diagnosis.
2017 Vol. 24 (35): 165-167 [
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202
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Influence of optimization of obstetric outpatient service process on the visiting time and satisfaction degree of pregnant women
FANG Shao
ObjectiveTo explore the optimization of obstetric outpatient service process on the visiting time and satisfaction of pregnant women.MethodsFrom December 2015 to December 2016,a total of 200 pregnant women in our hospital were investigated by questionnaire according to the admission order.100 pregnant women who did not optimize the process of obstetric outpatient service from December 2015 to June 2016 were selected as the control group,100 pregnant women after optimizing the obstetric outpatient service process from June to December in 2016 were selected as the observation group.The questionnaire survey in the two groups were analyzed.The average visiting time and nursing total satisfaction of the two groups of pregnant women were compared.ResultsThe average visiting time of the pregnant women in the observation group was(23.52±10.83)min,which was lower than(45.81±12.01)min in the control group,with significant difference(P＜0.05).The nursing total satisfaction of the observation group was 94.00%,which was significantly higher than 32.00%of the control group,with significant difference (P＜0.05).ConclusionObstetric outpatient service process optimization has important meaning in reducing visiting time of pregnant women and improving satisfaction of pregnant women,which can effectively improve the visiting effect,reduce the complaint rate of pregnant women in outpatient service.It is beneficial to establish a good relationship between nurses and patients,establish a good social image and is worth recommendation.
2017 Vol. 24 (35): 168-170 [
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Thinking of the ethical protection in clinical trial for orphan drugs
ZHANG Ai-li；LI Jing ；LI Yi ；HE Wen-ji；PANG Xue-jing ；TAO Na；WANG Mei-fen；ZHANG Zhen；LI Cong-mei
Rare diseases are also known as orphan diseases,so drugs for rare diseases are also called orphan drugs.Drugs clinical trial is the prerequisite to the research of orphan drugs before they appear on the market.In view of the pathological characteristics of rare diseases patients and the inaccessibility of orphan drugs in China,ethical review is an important means to protect the rights and interests of subjects involved in drug clinical trials as well as a moral guarantee to regulate the procedure of clinical trials for orphan drugs.This thesis explores the ethical protection of orphan drugs clinical trial in the fields of clinical trial protocol,information consent,and privacy protection,with a view to raising people′s awareness to the importance of ethical review of clinical trials for orphan drugs.
2017 Vol. 24 (35): 171-173 [
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Application effect of nursing risk safety management in cancer patients
YANG Zhi-ding
ObjectiveTo explore the clinical application effect of nursing safety management in cancer patients.Methods76 cancer patients from January 2015 to January 2017 when nursing safety management measures have been implemented were selected as observation group.40 cancer patients from January 2013 to January 2015 when nursing safety management measures have not been implemented were selected as control group.The clinical nursing data of two groups were analyzed retrospectively.The incidence of clinical risk and nursing satisfaction were compared between the two groups.ResultsAmong the 76 patients in the observation group,there were 17 cases with nursing risk,and the incidence of nursing risk was 22.37%,and among the 40 patients in the control group,there were 18 cases with nursing risk,and the incidence of nursing risk was 42.5%,the incidence of nursing risk in the observation group was significantly lower than that in the control group,the difference was statistically significant(P＜0.05).The nursing satisfaction degree in the observation group was 90.79%,which was higher than that was 72.5%in the control group,and the difference was statistically significant(P＜0.05).ConclusionAfter the implementation of nursing safety management measures,the incidence of clinical nursing risk decreased significantly,and the patients′satisfaction was improved,which shows that the application of nursing safety management can effectively improve the quality of clinical nursing,and is worth popularizing and applying widely in clinic.
2017 Vol. 24 (35): 174-176 [
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Application of nursing risk management model in hospitalized psychotic patients
TAN Yi-xin
ObjectiveTo explore the application of nursing risk management model in hospitalized psychotic patients.MethodsFrom June 2014 to December 2016,82 cases of hospitalized psychiatric patients in our hospital were selected as the objects of study,and according to different nursing management modes divided into routine group and observation group,41 cases in each group.The routine nursing management mode was adopted in the conventional group,and the observation group was treated with the nursing risk management mode.The accident situation and nursing satisfaction of the two groups were observed.ResultsIn the observation group,the incidence rate of accidents(4.88%)was lower than the conventional group (19.51%),the difference was statistically significant(P＜0.05).In the observation group,the death rate(0.00%)was lower than the conventional group(9.76%),the difference was statistically significant(P＜0.05).Nursing satisfaction rate of the observation group(95.12%)was higher than that of the conventional group(78.05%),with statistically significant difference(P＜0.05).ConclusionThe implementation of nursing risk management in hospitalized psychiatric patients can reduce the incidence of accidents and improve the quality of nursing staff,so as to improve the satisfaction of patients,and is worthy of clinical application.
2017 Vol. 24 (35): 177-179 [
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168
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Application effect of humanistic nursing in AIDS patients
WEI Mei-yun；CHEN Wen-min
ObjectiveTo explore the application effect of humanistic nursing in AIDS patients.Methods50 cases of AIDS patients treated in our hospital from January 2016 to July 2017 were selected as the subjects,and randomly divided into control group (routine nursing mode)and observation group (humanistic nursing mode),the effect of nursing in the two groups were compared.ResultsAfter the treatment,the anxiety and depressive symptoms of patients in the two groups were improved in different level,the anxiety and depression scores in the observation group were significantly lower than those in the control group (P＜0.05).The satisfaction of the patients in the observation group (96.00%)was higher than that in the control group(76.00%),the difference was statistically significant(χ2=4.153,P＜0.05).ConclusionAIDS patients in the clinical nursing process with the application of humanistic care can improve the patient′s anxiety,depression and nursing satisfaction.
2017 Vol. 24 (35): 180-182 [
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154
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Application effect of high quality nursing service in patients with chronic pelvic inflammatory disease
CHENG Li；LUO Gui-fen
ObjectiveTo explore the application effect of high quality nursing service in patients with chronic pelvic inflammatory disease(PID).MethodsFrom April 2015 to April 2016,96 patients with chronic PID treated in our hospital were randomly divided into control group and observation group,48 cases in each group.In the control group,routine nursing was used,while in the observation group,high quality nursing service was adopted.The clinical effect,quality of life score,SAS and SDS scores and recurrence rate after intervention in the two groups were compared.ResultsThe total effectiveness rate in the observation group (95.83%)was higher than that in the control group (83.33%),the difference was statistically significant(P＜0.05).After the intervention,the scores of quality of life,SAS,and SDS were significantly lower than those of before the intervention.These indexes in the observation group were better than those in the control group,the difference was statistically significant(P＜0.05).The recurrence rates 6 months and 1 year after intervention in the observation group was lower than those in the control group,the difference was statistically significant(P＜0.05).ConclusionFor patients with chronic PID,application of high quality nursing service can obtain a remarkable clinical effect by effectively improving the quality of life and unhealthy emotions,which has an important application value.
2017 Vol. 24 (35): 183-185 [
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170
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The application effect of comprehensive nursing intervention in elderly patients with hip fracture
YE Hong-yan
ObjectiveTo explore the application effect of comprehensive nursing intervention in elderly patients with hip fracture.Methods90 elderly patients with hip fracture treated in our department from June 2015 to June 2017 were selected as the research objects,and randomly divided into the control group and the observation group,45 cases in each group.The control group was treated with traditional nursing intervention,and the observation group was treated with comprehensive nursing intervention.The scores of self-efficacy(GSES),anxiety state(SAS)and complications were compared between the two groups before and after nursing intervention.ResultsThere was no significant difference in SAS and GSES scores before nursing intervention between the two groups(P＞0.05).After nursing intervention,the SAS score of the observation group was significantly lower than that of the control group,and the GSES score was significantly higher than that of the control group,the differences were statistically significant(P＜0.05).The incidence of complications in the observation group was 4.44%,which was significantly lower than 22.22%in the control group,the difference was statistically significant(P＜0.05).ConclusionThe application of comprehensive nursing intervention can effectively reduce the anxiety degree of elderly patients with hip fracture,improve the patient′s self-efficacy,reduce the probability of complications,which is worthy of promotion.
2017 Vol. 24 (35): 186-188 [
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185
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Application effect of evidence-based nursing combined with clinical nursing pathway in the orthopedic nursing care
RONG Qin；ZHANG Chun-quan
ObjectiveTo explore the application effect of evidence-based nursing combined with clinical nursing pathway in the orthopedic nursing care.Methods120 patients in the department of orthopedics who were admitted to our hospital from January 2016 to December 2016 were selected and randomly divided into the observation group and the control group,with 60 patients in each group.The patients in the control group were given routine nursing method,and the observation group was given evidence-based nursing combined with clinical nursing pathway for nursing care.The clinical efficacy,cognitive level,anxiety level,nursing satisfaction,length of stay and clinical benefit ratio were observed and compared between the two groups.ResultsThe clinical effective rate(96.67%)in the observation group was significantly higher than that in the control group(86.67%),and the difference was statistically significant(P＜0.05).The degree of anxiety in the observation group was significantly lower than that in the control group,the cognitive level was significantly higher than that in the control group,and the differences were statistically significant(P＜0.05).The nursing satisfaction in the observation group(95.00%)was significantly higher than that in the control group(76.67%),the difference was statistically significant(P＜0.05).The length of stay in the observation group was significantly shorter than that in the control group,the cost was significantly lower than that in the control group,and the benefit ratio in the observation group was better than that in the control group,the differences were statistically significant(P＜0.05).ConclusionEvidence-based nursing combined with clinical nursing pathway in orthopedic nursing care can improve clinical efficacy,nursing satisfaction and the prognosis of patients,with a better clinical benefit ratio,which is worthy of clinical promotion and application.
2017 Vol. 24 (35): 189-191 [
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Application effect of detail nursing in operation room for surgical patients
XIAO Yan
ObjectiveTo investigate the effect of detail nursing in operation room for surgical patients.MethodsFrom March 2015 to July 2016,98 cases of surgery patients in our hospital were selected as the research objects,randomly divided into details group(49 cases)and routine group(49 cases).The details group was given detail nursing in operation room,the routine group was given routine nursing in operation room.The operation safety score,length of stay,nursing satisfaction and complication rate were compared between the two groups.ResultsThe safety score of nursing in the operation room was higher than that in the routine group,and the hospitalization time in the detail group was shorter than that in the routine group,the differences were statistically significant(P＜0.05).The total complication rate in detail group(10.20%)was lower than that in routine group(28.57%),the differences were statistically significant(P＜0.05).The satisfaction rate of detail group(93.88%)was higher than that of routine group(71.43%),the difference was statistically significant(P＜0.05).ConclusionDetails nursing can improve the safety of operation room and patient care satisfaction,reduce the incidence of postoperative complications,shorten the patient′s hospital stay,the clinical application effect is good,which is worthy of popularizing.
2017 Vol. 24 (35): 192-194 [
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Study on preparation and cooperation of CT room care
FAN Jing
ObjectiveTo explore the effective preparation and cooperation of CT room care.Methods90 patients treated in the CT room of our hospital from March 2015 to March 2017 was selected as the subjects,randomly divided into the control group and the observation group,45 cases in each group.The control group was treated with routine nursing,and the observation group was treated with comprehensive nursing.The nursing satisfaction,CT examination pass rate and nursing quality were compared between the two groups.ResultsThe satisfaction rate of care,the qualified rate of CT examination and the quality of care were higher than those in the observation group,the differences were statistically significant(P＜0.05).ConclusionThe patients in CT room with comprehensive care can effectively improve the CT examination of the pass rate and the quality of care,the clinical application value is better,which is worthy of learning and promotion.
2017 Vol. 24 (35): 195-197 [
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