荆花胃康胶丸联合四联疗法治疗消化性溃疡伴Hp感染的临床效果

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Abstract ObjectiveTo investigate the clinical effect of Jinghua Weikang Gelatin Pearls combined with quadruple therapy in the treatment of peptic ulcer complicated with Helicobacter pylori(Hp)infection.Methods123 patients with peptic ulcer complicated with Hp infection treated in our outpatient clinic and inpatient wards from August 2014 to May 2017 were divided into the three groups using the complete random method.In the control group A,regimen of standard quadruple therapy was used for 14 days.In the experimental group B,the standard quadruple therapy was continued for 14 days,and Jinghua Weikang Gelatin Pearls was used for another 18 days.In the experimental group C,Jinghua Weikang Gelatin Pearls was firstly used for 18 days,followed by 14-day standard quadruple therapy.Hp eradication rate,clinical symptomatic improvement,and ulcer healing under endoscope were calculated and analyzed among three groups.ResultsThe total effective rate of patients in the experimental group B and C was significantly higher than that in the control group A,and the difference was statistically significant(P＜0.05),the total effective rate in the experimental group C was higher than that in the experimental group B,with a statistically significant difference (P＜0.05).In control group A,Hp eradication rate of the control A was 63.41%,and it was 85.37%in the experimental group B,and it was 87.80%in the experimental group C,and Hp eradication rate of patients in the experimental group B and C was significantly higher than that in the control group A,and the difference was statistically significant(P＜0.05),and there was no statistical difference of Hp eradication rate between the experimental group B and C(P＞0.05).There was no significant difference of ulcer healing under endoscope among the three groups(P＞0.05).ConclusionHp eradication rate and the role of improving the clinical symptoms in patients of Jinghua Weikang Gelatin Pearls combined with quadruple therapy obtain more remarkable effect compared with only quadruple therapy.Jinghua Weikang Gelatin Pearls followed by quadruple therapy is more beneficial of improving clinical symptoms.

Key words： Helicobacter pylori Jinghua Weikang Gelatin Pearls Quadruple therapy Peptic ulcer Clinical effect

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	Articles by authors
	GU Jing
	ZHANG Guo-bao
	GENG Chang-hai

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GU Jing,ZHANG Guo-bao,GENG Chang-hai. Clinical effect of Jinghua Weikang Gelatin Pearls combined with quadruple therapy in the treatment of peptic ulcer complicated with Hp infection[J]. 中国当代医药, 2017, 24(35): 12-14.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I35/12

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