多囊卵巢综合征患者抗氧化及蛋白代谢的变化研究

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Abstract ObjectiveTo study and observe the change status of antioxidation and protein metabolism of patients with polycystic ovary syndrome (PCOS).Methods70 patients with PCOS in our hospital from October 2016 to June 2017 were selected as the observation group,70 healthy women with the same age at the same time were selected as the control group.Then the antioxidation and protein metabolism indexes of two groups were detected,and the detection results of two groups were compared,the detection results of observation group with different severity degree of PCOS were compared too,and the relationship between those detection indexes and PCOS were analyzed by the Logistic regression analysis.ResultsThe serum protein metabolism indexes and MDA of observation group were all higher than those of control group(P＜0.05),other serum antioxidation indexes were lower than those of control group(P＜0.05),the detection results of observation group with different severity degree of PCOS were compared,there were significant differences(P＜0.05),and the results of Logistic regression analysis showed，those detection indexes all had close relationship to PCOS,the difference was statistically significant(P＜0.05).ConclusionThe antioxidation and protein metabolism of patients with PCOS are obviously different to the results of healthy women with the same age,and those indexes all have close relationship to PCOS，and they can be as the guidance indexes of the disease.

Key words： Polycystic ovary syndrome Antioxidation indexes Protein metabolism indexes

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	YUAN Ying-jiu
	HOU Jian-liDING
	Wen-qing

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YUAN Ying-jiu,HOU Jian-liDING,Wen-qing. Study on the change of antioxidation and protein metabolism of patients with polycystic ovary syndrome[J]. 中国当代医药, 2017, 24(35): 162-164.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I35/162

[1]	李扬璐，阮祥燕，崔亚美，等.四种血清脂蛋白比值对多囊卵巢综合征患者发生代谢综合征的诊断预测价值[J].首都医科大学学报，2015，36（4）:559-566.
[2]	张文龙，李启富，杨淑敏，等.重庆地区汉族人群多囊卵巢综合征与葡萄糖激酶调节蛋白基因多态性的相关性研究[J].重庆医科大学学报，2014，39（9）:1329-1333.
[3]	张喜梅，马国芳.克罗米芬联合二甲双胍对多囊卵巢综合征患者外周血T细胞亚群及氧化应激水平的影响[J].山东医药，2017，57（12）:88-90.
[4]	涂铵素，钟影，毛熙光.多囊卵巢综合征合并不孕症患者血清TOS，TAS水平变化及其与血浆载脂蛋白（a）的关系[J].南方医科大学学报，2016，36（3）:405-409.
[5]	李艳秋，王颖，侯丽辉.多囊卵巢综合征载脂蛋白B/载脂蛋白 A1 比值的研究进展[J].医学研究杂志，2015，44（4）:15-17，21.
[6]	崔馨月，侯丽辉，郝松莉，等.多囊卵巢综合征脂代谢、氧化应激与动脉粥样硬化的关系[J].医学研究杂志，2014，43（5）:12-14.
[7]	郑国华，王爱婷，李文欣，等.多囊卵巢综合征不孕症患者血清睾酮水平变化及与机体氧化应激的关系[J].山东医药，2015，55（11）:55-56.
[8]	Turan V，Sezer ED，Zeybek B，et al.Infertility and the presence of insulin resistance are associated with increased oxidative stress in young，non-obese Turkish women with polycystic ovary syndrome[J].J Pediatr Adolesc Gynecol，2015，28（2）:119-123.
[9]	Enli Y，Fenkci SM，Fenkci V，et al.Serum Fetuin-A levels，insulin resistance and oxidative stress in women with polycystic ovary syndrome[J].Gynecol Endocrinol，2013，29（12）:1036-1039.
[10]	梅玲蔚，熊正爱.氧化应激与多囊卵巢综合征的研究进展[J].广东医学，2014，35（8）:1282-1284.
[11]	李文静，胡红波，马占忠，等.多囊卵巢综合征患者不同分型的酶类抗氧化应激状况分析[J].广东医学，2016，37（16）:2431-2433.
[12]	梁莹，田茜华，穆玉霞，等.苍附苁仙汤对多囊卵巢综合征氧化应激的影响[J].中国中西医结合杂志，2016，36（6）:685-689.
[13]	刘忠慧，黄鑫，郝翠芳.氧化应激对多囊卵巢综合征患者体外受精-胚胎移植结局的影响[J].生殖医学杂志，2014，23（12）:976-980.
[14]	孙林，王海燕，邵小光.PCOS患者血清ROS及TAC与IVF结局的相关性研究[J].中华临床医师杂志（电子版），2016，10（11）:41-42.
[15]	龚晋，吴东波，张兰兰，等.PCO模型大鼠卵巢组织氧化应激水平的研究[J].四川大学学报（医学版），2015，46（2）:238-242.