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Effect of serum homocysteine in the severity and diagnosis of patients with hypertension |
YANG Cui-xiang |
Department of Clinical Laboratory,Hualong Hospital of Panyu District of Guangzhou City in Guangdong Province,Guangzhou 511434,China |
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Abstract ObjectiveTo investigate the effect of serum homocysteine (Hcy)on the severity and diagnosof patients with hypertension.Methods150 cases of hypertension patients in our hospital from January 2016 to June 2017 were selected as the research group of this study,according to the blood pressure level divided into the research group 1 (grade 1 hypertension),the research group 2 (grade 2 hypertension),the research group 3 (grade 3 hypertension).In addition,100 healthy people in our hospital during the same period were selected as the control group of the study,the levels of serum Hcy in each group was compared.ResultsThe serum Hcy level of the study group was significantly higher than that of the control group,the difference was statistically significant(P<0.05).Serum Hcy levels in the research group 2 were significantly higher than those in the research group 1,the difference was statistically significant(P<0.05).Serum Hcy levels in the research group 3 were significantly higher than those in the research group 2 and those in the research group 1,the difference was statistically significant(P<0.05).The proportion of high Hcy patients in the study group was significantly higher than that in the control group,the difference was statistically significant(P<0.05).The proportion of the research group 2 of patients with high Hcy blood pressure was significantly higher than that of the research group 1,the difference was statistically significant(P<0.05).The proportion of the research group 3 of patients with high Hcy blood pressure was significantly higher than that of the research group 1 and the research group 2,the difference was statistically significant(P<0.05).ConclusionThe level of serum Hcy in patients with hypertension are significantly higher than those of healthy subjects,and with the increased level of blood pressure,serum Hcy level in patients with higher risk of high Hcy hyperlipidemia is bigger,so the serum Hcy can be used for patients with hypertension severity and diagnosis.
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