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2018 Vol. 25, No. 22
Published: 2018-08-08
4
Regulation of Oxytocin on feeding in the amygdaloid nucleus
ZHU Yong-xiang;WANG Qian;XU Yan;YU Wei;NAN Ying;CAO Jian
Objective
To observe the regulation of Oxytocin (OT)on feeding in the amygdaloid nucleus.
Methods
Forty-eight male Sprague-Dawley(SD)rats were selected.Among them,16 rats were randomly divided into free-feeding group and 72-hour fasted group,with 8 in each group.Immunohistochemistry was used to detect the expression of OT receptors in the rat amygdala.The remaining 32 rats were subjected to cannula implantation in amygdala and 16 of them were randomly divided into two groups,namely the injected with OT in amygdaloid nucleus group and the injected with normal saline in amygdaloid group 1 respectively,8 rats in each group.Food intake was measured in rats at 0.5,1,2,and 3 h.Another 16 postoperative rats were randomly divided into two groups,namely the injected with OT receptor blocker(Atosiban)in amygdaloid nucleus group and the injected with normal saline in amygdaloid group 2 respectively,8 rats in each group.Similarly,food intake of the rats was measured at 0.5,1,2,and 3 h.
Results
The expression of OT receptors in the amygdaloid nucleus of rats in the 72-hour fasted group was significantly higher than that in the normal feeding group,and the difference was statistically significant(P<0.05).The food intake of rats of injected with OT in amygdaloid nucleus group at 0.5,1,2,and 3 h were lower than those in the injected with normal saline in amygdaloid group 1,and the differences were statistically significant(P<0.05).The food intake of rats of injected with Atosiban in amygdaloid nucleus group at 0.5,1,2,and 3 h were higher than those in the injected with normal saline in amygdaloid group 2,and the differences were statistically significant(P<0.05).
Conclusion
OT participates in feeding regulation in the amygdaloid nucleus through acting on its receptors.
2018 Vol. 25 (22): 4-7 [
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182
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8
Application effect of treatment mode of combination of medical treatment and pension in elderly patients with multiple myeloma
JIANG Zu-jun;WANG Mei-xiu;XU Xiang-min;LIANG Wei-ping;LIU Zeng-hui;ZOU Tao;GAO Huarong;LIN Liang-hong
Objective
To investigate the application effect of treatment mode of combination of medical treatment and pension in elderly patients with multiple myeloma.
Methods
A total of 62 elderly patients with multiple myeloma treated in our department from January 2015 to December 2017 were selected.The patients were divided into the control group(n=31)and observation group(n=31)according to the random number table method.Patients in the control group were given the routine treatment and nursing,while patients in the observation group were given treatment mode of combination of medical treatment and pension.The incidence of complications,quality of life and nursing satisfaction degree in patients between the two groups were compared.
Results
The total incidence of complications in the observation group was significantly lower than that in the control group(P<0.05).Each score of quality of life in patients of the observation group patients after 3 months intervention was significantly higher than that of the control group respectively(P<0.05).The nursing satisfaction degree score of patients in the observation group was significantly higher than that in the control group (P<0.05).
Conclusion
The treatment mode of combination of medical treatment and pension applied in elderly patients with multiple myeloma can improve the quality of life and nursing satisfaction degree of patients,and has a high application value.
2018 Vol. 25 (22): 8-10转16 [
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196
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11
Analysis of blood concentration of Cyclosporine A in patients after hematopoietic stem cell transplantation
TIAN Ji-xin;ZHANG Ping;WANG Xiao-dan;LIAO Ying-xi;LI Shan;YAN Hai-hong
Objective
To retrospectively analyze the distribution of blood concentration of Cyclosporine A(CsA)in patients after allogeneic hematopoietic stem cell transplantation(alloHSCT)and to investigate its relationship with the incidence of renal dysfunction.
Methods
From January 2015 to September 2016,clinical data of 110 patients who underwent alloHSCT and received CsA in our hospital were retrospectively collected.Intravenous infusion blood concentration(Cv),oral administration of valley(C
0
),peak concentration(C
2
)distribution range of patients were analyzed,and the incidence of progressive increase in serum creatinine values in different blood concentrations was counted,so as to explore the relationship between CsA and the incidence of renal dysfunction.
Results
After analysis,the distribution of mean blood concentration in patients with early application of CsA to prevent graft-versus-host diseases after alloHSCT was as follows∶85.45%of Cv was distributed in the range of 250-400 ng/ml,68.00%of C
0
in the range of 100-300 ng/ml,and 71.00%of C
2
in the range of 300-700 ng/ml.According to statistics,the incidence of serum creatinine values increased>50%by CsA was 37.27%,of which 87.80%occurred during oral administration.There were significant differences in the average values of C
0
,C
2
and Cv of CsA in the non-renal dysfunction group and the renal dysfunction group (P<0.05).With the increase of average Cv,C
0
,and C
2
values,the incidence of progressive increases in the incidence of serum creatinine values increased>50%was significantly higher.
Conclusion
The nephrotoxicity of CsA may have an exposure/time cumulative effect.The situation of Cv≤300 ng/ml,C
0
≤200 ng/ml and C
2
≤400 ng/ml could significantly reduce the occurrence of renal dysfunction.
2018 Vol. 25 (22): 11-16 [
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179
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17
Clinical effect of percutaneous pedicle screw internal fixation assisted by metal grid in the treatment of thoracolumbar fractures
GAO Li-bo;LI Gui-jun;AN Jin-yu;WEN Hui-long;HU Hui-dong;WU Yi-xiong
Objective
To observe the clinical effect of metal grid assisted percutaneous pedicle screw internal fixation in the treatment of thoracolumbar fractures.
Methods
From June 2013 to August 2017,25 patients with complete follow-up data of thoracolumbar fractures treated with metal grid assisted pedicle screw fixation were selected.The Cobb angle,vertebral height ratio and VAS score were observed before and after operation,and the efficacy of all patients was evaluated according to the modified Macanb standard.
Results
The Cobb angle,VAS score and vertebral body height ratio of 25 patients were significantly improved after operation,compared with before operation (P<0.01).The modified Macanb standard was excellent in 15 cases,good in 8 cases,fair in 2 cases and poor in 0 cases.The excellent and good rate was 92%.
Conclusion
The metal grid assisted percutaneous pedicle screw internal fixation simplifies the operation,and the treatment effect is satisfactory,which is worthy of clinical promotion.
2018 Vol. 25 (22): 17-20 [
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178
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21
Effect of arthroscopy-assisted minimally invasive technique in the treatment of tibial plateau fractures
WU Xiu-dong;DENG Gang-qiang;LI Wen-hua;YANG Xiao-zhen;HUANG Chun-yan
Objective
To explore the effect of arthroscopy-assisted minimally invasive technique in the treatment of tibial plateau fractures.
Methods
A total of 64 patients with tibial plateau fractures who were admitted to our hospital from December 2011 to December 2015 were selected and randomly divided into the study group and the control group,32 cases in each group.The study group was given arthroscopy-assisted minimally invasive techniques.The control group was given traditional open surgical treatment.The incision length,operation time,intraoperative blood loss,incision healing time,incidence rate of postoperative complications and joint activity(HSS knee function score)were compared between the two groups.
Results
The incision length in the study group was shorter than that in the control group,the operation time and wound healing time were shorter than those in the control group,intraoperative blood loss was less than that in the control group,and the difference was statistically significant(P<0.05).The complication rate in the study group was 0.00%,which was lower than 31.25%in the control group,and the difference was statistically significant(P<0.05).The excellent and good rate of HSS scores in the study group was 93.8%,which was higher than that 71.9%in the control group,and the difference was statistically significant(P<0.05).
Conclusion
Arthroscopy-assisted minimally invasive technique in the treatment of tibial plateau fractures have the advantages of accurate reduction,less injury,rapid healing,better function recovery,and fewer complications.
2018 Vol. 25 (22): 21-24 [
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194
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25
Effect comparison of femoral neck compression locking bone plate and cannulated compression screw in the treatment of young femoral neck fracture
ZHANG Gong;LI Song-jun;DONG Jie
Objective
To compare the effects of femoral neck compression locking bone plate and cannulated compression screw in the treatment of young femoral neck fracture.
Methods
A total of 60 cases of young femoral neck fractures undergoing surgeries from January 2013 to March 2016 in the Fifth Afiliated Hospital of Zunyi Medical College(Zhuhai)were selected and divided into the observation group(34 patients)and the control group(26 patients)according to their surgical intention.The observation group was treated with femoral neck compression locking bone plate,the control group was treated with cannulated compression screw.The operative time,intraoperative bleeding volume,fracture healing time,the postoperative hip joint function score (Harris hip score)after 6 months and 12 months,the incidence of postoperative complications were compared.
Results
The oprerative time in the observation group was longer than that in the control group,while the intraoperative bleeding volume in the observation group was more than that in the control group,with significant difference (P<0.05).The postoperative fracture healing time in the observation group was shorter than that in the control group,the Harris hip score for 6 months after surgery and the incidence of postoperative complications in the observation group were lower than that in the control group,with significant difference(P<0.05).There were no significant differences in Harris score between the two groups for 12 months after surgery (P>0.05).
Conclusion
Femoral neck compression locking plate in the treatment of youth femoral neck fracture can reduce fracture healing time,achieve early functional exercise and less complications.This technique is worthy of clinical application.
2018 Vol. 25 (22): 25-28 [
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172
)
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29
The application of diffusion weighted imaging in cervical cancer
WANG Xian;XIAO Ze-ming; YANG Mao-sheng
Cervical cancer(CC)is one of the most common malignant tumors in the female genital tract.For patients with early CC,surgical is the preferred treatment,and synchronous radiotherapy is often selected for patients in the middle and late stages.Diffusion weighted imaging (DWI)is an imaging method to observe the microscope motion of the living water molecules.It is of great significance in the diagnosis of CC,clinical staging,evaluation of curative effect and monitoring of recurrence as one of the common noninvasive methods.This article is a systematic review of the application of DWI in CC.It also points out the advantages and disadvantages.Expected to provide guidance for more accurate and individualized diagnosis and treatment programs for patients with CC.
2018 Vol. 25 (22): 29-31 [
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212
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32
Research progress on safe medication of home medication cabinets
YE Juan;XU Chun-mei; XUE Cheng-bin;YAN Qiong;GAN Fei;YANG Rui
With the improvement of people′s living standard and strengthening health concerns,the home medication cabinet is used widely in community families.But there are potential dangers of safe medication in the home medication cabinet,and irrational use of family medicines can easily cause adverse drug reactions and drug-induced diseases.Through reviewing reference literatures,analyze investigations on safe medication of the home medication cabinets in our country in the past 10 years.The study results can provide reference for pharmacists in designing management,consultation,and guidance of family safe medication.Pharmacists in community hospitals should play the role of pharmaceutical care so as to improve the level of safe medication of the home medication cabinets.
2018 Vol. 25 (22): 32-34转38 [
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190
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Clinical application of sublingual immunotherapy for allergic asthma
ZHONG Can
Sublingual immunotherapy(SLIT)is an important therapeutic route for allergic diseases in recent years,which clinical application is becoming more and more extensive.A large number of clinical studies confirm that SLIT has significant clinical effects on allergic asthma (AS).This article briefly reviews the clinical application status of SLIT for AS,including the clinical efficacy,the long-term effect,the preventive effect,the effect of single allergen on multiple allergies,the effect on special allergic asthma,the efficacy of different age groups and the safety of medication during pregnancy.
2018 Vol. 25 (22): 35-38 [
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39
Effect analysis of family contracted service on improving community selfmanagement ability of initial type 2 diabetes mellitus
HE Min-lan;XIE Yan-hua;WANG Wei-hua
Objective
To explore the effect evaluation of community family contracted service model on improving the self-management ability of newly diagnosed type 2 diabetic patients.
Methods
A total of 164 patients with newly diagnosed type 2 diabetes mellitus(DM)who were admitted to our hospital in Bao′an District,Shenzhen City from December 2015 to January 2017 were selected.They were grouped using a random number table method,82 cases in each group.In control group,routine instruction was provided,while in observation group,community family contracted service model as an intervention was adopted.The blood glucose,blood pressure,self-management ability such as scientific diet,regular exercise,medication following doctor′s advice,and blood glucose monitoring of the two groups were compared.
Results
After intervention,the blood sugar and blood pressure of the observation group were significantly lower than those of the control group with statistical significance (P<0.05).The scores of self-management ability such as scientific diet,regular exercise,medication following doctor′s advice,and blood glucose monitoring in the observation group were higher than those in the control group,with statistical significance(P<0.05).
Conclusion
Community family contracted service for patients with newly diagnosed type 2 DM can stabilize blood glucose and blood pressure and improve self-management ability,which is worthy further promotion and application.
2018 Vol. 25 (22): 39-41转50 [
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165
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42
Influence of Buchang Naoxintong on microinflammation markers and carotid intima-media thickness
LIANG Li-yan;LIAO Jian-jun;CHENG Yan-li
Objective
To investigate the effect of Buchang Naoxintong on microinflammation markers and carotid intima-media thickness.
Methods
The clinical data of 60 patients with maintenance hemodialysis(MHD)admitted to our hospital from August to December 2017 were analyzed.According to whether or not the patients were treated with Buchang Naoxintong,they were equally divided into control group (basic treatment)and observation group(Buchang Naoxintong treatment),30 cases in each group.The levels of interleukin-6(IL-6),C-reactive protein(CRP)and tumor necrosis factor-α (TNF-α),carotid intima-media thickness(IMT),maximum thickness(Tmax),and maximum area in transection (Smax)were observed before and after treatment in the two groups.
Results
There was no significant difference in the level of IL-6,CRP,TNF-α,IMT,Tmax or Smax between the two groups before treatment(P>0.05).After therapy,IL-6,CRP,and TNF-α levels,IMT,Tmax and Smax were all lower than those in the same group before treatment.After treatment,the levels of IL-6,CRP,TNF-α,IMT,Tmax,and Smax were all lower in the observation group compared with those in the control group with statistical significance(P<0.05).
Conclusion
The application of Buchang Naoxintong in patients with MHD can improve the inflammatory state and reduce the carotid intima-media thickness,which is worthy of clinical promotion.
2018 Vol. 25 (22): 42-44 [
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180
)
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45
Genetic analysis and biochemical index characteristics of neonatal intrahepatic cholestasis caused by citrin protein deficiency in Tujia minority in Zhangjiajie Area
ZHANG Wei;TIAN Chang-jun; WANG Hong-bo;LIU Fang-ping;QIN Da-wei
Objective
To investigate the mutation and biochemical characteristics of SLC25A13 gene in neonatal intrahepatic cholestasis caused by Citrin protein deficiency (NICCD)in Tujia minority in Zhangjiajie Area.
Methods
SLC25A13 gene mutation analysis was performed in children with idiopathic neonatal cholestasis(INC)admitted to the Department of Pediatrics in our Hospital from September 2014 to December 2016.The patients diagnosed with NICCD were classified into observation group.Pediatric patients randomly selected except for NICCD were assigned to control group.The differences in biochemical indicators between the two groups were compared.
Results
Among 85 pediatric patients performed with SLC25A13 gene mutation analysis,7 cases were diagnosed as NICCD.The SLC25A13 gene mutated for three mutations including 1851del4,IVS6+5G>A,and 1638ins23,of which the 1851del4 mutation accounted for 57.10%of the total mutations.The comparison of biochemical indicators showed that the total bile acid,gammaglutamyl transpeptidase,prothrombin time,and aspartate aminotransferase/alanine aminotransferase (AST/ALT)were higher in the observation group than in the control group,and the levels of ALT,AST,serum albumin,and BS were lower in the observation group than in the control group(P<0.05).
Conclusion
NICCD due to SLC25A13 gene mutation is one of the main causes for INC in Tujia minority in Zhangjiajie Area.The 1851del4 mutant is the most common type.Changes in biochemical markers in NICCD children are helpful for early identification of the disease.
2018 Vol. 25 (22): 45-47 [
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48
Effect of Antelope Particles in the treatment of infantile fever with seizures
ZHANG Mei-xia;HE Wei;ZHONG Ying-hua
Objective
To explore the effect of Antelope Horn Granule in the treatment and prevention of febrile convulsion in infants.
Methods
A total of 80 cases of febrile convulsion infants treated in our hospital from January 2016 to January 2017 were selected.They were randomly divided into observation group and control group by random number table method,40 cases in each group.The control group was given conventional treatment,and the observation group was treated with Antelope Horn Granules on the basis of the control group.Continuous treatment until the body temperature returned to normal after 24 h.The clinical efficacy,recurrence of febrile seizures,recovery time of body temperature,relapse of body temperature and incidence of adverse reactions were observed in two groups.
Results
The total effective rate of the observation group was 92.5%,significantly higher than 82.5%of the control group,the difference was statistically significant(P<0.05).The recurrence rate of the observation group was significantly lower than that in the control group,and the frequency of relapse was significantly lower than that in the control group (P<0.05).There was no significant difference in the incidence rate of adverse reaction between the two groups(P>0.05).
Conclusion
Antelope Horn Granule is effective in the treatment of febrile convulsion in infants.It can effectively reduce the recurrence rate of convulsion,and not increase the incidence of adverse reactions.It is worthy of clinical promotion.
2018 Vol. 25 (22): 48-50 [
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204
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51
Clinical effect of prone position ventilation for severe acute respiratory distress syndrome
XIAN Ling-jun;TANG Shao-xuan;TAN Qi-jia;YE Guo-hua
Objective
To investigate the effect of prone position ventilation for severe acute respiratory distress syndrome (ARDS).
Methods
A total of 48 patients with severe ARDS who were admitted to our Intensive Care Unit from June 2015 to August 2017 were selected.By a random number table method,they were equally divided into groups A and groups B.Another batch of 24 mild to moderate ARDS was selected as group C.Patients in group A and C were treated with prone position ventilation,while in group B,patients were treated with supine position ventilation.Hemodynamic parameters including heart rate (HR),cardiac index (CI),central venous pressure (CVP)and mean arterial pressure(MAP)between the groups A and B were compared.The levels of oxygenation index before and after treatment among the three groups were compared.The incidence of adverse events and prognostic indicators such as time of ICU stay and mechanical ventilation time within 28 days between the groups A and B were compared.
Results
After treatment,there was no significant difference in HR,CI,CVP or MAP between the groups A and B(P>0.05).After treatment,the oxygenation index of group A was lower than that of group C,but higher than that of group B(P<0.05).The oxygenation index of group B was lower than that of group C with a significant difference(P<0.05).The total incidence of adverse events in group A was lower than that in group B with a significant difference (P<0.05).The ICU stay in group A and mechanical ventilation time within 28 days were both shorter compared with those in group B with statistical significance (P<0.05).
Conclusion
For patients with severe ARDS,prone position ventilation can improve the oxygenation,reduce adverse events,shorten mechanical ventilation time,speed up symptom relief,and enhance therapeutic efficacy.
2018 Vol. 25 (22): 51-53 [
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166
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57
Clinical effect of endoscopic administration combined with oral administration of Sulfasalazine Enteric-Coated Tablets in the treatment of ulcerative colitis
LI Guo-bin;HUANG Rong-wang;WEI Di;CHEN Ming
Objective
To analyze the clinical effect of endoscopy combined with Sulfasalazine Enteric-Coated Tablets in the treatment of ulcerative colitis.
Methods
A total of 100 cases of ulcerative colitis in our hospital from October 2015 to October 2017 were selected and divided into the control group and the test group by random number table method,50 cases in each group.The control group were treated with Sulfasalazine Enteric-Coated Tablets only.The test group was treated with endoscopy combined with oral Sulfasalazine Enteric-Coated Tablets,and the overall clinical efficacy,albumin and hemoglobin index improvement and adverse reactions were observed.
Results
The recurrence rate of the test group after endoscopic treatment and reexamination was lower than that of the control group,and there was a statistical difference between the groups.The effective rate of the patients in the test group was higher than that of the control group(P<0.05);the incidence of adverse reactions in the test group was lower than that of the control group(P<0.05);the levels of albumin and hemoglobin of the test group were higher than those of the control group,the differences were statistically significant(P<0.05).
Conclusion
The treatment of ulcerative colitis by endoscopy combined with Sulfasalazine Enteric-coated Tablets is clinically significant.The main symptoms of the patients are obviously improved and there is no obvious recurrence.It is worthy of clinical promotion.
2018 Vol. 25 (22): 57-59 [
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202
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Comparison of the efficacy of one-time and multiple root canals in the treatment of chronic periapical periodontitis
XU Hai-hong;FENG Lian
Objective
To investigate the clinical effect of one-time canal therapy and multiple root canal therapy in patients with chronic periapical periodontitis.
Methods
A total of 98 cases of chronic periapical periodontitis were selected from February 2016 to February 2017.According the random digital table method,they were divided into experimental group and reference group,49 cases in each group.The patients in the control group were treated with multiple root canal therapy,while the patients in the experimental group were treated with one-time root canal therapy.The incidence of 7 d pain and the effect of periapical periodontal treatment in the two groups were compared.
Results
On the 7 day after operation,there was no grade 3 pain in the two groups.The total incidence of postoperative pain in the experimental group and the control group was 16.3%and 18.4%,respectively.There was no significant difference in the incidence of pain between the two groups(P>0.05).One year after operation,40 cases were cured and 7 cases were effective in the experimental group,the total effective rate was 95.9%in the control group;40 cases were cured and 7 cases were effective in the reference group,and the total effective rate was 93.9%.There was no significant difference in the total effective rate between the two groups (P>0.05).
Conclusion
The clinical effect and postoperative pain in patients with chronic apical periapical periodontitis are similar to that of multiple root canal therapy,but one-time root therapy can reduce the number of visits and shorten the time of treatment.It is worth popularizing in clinic.
2018 Vol. 25 (22): 60-62 [
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172
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63
Evaluation of efficacy and safety of tube-padding combined therapy in the treatment of high complex anal fistula
HUO Chao;PENG Wen;CHEN Xi-jing
Objective
To evaluate the efficacy and safety of the tube-padding combined therapy in the treatment of high complex anal fistula.
Methods
A total of 80 patients with high complex anal fistula in our hospital from October 2016 to September 2017 were selected and they were randomly divided into control group(n=40)and observation group(n=40).The control group was treated by incision-thread-drawing procedure,and the observation group was treated with the combined therapy of tubing and cotton.Clinical cure rate,pain level,wound healing time and anorectal pressure were compared,meanwhile recurrence rate and adverse reaction were observed.
Results
①There was no significant difference of the clinical cure rate and recurrence rate between the two groups(P>0.05);②The pain value of the observation group was significantly lower than that of the control group on the 10 th and 14 th day after treatment(P<0.05);③The wound healing time in the observation group was significantly shorter than that of the control group (P<0.01);④The 20 mm systolic pressure and resting pressure of the two groups were significantly lower than before operation at 3 months after healing(P<0.01),the systolic and resting pressure of 20 mm in the observation group were significantly higher than those of the control group at 3 months after healing,the differences were statistically significant(P<0.05).⑤There were no adverse reactions in both groups during the course of treatment.
Conclusion
The combined therapy of tubing and cotton with towed thread can be effective and safe in the treatment of high complex anal fistula.
2018 Vol. 25 (22): 63-65 [
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159
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66
Relationship between changes of high sensitivity C-reactive protein,brain natriuretic peptide and heart function in the patients with heart failure
YIN Qi-yun ZHANG Jian-xia LIU Gui-rong
Objective
To compare and analyze the results of high sensitivity C-reactive protein and brain natriuretic peptide in the treatment of patients with heart failure,and to study its relationship with heart function.
Methods
A total of 90 patients with chronic heart failure from January 2014 to January 2017 in our hospital were selected as the heart failure group,and their cardiac function was classified according to NYHA standards in international standards.The group name was secondary group,tertiary group,and quaternary group.There were 30 patients in each group.Another 30 healthy people were selected during the same period as the study group,and they were assigned to the regular group after their vital signs were determined to be normal.The levels of brain natriuretic peptide,high-sensitivity C-reactive protein,left ventricular ejection fraction,and the level of internal diameter at the end of diastolic degree were compared between the two groups.The changes of each indicator before and after the treatment were compared in the patients.The above data were compared with the data 6 months after receiving the treatment,and the changes were observed.In addition,the occurrence of cardiovascular and cerebrovascular events in the patients was understood through follow-up visits.The four indicators of BNP,hs-CRP,LVEF,and LVDD in the patients who had an incident and those who did not have an incident were compared.
Results
Before treatment,hs-CRP([12±2]mg/L),BNP([483±16]ng/L),and LVDD([58±2]mm)in the heart failure group were higher than those in the conventional group([3±1]mg/L,[33±13]ng/L,[42±2]mm),and LVEF([31±3]%)was lower than those inthe conventional group([43±4]%).The differences were statistically significant(P<0.05).Patients in the heart failure group had higher levels of hs-CRP([10±1]mg/L),BNP([129±21]ng/L),and LVDD([46±2]mm)than those in the conventional group after treatment,and LVEF([43±4]%)was lower than that in the conventional group.However,the levels of hs-CRP([10±1]mg/L),BNP([129±21]ng/L),and LVDD([46±2]mm)after treatment in the heart failure group were lower than those before treatment,and LVEF ([43±4]%)was higher than that before treatment.The differences were statistically significant(P<0.05).Patients in the tertiary group had BNP of(427±41)ng/L,LVDD of(58±3)mm,and hs-CRP of(12±3)mg/L.In the quaternary group,BNP was(780±59)ng/L,LVDD was (64±3)mm,and hs-CRP was (780±59)mg/L.The above indicators in the tertiary group and quaternary group were higher than those in the secondary group.The above indicators in the quaternary group were higher than those in the tertiary group.The differences were statistically significant(P<0.05).Six months after discharge,20 cases of the patient experienced secondary deterioration,and 70 cases did not appear any events.The levels of BNP,hs-CRP and LVDD in the patients with cardiovascular deterioration were higher than those in patients without cardiovascular deterioration.However,the left ventricular function was lower than the group without heart failure,and LVEF was lower than the group without heart failure.The differences were statistically significant(P<0.05).Patients in the tertiary group had BNP of(427±41)ng/L,LVDD of(58±3)mm,and hs-CRP of(12±3)mg/L.In the quaternary group,BNP was(780±59)ng/L,LVDD was(64±3)mm,and hs-CRP was(780±59)mg/L.The above indicators in the tertiary group and quaternary group were higher than those in the secondary group.The above indicators in the quaternary group were higher than those in the tertiary group.The differences were statistically significant(P<0.05).Six months after discharge,20 cases of the patient experienced secondary deterioration,and 70 cases did not appear any events.The levels of BNP,hs-CRP and LVDD in the patients with cardiovascular deterioration were higher than those in patients without cardiovascular deterioration.However,the left ventricular function was lower than the group without heart failure,and LVEF was lower than the group without heart failure.The differences were statistically significant(P<0.05).
Conclusion
The changes of high-sensitivity C-reactive protein and brain natriuretic peptide in heart failure can be used as a reliable indicator for the diagnosis of chronic heart failure.It also can provide an effective reference for checking the effective classification of disease levels after diagnosis.
2018 Vol. 25 (22): 66-69 [
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Application effect of Amiodarone in patients with rapid arrhythmia in emergency coronary heart disease
ZHU Ming-zhen;ZHU Ling-hua;DONG Yu-mei;HU Wen-chuan
Objective
To explore the application effect of Amiodarone in patients with rapid arrhythmia in emergency coronary heart disease(CHD).
Methods
A total of 100 CHD patients with tachyarrhythmia who were treated in our hospital from January 2016 to October 2017 were selected as the study subjects.By random section,conventional therapy was used in control group,and Amiodarone was adopted in experimental group.The efficacy,adverse reactions,blood pressure,heart rate levels,and electrocardiograph (ECG)monitoring results were compared between the two groups.
Results
The total effectiveness rate in the experimental group(96.00%)was significantly higher than that of the control group(74.00%),the difference was statistically significant(P<0.05).The incidence of adverse reactions in the experimental group was lower than that of the control group (P<0.05).In the experimental group,after therapy,the levels of blood pressure and heart rate were superior to those in the control group (P<0.05).In the experimental group,the test results during Q-T interval and P-R interval by ECG were higher than those of the control group,the differences were statistically significant(P<0.05).
Conclusion
Patients with tachyarrhythmia in CHD undergoing amiodarone treatment are safe and effective,which has positive significance for improving their prognosis.
2018 Vol. 25 (22): 70-72 [
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157
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73
Comparison of the effect of 24-hour ambulatory blood pressure monitoring and home blood pressure self-test in diagnosis and treatment of primary hypertension
MA Song-quan
Objective
To explore the application effect of 24 h dynamic blood pressure monitoring and home blood pressure self-measurement in the diagnosis and treatment of primary hypertension.
Methods
From January 2016 to March 2017,240 cases of patients with essential hypertension(EH)of cardiovascular internal medicine were adopted as the research object,and divided into normal group(120 cases)and the experimental group(120 cases)according to the envelope randomized method.The normal group routines used 24 h arterial blood pressure monitoring,and the experimental group routines used home blood pressure self-test training on basis the normal group.The blood pressure and blood pressure variability were compared between the two groups.
Results
After intervention,the experimental group′s blood pressure level was lower than before,the difference was statistically significant(P<0.05).After the intervention,the blood pressure level of the experimental group was lower than the normal group,the difference was statistically significant(P<0.05).The experimental group′s 24 h SBP after the intervention was (128.52±7.45)mmHg,lower than(137.56±7.96)mmHg in the conventional group after the intervention,the difference was statistically significant(P<0.05).There was no statistically significant difference in 24 h DBP after intervention between the two groups(P>0.05).
Conclusion
For the patients with primary hypertension,to adopt 24 h ambulatory blood pressure monitoring+home blood pressure self-test training is easy to monitor blood pressure at home,effective to control blood pressure and to improve blood pressure variability.Which is worthy adopting.
2018 Vol. 25 (22): 73-75 [
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195
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76
Effect of coronary stent in the treatment of acute myocardial infarction
KANG Feng-guang;XIAO Nan-hai
Objective
To explore the clinical effect of coronary stent in the treatment of acute myocardial infarction.
Methods
From June 2015 to December 2017,60 cases of patients with acute myocardial infarction treated in our hospital were selected as the research object,and divided into two groups by the principle of double blind,30 cases in each group.The control group accepted routine drug thrombolysis treatment,the analysis group treated for a heart coronary artery stents.The clinical effects of the two groups were compared,and the postoperative recovery effect of the analysis group were observed.
Results
There was no statistically significant difference between the two groups in heart rate and blood pressure level before treatment(P>0.05).After treatment,there was no statistically significant difference between the two groups in heart rate (P>0.05).The systolic blood pressure and diastolic blood pressure in analysis group was obviously lower than those in the control group,the difference was statistically significant(P<0.05).After treatment,the total excellent rate of coronary angiography (TIMI)blood flow grading in the analysis group was higher than that in the control group,the difference was statistically significant(P<0.05).
Conclusion
Heart coronary artery stents in patients with acute myocardial infarction(MI)has good effect,can reduce heart rate and blood pressure levels,improve patients restore normal blood flow to the heart heart function,which has clinical application and dissemination value.
2018 Vol. 25 (22): 76-78转81 [
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196
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79
Effect of intracoronary injection of verapamil through restructured balloon catheter in the treatment of acute coronary syndrome
WEN Yong-jun;LUO Hong-chun
Objective
To investigate the effect of intracoronary injection of verapamil through restructured balloon catheter in the treatment of acute coronary syndrome (ACS).
Methods
A total of 90 ACS patients with no-reflow and slow flow who underwent percutaneous coronary intervention in our hospital from December 2015 to July 2017 were selected as the subjects.They were divided into control group and observation group by random number table method,with 45 cases in each group.In the control group,verapamil was injected into the coronary artery with a simple guiding catheter,and in the observation group,verapamil was injected through restructured balloon catheter.The grading of thrombolysis in myocardial infarction (TIMI)and changes of corrected TIMI frames were compared between the two groups,and the incidence of adverse cardiovascular events during hospital stay was also observed.
Results
The TIMI flow grading of the observation group was better than that of the control group.The number of corrected TIMI frames was less than that of the control group.The incidence of adverse cardiovascular events in the observation group(6.67%)was lower than that in the control group(31.11%),the difference was statistically significant(P<0.05).
Conclusion
Treatment of acute coronary syndrome characterized by no-reflow and slow flow with intracoronary injection of verapamil through restructured balloon catheter obtains a remarkable effect on improving coronary blood flow,reducing the occurrence of adverse cardiovascular events,and guaranteeing the own health status,which is worthy of clinical promotion.
2018 Vol. 25 (22): 79-81 [
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180
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82
Clinical effect of decompression of large bone flap and roofing of temporal muscle treating large area cerebral infarction
ZHOU Xi-han;HUANG Rui-hong;HUANG Chen-ming
Objective
To explore the effect of decompression of large bone flap and roofing of temporal muscle treating large area cerebral infarction.
Methods
A total of 70 cases with large area cerebral infarction treated in our hospital from March 2011 to March 2017 were selected as the research subjects,and they were randomly divided into the conservative group(35 cases)and the operation group(35 cases).The conservative group was treated with conventional medical treatment,while the operation group was treated with arge bone flap and roofing of temporal muscle therapy.The volume change of cerebral infarction focus,the total incidence of complications,mortality and long-term efficacy were compared between the two groups.
Results
The volume of cerebral infarction focus in the operation group after 1,2 and 4 weeks treatment was smaller than that of the conservative group,and the differences were statistically significant(P<0.05).The total incidence of complication and mortality rate in the operation group were lower than those in the conservative group(P<0.05).After half a year of follow-up,the good rate of functional recovery in the operation group was higher than that of the conservative group,and the bad rate of functional recovery was lower than that of the conservative group,and the differences were statistically significant(P<0.05).
Conclusion
Clinical effect of large bone flap and roofing of temporal muscle treating large area cerebral infarction is better than conventional medical treatment.
2018 Vol. 25 (22): 82-84转87 [
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157
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85
Effect of standard large bone flap craniotomy in the treatment of severe craniocerebral injury
WANG Ke;WANG Ting
Objective
To explore the effect of standard large bone flap craniotomy in the treatment of severe craniocerebral injury.
Methods
A total of 64 cases with severe craniocerebral injury treated in our hospital from December 2015 to November 2017 were selected and randomly divided into the observation group(n=32)and the control group(n=32).The control group was treated with routine bone flap craniotomy treatment,while the observation group was treated with standard large bone flap craniotomy.The operative effect and nerve function defect score between the two groups were observed.
Results
After treatment,the good recovery rate of the observation group was obviously higher than that of the control group,the fatality rate of the observation group was obviously lower than that of the control group (P<0.05).The nerve function defect score after 1 month operation in the observation group was significantly lower than that in the control group(P<0.05).
Conclusion
The standard large bone flap craniotomy in the treatment of severe head injury has obvious effect,which can effectively improve neurologic deficits,and its clinical use value is high.
2018 Vol. 25 (22): 85-87 [
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155
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88
Effect of ureteroscopic holmium laser lithotripsy in the treatment of middle and lower ureteral calculi
DU Hong-bing;LIU Wen-hong;YANG Feng-sheng;GUO Xiang-yan;HUANG Ji-mao
Objective
To explore the clinical effect of ureteroscopic holmium laser lithotripsy and laparoscopic ureterolithotomy in the treatment of ureteral calculi.
Methods
A total of 110 patients with middle and lower ureteral calculi treated from January 2013 to January 2017 were randomly divided into the control group (n=54)and the observation group (n=56).The ureteroscopic pneumatic lithotripsy and the ureteroscopic holmium laser lithotripsy were performed respectively.The clearance effect,perioperative indicators and safety of two groups were compared.
Results
The stone clearance rate in the observation group was 89.3%,the control group was 94.4%,the difference was not statistically significant(P>0.05).In 1 years after operation,the recurrence rate of stones in observation group was 5.4%,while in control group,stone recurrence rate was 1.9%,there was no significant difference between two groups(P>0.05).The operation time,the time of hospitalization and the recovery time of gastrointestinal function in the observation group were significantly shorter than those in the control group,the amount of bleeding in the operation was significantly less than that in the control group,and the postoperative analgesic drug use rate was significantly lower than that in the control group,the difference was statistically significant(P<0.05).There was no significant difference in the incidence of complications between the two groups(P>0.05).
Conclusion
The effect of ureteroscopic holmium laser lithotripsy in the treatment of middle and lower ureteral calculi is better than that of ureteroscopic pneumatic lithotripsy.The postoperative injury is small,the recovery is fast.It is worthy of clinical application.
2018 Vol. 25 (22): 88-90 [
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136
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91
Comparison observation of total hip arthroplasty by SuperPATH approach and posterolateral approach
WU Hua-gui
Objective
To investigate the comparison effect of total hip arthroplasty by SuperPATH approach and posterolateral approach.
Methods
The clinical data of 100 patients undergoing total hip arthroplasty treated in our hospital from December 2014 to December 2017 were analyzed.They were divided into the posterolateral approach group (n=50)and the SuperPATH approach group(n=50)according to different approach methods.The operation time,intraoperative blood loss,length of incision,postoperative functional exercise time and timed up and go test(TUG)at different time points after operation were compared between two groups.
Results
The operation time of the patients in the Super-PATH approach group was higher than that in the posterolateral approach group,the intraoperative blood loss was less than that in the posterolateral approach group,and the length of the incision and the postoperative functional exercise time were lower than those in the posterior lateral approach group,with statistically significant difference(P<0.05).The TUG of patients in two groups after operation at 5,14,30,60 d were significantly shorter than that before operation,and the differences were statistically significant(P<0.05).The TUG of patients in the SuperPATH approach group after operation at 5,14,30,60 d were significantly shorter than those in the posterolateral app roach group,and the differences were statistically significant(P<0.05).
Conclusion
Total hip arthroplasty by Super PATH approach has the advantages of minimal invasion and rapid recovery,which is worthy of clinical promotion and application.
2018 Vol. 25 (22): 91-93 [
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165
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94
Clinical analysis of spinal discoscopic surgery in the treatment of lumbar disc herniation
XING You-jun;TAN Lei
Objective
To analyze the clinical effect of spinal discoscopic surgery in the treatment of lumbar disc herniation.
Methods
Eighty-two patients with lumbar disc herniation treated in our hospital from June 2016 to August 2017 were selected as study subjects.They were divided into control group (n=41)and observation group (n=41)according to the computerized random coding method.Small incision surgery was used in the control group,and the observation group was treated with spine discoscopic surgery.The surgical indexes and evaluation results of the two groups of patients were compared.
Results
The intraoperative blood loss in the observation group was(20.25±6.34)ml,which was lower than that in the control group([65.59±10.34]ml),and the difference was statistically significant(P<0.05).The operation time of the observation group was(59.68±3.32)min,the incision length was(1.21±0.28)cm,the number of hospital stays was(4.26±2.01)d,which were respectively shorter than those of the control group([75.54±8.15]min,[5.69±1.35]cm,[8.56±2.29]d),and the differences were statistically significant(P<0.05).There were no significant differences in straight leg elevation,oswestry disability index(ODI),and visual analogue scale(VAS)score before the operation in both groups(P>0.05).The angle of straight leg elevation of two groups after operation was higher than that before operation,the dysfunction index and pain scores after operation were lower than those before operation,and the differences were statistically significant(P<0.01).The angle of straight leg elevation in the observation group after operation was higher than that in the control group,the dysfunction index and pain scores were lower than those in the control group,and the differences were statistically significant(P<0.05).
Conclusion
Spinal discoscopic surgery in the treatment of lumbar disc herniation has the advantages of less bleeding,shorter operative time,and can gradually restore the patient′s normal mobility.
2018 Vol. 25 (22): 94-96 [
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154
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97
Analysis of the effectiveness and clinical prognosis of pelvic external fixation in the treatment of pelvic fractures
ZENG Suo-lin
Objective
To explore the clinical efficacy of pelvic external fixation in the treatment of pelvic fractures.
Methods
From May 20
th
,2016 to May 20
th
,2017,a total of 106 patients with pelvic fractures treated in our hospital were selected as research objects and they were divided into the conventional group(n=53)and the experimental group(n=53)by the envelop random grouping method.In the conventional group,patients were treated with a traditional incision reduction for internal fixation,while in the experimental group,external pelvic fixation was added.The excellent and good therapeutic rate,the time of porosis,and the time of getting out of bed were compared between the two groups.
Results
The rate of excellent and good treatment in the experimental group (98.11%)was significantly higher than that of the conventional group(79.24%),and the difference was statistically significant(P<0.05).The time of porosis and the time of getting out of bed were significantly shorter in the experimental group([30.85±4.12]d,[3.36±0.50]weeks)than in the conventional group([37.85±4.25]d,[4.18±0.46]weeks),with statistical significance(P<0.05).
Conclusion
For patients with pelvic fracture,external pelvic fixation can obtain a remarkable effect,which shortens the time for getting out of bed and promotes early recovery of the body.
2018 Vol. 25 (22): 97-99 [
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181
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100
Effect comparison of percutaneous transforaminal endoscopic discectomy and fenestration discectomy in the treatment of lumbar intervertebral disc herniation
LIAO Qiang
Objective
To compare the clinical effect of percutaneous transforaminal endoscopic discectomy and fenestration discectomy in the treatment of lumbar intervertebral disc herniation.
Methods
A total of 94 cases of patients with lumbar intervertebral disc herniation treated in our hospital from August 2016 to December 2017 were selected as research objects and divided into the control group(n=44)and the study group(n=50)according to the method of touching the ball.The control group was treated with fenestration discectomy while the study group was treated with percutaneous transforaminal endoscopic discectomy.The results of indexes of curative effect,visual analogue scale (VAS)of pain,Japanese Orthopaedic Association (JOA)lumbar function score,intraoperative blood loss,and the average hospitalization time were compared and analyzed between the two groups.
Results
The excellent and good rate of patients in the study group was 98.00%,which was higher than that in the control group(86.36%),and the difference was statistically significant(χ
2
=4.598,P<0.05).The VAS scores of patients after treatment of two groups were lower than those before treatment,the JOA scores were higher than those before treatment,and the differences were statistically significant(P<0.05).The VAS score of after treatment in the study group was lower than that of the control group,the JOA was higher than that of the control group,and the differences were statistically significant(P<0.05).The intraoperative blood loss in the study group was less than that in the control group,the time of average hospitalization in the study group was shorter than that in the control group,and the differences were statistically significant(P<0.05).
Conclusion
Compared with fenestration discectomy,percutaneous transforaminal endoscopic discectomy in the treatment of lumbar disc herniation is effective,which is worthy of clinical application.
2018 Vol. 25 (22): 100-102转106 [
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148
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103
Effect comparison of surgical treatment and manual reduction plaster external fixation in the treatment of distal radius fracture
MA Jia;MENG Qing-feng;ZHENG Lian-xiang;XU Ying-hui
Objective
To investigate effect of surgical treatment and manual reduction plaster external fixation in the treatment of distal radius fracture.
Methods
A total of 150 patients with distal radius fracture treated in our hospital from November 2013 to November 2017 were selected as research objects.They were divided into control group(n=75)and observation group(n=75)according to the random number table method.The control group was treated with manual reduction plaster external fixation while the observation group was given surgical treatment.The imaging examination and functional evaluation were performed before and after treatment,and the surgical effect and complications of two groups were compared.
Results
Ulnar angle,palmar angle and radius height after treatment of two groups were higher than those before treatment,the ulnar displacement was lower than that before treatment,and the differences were statistically significant(P<0.05).Ulnar angle,palmar angle and radius height after treatment in the observation group were higher than those in the control group,the ulnar displacement was lower than that in the control group,and the differences were statistically significant(P<0.05).The score of wrist joint function after treatment of two groups were higher than that before treatment,the score of pain of two groups were lower than that before treatment,and the differences were statistically significant(P<0.05).The score of wrist joint function after treatment in the observation group was higher than that in the control group,the score of pain was lower than that in the control group,and the differences were statistically significant(P<0.05).The excellent rate after treatment in observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).The total incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).
Conclusion
Compared with manual reduction plaster external fixation,surgical treatment has better effect in the treatment of distal radius fracture and can improve joint function,which has high safety and is worthy of clinical application.
2018 Vol. 25 (22): 103-106 [
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162
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107
Effects of biofeedback electrical stimulation and pelvic floor muscle exercise at different periods on postpartum pelvic floor function recovery
LI Hua-wei;LI Gui-mei;HUANG Xiao-yu
Objective
To study effect of biofeedback electrical stimulation combined pelvic floor muscle exercise at different periods on pelvic floor function recovery of postpartum women.
Methods
A total of 600 cases of full-term parturient women receiving treatment in our hospital from December 2016 to December 2017 were selected.According to the time of treatment,it was divided into three groups:A,B and C group.Biological feedback electrical stimulation and pelvic floor muscle training were initiated at 6 weeks after delivery,10 weeks after delivery and 12 weeks after delivery,respectively.The incidence of urinary incontinence,vaginal muscle tension and pelvic floor muscle strength were compared in three groups.
Results
There was no statistically significant difference in pelvic floor muscle tension between three groups before treatment(P>0.05).After treatment,group A and group B maternal pelvic floor muscle tension were recovered,and maternal effect of pelvic floor muscle tone recovery of group A was better than that of group B puerperal,difference were statistically significant(P<0.05).There was no significant change in pelvic floor muscle tension in group C (P>0.05).Before treatment,there was no significant difference between incidence of urinary incontinence and vaginal muscle voltage in three groups(P<0.05).After treatment,the rate of group A and group B maternal urinary incontinence decreased obviously,vaginal muscles voltage obviously improved,and maternal urinary incontinence rate of group A was lower than that in group B,vaginal muscles voltage was significantly higher than group B,the difference was statistically significant(P<0.05),maternal rate of urinary incontinence and vaginal muscle group C voltage had no obvious change,there was no statistically significant difference(P>0.05).
Conclusion
Timely receiving biofeedback electrical stimulation and maternal pelvic floor muscle exercise can significantly increase the pelvic floor muscle,reduce occurrence of urinary incontinence,and effectively enhance recovery of maternal vaginal muscles voltage.
2018 Vol. 25 (22): 107-109 [
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150
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110
Analysis efficacy of oral contraceptives and intrauterine devices after induced abortion
PAN Zhuo;SU Jing-jing
Objective
To explore the clinical efficacy of taking oral contraceptives and placing intrauterine devices(IUD)after abortion.
Methods
A total of 120 cases with aborted were randomly selected from January 2015 to November 2017 in Panjin People′s Hospital and were divided into three groups according to random number table method,40 cases in each group.Postoperative patients with Marvelon,antibiotics and Yimucao Capsules were treated to oral contraceptive group;Patients were treated with TCU380A combined antibiotics and Yimucao Capsules in IUD group;And antibiotics and Yimucao Capsules were taken in control group.The efficacy of the three groups were compared.
Results
Compared to both IUD group and control group,vaginal bleeding time,endometrial repair time and menstrual recovery time in oral contraceptive group were shorter(P<0.05).There was no statistical difference IUD group and control group(P>0.05).Oral contraceptive group and IUD group were better than control group in the aspect of preventing intrauterine adhesions and contraception situation,with a statistical difference(P<0.05).None of the three groups were infected.
Conclusion
Taking oral contraceptives instantly after induced abortion can improve endometrium repairmen,shorten vaginal bleeding time and menstrual recovery time,reduce intrauterine adhesions rate and recurrent abortion rate.Intrauterine placed IUD after induced abortion can reduce the rate of intrauterine adhesions,and improve contraceptive effect.
2018 Vol. 25 (22): 110-112 [
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141
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113
Epidemiological characteristics and clinical analysis of brucellosis in 46 children
HU Dan;ZHAO Ye;LIN Jing
Objective
To investigate the epidemiological characteristics and clinical analysis of 46 children with brucellosis.
Methods
A total of 46 children patients with brucellosis who were diagnosed in our hospital from October 2012 to October 2015 were selected.The epidemiological data,clinical manifestations and auxiliary examination characteristics of children patients were summarized.The complicationsm epidemiologym morbiditym and treatment of all children patients were analyzed.
Results
The incidence rate of complications was the highest in bronchitis with a total of 26.0%.Among them,the incidence rate of upper respiratory tract infection,left hip arthritis,liver damage,acute myositis and Klebsiella pneumoniae was 2.2%.Fever accounted for the largest proportion,with a total of 22 cases,and a total of 47.8%;hyperhidrosis was in 6 cases,accounting for 13.0%.Fatigue and chills were in 5 cases,accounting for 10.8%.There were 4 cases of joint pain and hepatomegaly,and the incidence rate was 8.7%.In the results of treatment,the healing rate accounted for 69.6%,the significant effect was 26.1%,the effective rate was 4.3%,and the invalidity rate was 0.0%.
Conclusion
The clinical manifestations of brucellosis are diverse.diagnosis of blood cultures in the patients with unexplained fever for a long period of time and early treatment can control the early development of the disease and improve clinical treatment effect.
2018 Vol. 25 (22): 113-115 [
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153
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116
Application effect of different surgical procedures in the treatment of cesarean scar pregnancy patients
PAN Rui-qin
Objective
To analyze the impact of different surgical procedures in the life quality for cesarean scar pregnancy patients.
Methods
A total of 134 cesarean scar pregnancy patients treated from June 2014 to May 2017 in our hospital were selected.The subjects were assigned to two groups according to random number table method,67 cases in each group.Group A was took the transvaginal resection plus uterus neoplasty;group B was took the bilateral uterine artery embolization plus complete curettage of uterine cavity.The clinical effect and life quality were probed.
Results
There were no significant between-group difference in the intraoperative blood loss and recovery time of human chorionic gonadotropin(β-HCG)(P>0.05);the operation time in the group A was significantly longer than that in the group B(P<0.05);there was no significant between-group difference in the total effective rate(92.54%vs.95.52%)(P>0.05);after 3 month of surgery,there were no significant between-group difference in the mental state and environment scores(P>0.05);the scores of social relations and physiological function in the group B were higher than that in the group A,with a statistical difference (P<0.05);after 6 month of surgery,there were no significant between-group difference in the scores of social relations,physiological function,mental state and environment(P>0.05).
Conclusion
Both of the therapies have the fair effect in cesarean scar pregnancy.However,the bilateral uterine artery embolization plus complete curettage of uterine cavity can better improve the short-term life quality,stabilize the illness state and improve the clinical prognosis.
2018 Vol. 25 (22): 116-118 [
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147
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119
Influence of Doula accompanied by joint delivery analgesia on quality of delivery
DENG Cai-xia;CHEN Hui;ZHOU Xiao-ying;LI Shen-shen;LIANG Mei-juan;MAI Ling-juan;ZHANG Jun-hong
Objective
To analyze the influence of Doula accompanying joint delivery analgesia on quality of delivery.
Methods
A total of 132 cases of vaginal delivery women admitted to the obstetrics and gynecology department of our hospital from September 2017 to February 2018 were selected,according to the random envelope method and consent,they were divided into control group(n=66)and study group(n=66).The control group was used a simple guide to accompany the childbirth.The study group was guided by a combination of Doula and delivery analgesia.The pain levels,emergency cesarean section rate,postpartum hemorrhage rate,labor time,neonatal asphyxia rate,and postpartum adverse events were analyzed.
Results
The severe pain rate,emergency cesarean section rate,postpartum hemorrhage rate,labor time,neonatal asphyxia rate and incidence of postpartum adverse events were lower in the study group than in the control group(P<0.05).
Conclusion
In the process of maternal childbirth,giving Doula accompanying anesthesia with analgesic delivery can relieve the pain and shorten the duration of labor.It can also reduce the rate of emergency caesarean section,postpartum hemorrhage,neonatal asphyxia,and has high clinical application value.It is worth promoting.
2018 Vol. 25 (22): 119-121 [
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149
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122
Correlation analysis on C-reactive protein,interleukin-17,pigment epithelium-derived factor and immunoglobulin E in children patients with asthma
XU Bo-hua
Objective
To analyze the expression of C-reactive protein(CRP),interleukin-17(IL-17)and pigment epithelium derived factor(PEDF)in acute attack of children patients with asthma and the correlation between the three indices and immunoglobulin E (IgE).
Methods
A total of 110 children patients with acute attack of asthma who were diagnosed in our hospital from January 2016 to December 2017 were randomly selected.According to the conditions of the children patients,they were divided into group A(mild asthma,53 cases)and group B(moderate and severe asthma,57 cases).At the same time,a total of 50 healthy children during the same period of time from the Health Examination Center were selected as healthy groups.The serum levels of CRP,IL-17,PEDF,and IgE in the three groups of children were compared.The correlations between serum CRP,IL-17,PEDF and IgE in the children patients with acute attack of asthma were analyzed.
Results
The serum levels of CRP,IL-17,IgE and PEDF in group B were significantly higher than those in the healthy group and group A,and the differences were statistically significant(P<0.05).The serum levels of CRP,IL-17,IgE and PEDF in group A were significantly higher than those in the healthy group,and the differences were statistically significant(P<0.05);the serum IL-17 level in the asthmatic children was positively correlated with IgE(r=0.679,P<0.05);there was no significant correlation between serum PEDF and CRP and IgE in asthmatic children (r=0.186,0.205,P>0.05).
Conclusion
CRP,IL-17,and PEDF are involved in the inflammatory response during acute attack of asthma in children.Interleukin-17 level is closely correlated to the expression of immunoglobulin E.
2018 Vol. 25 (22): 122-124 [
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155
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125
Analysis of risk factors for shoulder dystocia
LIU Xia-yun;Lin Yan-na
Objective
To analyze the risk factors of shoulder dystocia and provide reference for clinical prevention of shoulder dystocia.
Methods
A total of 22 665 cases of full-term pregnancy,single fetus,head position and vaginal delivery in the department of obstetrics and gynecology in our hospital from January 2009 to January 2018 were collected,of which 55 cases of shoulder dystocia(shoulder dystocia group)were found.Then,the study randomly selected 110 patients(control groups)from the remaining patients who did not have shoulder dystocia and collected clinical data of all patients.Clinical data were collected and Logistic regression analysis was used to analyze risk factors for shoulder dystocia.
Results
Form January 2009 and January 2018,the rate of shoulder dystocia in our hospital was 0.24%.Then univariate analysis showed that the factors such as uterine height,abdominal circumference,first stage of labor,second stage of labor,combined with diabetes(including gestational diabetes mellitus),birth weight,length and chest circumference were the influencing factors of shoulder dystocia (P<0.05).Gestational age,head circumference did not affect the shoulder dystocia(P>0.05).Further use of Logistic regression test showed that diabetes mellitus(including gestational diabetes mellitus),second stage of labor,abdominal circumference,body weight,uterine height,first stage of labor,body length and chest circumference were risk factors for shoulder dystocia and their risk decreased in turn (P<0.05).
Conclusion
Due to the multiple factors of maternal and fetal factors,shoulder dystocia is recommended to correctly predict and manage the occurrence of shoulder dystocia according to the actual situation and high risk factors of shoulder dystocia.
2018 Vol. 25 (22): 125-127 [
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145
)
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128
Comparison of prophylactic cervical cerclage and expectant therapy for cervical incompetence
HUANG Qiu-ming;WU Yuan-yuan
Objective
To observe the therapeutic effects of prophylactic cervical cerclage and expectant therapy in cervical insufficiency (CIC).
Methods
A total of 120 CIC hospitalized patients admitted to our department of obstetrics from January 2016 to December 2017 were selected as the study subjects.They were divided into control group(60 cases)and observation group(60 cases)according to random number table method.The control group was used expectation treatment,observation group was performed preventive cervical cerclage treatment,the pregnancy outcomes of the two groups of patients were compared.
Results
The patients in the observation group had significantly higher rate of term and neonatal survival than the control group,the differences were statistically significant(P<0.05).The abortion rate and premature delivery rate in the observation group were significantly lower than those in the control group,the differences were statistically significant(P<0.05).There was no significant difference in prolonged pregnancy between the two groups(P>0.05).The patients in the observation group who underwent surgery from 12 to 17 weeks of gestation were significantly higher than those in the 18 to 23 weeks group,and the preterm birth rate was lower than that of 18 to 23 weeks,the difference was statistically significant(P<0.05).
Conclusion
Early implementation of prophylactic cervical cerclage contrast to expect full-term therapy can improve the yield and neonatal survival in patients with CIC,reduce the abortion rate and the rate of preterm birth,which is worthy of reference promotion.
2018 Vol. 25 (22): 128-130 [
Abstract
] (
138
)
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131
Clinical effect analysis of Budesonide combined with Montelukast in children with asthma
WANG Xiao-qing
Objective
To investigate the effect of Budesonide combined with Montelukast on pulmonary function,immune function and growth of children with asthma.
Methods
A total of 80 children with bronchial asthma admitted in our hospital from January 2016 to April 2017 were selected and were divided into observation group and control group,according to ramdom number table method,40 cases in each group.The control group was received regular oral administration of Montelukast,sodium chewable tablets 5 mg/tablet,taking 5 mg every night before going to bed,the observation group were inhaled a small dose of Budesonide nasal spray on the basis of the control group,the two groups were used continuously for 1 year.Then the lung function,the level of IgM,IgG and IgA,the changes of CD4
+
,CD8
+
,and CD4
+
/CD8
+
after intervention and the height growth rate,weight gain and bone mineral content after intervention were compared.
Results
After intervention,FEV
1
in the observation group was higher than that in the control group(P<0.05),and FEV
1
/FVC level in the observation group was higher than that in the control group(P<0.05).After intervention,IgM,IgG and IgA levels in the observation group were significantly higher than that in the control group(P<0.05),After intervention,the levels of CD4
+
and CD8
+
in the observation group were higher than that in the control group(P<0.05),and the ratio of CD4
+
/CD8
+
was greater than that in the control group(P<0.05).The height growth rate in the observation group was slower than that in the control group (P<0.05).The body weight growth rate in the observation group was slower than that in the control group (P<0.05),the bone mineral content in the observation group was lower than that in the control group,the differences were statistically significant(P<0.05).
Conclusion
For children with asthma,inhaling a small dose of Budesonide for a long time can effectively improve the children′s lung function and body′s immune capacity,but it can have an impact on the body′s growth and development,so the clinical use should pay attention to the advantages and disadvantages.
2018 Vol. 25 (22): 131-133 [
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] (
151
)
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134
The role of biofeedback electrical stimulation in postpartum pelvic floor muscle function recovery
WANG Xiao-yan
Objective
To explore the effect of biofeedback electrical stimulation in postpartum pelvic floor muscle function recovery.
Methods
A total of 500 primiparae with pelvic floor dysfunction admitted in our hospital from January to December 2016 were selected and their clinical data were analyzed retrospectively.A total of 250 cases of pelvic floor rehabilitation training with vaginal dumbbell were used as control group.A total of 250 patients with vaginal dumbbell training and biofeedback electric stimulation were used as the observation group.The recovery effects of pelvic floor muscle were observed and compared between the two groups after 5 days and 3 months of treatment.
Results
The muscle voltage of the patients in the observation group was significantly higher than that in the control group at 3 months postpartum(P<0.05),and the muscle strength of the pelvic floor in the observation group was significantly higher than that in the control group at 3 months postpartum,the differences were statistically significant(P<0.05).The total effective rate of the observation group was significantly higher than that of the control group(P<0.05).
Conclusion
The treatment of postpartum pelvic floor dysfunction with biofeedback electric stimulation combined with vaginal dumbbell can obviously improve the pelvic floor organ function and prevent pelvic floor dysfunction effectively.It is worth popularizing.
2018 Vol. 25 (22): 134-136 [
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] (
146
)
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137
Application value of dynamic electrocardiogram and conventional electrocardiogram in diagnosis of children with arrhythmia
KANG Wei
Objective
To explore the application value of dynamic and conventional electrocardiogram(ECG)in the diagnosis of children with arrhythmia.
Methods
A total of 50 children with arrhythmia treated in our hospital from January 2016 to December 2017 were selected as the subjects.They were all performed with dynamic and conventional ECG respectively.The test results of dynamic and conventional ECG and heart rate variability in patients with ventricular arrhythmia and non-ventricular arrhythmia was observed and analyzed.
Results
Children with arrhythmia undergone dynamic ECG,the detection rates of conduction block,atrial premature contraction,ventricular premature contraction,ventricular tachycardia,and supraventricular tachycardia were significantly higher than those of conventional ECGs,the difference was statistically significant(P<0.05).In children with ventricular arrhythmia,the PNN50 in heart rate variability (the ratio of heart beat closing to normal RR interval difference over 50 ms to that in the normal sinus interval)was much higher than those in children with non-ventricular arrhythmia,among which root mean square difference of adjacent RR interval(rMMSD),mean standard deviation of RR interval during 5 min within 24 h(SDNNindex),and standard deviation of RR interval in all sinus beats(SDNN)were all lower than those children with non-ventricular arrhythmia,the differences were statistically significant(P<0.05).
Conclusion
Dynamic and conventional ECG both obtain certain values in the diagnosis of arrhythmia in children,but higher value is reflected in the former.
2018 Vol. 25 (22): 137-139 [
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] (
165
)
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140
Comparison of the application value of two contrast agent injection methods in hysterosalpingography
ZHANG Xian;BAO Jun-chu;FANG Wu
Objective
To analyze the difference in the value of two contrast agent injection methods in hysterosalpingography.
Methods
A total of 367 patients with infertility who were treated in our hospital from January 2015 to March 2017 were selected as the subjects,and divided into the control group(n=130)and observation group(n=247)according to the contrast injection method.In the control group,the physician manually injected the uterine tubal contrast agent at the bedside.The observation group used the remote technique to operate the microinjection pump to inject the uterine tubal contrast agent into the patient′s body.The image quality,diagnostic results,and pain status of the two groups were analyzed (VAS was used to assess the degree of pain).
Results
The image quality of the observation group(100.00%)was significantly higher than that of the control group(73.85%)(P<0.01).There was no significant difference in the results of the fallopian tube angiography between the two groups(P>0.05),but the difference of the uterine angiography between the two group was statistically significant(P<0.01).The total pain of the infusion imaging in the observation group was 59 cases(23.89%),which was significantly lower than the control group for 107 cases(82.31%)(P<0.01).VAS scores in the observation group ([1.71±0.35]points)was significantly lower than that in the control group([6.45±1.12]points),the difference was statistically significant(P<0.01).
Conclusion
The use of remote technology to operate the microinjection pump to inject the contrast agent into the patient′s body can effectively protect the quality of the contrast image,reduce the patient′s pain and improve the diagnostic accuracy.
2018 Vol. 25 (22): 140-142 [
Abstract
] (
131
)
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143
Clinical study of medicinal vesiculation therapy treating allergic rhinitis
CHEN Qin;LAN Jia
Objective
To explore the clinical effect of medicinal vesiculation therapy trerating allergic rhinitis.
Methods
A total of 104 patients with allergic rhinitis admitted into Yingtan People′s Hospital and Guixi Hospital of Traditional Chinese Medicine from January 2016 to September 2017 were selected and they were randomly divided into the two groups according to the sequence of hospitalization time,and there were 52 cases in each group.The control group was given conventional treatment(oral Loratadine Tablets,1 tablets each time,1 time/day),while the observation group was given medicinal vesiculation therapy on the basis of the control group (canicular days a year and the third nineday period after the winter solstice to give moxibustion acupoint sticking),3 years were 1 course of treatment.The treatment effect and the attack of the disease within 6 months after treatment between the two groups were compared.
Results
The total clinical effective rate(96.15%)in the observation group was significantly higher than that in the control group (80.76%),and the difference was statistically significant(P<0.05).Within 6 months after treatment,the attack rate(26.92%)in observation group was significantly lower than that in the control group(82.70%),and the difference was statistically significant(P<0.05).
Conclusion
The medicinal vesiculation therapy can obviously improve the clinical symptoms of allergic rhinitis,improve the total effective rate of treatment and reduce the number of recurrence.It is worthy of clinical application.
2018 Vol. 25 (22): 143-145 [
Abstract
] (
144
)
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146
Clinical effect of community Senna preparation treating acute nephritis
ZHONG Xi-wen;ZHONG Yuan-hui;ZOU Zeng-ye
Objective
To explore the clinical effect of community Senna preparation treating acute nephritis.
Methods
Sixty-eight children with acute nephritis admitted into our hospital from June 2015 to March 2017 were selected and they were divided into the Chinese medicine group and the western medicine group according to the random number table method,and there were 34 cases in each group,and the above-mentioned two groups was given Senna preparation and conventional western medicine.The clinical effect,various renal function indexes and adverse reactions were compared between the two groups.
Results
The total effective rate and total cure rate in the Chinese medicine group were significantly higher than those of the western medicine group,and the differences were significant(P<0.05).The renal function indexes such as serum creatinine,1 h urinary red blood cell excretion rate,24-hour urinary protein quantification,urea nitrogen,albumin,blood β
2
microglobulin in the Chinese medicine group were significantly lower than those of the western medicine group with significant differences(P<0.05).The total incidence of adverse reactions in the Chinese medicine group(5.88%)was significantly lower than that in the western medicine group(20.59%)(P<0.05).
Conclusion
Community Senna preparation treating acute nephritis can significantly improve the children′s renal function indicators,contribute to the improvement of clinical efficacy,and has a higher safety,and it should be widely promoted.
2018 Vol. 25 (22): 146-148 [
Abstract
] (
127
)
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149
Study on breast-cancer-related knowledge and health education need of rural women in Enping city
CHEN Wen-fang;LIN Qi-mou
Objective
To explore the knowledge about breast cancer and the demand for health education of rural women in Enping city.
Methods
The questionnaire survey was conducted on women in rural area of Enping city from February 2016 and April 2017 using questionnaire designed.After acquisition of the informed consent of the respondents,the general information,the awareness degree of related knowledge of breast cancer,the understanding of the breast self-examination methods and demand for health education were investigated for the female residents.
Results
The incidence of female breast disease in rural area of Enping city was 56.0%,and the women with the features of low cultural level,no breast self-examination,family history of disease,older people had a higher incidence of breast disease and poor understanding of breast-cancer-related knowledge.Meanwhile,women in rural area of Enping city had a higher demand for breast cancer prevention and breast health knowledge,and it accounted for 78.3%and 77.1%respectively.And most of the women hoped to receive health education through TV/radio,medical staff,brochures and lectures.
Conclusion
The awareness of breast-cancer-related knowledge in rural women is lower and the incidence of clinical breast cancer is higher,as the result of which the residents have higher demand for breast cancer prevention and breast health knowledge.
2018 Vol. 25 (22): 149-151 [
Abstract
] (
162
)
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152
Analysis of the results of syphilis screening for inpatients in our hospital in 2016~2017
JIN Xiu-ying
Objective
Two methods were used for syphilis diagnosis test,namely,specific treponema pallidum antibody test and non specific syphilis serological test,to screen syphilis for inpatients in different age groups of our hospital.
Methods
The syphilis serological examination results of inpatients in our hospital were retrospectively analyzed in 2016-2017.All syphilis positive patients were summarized and analyzed.
Results
The syphilis positive rate was 1.46%in 2016,and it was 1.60%in 2017.A total of 24 800 patients were examined,among them,there were 380 serological positive patients with syphilis,among them,there were 64 cases(16.800%)for 1-<50 years old,there were 109 cases(28.600%)for 50-70 years old,and there were 205 cases (53.940%)for>70 years old,and there were 2 cases(0.526%)for<1 year old,and there was a significant difference in the constituent ratio between >70 years old group and <70 years old group (P<0.05).The ratio of male to female was 1.27∶1,and gender difference was statistically significant(P<0.05).The occupation ratio of latent syphilis was 90.530%.
Conclusion
The positive rate of syphilis increases year by year.The positive rate of syphilis in>70 years old group was higher,and the syphilis ratio was the highest in the latent syphilis.There are many reasons for this result,such as age,geriatric disease factors,technical operation factors and syphilis serum immobilization factors.It is the sacred duty and mission of medical workers to popularize the serological screening of syphilis and to find out the patients of syphilis early,to analyze the results of the examination and to combine the clinical symptoms and early treatment to prevent the spread of the syphilis.
2018 Vol. 25 (22): 152-155 [
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] (
144
)
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156
Application effect of quality control circle in painless ward management during perioperative period of appendectomy
LUO Xiao-yan;YE Cui-yun;DENG Chun-hong
Objective
To explore the application effect of quality control circle in painless ward management during perioperative period of appendectomy.
Methods
All of 160 cases treated by appendectomy in our hospital from January to December in 2017 were divided into two groups according to the order of admission time.Among them,80 patients from January to June in 2017 were set up as the control group,and the group was given the routine nursing program.80 patients from July to December in 2017 were set up as the observation group,and the group was given quality control circle program.The score of pain knowledge,VAS score after 8,24,48 h operation and out of bed activity time and the satisfaction degree with analgesia service were compared in patients between the two groups.
Results
The score of pain knowledge and the total satisfaction rate with the management of analgesia in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The VAS scores after 8,24,48 h operation in the observation group was lower than those of the control group,and out of bed activity time in the observation group was shorter than that of the control group,and the differences were statistically significant(P<0.05).
Conclusion T
he quality control circle can effectively improve the management level of the painless ward in appendectomy,relieve postoperative pain and improve the patients′satisfaction degree with pain relief.It is worth further promoting in clinic.
2018 Vol. 25 (22): 156-158转164 [
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] (
132
)
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159
Application of 3D printing knee joint disease model based on MRI reconstruction technology in orthopaedics teaching
CHEN Wei-jian;CHEN Yi-xiong;CHEN Hui-hua
At present,the magnetic resonance three-dimensional printing model is widely used in clinical teaching.In orthopaedics teaching,MRI reconstruction techniques are combined with physical aids for 3D printing models for complex knee cases.Accurate and individualized teaching is conducted to allow students to simulate 3D printing models and develop specific the surgical plan helps to understand and master the etiology,diagnosis and treatment of knee-related diseases,understand and master the anatomy and spatial structure of the knee joints,and skillfully simulate the operation of the surgery,thereby realizing the goal of precision and individualized teaching.The magnetic resonance 3D printing model enables students to vividly and intuitively understand the anatomy of knee-related cases.It also enhances the interest of learning and the active level of classroom learning.It is conducive to enhancing the efficiency and quality of learning.The prospect of application is worth promoting and applying in orthopedic teaching.
2018 Vol. 25 (22): 159-161 [
Abstract
] (
142
)
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162
Application effect of standard operating procedures in professional technical operation training of disinfection supply center
SHI Yu-hua;WU Yan-hua;CHEN Xiao-si
Objective
To investigate the application effect of standard operating procedures in professional technical operation training of disinfection supply center.
Methods
From January to December in 2016,10 staffs from the Disinfection and Supply Center of the Second People′s Hospital of Jiangmen City were selected as the research group,they conducted professional technical operation training through standard operating procedures.From January to December in 2015,10 staffs from the disinfection and supply center of the Second People′s Hospital of Jiangmen City were selected as the control group,and they conducted professional and technical operation training through traditional means.The application effect of the two groups were compared.
Results
The excellent and good rate of professional technical operation examination in the study group was 96.0%,which was significantly higher than that of the control group (80.0%),with significant difference(P<0.05).The application compliance of the study group was 100.0%,which was significantly better than that of the control group(82.0%),with significant difference(P<0.05).
Conclusion
The application of standard operating procedures in the professional technical operation training of the disinfection supply center can increase the professional technical operation level of the staff,and at the same time can improve the staff′s compliance with the professional technical operation and training,and improve the overall work quality of the disinfection supply center.
2018 Vol. 25 (22): 162-164 [
Abstract
] (
130
)
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29
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165
Application value of improved PICC sealing technique combined with urokinase sealing in the intermission of chemotherapy for malignant tumors
ZHANG Yang-hua;HU yun;TONG Hui-qun
Objective
To explore the application value of improving Peripherally Inserted Central Venous Catheters(PICC)sealing technique combined with urokinase sealing in the intermission of chemotherapy for malignant tumors.
Methods
A retrospective analysis was made of 180 patients with malignant tumors treated with chemotherapy treated in our hospital from January 2016 to December 2017.They were divided into control group and observation group according to different sealing methods,with 90 cases in each group.The control group was given conventional sealing method while the observation group was given improved PICC sealing method combined with urokinase sealing method.The sealing effect of patients between the two groups was compared.
Results
Before the intervention,there was no statistical difference between the two groups(P>0.05).After the intervention,there was no statistically significant difference in coagulation system indexes between the two groups compared with those before the intervention(P>0.05).Moreover,there was no statistically significant difference in coagulation system index between the observation group and the control group after intervention (P>0.05).The incidence of tube blocking in the observation group was lower than that in the control group,the number of tube blocking and treatment cost were both lower than those in the control group,the catheter usage time was longer than that in the control group,and the patient satisfaction score was higher than that in the control group,and the difference was statistically significant(P<0.05).
Conclusion
The application of improved PICC sealing technique combined with urokinase sealing in patients with intermittent chemotherapy for malignant tumors has no obvious influence on the coagulation system of the patients.It can reduce the incidence of pipe plugging,reduce the treatment cost,prolong the use time of catheters,and improve the nursing satisfaction score.It is worthy of clinical popularization and application.
2018 Vol. 25 (22): 165-167转171 [
Abstract
] (
129
)
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168
Application value of traditional Chinese medicine nursing in rehabilitation of hemiplegic limbs in patients with stroke
HAN Yan;LIU Xiang-li;ZHANG Jing
Objective
To explore the application value of Traditional Chinese Medicine(TCM)nursing in promoting the rehabilitation of hemiplegic patients with stroke.
Methods
A tolal of 60 patients with hemiplegia after stroke admitted to our hospital from March to September 2017 were analyzed retrospectively.They were divided into control group and study group with 30 cases in each group according to nursing method.The control group was given routine nursing in department of neurology of rehabilitation department,while the research group was given TCM nursing for two weeks.The nursing effects of the two groups were observed and compared.NIHSS,Barthel index and Berg balance scale score were compared.
Results
The total effective rate for nursing of patients in the study group was higher than that in the control group,and the difference was statistically significant(P<0.01).Before nursing,there was no statistically significant difference in NIHSS score,Barthel index,Berg balance for nursing and limb function score between the two groups(P>0.05).After nursing,the NIHSS score of the study group was lower than that of the control group,Barthel index and Berg balance scale score were higher than those of the control group,and the differences were statistically significant(P<0.01).
Conclusion
Accepting traditional TCM for hemiplegic patients with stroke can obviously improve their daily life ability and limb movement function,improve the curative effect,and is worthy of clinical popularization.
2018 Vol. 25 (22): 168-171 [
Abstract
] (
152
)
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172
The effect of clinical nursing pathway on improving risk management effect of patients with acute schizophrenia
CEN Hong-zhou;LI Yu-mei;HUANG Wen-hua
Objective
To explore the influence of clinical nursing pathway on improving the risk management effect of patients with acute schizophrenia.
Methods
A total of 200 patients with acute schizophrenia admitted into our hospital from January to December 2017 were randomly divided into control group and study group,and there were 100 patients in each group.The control group was given routine psychiatric care,and the research group was given clinical nursing pathway management on this basis.The CGI-S1 score,violence risk score,suicide or self-injury risk score,and risk score of leaving the hospital without permission were compared in patients between the two groups.
Results
There was no significant difference in CGI-S1 score between the two groups before implementation (P>0.05).After implementation,the CGI-S1 score of patients in the study group was significantly lower than that of the control group,and the CGI-S1 score of patients in the study group was significantly lower than that before implementation,and the differences were statistically significant(P<0.05).There was no significant difference in CGI-S1 score,before implementation,between the two groups(P>0.05).After implementation,the violence risk score in the study group was significantly lower than that in the control group,and the violence risk score in the study group was significantly lower than that before implementation,and the differences were statistically significant(P<0.05).There was no statistically significant difference in the violence risk score between the control group in the control group (P>0.05).Before implementation,there was no statistically significant difference in the risk score of suicide or self-injury between the two groups(P>0.05).After implementation,the violence risk score in the study group was significantly lower than that in the control group,and the two groups violence risk score in the study group was significantly lower than that before implementation,and the differences were statistically significant(P<0.05).There was no significant difference in the risk score of suicide or self-injury between the control group and the control group(P>0.05).Before implementation,there was no significant difference between the two groups(P>0.05).After implementation,the risk score of patients in the study group was significantly lower than that in the control group,and the risk score of patients in the study group was significantly lower than that before implementation,and the differences were statistically significant(P<0.05).There was no statistically significant difference between the risk scores of patients in the control group before and after implementation(P>0.05).
Conclusion
The implementation of CNP can reduce nursing the risk of nursing,the implementation of CNP can reduce the risk of nursing,ensure the safety of patients and improve the clinical curative effect,and also increase clinical efficacy.
2018 Vol. 25 (22): 172-175 [
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139
)
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176
Effect of liquid dressing in the prevention of skin pressure injury in patients undergoing lateral position surgery
HUANG Ming-fu;OUYANG Hui-xian; CHEN Zhuo-hua;LU Fu-feng;WANG Dong-quan
Objective
To investigate the effect of liquid dressing(seborrhea)on preventing skin pressure injury in patients undergoing lateral position surgery.
Methods
From January 2014 to June 2017,100 patients with lateral position surgery in our hospital were selected and divided into control group and experimental group by random number table method,with 50 patients in each group.The control group was given routine stress injury prevention nursing and did not take any other measures.On the basis of routine nursing,the experimental group was sprayed with liquid dressing on the skin under pressure before operation and gently massaged with fingertips clockwise for 1 min.After the operation,the total incidence of skin pressure injury in the two groups was observed when swinging back to the supine position.
Results
The total incidence of skin pressure injury in the experimental group was significantly lower than that in the control group,the difference was statistically significant(P<0.05).
Conclusion
Liquid dressing can effectively reduce skin pressure injury and its total incidence in patients undergoing lateral position surgery.It is worthy of popularization.
2018 Vol. 25 (22): 176-178 [
Abstract
] (
138
)
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23
)
179
Clinical study on the effect of nursing evaluation meeting on rehabilitation of patients with tibia and fibula fracture after operation
LI Yi;GAO Yan;WANG He-qiang;WU Yu-jian;LIU Bing;CHEN Guo;CHEN Mu-sheng;ZHANG Jian-li;ZHENG Yu-qin
Objective
To explore the influence of nursing evaluation meeting on the rehabilitation of patients with tibia and fibula fracture after operation.
Methods
From March 2016 to December 2017,60 postoperative rehabilitation patients with tibia and fibula fracture treated in our hospital were selected and divided into control group and observation group according to the order of admission,with 30 patients in each group.The control group was given routine nursing.The observation group evaluated the patients on the basis of the control group and organized responsible nurses to carry out nursing evaluation meetings.After 2 months of intervention,the rehabilitation status of the two groups of patients was compared.
Results
After nursing,the average hospitalization time in the observation group was shorter than that in the control group,and the average daily hospitalization expense was lower than that in the control group,and the differences were statistically significant(P<0.05).There was no significant difference between the two groups in Brathel index scores before nursing (P>0.05).After nursing,the Brathel index scores of the two groups of patients were higher than those before nursing,and the Brathel index scores of the observation group were higher than those of the control group,after nursing,and the difference was statistically significant(P<0.05).After nursing,the total satisfaction degree of patients in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).
Conclusion
Nursing evaluation meeting can not only improve the quality of rehabilitation care management,but also promote the recovery of postoperative patients with tibial fractures.It is worthy of clinical promotion.
2018 Vol. 25 (22): 179-181转190 [
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] (
151
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22
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182
Effect of cooperative nursing and functional exercise on quality of life and self-care ability of rheumatoid arthritis patients
HU Qiu-xia
Objective
To explore the effect of cooperative nursing and functional exercise on the quality of life and self-care ability of rheumatoid arthritis(RA)patients.
Methods
A total of 88 patients with rheumatoid arthritis admitted to our hospital from June 2016 to June 2017 were selected and divided into control group and observation group according to different nursing methods,with 44 cases in each group.The control group was given routine nursing while the observation group was given cooperative nursing and functional exercise.The quality of life,self-care ability and nursing satisfaction of the two groups of patients after nursing were compared.
Results
There was no significant difference in GQOLI-74 scores between the two groups before nursing(P>0.05).The GQOLI-74 scores of patients in the two groups after nursing were higher than those before nursing,and the GQOLI-74 scores of patients in the observation group were significantly higher than those in the control group,the differences were statistically significant(P<0.05).There was no significant difference in barthel index score between the two groups before nursing (P>0.05).The Barthel index scores of the two groups of patients after nursing were higher than those before nursing,and the Barthel index scores of the patients in the observation group were significantly higher than those in the control group,the difference was statistically significant(P<0.05).The total satisfaction degree of patients in the observation group was higher than that in the control group,and the differences were statistically significant(P<0.05).
Conclusion
Collaborative nursing care and functional exercise have a significant effects in the clinical nursing care in the patients with rheumatoid arthritis,which can significantly improve the quality of life of patients and self-care ability,and can improve nursing satisfaction.It is worthy of promotion.
2018 Vol. 25 (22): 182-184 [
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155
)
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Comparison of the application effects of hand forward extension,ball holding and sleep posture in chest surgery
FAN Yi-shen;CHEN Ya;DENG Jiang-bo;CHEN Xiong-fen;WU Guo-hai
Objective
To investigate the effect of hand forward extension,ball-holding and sleep posture in thoracic surgery.
Methods
A total of 186 cases of thoracic surgery patients admitted to our hospital from January 2015 to December 2017 were selected as research objects.They were divided into the hand extension group,the ball holding group and the sleep group with 62 cases in each group by random number table method.Patients in the hand stretching group used both hands to stretch forward and put the posture,patients in the ball holding group used the ball holding posture,and patients in the sleep type group used the sleep type posture.The placement time,operation time and postoperative complications of the three groups of operation positions were compared,and the satisfaction of the staff participating in the placement was evaluated from the perspectives of labor saving and convenient operation.
Results
The placement time and operation time were the shortest in the sleep-posture group,followed by the ball-holding group,and the longest time was displayed in the hand-protraction group with statistical significance among the three groups(P<0.05).The total incidence of postoperative complications was the lowest in the sleep-posture group,followed by the ball-holding group,and the highest incidence was in the hand-protraction group,which were displayed significant differences among the three groups (P<0.05).The satisfaction of labor saving and convenience on sleep-posture by the staff was highest,followed by the ball-holding group,worst in the hand-protraction group with statistical significance(P<0.05).
Conclusion
Among the three kinds of posture placement methods,the sleep group patients′posture has the best effect in chest surgery and is worth popularizing.
2018 Vol. 25 (22): 185-187 [
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153
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188
Effect of continuous nursing on patients with heart failure
HUANG Qiong-yi;DENG Yu-fen;HUANG Yi-lin
Objective
To explore the effect of continuous nursing in patients with heart failure.
Methods
A total of 120 hospitalized patients with heart failure admitted to our hospital from January 2016 to July 2017 were selected and divided into control group and nursing group according to the order of treatment,with 60 cases in each group.The control group received routine nursing intervention while the nursing group received continuous nursing intervention.The selfcare ability (SCHFI)and health behavior(HPLP)scores were compared between the two groups one day before discharge and 1,3,6 months after discharge,and the recurrence rate of heart failure in the 6-month follow-up period after discharge was counted.
Results
There was no significant difference in SCHFI score between the two groups before discharge (P>0.05).SCHFI scores of patients in the nursing group were higher than those in the control group at 1,3 and 6 months after discharge,and the difference was statistically significant(P<0.001).There was no significant difference in HPLP scores between the two groups before discharge (P>0.05).The HPLP scores of patients in the nursing group were higher than those in the control group at 1,3 and 6 months after discharge,and the difference was statistically significant(P<0.001).The recurrence rate of heart failure in the nursing group was significantly lower than that in the control group after one month of nursing,one to three months of discharge,and three to six months of discharge,and the difference was statistically significant(P<0.05).
Conclusion
The application of continuous nursing in patients with heart failure can obviously improve their self-care ability and health behavior level,and obviously reduce the acute attack of heart failure.
2018 Vol. 25 (22): 188-190 [
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122
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191
Effect of structured skin care on prevention of incontinent dermatitis in fecal incontinence patients
PAN Yue-zhi;XU Yu-Jing;XIE Xiao-li
Objective
To explore the effect of structured skin care in preventing incontinent dermatitis in fecal incontinence patients.
Methods
A total of 180 fecal incontinence patients admitted to our hospital from January 2016 to December 2017 were selected as research objects,and they were randomly divided into control group and research group,with 90 cases in each group.The control group received routine nursing while the study group received structured skin nursing.The occurrence of incontinent dermatitis,pressure sores,satisfaction score,pain score and complications were compared between the two groups.
Results
The total incidence of incontinent dermatitis in the study group was significantly lower than that in the control group the difference was statistically significant(P<0.05).The total incidence of pressure sores in the study group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).The satisfaction score of the patients in the study group was significantly higher than that of the control group,and the pain score was significantly lower than that of the control group,the difference was statistically significant(P<0.05).The total incidence of complications in the study group was significantly lower than that in the control group,the difference was statistically significant(P<0.05).
Conclusion
Structured skin care can significantly reduce the incidence of incontinent dermatitis,pressure sores and complications in fecal incontinence patients,significantly reduce the degree of pain in patients and improve patient satisfaction.
2018 Vol. 25 (22): 191-193 [
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141
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194
Effect of early nursing intervention in patients with macular edema
WEN Jian-nv;TAO Zhu-jin
Objective
To explore the effect of early nursing intervention in patients with macular edema.
Methods
A total of 70 patients with macular edema admitted to our hospital from June 20,2015 to May 20,2017 were selected as the research objects,and were randomly divided into routine group and experimental group by envelope grouping scheme,with 35 cases in each group.All patients were given intravitreal injection therapy,the routine group was given the general nursing plan and the experimental group was given early nursing intervention,the nursing effects of patients of the two groups were compared.
Results
The total effective rate of treatment in the patients in the experimental group was higher than that in the conventional group,and the difference was statistically significant(P<0.05).The total incidence of complications in the experimental group was significantly lower than that in the routine group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in SAS score between the two groups before nursing (P<0.05).After nursing,the SAS score of the two groups were lower than those before nursing,and the SAS score of the experimental group were significantly lower than those of the routine group after nursing,and the differences were statistically significant(P<0.05).After nursing,the quality of life scores of patients in the experimental group were significantly higher than those in the routine group,and the difference was statistically significant(P<0.05).
Conclusion
Early nursing intervention for macular edema patients is convenient to achieve good clinical application effect,has a higher safety,and is convenient to improve the daily life quality of patients.
2018 Vol. 25 (22): 194-196 [
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132
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197
Role of nursing risk quality management in reducing nosocomial infection rate of ICU patients
Objective
To explore the role of nursing risk quality management in controlling the hospital feeling of ICU inpatients.
Methods
A total of 138 ICU inpatients admitted to our hospital from February 2017 to February 2018 were selected as the research object,69 patients from February to July 2017 were taken as the control group,and 69 patients from August 2017 to February 2018 were taken as the observation group,and nursing risk quality management was adopted.The ICU infection rate,hand hygiene compliance rate,ICU department environment and effect monitoring were compared between the two groups.
Results
The ICU infection rate of patients in the observation group was 1.45%,which was significantly lower than that of the control group (10.14%),the difference was statistically significant(χ
2
=4.777,P=0.029).The hand hygiene compliance rate of the nursing staff in the observation group before and after contact with patients was higher than that of the control group,the difference was statistically significant(P<0.05),while the hand hygiene compliance rate of the two groups of nursing staff before aseptic operation was not statistically significant compared with that of blood and liquid exposure(P>0.05).The qualified rate of environment and effect test in ICU department of observation group was obviously higher than that of control group,and the difference was statistically significant(P<0.05).
Conclusion
The quality management of nursing risk starts with the training of nursing staff,the attention of hand hygiene,aseptic operation and ICU indoor environment.It is flexible to take effective training on infection knowledge,improve the management system,and effectively control the occurrence of nosocomial infection.
2018 Vol. 25 (22): 197-199 [
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125
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200
Application effect of family-free nursing model in the Anorectal Department
CAI Wan-zhu
Objective
To explore the application effect of family-free nursing model in the Anorectal Department.
Methods
A total of 60 anorectal patients admitted to our hospital from December 2015 to December 2016 were selected as the research objects,and divided into nursing group 1 and nursing group 2 according to whether the patients were accompanied by their family members,each group consisted of 30 patients.Nursing group 1 was given the family-free nursing mode and nursing group 2 was given the routine nursing mode.The nursing quality,hospital infection,selfmanagement,nursing compliance and the incidence of adverse events were compared between the two groups.
Results
The related nursing quality scores of patients in group 1 were significantly higher than those in group 2,and the difference was statistically significant(P<0.05).The total compliance rate of patients in group 1 was significantly higher than that in group 2,and the difference was statistically significant(P<0.05).The total accident rate of patients in nursing group 1 was significantly lower than that in nursing group 2,and the difference was statistically significant(P<0.05).
Conclusion
The application of family-free nursing mode in anorectal department can significantly improve the patient's nursing compliance and reduce the incidence of adverse events,thus improving the patient's management behavior,improving the patient's nursing quality,ward management and hospital infection control.this method is worthy of application and promotion.
2018 Vol. 25 (22): 200-202 [
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161
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203
Effect of individual nursing intervention on improvement of sleep and quality of life in patients with chronic kidney disease
WU Yu-ting;HUANG Li-juan;YAN Qin;YU Min;ZENG Wen-yu
Objective
To explore the effect of individual nursing intervention on the improvement of quality of sleep and quality of life in patients with chronic kidney disease.
Methods
A total of 134 cases patients with chronic kidney disease in our hospital from June 2015 to June 2016 were selected.According to the different nursing methods,all the patients were divided into the observation group and the control group,67 cases in each group.The control group was given routine nursing intervention,and the observation group was given individual nursing intervention on the basis of the control group.The PSQI score and the SF-36 scale were compared between the two groups in order to evaluate the quality of sleep and the quality of life.
Results
The PSQI score of the observation group was(3.52±2.12)points,which was significantly lower than that of the control group of(6.84±4.02)points(P<0.05).The general health status,physiological function,mental health,social function,emotional function and somatic pain scores in the SF-36 scale of the observation group were significantly better than those in the control group,the differences were statistically significant(P<0.05).
Conclusion
Individualized nursing intervention can significantly improve quality of sleep and quality of life on patients with chronic kidney disease,and can be used as the preferred mode of nursing intervention for patients with chronic kidney disease.
2018 Vol. 25 (22): 203-205 [
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199
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206
The influence of airway nursing on respiratory tract infection and inflammatory indexes in children with severe pneumonia
CHENG Xue;GUO Juan
Objective
To explore the influence of airway nursing on respiratory tract infection and inflammatory indexes in children with severe pneumonia.
Methods
A total of 88 children with severe pneumonia admitted to our hospital from January 2016 to January 2017 were selected as research objects,and were divided into control group and observation group with 44 cases in each group by random number table method.The control group was given routine nursing,while the observation group was given airway nursing on the basis of routine nursing.The incidence of respiratory tract infection and changes of inflammatory indexes were compared between the two groups.
Results
The incidence of respiratory tract infection in the observation group was lower than that in the control group,the difference was statistically significant(χ
2
=4.019,P<0.05).Before the intervention,there was no statistical difference between the two groups(P>0.05).After the intervention,the levels of inflammatory indicators in the two groups of children were lower than those before the intervention,and the levels of inflammatory indicators in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).The disappearance time of clinical symptoms such as cough,lung rale and dyspnea in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).
Conclusion
Airway care in children with severe pneumonia helps to reduce the incidence of respiratory tract infections and the level of inflammatory indexes,then improve the clinical symptoms of children.
2018 Vol. 25 (22): 206-208 [
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142
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209
Influence of high quality nursing intervention on health knowledge cognition and psychological state of patients undergoing laparoscopic cholecystectomy
SU Yun-bo;WANG Mei-ping;ZHOU Ren-mei
Objective
To explore the influence of high quality nursing intervention on health knowledge cognition and psychological state of patients undergoing laparoscopic cholecystectomy(LC).
Methods
A total of 120 LC patients admitted to our hospital from June 2015 to May 2017 were selected,60 patients who received routine nursing from June 2015 to May 2016 were selected as the control group,and 60 patients who received high-quality nursing intervention from June 2016 to May 2017 were selected as the observation group.The changes of health knowledge cognition and psychological state of patients of the two groups were compared and analyzed.
Results
The health cognition scores of patients in the observation group were higher than those in the control group at the time of discharge,and the difference was statistically significant(P<0.05).Before the intervention,there was no significant difference in SAS and SDS scores between the two groups(P>0.05).After the intervention,the scores of SAS and SDS in the two groups were lower than those before the intervention,and the scores of SAS and SDS in the observation group were lower than those in the control group,the difference was statistically significant(P<0.05).
Conclusion
High quality nursing intervention for LC patients can significantly improve patients′negative emotion and increase health knowledge cognition.
2018 Vol. 25 (22): 209-211 [
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154
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212
Application of high quality nursing model in perioperative nursing of thyroid surgery patients
XIONG Ming-gui;FANG Jia
Objective
To explore the application value of high quality nursing model in perioperative nursing of thyroid surgery patients.
Methods
A total of 38 patients undergoing thyroid surgery in our hospital from January to December 2016 were selected as the control group,and 38 patients undergoing thyroid surgery in our hospital from January to December 2017 were selected as the observation group.The control group was given routine nursing intervention,while the observation group was given high-quality nursing intervention based on this.The nursing satisfaction,SAS and SDS scores and the incidence of total adverse reactions were compared between the two groups.
Results
The total satisfaction of the observation group after nursing was higher than that of the control group,and the difference was statistically significant(P<0.05).The scores of SAS and SDS in the two groups after nursing were lower than those before nursing,and the scores of SAS and SDS in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).The total incidence of adverse reactions after nursing in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).
Conclusion
For patients undergoing thyroid surgeries,the use of high-quality nursing mode in their perioperative care has an important value and role in improving the patient′s bad psychological status,increasing satisfaction,and reducing the incidence of adverse reactions.Therefore,it can be promoted in clinical practice.
2018 Vol. 25 (22): 212-214 [
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144
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Application effect of pregnant women′s school in nursing of patients with gestational diabetes
ZHOU Ya-fei;LI Cong-hui;DU Kang
Objective
To explore the role of pregnant women′s school in relieving the psychological pressure of gestational diabetes.
Methods
Ninety-six gestational diabetes patients admitted to our hospital from January to November 2017 were selected and divided into control group and observation group with 48 cases in each group by random number table method.The control group was given routine nursing,while the observation group was given nursing by the school model for pregnant women.The nursing satisfaction,the incidence rate of complication,anxiety,depression score,sleep quality score and life quality score of the two groups were compared.
Results
The total satisfaction degree of patients in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).The incidence of complications in the observation group was lower than that in the control group,the difference was statistically significant(χ
2
=7.901,P=0.005).Before the intervention,there was no significant difference in anxiety score,depression score,sleep quality score and quality of life score between the two groups(P>0.05).After the intervention,the anxiety score,depression score,sleep quality score and life quality score of the observation group were all better than those of the control group,and the differences were statistically significant(P<0.05).
Conclusion
The pregnant school nursing model can effectively relieve the psychological and physiological state of the pregnant patients and reduce the risk of complications.It has a higher clinical value.
2018 Vol. 25 (22): 215-217 [
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138
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Effect of risk management defense mechanism on nursing safety in emergency rescue
ZHANG Xiao-rong;HUANG Jing;HE Zhen-jiao
Objective
To investigate the effect of risk management defense mechanism on nursing safety in emergency rescue.
Methods
The clinical data of 60 critical patients in the emergency department from June to October 2017 were retrospectively analyzed.All the patients were divided into two groups by management modes,30 cases in each group.The control group was given routine emergency nursing,while the observation group was given risk management defense mechanism of nursing safety based on control group.The rescue success rate,incidence of complications,nursing error rate,rescue time,cardiopulmonary resuscitation time,intubation time,hospital stays,risk events,risk management of nursing staff and nursing satisfaction were compared between the two groups.
Results
The incidence of complications,nursing error rate in observation group[3.33%,3.33%]were lower than that in the control group[26.67%,30.00%](P<0.05).There was no statistical difference in the rescue error rate between the two groups(P>0.05).The rescue time,cardiopulmonary resuscitation time,intubation time in the observation group([30.82±11.49],[3.29±2.04],[5.42±2.18]min)were shorter than than in the control group([42.67±12.95],[5.58±2.67],[8.26±3.12]min)(P<0.05).The total incidence of risk events in the observation group(6.67%)was lower than that in the control group(26.67%)(P<0.05).The scores of risk awareness,acquaintance of risk management,behavior consciousness,attitude in the observation group([22.56±2.25],[23.68±1.29],[21.49±2.46],[20.18±2.47]points)were higher than that in the control group([17.92±3.54],[18.46±4.82],[15.96±3.58],[14.74±4.55]points)(P<0.05).The total satisfaction of the observation group(93.33%)was higher than that in the control group(70.00%)(P<0.05).
Conclusion
The application of risk management defense mechanism of nursing safety in emergency rescue is effective,it can increase the risk awareness of nursing staff,reduce risk events and promote satisfaction.
2018 Vol. 25 (22): 218-220 [
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150
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