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2017 Vol. 24, No. 18
Published: 2017-06-28
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Expression of Oral pCDNA3.1+/Ag85A DNA vaccine in the intestine of mice
XU Jia;LIU Ying;YU Miao;FENG Yong-hui;LYU Chang-long
ObjectiveTo analyze the expression of oral pCDNA3.1+/Ag85A DNA vaccine in the intestinal tract of mice.MethodsOral vaccine was made using liposomes to parcel pCDNA3.1+/Ag85A DNA plasmid.5 female C57BL/6 mice in control group were given saline water for gavage while 5 female C57BL/6 mice in experimental group were given liposome encapsulated Ag85A DNA vaccine for gavage.The mice were immunized three times with 14 days interval between each time.In the fourteenth day after immunization,cervical dislocation executed in mice and the small intestine was fixed with 4%paraformaldehyde to be prepared to detect the expression of Ag85A in the intestinal Peyer patches,the dendritic cells in Peyer patches and intestinal epithelial cells with immunofluorescence and immunohistochemistry methods.ResultsOral vaccine pCDNA3.1+/Ag85A DNA was expressed in intestinal Peyer patches,the dendritic cells in Peyer patches and the intestinal epithelial cells of mice in the experimental group,and in different parts of the intestinal epithelial cells in mice of the experimental group,the expression intensity of Ag85A was different.The expression intensity of Ag85A was higher near the lamina propria than near the lumen of intestinal epithelial cells(P＜0.05).It was not expressed in above parts of mice in the control group.ConclusionOral DNA vaccine parceled with liposomes can be absorbed by intestinal tract of mice and induce specific mucosal immune response.
2017 Vol. 24 (18): 4-7 [
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Influence of snoRNA-derived pi-sno81 on FOXO3a expression in breast cancer
CHEN Xin-xin;HU Xiao-wu;XIA Ting CAO;Teng-fei;JIA Hai-xia;ZHANG Le-hong
ObjectiveTo investigate the influence of snoRNA-derived piRNA on FOXO3a gene in breast cancer.MethodsFive chemically synthesized pi-snoRNAs including pi-sno44,pi-sno74,pi-sno75,pi-sno78,and pi-sno81 were transfected into MDA-MB-231 breast cancer cells and the total RNA was extracted.EachpiRNA was detected in order to find its influence on FOXO3a mRNA levels as well as the most effective piRNA on FOXO3a,and then testified its influence on FOXO3a level.The fresh tumor and peritumoral specimen in 28 pairs in breast cancer patients undergone the radical surgery of the mammary gland in our department from March to October in 2016 were collected.Among them,expressions of pi-sno81,sno81,and FOXO3a were detected.Expressions of pi-sno81,sno81,and FOXO3a in breast cancer and adjacent mammary gland tissue were in correlation analysis aiming at understanding the correlation of pi-sno81and FOXO3a by canonical correlation analysis.ResultsqRT-PCR detected the expression of FOXO3a was up-regulated by pi-sno44,pi-sno74,pi-sno75,and pi-sno81,of which pi-sno81 was in most remarkable on up-regulating FOXO3a.Besides,pi-sno81 greatly up-regulated the protein level of FOXO3a,a low expression in breast cancer.Correlation analysis detected that expression of pi-sno81 in breast cancer and adjacent mammary gland tissue was in positive correlation with FOXO3a in expression of breast cancer and adjacent mammary gland tissue(P<0.001,Corr=0.835).ConclusionThe snoRNA-derived pi-sno81 can up-regulate the expression of FOXO3a gene in breast cancer cells,and may affect the growth of breast cancer cells by influencing FOXO3a expression.
2017 Vol. 24 (18): 8-12 [
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Patient privacy protection situation and countermeasures in China
LIU Xiao-chen;TIAN Li-juan;WANG Chang
This paper mainly summarizes the progress of the patients privacy protection of China and other countries and analyze the current patients privacy protection situation of our country,namely:the imperfect privacy protection legal system,the lack of a clear supervision mechanism and compensation standard and lack of privacy protection awareness in medical staff.On the basic of above discussion,the writer puts forward the suggestions and countermeasures of patient privacy protection.
2017 Vol. 24 (18): 13-15转27 [
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Study on the manufacture homemade mask head strap for noninvasive ventilation on improving patient compliance
XIAO Yan;XIAO Bing;LYU Xu-ying;LIANG Hai-hua
ObjectiveTo study the manufacture homemade mask head strap for noninvasive ventilation on improving patient compliance.Methods40 patients in our hospital from June 2016 to March 2017 were randomly divided into study group and control group,with 20 patients in each group.The study group was given manufacture homemade mask head strap for noninvasive ventilation,while the control group was given traditional noninvasive ventilator mask head strap.The compliance rates,discharge rates,complication rates,ventilator using time and hospital stay were compared between the two groups.ResultsThe compliance rate in the study group(95.0%)was higher than that in the control group(70.0%),and the discharge rate(90.0%)was higher than that in the control group(60.0%),while the compliance rate(15.0%)was lower than that in the control group(45.0%),and the ventilator using time[(3.8±0.7)d]and hospital stay[(8.3±2.1)d]were shorter than those in the control group [(6.1±1.2),(15.3±4.6)d],and the differences in these indexes were significant(P<0.05).ConclusionThe application of manufacture homemade mask head strap for noninvasive ventilation can improve the patient′s compliance with the use of ventilator,speed up rehabilitation.
2017 Vol. 24 (18): 16-18 [
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Practice and evaluation of first treatment and post transportation curing acute myocardial infarction
LI Xiao-lei
ObjectiveTo explore the effect of first treatment and post transportation curing acute myocardial infarction and its influence on the prognosis.MethodsA retrospective analysis was conducted.From October 2016 to May 2017,128 patients with acute myocardial infarction treated by different the first aid way before hospital were selected.According to the first aid way before hospital,patients were divided into the three groups.Group A was sent into the emergency department of our hospital by the family members,and group B was transferred to our hospital by emergency personnel to conduct the cure,and group C was transferred to our hospital immediately after emergency treatment.The time of from the attack to start the cure,the thrombolysis time,the total mortality and the improvement rate of disease among the three groups were compared,and the heart rate,respiration and blood pressure of survival patients after curing among the three groups were compared,and the total satisfaction degree among the three groups were compared.ResultsThe time of from the attack to start the cure,the thrombolysis time and the mortality in group C were significantly lower than those of group A and group B(P<0.05)and the improvement rate of disease in group C was significantly higher than those of group A and group B (P<0.05).There was a statistical difference of heart rate and respiratory rate among the three groups(P<0.05).Compared with group A and group B,the total satisfaction degree(98%)of patients in group C was the highest(P<0.05).ConclusionThe curing acute myocardial infarction can shorten the cure time and thrombolysis time,derease the mortality rate,improve the treatment effect and treatment satisfaction degree,and improve the prognosis state of heart rate and respiratory.
2017 Vol. 24 (18): 19-21 [
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Effect of early enteral nutrition on T cell subsets and cytokines in patients with acute exacerbation of COPD complicated with respiratory failure
ZHANG Hua-gen
ObjectiveTo investigate the effect of early enteral nutrition on T cell subsets and cytokines in patients with acute exacerbation of COPD complicated with respiratory failure.MethodsFrom September 2013 to December 2016,86 patients with acute exacerbation of COPD complicated with respiratory failure were enrolled in this study.86 patients were randomly divided into two groups:two groups were given routine ventilator-assisted ventilation,and 42 patients in the control group were given the parenteral nutrition support after 24 hours mechanical ventilation,while 44 patients in the observation group were given the enteral nutrition,14 days were a course of treatment.The curative effect between two groups was compared.ResultsAfter treatment,the level of tumor necrosis factor(TNF-α)and interleukin-6(IL-6)were decreased,and the value of CD4+,CD3+,CD4+/CD8+were lower in the observation group,but the observation group was higher than the control group respectively(P<0.05).The incidence rate of double infection,liver function damage,gastrointestinal bleeding and blood sugar increase and mortality in the observation group were lower than those in the control group(P<0.05).ConclusionEarly application of enteral nutrition in COPD patients with acute exacerbation of respiratory failure can promote disease rehabilitation,prevent immune function damage and reduce the incidence of complications,and it is worthy of population.
2017 Vol. 24 (18): 22-24 [
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Clinical effect analysis of Decitabine combined with pre-excitation regimen in the treatment of senile myelodysplastic syndrome
PENG Li
ObjectiveTo evaluate the clinical effect of Decitabine combined with pre-excitation regimen in the treatment of senile myelodysplastic syndrome.Methods55 elderly patients with myelodysplastic syndrome who were admitted into our hospital from June 2012 to January 2017 were selected as the study objects.All patients were numbered and randomly divided into two groups,and there were 30 patients in the control group,and 25 patients in the observation group.The patients in the control group were given pre-excitation regimen,while the observation group was given Decitabine combined with pre-excitation regimen.The clinical efficacy of patients between the two groups after treatment were compared.ResultsThe total effective rate was 96.00%in the observation group,which was significantly higher than that in the control group(66.67%)and the observation group had a better curative effect(P<0.05).The incidence of adverse reactions such as impaired liver function,thrombocytopenia and granulocytopenia in the observation group was significantly lower than those in the control group(P<0.05).ConclusionClinical effect of Decitabine combined with pre-excitation regimen in the treatment of senile myelodysplastic syndrome has a significant effect,which is helpful to eliminate the clinical symptoms of patients and promote the recovery of patients as soon as possible,and has an important clinical value.
2017 Vol. 24 (18): 25-27 [
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Effect of pterygium excision combined with limbal stem cell transplantation surgery treating pterygium
WU Qing-wei;WU Zhi-qun;LIN Shu-yan
ObjectiveTo observe the effect of pterygium excision combined with limbal stem cell transplantation surgery treating pterygium.Methods50 patients with pterygium treated in our hospital from April 2016 to January 2017 were selected including 81 eyes.They were divided into two groups by random number table method,and the observation group including 40 eyes and they were treated with simple pterygium excision combined with conjunctival autograft with limbal stem cells surgery while the control group including 41 eyes,and they were treated with simple pterygium excision.The efficacy between the two groups were compared.ResultsThe BUT in after 1 and 3 months operation in the two groups had no statistically difference compared with before operation(P<0.05).The BUT in the control group was shorter than that before operation after 5 days operation,and there was a statistically difference(P<0.05).After 5 days operation,the BUT between the two groups had a significant difference(P<0.05).The t-HOA after 1,3 months operation were significantly lower than that before operation(P<0.05).The proportion ofⅢ-Ⅳ grade of the observation group was lower than that of the control group (5.0%vs.21.9%)(P<0.05).ConclusionSimple pterygium excision combined with limbal autograft conjunctival flap transplantation operation has a reliable effect,and it helps to improve the visual quality.
2017 Vol. 24 (18): 28-30 [
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The short term efficacy of body ingredient element constituent by the body weight management in patients with simple obesity
LIU Lin;LIU Guang-yin;JIA Hong;SHI Gui-hua;HE Jing-wei;XU Hou-jun
ObjectiveTo detect the effect of the weight management by the human body composition analysis in patients with simple obesity.Methods70 patients with simple obesity were collected from January 2015 to January 2016 during the treatment of nutritional therapy in Tangshan Gongren Hospital prospectively,which the body composition was analyzed by BIA method,and according to the comprehensive analysis of body composition,muscle fat,abdominal fat after using non drug standard nutrition intervention the obesity were been intervened by the weight management for 3 months,and the patients were personalized dietary guidance,exercise guidance,interactive guidance and psychological behavior guidance on experimental object comprehensive weight loss intervention.The weight index were detected and compared before and after intervention:chest circumference and waist,hip circumference,body weight,body weight index;body composition index:basal metabolic rate and fat yield,fat free mass index,body moisture,muscle mass,total energy consumption.ResultsAfter the management for 3 months,all of the chest circumference,waist circumference,hip circumference,body weight and body mass index were significantly decreased than before(P<0.05).After the management for 3 months,the muscle mass,the basal metabolism,the total energy consumption and the fat free mass index were increased(P<0.05);the fat rate was decreased significantly (P<0.05).And there was no significant difference in body moisture (P>0.05).ConclusionWeight management can effectively reduce the weight of obesity,and improve the basic metabolism,the total energy consumption,lean muscle mass,body mass index,and maintain the body moisture,and reduce the fat rate.
2017 Vol. 24 (18): 31-33 [
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Analysis of the anastomotic leakage after one-stage repair of esophageal atresia and tracheoesophageal fistua
LI Le;YU Jia-kang;ZHONG Wei;HE Qiu-ming;ZENG Jia-hang;XIA Hui-min
ObjectiveTo discuss the causes,treatments and prognosis of anastomotic leakage after one-stage repair of esophageal atresia(EA)and/or tracheoesophageal fistula(TEF).Methods168 EA and/or TEF cases with one-stage repair in this medical center from January 2007 to January 2017 were retrospectively studied.Relevant factors such as the incidence of leakage,the potential cause and the prognosis of these cases were investigated.ResultsIn 168 cases,36 cases(21.43%)suffered leakage postoperation.Among them,8 leakage(22.22%)occurred in 4 days postoperation,26 leakage(72.22%)occurred between 5 days and 10 days,and 2 leakage(5.56%)occurred after 10 days(P<0.05).Underwent treatment,19 cases(52.78%)recovered in 1-2 weeks,11 cases(30.56%)recovered in 2-4 weeks,and the other 4 cases(11.11%)recovered in 4-6 weeks.Among the 43 cases of typeⅢa,22 cases(51.16%)suffered leakage,however,among the 117 caese ofⅢb,only 14 cases(11.97%)suffered leakage,which had significant difference(P<0.05).Patients with different birth weight,congenital cardiac abnormalitis,gastroesophageal reflux and anastomotic stricture had different incidence of anastomotic leaking,but there was no statistically significant difference(P>0.05).ConclusionAnastomotic leakage usually occurs between 5-10 days postoperation.The Gross classification is the influence factor of the incidence of anastomotic leakage after one-stage repair of EA and/or TEF.Most of the anastomotic leakage recovered in 4 weeks postoperation after conservative treatments.
2017 Vol. 24 (18): 34-37 [
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Influence of different blood Glu cose control programs on prognosis and blood Glu cose in patients with intracerebral hemorrhage after operation together with stress hyperglycemia
YANG Wei-jie;LI Xiao-yue;SONG Gang
ObjectiveTo investigate influence of different blood glucose control programs on prognosis and blood glucose in patients with intracerebral hemorrhage after operation together with stress hyperglycemia.MethodsA retrospective study was conducted,and 52 patients with stress hyperglycemia after cerebral hemorrhage in our hospital from June 2015 to May 2016 were divided into group A (n=25)and group B (n=27)according to different blood glucose control programs.Group A was treated with intravenous bolus injection,and group B was treated with continuous intravenous pump.The 28 d survival rate,the Glasgow outcome score,the blood glucose compliance rate,the standard time,the frequency of blood glucose monitoring,the incidence rate of hypoglycemia,blood glucose levels and blood glucose variability indexes were compared between the two groups.ResultsThere was no significant difference in 28 d survival rate,the blood glucose compliance rate,the standard time,the incidence rate of hypoglycemia between the two groups (P＞0.05).The Glasgow outcome score in group A was significantly higher than that in group B,with significant difference (P＜0.05).The number of blood glucose monitoring in group A was significantly less than that in group B,with significant difference (P＜0.05).The Glumaxand Gludifin group A was significantly less than that in group B,with significant difference(P＜0.05).ConclusionIntravenous single bolus insulin injection can improve the prognosis of nervous function in patients with intracerebral hemorrhage after operation together with stress hyperglycemia,and can reduce the maximum blood glucose and blood glucose difference after ICU.
2017 Vol. 24 (18): 38-40 [
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Comparative study of cognitive function in patients with bipolar affective disorder in remission period and their close relatives and normal population
XU De-chun;ZHANG Cheng-cheng
ObjectiveTo compare the cognitive function between patients with bipolar affective disorder in remission period and its close relatives and normal population.Methods50 cases of bipolar affective disorder typeⅠpatients in remission period in our hospital from January 2015 to June 2016 were selected as the study group 1,50 cases of bipolar affective disorder typeⅡpatients in remission period were selected as the study group 2,50 cases healthy close relatives from two study groups were selected as the relatives group and 50 normal subjects were selected as the control group.All the subjects were assessed respectively by the digit symbol,trail making test A(TMT-A)time,trail making test B (TMT-B)time,digital breadth (forward,backward,total score)and Wisconsin card sorting test (WCST),and the attention,memory and executive function of each group were compared.ResultsThe TMT-A time,TMT-B time and digital breadth (forward)of the study group 1 and the study group 2 were higher than those in the relatives group and the control group,with significant difference (P＜0.05).The TMT-A time and TMT-B time of the study group 1 were longer than those of the study group 2,with significant difference(P＜0.05).The digital breadth(backward)and the total digital breadth score of the study group 1 and the study group 2 were significantly lower than those in the relatives group and the control group,with significant difference(P＜0.05).The number of digital symbols in the control group was significantly higher than that in the other three groups,with significant difference (P＜0.05).The non-persistent error number,error responses of WSCT in the study group 1,thestudy group 2 and the relatives group were significantly higher than that in the control group,with significant difference(P＜0.05).The non-persistent error number,error responses of WSCT in the study group 1 and the relatives group were significantly higher than that in the study group 2,with significant difference (P＜0.05).There was significant difference in the complete classification number,non-maintaining complete classification number and the number of responses required to complete the first classification and the number of total responses between the study group 1,the relatives group and the study group 2,the control group (P＜0.05).ConclusionThere are many cognitive impairment in patients with typeⅠand typeⅡin remission stage and their close relatives,and the damage of executive power in typeⅠpatients is more obvious,the damage of attention in typeⅡpatients is more obvious than that in typeⅠpatients.
2017 Vol. 24 (18): 41-43转46 [
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Comparison of the effect of ureteroscopic pneumatic lithotripsy in the treatment of lower ureteral calculi under local and epidural anesthesia
LI Zhi-wei;ZHAO Guo-chi;LAI You-ping;XING Shou-ping
ObjectiveTo explore the effect of ureteroscopic pneumatic lithotripsy in the treatment of lower ureteral calculi under local and epidural anesthesia.MethodsAltogether 150 patients with lower ureteral calculi who were hospitalized in our hospital from March 2014 to February 2015 were involved as the object of this research,all patients were treated with ureteroscopic pneumatic lithotripsy and averagely divided into the observation group and the control group according to the simple randomization,with 75 patients in each group.The observation group was administered with local anesthesia,the control group was administered with epidural anesthesia.The hospitalization time,hospitalization expenses and the incidence rate of complications of the two groups were observed.ResultsThere was no significant difference in the operation time between the two groups(P＞0.05).The hospitalization time of the observation group was shorter than that of the control group,and the hospitalization expense of the observation group was less than that of the control group,with significant difference (P＜0.05).There was no significant difference in the operation success rate,the stone clearance rate and the incidence rate of complication between the two groups (P＞0.05).ConclusionThe effect of ureteroscopic pneumatic lithotripsy in the treatment of lower ureteral calculi under local anesthesia is significant,the hospitalization time is short,and it is an effective and economical new clinical technology,which is worthy of promotion and popularizing.
2017 Vol. 24 (18): 44-46 [
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Influence of combined spinal-epidural anesthesia and tracheal intubation general anesthesia on neonatal breathing in cesarean section surgery
HUANG Min;OU Shao-mei;DENG Mei-fang
ObjectiveTo analyze the influence of combined spinal-epidural anesthesia and tracheal intubation general anesthesia on neonatal breathing in cesarean section surgery.Methods90 cases of cesarean section surgery in our hospital from September 2015 to January 2017 were selected and randomly divided into the combined spinal-epidural anesthesia group and the general anesthesia group,45 cases in each group.The general anesthesia group was given tracheal intubation general anesthesia.the combined spinal-epidural anesthesia group was given combined spinal-epidural anesthesia.The ratio of neonatal chest compression,assisted respiration and drug resuscitation,the time of cesarean section,the time from skin incision to the time of taking out the fetus,and the first breath time of the newborn,the score of neonatal Apgar at 1,5,10 min after birth,neonatal umbilical artery blood gas analysis index were compared between the two groups.ResultsThere was no significant difference in the ratio of chest compression,assisted respiration and drug resuscitation in neonates between the two groups (P＞0.05).There was no significant difference in the neonatal Apgar scores at 5 and 10 min after birth between the two groups(P＞0.05).The neonatal Apgar score at 1 min after birth in the combined spinal-epidural anesthesia group was higher than that in the general anesthesia group,with significant difference(P＜0.05).There was no significant difference in the time of cesarean section,the time from skin incision to the time of taking out the fetus between the two groups(P＞0.05).The first breath time of the newborn in the combined spinalepidural anesthesia group was shorter than that in the general anesthesia group,with significant difference(P＜0.05).There was no significant difference in the neonatal umbilical artery blood gas analysis index between the two groups(P＞0.05).ConclusionThe influence of combined spinal-epidural anesthesia and tracheal intubation general anesthesia on the neonatal respiratory in cesarean section surgery is different,the influence of combined spinal-epidural anesthesia on neonatal breathing in cesarean section surgery is less,which can shorten the first breathing time and improve the birth immediate children with Apgar score,reduce drug recovery and assisted breathing applications,it is worth promoting.
2017 Vol. 24 (18): 47-49 [
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Analgesic effect of Sufentanil combined with Remifentanil on esophageal cancer surgery and its effect on stress response
ZHANG Bo-qing;YANG Li;XIAO qing-hua;QIU Wei-dong
ObjectiveTo investigate the analgesic effect of Sufentanil combined with Remifentanil in esophageal cancer surgery and its effect on stress response.Methods90 patients with esophageal cancer surgery from January 2015 to December 2016,were selected and divided into 3 groups,30 patients were given Sufentanil anesthesia induction(study group 1),30 patients were given Remifentanil anesthesia induction(study group 2),30 patients were given Sufentanil and Remifentanil anesthesia (study group 3).HR,SBP,DBP,NE,E,Cor and VAS score,extubation time,cases of postoperative analgesic requirements in different time of the three groups were compared.ResultsHR,SBP and DBP of the three groups in T2were significantly decreased compared with T1(P<0.05).HR,SBP and DBP in T3,T5and T7in study group 2 were significantly higher than those in the other two groups(P<0.05).The plasma NE concentration in T4,T6and T8of study group 2 was significantly higher than that of the other two groups(P<0.05).The postoperative extubation time of study group 2 and 3 was significantly shorter than that of study group 1(P<0.05).There were significant differences in the VAS score and the ratio of patients who required analgesia between the study group 2 and the other two groups (P<0.05).ConclusionSelection of Sufentanil and Remifentanil has good analgesic effect of anesthesia in patients with esophageal cancer surgery,and stress response is little,hemodynamic stability is high,extubation time is short.
2017 Vol. 24 (18): 50-52 [
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Influence of Tirofiban on cardiac function and hs-CRP in acute ST-segment elevation myocardial infarction patients after emergency percutaneous coronary intervention
LIANG Jian-wen;LIANG Lun-chang;CHEN Wei-quan
ObjectiveTo explore the influence of Tirofiban on cardiac function and inflammatory factors in patients with acute ST-segment elevation myocardial infarction (ASTEMI)after emergency percutaneous coronary intervention(PCI).MethodsA total of 80 cases of patients diagnosed ASTEMI and treated with PCI surgery from October 2013 to December 2016 in our hospital were selected and divided into the control group and the observation group according to random number table method,40 cases in each group.Clopidogrel and Aspirin were used for anti-platelet aggregation and Low-Molecular-Weight Heparin was used for anticoagulation in the control group.Tirofiban was used through coronary injection during the PCI surgery in the observation group.The levels of left ventricular ejection fraction(LVEF),B type natriuretic peptide(BNP),high sensitive C reactive protein(hs-CRP)and tumor necrosis factor(TNF-α)before and after the treatment in the two groups were observed,the blood flow grade of myocardial perfusion and adverse reactions were comparedbetween the two groups.ResultsThe levels of hs-CRP and TNF-α after treatment in the observation group was lower than that in the control group,with significant difference(P＜0.05).The level of LVEF after treatment in the observation group was higher than that in the control group after treatment,the level of BNP after treatment in the observation group was lower than that of the control grouper treatment,with significant difference (P＜0.05).There was no significant difference between the two groups in the classification of myocardial perfusion and blood flow,the incidence of bleeding events(P＞0.05).ConclusionTirofiban has a significant effect in improving the cardiac function and inflammatory response after emergency PCI for ASTEMI,which is safe and reliable and worth promoting.
2017 Vol. 24 (18): 53-56 [
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Application study of magnetic resonance diffusion weighted imaging and chemical shift imaging in differential diagnosis of benign and malignant vertebral fractures
ZHANG Xun-ping;ZHANG Mei-shun;ZHAI Jin-tian;ZOU Jia-ji
ObjectiveTo investigate the value of magnetic resonance diffusion weighted imaging and chemical shift imaging in differential diagnosis of benign and malignant vertebral fractures.Methods40 patients with benign and malignant vertebral fractures in our hospital from January 2016 to January 2017 were selected,and magnetic resonance diffusion weighted imaging and chemical shift imaging were used for diagnosis.The diagnostic coincidence rate,missed diagnosis rate and misdiagnosis rate were compared between the two methods.ResultsThe diagnostic coincidence rate of magnetic resonance diffusion weighted imaging was 90.00%,which was higher than 50.00%of chemical shift imaging,with significant difference (P＜0.05).The missed diagnosis rate and misdiagnosis rate of magnetic resonance diffusion weighted imaging was lower than that of magnetic resonance chemical shift imaging,with significant difference(P＜0.05).ConclusionThe diagnosis of benign and malignant vertebral fractures with diffusion weighted imaging has higher diagnostic accuracy and can reduce the rate of clinical misdiagnosis and missed diagnosis,which is worth studying.
2017 Vol. 24 (18): 57-59 [
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Application value of prenatal ultrasound in the diagnosis of placenta previa and implantation
LUO Xiao;YANG Cheng-ying;ZHENG Ying-kai;LIN Wen-wu;WEI Li-hua
ObjectiveTo explore the application value of prenatal ultrasound in the diagnosis of placenta previa and implantation.Methods60 patients with suspected placenta accreta were selected during antenatel examinations in our hospital from March to December in 2016,all of them were performed with antenatal color Doppler ultrasonography.The imaging features of the patients were analyzed for judgment of placenta accrete or not.Based on the results of pathological examination,the accuracy of ultrasound diagnosis was calculated.ResultsAmong these participants,the detection rate of placenta previa and implantation was 13.33%by color Doppler ultrasonography,and the detection rate by surgical pathology was 15.00%,there was no significant difference(P＞0.05).The accuracy rate of color Doppler ultrasonography was 88.89%.ConclusionPrenatal ultrasound diagnosis is characterized by simple operation,reproducibility,and high accuracy,and is an effective way to diagnose the placenta previa and implantation,which is of great extensive application value.
2017 Vol. 24 (18): 60-62 [
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CT features of renal angiomyolipoma with minimal fat
HUANG Zhong-qing ZHOU Xin-wei▲ZHANG De-qing;LU Xian-zhong;MENG Zhi-hua;DENG Yu-yun;CHEN Zhen-song;FANG Xian-lai
ObjectiveTo explore the CT characteristics of renal angiomyolipomas with minimal fat,thereby improving the understanding of this syndrome.MethodsThe CT findings of 13 cases of renal angiomyolipoma with minimal fat confirmed by surgery and pathology in our hospital from March 2011 to October 2016 were analyzed retrospectively.ResultsIn this group of cases,9 lesions were nearly-circular or round;9 lesions showed exophytic growth;8 lesions showed the"V"angle sign with the junction of renal parenchyma junction;"Cup"change was detected with 2 lesions;slightly high density was found with 8 lesions;homogeneous enhancement was found with 8 lesions at renal parenchymal phase;6 lesions showed obvious enhancement,3 lesions showed moderate enhancement,4 lesions showed mild enhancement.Dynamic enhancement in 9 lesions was prolonged.ConclusionCT manifestations of renal angiomyolipomas with minimal fat have certain features.Aside from CT density,morphological characteristics,growth pattern,enhancement level and enhancement pattern of the symptom are helpful for the diagnosis.
2017 Vol. 24 (18): 63-65 [
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Effect comparison of the transvaginal three-dimensional ultrasoundguided vaginal surgery and hysteroscopy combined with laparoscopy in the treatment of incisional scar diverticulum after cesarean section
HUANG Hui-qin;LEI Juan-ying;WANG Ping
ObjectiveTo compare the clinical effect of transvaginal three-dimensional ultrasound-guided vaginal surgery and hysteroscopy combined with laparoscopy in the treatment of incisional scar diverticulum after cesarean sec tion,so as to provide reference for clinical treatment.MethodsAltogether 46 cases of patients who were treated with repair of incisional scar diverticulum after cesarean section from June 2012 to December 2016 in People′s Hospital of Baiyun District were selected as the object of this research and divided into transvaginal three-dimensional ultrasound-guided vaginal surgery group(38 cases)and hysteroscopy and laparoscopy combination group(8 cases)according to the different surgical methods.The treatment effect was compared between the two groups.ResultsThe operation time and length of hospital stay of transvaginal three-dimensional ultrasound-guided vaginal surgery group were shorter than those of hysteroscopy and laparoscopy combination group,intraoperative blood loss and treatment costs of transvaginal three-dimensional ultrasound-guided vaginal surgery group were less than those of hysteroscopy and laparoscopy combination group,with significant difference(P＜0.05).The total effective rate of the two groups was not statistically significant(P＞0.05).ConclusionCombination of transvaginal three-dimensional ultrasound-guided vaginal surgery and hysteroscopy plus laparoscopic surgery can achieve good results in treatment of incisional scar diverticulum after cesarean section,combination of transvaginal three-dimensional ultrasound-guided vaginal surgery is more worthy of promotion for the areas with poor clinical medical conditions,relatively weak technical strength and low living standards.
2017 Vol. 24 (18): 66-68转71 [
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Clinical application of CT,X-ray and MRI in the diagnosis of sacroiliac joint disease of ankylosing spondylitis
ZHANG Peng-qi;LYU Yong-bin
ObjectiveTo explore the clinical application value of CT,X-ray and MRI in the diagnosis of sacroiliac joint disease in ankylosing spondylitis.MethodsFrom December 2014 to March 2017,81 cases of sacroiliac joint disease in ankylosing spondylitis in our hospital were selected and randomly divided into group A,group B,group C,27 cases in each group.Group A was examined by X-ray examination,group B was given MRI imaging,group C was given 64-slice spiral CT scan.The diagnostic effect and image quality of the three methods were observed.ResultsThe detection rate of clinical features of group B and group C was significantly higher than that of group A,with significant difference (P＜0.05).There were no significant differences in the detection rates of clinical features between group B and group C (P＞0.05).The diagnostic accuracy of classification of group B and group C was higher than that in group A,with significant difference (P＜0.05).ConclusionThe accuracy of CT and MRI examination in patients with ankylosing spondylitis and sacroiliac joint disease is significantly higher than that of X-ray examination,the main clinical features were joint swelling,osteoarthritis,osteoporosis and articular surface Erosion and so on,and the inspection operation is simple and convenient,with a certain accuracy and feasibility,it is worthy of clinical promotion and application.
2017 Vol. 24 (18): 69-71 [
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154
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Pharmacoeconomic comparative study of XELOX regimen and FOLFOX regimen in the treatment of advanced colon cancer
WANG Jing-yan;HU Ni;WU Yong-wen;LE Liang
ObjectiveTo study the pharmacoeconomics of XELOX regimen and FOLFOX regimen in the treatment of advanced colon cancer patients.MethodsFrom January 2015 to October 2016,120 patients with advanced colon cancer were studied in our hospital.They were randomly divided into group A and group B.Each group of 60 patients.Patients in group A were treated with XELOX regimen,and group B was treated with XELOX regimen.The curative effect,hospitalization time and cost of the two groups were evaluated.ResultsThe total effective rate of group A was 63.33%,B group was 66.67%,and there was no significant difference between the two groups(P>0.05).The disease control rate of the group A was 86.67%,group B was 90．00%,had no significant difference between the two groups(P>0.05);group A and group B respectively of weekly hospitalization expenses was （9670.0±381.4） and （11059.0±350.6）yuan,there was significant difference between two groups （P<0.05）.The hospital stays in the group A and B was（56.3±2.5） d and （88.4±3.8） d,the difference between the two groups was statistically significant （P<0.05）.ConclusionThe curative effect has no significant difference between the XELOX regimen and the FOLFOX regimen.The hospitalization expenses of the former is lower.The days of hospitalization in the former regimen is shorter,and the gastrointestinal reaction is lighter and safer.
2017 Vol. 24 (18): 72-74 [
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191
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Effect of high dose Budesonide combined with Terbutaline treating acute attack of asthma and its influence on pulmonary function and safety
WEN Xiang-fei;YUAN Ming;LIAO Xiao-dong
ObjectiveTo investigate the effect of high dose Budesonide combined with Terbutaline treating acute attack of asthma and its influence on pulmonary function and safety.Methods62 cases with acute attack of asthma treated in our hospital from April 2015 to March 2017 were selected as the research object,and they were randomly divided into the observation group and control group,and each group had 31 cases.The control group was given conventional high dose Budesonide inhalation treatment,and the observation group was treated with high dose Budesonide combined with Terbutaline atomization.The lung function indexes(forced vital capacity,forced expiratory volume in the first second and percentage of predicted value),adverse reactions and the total effective rate were compared between the two groups.Results The disappeared time of clinical symptoms in the observation group was significantly shorter than that of the control group,the difference was statistically significant(P<0.05);the patients in the observation group at the end of the first second forced vital capacity,forced expiratory volume and percentage of predicted values were compared with before treatment had improved,but the patients in the observation group was significantly better than the control group,the difference was statistically significant(P<0.05).There was no adverse reaction during treatment and after treatment in the two groups.The total effective rate of the observation group was significantly higher than the control group,and the difference was statistically significant(P<0.05).ConclusionHigh dose Budesonide combined with Terbutaline treating acute attack of asthma can significantly improve the pulmonary function of patients,reduce adverse reactions,improve the relationship between doctors and patients,and ultimately improve the therapeutic effect.
2017 Vol. 24 (18): 75-77 [
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Analysis of hematological adverse reactionscaused by Linezolidand drug safety
Jibieke Nuerzihan;MA Jia-ping
ObjectiveTo investigate the characteristics of hematological adverse reactions caused by linezolid and analyze the safety of drug.MethodsClinical data of 220 patients hospitalized in our hospital from January 2015 to January 2016 were retrospectively reviewed.220 patients were treated with Linezolid during hospitalization.The adverse reactions of patients with Linezolid were observed,the adverse reactions of blood system and the drug withdrawal were analyzed,and the relationship between the incidence of adverse reactions and the duration of medication was explored.ResultsIn 220 patients,adverse reactions occurred in 72 patients,and it resulted in discontinuation of the drug in 13 patients;there were no adverse reactions in 148 patients.The incidence of adverse reactionof Linezolid was higher in men than in women.Elderly patients over the age of 70 tended to suffer from Linezolid adverse reactions.The clinical manifestation of the patients with blood adverse reaction was the inhibition of blood system,the obvious decrease of platelets,the obvious decrease of hemoglobin and the obvious decrease of neutrophils,and the inhibition of blood system was the main clinical manifestation of blood adverse reaction.The longer the treatment time,the higher the incidence of adverse reactions.ConclusionLinezolid treatment can cause hematological adverse reactions in clinic,medical personnel should pay attention in the treatment of patients in treatment and nursingof them.For patients with adverse reaction,medical staff should be the right remedy to ensure that patients get an effective and safe treatment.
2017 Vol. 24 (18): 78-80 [
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169
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Clinical effect of Polyene Phosphatidylcholine combined with 0rnithine Aspartate in the treatment of hepatic encephalopathy
LIN Li
ObjectiveTo investigate the clinical effect of Polyene Phosphatidylcholine combined with 0rnithine Aspartate in the treatment of hepatic encephalopathy.Methods100 patients with hepatic encephalopathy treated in our hospital from November 2013 to November 2016 were selected and they were randomly divided into the experimental group(49 cases)and control group(51 cases).Patients in the experimental groupwere given Polyene Phosphatidylcholine combined with Ornithine Aspartate for treatmenton the basis of routine comprehensive treatment and the control group was given valley ammonia acid sodium(potassium)combined with Glycyrrhizic Acidon the basis of routine comprehensive treatment.The clinical curative effect after treatment was compared.ResultsTBil,ALT,AST in the experimental group was(33.3±10.4)μmol/L,(100.2±22.1)IU/L and(110.3±23.5)IU/L respectively,and they were superior to those in the control group,with statistical significances(P<0.05).The total effective rate of the treatment group was 97.96%,which was higher than that of the control group(86.27%),and there was a statistical significance(P<0.05).ConclusionOn the basis of conventional treatment,Polyene Phosphatidylcholine combined with Ornithine Aspartate in the treatment of hepatic encephalopathy has a better effect,and this therapy is worth exploring.
2017 Vol. 24 (18): 81-83 [
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146
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Clinical efficacy of Levoflox acin combined with Azithromycin in the treatment of refractory respiratory tract Infections in elderly patients
HUANG Hui;WAN Lin;ZOU Huai-yu;WAN Min-na;WAN Jie-hua
ObjectiveTo investigate the efficacy of Levofloxacin combined with Azithromycin in the treatment of refractory respiratory tract infections(RTI)in elderly patients.MethodsAltogether 130 cases of elderly patients with refractory RTI who were treated in our hospital from May 2015 to December 2016 were randomly selected as the object of this research and randomly divided into observation group(n=65)and control group(n=65);control group were treated with Levofloxacin;observation group were treated with combination of Levofloxacin and Azithromycin;the total effective rate,remission time of clinical symptoms and incidence of adverse reaction of two groups were compared.ResultsThe total effective rate of observation group was 98.46%,higher than that of control group(84.62%)(P<0.05);the incidence of adverse reaction of observation group was 6.15%,slightly higher than that of control group(4.62%)(P>0.05);the disappearance time of cough,fever and pulmonary rales of observation group was shorter than that of control group,P<0.05;IL-8,CRPand TNF-α levels of observation group in the 7 th treatment day were lower than those of control group;and the IL-10 level of observation group was higher than that of control group,P<0.05.ConclusionApplication of combination of Levofloxacin and Azithromycin is effective and safe in the treatment of refractory respiratory tract infections in elderly patients,which is worth popularizing in clinical practice.
2017 Vol. 24 (18): 84-86转89 [
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150
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Effect of Ceftriaxone Sodium combined with Tanreqing Injection in treating bronchial pneumonia in children
YANG Ji-hong
ObjectiveTo observe the clinical effect of Ceftriaxone Sodium combined with Tanreqing Injection in treating bronchial pneumonia in children.Methods120 children with of bronchial pneumonia treated in inpatient department of our hospital from March 2014 to December 2015 were selected and they were randomly divided into the two groups and each group had 60 cases.The observation group was treated with Ceftriaxone Sodium combined with Tanreqing Injection,while the control group was treated with Ceftriaxone Sodium combined with Ambroxol Injection.The total effective rate,temperature recovery time,clinical symptom disappearance time,lung sign disappearance time and hospitalization time were compared between the two groups.ResultsThe total effective rate of patients in the observation group(95.00%)was significantly higher than that of the control group(76.67%)(P<0.05).Temperature recovery time[(1.61±0.36)d],clinical symptom disappearance time[(3.51±0.55)d],lung sign disappearance time[(5.32±1.25)d]and hospitalization time[(7.25±2.11)d]were shorter than those of the control group[(2.61±0.45),(4.51±1.05),(6.45±1.42),(8.56±2.30)d](P<0.05).ConclusionThe effect of Ceftriaxone Sodium combined with Tanreqing Injection treating bronchial pneumonia is significant and can effectively improve the clinical manifestation of patients and shorten the course of disease.It is worthy to be popularized in clinic.
2017 Vol. 24 (18): 87-89 [
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Effect of Extract of Ginkgo Biloba Leaves Tablets on hearing in patients with nasopharyngeal carcinoma undergoing radiotherapy
CHEN Hao-ying;ZHANG Long-cheng
ObjectiveTo explore the effect of extract of Ginkgo Biloba Leaves Tablets on complications and hearing loss in nasopharyngeal carcinoma patients undergoing radiotherapy.Methods60 patients with nasopharyngeal carcinoma treated by radiotherapy were selected from December 2013 to December 2016,and they were randomly divided into the observation group and the control group,30 patients in each group.The two groups were given radiotherapy for nasopharyngeal carcinoma,while the observation group was treated with Extract of Ginkgo Biloba Leaves Tablets at the same time.The two groups were treated continuously for 3 months.The hearing loss in two groups were observed before and after radiotherapy.ResultsThe total effective rate of hearing improvement in observation group was higher than that in control group,the difference was statistically significant(P<0.05).The air conduction hearing threshold，middle ear pressure respectively in the observation group before radiotherapy were compare with those in the control group before radiotherapy,the difference was not statistically significant（P>0.05）;the air conduction hearing threshold in the observation group after radiotherapy was lower than the control group after radiotherapy,the middle ear pressure pressure in the observation group after radiotherapy was higher than the control group after radiotherapy,the difference was statistically significant(P<0.05).ConclusionExtract of Ginkgo Biloba Leaves Tablets can reduce the degree of middle ear injury during nasopharyngeal carcinoma radiotherapy,and the effect is significant.
2017 Vol. 24 (18): 90-92 [
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106
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Methodology research on microbial limit test of Wuqi Shujin Tongluo Tablets
CHEN Zhen-yao;XIE Kai-biao;YAO Wei-sheng
ObjectiveTo establish a microbial limit test method of Wuqi Shujin Tongluo tablets.MethodsMethodology research on microbial limit test of Wuqi Shujin Tongluo tablets was conducted according to the"1105,1106,1107"of Chinese Pharmacopoeia 2015 edition with the fourth part.ResultsThe total number of aerobic bacteria could be tested by plate dilution method and membrane filtration method,the total number of fungus and yeasts could be tested by the plate routine method,and the recovery was between 0.5 and 2,Escherichia coli,Salmonella,Bile salt resistant Gram-negative bacteria could be detected through control bacteria by direct inoculation method.ConclusionThe total number of aerobic bacteria can be tested by plate dilution method,the total number of fungus and yeasts can be tested by plate routine method,and the control bacteria can be tested by direct inoculation method,the methods used are feasible,and easier to operate,which are suitable for the microbial limit test of Wuqi Shujin Tongluo tablets.
2017 Vol. 24 (18): 93-96 [
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120
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Effect observation of Fructus Evodiae acupoint sticking combined with auricular point pressing in treating insomnia
LIANG Hui-qiong;ZHUANG Chun;ZHU Miao-fen
ObjectiveTo observe the treatment effect of Fructus Evodiae acupoint sticking combined with auricular plaster therapy on patients with insomnia.MethodsFrom August 2016 to April 2017,40 cases of insomnia patients in Department of Encephalopathy of our Hospital were selected and randomly divided into control group and observation group,with 20 cases in each group.The control group was given Estazolam for treatment,and the observation group was given Fructus Evodiae Yongquan acupoint sticking combined with auricular point compression.The Pittsburgh sleep quality index scale was used to evaluated the quality of sleep before and after treatment;treatment effect and adverse reactions during treatment of patients in the two groups were observed.ResultsAfter treatment,Pittsburgh sleep quality index of the observation group was lower than that of the control group,the difference was statistically significant(P<0.05);the effective rate of the observation group was 90%,was higher than that of the control group higher than 75%of the control group,the difference was statistically significant(P<0.05);there was 1 case of adverse reactions in the observation group,and 10 cases in the control group during the treatment,there was statistically significant difference in the incidence of adverse reactions(P<0.05).ConclusionThe application of Fructus Evodiae acupoint sticking combined with auricular point pressing for the treatment of insomnia has a definite effect,it is worthy of clinical application.
2017 Vol. 24 (18): 97-99转105 [
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131
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Effect observation of Tongduhuoluo lotion in the treatment of lumbar disc herniation
WANG Zhi-juan;GUO Yong
ObjectiveTo investigate the effect of Tongduhuoluo lotion in the treatment of lumbar disc herniation.Methods112 patients with lumbar disc herniation treated in our hospital from January 2012 to December 2013 were selected and they were randomly divided into the control group and treatment group,and each group had 56 cases.Patients in the control group were treated with conventional traction and manipulation,while the treatment group was treated with external application of Tongduhuoluo lotion on the basis of the control group.The therapeutic effect between the two groups was compared.ResultsAfter treatment,the symptoms and signs score and the daily activity score of the two groups were decreased significantly,and the symptoms and signs score and daily activity score of the treatment group after treatment were lower than those of the control group (P<0.01).The total effective rate of the treatment group was 94.64%,and that was 78.57%in the control group,the difference between the two groups was statistically significant(P<0.01).Conclusion Tongduhuoluo lotion in the treatment of lumbar disc herniation has a obvious effect.
2017 Vol. 24 (18): 100-102 [
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Clinical effect and safety of medicinal vesiculation in the treatment of allergic rhinitis
LIU Hui-zhen;ZHENG Pei-yin;XIANG Li
ObjectiveTo investigate the clinical effect and safety of medicinal vesiculation in the treatment of allergic rhinitis.Methods240 patients with allergic rhinitis treated in our Community Health Service Center and diagnosed by department of ENT from February 2014 to February 2016 were selected and they were divided into the two groups by drawing lots,and there were 120 cases in each group.The control group was treated with Budesonide Nasal Spray,and the observation group was treated with medicinal vesiculation.The score of symptoms and signs before and after treatment,clinical efficacy and safety were compared between the two groups.ResultsAfter treatment,the total effective rate of the observation group was significantly higher than that of the control group(83.33%vs.40.83%),and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).ConclusionMoxibustion in the canicular days and coldest days of winter in the treatment of allergic rhinitis has a significant clinical efficacy,and it is worthy of clinical promotion.
2017 Vol. 24 (18): 103-105 [
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135
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Clinical effect of combined treatment of traditional Chinese medicine and western medicine treating chronic skin ulcer
ZHOU Jun
ObjectiveTo observe the clinical curative effect of combination therapy of traditional Chinese and western medicine treatment of chronic skin ulcer.Methods160 cases with chronic skin ulcer treated in our outpatient ofour department from August 2014 to August 2016 were selected and they were randomly divided into the control group and treatment group and each group had 80 cases.All patients were given conventional western medicine treatment.On this basis,the treatment group was given traditional Chinese medicine decoction additionally.The skin wound healing rate and symptom integral would be observed after treatment.Then the curative effect would be evaluated.ResultsAfter treat ment,the cure rate of treatment group was 38.75%,and total effective rate was 95.00%,which was significantly higher than the control group(20.00%,72.25%).The average wound healing rate significantly higher than the treatment group was(61.32±12.41)%,which was significantly higher than the control group[(48.95±8.19)%].The average wound healing time of healed patients was(18.65±3.14)days in the treatment group,which was significantly shorter than that of the control group[(27.32±5.63)d].Compared with the control group[(2.93±0.46)points],the patients′average of TCM symptom score of treatment group[(1.04±0.08)points]was decreased obviously.The recurrence rate of treatment group from cure patients in half a year was 6.75%,which was significantly lower than the control group(21.25%).All the differences were statistically significant(P<0.05).ConclusionThe combination therapy of Chinese and western medicine is applied to treat chronic skin ulcer,which can effectively improve the cure rate and relieve the patients'clinical symptoms.It is an effective method for clinical treatment.
2017 Vol. 24 (18): 106-108 [
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Value of the joint detection of serum cystatin C and retinol binding protcin in the diagnosis of early renal damage for diabetes patients
LAI Xin
ObjectiveTo explore the clinical value of the joint detection of serum cystatin C(Cys C)and urinary retinol binding protcin(RBP)in the diagnosis of early renal damage for diabetic patients.Methods60 diabetic patients with early renal damage treated in our hospital from June 2015 and June 2016 were selected as the observation group,and they all underwent joint detection of serum Cys C and urinary RBP.Simultaneously,60 cases of the healthy people undergoing medical examination in our hospital were selected as the control group,and they all underwent joint detection of serum Cys C and urinary RBP.A comarison was made in serum Cys C and urinary RBP between the two groups to analyze the clinical value of in the diagnosis of early renal damage for diabetic patients.ResultsThe levels of serum Cys C and urinary RBP test results of the observation group were significantly higher than those of the control group,and the difference was statistically significant(P＜0.05).The positive rate of joint detection of serum Cys C and urinary RBP in the diagnosis of early renal injury in diabetes was significantly higher than that in single serum CysC test and urine RBP test,with significant difference(P＜0.05).ConclusionThe joint detection of serum Cys C and urinary RBP can provide reliable basis for the diagnosis of early renal damage for diabetic patients,and it is worthy of clinical promotion and application.
2017 Vol. 24 (18): 109-110转120 [
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147
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Comparison of the accuracy of electrochemiluminescence immunoassay and enzyme-linked immunosorbent assay in the detection of hepatitis B virus markers
SHI Zhen-gang
ObjectiveTo analyze and compare the accuracy of electrochemiluminescence immunoassay(ECLIA)and enzyme-linked immunosorbent assay(ELISA)in the detection of hepatitis B virus(HBV)markers.Methods160 patients with HBV treated in our hospital from January 2015 and January 2017 were selected as research targets,and were randomly divided into the observation group(n=80)and the control group(n=80).The observation group was given ECLIA and the control group was given ELISA,the positive rates of HBV markers were compared between the two groups.Then in the observation group,HBsAg/Ab and/or HBeAg/Ab double positive patients were selected and detected by ELISA method,and the results were observed.ResultsThe positive rates of HBsAg,HBsAb,HBeAg and HBeAb in the observation group were 100.0%,52.5%,76.3%and 78.8%respectively,which was higher than 92.5%,45.2%,52.5%,50.0%in the control group,with significant difference(P＜0.05).The number of patients with the s and/or e system double positive detection results by the method of ECLIA were 76 cases,but the number by the method of ELISA were comparatively 9 cases.ConclusionCompared with ELISA,ECLIA is more accurate in the detection of HBV infection,therefore,it is worthy of wide clinical promotion and application.
2017 Vol. 24 (18): 111-113 [
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Correlation study between coagulation function and arterial blood gas indexes in acute exacerbation of chronic obstructive pulmonary disease
JIANG Ling-zhi;XU Dan-yuan;YANG Zhi-xiong
ObjectiveTo explore the correlation between coagulation function and arterial blood gas indexes in acute exacerbation of chronic obstructive pulmonary disease.Methods56 patients with acute exacerbation of chronic obstruc tive pulmonary disease admitted to our hospital from June 2013 to August 2015 were selected as group A,after treatment were selected as group B,on the other hand,56 healthy persons for physical examination in our hospital were selected as group C.The level of fibrinogen(Fbg),D-two dimer(D-D),prothrombin time(PT),activated partial thromboplastin time(APTT),thrombin time(TT),oxygen partial pressure(PaO2),partial pressure of carbon dioxide(PaCO2)of all the research object were determined,the correlation between blood coagulation function index and arterial blood gas indexes was analyzed.ResultsThere was no significant difference in the level of PT,APTT and TT between the three groups(P＞0.05);the levels of D-D,Fbg,PaCO2in group A was higher than that in group B and group C,the difference was statistically significant(P＜0.05),and the PaO2level was lower than that of B and C group,the difference was statistically significant(P＜0.05).There are negative correlation between D-D and PaO2,the difference was statistically significant(r=-0.232,P＜0.05);D-D was positively correlated with PaCO2,the difference was statistically significant(r=0.284,P＜0.05);Fbg was positively correlated with PaCO2,the difference was statistically significant(r=0.437,P＜0.05);Fbg was negatively correlated with PaO2,with significant difference(r=-0.465,P＜0.05).ConclusionThere is a high coagulation state in acute exacerbation of chronic obstructive pulmonary disease,and the monitoring of D-D and Fbg indexes can provide a certain data base for the improvement of prognosis.
2017 Vol. 24 (18): 114-117 [
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Clinical value of morphological examination of bone marrow cells in the identification of refractory anemia and megaloblastic anemia
YUAN Xiao-feng
ObjectiveTo compare and analyze the clinical value of morphological examination of bone marrow cells in the identification of refractory anemia and megaloblastic anemia.Methods64 anemia patients treated in our hospital from October 2013 to October 2016 were selected as observation objects,and 32 cases were refractory anemia,32 cases were megaloblastic anemia.Participants in the two groups were all provided with the clinical test of morphological examination of bone marrow cells,and test results were analyzed and compared.ResultsIn the refractory anemia group,the positivity rate of PAS was 71.88%,the proportion rates of erythroid pathosis,granulocytic pathosis,and lymphoid megakaryocytes was 65.63%,75.00%,and 100.00%;while in the megaloblastic anemia group,they were 3.13%,15.63%,6.25%,and 0.00%respectively,which were displayed great differences after comparisons(P＜0.05).In the refractory anemia group,the diameters of megaloblastic pronormoblast and normoblast were(18.64±4.23)μm and(17.84±2.84)μm,which was shorter than(23.84±6.49)μm and(20.87±4.69)μm in the megaloblastic anemia group,with significant difference(P＜0.05).Meanwhile,the red cell distribution width in the megaloblastic anemia group was(16.35±3.47)%,which was much lower than(28.94±7.22)%in the refractory anemia group,with significant difference(P＜0.05).There was no significant difference in the level of hemoglobin,platelet and white blood cells between the two groups(P＞0.05).ConclusionThe clinical value of morphological examination of bone marrow cells in refractory anemia and megaloblastic anemia is substantial,and is worthy of further promotion.
2017 Vol. 24 (18): 118-120 [
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Value analysis of six-item sex hormone test of adult women in the diagnosis of the female patients with infertility
LI Han-huang;WU Zhi-jun
ObjectiveTo investigate the diagnostic value of six-item sex hormone test of adult women in female patients with infertility.MethodsA total of 80 women with infertility from January 2016 to January 2017 in our hosptial were selected as the observation group,another 80 healthy adult women were selected as the control group during the same period.The six items of sex hormones were compared between the two groups.ResultsAccording to the analysis of overall levels,there was no significant differences in the level of FSH between the two groups(P＞0.05).The levels of LH,PRL and TESTO in the observation group was higher than that in the control group,and the levels of E2and P in the observation group was lower than that of the control group,with significant difference(P＜0.05).According to the analysis of stage levels,the levels of LH,FSH,PRL,TESTO and P in the follicular phase in the observation group was higher than that in the control group,and the level of E2in the follicular phase in the observation group was lower than that in the control group,with significant difference(P＜0.05).The levels of LH,E2,TESTO and P in the ovulation period in the observation group was lower than that in the control group,with significant difference(P＜0.05).The levels of LH and PRL in the luteal phase in the observation group was higher than that in the control group,and the levels of TESTO and P in the luteal phase of the observation group was lower than that of the control group,with significant difference(P＜0.05).ConclusionFemale sex hormone secretion directly affects the pregnancy status.Six-item sex hormone test in the diagnosis of infertility has a certain clinical significance.
2017 Vol. 24 (18): 121-123 [
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Application of hospital failure mode and effect analysis in prevention of urinary catheter related urinary tract infection in elderly patients
WANG Dong-ping;YANG Zhi－hua;QIU Chun－xia;CHEN Wei-qiong;LIAO Guo-xia;DAI Hai－yan;ZHENG Li-ling;WANG Xu－lan
ObjectiveTo explore the application of hospital failure mode and effect analysis(HFMEA)in the prevention of catheter associated urinary tract infection(CAUTI)in elderly patients.Methods182 cases of indwelling catheter from April 2016 to June 2017 in our hospital were selected and divided into HFMEA management group (observation group)and traditional nursing group(control group),91 cases in each group,routine indwelling catheter nursing mode was used in the control group,HFMEA model was used in observation group.The high risk factor(RPN)value and the incidence of CAUTI,nursing satisfaction score were compared between two groups of patients.ResultsCompared with the control group,the RPN values of the patients in the observation group were all reduced,CAUTI in the observation group was lower,the nursing satisfaction scores were higher than those in the control group after observation group patients discharge,the difference was statistically significant(P<0.05).ConclusionHFMEA of medical treatment can reduce CAUTI and improve the nursing satisfactioninthemanagementof urinary catheter associated CAUTI in elderly patients.
2017 Vol. 24 (18): 124-126 [
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Study on defects and countermeasures of cleaning quality of disinfection and supply room
CEN Mei-zhen
ObjectiveTo analyze equipment cleaning quality defects in the disinfection supply room,and to explore related intervention measures.MethodsFrom January 2014 to January 2015,instruments and nurses carried out routine work flow were selected as the control group,instruments and nurses from February 2015 to February 2016 with the implementation of nursing defects related countermeasures were selected as experimental group.The disinfection supply room equipment cleaning quality and satisfaction with the department were compared between the two groups.ResultsThe equipment cleaning quality defects of the control group accounted 20.69%,the apparatus cleaning quality defects of the experimental group accounted 79.31%,the experimental was significantly lower than the control group (P<0.05).E-quipment cleaning quality defect types were mainly the disqualification of cleaning,unqualified packing,discharge error of items,equipment damage,cleaning not in time,loss of equipment,unqualified label and so on;the disinfection supply room equipment cleaning of the main causes of quality defects including poor sense of nurse responsibility,not strictly enforcing the rules,and the deficiency in the system of management and so on.The apparatus cleaning quality and satis faction of the experimental group were significantly higher than those of the control group(P<0.05).ConclusionIn equipment cleaning of the disinfection supply room,the strategies of defects quality can improve equipment cleaning quality and the satisfaction with the department.
2017 Vol. 24 (18): 127-130 [
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Effect of nursing safety management on nursing quality and risk events in patients undergoing abdominal surgery
YU Chun-ling
ObjectiveTo investigate the effect of nursing safety management on nursing quality and risk events in patients undergoing abdominal surgery.Methods110 patients with abdominal surgery in our hospital from August 2015 to December 2016 were selected,before the application of nursing safety management on June 2016,patients were included into control group,and after the application of nursing safety management,patients were included into observation group.The nursing quality,mental status and risk events of two groups before and after the application were compared.ResultsCompared with control group,the scores of communication skills,proficiency,responsibility,service attitude,emergency response capability,writing standardization of observation group significantly increased(P<0.05);Compared with control group,the incidence of risk events of observation group significantly decreased,and the scores of SAS,SDS in observation group were lower than those in control group(P<0.05).ConclusionNursing safety management for patients undergoing abdominal surgery can effectively increase nursing quality and reduce risk events，which is worthy of application and promotion.
2017 Vol. 24 (18): 131-133 [
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153
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134
Application effect of PDCA in intrahospital transport of patients with severe trauma
CHEN Chun-hua;ZHENG Yu-qin;CHEN Xiao-fen;TANG Hai-yan;FANG Fang
ObjectiveTo analyze the application effect of PDCA in intrahospital transport of patients with severe trauma.MethodsA total of 106 patients with severe trauma admitted between from October 2014 to September 2016 were selected and divided into observation group and control group based on random number table.Each group had 53 patients.The control group was transported in hospital by using conventional methods,while the observation group was transported in hospital by following the PDCA management concept.The incidence of adverse event,the success rate of salvation,and the time that each link of transport consumed were compared between the two groups.ResultsThe incidence of adverse event in the observation group was significantly lower than that in the control group(P<0.05);the success rate of salvation in the observation group was significantly higher than that in the control group(P<0.05);and the length of stay in emergency room,the duration of special examination,and the time of arriving at departments in the observation group was significantly shorter than that in the control group(P<0.01).ConclusionPDCA can effectively reduce the time required for intrahospital transport of patients with severe trauma,lower the incidence of adverse event,and improve the remedy results of patients.
2017 Vol. 24 (18): 134-136 [
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Application of Kirkpatrick′s assessment model to evaluate the clinical education of nursing students stage effect
ZHANG Shu-qing;XU Liu-qin;GAO Ying;ZHANG Jian-rong;CUI Xin-hao;GAO Ru
ObjectiveTo analyze the application situation of Kirkpatrick′s assessment model to evaluate the clinical education of nurse student and improve the quality of teaching.Methods76 clinical nursing interns from January to December 2016 were collected,according to Kirkpatrick′s 4 levels evaluation model,using Delphi expert enquiry for questionnaire design,drawing up 4 levels 12 items for clinical nursing internship two stages of learning situation investigation.ResultsAccording to the two stages survey,scores of different levels of the second stage were increased than the first stage,and the reaction layer,behavior layer ever was more than 10%,two stages at all levels had statistical significances(P<0.05).ConclusionKirkpatrick′s assessment model can reflect the nursing student practice the problems in the process,with the teacher by adjusting the teaching plan,effectively improve the teaching quality.
2017 Vol. 24 (18): 137-139 [
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130
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140
Application of peer education in improving the clinical practice of threeyear medical students
GANG Jun;DU Ya-qiong;ZHANG Li-rong;QIU Jian-yun
ObjectiveTo explore the application effect of peer education model in clinical practice of three-year medical students.MethodsTwenty-seven students at grade 2013 and 31 clinical interns at grade 2012 were classified into experimental group and control group respectively.They were provided with peer education and traditional teaching mode accordingly.The experimental effect was compared and analyzed by scores of after-department examinations in 5-stop type including inquiry,physical examination,auxiliary examination,writing medical records,and oral test in students from majors of internal medicine,external medicine,gynecology,pediatrics,traditional Chinese medicine,and community,and satisfaction from both teachers and patients.ResultsIn the experimental group,the total scores of all medical students from 6 majors in 5-stop type examinations were higher than that in the control group.The scores of satisfaction from both patients and teachers were higher in the experimental group than those in the control group respectively,the differences were statistically significant(P<0.05).ConclusionThe application of peer education model in the teaching practice of threeyear medical students is beneficial to improvement of mastering and intensifying the theoretical knowledge and skills as well as satisfaction both from teachers and patients.
2017 Vol. 24 (18): 140-142转146 [
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Exploration of integrated medical model in emergency medical teaching
ZHANG Yin-ming;ZHANG Wen-jie;LI Fan-wang;REN Jun;BAO Ming-zheng;XU Gang
ObjectiveTo explore the application of integrated medical model in emergency medical teaching research.MethodsTwo questionnaires(Paper A and Paper B)with the same content were issued by using self-controlled method to 93 interns who had internships in General Hospital of Yankuang Group from September 1st,2015 to May 16th,2016 before and after integrated medicine training respectively.Corresponding questions on the interns′recognition of integrated medicine,emergency medicine under integrated medicine training and the application degree of long-wire-guided gastrointestinal tube replacement were answered so as to make statistical analysis of the summarized results.ResultsAfter integrated medicine training,interns showed a marked increase in their recognition of the concept,specific content and mode application purpose of integrated medicine,and the understanding of the application degree of long-wire-guided gastrointestinal tube replacement,the differences were statistically significant(P<0.01);all the interns were well informed about the recognition of the requirements of emergency medical staff before training,and there was no statistically significant difference in their pre-and post-training recognition of the requirements of emergency medical staff(P>0.05).ConclusionIt is feasible and effective to teach medical students integrated medical content in emergency medical teaching.
2017 Vol. 24 (18): 143-146 [
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141
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The application effect of PBL method in physiological experiment teaching
HUANG Xiao-ping;DENG Bing-xiang;ZENG Hui;WEN Ju-hua;TANG Biao
ObjectiveTo explore the application model and effect of problem-based learning(PBL)in physiological experiment teaching.MethodsFrom November to December 2014,50 students from major of integration of traditional Chinese and western medicine in seven-year in grade 2013 were evenly divided into control group and experimental group,with 25 cases in each group.They were provided with traditional teaching method (LBL)and PBL for four-hour physiological experiment teaching.At the end of the course，the teaching quality and educational environment were evaluated by the test scores and the Dundee ready education environment measure(DREEM).ResultsThe corresponding scores of test and DREEM as well as total score in PBL teaching group were significantly higher than those of LBL group(P<0.05).Conclusion The application of PBL to physiological experiment teaching can effectively better the educational environment and improve the quality of teaching,which is worthy of promotion.
2017 Vol. 24 (18): 147-149 [
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138
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Application effect of clinical pathway of TCM in the intern′s teaching in the department of Endocrinopathy
WANG Zhen;LIU Feng;LI Zhan-hong;JI Bing;XIE Zheng-quan;XIA Chun-lan
ObjectiveTo observe the application effect of clinical pathways in the intern's teaching in the department of Endocrinology.MethodsThe clinical interns in the Department of Endocrinology in our hospital from June 2013 to May 2015 were divided into clinical pathway teaching group and traditional teaching group according to the random number table method.Clinical pathway teaching group was in strict accordance with the clinical pathway sheet for the implementation of the diagnosis and treatment plan,and the traditional teaching group carried out the diagnosis and treatment according to the previous theoretical teaching.The comprehensive results were compared before and after the internship in both groups and the differences of curative effects in the patients were compared.ResultsThe differences of the test results before the entry between the two groups were not significant.After different modes of clinical teaching,the test results in both groups were improved compared with those before the entry(P<0.05).However，the average score of students in the clinical pathway teaching group was better than that in the traditional teaching groups(P<0.01).The curative effect of the patients under control in the clinical pathway teaching group was also better than that in the traditional teaching group(P<0.05).ConclusionCompared with traditional teaching methods，the clinical pathways teaching method have significant advantages,which is suggested to be widely promoted in clinical teaching.
2017 Vol. 24 (18): 150-152 [
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A case of massive congenital chylothorax newborn with severe asphyxia at birth and literature review
WANG Xiao-dong;LI Ming;QI Hai-bin;HUANG Yu-lan;ZOU Na;WANG Chao-jun
To explore resuscitation,early diagnosis and treatment of newborn with large number of congenital chylothorax,this paper has analyzed a case of severe asphyxia at birth as the main clinical manifestations of congenital chylothorax neonatal diagnosis and treatment process，and through literature review,summarizes the experience of diagnosis and treatment of congenital chylothorax.ResultsShows that the cases in the prenatal diagnosis of a large number of pleural effusion,the prompt resuscitation,respiratory support,chest decompression,parenteral nutrition,the children recovered and discharged from the hospital,and analyze the related literature,summarize the causes of neonatal congenital chylothorax,diagnosis and treatment.So massive congenital chylothorax is easy to cause severe neonatal asphyxia,resuscitation,ventilator,chest drainage and nutritional support are the main treatments.
2017 Vol. 24 (18): 153-155 [
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Clinical observation of personalized nursing intervention on hand-foot syndrome induced by Capecitabine
FENG Shao-lan;ZHONG Mei-hua;MU Lei-lei
ObjectiveTo explore the effect of personalized nursing intervention on hand-foot syndrome induced by Capecitabine.MethodsA total of 200 patients in our hospital from January 2012 to January 2016 were selected and divided into the observation group and the control group according to the random number table method,with 100 cases in each group.The control group was given routine nursing care,while the observation group were treated with personalized nursing intervention.The incidence of hand-foot syndrome and nursing satisfaction were compared between two groups.ResultsThe incidence of hand-foot syndrome in the observation group was lower than that in the control group,the nursing satisfaction was higher than that in the control group,and the differences were statistically significant(P<0.05).Conclusion Personalized nursing intervention can effectively reduce the incidence of hand-foot syndrome induced by Capecitabine and improve the patients′nursing satisfaction.The effect is accurateand.It is worthy of clinical application.
2017 Vol. 24 (18): 156-158 [
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Application of high quality nursing in perioperative period of infants congenital duodenal atresia
LIN Xue-qin;WANG Liu-juan;DU Xi-yin
ObjectiveTo investigate the effect of high quality nursing in perioperative period of congenital duodenal atresia in infants.Methods80 infants with congenital duodenal atresia were selected in our hospital from January 2013 to January 2016,and they were randomly divided into observation group and control group,with 40 cases in each group,the control group were given routine perioperative nursing intervention of congenital duodenal atresia,the observation group was given high quality nursing care.The postoperative complications of two groups were observed,the curative effect was evaluated,and the nursing satisfaction of the two groups was investigated.ResultsThe incidence of postoperative complications was 7.5%in the observation group and 25.0%in the control group.The postoperative complications in the observation group was lower than those in the control group,the difference was statistically significant(P<0.05).The effective rate was 97.5%in the observation group and 80.0%in the control group.The effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).The nursing satisfaction of family members of children in the observation group was 95.0%,and the satisfaction degree of family members of children in the control group was 77.5%.The nursing satisfaction of the family members in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).ConclusionThe high quality nursing intervention is helpful to reduce the postoperative complications and improve the prognosis of neonates with congenital duodenal atresia,and the nursing effect is remarkable.
2017 Vol. 24 (18): 159-161 [
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127
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Influence of path based health education on negative emotions and life quality in patients with lung cancer
HUANG Xin-wu;HU Ying;NI Xing-hui;LIU Yan
ObjectiveTo investigate influence of path based health education on negative emotions and life quality in patients with lung cancer.Methods64 patients with lung cancer were selected in hospital from December 2015 to December 2016,who were randomly divided into two groups.32 patients received traditional health education as control group,32 patients received path based health education as observation group.Negative emotion,life quality,nursing effect were compared between two groups.ResultsAfter health education,SAS score and SDS score in two groups was decreased compared with before health education,and SAS score[(36.5±2.7)points],SDS score[(30.2±1.6)points]in observation group were lower than those of the control group[(46.2±3.9),(36.1±2.8)points],the differences were statistically significant(P<0.05);psychological function score,physical function score,role function score,cognitive function score,social function score increased in two groups,psychological function score[(61.3±4.2)points],physical function score[(51.6±4.7)points],role function score[(63.9±3.1)points],cognitive function score[(68.5±3.0)points],social function score[(64.3±2.7)points],health education compliance rate(93.8%),treatment compliance(90.6%),nursing satisfaction(96.9%)in observation group were higher than control group [(50.2±3.4)points,(43.8±3.6)points,(54.6±3.8)points,(57.9±4.2)points,(55.7±3.5)points,56.2%,62.5%,80.0%],the differences were statistically significant(P<0.05).ConclusionPath based health education can improve negative emotions of patients with lung cancer,which can also improve their life quality and worth of clinical application.
2017 Vol. 24 (18): 162-165 [
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Analysis of factors influencing breastfeeding after cesarean section and nursing measures
XIANG Huan;HUANG Xiao-li;CHEN Yue-lan
ObjectiveTo analyze the factors influencing breastfeeding after cesarean section and nursing measures.Methods60 cases of cesarean section in our hospital from February 2014 to January 2016 were selected and were divided into two groups according to the responsibility group.Puerperas received
traditional nursing acted as the control group(n=30),while puerperas received targeted nursing acted as the observation group(n=30).The breastfeeding rate,nursing satisfaction and lactation score were compared betweeh two groups.ResultsThe breastfeeding rate(96.67%)and nursing satisfaction (100.00%)in 3 d after cesarean section in the observation group were higher than that in the control group(70.00%,70.00%).The lactation score in 48,72 h after cesarean section[(2.13±0.24),(2.75±0.63)points]were higher than those in the control group[(1.24±0.32),(1.82±0.34)points],and the differences were statistically significant(P<0.05).ConclusionThe analysis of breastfeeding factors after maternal cesarean section,and the implementation of targeted care,can improve their breastfeeding rate,nursing satisfaction and lactation score,the effect is remarkable,worthy of clinical practice in the promotion.
2017 Vol. 24 (18): 166-168 [
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Application of pain nursing in patients with hemorrhoid surgery
ZHONG Xiao-juan
ObjectiveTo explore the application effect of pain nursing in patients with hemorrhoid surgery.MethodsFrom June 2014 to June 2016,200 patients with hemorrhoid surgery in our hospital were selected as the research objects.According to their willing,they were evenly divided into the observation group(n=100)and the control group(n=100).Patients in the control group were provided with regular nursing,while in the observation group were given pain nursing on the basis of the control group.The pain level,nursing satisfaction,treatment compliance and knowledge mastery were compared between two groups.ResultsThe pain level in the observation group was significantly lower than that in the control group (P＜0.05),the nursing satisfaction,treatment compliance and knowledge mastery were all better than those in the control group,and the differences were statistically significant(P<0.05).ConclusionIn patients with hemorrhoids surgery,effects on all aspects including pain level,nursing satisfaction,treatment compliance,etc.are improved after adding pain nursing.
2017 Vol. 24 (18): 169-171 [
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126
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Efficacy of individualized nursing on blood pressure control and medication compliance of patients with maintenance hemodialysis hypertension
ZHANG Xian
ObjectiveTo explore the Efficacy of individualized nursing on blood pressure control and medication compliance of patients with maintenance hemodialysis.Methods131 patients with maintenance hemodialysis in our hospital from April 2013 to April 2016 were randomly divided into the control group(67 cases)and the observation group(64 cases).The patients in the control group were treated with routine nursing,while patients in the observation group were given individualized nursing.Blood pressure control,nursing satisfaction,medication compliance and complications were compared between two groups.ResultsAfter nursing intervention,the compliance of the patients in the observation group was higher than that in the control group(P＜0.05).The incidence of complications and blood pressure in the observation group was lower than that in the control group,and the differences were statistically significant(P<0.05).ConclusionIndividualized nursing has a positive effect on blood pressure control and drug compliance in patients with maintenance hemodialysis,and it has obvious inhibitory effect on the appearance of complications,and it is worthy to be popularized.
2017 Vol. 24 (18): 172-174 [
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135
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Analysis of operating room nursing cooperation in patients undergoing total laparoscopic left hepatic lobectomy
BAI Guang-rong
ObjectiveTo explore the efficacy of operating room nursing cooperation in patients undergoing total laparoscopic left hepatic lobectomy.MethodsA total of 120 patients undergoing total laparoscopic left hepatic lobectomy in our hospital from from January 15th2016 to January 24th2017 were selected and randomly divided into two groups,with 60 cases in each group.The patients in the control group were given routine nursing care,while the patients in the observation group were given operating room nursing cooperation.The hospitalization time,the exhaust time,the time of getting out of bed and the incidence of complications were compared between the two groups.ResultsThe hospitalization time,the exhaust time,the time of getting out of bed in the observation group[(12.51±2.12)d,(40.15±5.16)h,(28.10±8.15)h]were shorter than those in the control group [(17.45±4.15)d,(78.35±6.65)h,(49.05±8.26)h],the incidence of complications(3.33%)was lower than that in the control group (18.33%),and the differences were statistically significant(P<0.05).ConclusionThe efficacy of operating room nursing cooperation in patients undergoing total laparoscopic left hepatic lobectomy is significant,which can shorten the hospital stay,exhaust time and the time of getting out of bed and can decrease the incidence of complications,it is worthy of clinical application.
2017 Vol. 24 (18): 175-177 [
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Clinical efficacy of healthy education care model in eldly patients with osteoporosis hip fracture
LIU Jiang-mei;CHEN Chun-xu;YE Jin-fen;TANG Chao
ObjectiveTo analyze the clinical efficacy of healthy education care model in old patients with osteoporosis hip fracture,and to explore its application value.Methods70 eldly patients with osteoporosis hip fracture in our hospital from January 1st2014 to January 1st2016 were selected and were randomly divided into the control group (n=35)and the observation group (n=35)by the international alphabet were divided.The control group was given routine nursing care,while the observation group was given health education care mode.The WOMAC score,recurrence rate and nursing satisfaction were compared between two groups.ResultsBefore nursing,there were no significant differences of WOMAC scores between two groups(P>0.05);after nursing,the WOMAC scores in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).There were no significant differences of recurrence rate between two groups(P>0.05).The nursing satisfaction in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).ConclusionHealth education in elderly patients with osteoporotic hip fracture can significantly improve the total WOMAC score of the hip joint,reduce the recurrence rate of fracture and improve the nursing satisfaction,and it is worthy to be popularized in clinical practice.
2017 Vol. 24 (18): 178-180 [
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Application effect of cluster nursing care on patients with continuous blood purification
LIU Jin-ling;FU Chu-lei
ObjectiveTo explore the Application effect of cluster nursing care on patients with continuous blood purification.Methods88 patients received
continuous blood purification treatment in our hospital from January 2015 to June 2016 were selected as the observation objects and were divided into the observation group (n=44)and the control group(n=44)according to the random number table.The patients in the control group were given routine nursing,and patients in the observation group were given cluster nursing intervention.After the treatment,the CRBSI occurrence,catheter time,hospital stay,CRBSI duration,the CRBSI time andnursing satisfaction were compared between two groups.ResultsThe CRBSI rate of the observation group was 6.8%,significantly lower than 22.7%in the control group,and the difference was statistically significant(P<0.05);The catheter time,hospital stay and CRBSI duration of the observation group were respectively(22.9±7.1),(30.8 ±8.6),(10.4±5.5)d,which were significantly shorter than(30.5±9.6),(42.4±10.3),(11.4±4.7)d of the control group,and the differences were statistically significant(P<0.05);CRBSI time of the observation group was(16.0±5.3)d,which was significantly longer than(11.4±4.7)d of the control group,and the difference was statistically significant(P<0.05);The nursing satisfaction of the observation group was 86.4%,which was significantly higher than 65.9%of the control group,and the difference was statistically significant(P<0.05).ConclusionCluster nursing care on catheter-related bloodstream infection in patients with continuous blood purification has the good effect,significantly reduces the CRBSI incidence,can shorten the treatment time,and greatly improve the patients′satisfaction,so it is worth of clinical promotion.
2017 Vol. 24 (18): 181-183 [
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Influence of nursing intervention of Traditional Chinese Medicine on blood glucose control in elderly patients with type 2 diabetes mellitus
SA Wen-juan;LI Xin-nan;ZHANG Yan-mei
ObjectiveTo explore the influence of nursing intervention of Traditional Chinese Medicine on blood glucose control in elderly patients with type 2 diabetes mellitus.Methods200 patients with type 2 diabetes mellitus in our hospital from October 2013 to January 2015 were selected and were divided into the observation group and the control group based on the sequence of admission to the hospital,with 100 cases in each group.The control group was given conventional nursing intervention,while the observation group was given the nursing intervention of Traditional Chinese Medicine.The fasting blood glucose,2-hour postprandial blood glucose and nursing satisfaction were compared between two groups.ResultsBefore intervention,there were no significant differences between the levels of fasting blood glucose,2-hour postprandial blood glucose in two groups(P>0.05);after intervention,those in two groups were all decreased,and compared with those before intervention,the differences were statistically significant(P<0.05).And those in the observation group was lower than those in the control group,and the differences were statistically significant(P<0.05).The nursing satisfaction in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).ConclusionUsing nursing intervention of Traditional Chinese Medicine in patients with type 2 diabetes mellitus can effectively control the level of blood glucose and improve the nursing satisfaction.
2017 Vol. 24 (18): 184-186 [
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Efficacy of humanized nursing intervention combined with hot dressing acupoint on two lungs with Seedspowder in children with infantile pneumonia
CHEN Xiao-rong
ObjectiveTo investigate the effect of humanized nursing intervention on the therapeutic effect of five children with heat preservation and lung acupoints on children pneumonia.Methods84 cases of pediatric pneumonia treated in our hospital from January to December 2016 were selected.Two groups were all treated with Azithromycin antiinflammatory and antitussive and antiasthmatic and atomization,antipyretic therapy,combined with hot dressing acupoint on two lungs with Seedspowder.They were randomly divided into two groups,with 42 cases in each group.The control group was given routine nursing,the observation group was given the humanized nursing intervention.The total effective rate,body temperature returned to normal time,the disappearance time of cough,wheezing and rale,the nursing satisfaction were compared between two groups.ResultsThe total effective rate in the observation (96%)was higher than that in the control group (78%),the body temperature returned to normal time,the disappearance time of cough,wheezing and rale were shorter than those in the control group,the nursing satisfaction(98%)was higher than that in the control group(70%),and the differences were statistically significant(P<0.05).ConclusionIn children with pneumonia,humanized nursing intervention combined with hot dressing acupoint on two lungs with Seedspowder can significantly increase the clinical efficacy,improve the clinical symptoms,enhance the children′s family on nursing satisfaction,which is conducive to disease recovery as soon as possible.
2017 Vol. 24 (18): 187-189转193 [
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Application of nursing measures of integrated traditional Chinese and western medicine in vomiting of patients with malignant tumor after chemotherapy
DENG Wu-xiu;HUA Mei;LUO Yan
ObjectiveTo explore the application of nursing measures of integrated traditional Chinese and western medicine in vomiting of patients with malignant tumor after chemotherapy.Methods200 patients with malignant tumor and received
chemotherapy and vomiting symptoms in our hospital from January 2014 to January 2016 were selected and divided into the observation group and the control group with digital and random grouping,with 100 cases in each group.The control group was given traditional Chinese nursing intervention,while the observation group was given nursing measures of integrated traditional and western medicine.The clinical efficacy and nursing satisfaction were compared between two groups.ResultsThe efficacy rate and nursing satisfaction in the observation group (95.0%,96.0%)were higher than those in the control group(84.0%,82.0%),and the differences were statistically significant(P<0.05).Conclusion Nursing measures of integrated traditional Chinese and western medicine can significantly improve the patient′s symptoms of vomiting during chemotherapy in patients with malignant tumor,improve the quality of life of patients,improve patient satisfaction,closer relationship between nurses and patients.It has important clinical application value.
2017 Vol. 24 (18): 190-193 [
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Efficacy of applying clinical nursing pathway on health education in patients with bronchial asthma
WANG Xiao-ying
ObjectiveTo explore the efficacy of applying clinical nursing pathway on health education in patients with bronchial asthma.MethodsA total of 30 patients with bronchial asthma in our hospital from January 2010 to December 2016 were selected as research objects and randomly divided into the observation group (n=16)and the control group(n=15).The control group was given health education in a traditional way,while the observation group was given health education by the clinical pathway.The rate of mastering related knowledge and skills on the disease,treatment compliance and nursing satisfaction were compared between two groups.ResultsThe rate of mastering related knowledge and skills on the disease,treatment compliance and nursing satisfaction in the observation group(87.5%,87.5%,93.8%)were higher than those in the control group(73.3%,66.7%,93.8%),and the differences were statistically significant(P<0.05).ConclusionThe application of clinical nursing pathway to health education in patients with bronchial asthma can significantly enhance the health education effect,strengthen the communication between nurse and patient,and play positive roles in improving the nursing quality and patient′s satisfaction.
2017 Vol. 24 (18): 194-196 [
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