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Quick Search     Adv Search 2021 Vol. 28, No. 17 Published: 2021-06-18   4 Application of NRS2002 nutritional risk screening in patients with newly diagnosed gastric cancer HUANG Ling-li Objective To evaluate the nutritional status of newly diagnosed gastric cancer patients,to explore the correlation between NRS2002 nutritional risk screening and outcome measurements,so as to guide nutritional treatment.Methods A total of 93 newly diagnosed gastric cancer patients from February to June 2018 were selected as the research objects in department of gastric surgery of a cancer specialist hospital from Nanjing City.NRS2002 was used for nutritional risk screening within 48 hours of admission.According to the NRS2002 score,they were divided into nutritional risk group(NRS2002 score ≥3 points)and non-nutritional risk group(NRS2002 score ＜3 points).At the same time,PG-PGA nutritional assessment classification and physical examination were performed,blood routine and biochemical indicators were tested,multi-frequency bioelectrical impedance analysis was used to detect body composition,and statistical analysis of the results was made.Results A total of 93 patients were enrolled in the group,of whom 47.31%were at nutritional risk.There was statistically significant difference in the PG-SGA grading distribution between the two groups(P＜0.05).The serum albumin,hemoglobin,skeletal muscle mass,intra-cellular water,fat free mass index,and skeletal muscle index in the nutritional risk group were lower than those in the non-nutritional risk group,and the differences were statistically significant(P＜0.05).There were no statistically significant differences in other indexes between the two groups(P＞0.05).Conclusion NRS2002 nutritional risk screening has great concordance in PG-SGA grades,serum albumin,hemoglobin,skeletal muscle index and other nutritional indicators.It is not only a reliable and rapid nutritional risk screening tool,but also can reflect nutritional status.Most of all,combining NRS2002 with these nutritional indexes can more accurately and comprehensively understand the nutritional status of patients and improve the prognosis of patients. 2021 Vol. 28 (17): 4-7 [Abstract] ( 44 ) HTML (38 KB)  PDF  (0 KB)  ( 5 ) 8 Effect of thoracic paravertebral nerve block combined with general anesthesia on cellular immunity and pain in patients undergoing endoscopic radical resection of lung cancer GUO Shan-liang; SU Hua-feng;LIU Yan-long; FAN Long-cheng; KUANG Song-tao; ZHANG Ming-sheng Objective To investigate the effect of ultrasound-guided thoracic paravertebral nerve block combined with general anesthesia on postoperative cellular immunity and pain in patients undergoing endoscopic radical resection of lung cancer.Methods A total of 60 patients with lung cancer admitted to Jiangxi Provincial People′s Hospital from June 2018 to October 2020 were selected as the research subjects,and divided into group P(30 cases)and group C(30 cases)according to random number table method.Group C received general anesthesia,and group P received thoracic paravertebral nerve block combined with general anesthesia.T lymphocyte subsets(CD3+,CD4+,CD4+/CD8+),intraoperative amounts of remifentanil and propofol,and visual analog scale(VAS)scores at cough at 2,6,12,24 and 36 h after surgery,at 12,24,48 h postoperative intravenous analgesia pump pressure frequency and postoperative relief analgesia rate were compared between the two groups.Results There were no significant differences in the levels of T lymphocyte subsets before and 48 h after operation between the two groups(P＞0.05).CD3+,CD4+and CD4+/CD8+in group P were higher than those in group C after operation and 24 h after operation,the differences were statistically significant(P＜0.05).The dosage of Remifentanil and Propofol in group P were lower than those in group C,and the differences were statistically significant(P＜0.05).The VAS score of cough in group P were lower than those in group C at 2,6 and 12 h after operation,and the differences were statistically significant(P＜0.05).At 12,24 h after surgery,the frequency of automatic pump pressing in group P were less than those in group C,and the remedial analgesia rate in group P was lower than that in group C,the differences were statistically significant(P＜0.05).Conclusion Thoracic paravertebral nerve block combined with general anesthesia in patients with thoracoscopic radical resection of lung cancer can provide satisfactory intraoperative and postoperative analgesic effects,reduce the usage amount of general anesthesia,and improve the cellular immune function of patients after surgery,which is worthy of clinical promotion and application. 2021 Vol. 28 (17): 8-11转19 [Abstract] ( 45 ) HTML (49 KB)  PDF  (0 KB)  ( 7 ) 12 Mechanism analysis of Shensu Decoction in treating chronic bronchitis based on network pharmacology ZHU Gao-feng;CHEN Rui;ZHANG Yi-ming;TANG Lei▲ Objective To explore the mechanism of Shensu decoction in treating chronic bronchitis based on network pharmacology.Methods Screening the active ingredients and action targets of Shensu Decoction from the establishment of the Chinese Medicine Systematic Pharmacological Analysis Platform(TCMSP)until September 2020.Disease targets for chronic bronchitis were obtained from GeneCards database(up until September 2020).Cytoscape 3.7.0 software was used to draw the component-target network,Protein-protein interaction(PPI)analysis,gene ontology(GO)analysis and Kyoto Encyclopedia of Genes and Genomes(KEGG)analysis were performed on related targets using R language scripts.Results A total of 160 active components of Shensu Decoction,such as quercetin,kaempferrol and luteolin D ethyl ester,might act on 154 targets core through 175 pathways,such as tumor necrosis factor(TNF)pathway.Conclusion On the surface of network pharmacology,the active ingredients contained in Shensu Deccoction may have potential preventive and therapeutic effect on chronic bronchitis through anti-inflammatory effect. 2021 Vol. 28 (17): 12-19 [Abstract] ( 50 ) HTML (45 KB)  PDF  (0 KB)  ( 7 ) 20 Study on the stability of Kulian Kangfu Lotion YE Bing-huang;CHEN Ze-wei▲ Objective To discuss the stability of Kulian Kangfu Lotion.Methods The stability of Kulian Kangfu Lotion under severe and ordinary conditions was investigated with the characteristics,identification,pH value and content of berberine hydrochloride as the indexes.Results Kulian Kangfu Lotion has stable effect on strong light,high humidity and high temperature.After 6 months of accelerated test and 12 months of long-term test,Kulian Kangfu Lotion sample showed no obvious change in its properties.The characteristic spots of Coptidis Rhizoma,Borneol and Sophora flavestifolia in Kulian Kangfu Lotion were clearly visible.The pH value of Kulian Kangfu Lotion sample was stable,and the content of the sample had no obvious loss.Conclusion Kulian Kangfu Lotion has good stability and the rationality of the preparation process was further verified. 2021 Vol. 28 (17): 20-24转28 [Abstract] ( 53 ) HTML (42 KB)  PDF  (0 KB)  ( 5 ) 25 Clinical effect of 3D printing in the assisted treatment of unstable pelvic fractures LIANG Jian-bin ;YAO Fu-hua▲ ;HUANG Jian-hua Objective To explore the clinical effect of 3D printing technology in the assisted treatment of unstable pelvic fractures.Methods The clinical data of 50 patients with unstable pelvic fractures admitted to Huiya Hospital of the First Affiliated Hospital,Sun Yat-sen University from January 2015 to December 2019 were retrospectively analyzed.According to the different treatment methods,they were divided into the routine group(n=25)and the study group(n=25).The routine group was treated with post erior approach,sacroiliac joint fixed with spinal pelvic fixation,and the study group was treated with 3D printing technique on the basis of routine group.The operative time,intraoperative bleeding volume,screw dislocation rate,fracture reduction quality,pelvic function recovery and complications were compared between the two groups.Results The operation time in the study group was shorter than that in the routine group,the intraoperative bleeding volume and screw dislocation rate of the study group were less than those of the routine group,the differences were statistically significant(P＜0.05).There was no significant difference in fracture reduction quality in the two groups(P＞0.05).There was no significant difference in the quality of pelvic function recovery in the two groups(P＞0.05).The total incidence of complications in the study group was lower than in the conventional group,and the difference was statistically significant(P＜0.05).Conclusion 3D printing technology in the assisted treatment of unstable pelvic fractures,pelvic fracture repair in advance to carry out accurate evaluation norms,help to shorten the operation time,reduce surgical trauma and complications,and has good fracture repair quality and functional recovery effect. 2021 Vol. 28 (17): 25-28 [Abstract] ( 56 ) HTML (36 KB)  PDF  (0 KB)  ( 7 ) 29 Application study of directional injection cannula in senile osteoporotic vertebral compression fracture TAN Zhen-nan; LIU Hu ;REN Ming-liang ;LIU Dong-bin ;CHEN Guo-xiong ;GUO Dong-xiao Objective To investigate the clinical efficacy of directional injection cannula in the percutaneous vertebroplasty treatment of senile osteoporotic vertebral compression fractures.Methods A total of 162 senile patients with osteoporotic vertebral compression fractures treated in Nanhai District People′s Hospital of Foshan City from January 2018 to December 2019 were selected as the research objects,and they were divided into the control group(80 cases)and the observation group(82 cases)according to the random number table method.The control group was injected with standard anterior open-ended injection cannula for bone cement injection,while the observation group was injected with directional injection cannula.Vertebroplasty in both groups was unilateral injection via pedicle.The leakage of bone cement,visual analogue score and Oswestry disability index score(ODI score)before and after the first days and 3 months were compared between the two groups.Results The two groups were successfully completed the operation and postoperative follow-up,and there was no adverse reactions occurred.There was no significant difference in operation time and bone cement injection between the two groups(P＞0.05).The leakage rate of bone cement in the observation group was lower than that of the control group,the difference was statistically significant(P＜0.05).The visual analogue scale score and the ODI score at the first day after operation and 3 months after operation were lower than those before operation,the differences were statistically significant(P＜0.05).There was no significant difference in visual analogue score and ODI score between the two groups at different time points(P＞0.05).Conclusion In the treatment of osteoporotic vertebral fracture with vertebroplasty,directional injection cannula can guide the flow direction of bone cement injection process through the improvement of injection mode,so as to obtain good bone cement dispersion effect and reduce the leakage rate of bone cement. 2021 Vol. 28 (17): 29-34 [Abstract] ( 41 ) HTML (48 KB)  PDF  (0 KB)  ( 7 ) 35 Clinical effect and safety of different doses of Caffeine Citrate in the treatment of apnea in premature infants QIN Su-fang; LIAO Hai-rong; LI Hong-ming ;XU De-quan Objective To explore the clinical effect and safety of Caffeine Citrate at different maintenance doses in the treatment of apnea in premature infants.Methods A total of 110 premature infants with apnea in Neonatal Intensive Care Unit of Yueyang Maternal and Child Health Hospital from January 2018 to December 2019 were selected as the research subjects.According to the random number table method,they were divided into an experimental group and a control group,with 55 cases in each group.Both groups were given a loading dose of Caffeine Citrate with 20 mg/kg for the first occurrence of apnea.After 24 hours,the experimental group was given maintenance dose of high-dose Caffeine Citrate with 10 mg/(kg·d),and the control group was given maintenance dose of low-dose Caffeine Citrate with 5 mg/(kg·d).The duration of apnea,the onset frequency of apnea,the success rate of withdrawal,the duration of invasive ventilator,the duration of non-invasive ventilator,the duration of oxygen therapy,the total length of hospital stay,and the incidence of various short-term complications were compared between the two groups.Results The frequency and duration of apnea in the experimental group were lower than those in the control group,and the success rate of withdrawal was higher than that in the control group,the differences were statistically significant(P＜0.05).There were no significant differences in invasive ventilator use time,non-invasive ventilator use time,oxygen therapy duration and total hospital stay between the two groups(P＞0.05).There were no significant differences in the incidence rates of short-term complications(bronchopulmonary dysplasia,necrotizing enterocolitis,ductus arteriosus opening)between the two groups(P＞0.05).Conclusion Compared with low-dose of Caffeine Citrate,high-dose of Caffeine Citrate can effectively reduce the frequency of apnea attacks in children,shorten the duration of apnea,improve the success rate of withdrawal,and does not increase the incidence of complications.It has better efficacy and is worthy of promotion and application. 2021 Vol. 28 (17): 35-38转51 [Abstract] ( 51 ) HTML (42 KB)  PDF  (0 KB)  ( 7 ) 39 Research progress of traditional Chinese medicine in treating diabetic ketoacidosis XIONG Jia Diabetic ketoacidosis(DKA)is one of the acute complications of diabetic patients.The disease is acute and develops rapidly.Without timely diagnosis and treatment,it may lead to coma,shock,or even endanger the patients′lives.DKA is a further aggravation of diabetes disease.Traditional Chinese medicine has earlier recognized the etiology and pathogenesis of diabetes,and many classic prescriptions and traditional Chinese medicine have been spread.This article collects relevant literature in the past 5 years,sorts out and analyzes DKA Chinese medicine treatment and modern research,summarizes the research progress of DKA classification and treatment,modern Chinese medicine preparations and pharmacology,in order to provide important information for the clinical treatment of DKA in traditional Chinese medicine. 2021 Vol. 28 (17): 39-42 [Abstract] ( 53 ) HTML (40 KB)  PDF  (0 KB)  ( 7 ) 43 Research progress of Hepcidin in the occurence and development of chronic kidney disease WANG Fu-ju; YU Li-xia▲ Chronic kidney disease(CKD)patients often have multiple complications,and the incidence of renal anemia(RA)gradually increases with the course of CKD.RA not only prolongs the hospital stay of CKD patients,but also affects the survival rate of patients.Therefore,treatment of anemia for CKD patients is particularly critical.There are many factors that cause RA.The most important factor is the lack of erythropoietin(EPO)and abnormal iron metabolism.Abnormal iron metabolism leads to insufficient or relative lack of iron.Hepcidin plays an important role in the regulation of iron metabolism abnormalities.This article mainly reviews the function of Hepcidin,related signal pathways and the relationship of Hepcidin in the occurrence and development of CKD,and provides a basis for clinical treatment of RA. 2021 Vol. 28 (17): 43-47 [Abstract] ( 40 ) HTML (48 KB)  PDF  (0 KB)  ( 6 ) 48 Sequential application of high-flow nasal cannula in patients with chronic obstructive pulmonary disease after mechanical ventilation weaning WU Li-xia ;XU Xing-ling ;LI Xiao-xia; RONG Yong-zhang Objective To investigate the sequential application effect of high-flow nasal cannula(HFNC)in patients with chronic obstructive pulmonary disease(COPD)after mechanical ventilation weaning.Methods A total of 82 COPD patients who were treated by mechanical ventilation from the Department of severe medicine,People′s Hospital of Jiangmen from January 2019 to October 2020 were selected as the research objects,and they were divided into the experimental group and the control group according to the order of admission time,with 41 cases in each group.The experimental group was connected with HFNC after withdrawal,and the control group was given oxygen inhalation with medium flow in the endotracheal tube after withdrawal.The respiratory rate(RR),heart rate(HR),arterial oxygen saturation(SaO2),arterial partial pressure of oxygen(PaO2),arterial partial pressure of carbon dioxide(PaCO2),incidence of secondary mechanical ventilation and time of extubation were compared between the two groups after treatment.Results After 12,24 h of treatment,there was no significant difference in RR and HR between the two groups(P＞0.05).The indexes of SaO2 and PaO2 in both groups after 24 h of treatment were higher than those after 12 h of treatment,and the differences were statistically significant(P＜0.05);PaCO2 index in the experimental group after 24 h of treatment was lower than that after 12 h of treatment,and the difference was statistically significant(P＜0.05).The total incidence of secondary mechanical ventilation in the experimental group was lower than that in the control group,and the time of extubation in the experimental group was shorter than that in the control group,the differences were statistically significant(P＜0.05).Conclusion In the clinical diagnosis and treatment of COPD patients with mechanical ventilation after weaning sequential treatment,HFNC is more helpful to reduce the incidence of secondary mechanical ventilation and achieve the goal of early extubation,which is worthy of clinical application. 2021 Vol. 28 (17): 48-51 [Abstract] ( 49 ) HTML (36 KB)  PDF  (0 KB)  ( 6 ) 52 Application effect of Esomeprazole on the treatment of adult gastric ulcer during active phase HE Xiao-rui ;ZHAO Feng-e Objective To investigate the application effect of Esomeprazole in the treatment of adult active gastric ulcer.Methods A total of 112 adult patients with active gastric ulcer treated in Iron Coal General Hospital of Liaoning Health Industry Group from February 2019 to May 2020 were selected as the research objects.According to random number table method,they were divided into the control group and the observation group,with 56 cases in each group.The observation group was treated with Esomeprazole,and the control group was treated with Omeprazole,and both groups were treated with Clarithromycin and Amoxicillin.After 6 weeks of treatment,the total effective rate and clinical symptom score of the two groups were compared.Results The clinical effective rate of observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).Before treatment,there was no statistically significant difference in clinical symptoms score between the two groups(P＞0.05).After treatment,the clinical symptom score of the observation group was lower than that of the control group,the difference was statistically significant(P＜0.05).Conclusion Esomeprazole treatment for adult patients with active gastric ulcer can effectively improve the clinical symptoms,improve the healing quality of ulcer,and improve the clinical efficacy,which is worthy of popularization and application. 2021 Vol. 28 (17): 52-54 [Abstract] ( 44 ) HTML (30 KB)  PDF  (0 KB)  ( 7 ) 55 Effect of mechanical ventilation in the rescue and treatment of critical asthma TONG Yi Objective To explore the effect of mechanical ventilation in the rescue and treatment of critical asthma.Methods A total of 60 patients with critical asthma from September 2018 to September 2020 in the Fourth People′s Hospital of Shenyang City were selected as subjects.The patients were divided into control group(30 cases)and experimental group(30 cases)by random number table method.The control group was treated with conventional treatment,and the experimental group was treated with non-invasive mechanical ventilation.Clinical treatment effect,pulmonary function indexes,blood gas indexes and total compliance rate were compared between the two groups.Results The total effective rate of the experimental group was higher than that of the control group,and the difference was statistically significant(P＜0.05).The arterial partial pressure of oxygen(PaO2)in the experimental group was higher than that in the control group after treatment,and the difference was statistically significant(P＜0.05).The arterial partial pressure of carbon dioxide(PaCO2)in the experimental group was lower than that in the control group,and the difference was statistically significant(P＜0.05).The PaO2 in the experimental group after treatment was higher than that in the control group,and the difference was statistically significant(P＜0.05).The PaCO2 in the experimental group after treatment was lower than that in the control group,the difference was statistically significant(P＜0.05).After treatment,the forced expiratory volume in first second(FEV1)and the percentage of forced expiratory volume in first second in forced vital capacity(FEV1/FVC)in the experimental group were higher than those in the control group,with statistically significant differences(P＜0.05).The total compliance rate of the experimental group was higher than that of the control group,and the difference was statistically significant(P＜0.05).Conclusion The application of non-invasive mechanical ventilation in the rescue and treatment of critical asthma patients has a significant effect,which can significantly improve the lung function,blood gas indexes and treatment compliance of patients,and is worthy of clinical application. 2021 Vol. 28 (17): 55-58 [Abstract] ( 42 ) HTML (36 KB)  PDF  (0 KB)  ( 6 ) 59 Clinical effect of Metformin combined with Sitagliptin in the treatment of patients with type 2 diabetes LI Qiong;FAN Jun-xiu; PENG Wei; PANG Dong-yue;HU Jing-jing;ZHANG Li-zhi▲ Objective To investigate the clinical effect of Metformin combined with Sitagliptin in the treatment of patients with type 2 diabetes.Methods A total of 105 patients with type 2 diabetes who were treated in Shanghai Oriental Hospital from January 2017 to July 2020 who treated with Metformin alone and had poor glucose control effects were selected as the research objects.Among them,5 cases fell out,and 100 cases were finally enrolled.They were divided into group A(30 cases),group B(35 cases)and group C(35 cases)by random number table.Patients in group A continued to be treated with Metformin,patients in group B were treated with Metformin combined with Acarbose.Patients in group C were treated with Metformin combined with Sitagliptin.1,5-dehydroglucositol(1,5-AG),glycated hemoglobin(HbA1c),blood glucose ratio time within the target range(TIR)and the incidence of adverse reactions in three groups were compared before and after treatment.Results After intervention,the level of 1,5-AG in groups B and C were higher than that in group A at different visit periods,and the differences were statistically significant(P＜0.05).The 1,5-AG in group C was higher than that in group B,and the difference was statistically significant(P＜0.05).After intervention,HbA1c in group B and C were lower than group A,and the differences were statistically significant(P＜0.01).After intervention,there was no significant difference in HbA1c between group B and C(P＞0.05).After intervention,TIR of group B and C were higher than that of group A,and the differences were statistically significant(P＜0.01).After intervention,TIR in group C was higher than that in group B,and the difference was statistically significant(P＜0.01).The total incidence of adverse reactions in group A and C were lower than that in group B,and the differences were statistically significant(P＜0.05).There was no statistical significance in the total incidence of adverse reactions between group A and C(P＞0.05).Conclusion The combination of Metformin and Sitagliptin can significantly reduce HbA1c,and the patient′s blood glucose fluctuations will be smaller.It is a more optimized hypoglycemic treatment. 2021 Vol. 28 (17): 59-63 [Abstract] ( 45 ) HTML (49 KB)  PDF  (0 KB)  ( 6 ) 64 Clinical effect of Gliclazide combined with Acarbose in the treatment of type 2 diabetes mellitus TAN Qiu-ling; LUO Xiao-jing ;CHEN Qiao-rong Objective To explore the clinical effect of Gliclazide combined with Acarbose in the treatment of type 2 diabetes mellitus(T2DM).Methods A total of 100 cases of T2DM patients admitted to the People′s Hospital of Yangdong District in Yangjiang City from June 2019 to July 2020 were selected as the research objects.According to random number table method,they were divided into the control group and the observation group,with 50 cases in each group.The control group was given Acarbose treatment,while the observation group was given Gliclazide on the basis of the control group.The course of treatment was 12 weeks.The levels of fasting blood glucose(FPG),2 h postprandibular blood glucose(2 h PG),glycosylated hemoglobin(HbA1c),serum hypersensitive C-reactive protein(hs-CRP),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)and the incidence of adverse reactions during treatment were compared between the two groups before and after treatment.Results There were no statistically significant differences in the levels of FPG,2 h PG and HbA1c between the two groups before treatment(P＞0.05).After treatment,the levels of FPG,2 h PG and HbA1c in the two groups were lower than those before treatment,and the levels of FPG,2 h PG and HbA1c in the observation group were lower than those in the control group,the differences were statistically significant(P＜0.05).There were no statistically significant differences in the levels of hs-CRP,IL-6 and TNF-α between the two groups before treatment(P＞0.05).After treatment,the levels of hs-CRP,IL-6 and TNF-α of the two groups were lower than those before treatment,and the levels of hs-CRP,IL-6 and TNF-α of the observation group were lower than those of the control group,the differences were statistically significant(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion Gliclazide combining with Acarbose in the treatment of T2DM can effectively reducing the levels of FPG,2 h PG,HbA1c,hs-CRP,IL-6 and TNF-α,without increasing the adverse reactions. 2021 Vol. 28 (17): 64-66转70 [Abstract] ( 63 ) HTML (34 KB)  PDF  (0 KB)  ( 7 ) 67 Application effect of Daglijing combined with Valsartan Capsules in patients with type 2 diabetes mellitus complicated with newly developed hypertension HAO Yan-hong;WU Qing;LI Yun;WANG Ying-li;ZHANG Ying;LUO Ya-hui;LIU Yan-dong;ZHOU Li-jing Objective To explore the effect of Daglijing combined with Valsartan Capsules in patients with type 2 diabetes mellitus complicated with newly developed hypertension.Methods A total of 92 patients with type 2 diabetes mellitus complicated with newly developed hypertension who were admitted to the Department of Endocrinology in Beijing Jiangong Hospital from January to December 2019 were selected as the research objects.All the patients were divided into combination therapy group and monotherapy group by the random number table method,with 46 cases in each group.Patients in the combination therapy group were treated with Daglijing combined with Valsartan Capsules,and patients in the monotherapy group were treated with Valsartan Capsules.After 24 weeks of treatment,the systolic blood pressure(SBP),diastolic blood pressure(DBP),mean artery pressure(MAP),SBP control rate,DBP control rate,and both control rate of the two groups were compared.Results A total of 41 patients in the combined treatment group and 40 patients in the monotherapy group were included in statistical analysis.There were no statistically significant differences in SBP,DBP,MAP before treatment between the two groups(P＞0.05).The SBP,DBP and MAP of the two groups after treatment were lower than those before treatment,and the differences were statistically significant(P＜0.05).The SBP,DBP and MAP of the combination therapy group after treatment were lower than those in the monotherapy group,and the differences were statistically significant(P＜0.05).After treatment,the SBP compliance rate and both compliance rates in the combined treatment group were higher than those in the monotherapy group,and the differences were statistically significant(P＜0.05).There was no statistical significance in DBP compliance rate between the two groups(P>0.05).Conclusion The clinical effect of Daglijing combined with Valsartan Capsules is better in patients with type 2 diabetes mellitus complicated with newly developed hypertension. 2021 Vol. 28 (17): 67-70 [Abstract] ( 130 ) HTML (36 KB)  PDF  (0 KB)  ( 7 ) 71 Clinical effect of arthroscopy assisted percutaneous balloon expansion of bone cement filling treating Schatzker type Ⅱand Ⅲtibial plateau fracture CHEN Jin-min;CHEN Sui-sheng; XIA Bao-quan;LUO Xiao-jia;LU Cheng-hai;ZHOU Hong Objective To explore the clinical effect of arthroscopy assisted percutaneous balloon expansion of bone cement filling treating Schatzker type Ⅱand Ⅲtibial plateau fracture.Methods A total of 45 patients with Schatzker typeⅡand Ⅲtibial plateau fracture admitted to Baiyun District Maternal and Child Health Hospital of Guangzhou from February 2015 to May 2019 were selected as the research objects.The patients were divided into the control group(22 cases)and the observation group(23 cases)according to the random number table method.The control group was treated with open reduction and internal fixation,and the observation group was treated with arthroscopy assisted percutaneous balloon expansion of bone cement filling.The surgical indexes,the total incidence of adverse reactions,wound healing,visual analogue scale(VAS)score and hospital for special surgery knee(HSS)score were compared between the two groups.Results The operation time,incision length and hospitalization time in the observation group were shorter than those in the control group,the intraoperative bleeding volume in the observation group was less than that in the control group,the total incidence of adverse reactions in the observation group was lower than that in the control group,the wound healing in the observation group was better than that in the control group,the VAS score in the observation group was lower than that in the control group,the HSS score in the observation group was higher than in the control group,the differences were statistically significant(P＜0.05).Conclusion Arthroscopy assisted percutaneous balloon expansion of bone cement filling on Schatzker type Ⅱand Ⅲtibial plateau fracture could achieve good clinical effect.It is helpful to optimize the operation indexes,shorten the treatment time,reduce the incidence of postoperative dysplasia and pain,and promote the recovery of knee joint function,have low cost-performance.It is worth promoting. 2021 Vol. 28 (17): 71-74 [Abstract] ( 38 ) HTML (37 KB)  PDF  (0 KB)  ( 7 ) 75 Application effect of bone-setting manipulation combined with Taohe Chengqi Decoction in early treatment of thoracolumbar compressibility fracture without neurologic symptoms HUANG Bin;SHEN Li-ping;YIN Zong-yun; ZHOU Chong-gang;LYU Sui-ben;YU Xue-wen;LI Changjie;WANG Yang Objective To explore the application effect of bone-setting manipulation combined with Taohe Chengqi Decoction in early treatment of thoracolumbar compressibility fracture without neurologic symptoms.Methods A total of 80 patients with thoracolumbar compressibility fracture without neurologic symptoms admitted to Jiujiang Traditional Chinese Medicine Hospital from June 2017 to June 2020 were selected as the research objects.The patients were divided into the control group and the observation group according to random number table method,with 40 cases in each group.The control group was treated with low back cushion soft pillow,and the observation group was treated with bone-setting manipulation combined with Taohe Chengqi Decoction.The total effective rate was compared between the two groups,the anterior height of vertebral bodies,the posterior salient angle and the lumbar spine function(Oswestry dysfunction index[ODI])before and after treatment were compared between the two groups,and the complications of the two groups were recorded.Results The total effective rate of treatment in the observation group was higher than that in the control group,the difference was statistically significant(P＜0.05).After treatment,the anterior height of vertebral bodies of two groups was higher than that before treatment,the posterior salient angle of two groups was smaller than that before treatment,the ODI score of two groups was lower than that before treatment,and the anterior height of vertebral bodies in the observation group was higher than that in the control group,the posterior salient angle in the observation group was smaller than that in the control group,the ODI score in the observation group was lower than that in the control group,and the differences were statistically significant(P＜0.05).The total incidence of complications in the observation group was lower than that in the control group,the difference was statistically significant(P＜0.05).Conclusion The effect of bone-setting manipulation combined with Taohe Chengqi Decoction in early treatment of thoracolumbar compressibility fracture without neurologic symptoms is better.It could improve the anterior height of vertebral bodies,reduce the posterior salient angle,and have high safety. 2021 Vol. 28 (17): 75-78 [Abstract] ( 42 ) HTML (36 KB)  PDF  (0 KB)  ( 7 ) 79 Effect of anterior cruciate ligament reconstruction combined with platelet rich plasma on short-term postoperative posture stability and proprioceptive sense YANG Kang-hua Objective To investigate the effect of anterior cruciate ligament reconstruction combined with platelet rich plasma on short-term postoperative posture stability and proprioceptive sense.Methods From March 2018 to August 2020,a total of 40 patients with anterior cruciate ligament rupture treated in Ganzhou People′s Hospital were selected,According to the random number table method,they were divided into observation group and control group,with 20 cases each.The control group was given anterior cruciate ligament reconstruction,and the observation group was given anterior cruciate ligament reconstruction combined with platelet-rich plasma treatment,the results of star excursion balance test and the degree of recovery of proprioceptive sense were compared between the two groups.Results Before operation,there was no statistical significant difference on the relative displacement distance in lateral direction after star excursion balance test between both groups(P＞0.05);At 3 months after operation,the relative displacement distance in lateral direction after star excursion balance tests in two group were greater than those before operation,with statistical significant differences(P＜0.05);At 3 months after operation,the relative displacement distance in lateral direction after star excursion balance test in the observation group was larger than that in the control group,with statistical significant difference(P＜0.05).At 3 months after operation,compared reproducibility deviation of passive angle between healthy side and affected side with 15° test angle and 75° test angle in the observation group,there was no statistical significant difference(P＞0.05);but the reproducibility deviation of passive angle of healthy side with 15° test angle and 75°test angle in the control group were all higher than affected side,with statistical significant differences(P ＜0.05);compared the reproducibility deviation of passive angle of healthy side with 15° test angle and 75° test angle between the two groups,there was no statistical significant difference(P＞0.05);the recurrence deviation of the 15° test angle and the 75° test angle of the affected side of the observation group was lower than those of the control group,with statistical significant differences(P＜0.05).Conclusion Anterior cruciate ligament reconstruction combined with platelet rich plasma can effectively improve the postoperative posture stability and promote recovery of proprioceptive sense. 2021 Vol. 28 (17): 79-81转85 [Abstract] ( 48 ) HTML (34 KB)  PDF  (0 KB)  ( 6 ) 82 Clinical study of proximal femoral anti-rotation intramedullary nail and dynamic hip screw in the treatment of unstable intertrochanteric fracture of the femur XUE Ming; YIN Fei;LIU Hong-yan Objective To explore the clinical effect of proximal femoral anti-rotation intramedullary nail and dynamic hip screw in the treatment of unstable intertrochanteric fracture of the femur.Methods A simple random sampling method was used to enroll 80 patients with unstable intertrochanteric fractures admitted to Nankang Traditional Chinese Medicine Hospital of Ganzhou City from October 2013 to November 2020 as the research objects.They were randomly divided into the control group and the observation group by lottery,40 cases in each group,the former was treated with dynamic hip screw,and the latter was treated with proximal femoral anti-rotation intramedullary nail.The operation-related indicators,hip joint function score(Harris score),stress response level,quality of life(SF-36)score,and incidence of complications of patients between the two groups were statistically analyzed.Results The operation time and fracture healing time of the observation group were shorter than those of the control group,the total blood loss during the operation was less than that of the control group,the Harris score was higher than that of the control group,and the differences were statistically significant(P＜0.05).Before operation,there were no significant differences in the levels of angiotensin Ⅱ(Ang Ⅱ),superoxide dismutase(SOD)and SF-36 score between the two groups(P＞0.05).The Ang Ⅱand SOD levels of the observation group were lower than those of the control group,and the SF-36 score was higher than that of the control group,the differences were statistically significant(P＜0.05).The total incidence of complications in the observation group(5.00%)was lower than that in the control group(20.00%),and the difference was statistically significant(P＜0.05).Conclusion Proximal femoral anti-rotation intramedullary nails are better than dynamic hip screws for the treatment of unstable femoral intertrochanteric fractures,with less stress response and better hip function recovery,which can be preferred. 2021 Vol. 28 (17): 82-85 [Abstract] ( 54 ) HTML (34 KB)  PDF  (0 KB)  ( 7 ) 86 Application of steel plate and screw internal fixation in the treatment of traumatic fracture of long tubular bone of the extremities XIANG Jun-hua ;TAN Ping ;HU Min-juan Objective To analyze the application value of steel plate and screw internal fixation in the treatment of traumatic fracture of long tubular bones of the extremities.Methods A total of 86 patients with traumatic fracture of long bone of extremities admitted to 921 Hospital of Joint Logistic Support Force from October 2018 to June 2020 were selected as the research objects,they were divided into the control group and the observation group by the random number table method,with 43 cases in each group.The patients in the control group were treated with closed reduction and interlocking intramedullary nail internal fixation,while the observation group was treated with steel plate and screw internal fixation.The treatment effects,limb function score and visual analog scale(VAS)score before and after treatment,quality of life score,and incidence of complications were compared between the two groups.Results The overall response rate of treatment in the observation group was higher than that in the control group,the difference was statistically significant(P＜0.05).After treatment,the limb function scores of the two groups were higher than those before treatment,and the VAS scores of the two groups were lower than those before treatment,the differences were statistically significant(P＜0.05),the limb function scores of patients in the observation group were higher than those of the control group after treatment,VAS scores of patients in the observation group were lower than those of the control group after treatment,the differences were statistically significant(P＜0.05).After treatment,the scores of ability of daily living,social function,physiological function,mental health and other items in the observation group were higher than those in the control group,the differences were statistically significant(P＜0.05).The total postoperative incidence of complications of the observation group was lower than that of the control group,the difference was statistically significant(P＜0.05).Conclusion The use of steel plate and screw internal fixation in patients undergoing traumatic fracture of long tubular bone of the extremities can quickly restore the patient′s limb function,alleivate pain,improve the quality of life effectively,and the clinical treatment effect is good with few postoperative complications,which is worthy of clinical promotion and application. 2021 Vol. 28 (17): 86-88转92 [Abstract] ( 43 ) HTML (33 KB)  PDF  (0 KB)  ( 7 ) 89 Effect of percutaneous pedicle screw insertion combined with vertebroplasty on the lumbar function of patients with thoracolumbar compression fractures REN Shi-chao Objective To investigate the effect of percutaneous pedicle screw insertion combined with vertebroplasty on the lumbar function of patients with thoracolumbar compression fractures.Methods From February 2016 to February 2020,85 patients with thoracolumbar compression fractures admitted to Qingyang People′s Hospital in Gansu Province were selected as the research objects.According to the random number table method,they were divided into the control group(42 cases)and the observation group(43 cases).The control group was treated with posterior pedicle internal fixation,and the observation group was treated with percutaneous pedicle screw insertion combined with vertebroplasty.The function of the lumbar spine,the Cobb angle of the injured vertebrae,the height of the anterior and posterior edges of the vertebral body before and after the operation,the operation time,intraoperative blood loss and pain score were compared between the two groups.Results At 3 months after the operation,the Japanese Orthopaedic Association(JOA)score of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).At 3 months after the operation,the JOA scores of the two groups were higher than those before the operation,and the differences were statistically significant(P＜0.05).At 3 months after the operation,the Cobb angle of the injured vertebrae in the observation group was smaller than that in the control group,and the height of the anterior edge of the vertebral body and the height of the posterior edge of the vertebral body were higher than those in the control group,the differences were statistically significant(P＜0.05).At 3 months after the operation,the Cobb angles of the injured vertebrae of the two groups were smaller than those before the operation,and the height of the anterior edge of the vertebral body and the height of the posterior edge of the vertebral body were higher than those before the operation,the differences were statistically significant(P＜0.05).The operation time of the observation group was shorter than that of the control group,the intraoperative blood loss was less than that of the control group,and the pain score was lower than that of the control group,the differences were statistically significant(P＜0.05).Conclusion Percutaneous pedicle screw insertion combined with vertebroplasty can be used in patients with thoracolumbar compression fractures,which can improve the surgical effect,promote the improvement of the lumbar spine shape,and restore the lumbar spine function well. 2021 Vol. 28 (17): 89-92 [Abstract] ( 37 ) HTML (36 KB)  PDF  (0 KB)  ( 7 ) 93 Effect of percutaneous endoscopic discectomy in the treatment of lumbar disc herniation LI Gui-shuang;WANG Bin-cheng▲ Objective To investigate the effect of percutaneous endoscopic discectomy in the treatment of lumbar disc herniation.Methods A total of 96 patients with lumbar disc herniation in the First Affiliated Hospital of Fujian Medical University from January 2019 to December 2019 were selected as the research objects.They were randomly divided into the control group(48 cases)and the observation group(48 cases).Patients in the control group were treated with small incision interlaminar fenestration of nucleus pulposus,while patients in the observation group were treated with percutaneous transforaminal endoscopic discectomy.The operation effect,complication rate,pain score and quality of life score were compared between the two groups.Results The effective rate of postoperative clinical treatment in the observation group was 95.83%,and the effective rate of treatment in the control group was 83.33%,which was higher than that in the control group,and the difference was statistically significant(P＜0.05);the incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05);the postoperative visual analogue scale score in the observation group was lower than that in the control group,and the concise health measurement scale score was higher than the control group,the difference was statistically significant(P＜0.05).Conclusion In clinical practice,the choice of percutaneous transforaminal endoscopic discectomy has a better effect on patients with lumbar disc herniation,and can help patients reduce the probability of complications,which is worthy of promotion. 2021 Vol. 28 (17): 93-95转99 [Abstract] ( 41 ) HTML (35 KB)  PDF  (0 KB)  ( 8 ) 96 Effect of lumbar traction combined with physical therapy in the treatment of lumbar disc herniation YAN Fang-fang Objective To observe the effect of lumbar traction combined with physical therapy in the treatment of lumbar disc herniation(LDH).Methods A total of 68 patients with LDH admitted to Zhenjiang Ruikang Hospital from March to July 2020 were enrolled as the research objects.They were divided into the treatment group and the control group by random double-blind method,with 34 cases in each group.Patients in the control group only received lumbar traction,and patients in the treatment group were treated with physical therapy on the basis of the control group.The clinical efficacy,pain improvement,straight leg elevation angle and lumbar function recovery of the two groups were observed.Results After treatment,the total clinical effective rate of the treatment group and the control group was 94.12% and 70.59%,respectively.The total clinical effective rate of the treatment group was higher than that of the control group,and the difference was statistically significant(P＜0.05).Before treatment,there were no statistically significant differences in the visual analogue scale(VAS),emotional pain rating index(emotional PRI),and sensory PRI scores between the two groups(P＞0.05).After treatment,the scores of VAS,emotional PRI,and sensory PRI in the treatment group were lower than those of the same group before treatment and in the control group,and the differences were statistically significant(P＜0.05).Before treatment,there were no significant differences in the straight leg elevation angle and Oswestry disability index(ODI)score between the two groups(P＞0.05).After treatment,the straight leg elevation angle in the treatment group was higher than that of the same group before treatment and in the control group,and the ODI score was lower than that of the same group before treatment and in the control group,the differences were statistically significant(P＜0.05).Conclusion Lumbar traction combined with physical therapy can significantly improve the clinical efficacy of LDH patients,relieve their pain,improve lumbar spine function and lower limb dysfunction,and provide a new theoretical basis for clinical treatment of LDH. 2021 Vol. 28 (17): 96-99 [Abstract] ( 41 ) HTML (37 KB)  PDF  (0 KB)  ( 7 ) 100 Effect and safety analysis of Amlotinib on lung function in patients with non-small cell lung cancer CHU Jie-sheng; XU Guan-jun; SHI Yu ;DING Zhi ;FU Jing-zhong▲ Objective To investigate the effect and safety of Amlotinib on lung function in patients with non-small cell lung cancer.Methods A total of 48 patients with non-small cell lung cancer treated in the Jiujiang Third People′s Hospital from December 2018 to December 2019 were selected as the research objects,and divided into the observation group(24 cases)and the control group(24 cases)by random number table method.The control group was treated with Paclitaxel Albumin combined with Cisplatin chemotherapy,and the observation group was treated with Amrotinib on the basis of control group.The therapeutic effect,lung function and the incidence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 91.67%,which was higher than that of the control group(75.07%),and the difference was statistically significant(P＜0.05).Before treatment,there were no significant differences in forced vital capacity(FVC),forced expiratory volume in the first second(FEV1)and FEV1/FVC between the two groups(P＞0.05).After treatment,the levels of FVC,FEV1 and FEV1/FVC in the two groups were higher than before,and the levels of FVC,FEV1 and FEV1/FVC in the observation group were higher than those in the control group,with statistical significances(P＜0.05).The total incidence of adverse reactions in the observation group was 9.10%,which was lower than that in the control group(25.00%),and the difference was statistically significant(P＜0.05).Conclusion Anlotinib in the treatment of non-small cell carcinoma can effectively improve the lung function of patients,control tumor progression,and promote the recovery of the disease,with high safety. 2021 Vol. 28 (17): 100-102 [Abstract] ( 55 ) HTML (33 KB)  PDF  (0 KB)  ( 7 ) 103 Influence of high-dose Gemcitabine intravesical infusion chemotherapy on the recurrence and adverse reactions of non-muscular invasive urothelial carcinoma of the bladder WAN Bin; ZHANG Wen-sheng ;DENG Xin-xi; LI Xun-gang Objective To explore the influence of high-dose Gemcitabine intravesical infusion chemotherapy on the recurrence and adverse reactions of non-muscular invasive urothelial carcinoma of the bladder.Methods A total of 30 patients with non-muscular invasive urothelial carcinoma of the bladder who were admitted to the First People′s Hospital of Jiujiang City from July 2018 to June 2019 were selected as the research objects.According to the random number table method,they were divided into the control group(15 cases)and the study group(15 cases).The control group used regular dose Gemcitabine bladder perfusion local chemotherapy,and the study group used high-dose Gemcitabine intravesical infusion chemotherapy.The recurrence rate,recurrence time,and the total incidence rate of adverse reaction of the two groups were compared.Results The recurrence rate of the study group was lower than that of the control group,and the recurrence time of the study group was longer than that of the control group,the difference was statistically significant(P＜0.05).There was no statistically significant difference in the total incidence rate of adverse reaction between the two groups(P＞0.05).Conclusion High-dose Gemcitabine intravesical infusion chemotherapy for non-muscular invasive urothelial carcinoma of the bladder can reduce the recurrence rate and prolong the recurrence time to a certain extent,and have no significant increase in adverse reactions. 2021 Vol. 28 (17): 103-105 [Abstract] ( 43 ) HTML (31 KB)  PDF  (0 KB)  ( 6 ) 106 Clinical effect of Albumin-bound Paclitaxel in the treatment of recurrent advanced non-small cell lung cancer HOU Juan ;CUI Li-hua; WU Zhi-wei; HUANG Yu-feng ;MA De Objective To investigate the clinical effect of Albumin-bound Paclitaxel in the treatment of recurrent advanced non-small cell lung cancer.Methods A total of 40 patients with recurrent advanced non-small cell lung cancer treated in Jingjiang People′s Hospital from February 2018 to August 2020 were selected as the research subjects and divided into the study group(20 cases)and the control group(20 cases)according to random number table method.The control group received conventional Paclitaxel chemotherapy regimen,and the study group received Albumin-bound Paclitaxel treatment.The total effective rate,total incidence of adverse reactions and quality of life scores of two groups were compared.Results The total effective rate of the study group was higher than that of the control group,and the difference was statistically significant(P＜0.05).The incidence of adverse reactions in the study group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Before treatment,there was no significant difference in quality of life scores between the two groups(P＞0.05).After treatment,the quality of life scores of the two groups were higher than before treatment,and the study group was higher than the control group,the differences were statistically significant(P＜0.05).Conclusion Treatment with Albumin-bound Paclitaxel in patients with recurrent advanced non-small cell lung cancer has a better effect,which can improve clinical symptoms and quality of life,and has a higher safety,which is worthy of clinical promotion. 2021 Vol. 28 (17): 106-108 [Abstract] ( 46 ) HTML (32 KB)  PDF  (0 KB)  ( 8 ) 109 Clinical effect of Trastuzumab targeting in the treatment of breast cancer BI Da-peng Objective To explore the clinical effect of Trastuzumab targeting in the treatment of breast cancer patients.Methods A total of 100 cases of breast cancer patients admitted to Anshan Cancer Hospital from December 2017 to December 2019 were selected selected as the research objects,and they were randomly divided into the control group(n=50)and the observation group(n=50)using computers.The control group was only treated with conventional chemotherapy,while the observation group was treated with Trastuzumab targeting treatment on the basis of the control group.The treatment effect,adverse drug reactions and the total incidence of complications of the two groups were compared.Results The total effective rate of patients in the observation group was higher than that in the control group，and the difference was statistically significant(P＜0.05).There was no significant difference in the incidence of adverse drug reactions between the two groups(P＞0.05).The incidence of complications in the observation group was lower than that in the control group，and the difference was statistically significant(P＜0.05).Conclusion Trastuzumab targeted treatment of breast cancer patients has significant effect,can effectively improve the treatment effect,reduce the occurrence of complications,and less adverse drug reactions,high safety,it is worthy of promotion and application. 2021 Vol. 28 (17): 109-111 [Abstract] ( 52 ) HTML (31 KB)  PDF  (0 KB)  ( 5 ) 112 Application effect of three-dimensional visualization of fallopian tube in minimally invasive surgery for infertility CHEN Lin ;CHEN Gui-zhen ;HUANG Chun; WANG Wen-hua ;ZHANG Fu-yun Objective To investigate the effect of three-dimensional visualization of fallopian tube in minimally invasive surgery for infertility.Methods A total of 42 infertile women with fallopian tube block treated in Jiangxi Pingxiang People′s Hospital from August 2017 to August 2018 were selected as the research subjects.According to the random number table method,they were divided into study group(21 cases)and control group(21 cases).The control group was treated with traditional hysteroscopy for infertility combined with laparoscopic minimally invasive surgery,and the study group was given hysteroscopy for infertility combined with minimally invasive surgery with the aid of three-dimensional visualization of fallopian tube.The surgical time,intraoperative blood loss,time of vaginal bleeding stop and recurrence rate of fallopian tube block at 3 months after surgery,total incidence rate of complications within 3 months after surgery,pregnancy rate within 1 year after surgery and delivery success rate within 2 years after surgery were compared between the two groups.Results The intraoperative blood loss and total incidence rate of complications within 3 months after surgery in the study group were lower than those in the control group,the surgical time and vaginal bleedin stop time in the study group was chorter than those in the control group,with statistical significance(P＜0.05).The recurrence rate of fallopian tube block at 3 months after surgery in study group was lower than that in control group,the difference was statistically significant(P＜0.05).The pregnancy rate in 1 year and successful delivery rate in 2 years in the study group were higher than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion The application of tubal three-dimensional visualization technology in infertility microtrauma can significantly improve the surgical effect,improve the reproductive function of patients which is suitable for clinical application. 2021 Vol. 28 (17): 112-114 [Abstract] ( 43 ) HTML (32 KB)  PDF  (0 KB)  ( 6 ) 115 Effect of uterine artery embolization combined with Methotrexate in the treatment of cesarean scar pregnancy on the level of β-chorionic gonadotropin XI Yan-dong; BAI Hong Objective To explore the therapeutic value of uterine artery embolization(UAE)combined with Methotrexate on cesarean scar pregnancy(CSP)and the effect on the level human of β-chorionic gonadotropin(β-hCG).Methods A total of 122 cases CSP patients admitted to the the First People′s Hospital of Yinchuanfron January 2018 to April 2020 were selected as the research objects,they were classified into the combined group and the drug group according to the random number table method,each group had 61 cases,the drug group was treated with Methotrexate,combined group UAE combined with Methotrexate treatment.β-hCG level,operative indexes and complications of the two groups were observed.Results Before treatment,the β-hCG levels of the two groups of patients were not statistically different(P＞0.05);after treatment,the β-hCG levels of the two groups of patients were lower than those before treatment,and the β-hCG levels of the combination group were low than those in the drug group,the differences were statistically significant(P＜0.05).The operation time and hospital stay of the combined group were shorter than those of the drug group,and the intraoperative blood loss was less than that of the drug group，the differences were statistically significant(P＜0.05).The total incidence of complications in the combined group was lower than that in the drug group,the difference was statistically significant(P＜0.05).Conclusion UAE combined with methotrexate has a clear effect on CSP.It can shorten the operation time,hospital stay,reduce intraoperative blood loss,and reduce the level of gonadal hormones,with fewer complications,and is clinically safe and feasible. 2021 Vol. 28 (17): 115-117转121 [Abstract] ( 40 ) HTML (34 KB)  PDF  (0 KB)  ( 7 ) 118 Effect of early pelvic floor rehabilitation device training plus biofeedback electrical stimulation therapy on serum leptin level and muscle strength in patients with postpartum pelvic floor dysfunction YANG Fan ;ZHAO Qi ;LUO Quan ;SONG Yan-hui ;YANG La-zhi ;CHENG Xian ;YUAN Xiao-hong ;LYU Jun Objective To study and explore the effect of early pelvic floor rehabilitation device training and biofeedback electrical stimulation therapy on serum leptin level in patients with postpartum pelvic floor muscle dysfunction.Methods A total of 80 patients with postpartum pelvic floor dysfunction in Jiujiang Maternal and Child Health Hospital of Jiangxi Province from January 2018 to January 2020 were selected as the research subjects,and they were divided into study group(n=40)and control group(n=40)according to the random number table method.Study group was given early pelvic floor rehabilitation device training combined with biofeedback electrical stimulation therapy,and control group was treated with early pelvic floor rehabilitation device training.The muscle strength classification,serum leptin level and total effective rate of treatment were compared between the two groups before and after treatment.Results The total effective rate of the study group was 95.00%,which was higher than that of the control group(80.00%),and the difference was statistically significant(P＜0.05).Before treatment,there was no significant difference in serum leptin between the two groups(P＞0.05).At 1,2 and 3 months after treatment,the serum leptin levels in the study group were lower than those in the control group,and the differences were statistically significant(P＜0.05).Before treatment,there was no statistical significance in muscle strength grading between the two groups(P＞0.05).After treatment,the muscle strength grading in the study group was better than that in the control group,the difference was statistically significant(P＜0.05).Conclusion Early pelvic floor rehabilitation device training combined with biofeedback electrical stimulation can improve the pelvic floor muscle strength of patients with postpartum pelvic floor muscle dysfunction,reduce serum leptin level,and improve treatment efficiency. 2021 Vol. 28 (17): 118-121 [Abstract] ( 29 ) HTML (34 KB)  PDF  (0 KB)  ( 6 ) 122 Efficacy comparison of four adjustment cycles after hemostasis in adolescent abnormal uterine bleeding-ovulatory disorders LIU Wei ;JIANG Zhuang-liang ;DU Xiao-han Objective To compare the efficacy of four adjustment cycle programs after hemostasis in adolescent abnormal uterine bleeding-ovulatory disorders(AUB-O).Methods A total of 100 adolescent AUB-O patients who were admitted to the Outpatient and Inpatient Department of Jiangxi Maternity and Child Health Hospital from June 2016 to June 2018 were selected.They were divided into four groups by a random number table method,with 25 cases in each group.Progesterone regimen was used in group A;artificial cycle at a low-dose estrogen regimen was used in group B;artificial cycle in a routine estrogen regimen was used in group C;contraceptive regimen of Ethinyl Estradiol and Cyproterone Tablets was adopted in group D.All of these interventions were treated continuously for three cycles and followed up for six months.The clinical efficacy of the four groups after treatment,the incidence of adverse reactions during treatment,the biphasic rate of basal body temperature(BBT)and the recurrence rate at the end of follow-up were compared.Results After three cycles of treatment,the total effective rate of treatment in group D was higher than that of group A,B,and C,with statistical significance(P＜0.05).There was no significant difference in total effective rate of treatment among group A,B,and C(P＞0.05).There was no significant difference in the occurrence of adverse reactions among the four groups(P＞0.05).After six months of follow-up,the biphasic rate of BBT in group D was higher than that of group A,B,and C,with statistical significance(P＜0.05).There was no significant difference in the biphasic rate of BBT in group A,B,and C(P＞0.05).The recurrence rate of group D was lower than that of group A,B,and C,with statistical significance(P＜0.05).On regard of the recurrence rate,there was no significant difference among group A,B,and C(P＞0.05).Conclusion Oral administration of Ethinyl Estradiol and Cyproterone Tablets can increase the biphasic rate of BBT in adolescent AUB-O patients,reduce the recurrence rate,without significant increase of the incidence of adverse reactions.The safety and effectiveness of the treatment are good. 2021 Vol. 28 (17): 122-125 [Abstract] ( 41 ) HTML (36 KB)  PDF  (0 KB)  ( 6 ) 126 Delivery of in vitro fertilization-embryonic transplantation assisted conception and natural conception and neonatal outcomes analysis SUN Xiao-yan; YANG Chang-yu Objective To investigate the birth of in vitro fertilization-embryonic transplantation(IVF-ET)assisted conception and natural conception and neonatal conditions.Methods A retrospective analysis was conducted on 8318 puerperae′s clinical data and delivery of newborns from January 2019 to December 2019 in our hospital.According to different conceptions,they were divided into a test tube group(523 cases of pregnant women,611 cases of neonates)and a normal group(7795 cases of pregnant women,7911 cases of neonates).The mode of delivery,complications associated with delivery,and neonatal outcomes were compared in the two groups.Results The incidence of cesarean section of the test tube group was higher than that in the normal group,and the difference was statistically significant(P＜0.05).The incidence rates of premature birth,placenta previa,postpartum bleeding,and eclampsia in the test tube group were higher than those of the normal group,the differences were statistically significant(P＜0.05).There were no statistically significant differences in the incidence rates of dystocia or premature rupture of fetal membranes between the two groups(P＞0.05).The incidence rates of neonatal infectious pneumonia and low birth weight were higher than those of the normal group with statistical significance(P＜0.05).Conclusion The risks of delivery-related complications and neonatal complications are increased in IVF-ET assisted conception,which increases the probability of cesarean section,should pay attention to perinatal care,and treat complications in time. 2021 Vol. 28 (17): 126-128转132 [Abstract] ( 34 ) HTML (34 KB)  PDF  (0 KB)  ( 6 ) 129 Application of standardized diet intervention on improving children with food allergy WEI Shu-fei;WANG Xing-ling; LI Xiao-yu;LAN Hai-yan; CHEN Shao-jun Objective To observe the curative effect of standardized diet intervention to improve food allergy(FA)children.Methods A total of 90 cases of FA children admitted to the Second People′s Hospital of Zhaoqing from May to October 2019 were selected as the research objects.They were divided into experimental group(45 cases)and control group(45 cases)by random number table method.The experimental group was given standardized diet nutrition intervention,and the control group was given conventional diet.Both groups were followed up for 9 months.The effect of improving the clinical symptoms of FA was compared between the two groups,and the changes of height,weight and hemoglobin of children after different dietary interventions were compared.Results After 9 months of follow-up,the total effective rate of FA in the experimental group was higher than that in the control group,and the difference was statistically significant(P＜0.05).The height,weight and hemoglobin of the experimental group were higher than those of the control group,and the differences were statistically significant(P＜0.05).Conclusion Standardized dietary intervention can improve the clinical symptoms and nutritional status of children with food allergy,which has obvious curative effect and is worthy of promotion. 2021 Vol. 28 (17): 129-132 [Abstract] ( 48 ) HTML (34 KB)  PDF  (0 KB)  ( 7 ) 133 Clinical effect of Ex-Press drainage nail implantation in the treatment of neovascularization glaucoma HUANG Hai；ZHENG Wei▲ Objective To investigate the clinical effect of Ex-Press drainage nail implantation in the treatment of neovascularization glaucoma(NVG).Methods A total of 60 patients with NVG admitted to the Affiliated Hospital of Guilin Medical College from January 2015 to June 2019 were selected as the research objects for retrospective analysis and divided into the observation group(30 cases)and the control group(30 cases)according to anti-glaucoma surgery methods.Before anti-glaucoma surgery,both groups received intravitreous injection of Conbercept.After iris neovascularization subsided,the observation group received Ex-Press aqueous chamber drainage screw implantation,while the control group received compound trabeculectomy.According to the regression of neovascularization,total retinal photocoagulation was performed 2-3 weeks after surgery in both groups.The intraocular pressure at 3 d,1 week and 1,3,6,12 months after anti-glaucoma surgery,the visual acuity at 12 months after surgery,the total effective rate of surgery and the incidence of complications were compared between two groups.Results There was no significant difference in intraocular pressure between the two groups before operation(P＞0.05).The intraocular pressures at 3 d,1 week,1,3,6 and 12 months after surgery in both groups were lower than those before surgery,and the intraocular pressures in the observation group were lower than those in the control group at each time point after surgery,the differences were statistically significant(P＜0.05).There was no significant difference in best corrected visual acuity(BCVA)between the two groups(P＞0.05).At 12 months after operation,BCVA in the observation group was better than that in the control group,and the difference was statistically significant(P＜0.05).The total incidence of complications in the observation group was lower than that in the control group,and the total operative effective rate was higher than that in the control group,with statistical significances(P＜0.05).Conclusion Conbercept combined with total retinal photocoagulation combined with Ex-Press aqueous chamber drainage nail implantation in the treatment of NVG has been shown to effectively reduce intraocular pressure and improve visual acuity,with significant results and fewer complications. 2021 Vol. 28 (17): 133-136 [Abstract] ( 41 ) HTML (40 KB)  PDF  (0 KB)  ( 7 ) 137 Observation on the curative effect of laser combined with Ranibizumab in the treatment of proliferative diabetic retinopathy LIU Tao ;ZENG Zhi ;LI Shu-ming Objective To investigate the clinical effect of laser combined with Ranibizumab in the treatment of proliferative diabetic retinopathy.Methods A total of 110 patients with proliferative diabetic retinopathy admitted to Meizhou Hospital of Traditional Chinese Medicine from November 2018 to November 2019 were selected as the research subjects,and divided into the control group(55 cases)and the research group(55 cases)according to random number table method.The control group was given laser treatment,and the research group was given Ranibizumab treatment on the basis of the control group.The effect of treatment and the changes of retinal thickness before and after treatment were compared.Results The total effective rate of the study group was 96.4%,which was higher than that of the control group(81.8%),and the difference was statistically significant(P＜0.05).Before treatment,there was no significant difference in retinal thickness between two groups(P＞0.05).On day 30 and 90 after treatment,the retinal thickness of the two groups was lower than that before treatment,and the retinal thickness of the study group was lower than that of the control group,the differences were statistically significant(P＜0.05).Conclusion The application of laser combined with Ranibizumab in the treatment of proliferative diabetic retinopathy has significant effects,which can effectively improve patients′ visual acuity,reduce retinal thickness,stabilize retinal blood vessels,and promote the improvement of patients′ quality of life,and is worthy of clinical promotion. 2021 Vol. 28 (17): 137-139 [Abstract] ( 50 ) HTML (31 KB)  PDF  (0 KB)  ( 6 ) 140 Application effect of local anesthesia with Lidocaine combined with Midazolam sedation in patients undergoing tracheoscopic examination XU Jun-lian ;QIU Su-ping Objective To investigate the application effect of local anesthesia with Lidocaine combined with Midazolam sedation in patients undergoing tracheoscopic examination.Methods A total of 60 patients undergoing bronchoscopy in the Fifth People′s Hospital of Ganzhou City from January 2017 to December 2018 were selected as study subjects,and were divided into the reference group and the study group according to the random throwing method,with 30 cases in each group.The reference group was administered with Lidocaine local anesthesia,and the study group was sedated with Midazolam and Fentanyl on the basis of the reference group.The examination related conditions,physiological indexes at each moment,the total incidence of adverse events and patient satisfaction were compared between the two groups.Results There was no significant difference in the time of full wakefulness between the two groups(P＞0.05).The operation time of the study group was shorter than that of the reference group,and the visual analogue scale(VAS)score was lower than that of the reference group,and the differences were statistically significant(P＜0.05).The mean arterial pressure(MAP),heart rate(HR)and respiratory rate(RR)at T1,T2 and T3 in control group were higher than T0,and the blood oxygen saturation(SpO2)level was lower than T0,and the differences were statistically significant(P＜0.05).In the study group,MAP and HR at moments T1,T2 and T3 were higher than those at moment T0,SpO2 level was lower than that at moment T0,and RR at moments T1 and T3 were higher than those at moment T0,and the differences were statistically significant(P＜0.05).The MAP,HR and RR at T1,T2 and T3 in the study group were lower than those in the control group,and the SpO2 level was higher than that in the control group,and the differences were statistically significant(P＜0.05).The incidence of adverse events in the study group(6.67%)was lower than that in the control group(26.67%),and the difference was statistically significant(P＜0.05).The total satisfaction of the study group(96.67%)was higher than that of the control group(80.00%),and the difference was statistically significant(P＜0.05).Conclusion Local anesthesia combined with Midazole sedation has a significant effect on patients undergoing tracheal examination.It can maintain the stability of patients′ signs and reduce the risk of related adverse events,with high safety. 2021 Vol. 28 (17): 140-143 [Abstract] ( 41 ) HTML (41 KB)  PDF  (0 KB)  ( 6 ) 144 Effect of Dexamethasone combined with Ropivacaine erectorspinae plane block in lumbar interbody fusion LIAO Qi ;ZENG Fan-ying ;YE Li-qin ;LAI Jian-hong Objective To observe the effect of Dexamethasone combined with Ropivacaine erectorspinae plane block(ESPB)for posterior lumbar interbody fusion(PLIF).Methods A total of 60 patients with elective PLIF surgery treated in Ganzhou Traditional Chinese Medicine Hospital from September 2019 to October 2020 were selected as the research subjects,and were divided into an experimental group(n=30)and a control group(n=30)by the random number table method.The control group was given general anesthesia,and the experimental group was combined Dexamethasone with Ropivacaine ESPB on this basis.The total intraoperative dose of Cisatracurium,the total intraoperative dose of Sufentanil,the number of postoperative intravenous analgestic pump(PCIA)press and the visual analogue scale(VAS)of pain scores at different time(4,8,12,24 and 48 h after surgery)were compared between the two groups.Results The total intraoperative dose of Cisatracurium,the total intraoperative dose of Sufentanil and the number of PCIA press after operation in experimental group were lower than those in control group,with statistically significant differences(P＜0.05).There were statistically significant differences between the two groups in terms of intergroup,time point and interaction(P＜0.05).VAS scores at 8,12,24 and 48 h after surgery in the two groups were higher than those at 4 h after surgery,with statistically significant differences(P＜0.05).VAS scores of experimental group at 4,8,12,24 and 48 h after surgery were all lower than those of control group,with statistically significant differences(P＜0.05).Conclusion Dexamethasone combined with Ropivacaine ESPB for PLIF surgery can reduce the dosage of sedative and analgesic drugs and muscle relaxants,and reduce postoperative pain in patients.It is worthy of clinical promotion. 2021 Vol. 28 (17): 144-147 [Abstract] ( 44 ) HTML (35 KB)  PDF  (0 KB)  ( 8 ) 148 Application of Remifentanil combined with Propofol anesthesia in laparoscopic cholecystectomy for acute cholecystitis REN Nan-nan Objective To study the clinical effect of Remifentanil combined with Propofol anesthesia in patients undergoing laparoscopic cholecystectomy for acute cholecystitis and its influence on hemodynamic indexes.Methods A total of 124 patients with acute cholecystitis who received laparoscopic cholecystectomy in the Affiliated Central Hospital of Shenyang Medical College from June 2017 to June 2019 were selected as the research objects and divided into the observation group and the control group by random number table method,with 62 cases in each group.Patients in the control group received Remifentanil anesthesia while patients in the observation group received Remifentanil combined with Propofol anesthesia Anesthesia effect,anesthesia quality(sedation score[Ramsay score],motor nerve block score[Bromage score],awakening score[Steward score],visual analogue scale[VAS]score)and hemodynamic indexes(heart rate[HR],systolic blood pressure[SBP],diastolic blood pressure[DBP],left ventricular ejection fraction[LVEF],left ventricular end-diastolic blood pressure[LVEDd])were compared between the two groups.Results The excellent and good rate of anesthesia effect in the observation group(93.55%)was higher than that in the control group(83.87%),and the difference was statistically significant(P＜0.05).The Ramsay score,Bromage score and Steward score of the observation group were higher than those of the control group,and the VAS score was lower than that of the control group,the differences were statistically significant(P＜0.05).Before anesthesia induction,there were no statistically significant differences in hemodynamic indexes between the two groups(P＞0.05).After anesthesia induction,SBP,LVEF and LVEDd in observation group were lower than those before induction,HR,SBP,DBP,LVEF and LVEDd in control group were lower than those before anesthesia induction,and the differences were statistically significant(P＜0.05).After anesthesia,HR,SBP,DBP,LVEF and LVEDd of the two groups were lower than those before anesthesia induction,and the differences were statistically significant(P＜0.05).After operation,SBP,DBP and LVEDd in the observation group were lower than those before anesthesia induction,HR in the control group was higher than that before anesthesia induction,SBP,DBP,LVEF and LVEDd in the control group were lower than those before induction,and the differences were statistically significant(P＜0.05).After anesthesia induction and implementation,HR,SBP,DBP,LVEF and LVEDd in observation group were higher than those in control group,and the differences were statistically significant(P＜0.05).After surgery,SBP,DBP,LVEF and LVEDd in observation group were higher than those in control group,HR in observation group was lower than that in control group,and the difference was statistically significant(P＜0.05).Conclusion Remifentanil combined with Propofol anesthesia in the treatment of acute cholecystitis in laparoscopic cholecystectomy has good anesthetic effect,good quality of anesthesia for patients,postoperative recovery is also good,and the degree of hemodynamic changes in patients is smaller,the patient′s vital signs are more stable,and the safety is higher. 2021 Vol. 28 (17): 148-151 [Abstract] ( 42 ) HTML (38 KB)  PDF  (0 KB)  ( 7 ) 152 Safety analysis of Ticagrelor as an adjuvant medication for patients with acute coronary syndrome after percutaneous coronary intervention ZHAO Zuan-hua;TAN Jia-jin; TAN Shun-pei Objective To analyze the safety of Ticagrelor as an adjuvant therapy for patients with acute coronary syndrome(ACS)after percutaneous coronary intervention(PCI).Methods From March 2018 to May 2020,60 ACS patients in Taishan People′s Hospital were selected as research subjects.According to the random number table method,they were divided into the control group and the study group,with 30 cases in each group.PCI was implemented according to China PCI Treatment Guideline 2012(concise).Patients after admission in the two groups were given load dose/conventional dose of Aspirin after PCI.In the control group,the load dose/conventional dose of Clopidogrel in oral administration after PCI was used;in the study group,oral administration of Ticagrelor at a load dose/conventional dose was added after PCI.The adverse cerebrovascular events,bleeding events,and adverse reactions were compared between the two groups within six months after surgery.Results There was no significant difference in the incidence of adverse cerebrovascular events after surgery in the two groups(P＞0.05).The incidence of postoperative bleeding events after surgery was lower than that of the control group,the difference was statistically significant(P＜0.05).The incidence of postoperative adverse reactions in the study group was lower than that of the control group,the difference was statistically significant(P＜0.05).Conclusion Ticagrelor has more advantages than Clopidogrel in reducing the incidence of adverse events and adverse reactions in patients with ACS,which is worthy of clinical promotion and application. 2021 Vol. 28 (17): 152-154转158 [Abstract] ( 43 ) HTML (34 KB)  PDF  (0 KB)  ( 9 ) 155 Clinical effect of Ivabradine Tablets combined with Atorvastatin Calcium Tablets in the treatment of patients with carotid atherosclerosis JIANG Ren-gui ;ZENG Xiang-hui ;ZHAO Li-li ;ZHANG Bi-long Objective To explore the clinical effect of Ivabradine Tablets combined with Atorvastatin Calcium Tablets in the treatment of patients with carotid atherosclerosis.Methods A total of 84 patients with carotid atherosclerosis admitted to Ganzhou Municipal Hospital from June 2018 to March 2020 were selected as the research objects,and were divided into control group(n=40)and observation group(n=44).The control group was treated with Atorvastatin Calcium Tablets,and the observation group was treated with Ivabradine Tablets combined with Atorvastatin Calcium Tablets.The changes in blood lipid metabolism,inflammation and oxidative stress levels were compared between the two groups.Results After six months of treatment,the total cholesterol(TC),triacylglycerol(TG),low density lipoprotein cholesterin(LDL-C),high density lipoprotein cholesterol(HDL-C)concentration,high sensitivity C-reactive protein(hs-CRP),oxidized low density lipoprotein(ox-LDL)and oxidative stress marker malondialdehyde(MDA)levels of the observation group were lower than those of the control group,and the superoxide dismutase(SOD)level was higher than that of the control group,the differences were statistically significant(P＜0.05).After half a year of treatment,the medial intima thickness(IMT)in the observation group was lower than that of the control group,with statistical difference(P＜0.05).Conclusion Ivabradine Tablets combined with Atorvastatin Calcium Tablets has a prominent effect on blood lipid metabolism,inflammation and oxidative stress in patients with carotid atherosclerosis.It obtains a significant antiatherosclerosis effect and is beneficial to the prevention of cardiovascular and cerebrovascular events. 2021 Vol. 28 (17): 155-158 [Abstract] ( 61 ) HTML (35 KB)  PDF  (0 KB)  ( 6 ) 159 Effect of Rabeprazole-based triple therapy in the treatment of peptic ulcer disease ZHAO Xin-chen Objective To investigate the effect of Rabeprazole-based triple therapy in the treatment of peptic ulcer disease.Methods A total of 80 patients with peptic ulcer disease admitted to Tianjin Fourth Central Hospital from January 2017 to January 2019 were selected as research objects,and they were divided into the Omeprazole group(40 cases)and the Rabeprazole group(40 cases)according to the random number table method.The Omeprazole group was treated with Omeprazole triple therapy,the Rabeprazole group was treated with Rabeprazole triple therapy.The efficacy and safety of the two methods were analyzed.Results The total effective rate of the Rabeprazole group was higher than that of the Omeprazole group,with statistically significant difference(P＜0.05).While the clinical symptom score,the levels of serum interleukin-6,C-reactive protein,and tumor necrosis factor-α levels of the Rabeprazole group were lower than those of the Omeprazole group,with statistically significant difference(P＜0.05).There was no significant difference in the total incidence of adverse reactions after treatment between the two groups(P＞0.05).Conclusion Rabeprazole-based triple therapy in the treatment of peptic ulcer disease has better therapeutic effect,can improve clinical symptom,reduce serum interleukin-6,C-reactive protein,and tumor necrosis factor-α levels.It is worthy of clinical promotion. 2021 Vol. 28 (17): 159-161 [Abstract] ( 36 ) HTML (32 KB)  PDF  (0 KB)  ( 7 ) 162 Clinical effect of Rivaroxaban and Low Molecular Weight Heparin Sodium in the treatment of portal vein thrombosis WAN Dong-qiang; WANG Huo-ping ;HU Hai-yang ;HU Wen-feng Objective To explore the effect of Rivaroxaban and Low Molecular Weight Heparin Sodium in the treatment of portal vein thrombosis.Methods A total of 72 patients with portal vein thrombosis who received treatment in the General Surgery Department of the Third People′s Hospital of Jiujiang City from June 2019 to June 2020 were selected as the research subjects.They were divided into group A(oral administration of Rivaroxaban at 72 hours before surgery),group B(oral administration of Rivaroxaban at 72 hours after surgery),and group C(subcutaneous injection of Low Molecular Weight Heparin Sodium at 72 hours after surgery)by random number table method,with 24 patients in each group.After treatment,the total incidence of adverse events,indicators related to portal vein recanalization and the total incidence of thrombus events of the three groups were compared.Results After treatment,the total incidence of adverse events in group A was higher than that in group B and C,with statistical significance(P＜0.05).There was no significant difference in the total incidence of adverse events between group B and group C(P＞0.05).After treatment,D-dimer were lower than those in group B and C,prothrombin time(PT)and activated partial prothrombin time(APTT)in group A were shorter than those in group B and C,and fibrinogen(FIB)value was higher than that in group B and C,the differences were statistically significant(P＜0.05).After treatment,there was no significant difference in INR value among group A,B and C(P＞0.05).There were no significant differences in D-dimer,PT,APTT and INR values between group B and C(P＞0.05).After treatment,the total incidence of thrombus events in group A was lower than that in group B and C,with statistical significance(P＜0.05).There was no significant difference in the total incidence of thrombus events between group B and group C(P＞0.05).Conclusion In the process of clinical treatment of portal vein thrombosis,there was no significant difference in the anticoagulant effect of patients treated with Rivaroxaban or Low Molecular Weight Heparin Sodium at 72 h after operation.However,patients treated with Rivaroxaban at 72 h before surgery was helpful to reduce the incidence of thrombus in patients.There was no significant difference in the incidence of thrombosis among patients treated with Rivaroxaban or Low Molecular Weight Heparin Sodium at 72 h before surgery.On the other hand,patients treated with Rivaroxaban at 72 h before surgery was more helpful for portal vein recanalization. 2021 Vol. 28 (17): 162-165 [Abstract] ( 42 ) HTML (38 KB)  PDF  (0 KB)  ( 7 ) 166 State medical master ZHOU Yu-zhu′s experience in treating breast disease MA Hui ;YI Wei-zhen ;ZHOU Yu-zhu; TANG Lei-lei ;ZHANG Jing ;HUI Xin-yuan; SUI Ying Professor ZHOU Yu-zhu is a national-level veteran traditional Chinese medicine doctor in The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine.He is good at preventing and treating various diseases with Chinese medicine.He is particularly experienced in the diagnosis and treatment of breast diseases.Professor Zhou Yu-zhu summed up many years of clinical experience and created the basic prescription for the treatment of breast diseases,namely Heru Decoction.In actual application,it is modified according to the principle of syndrome differentiation and treatment,and it has become a widely used empirical formula inbreast surgery in our department.This article shares the three classic cases of Professor ZHOU′s clinical diagnosis and treatment.The three types of breast diseases are treated with Xingqi Heru Decoction,Huayu Heru Decoction,Qingre Heru Decoction,to learn and explore Chinese medicine in the treatment of breast disease advantages in aspects and the experience and insights of Chinese medicine practitioners on breast diseases. 2021 Vol. 28 (17): 166-168转172 [Abstract] ( 55 ) HTML (31 KB)  PDF  (0 KB)  ( 6 ) 169 Chief physician Yang Ruilong′s experience in body differentiation and treatment of migraine in remission period NIU Ting-ting;YANG Rui-long;ZHONG Xing Migraine is a common clinical primary headache,and its treatment focuses on prevention,and preventive treatment in remission is particularly important.Body differentiation therapy makes up for the unidentifiable condition of migraine in the remission period.It is a treatment method that achieves the purpose of curing diseases by changing physical bias.This diagnosis and treatment method is in line with the principles of migraine treatment.Chinese and Western medicine diagnosis and treatment programs have great advantages.This paper discusses the importance of body differentiation in the diagnosis and treatment of migraine in remission period,and analyzes the case of Dr.Yang Ruilong′s body differentiation in the treatment of migraine in remission period,in order to provide reference for the selection of prevention and treatment programs for clinical migraine in remission period. 2021 Vol. 28 (17): 169-172 [Abstract] ( 42 ) HTML (36 KB)  PDF  (0 KB)  ( 6 ) 173 Effect of Zhitong Rushen Decoction modified fumigation in the treatment of hemorrhoid patients CHEN Xiao-cui; JIANG Ming-ying Objective To investigate the effect of Zhitong Rushen Decoction modified fumigation in the treatment of hemorrhoid patients.Methods A total of 66 patients with hemorrhoids in Wuyishan Municipal Hospital from September 2017 to September 2019 were selected as the research objects,and they were divided into the control group(33 cases)and the observation group(33 cases)according to dynamic random grouping method.The control group was treated with conventional western medicine,and the observation group was treated with Zhitong Rushen Decoction modified fumigation.The total effective rate,clinical symptoms and the total incidence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P＜0.05).After treatment,the anal edema score,bleeding score and anal distension score of the observation group were lower than those of the control group,the differences were statistically significant(P＜0.05).The total incidence of adverse reactions of the observation group was lower than that of the control group,the difference was statistically significant(P＜0.05).Conclusion The effect of Zhitong Rushen Decoction modified fumigation in the treatment of hemorrhoids is significant,which can not only greatly improve the clinical treatment effect,but also improve the clinical symptoms and clinical manifestations of patients,reduce the incidence of adverse reactions,which is suitable for clinical implementation and promotion. 2021 Vol. 28 (17): 173-175 [Abstract] ( 42 ) HTML (31 KB)  PDF  (0 KB)  ( 6 ) 176 Clinical effect of acupuncture at Dazhui and Baihui of Governor Vessel as main points in treatment of vascular mild cognitive impairment MENG Fan-ying; WAN Ying Objective To investigate the clinical effect of acupuncture at Dazhui and Baihui of Governor Vessel as the main points in the treatment of vascular mild cognitive impairment.Methods Sixty patients with vascular mild cognitive impairment admitted to Mentougou Hospital of Traditional Chinese Medicine from January 2017 to January 2020 were selected as subjects.They were divided into the acupuncture group and the medication group by the random number table method,with 30 patients in each group.The two groups were both treated with secondary prevention of cerebrovascular disease and repeated transcranial magnetic stimulation.The acupuncture group were given acupuncture at Dazhui and Baihui of Governor Vessel as the main points combined with dialectical selection of other points,at the frequency of 3 times per week.The medication group were given oral Donepezil Hydrochloride 5 mg,once a day.After completing the 12-week treatment according to the study requirements,the changes of the scores of Montreal cognitive assessment scale(MoCA),concise mental state scale(MMSE)and picture clock test(CDT)were observed in the two groups,and the therapeutic effect of the two groups was compared.Results After treatment,the scores of MoCA,MMSE,and CDT in the two groups were higher than those before treatment,with statistically significant differences(P＜0.05).After treatment,the scores of MoCA,MMSE,and CDT in the acupuncture group were higher than those in the medication group,with statistically significant differences(P＜0.05).After treatment,the total effective rate of the acupuncture group was 93.33%,and that of the medication group was 60.00%.The total effective rate of the acupuncture group was higher than that of the medication group,with statistically significant difference(P＜0.05).Conclusion Acupuncture at Dazhui and Baihui of Governor Vessel as the main points combined with dialectical selection of other points can effectively improve the cognitive function of patients with vascular mild cognitive impairment,which is worthy of promotion. 2021 Vol. 28 (17): 176-179 [Abstract] ( 40 ) HTML (39 KB)  PDF  (0 KB)  ( 5 ) 180 Effect of Kangfuxin Liquid combined with Jinhoujian in the treatment of oral herpes of hand-feet-mouth disease YAN Shu-yan; DAI Ru-jun Objective To investigate and analyze the effect of Kangfuxin Liquid combined with Jinhoujian in the treatment of oral herpes of hand-feet-mouth disease.Methods A total of 50 children with oral herpes from hand-feetmouth disease admitted to Qingyuan People′s Hospital from April 2019 to April 2020 were selected as the research subjects.They were divided into control group(20 cases)and study group(30 cases)according to the random number table method.The control group was given Jinhoujian treatment,while the research group was given Jinhoujian combined with Kangfuxin Liquid treatment.The curative effect,healing time of oral herpes and normal eating time were compared between the two groups.Results The total effective rate of the study group was higher than that of the control group,the difference was statistically significant(P＜0.05).The average healing time of oral herpes in the study group and the time to return to normal eating were shorter than those in the control group,the difference was statistically significant(P＜0.05).Conclusion The combined treatment of Jinhoujian and Kangfuxin Liquid can significantly improve the effective rate and shorten the healing time of oral herpes in children with hand-foot-mouth disease. 2021 Vol. 28 (17): 180-182 [Abstract] ( 50 ) HTML (30 KB)  PDF  (0 KB)  ( 5 ) 183 Effect of Shoutai Pills combined with low molecular weight Heparin in the treatment of patients with unexplained recurrent spontaneous abortion WAN Zhong-yan; CHEN Chang-qian; KUANG Ai-hua Objective To explore the effect of Shoutai Pills combined with low molecular weight Heparin in the treatment of patients with unexplained recurrent spontaneous abortion.Methods A total of 120 patients with unexplained recurrent spontaneous abortion(URSA)who admitted to Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine from January 2017 to January 2020 were selected as the research objects.According to the random number table method,the patients were divided into the control group and the study group,with 60 cases in each group.The control group was treated with traditional placenta therapy combined with low molecular weight Heparin.The study group was treated with Shoutai Pills.After two months of treatment,the patients in study group would try to get pregnant.After pregnancy,the patients would continue to be treated with Shoutai Pills combined with low molecular weight Heparin.The rates of successful fetal protection and total incidence of adverse reactions in two groups were compared.Results The success rate of fetal protection in the study group(83.3%)was higher than that in the control group(65.0%),and the difference was statistically significant(P＜0.05).There was no significant difference in the total incidence of adverse reactions between the treatment group(20.0%)and the control group(15.0%)(P＞0.05).Conclusion Shoutai Pills combined with low molecular weight Heparin in the treatment of URSA patients can significantly improve the success rate of fetal protection,and the total incidence of adverse reactions is low.This method is safe and effective,and is worthy of clinical application. 2021 Vol. 28 (17): 183-185转189 [Abstract] ( 47 ) HTML (32 KB)  PDF  (0 KB)  ( 6 ) 186 Clinical effect of Banxia Xiexin Decoction combined with Western medicine in treating patients with gastric ulcer due to weakness of spleen and stomach ZHANG Ya-qing Objective To explore the clinical effect of Banxia Xiexin Decoction combined with Western medicine in the treatment of gastric ulcer patients with weak spleen and stomach.Methods From March 2019 to March 2020,120 cases of gastric ulcer patients with spleen and stomach weakness syndrome admitted to the Department of Gastroenterology,Huludao Central Hospital in Liaoning Province were selected as the research objects,and they were divided into the experimental group and the control group according to the random number table method,with 60 cases in each group.The control group was treated with conventional Western medicine,and the experimental group was combined with Banxia Xiexin Decoction on the basis of the control group.Both groups were treated for 1 month.The clinical efficacy,traditional Chinese medicine(TCM)symptom and sign scores,the incidence of adverse reactions and the recurrence after half a year follow-up were compared between the two groups.Results After treatment,the total effective rate of the experimental group was higher than that of the control group,and the difference was statistically significant(P＜0.05).After treatment,the scores of vomiting clear water,stomach noise,lazy speech,shortness of breath,acid reflux,epigastric tiredness after eating,loose stools,epigastric/fleshy distension in the experimental group were lower than those in the control group,and the differences were statistically significant(P＜0.05).The total incidence of adverse reactions in experimental group was lower than that in control group,and the difference was statistically significant(P＜0.05).The recurrence rate in experimental group was lower than that in control group,and the difference was statistically significant(P＜0.05).Conclusion Banxia Xiexin Decoction combined with Western medicine has high clinical value in the treatment of gastric ulcer patients with syndrome of spleen and stomach weakness. 2021 Vol. 28 (17): 186-189 [Abstract] ( 56 ) HTML (32 KB)  PDF  (0 KB)  ( 6 ) 190 Analysis on the incidence and drug resistance of extended spectrum βlactamases in Klebsiella and Escherichia coli from patients with hospital acquired pneumonia GONG Wei; CHEN Ying-hua; ZHAO Jian-min Objective To analyze the incidence and drug resistance of extended spectrum β-lactamases in Klebsiella and Escherichia coli from patients with hospital acquired pneumonia.Methods A total of 104 patients with hospital acquired pneumonia admitted to the First People′s Hospital of Ji′an City from March 2018 to January 2020 were selected for retrospective analysis.The DL-96Ⅱwas mainly used for drug sensitivity test and strain identification,extended spectrum β-lactamases were detected by Kirby-Bauer method,and their incidence and drug resistance characteristics were analyzed.Results There was no significant difference in the positive rate of extended spectrum β-lactamases between Klebsiella and Escherichia coli(P>0.05).Extended spectrum β-lactamases in Escherichia coli showed drug resistance to Ampicillin,Paediatric Compound Sulfamethoxazole Tablets,Aztreonam,Cefperazone/Sulbactam,Piperacillin/Tazobactam,Ceftazidime,Levofloxacin,Imipenem,Cefoxitin and Amikacin,and promoted over time.Conclusion The incidence of extended spectrum β-lactamases in Klebsiella and Escherichia coli from patients with hospital acquired pneumonia is high,and drug resistance also shows gradually increasing trend in recent years. 2021 Vol. 28 (17): 190-192 [Abstract] ( 39 ) HTML (28 KB)  PDF  (0 KB)  ( 6 ) 193 Changes of FeNO and its relationship with serum IgE expression in children with allergic asthma ZHOU Feng;XU Jie;ZHONG Lin Objective To explore the changes of fractional exhaled nitric oxide(FeNO)and its relationship with serum immunoglobulin(IgE)expression in children with allergic asthma.Methods From March 2018 to may 2020,120 children with allergic asthma admitted to Jiangmen Maternal and Child Health Hospital were selected as the observation group,while 120 children without allergic asthma were selected as the control group.The FeNO and serum IgE levels of the two groups were compared,the correlation between FeNO and serum IgE was analyzed,the receiver operating characteristics(ROC)curves of the subjects were drawn,and the efficacy of single or combined FeNO and serum IgE in the diagnosis of allergic asthma was analyzed.Results The FeNO and serum IgE levels in the observation group were higher than those in the control group,the differences were statistically significant(P＜0.05). Pearson correlation showed that FeNO and serum IgE levels were positively correlated(r=0.743, P＜0.05).The AUC of FeNO and serum IgE combined diagnosis of allergic asthma was 0.917,the specificity and sensitivity were 0.932 and 0.727 respectively,the specificity was higher than the single detection of each index.Conclusion The levels of FeNO and IgE in children with allergic asthma are significantly increased,and the two are positively correlated.Combined detection could improve the detection rate of allergic asthma and could be used as a common index for early screening of allergic asthma. 2021 Vol. 28 (17): 193-195 [Abstract] ( 33 ) HTML (32 KB)  PDF  (0 KB)  ( 6 ) 196 Causes of weak agglutination on the secondary side of cross-matching with micro-column gel test and countermeasures of matching ZHU Jie-hao ;YE Huo-mei ;SUN Qin-jie Objective To investigate the causes of weak agglutination on the secondary side of cross matching with micro-column gel test(MGT)and the countermeasures of matching.Methods A total of 3606 blood samples collected from September 2019 to October 2020 in Yunfu People′s Hospital were included in the study.The direct anti-human globulin test(DAT)was performed on the samples with weak agglutination on the secondary side of MGT cross-matching blood,and the antibody screening test was performed on donors.The causes of weak agglutination on the secondary side of MGT cross-matching blood were analyzed,and the corresponding matching countermeasures were discussed.Results There were 120 cases of secondary weak agglutination in the 3606 blood samples,including 117 cases of DAT positive,2 cases of positive donor antibody screening,and 1 case of false agglutination.Further immunophenotyping and diffusion tests were performed on the five DAT-positive specimens with obvious jaundice.The results showed that all five specimens were IgG-type,four were all negative for antibody screening after diffusion,and one was all positive for antibody screening after diffusion.Conclusion 97.50% of the cases of weak agglutination on the secondary side of MGT cross-matching blood are caused by DAT positivity in patients,and the agglutination intensity on the secondary side of cross-matching blood is not stronger than that of DAT in patients.For the specimen with DAT positive and obvious jaundice,in order to improve the safety and effectiveness of blood transfusion,the causes should be found and the corresponding blood matching scheme should be taken. 2021 Vol. 28 (17): 196-198 [Abstract] ( 41 ) HTML (30 KB)  PDF  (0 KB)  ( 7 ) 199 Identification of pathogenic bacteria and analysis of drug sensitivity test results in patients with sepsis in a hospital from 2017 to 2019 ZHANG Man-jia Objective To analyze the pathogen identification and drug sensitivity test results of sepsis patients in Huludao Central Hospital from 2017 to 2019.Methods A total of 896 patients with sepsis admitted to Huludao Central Hospital from January 2017 to December 2019 were selected,and 386 strains of pathogenic bacteria isolated from their venous blood culture were identified and drug sensitivity test detected.Results Among the 386 strains of pathogenic bacteria, Alkalobacter, Serrata marcescens, Burkholderia, Pseudomonas, Stenotrophomonas maltophilia and coagulasenegative Staphylococcus were the six species with the highest proportion.The 149 Gram-positive cocci showed higher resistance rates to Erythromycin,Clindamycin,Penicillin and Oxacillin,and were sensitive to Tegacycline,Linezolid,Vancomycin and Rifamequin.The 230 Gram-negative bacilli showed high drug resistance to Polymyxin B and Amtronam,and were sensitive to Imipenem,Cefoperazone,Minoccyccline,Cotrimoxazole,Cefepime,Ceftazidime, etc.Conclusion By identifying strains from the venous blood culture isolates of sepsis patients,the main pathogenic bacteria were Alkalogenic bacilli, Serrata marcescens, Burkholderia, Pseudomonas, Stenotrophomonas maltophilia,coagulase -negative Staphylococcus.There were many species of strains,and drug resistance of different strains was also different.Generally,the strains were sensitive to Cotrimoxazole,Imipenem,Cefepime,Ceftazidime,Tigacycline,Vancomycin and Rifamequin. 2021 Vol. 28 (17): 199-202 [Abstract] ( 36 ) HTML (30 KB)  PDF  (0 KB)  ( 6 ) 203 Prevalence of hypertension among employees of an aircraft manufacturing enterprise and the effect of occupational noise exposure on blood pressure JIANG Feng;WAN Ni-na;GUO Xu;LIAO Jun-ting; LIU Ying-ji;YUAN Xiao-hong;YANG Ying; XING Li-ying▲ Objective To study the effect of occupational noise exposure on employees′ blood pressure by analyzing the health examination data of employees in an aircraft manufacturing enterprise,and provide a theoretical basis for the prevention and control of cardiovascular diseases in noise-exposed employees.Methods A cross-sectional survey method was used to collect information on the health and noise exposure of 2097 employees from an aircraft manufacturing enterprise from March to August 2015,and the impact of noise exposure on employees′ blood pressure was analyzed.Results The prevalence of hypertension among employees was 36.8%(772/2097).The prevalence of hypertension among employees in the noise-exposed group was higher than that in the non-noise-exposed group,the difference was statistically significant(39.9% vs. 32.9%,χ2=10.935, P=0.001).The systolic blood pressure of the noiseexposed group and the non-noise-exposed group were(134.34±18.14)and(130.37±18.48)mmHg,respectively,and the diastolic blood pressure was(82.87±13.33)and(81.17±12.81)mmHg,respectively.The systolic and diastolic blood pressures of the employees in the noise-exposed group were higher than those in the non-noise-exposed group,and the differences were statistically significant(P＜0.05).Conclusion Noise-exposed employees have a high prevalence of hypertension.The targeted primary prevention on this population should be emphasized. 2021 Vol. 28 (17): 203-205转210 [Abstract] ( 46 ) HTML (33 KB)  PDF  (0 KB)  ( 6 ) 206 Monitoring of iodine nutritional status in middle-aged and elderly population and investigation research on the influencing factors of Hashimoto′s thyroiditis WU Xia-wen ;DUAN Zong-mei ;ZHUANG Xiu-yun; HAN Ting-ping ;YE Guang-li Objective To clarify the iodine nutritional status of middle-aged and elderly people,to guide the residents to supplement iodine scientifically,and to explore the risk factors of Hashimoto′s thyroiditis,so as to provide scientific basis for the prevention and treatment of thyroid diseases.Methods Stratified sampling was used to select 600 middleaged and elderly people who were hospitalized and underwent health check-ups in Changqing People′s Hospital of Ji′nan City from May 2019 to January 2020.The survey subjects were from the permanent residents of various towns and streets in Changqing District,the clinical data of gender,age,medical history,blood pressure,blood lipids,thyroid function and thyroid ultrasound examination were collected,and urine iodine test was performed.A total of 56 patients who met the diagnostic criteria for Hashimoto′s thyroiditis were regarded as the Hashimoto group,and 401 subjects with no significant difference in age structure from the Hashimoto group were selected as the control group.Single factor analysis and multivariate Logistic regression were used to analyze the possible influencing factors for incidence of Hashimoto′s thyroiditis.Results The median urinary iodine was 152.7 μg/L,61 cases(10.17%)were iodine deficient,and 39 cases(6.50%)were iodine excess.There were statistically significant differences in the incidence of hypertension and the proportion of no comorbidities between the two groups(P＜0.05).There were no significant differences in gender,age,smoking history,drinking history,dyslipidemia,cerebral infarction,coronary heart disease,diabetes between the two groups(P＞0.05).There were statistically significant differences in the serum thyroid stimulating hormone(TSH),thyroglobulin antibody(TGAb)and thyroid peroxidase antibody(TPOAb)levels between the two groups(P＜0.05).There were no significant differences in the levels of free triiodothyronine(FT3),free thyroxine(FT4)and urine iodine between the two groups(P＞0.05).The results of multivariate Logistic regression analysis showed that TSH(OR=1.251,95%CI: 1.163-1.346, P＜0.05),TGAb(OR=1.016,95%CI: 1.012-1.020, P＜0.05),TPOAb(OR=1.010,95%CI:1.006-1.014, P＜0.05)were risk factors for incidence of Hashimoto′s thyroid,no comorbidities were protection factors for incidence of Hashimoto′s thyroid(OR=0.188,95%CI: 0.054-0.653, P＜0.05).Conclusion Population surveyed are generally at the appropriate level of iodine nutrition,with large individual differences.Some iodine deficient people are caused by blindly avoiding iodine diet.No comorbidities are the protective factor of Hashimoto′s thyroiditis,and TSH,TGAb and TPOAb are the risk factors of Hashimoto′s thyroiditis.The risk of Hashimoto′s thyroiditis increases by 1.251 times when TSH increases by 1 unit. 2021 Vol. 28 (17): 206-210 [Abstract] ( 29 ) HTML (43 KB)  PDF  (0 KB)  ( 7 ) 211 Relationship between job burnout and state of mind among nurses in emergency department NIAN Jing Objective To explore the relationship between job burnout and state of mind of nurses in emergency department.Methods From January 2019 to May 2020,50 emergency department nurses without job burnout in Fushun Central Hospital were selected as the control group,and 50 nurses with job burnout in Fushun Central Hospital during the same period were selected as the observation group.Mood state scale(POMS)and Zung scale were used to evaluate the mood state of the two groups.The POMS scale and Zung scale scores of the two groups were compared,and the above scale scores of nursing staff with different degrees of job burnout in the observation group were compared,and the relationship between the POMS scale and Zung scale scores and job burnout degree was analyzed.Results The POMS scores of energy and self-esteem in the observation group were lower than those in the control group,and the scores of tension,anger,fatigue,depression and panic in the observation group were higher than those in the control group,the differences were statistically significant(P＜0.05).Zung scale scores in the observation group were higher than those in the control group,and the differences were statistically significant(P＜0.05).In the observation group,the POMS scores of energy and self-esteem of nurses with severe job burnout were lower than those of mild and moderate patients,other scores were higher than those of mild and moderate patients,and Zung scores were higher than those of mild and moderate patients,and the differences were statistically significant(P＜0.05).Correlation analysis showed that the energy and self-esteem scores of POMS scale were negatively correlated with job burnout,while the scores of other POMS scales and Zung scale were positively correlated with job burnout(P＜0.05).Conclusion The job burnout of nurses in emergency department is closely related to their state of mind,it is necessary to pay attention to the psychological counseling and humanistic care of nurses in emergency department. 2021 Vol. 28 (17): 211-214 [Abstract] ( 34 ) HTML (35 KB)  PDF  (0 KB)  ( 6 ) 215 Influence of video surveillance on the quality of nursing management in psychiatric department ZHENG Gui-qin ;PENG He-ping ;ZHOU Xin-ying ;ZHOU Wen-qin Objective To explore the influence of video surveillance on the quality of nursing management in psychiatric department.Methods From June 2016 to May 2017,60 nurses from 4 wards with video surveillance installed in the Psychiatric Department of Ji′an Third People′s Hospital were selected as the observation group,and 60 nurses from 4 wards with no video surveillance installed from June 2015 to May 2016 were selected as the control group.The irregularities of the two groups at work were compared.The self-made psychiatric nursing work and psychological stress questionnaire,nursing job satisfaction questionnaire were used to assess the psychological status of nurses,adopting stress management coping strategies and job satisfaction in the two groups,and the occurrence of adverse events of patients during this period was recorded.Results The proportion of irregularities of nurses at work in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).The total incidence of adverse events in the observation group was 5.93%,which was lower than 24.06% in the control group,and the difference was statistically significant(P＜0.05).After adopting stress management and various coping strategies,the nurses′ work and psychological stress in the observation group were lower than those in the control group,the nursing job satisfaction was higher than that in the control group,and the differences were statistically significant(P＜0.05).Conclusion The application of video surveillance can standardize nurses′ behavior,reduce the incidence of adverse events,improve the level of nursing management,and improve the quality of nursing safety management.Adopting active stress management and coping strategies can relieve nurses′ work and psychological stress,and improve nurses′satisfaction with their work. 2021 Vol. 28 (17): 215-217转222 [Abstract] ( 37 ) HTML (34 KB)  PDF  (0 KB)  ( 10 ) 218 Quantitative analysis of domestic and foreign literatures on spleen qi deficiency in rats HU Jing-wen; WENG Mei-hua ;ZHOU Hong-juan ;CHEN Jin-xiu▲ Objective To understand the research status and development trend of this field,in order to provide reference for the related research of spleen qi deficiency rats.Methods China National Knowledge Infrastructure(CNKI),Wanfang Database,VIP Database and Web of Science Database(WOS)were used as data sources to retrieve relevant literatures on the studies of spleen qi deficiency rats from the establishment of the database to December 2019.The statistics were carried out from two aspects,publication year and high frequency keywords.CiteSpace 5.5.R2 software was used to draw the visual atlas of co-occurrence network of keywords in the study of spleen qi deficiency rats,and the research status in this field was preliminally analyzed.Results A total of 355 literatures in Chinese and 16 literatures in English were retrieved,and the total number of published articles of literatures in Chinese showed an increasing trend year by year,reaching the peak in 2017-2018.Key words analysis of literature showed that research directions focused on related interventions,related syndrome types and target studies in rats with spleen qi deficiency,among which energy metabolism in animal models was the focus of current research.Conclusion The rats with spleen qi deficiency have high experimental value,and the research shows a trend of diversified development,and the research quality is also improving constantly.From the perspective of molecular biology,the study of various intervention methods for the intervention targets of the rats with spleen qi deficiency,especially the study of energy metabolism,is the main direction of future research.This study provides some reference for the topic selection and development direction of the study on the rats with spleen qi deficiency. 2021 Vol. 28 (17): 218-222 [Abstract] ( 37 ) HTML (39 KB)  PDF  (0 KB)  ( 8 ) 223 Survey of Technical Operation Specification for Intravenous Treatment and Nursing training for nurses in 14 primary hospitals CHEN Jun-Xin ;HUANG Xi-mei;SHI Guang ;MO Qi-shan Objective By investigating the training and mastery of the Technical Operation Specification for Intravenous Treatment and Nursing(WS/T433-2013)(hereinafter referred to as the Standard for Intravenous Treatment)in different levels of primary hospitals in Panyu District,the paper provides a basis for the training needs and application of the Standard for Intravenous Treatment in primary medical institutions.Methods A self-designed questionnaire was used to investigate the training status of Standard for Intravenous Treatment,and 2588 nursing staff from 14 primary medical institutions in Panyu District were investigated by convenience sampling method.Results The assessment scores of nurses with more training times were higher than those with less training times,and the differences among nurses with different training forms were statistically significant(P＜0.01).The nurses who thought the Standard for Intravenous Treatment was very helpful to practical work had higher scores,and the nurses with higher proficiency in the Standard for Intravenous Treatment had higher scores,and the differences were statistically significant(P＜0.01).There was statistical significance in the evaluation scores of nursing staff in different levels of hospitals(P＜0.01).The scores of nurses with bachelor degree or above were higher than those with junior college degree or below,and the scores of head nurse or above were higher than those of responsible nurses,and the differences were statistically significant(P＜0.05).Conclusion The level of training is affected by the hospital level,education background,position,training form,training frequency and the understanding of Standard for Intravenous Treatment in practical work.The primary hospitals need to further enrich training forms and channels to ensure the quality of training. 2021 Vol. 28 (17): 223-226 [Abstract] ( 37 ) HTML (36 KB)  PDF  (0 KB)  ( 6 ) 227 Application study of maker education mode in first-time insulin injection education in outpatients PENG Fang-yi ;CHEN Si-ping ;XU Yan-feng Objective To study the application effect of maker education mode in first-time insulin injection education in outpatients.Methods A total of 60 patients with diabetes who were admitted to Pingxiang People′s Hospital from October 2019 to July 2020 were seleccted as the research objects and divided into the control group and the observation group according to random number table method,with 30 cases in each group.The control group was given routine education mode intervention,and the observation group was given maker education mode intervention.The mastery of insulin knowledge and injection technique,qualified rate of blood glucose,level of glycated hemoglobin and satisfaction of patients were compared between two groups.Results The total mastery rate of insulin knowledge and injection technique,total satisfaction rate and the qualified rate of blood glucose in the observation group were higher than those in the control group,the level of glycated hemoglobin in the observation group was lower than that in the control group,and the differences were statistically significant(P＜0.05).After 3 weeks of the intervention,the scores of physiological function,physiological function,physical pain,energy,social function,emotional function,mental health and general health status of the two groups were higher than those before intervention,and the observation group was higher than the control group,and the differences were statistically significant(P＜0.05).Conclusion Maker education mode can increase the level of insulin injection and satisfaction,decrease the level of blood glucose,and promote better prognostic development. 2021 Vol. 28 (17): 227-229转233 [Abstract] ( 47 ) HTML (33 KB)  PDF  (0 KB)  ( 4 ) 230 Application effect of mind map health education in family members of children with allergic purpura LI Xiao-ping;CHEN Xiao-li;LIU Ji Objective To explore the application effect of mind map health education in the family members of children with allergic purpura.Methods Forty-six children with allergic purpura who were admitted to the Second Affiliated Hospital of Yichun University and their family members from October 2017 to June 2020 were selected as the research subjects.They were divided into two groups according to the random number table method,with 23 cases in each group.Participants in the control group used traditional health education,and in the observation group,mind map health education was adopted.The disease awareness of children′s family members,care behavior compliance,and disease recurrence were compared in the two groups.Results The children′s family members of the observation group had higher disease awareness after intervention than that of the control group,and the children′s family members′awareness of the disease after the intervention in the two groups was higher than that before the intervention with statistical significance(P＜0.05).The care compliance rate was 95.65% in the observation group,higher than 65.22% in the control group,and the difference was statistically significant(P＜0.05).The disease recurrence rate of children in the observation group was 4.35%,lower than 34.78% in the control group,and the difference was statistically significant(P＜0.05).Conclusion Mind map health education can improve the disease awareness and care compliance of the family members of children with allergic purpura,and is beneficial for recurrence rate reduction and prognosis improvement. 2021 Vol. 28 (17): 230-233 [Abstract] ( 58 ) HTML (34 KB)  PDF  (0 KB)  ( 6 ) 234 Clinical application effect of using incontinence-associated dermatitis with Aloe Vera and South African leaf dressing MAI Li-xin; WANG Min-zhu ;WU Li-rong Objective To explore the clinical effect of external application of aloe and South African leaf compound fresh dressing on incontinence-associated dermatitis(IAD).Methods A total of 100 patients with IAD admitted to Shunde Hospital of the Guangzhou University of Traditional Chinese Medicine from January 2018 to June 2019 were selected as the research objects.They were divided into two groups according to the random number table method,50 cases in each group.The control group used of Zinc Oxide Ointment on the basis of routine skin care,while the observation group used of Compound Fresh dressing on the basis of routine skin care(mixed proportion of aloe and South African leaf juice was 4∶1).The total effective rate,cure time and nursing satisfaction of the two groups were observed and recorded after 5 days of treatment.Results The total effective rate of the observation group was 100%,higher than that of the control group 88%,and the nursing total satisfaction of the observation group was 96%,higher than that of the control group 60%,the differences were statistically significant(P＜0.05).The skin wound healing time of the observation group was(3.61±2.52)d,shorter than that of the control group of(6.83±3.42)d,the difference was statistically significant(P＜0.05).Conclusion Aloe and South African Leaf compound fresh dressing can improves the therapeutic effect and nursing satisfaction for the treatment of IAD,shortens the cure time,and is a practical and effective new method for the treatment of IAD,which is worthy of wide promotion in the clinical and domestic settings. 2021 Vol. 28 (17): 234-236 [Abstract] ( 50 ) HTML (30 KB)  PDF  (0 KB)  ( 6 ) 237 Application research of ″distributed″ telemedicine in male infertility LIU Yan; WANG Rong-qin; HU Wen-qian ;HUANG Jing-ya ;DING Yan-ping Objective To explore the application value of ″distributed″ telemedicine in male infertility.Methods A retrospective analysis 100 male infertility and asthenospermia patients who were treated in Nanchang Reproductive Hospital from January 2018 to January 2020 as the research objects,they were divided into the control group and the observation group according to different intervention methods,50 cases in each group.The control group implemented faceto-face medical treatment.the observation group implemented the ″distributed″ telemedicine model,the satisfaction,expenditure and time of the two groups were compared.Results There was no statistically significant difference in the total effective rate between the two groups after treatment(P＞0.05).The mediccal visits time of the observation group was shorter than that of the control group and medical expenses was lower than that of the control group,the differences were statistically significant(P＜0.05).The total satisfaction of the observation group was higher than that of the control group,and the difference was statistically significant(P ＜0.05).Conclusion The implementation of ″distributed″telemedicine in male infertility visits can shorten the time of patients′ visits,reduce medical expenses and increase the satisfaction rate,which is worthy of application. 2021 Vol. 28 (17): 237-239 [Abstract] ( 47 ) HTML (32 KB)  PDF  (0 KB)  ( 8 ) 240 Application effect of whole-course nursing intervention in patients with acute cardiac tamponade during cardiac intervention WANG Ren-hong ;ZHONG Wen ;TAN Gu-yu ;ZHOU Liang ;LI Yi▲ Objective To explore the application effect of whole-course nursing intervention in patients with acute pericardial tamponade during cardiac intervention.Methods A total of 56 patients with acute pericardial tamponade during cardiac intervention in the Second Affiliated Hospital of Nanchang University from January 2017 to December 2019 were selected as the research subjects.They were divided into the reference group and the nursing group by lottery,28 cases in each group.Patients in the reference group received conventional nursing.In the nursing group,whole-course nursing intervention was used.The amount of intraoperative blood loss,the time of operation,hospital stay,hospitalization cost,and nursing effectiveness rate were compared between the two groups.Results The amount of intraoperative blood loss of the nursing group was less than that in the reference group,the hospitalization cost in the nursing group was lower than that in the reference group,and the time of operation and the hospital stay of the nursing group were shorter than those in the reference group,the differences were statistically significant(P＜0.05).The total nursing effectiveness rate of the nursing group was 96.43%,higher than that of the reference group accounting for 75.00%,and the difference was statistically significant(P＜0.05).Conclusion The whole-course nursing intervention during cardiac intervention with acute cardiac tamponade can reduce the amount of intraoperative blood loss.The operation can be performed smoothly,and the patients can recover fast after operation,which has clinical significance and can be preferred. 2021 Vol. 28 (17): 240-242 [Abstract] ( 28 ) HTML (30 KB)  PDF  (0 KB)  ( 5 ) 243 Application of family rehabilitation simulation ward in home nursing system of stroke patients GUO Yu;HONG Zhen-lan; WANG Miao-miao;MA Shu-li;LI Xue-lian;GAO Cong-shan Objective To explore the influence of family-style rehabilitation simulation wards in home rehabilitation nursing for patients after stroke.Methods A total of 60 stroke patients who were in the recovery period in Shanxi Provincial Acupuncture Hospital from December 2018 to December 2019 were selected.They were divided into the control group and the observation group by random number table method,30 cases in each group.The control group was given routine care and follow-up after discharge.On the basis of the control group,the observation group lived in a family-style rehabilitation simulation ward 1-2 weeks before discharge,and developed a personalized home rehabilitation training program for stroke patients.Before the intervention and 4 weeks after discharge,after 12 weeks,the patient′s self-efficacy energy scale and Barthel index rating scale score were compared.Results Before the intervention,there were no difference in the scores of the two groups of patients on the self-efficacy scale and the Barthel index rating scale.4 weeks after discharge and 12 weeks after the observation group,the self-efficacy scale and the Barthel index rating scale scored at each time period were higher than those of the control group,the differences were statistically significant(P＜0.05).Conclusion Family rehabilitation simulation ward can effectively improve the self-rehabilitation efficiency and activities of daily living of stroke patients in home care,ensure the continuity of rehabilitation treatment,and improve the quality of life of patients. 2021 Vol. 28 (17): 243-246 [Abstract] ( 51 ) HTML (41 KB)  PDF  (0 KB)  ( 8 ) 247 Application value of the whole-course responsibility nursing model in the nursing of parturient with postpartum hemorrhage caused by uterine inertia and cesarean section XU Qiao-ying Objective To analyze the application value of the whole-course responsibility nursing model in the nursing of parturient with postpartum hemorrhage caused by uterine inertia and cesarean section.Methods The clinical data of 60 parturient with postpartum hemorrhage caused by uterine inertia and cesarean section treated in Ruijin Maternal and Child Health Hospital from January 2018 to May 2019 was retrospectively analyzed,they were divided into the control group(n=33)and the observation group(n=27)by the nursing methods difference.The control group was used routine nursing,the observation group was used whole course responsibility nursing mode.The amount of postpartum hemorrhage,anxiety and depression were compared between the two groups.Results The total amount of bleeding 24 hours after delivery was higher than that 2 hours after delivery,the total amount of bleeding within 2 hours and 24 hours after delivery in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).Before intervention,the scores of the self-rating anxiety scale(SAS)and self-rating depression scale(SDS)of the two groups,there were no statistical significant differences(P＞0.05);after 5 days of intervention,the SAS and SDS scores of the two groups were lower than those before intervention,and the SAS and SDS scores of the observation group were lower than those of the control group,the differences were statistically significant(P ＜0.05).Conclusion The full-course responsibility nursing model has a good application effect in the nursing of parturient with postpartum hemorrhage caused by uterine inertia and cesarean section.It can effectively control the amount of postpartum hemorrhage of the parturient,improve the anxiety and depression of the parturient,and has a positive significance for postpartum recovery. 2021 Vol. 28 (17): 247-249 [Abstract] ( 42 ) HTML (31 KB)  PDF  (0 KB)  ( 5 ) 250 Application of integrated nursing mode of CT room ward in preoperative preparation of patients with CT coronary angiography HU Xi-e; LI Qian-fang ;MA Hua Objective To explore the application effect of CT room ward integrated nursing mode in the preparation of patients with CT coronary angiography before examination(CTA).Methods A total of 72 cases CTA checkers admitted to Shenzhen Yantian District People′s Hospital from January 2018 to December 2019 were selected and divided into the control group(36 cases)and the observation group(36 cases)according to the method of drawing lots.The control group adopted the conventional nursing mode,and the observation group adopted the integrated nursing mode of CT room ward.The image quality of the two groups was compared,and the examination indexes(waiting time,examination time,radiation exposure,respiratory training time after nursing,heart rate control time）,nursing satisfaction were compared.Results The total qualified rate of image quality in the observation group was higher than that in the control group,the difference was statistically significant(P＜0.05).The waiting time,examination time,breathing training time,heart rate control time in the observation group were shorter than those in the control group,the radiation dose was lower than that in the control group,the differences were statistically significant(P＜0.05).The nursing total satisfaction in the observation group was higher than that in the control group,the difference was statistically significant(P＜0.05).Conclusion CT room ward integrated nursing mode was adopted for patients undergoing CTA.It can improve the image quality of patients,shorten the relevant time of examination index,reduce the radiation dose,and have high patient satisfaction and significant value. 2021 Vol. 28 (17): 250-252 [Abstract] ( 47 ) HTML (31 KB)  PDF  (0 KB)  ( 6 ) 253 Effect of intensive nursing mode on accuracy of inhalation dosage and pulmonary function in elderly patients with chronic obstructive pulmonary disease ZHAO Qin-qin Objective To investigate the effects of intensive nursing mode on the accuracy of inhalation dosage and lung function in elderly patients with chronic obstructive pulmonary disease(COPD).Methods A total of 200 elderly patients with COPD admitted to the First People's Hospital of Fuzhou in May 2019 and April 2020 were selected as the research objects and divided into observation group(100 cases)and control group(100 cases)according to the random number table method.The observation group was treated with centralized nursing method,while the control group was treated with routine nursing method.The improvement of lung function indexes and the correct rate of inhalation preparation were compared between the two groups.Results After nursing,the forced vital capacity(FVC),forced expiratory volume in the first second(FEV1)and FEV1/FVC of observation group were lower than those of before nursing,and the FVC,FEV1 and FEV1/FVC of the observation group were lower than those of the control group after nursing,the differences were statistically significant(P＜0.05).The scores of inhalant use and the correct rate of inhalant use in observation group were higher than those in control group after nursing,and the differences were statistically significant(P＜0.05).Conclusion Through the implementation of centralized nursing for elderly COPD patients,the accuracy of inhalation dosage and lung function have been greatly improved,and the recovery of patients has been promoted,which is worthy of clinical promotion of this model. 2021 Vol. 28 (17): 253-255 [Abstract] ( 34 ) HTML (31 KB)  PDF  (0 KB)  ( 6 ) 256 Application of Munro pressure ulcer risk assessment scale in prevention of pressure ulcer in patients undergoing laparoscopic radical hysterectomy XIAO Ying ;HUANG Wei ;FENG Miao-qian Objective To explore the application effect of Munro pressure ulcer risk assessment scale(Munro scale)in the prevention of pressure ulcer in patients undergoing laparoscopic radical hysterectomy.Methods A total of 60 patients admitted to Bo′ai Hospital of Zhongshan from May 2018 to April 2019 who underwent laparoscopic extensive total hysterectomy during the period of conventional pressure ulcer assessment were selected as the control group.A total of 60 patients admitted to Bo′ai Hospital of Zhongshan from May 2019 to April 2020 who underwent laparoscopic extensive total hysterectomy during the period of Munro scale were selected as the observation group.The incidence of pressure ulcers in the two groups was compared,and the satisfaction of patients with pressure ulcers in the operating room was investigated.Results The total incidence of pressure ulcer in the observation group was lower than that in the control group,the difference was statistically significant(P＜0.05).The satisfaction of the observation group was higher than that of the control group,the difference was statistically significant(P＜0.05).Conclusion The application of Munro scale in the prevention of pressure ulcers in patients undergoing extensive laparoscopic total hysterectomy has a good effect.The application of Munro scale for preoperative,intraoperative and postoperative evaluation of patients undergoing surgery can reduce the occurrence of pressure ulcers,effectively guarantee patient safety,and thus improve patient satisfaction. 2021 Vol. 28 (17): 256-258转262 [Abstract] ( 42 ) HTML (31 KB)  PDF  (0 KB)  ( 7 ) 259 Effect analysis of iodophor intrauterine swab in prevention of incision infection after emergency cesarean section in high risk pregnant women ZHANG Fen; HUANG Xiao-rong;CHEN Li;YUAN Ting; HU Yi-fang Objective To investigate the effect of iodophor intrauterine swab in preventing incision infection after emergency cesarean section in high-risk pregnant women.Methods The clinical data of 70 cases of high-risk pregnant women undergoing emergency cesarean section in Fuzhou First People′s Hospital,Jiangxi Province from January 2019 to July 2020 were retrospectively analyzed,and they were divided into the reference group(35 cases)and the study group(35 cases)according to different nursing methods.The reference group received routine nursing care,and the study group implemented personalized nursing intervention and iodophor uterine cavity wiping on the basis of routine nursing.The self-rating anxiety scale(SAS),self-rating depression scale(SDS),systolic blood pressure,diastolic blood pressure,heart rate,white blood cell count and postoperative pain score of the two groups before and after intervention were compared.Results There were no significant differences in SAS,SDS,postoperative pain scores,systolic blood pressure,diastolic blood pressure,heart rate and white blood cell count between the two groups before nursing(P＞0.05).The SAS,SDS and postoperative pain scores of the two groups were lower than those before nursing,and the levels of systolic blood pressure,diastolic blood pressure and heart rate were lower than those before nursing,while the white blood cell count was higher than that before nursing,the differences were statistically significant(P＜0.05).The SAS,SDS and postoperative pain scores of the study group were lower than those of the reference group,the systolic blood pressure and diastolic blood pressure were lower than those of the reference group,and the white blood cell count was higher than that of the reference group,the differences were statistically significant(P＜0.05).The incidence of incision infection and uterine cavity retrograde infection in the study group were 8.57% and 2.86%,respectively,which were lower than 28.57% and 17.14% of the reference group,the differences were statistically significant(P＜0.05).The total nursing satisfaction of the study group was 97.14%,higher than 82.86% of the reference group,the difference was statistically significant(P＜0.05).Conclusion The application of iodophor intrauterine swab in the nursing intervention of emergency cesarean section in high-risk pregnant women has exact effect.It can effectively reduce the incidence of postoperative incision infection and uterine cavity retrograde infection,improve the negative emotions of patients,reduce their blood pressure,heart rate and pain,lay a good foundation for maternal body recovery,with higher nursing satisfaction,which is worthy of promotion and application. 2021 Vol. 28 (17): 259-262 [Abstract] ( 40 ) HTML (33 KB)  PDF  (0 KB)  ( 6 ) 263 Application effect of psychological nursing intervention based on the concept of evidence-based medicine in patients with limb fractures JIN Shao-li ;SONG Xue ;LI Xiao Objective To explore the application value of psychological nursing intervention based on the concept of evidence-based medicine in patients with limb fractures.Methods From October 2019 to October 2020,90 patients with limb fractures who underwent surgeries in the Second People′s Hospital of Pingxiang City,Jiangxi Province were selected as the research subjects.They were divided into two groups by the random number table method,45 cases in each group.The patients in the control group adopted conventional nursing,and the patients in the experimental group adopted psychological nursing based on the concept of evidence-based medicine.The two groups mental state,activities of daily living,mastery of disease-related knowledge and postoperative complications were compared.Results Before the intervention,there were no statistical significances in the self-rating anxiety scale(SAS）,the self-rating depression scale(SDS)score,or the asessment of activities of daily living Barthel index(BI)in the two groups(P＞0.05).After the intervention,the SAS and SDS scores of the two groups were lower than before the intervention,and the BI score was higher than that before the intervention,the scores of SAS was(39.31±3.22)and SDS was(41.05±4.13)points of the experimental group,lower than those of the control group of(46.11±4.27)and(47.23±5.11)points,the BI was(79.67±6.21)points in the experimental group,higher than that of the control group of(67.84±5.92）points,the differences were statistically significant(P＜0.05).The disease-related knowledge)mastery of the experimental group after intervention was higher than that in the control group,the incidence of postoperative complications was lower than that in the control group,the differences were statistically significant(P＜0.05).Conclusion Psychological nursing intervention based on the concept of evidence-based medicine can improve the mental state of patients with limb fractures,reduce complications,and improve the mastery of disease knowledge and the ability of daily living activities. 2021 Vol. 28 (17): 263-265转269 [Abstract] ( 45 ) HTML (33 KB)  PDF  (0 KB)  ( 7 ) 266 Nursing effect of risk management measures based on cluster intervention in patients with acute respiratory distress syndrome GAN Na ;PAN Li ;LIU Juan-juan▲ Objective To evaluate the nursing effect of risk management measures based on cluster intervention in patients with acute respiratory distress syndrome(ARDS).Methods Retrospectively extract the clinical data of 85 ARDS patients admitted to Jingzhou Third People′s Hospital in Hubei Province from January 2019 to May 2020 were selected and divide into the control group(42 cases)and the observation group(43 cases)according to different nursing methods,and control group was given routine care,and the observation group was given risk management measures based on cluster intervention.The results of blood gas analysis,the incidence of complications,risk events,and complaint events were compared between the two groups.Results After the intervention,the observation group′s blood oxygen saturation(SaO2)and blood oxygen partial pressure(PaO2)levels were higher than those of the control group,the carbon dioxide partial pressure(PaCO2)was lower than that in the control group,and the differences were statistically significant(P＜0.05).The total incidence of pressure ulcers,unplanned extubation，and hypotension was lower than that of the control group,and the difference was statistically significant(P＜0.05);the incidence of risk events and complaints in the observation group was lower than that of the control group,and the difference was statistically significant(P＜0.05).Conclusion The risk management measures based on cluster intervention have significant nursing effects in ARDS patients,which can effectively improve blood gas analysis,reduce the incidence of patient complications,risk events of nursing staff,and the probability of complaints from patients or their families. 2021 Vol. 28 (17): 266-269 [Abstract] ( 40 ) HTML (34 KB)  PDF  (0 KB)  ( 7 ) 270 Application value of humanized nursing in the treatment of chronic obstructive pulmonary disease patients with non-invasive ventilator LIAO Yuan-yuan ;LIU Shuang-qun Objective To analyze the application value of humanized nursing in the treatment of chronic obstructive pulmonary disease(COPD)patients with non-invasive ventilator.Methods A total of 90 COPD patients treated with noninvasive ventilator therapy in Jingzhou Chest Hospital from February 2018 to December 2019 were selected as the research objects,and these patients were divided into the control group and the observation group according to the random number table method,45 cases in each group.Two groups were treated with noninvasive ventilator after admission,the control group was treated by routine nursing intervention,and the observation group was treated by humanization nursing intervention on the basis of the control group.The changes of blood gas indexes such as partial arterial oxygen pressure(PaO2),partial arterial carbon dioxide pressure(PaCO2),partial arterial oxygen saturation(SaO2)were monitored and recorded before and after nursing intervention of patients in the two groups,and the incidence of complications,endotracheal intubation rate and nursing satisfaction between the two groups were compared.Results The blood gas indexes such as PaO2 and SaO2 in the two groups after nursing were higher than those of before nursing,while PaCO2 was lower than that of before nursing,moreover,the levels of PaO2 and SaO2 in the observation group after nursing were higher than those of the control group,while the level of PaCO2 after nursing in the observation group was lower than that of the control group,the differences were statistically significant(P＜0.05).The total incidence of spontaneous pneumothorax,respiratory failure,right cardiac insufficiency,pulmonary hypertension and the intubation rate in the observation group were lower than those in the control group,the differences were statistically significant(P＜0.05).The total nursing satisfaction of the observation group was higher than that of the control group,the difference was statistically significant(P＜0.05).Conclusion Humanized nursing can significantly improve the blood gas indexes of COPD patients,reduce the incidence of complications and endotracheal intubation rate,improve the nursing satisfaction of patients. 2021 Vol. 28 (17): 270-272转276 [Abstract] ( 44 ) HTML (33 KB)  PDF  (0 KB)  ( 6 ) 273 Influence of prostate cancer patients by continuous nursing based on peer support XIA Jun-na ;ZHU Li-xia; HUA Jian-hong Objective To approach the influence of prostate cancer patients by continuous nursing based on peer support.Methods The 120 cases clinical data of prostate cancer operation patients in Wuxi People′s Hospital in Jiangsu Province from January to August 2020 were analyzed,they were divided into the control group and the peer support group by different nursing intervention,60 cases in each group.The control group was given routine continuity of nursing and continuous nursing based on peer support group was given continuous nursing based on peer support,the selfcare,life quality,self-efficacy,serum prostate specific antigen(PSA),urinary flow rate of two group patients before nursing and after nursing were compared.Results The self-care,life quality score,self-efficacy,PSA,urinary flow rate of two group before nursing were compared,the difference were no statistical significance(P＞0.05);after nursing,selfcare,life quality score,self-efficacy,urinary flow rate of two groups were higher than those before nursing in the same group,PSA was lower than that before nursing in the same group,self-care,life quality score,self-efficacy,urinary flow rate of continuous nursing based on peer support group were higher than those of the control group,PSA was lower than that of the control group,the differences were statistical significance(P＜0.05).Conclusion The application of prostate cancer patients by continuous nursing based on peer support,which could increase self-care,self-efficacy and life quality,decrease PSA,improve urinary flow rate,it is worth to be used. 2021 Vol. 28 (17): 273-276 [Abstract] ( 45 ) HTML (32 KB)  PDF  (0 KB)  ( 7 )

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