铁调素在慢性肾脏病发生及发展中的研究进展

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Abstract Chronic kidney disease(CKD)patients often have multiple complications,and the incidence of renal anemia(RA)gradually increases with the course of CKD.RA not only prolongs the hospital stay of CKD patients,but also affects the survival rate of patients.Therefore,treatment of anemia for CKD patients is particularly critical.There are many factors that cause RA.The most important factor is the lack of erythropoietin(EPO)and abnormal iron metabolism.Abnormal iron metabolism leads to insufficient or relative lack of iron.Hepcidin plays an important role in the regulation of iron metabolism abnormalities.This article mainly reviews the function of Hepcidin,related signal pathways and the relationship of Hepcidin in the occurrence and development of CKD,and provides a basis for clinical treatment of RA.

Key words： Hepcidin Chronic kidney disease Renal anemia Erythropoietin

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	WANG Fu-ju
	YU Li-xia▲

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WANG Fu-ju,YU Li-xia▲. Research progress of Hepcidin in the occurence and development of chronic kidney disease[J]. 中国当代医药, 2021, 28(17): 43-47.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I17/43

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