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2017 Vol. 24, No. 28
Published: 2017-10-08
4
Clinicopathological study of Fas-related death domain protein expression in breast cancer
WU Jia
Objective To explore the clinicopathological features of Fas-related death domain proteins expression in breast cancer.Methods From February 2013 to February 2017,148 cases of paraffin-embedded tissue specimens from patients undergone tumor surgeries were selected.There were benign breast lesions in 26 cases(group A),breast cancer without lymph node metastasis in 58 cases(group B),and breast cancer with lymph node metastasis in 64 cases(group C).All specimens were performed with immunohistochemical examinations in order to analyze the proteins expression of Fas-related death domain.Results It was detected that Fas-related death domain proteins were expressed in the intracytoplasm of breast cancer cells and epithelial cells of benign breast lesions.In group B,the expression of Fas-related death domain proteins was weak and dyeing range and depth were small compared with those in groups of A and C,which were in slight expression and deep dyeing.The positivity expression rates of Fas-related death domain proteins in groups of A,B,and C were 88.5%(23/26),46.6%(27/58),and 65.6%(42/64)respectively.The positivity expression rate in group A was higher than that in groups of B and C with statistical differences(P＜0.05).For breast cancer patients,lymph node metastasis and age with a definite diagnosis were associated with Fas-related death domain protein expression(P＜0.05).However,the clinical stage and histological type were not related to the expression of Fas-related death domain protein (P＞0.05).Conclusion The expression of Fas-related death domain proteins is closely related to the lymph node metastasis and age with a definite diagnosis of breast cancer,but it has nothing to do with the clinical stage and histological type,to which should be paid high attention.
2017 Vol. 24 (28): 4-6 [
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The effect of hyperbaric oxygen therapy and Notch signal channel blocker on proliferation and differentiation of neural stem cells in rats with traumatic brain injury
YANG Yong-kai;ZHANG Fan;WEI Hao;ZHOU Xiao-hui;CHEN Chun-mei;WANG Chun-hua;TU Xian-kun
Objective To observe the effects of hyperbaric oxygen therapy and DAPT on the proliferation and differentiation of endogenous neural stem cells after traumatic brain injury.Methods 100 adult Wistar rats were randomly divided into sham-operation group,traumatic brain injury group,DAPT group,hyperbaric oxygen therapy group and DMSO group.Animal models of craniocerebral trauma were made using the improved free-fall method in the rats.The proliferation and differentiation of neural stem cells of the DG brain tissue was detected by BrdU labeling fluorescence immunocytochemistry at the 7,14,21 d and 28 d after injury.Results The BrdU and nestin positive cells of the traumatic brain injury group,DAPT group and hyperbaric oxygen therapy group began to increase from the 7 d(14.2±1.3,11.4±1.7,22.3±1.5)to the 14 d after injury(9.6±0.7,6.9±2.1,13.8±1.4).Compared with the 14 d,the BrdU and nestin positive cells significantly increased 7 d after injury(P＜0.05).Compared with the traumatic brain injury group,the BrdU and nestin positive cells significantly decreased in the DAPT group 7 d and 14 d after injury(P＜0.05).Compared with the traumatic brain injury group,the BrdU and nestin positive cells significantly increased in the hyperbaric oxygen therapy group 7 d and 14 d after injury (P＜0.05).Conclusion Hyperbaric oxygen therapy can enhance the proliferation and differentiation of endogenous neural stem cells after traumatic brain injury.Notch signal channel blocker can restrain the proliferation and differentiation of endogenous neural stem cells after traumatic brain injury.
2017 Vol. 24 (28): 7-10 [
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Research progress on relationship between Helicobacter pylori infection and diabetic nephropathy
LI Min;WANG Yu-ling;LIU Lei
Diabetic nephropathy (DN)is one of the important microvascular lesions in diabetes,and it′s also one of the most common and refractory vascular complications in type 2 diabetes(T2DM),but its specific pathogenesis is not clear.Helicobacter pylori(Hp)is a kind of screw bacteria colonized in human gastrointestinal mucosa,Hp infection can cause acute or chronic immune inflammation,and it can lead to a variety of digestive diseases.In recent years,the relationship between Hp infection and parenteral diseases has been paid more and more attention by domestic and foreign scholars.It has been found that Hp infection may be one of the important causes of DN,this review will discuss the relationship between Hp infection and the occurrence and development of DN.If the exact relationship is confirmed,it will change the diagnosis and treatment of DN.
2017 Vol. 24 (28): 11-13 [
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190
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Study on the reasons of the Minor Cross-matching agglulination by Micro-column Gel way and its clinical significance
LI Miao-shan;WU Chang-lin;ZHOU Xue-min;DANG Xin-tang;ZHU Yi;SHAO Chao-peng
Objective To evaluate the agglulination reasons for the minor cross-matching,to provide reference for the safety of clinical blood transfusion.Methods Cases of patients with side crosss-matching agglulination were chosen from January 2013 to May 2016 in our hospital,according to the disease group,to investigate the correlation of the proportion of side cross-matching agglulination and the numbers of blood transfusion and the blood transfusion reaction.We had analysed the reasons of the side crossmatching agglulination by the antiglobulin test,antibodies identification,drug antibody screening and identification,and the size of RBC and morphology,combined with the clinical blood transfusion.Results 45 672 cases were investigated by micro-column gel way,ther were 325 cases side agglutination,the agglutination rate was 0.71%.The patients with side cross-matching agglulination mainly included haematology patients,ICU critical patients and emergency and burn patients.The agglulination rates of the haematology patients associated with the numbers of blood transfusions,there were positive correlation between the times of blood transfusion reaction and the times of blood transfusion(P＜0.05),but there were no relevance between the agglulination rates for the patients in the ICU and emergency room and the times of blood transfusion(P＞0.05).The reasons of side cross-matching agglulination mainly included,drugs antibodies,plasmas proteins,erythrocyte alloantibody of donor,the changes of the erythrocyte morphology,improper sample,the bad blood anticoagulation,the old red cell，insufficient washing cell,and so on.There were significant difference between the cases caused by immune and non immune factors in the side crosssmatching agglulination(P＜0.05).Conclusion The agglulination reasons of the side cross-matching have many types,the agglulination rates caused by non immune factors,are the highest in the clinical blood transfusion,which show low transfusion reaction rate and infusion inefficiency rate.But the side cross-matching agglulination cases caused by the imune factors easily lead to more transfusion reaction.and worse infusion efficiency.
2017 Vol. 24 (28): 14-17 [
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Application of laparoscopic cholecystectomy using the technique of nonseparation and non-disconnection of the trunk of the cystic artery in the treatment of acute calculous cholecystitis
LI Zheng-chen;LIU Yang-sui;ZHANG Xin-hui
Objective To investigate the safety and clinical efficacy of laparoscopic cholecystectomy using the technique of non-separation and non-disconnection of the trunk of the cystic artery in the treatment of acute calculous cholecystitis.Methods From October 2015 to March 2017,the clinical data of 84 patients undergone laparoscopic cholecystectomy due to acute calculous cholecystitis in our hospital were retrospectively analyzed.The age,sex,operation time,intraoperative amount of bleeding,hospital stay after surgery,and occurrence of postoperative complications were extracted.In observation group(n=42),laparoscopic cholecystectomy using the technique of non-separation and non-disconnection of the trunk of the cystic artery was adopted,while in the control group(n=42),regular laparoscopic cholecystectomy was used.Results Patients in the two groups were all successfully finished the operation without transfering to laparotomy.There was no significant difference in age，sex，operation time,or hospital stay after surgery between the two groups(P＞0.05).The bleeding during surgery in the observation group was less compared with that in the control group(t=4.75,P＜0.05）.The total incidence of postoperative complications was significantly lower in the observation group in comparison with that in the control group(t=7.26,P＜0.05）.Conclusion Application of laparoscopic cholecystectomy using the technique of non-separation and non-disconnection of the trunk of the cystic artery to treat acute calculous cholecystitis can effectively reduce the occurrence of bleeding during and after surgery as well as postoperative complications,which is worthy of promotion in clinic.
2017 Vol. 24 (28): 18-20 [
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Application of electric suction machine combined with automatic gastric lavage in gastric lavage in emergency poisoning patients
XU Dong-sheng;ZHANG Ye WANG;Zhong-xiang
Objective To explore the application of electric suction machine combined with automatic gastric lavage in gastric lavage in emergency poisoning patients.Methods From January 2016 to January 2017,100 patients with emergency poisoning were selected and randomly divided into control group and observation group,with 50 cases in each group.The control group was treated with artificial gastric lavage.The observation group was treated with electric suction machine automatic gastric lavage gastric lavage,compared the two groups of patients with gastric lavage operation time,clinical symptoms of remission time,gastric lavage residue,length of stay and adverse reactions occurred.Results The time of gastric lavage operation,the remission time of clinical symptoms,the residual amount of gastric lavage fluid and the length of hospital stay were better than those of the control group (P＜0.05).The total incidence of adverse reactions in the observation group (gastric tube blockage，aspiration，asphyxia,wash bleeding liquid)4.00%,lower than the control group(P＜0.05).Conclusion The use of electric suction machine combined with automatic gastric lavage machine in patients with emergency poisoning gastric lavage,can effectively shorten the time of gastric lavage and hospital stay,and can effectively reduce the occurrence of adverse reactions to the situation,it is worthy of widespread use.
2017 Vol. 24 (28): 21-23 [
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186
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Application of damage control surgery in the treatment of severe abdominal trauma in Plateau remote area
YANG Chun-hua;HUANG Wei
Objective To investigate the value of damage control surgery in the treatment of severe abdominal trauma in Plateau remote area.Methods 48 severe abdominal trauma patients from January 2012 to December 2016 in our hospital were selected as observation objects and retrospectively analyzed.Patients were divided into DCS group and control group according to different treatment method,and each group was 24 cases.DCS group was used damage control surgery,and the control group was used general surgery.The recovery time of postoperative blood coagulation function(PT,APTT),temperature recovery time,lactate clearance time,hospitalization time and postoperative complications were compared and analyzed between the two groups.Results The two groups were mainly caused by traffic injuries,and there was no significant difference in weight injuries，high-altitude falling injuries，stab injuries and crush injuries (P＞0.05).The averaged injury severity score(ISS)of the two groups was(41.26±4.46)scores,and the difference was not statistically significant(P＞0.05).PT and APTT recovery time,lactic acid clearance time and body temperature recovery time were significantly lower in the DCS group than those in the control group (P＜0.05).In terms of individual complications,the difference was not statistically significant between two groups(P＞0.05).The postoperative lung，abdominal cavity and adhesive intestinal obstruction infection in group DCS were significantly lower than those in the control group,the difference was statistically significant(P＜0.05).Conclusion Damage control surgery in the treatment of severe abdominal trauma in the remote areas with a high clinical value compared with conventional surgery,which can significantly shorten the blood coagulation function recovery time,clearance time of lactic acid and body temperature recovery time,and with low incidence of postoperative complications,and is worthy of promotion and application.
2017 Vol. 24 (28): 24-26转35 [
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Clinical study of high-dose Atorvastatin on peripheral blood nuclear factor kappa B in patients with acute coronary syndrome complicated with diabetes mellitus
ZENG Hui;LIU Jun-min;LIN Bo-li
Objective To explore the influence of high-dose Atorvastatin on peripheral blood nuclear factor-kappa B(NF-κB)in patients with acute coronary syndrome(ACS)complicated with diabetes mellitus(DM).Methods From June 2015 to May 2017,100 ACS patients complicated with DM admitted into our hospital were selected and evenly divided into control group (n=50)and experimental group (n=50)in random.Participants in both groups were provided with Atorvastatin for treatment,but with different doses.In the control group,the dose was 10 mg/d,while in the experimental group,the dose was 40 mg/d.The serum biochemical test and the expression and detection of NF-κB were performed before and 4 weeks after the experiment.In addition,the incidence of cardiovascular events was calculated.Results After therapy,the levels of NF-κB,hs-CRP,IL-6,and TNF-α in the two group were all decreased to some extent,and the decrease in the experimental group was more remarkable than that in the control group,which was displayed a statistical inter-group difference(P＜0.05).In the control group,the incidence of cardiovascular events was 20.00%,while 4.00%in the experimental group with a statistical difference(P＜0.05).Conclusion In the treatment of ACS complicated with DM,high-dose Atorvastatin can significantly inhibit NF-κB activity,attenuate inflammation reactions,relieve clinical symptoms,and reduce the incidence of cardiovascular events with an affirmative clinical value.
2017 Vol. 24 (28): 27-29 [
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Clinical study of Tirofiban used at different time on coronary blood flow and short-term prognosis for an interventional emergency treatment of acute myocardial infarction
HUANG Xi-liang
Objective To study the influence of Tirofiban used at different time on coronary blood flow and short-term prognosis for an interventional emergency treatment of acute myocardial infarction(ACIS).Methods From December 2014 to December 2016,92 patients with AMI admitted into the emergency of our hospital were selected,and they were divided into control group and observation group by a random number table.In the control group,Tirofiban was intravenously injected after surgery.In the observation group,Tirofiban was intravenously injected before surgery.The coronary TIMI blood flow grade,creatine kinase isoenzyme,left ventricular ejection fraction before and after intervention,complete falling rate of ST segment and the incidence of adverse cardiovascular event between the two groups were compred.Results The improve range of coronary TIMI blood flow grade,creatine kinase isoenzyme,left ventricular ejection fraction before and after treatment in the observation group were greater than that of the control group(P＜0.05).The complete falling rate of ST segment in the observation group was 60.9%,and it was higher than that in the control group accounting for 32.6%with a statistical difference(P＜0.05).The incidence of adverse cardiovascular event in the observation group was 4.3%,which was lower than that in the control group(23.9%)(P＜0.05),which was lower than that of the control group(P＜0.05).Conclusion The short-term prognosis of Tirofiban applied before operation on coronary blood flow and short-term prognosis for an interventional emergency treatment of acute myocardial infarction is more ideal,and has a more positive effect on the related indexes of coronary artery blood flow compared with that injected after surgery.
2017 Vol. 24 (28): 30-32 [
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Influence of biotinylated microfibrinopeptide modified IGF-1 on myosin gene expression in rabbits with myocardial infarction
HU Yun-hua;ZHANG Ming;MEI Zhi-liang;XIAO Zu-ke
Objective To study the influence of biotinylated microfibrinopeptide modified IGF-1 on myosin gene expression in rabbits with myocardial infarction.Methods A total of 28 healthy male New Zealand white rabbits were randomly divided into the control group,experimental group 1,experimental group 2,and experimental group 3,and there were 7 ones in each group.In the control group,rabbits were performed with thoracotomy but without ligation of left anterior descending branch of coronary artery.For experimental group 1,2,and 3,model of myocardial infarction in rabbits was established.After successful modeling,biotinylated microfibrinopeptide modified IGF-1 was injected in the experimental group 1.In the experimental group 2,biotinylated microfibrinopeptide IGF-1 without modification was injected.In the experimental group 3(myocardial infarction)and control group(without ligation),the same dose of normal saline was injected.The gene expression of myosin was determined 8 weeks after surgery.Results Compared with the control group,theexpression level of myosingene in the experimental group 3 was significantly decreased,but in the experimental group 1 and 2,the gene expression level were greatly increased(P＜0.05).The expression level of myosin gene in the experimental group 1 was significantly higher than that in the experimental group 2.Conclusion Acute myocardial infarction will attenuate the gene expression of myosin in rabitts.Both IGF-1 and biotinylated microfibrinopeptide modified IGF-1 can improve gene expression of myosin in rabbits with myocardial infarction,but the effect is better in the latter.
2017 Vol. 24 (28): 33-35 [
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Research on change of pulmonary arterial pressure in adult patients after occlusion of atrial septal defect
CAO Jun;ZHAO Li-li
Objective To analyze the change of pulmonary arterial pressure in adult patients after occlusion of atrial septal defect(ASD).Methods 25 patients with ASD treated in our hospital from April 2013 to April 2014 were selected,and they were given occlusion of ASD by using occluder under the monitoring of Trans-Thoracic Echocardiography(TTE).The pre-and post-occlusional change of pulmonary artery pressure,arterial blood gas and airway pressure fluctuation were analyzed.Results The post-occlusional pulmonary artery systolic pressure(PASP)and pulmonary artery diastolic pressure(PADP)of 25 ASD patients was(35.66±10.53)mmHg and(22.85±5.42)mmHg respectively,and it was lower than that of pre-occlusion[(46.90±8.49)mmHg and(29.93±5.36)mmHg]respectively(P＜0.01).Postoperative left ventricular stroke volume,left ventricular ejection fraction (except after 2 days operation)was significantly higher than the preoperative,and the right atrium diameter and the main pulmonary arterial pressure were lower than those before operation,after operation (except after 2 days operation),left ventricular eccentricity index and left ventricular L/D were significantly smaller than those before operation (P＜0.05).After 12 months of follow-up,the ventricular remodeling was continuously reversed.There were significant differences in the hemodynamic data between before operation and after 12 months operation (P＜0.05).Conclusion Occlusion of ASD in adult patients with ASD under the monitoring of TTE not only can effectively alleviate the right heart load,reduce the left ventricular eccentric index,relieve hemodynamic parameters,and improve hemodynamic indexes and reverse the process of heart remodeling at the same time,and the heart function of most patients return to normal level after 3 months operation.
2017 Vol. 24 (28): 36-38 [
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Application of Ivabradine in patients with stable angina pectoris complicated with chronic obstructive pulmonary disease
LI Song-biao;TAN Cui-yan
Objective To observe the application effect of Ivabradine in patients with stable angina pectoris complicated with chronic obstructive pulmonary disease (COPD).Methods From January 1,2014 to December 30,2016,42 patients with stable angina pectoris complicated with COPD were selected in our hospital.They were randomly divided into the routine treatment group and ivabradine group，with 21 cases in each group.Routine treatment was used in the former group and ivabradinewas added besides treatment in routine group.The application effect was compared between the two groups.Results After therapy,there was no statistical difference of pulmonary function indexes between the two groups(P＞0.05).In the ivabradine group,6-min walking distance and CAT score were both improved.The 24-hour average heart rate was significantly decreased as well as frequency of angina pectoris and doses of Nitroglycerin compared with those in the routine group with statistical differences(P＜0.05).Conclusion For patients with stable angina pectoris and COPD,Ivabradinecan applied can improve the patients′exercise tolerance and quality of life,and reduce the attack times of angina pectoris in a definite effect,which can be recommended.
2017 Vol. 24 (28): 39-41 [
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The influence of potassium magnesium aspartate combined Amiodarone on treatment of ventricular arrhythmia caused by coronary heart disease and PR interval and QRS duration of the electrocardiogram
WEN Rui;LIU Ke-quan;HE Min-hong
Objective To study the influence of potassium magnesium aspartate combined Amiodarone on treatment of ventricular arrhythmia caused by coronary heart disease and PR interval and QRS duration of the electrocardiogram.Methods 54 patients of coronary heart disease with ventricular arrhythmia treated in our hospital from December 2015 to December 2016 were selected as the research objects，according to the treatment method，which were divided into the research group(n=27)and the control group(n=27).The control group were given Amiodarone,while the research group was given potassium magnesium aspartate combined Amiodarone;the treatment effect of ventricular arrhythmia andheartfunction,adverse reaction occurrence and electrocardiogram PR interval and QRS duration of two groups were compared.Results The treatment effective rate of ventricular arrhythmia of the research group was 92.6%,which was greatly higher than 66.7%of the control group,and the treatment effective rate of cardiac function of the research group was 88.9%,that was significantly higher than 63.0%of the control group，and the differences were both statistically significant(P＜0.05);The difference between PR interval and QRS duration of two groups before the treatment were not statistically significant(P＞0.05),but PR interval of two groups after the treatmentwas significantly longer than that before the treatment,and QRS duration of two groups was significantly shorter than that before the treatment,and the differences were both statistically significant(P＜0.05),howeverthe difference between PR interval and QRS duration of two groups after the treatment were not statistically significant(P＞0.05);The total adverse reaction incidencewas 25.9%,obviously less than 7.4%of the control group,and the difference was statistically significant(P＜0.05).Conclusion Potassium magnesium aspartate combined Amiodarone in treatment of ventricular arrhythmia caused by coronary heartdisease on PR interval and QRS duration of the electrocardiogramhave good treatment effect,which not only can effectively control the ventricul ararrhythmia,but also improve the patient′s heart function,and influence the PR interval and QRS duration of electrocardiogram very little,and cause less adverse reactions.
2017 Vol. 24 (28): 42-44 [
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Effect of early rehabilitation training on the recovery of post-PCI patients
LONG Ben-dong;LIN An-xiao;TENG Xuan;LIANG Mu
Objective To observe the effect of early rehabilitation training on the recovery of post-PCI(percutaneous coronary intervention)patients.Methods Altogether 100 patients who underwent PCI in our hospital from January 2015 to January 2016 were selected and randomly divided according to different rehabilitation training approaches into two groups,with 50 cases in each group.Patients who underwent conventional rehabilitation training were grouped as control group;while patients who accepted early rehabilitation training were grouped as observation group.The LOS (length of stay),recovery of cardiac functions,incidence of adverse reactions and QOL(quality of life)score were compared between the two groups of post-PCI patients.Results The LOS[(13.14±2.72）)d],cardiac function indexes at postoperative 1 year,incidence of adverse reactions (2%)and QOL score of observation group were significantly better than those of control group,with statistically significant difference (P＜0.05).Conclusion Application of early rehabilitation training in post-PCI patients can significantly improve the recovery effect of cardiac functions and reduce the incidence of complication,which has important significance to enhance patients′quality of life and is worthy of clinical popularization and application.
2017 Vol. 24 (28): 45-47 [
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Implementation and elevation of clinical pathway of ST-segment elevation acute coronary syndrome
ZHOU Xu-feng;XIE Dong-ming;JU Yan-juan;ZHONG Wen-ting;ZHU Jin-hai
Objective To explore the effect of the clinical approach of ST-segment elevation acute coronary syndrome.Methods 120 patients weres selected as research subjects,who was in ST-segment elevation acute coronary syndrome in our hospital from January 2013 to December 2016.The patients were divided into control group and CP group according to before and after the implementation of standardized rescue,with 60 cases in each group.For the control group to take routine treatment,CP group was based on our hospital′s own STE-ACS clinical path for diagnosis and treatment.The hospitalization time,average hospitalization cost,average drug cost and satisfaction degree were choosed as an evaluation indexs.Results CP group effective rate was 95.0%higher than the control group′s 86.7%(P＜0.05).The average hospital stay was(10.97±2.11)day in the CP group and(13.32±25)day in the control group(P＜0.05).The average cost of CP group was(7224.28±106.23)yuan,and the average cost of the control group was(8319.23±16.35)yuan(P＜0.05).CP group′s satisfaction was 96.67%,control group′s satisfaction was 81.67%(P＜0.05);CP group′s adverse reaction rate was 1.67%,the control group was 6.67%(P＜0.05).Conclusion Clinical application of the clinical pathway in patients with ST-segment elevation acute coronary syndrome(STE-ACS)was expected to be satisfactory.Not only improve the quality of medical care,but also shorten the number of hospital days,reduce the cost of hospitalization,in line with China′s national conditions.CP can be better improve the quality of medical care,protect medical security,standard medical charges,save health resources,improve patient satisfaction,Can be widely used in clinical practice.
2017 Vol. 24 (28): 48-50 [
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Clinical curative effect observation of rTMS combined with cognitive training in the treatment of vascular cognitive impairment
XU Jing-jing;CAO Zhong-yao;ZHANG Qing-hua
Objective To observe the clinical effect of rTMS combined with cognitive training in the treatment of VCI.Methods A total of 91 patients with VCI who received rehabilitation treatment in our hospital from July 2015 to June 2016 were enrolled.The treatment group was treated with rTMS combined with cognitive training.The control group was given only cognitive training.Application of MoCA and LOTCA in patient`s cognitive assessment.Results After treatment,the MoCA total scores and individual items(execution,abstract,memory and orientation)of the treatment group were higher than those in the control group,the differences were statistically significant(P＜0.05).The total score of LOTCA and the individual items(orientation,perception,thinking)in the treatment group were higher than those in the control group,the differences were statistically significant(P＜0.05).After treatment scores of MoCA and LOTCA scales were both increased in the two groups compared with before treatment,the differences were statistically significant(P＜0.01);After treatment,in the LOTCA individual,the scores of perception,thinking and visual and spatial perception in the control group were higher than before treatment,the differences were statistically significant(P＜0.01);in the MoCA single item,the scores of other items expectnaming in the control group were higher than those before the treatment,and the differences were statistically significant(P＜0.01);the individual itemes scores of the treatment group after treatment were higher than those before treatment,the differences were stastistically significant(P＜0.01).Conclusion rTMS combined with cognitive training can improve cognitive function and the quality of life of patients with VCI.
2017 Vol. 24 (28): 51-54 [
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Research on mismatch negativity wave in patients with mild cognitive impairment
WANG Rong-ye;WU Dong-hui;LAI Wen-tao;XIE Guo-hua;FENG Fei;ZHAO Jie
Objective To explore the diagnostic value of event-related potential mismatch negativity (MMN)for mild cognitive impairment(MCI).Methods From April to September in 2015,24 patients with MCI(MCI group)treated in our memory clinic were selected.At the same period,21 normal old people(NC group)with matched sex,age,and educational levels were recruited.The cognitive function in two groups was evaluated by mini-mental state examination(MMSE).MMN was compared and analyzed in MCI patients and participants in normal control group by event-relatedexamination.Results In MCI group,the latent period and amplitude of MMN in three electrode points of Fz,Cz,and Pz were not displayed statistical differences compared with the normal control group (P＞0.05).Conclusion Auditory MMN(AMMN)in MCI patients may be not in significant abnormality.
2017 Vol. 24 (28): 55-57 [
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194
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A study of the attributional style in patients with schizophrenics accompanied with persecutory delusion
SHENG Yu-shan
Objective To explore the attributional style in patients with schizophrenics accompanied with persecutory delusion.Methods From May 2015 to May 2016,98 patients with schizophrenics accompanied with persecutory delusion admitted into our hospital for treatment were selected as observation group.Meanwhile,another group of 98 healthy adults for physical examinations were chosen as control group.The schizophrenia symptom attribution questionnaire and brief psychiatric rating scale were used to evaluate the characteristics of symptom attribution as well as analyze the correlation between severity of symptoms and attribution.Results The score of the internal-external(locus of control),local-integral(integrity),and controllable-uncontrollable (controllability)were all displayed statistical differences in the two groups(P＜0.05).In the observation group,the internal-external dimension was associated with the age of first onset,course of disease,and hostile factor(P＜0.05).The temporary-permanent dimension was influenced by frequency of hospitalization,anxiety and depression factors,and hysteresis factor(P＜0.05).The local-global dimension was affected by the hostile factor(P＜0.05).Conclusion The characteristics of attributional style in patients with schizophrenics accompanied with persecutory delusion are prone to be external,holistic,and uncontrollable.
2017 Vol. 24 (28): 58-60 [
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Influence of limbs coordination training on stroke patients with unilateral neglect
LIN YiLIN;Jin-lai;LUO Xing-wen
Objective To observe the effect of limbs coordination training on the functional recovery of stroke patients with unilateral neglect.Methods Altogether 40 stroke patients with unilateral neglect hospitalized in department of neurology and department of rehabilitation of our hospital from May 2013 to May 2015 were randomly divided into treatment group and control group,and there were 20 cases in each group.Treatment group was treated with routine rehabilitation combined with limbs coordination training,while control group was treated with routine rehabilitation treatment.Catherine-Bergego scale(CBS)and simplified Fugl-Meyer assessment(FMA)were used before and after 8 weeks treatment for evaluation.Results After 8 weeks treatment,CBS and FMA score of two groups had statistically significant difference in comparison with before treatment(P＜0.05),CBS score of treatment group was lower than that of control group(P＜0.05),FMA score of treatment group was higher than that of control group(P＜0.05).Conclusion Combination of limbs coordination training and routine rehabilitation treatment can improve the symptoms of patients with unilateral neglect so as to further improve the extremity motor function of patients.
2017 Vol. 24 (28): 61-63 [
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Influence of hospital-community integrated prevention,treatment,and nursing on rehabilitation of community-based patients with severe psychoses
YU Wei;LI Hai-yun;CHEN Zi-lang
Objective To explore the influence of hospital-community integrated prevention,treatment,and nursing on rehabilitation of community-based patients with severe psychoses.Methods From March 2015 to March 2016,120 patients with severe psychosis having been “cured” in our hospital and discharged from our hospital were divided into research group (n=60)and control group (n=60)in random.In the control group,psychotropic drugs were used,while in the research group,on the basis of the control group,thehospital-community integrated prevention,treatment,and nursing for 1 year was added.PANSS-EC score and questionnaire were used to evaluate and compare.Results After 1 year intervention,the score of PANSS-EC was(6.3±1.71)points in the research group,and it was much lower than that in the control group(12.1±1.3)points.In the research group,monitoring rate,rate of regular taking medicine,andsocial participation rate were all much higher than those in control group(P＜0.01).In the research group,the recurrence rate was 23.33%,and it was greatly lower than that in the control group (100.00%)(P＜0.01).In the research group,the rate of making troubles was 6.66%,and it was significantly lower than that in the control group accounting(25.00)(P＜0.01).Conclusion The hospital-community integrated prevention,treatment,and nursing can relieve mental symptoms,improve the regular taking medicine rate,socialparticipancy rate,as well as family custody rate of patients,and decrease the disease recurrence and the occurrence of making troubles,which is of great significance on reducing social harm and bettering social function.
2017 Vol. 24 (28): 64-66转69 [
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Effect comparison of bilateral flap resection and improved craniotomy with large flap resection in the treatment of acute craniocerebral injury
JI Kang-rong;LI Kang-cheng;CHEN Qin
Objective To investigate the effect of bilateral flap resection and improved craniotomy with large flap resection in the treatment of acute craniocerebral injury.Methods 84 patients with acute craniocerebral injury treated in our hospital from December 2013 to December 2016 were selected.According to the random number method,the patients were divided into observation group and control group,with 42 patients in each group.The patients in the control group were treated with modified large bone flap craniotomy,and the observation group was treated with bilateral flap resection craniectomy.GCS score before and after treatment,the intracranial pressure before treatment and 3 d and 7 d after treatment and the prognosis were compared between the two groups.Results GCS score in the observation group was obviously higher than that in the control group after treatment,and the difference was statistically significant(P＜0.05).The intracranial pressure in the observation group was obviously lower than that in the control group after 3 d and 7 d treatment,and the difference was statistically significant(P＜0.05).The prognosis in the observation group was better than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion Compared with improved craniotomy with large flap resection,the application of bilateral bone flap resection craniotomy in the treatment of acute craniocerebral injury is more significant,which can reduce the intracranial pressure of patients.During the treatment,the possibility of deterioration is the lower,which is more conducive to promoting the recovery process of patients and therefore is worthy of clinical application and promotion.
2017 Vol. 24 (28): 67-69 [
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161
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Comparison of the efficacy and safety of Oxazepam and Diazepam in alternative treatment of alcohol dependence
HUANG Long-xing;LI Ya-hui
Objective To compare the efficacy and safety of Oxazepam and Diazepam in alcohol-dependent replacement therapy.Methods A total of 78 patients with alcohol dependence from January 2015 to May 2017 treated in our hospital were selected as study subjects and they were randomly divided into the two groups and there were 39 cases in each group.The Diazepam group was treated with Diazepam and the Oxazepam group was treated with Oxazepam.The total effective rate and total incidence of adverse reactions such as excessive sedation,urinary incontinence and so on,and the score of Hamilton Anxiety scale,Hamilton Depression scale and the withdrawal response scale were compared before and after the intervention between the two groups.Results The total effective rate in the Oxazepam group was higher than that in the Diazepam group (P＜0.05).The total incidence of adverse reactions such as excessive sedation and urinary incontinence and so on in the Oxazepam group was lower than that in the Diazepam group (P＜0.05).The score of Hamilton Anxiety scale,Hamilton Depression scale and abstinence response scale had no statistical difference between the two groups before intervention (P＞0.05),the score of Hamilton anxiety scale,Hamilton Depression scale and withdrawal response scale were better than those of the Diazepam group (P＜0.05).Conclusion Oxazepam is superior to Diazepam in the treatment of alcohol dependence,which can reduce the incidence of adverse reactions,improve the clinical symptoms and relieve the negative emotion.
2017 Vol. 24 (28): 70-72 [
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213
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Effect comparison of small bone window craniotomy and large bone flap craniotomy in the treatment of hypertensive intracerebral hemorrhage
XU Jin-fa;ZHUANG Yi-jie;ZHENG Yan-xuan
Objective To compare the clinical effect of small bone window craniotomy and large bone flap craniotomy in the treatment of hypertensive intracerebral hemorrhage.Methods 90 patients with hypertensive intracerebral hemorrhage admitted into our hospital from March 2013 to March 2016 were selected as the study subjects.The patients were randomly divided into the control group and the study group,and there were 45 cases in each group and they were respectively given traditional large bone flap craniotomy and small bone window craniotomy.The incision length,intraoperative blood loss,postoperative cerebrospinal fluid leakage,operation time,average length of hospital stay and the incidence rate of postoperative complications were compared between the two groups.Results The incision length,operation time and average length of stay in the study group were significantly shorter than those in the control group,and the difference was statistically significant(P＜0.05).The intraoperative blood loss in the study group was significantly lower than that in the control group(P＜0.05).The total clinical effective rate in the study group was 91.11%,which was significantly higher than that of 71.11%in the control group,and the difference was statistically significant(P＜0.05).The incidence rate of total complications was 15.56%,which was significantly better than the control group(42.22%),and the difference was statistically significant(P＜0.05).Conclusion Small bone window craniotomy and traditional large bone flap craniotomy can both effectively treat the hypertensive intracerebral hemorrhage,but compared with large bone flap craniotomy,small bone window craniotomy has a good clinical efficacy.The trauma is small,the operation time is short,the incidence of postoperative complications and mortality are low,and it is safe and reliable.
2017 Vol. 24 (28): 73-75 [
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Relationship between fall and aortic calcification of hemodialysis patients
SHEN Jiang-shan;ZHOU Yang;YIN Jin–feng
Objective To investigate the relationship between fall and aortic calcification of hemodialysis patients.Methods 80 cases of hemodialysis patients in blood purification center of our hospital from January 2016 to January 2017 were selected as research objects,these patients were divided into the aortic calcification group (n=17)and the non-aortic calcification group(n=63)according to aortic calcification occurred.The data of the two groups were recorded,such as sexes,ages,ages of dialysis,primary diseases and so on.The occurrences of falls was observed,the causes were analyzed,and the results were observed,then the incidences of falls of the two groups was statistically analyzed.Results The incidence of fall of the aortic calcification group was 88.2%(15/17),which was significantly higher than 22.2%(14/63)of the non aortic calcification group(P＜0.05),the main reasons of the fall occurred were hypotension,arrhythmia,decreased exercise tolerance,occurs mainly in the time after dialysis,the consequences was skin contusion.Conclusion The incidence of falls of hemodialysis patients is significantly related to aortic calcification,the clinical measures should take targeted measures to reduce the incidence of falls of hemodialysis patients to the minimum.
2017 Vol. 24 (28): 76-78 [
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127
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Application value of C-reactive protein level in predicting spontaneous stone passage in patients with distal ureteral stones
LI Fei-yang;LV Jian-lin
Objective To evaluate the application value of the C-reactive protein(CRP)level in predicting spontaneous stone passage in patients with 5 to 9 mm distal ureteral stones.Methods Clinical data of patients with distal ureteral stones who met the inclusion criteria from December 2014 to December 2015 were collected.CRP levels were measured.After 5 weeks,according to whether the spontaneous stone passage,the patients were divided into the stone discharging group and the stone undischarged group.The receiver operating characteristic(ROC)curve was drawn to determine the optimal cut-off values of CRP for predicting spontaneous stone passage.Results A total of 348 patients completed the study.Spontaneous stone passage was observed in 224 patients,the stone discharging rate was 53.8%.ROC analysis resulted in an area under the curve of 0.882 for serum CRP.Using ROC,a cut-off point of 8.5 mg/L for CRP yieldedappearedoptimalforpredictionofspontaneousuretericstoneexpulsion(sensitivitywas76.6%,specificitywas 86.2%).In the proportion of CRP＞8.5 mg/L,the stone undischarged group was significantly higher than that the stone discharging group,with significant statistical difference(P＜0.05).In the stone discharging group,time to spontaneous stone passage in patients with a CRP level less than or equal to 8.5 mg/L was shorter than that the CRP Level over 8.5 mg/L,the number of episodes of pain and the visual analogue scale(VAS)score were significantly less than that with a CRP level over 8.5 mg/L(P＜0.05).Conclusion CRP levels is useful for predicting.When CRP levels are greater than 8.5 mg/L,move aggressive interventions techniques should be considered.
2017 Vol. 24 (28): 79-82 [
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151
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Application analysis of Alprostadil Injection in elderly acute renal injury
BIAN Xiao-yan;GONG Chun-shui;LIANG Meng;GU Xiao-ling;SUN Qi
Objective To analyze the application effect of Alprostadil Injection on acute renal injury in the elderly.Methods From January 2015 to January 2017,98 patients with acute renal injury in our hospital were selected and randomly divided into the control group and the study group,49 cases in each group.The control group was given conventional specialist treatment,the study group was treated with Alprostadil Injection on the basis of the control group.The levels of BUN,SCr,NAG,β2-MG before and after treatment and the therapeutic effect,oliguria duration,SCr recovery time were compared between the two groups.Results There was no significant difference in the levels of BUN,SCr,NAG and β2-MG between the two groups(P＞0.05).The levels of BUN,SCr,NAG and β2-MG in the two groups after treatment was lower than that before treatment,the levels of BUN,SCr,NAG and β2-MG in the study group after treatment was lower than that in the control group,with significant difference (P＜0.05).The total effective rate of the study group was 91.84%,which was significantly higher than that of the control group (75.51%),with significant difference(χ2=4.780,P=0.029).The oliguria duration,SCr recovery time in the study group was (5.4±2.0),(7.2±2.9)days,respectively,which was significantly shorter than that in the control group[(6.9±2.0),(9.5±4.0)days],with significant difference(P＜0.05).Conclusion The application effect of Alprostadil Injection in acute renal injury in elderly patients is remarkable,which is worthy of promotion and application.
2017 Vol. 24 (28): 83-85 [
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Comparison of the efficacy of PKRP and TURP in the treatment of benign prostatic hyperplasia
XU Wei-jie;LI Wen-huan
Objective To investigate the clinical effect of plasmakinetic resection for prostate (PKRP)and transurethral resection of prostate (TURP)in the treatment of benign prostatic hyperplasia.Methods 100 cases of benign prostatic hyperplasia patients in our hospital from January to December in 2016 were selected and randomly divided into the control group and the study group,with 50 cases in each group.The control group was treated with TURP,and the study group was treated with PKRP.The intraoperative bleeding volume,operation time,bladder irrigation time,indwelling catheter time,hospitalization time,international prostate symptom score,quality of life score,maximum urinary flow rate(Qmax)and the incidence of complications in the two groups were compared.Results The intraoperative blood loss in the study group was significantly less than that in the control group,and the operation time,bladder irrigation time,catheter indwelling time and hospitalization time in the study group were significantly shorter than those in the control group,with significant difference(P＜0.05).The incidence of complications in the study group was 14.00%,which was significantly lower than that in the control group(44.00%),with significant difference(P＜0.05).There was no significant difference between the two groups in the international prostate symptom score,quality of life score and Qmax(P＞0.05).Conclusion The clinical effect of PKRP and TURP in the treatment of benign prostatic hyperplasia is basically similar,but PKRP treatment is less damage to patients,recovery rate is faster,and the incidence of complications is low.
2017 Vol. 24 (28): 86-88 [
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Effect observation of immunosuppressive therapy combined with hemodialysis in the treatment of patients with primary nephrotic syndrome complicated with acute renal failure
LU Ya-liang
Objective To investigate the clinical efficacy of immunosuppressive agents combined with hemodialysis in the treatment of patients with primary nephrotic syndrome complicated with acute renal failure.Methods From February 2015 to January 2017,60 patients with primary nephrotic syndrome complicated with acute renal failure in our hospital were selected as the study subjects,the improvement of the level of urinary protein,serum creatinine,urea nitrogen and serum albumin after treatment with immunosuppressant combined with hemodialysis and the clinical therapeutic effect were compared.Results The effective rate of clinical treatment was 98.3%in 60 patients after treatment,and the levels of urinary protein,serum creatinine,blood urea nitrogen and plasma albumin after treatment were better than that before treatment,with significant difference (P＜0.05).Conclusion Immunosuppressive therapy combined with hemodialysis is applied to the clinical treatment of patients with primary nephrotic syndrome complicated with acute renal failure,it can effectively improve the renal function of patients and improve the clinical therapeutic effect of patients.It is worthy of clinical promotion and application.
2017 Vol. 24 (28): 89-91 [
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Study on clinical application effect of Nephritis Rehabilitation Tablets in the treatment of glomerulonephritis
YANG Xue-hua;LEI Xiao-qing2
Objective To investigate the clinical application effect of Nephritis Rehabilitation Tablets in the treatment of glomerulonephritis.Methods Altogether 60 cases of glomerulonephritis patients who were treated in our hospital from February 23 in 2015 to February 23 in 2016 were selected and divided into the control group and the observation group according to the drawing lots,with 30 cases in each group.Valsartan and Nephritis Rehabilitation Tablets were applied respectively to the control group and observation group,then,patients′plasma albumin,cholesterol,creatinine,urea nitrogen and urine protein,the total effective rate,the incidence rate of adverse events and recurrence rate of the two groups were compared.Results The level of urea nitrogen,cholesterol,urine protein,the incidence rate of adverse events and the recurrence rate of the observation group were (6.12±0.36)mmol/L,(2.45±1.74)mmol/L,(0.18±0.12)g/24 h,3.33%and 3.33%,which were lower than those the control group′s (7.95±0.43)mmol/L,(3.95±1.43)mmol/L,(1.28±0.54)g/24 h,36.67%and 33.33%;the level of creatinine,plasma albumin and the total effective rate of the observation group were(63.45±2.13)μmol/L,(34.12±1.29)g/L and 96.67%,which were higher than those of the control group′s (61.74±1.32)μmol/L,(29.51±2.33)g/L and 63.33%,with significant difference(P＜0.05).Conclusion The treatment of glomerulonephritis patients with Nephritis Rehabilitation Tablets can improve the medication safety and long-term efficacy.
2017 Vol. 24 (28): 92-94 [
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Effect of modified external sheath pneumatic ballistic lithotripsy via resectoscope in the treatment of elderly bladder stones
SANG Hai-ming;GUO Zhen-yuan;SUN Yun;ZHU Yong;LENG Mei
Objective To study the clinical effect of modified external sheath pneumatic ballistic lithotripsy via resectoscope in the treatment of elderly bladder stones.Methods 102 patients with bladder stones who were admitted to our hospital from April 2016 to April 2017 were selected as the observation subjects.They were randomly divided into observation group and control group according to the random number table,with 51 patients in each group.The control group was given pneumatic ballistic lithotripsy under nephroscope,and the observation group was given modified external sheath-assisted pneumatic ballistic lithotripsy under nephroscope via resectoscope.The efficacy,the removal rate of stones,and complications were compared between the two groups.Results The operation time and length of hospital stay were significantly shorter in the observation group than those in the control group,the postoperative analgesic dose was less than that in the control group,the levels of inflammatory factors in the peripheral blood such as TNF-α and CRP 3 d after surgery were significantly higher than those in the control group,the differences were statistically significant(P＜0.01);there was no statistically significant difference in VAS and VRS scores between the two groups before operation (P＞0.05);postoperative VAS and VRS scores were significantly lower than those in the control group;there was no statistically significant difference in the incidence rate of complications between the two groups (P＞0.05).Conclusion The efficacy of modified external sheath-assisted pneumatic ballistic lithotripsy under nephroscope via resectoscope in the treatment of elderly bladder stones is better than that in the pneumatic ballistic lithotripsy under nephroscope,which is worthy of application.
2017 Vol. 24 (28): 95-97 [
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Clinical effect study of bamboo splint system in the treatment of distal radius fractures
WU Dong-ying;LIU Han-min;ZENG Fu-ying;ZHONG Wei-jian;HONG Zhong
Objective To explore the clinical effect of bamboo splint system in the treatment of distal radius fractures.Methods A total of 420 patients with distal radius fractures in our hospital and the First People′s Hospital of Nankang District from January 2015 to February 2017 were selected and randomly divided into the control group and the observation group,210 cases in each group.In the observation group,bamboo splint system was used,while in the control group,plaster slab for fixed treatment was adopted.The efficacy from both imaging and clinic function were compared in the two groups.Results The excellent and good rate of imaging in the observation group was 96.19%,which was higher than 86.67%in the control group,with significant difference(P＜0.05).The excellent and good rate of function score in 6 months after surgery in the observation group was 89.52%,which was higher than 73.81%in the control group,with significant difference(P＜0.05).Conclusion For patients with distal radius fractures,bamboo splint system is extremely safe and effective.It can promote the fracture healing and improve the clinical function score,which is worthy of promotion.
2017 Vol. 24 (28): 98-100 [
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Effect of Endobutton plate reconstruction of coracoclavicular ligament in the treatment of acromioclavicular joint dislocation
MIN Zhi-rong
Objective To analyze the clinical effect of Endobutton plate reconstruction of coracoclavicular ligament in the treatment of acromioclavicular joint dislocation.Methods From September 2015 to January 2017,76 patients with acromioclavicular joint dislocation admitted into our hospital were selected and randomly divided into the control group and the experimental group,38 cases in each group.The patients in the control group were provided with clavicular hook plate for internal fixation.The patients in the experimental group were given the Endobutton plate reconstruction of coracoclavicular ligament for the treatment.The shoulder joint JOA score,acromioclavicular joint VAS score,and score of should joint function after surgery were compared between the two groups.Results The JOA score in the experimental group after surgery was lower than that in the control group,and the score of VAS in the experimental group after surgery was higher than that of the control group,the evaluation of shoulder function in the experimental group was better than that of the control group,with significant difference(P＜0.05).Conclusion In the treatment of acromioclavicular joint dislocation,Endobutton plate reconstruction of coracoclavicular ligament can obtain a remarkable effect at advantages of simple performance,mild trauma for patients,and early recovery of functional exercise,which is worthy of promotion and application.
2017 Vol. 24 (28): 101-103 [
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Observation of the effect of locking plate fixation combined with medication in the treatment of osteoporotic intertrochanteric fracture
YUAN Zhong;HU Jun;XIONG Guo-hui
Objective To investigate the clinical efficacy of locking plate fixation combined with medication in the treatment of osteoporotic intertrochanteric fracture.Methods Altogether 80 patients with osteoporotic intertrochanteric fracture who were treated in our hospital from January 2015 to February 2016 were selected and randomly divided into the control group and the observation group,each with 40 cases.The control group was treated with locking plate fixation alone,and the observation group was treated with locking plate fixation combined with anti-osteoporosis drugs.The clinical efficacy of the two groups were compared.Results The start time of postoperative weight-bearing exercise and fracture healing time of the observation group were shorter than those of the control group,with significant difference (P＜0.05);The total excellent and good rate of joint function of the observation group at post-operative 12 months was 97.50%,which was higher than that of the control group(82.50%),with significant difference(P＜0.05).The bone mineral density of femoral neck and lumbar spine of the observation group was higher than that of the control group,with significant difference(P＜0.05).Conclusion The effect of combination of locking plate fixation and medication demonstrates in the treatment of osteoporotic intertrochanteric fracture is effective,which can quickly recover and improve bone density,it is worthy of promotion nd application.
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Effect observation of pedicle screw fixation combined with transpedicular bone grafting in the treatment of thoracolumbar fractures
XIE Qing-hua;CHEN Zhong-xian;FU Zhao-zong;LIU Yi-tao;XUE Zhong-lin
Objective To explore the clinical efficacy of pedicle screw fixation combined with transpedicular bone grafting in the treatment of thoracolumbar fractures.Methods Clinical data of 109 cases with thoracolumbar fracture from September 2011 to August 2015 in our hospital were retrospectively analyzed,all patients were divided into group A(49 cases)and group B (60 cases)according to different treatment methods.Group A was treated with simple pedicle screw fixation,and group B was treated with the pedicle screw fixation of the fractured vertebra combined with transpedicular bone grafting of the injured vertebra.All patients were followed up for 8-29 months,the mean follow-up was 15.1 months.The compression ratio of the leading edge height of the injured vertebra,the adjacent vertebral Cobb angle in digital radiography (DR)preoperative,postoperative and final follow-up in the two groups were compared.Operation time,blood loss and complications in the two groups were recorded.Results The operation time of group B was longer than that of group A,and the amount of bleeding of group B was more than that of group A,with significant difference(P＜0.05).The compression ratio of the leading edge height of the injured vertebra after operation and final follow-up of the two groups was greater than that before operation,and the angle of Cobb after operation and final follow-up of the two groups was smaller than that before operation,with significant difference(P＜0.05).The compression ratio of the leading edge height of the injured vertebra final follow-up of group A was smaller than that after operation,and the angle of Cobb final follow-up of group A was greater than that after operation,with significant difference (P＜0.05).There was no significant difference in the compression ratio of the leading edge height of the injured vertebra and the angle of Cobb of group B between final follow-up and after operation (P＞0.05).There was no significant difference in the compression ratio of the leading edge height of the injured vertebra and the angle of Cobb before operation and after operation between the two groups(P＞0.05).The compression ratio of the leading edge height of the injured vertebra final follow-up in group B was greater than that in group A,and the angle of Cobb final follow-up in group B was smaller than that of group A,with significant difference(P＜0.05).1 case nail was broken in group A,and 1 case loss of height of the vertebral column in group A,with symptoms of nerve compression and needed reoperation.There is no broken nail and loss of height of the vertebral column in group B.Conclusion In pedicle screw fixation combined with transpedicular bone grafting,the pedicle screw can effectively restore vertebral height,correct kyphosis angle;at the same time,combined with transpedicular bone grafting can reduce the complications such as long-term screw loosening,broken nail and vertebral height,Cobb angle loss and so on.
2017 Vol. 24 (28): 107-110 [
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Application value of belt loop button plate in the treatment of TossyⅢtype acromioclavicular joint dislocation
CAI Shi-jian;ZHONG Zhi-gang;ZHAO Zi-jian
Objective To analyze the application value of belt loop button plate in the treatment of TossyⅢtype acromioclavicular joint dislocation.Methods 36 patients with TossyⅢtype acromioclavicular dislocation who were admitted to our hospital from August 2014 to October 2016 were selected and divided into the experimental group and the control group according to the envelope randomization method,18 cases in each group.The patients in the experimental group were given belt loop button plate for treatment,and the patients in the control group were given clavicular hook plate fixation.The therapeutic effect was compared between the two groups of patients.Results There were no significant differences in the intraoperative blood loss,length of surgery and length of stay between the two groups(P＞0.05).In the experimental group,the degree of activity of anteflexion,the degree of activity of abduction and the Constant score were significantly better than those in the control group,the recovery time was significantly shorter than that in the control group,with significant difference(P＜0.05);the excellent and good rates in the experimental group was 94.44%,which was higher than 72.22%in the conventional group,with significant difference (P＜0.05).Conclusion For the patients with TossyⅢtype acromioclavicular joint dislocation,the belt loop button plate has less trauma and is conducive to the early recovery of patients′joint function.The excellent and good rate of treatment is high,which is worthy of practice and promotion.
2017 Vol. 24 (28): 111-113 [
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Characteristics and surgical curative effect observation of hyperextension injury of cervical spinal cord without fracture or dislocation
LI Dong;CHANG Zhi-yong;CAI Ping;GENG Ze;CHEN Gang;LI Kai-hua
Objective To analyze the characteristics of hyperextension injury of cervical spinal cord without fracture or dislocation and to evaluate the effect of surgical curative effect.Methods 15 cases of hyperextension injury of cervical spinal cord without fracture or dislocation treated surgically in our hospital from February 2013 to May 2015 were retrospectively reviewed.Neurological impairment and improvement were assessed using the ASIA system.Results All 15 patients were hyperextension injury.All patients were followed up for 14-41 months,with an average of(22.4±8.6)months.Preoperative ASIA rating showed that there were 3 cases in grade B,6 cases in grade C,and 6 cases in grade D.At the last follow-up,1 case was grade C,7 cases were grade D,7 cases were grade E.The improvement was 0.7 at 1 weeks after surgery in the ASIA rating,and the improvement was 0.8 at 3 months after surgery,the improvement was 1.2 at six months,1 years and the last follow-up after surgery.Conclusion Spinal stenosis is the main pathological basis of hyperextension injury of cervical spinal cord without fracture or dislocation,hyperextension injury is the direct cause of spinal cord injury,incomplete spinal cord injury is its clinical features.For significant spinal stenosis,spinal cord compression,cervical spinal cord edema in patients with degeneration,surgical treatment effect is significant.
2017 Vol. 24 (28): 114-116转119 [
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Effect of Live Combined Bacillus Subtilis and Enterococcus Faecium Granules with Multivitamines on mannan-binding protein level of the infants with rotavirus enteritis
WANG Yu;QIN Jun;XIONG Zhi-ying;HU Xiang-yun
Objective To explore the effect and mechanism of Live Combined Bacillus Subtilis and Enterococcus Faecium Granules with Multivitamines(Medilac-Vita)on mannan-binding protein level of the infants with rotavirus enteritis.Methods Forty infants with ratavirus enteritis admitted by our hospital from August 2014 to March 2016 were selected as the study subjects.They were randomly divided into two groups,each with 20 cases.The children in the control group were given only routine treatment,the children of the observation group were treated with Medilac-Vita and routine treatment,and the 20 infants who underwent health examination in the hospital were selected as healthy group at the same time.Changes in MBP levels were compared before and after the treatment of three groups.Results Before treatment,the MBP of the observation group and the control group were compared with the healthy group,and the differences were statistically significant(P＜0.01).After treatment,the MBP of the observation group was compared with the control group,and the differences were statistically significant(P＜0.01).The MBP was compared before and after treatment in the observation group and control group,and the differences were statistically significant(P＜0.01).The MBP was compared before and after treatment in the healthy group,and the difference was not statistically significant(P＞0.05).Conclusion Raravirus enteritis can cause the decline of MBP level in sera.With the cure of raravirus enteritis,MBP increases gradually.Medilac-Vita has no direct effect on MBP,however Medilac-Vita has obvious curative effect on the treatment of raravirus enteritis and can strengthen immune system of infants with raravirus enteritis,which is worthy of being applied in clinical practice.
2017 Vol. 24 (28): 117-119 [
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Feasibility study of vaginal delivery after cesarean section in re-pregnant women
HU Min-hua;LIANG Mei-fen
Objective To explore the feasibility of vaginal delivery after cesarean section in re-pregnant women.Methods Altogether 172 cases of re-pregnant women after cesarean section in our hospital from January 2015 to December 2016 were selected as subjects and divided into two groups according to the wishes of pregnant women and their families,with 86 cases in each group.Among them,experiment group adopted vaginal delivery,while control group continued to adopt cesarean delivery.The maternal and fetal indicators of the two groups were observed and comparatively analyzed.Results The duration of labor and hospitalization time of pregnant women in experiment group were significantly shorter than those of control group,the amount of bleeding of experiment group was significantly less than that of control group,the postoperative thrombosis rate and perinatal infection rate of experiment group were significantly lower than those of control group,the differences were statistically significant(P＜0.05).The neonatal weight and Apgar score of experiment group were compared with control group,and the differences were not statistically significant(P＞0.05).The adverse results of the neonates in experiment group were compared with control group,and the differences were not statistically significant(P＞0.05).Conclusion Selection of vaginal delivery for pregnant women after cesarean section can significantly shorten the duration of labor,reduce trauma,the amount of bleeding and the infection rate.It′s safe,realible and reduce the cost of delivery.Therefore,in the premise of strictly surgical indications,pregnant women are encouraged to accept vaginal delivery.
2017 Vol. 24 (28): 120-122 [
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Clinical effect of different doses of Budesonide Suspension in the treatment of acute asthma in children
LI Qing
Objective To analyze the clinical effect of different doses of Budesonide Suspension in the treatment of children with acute asthma attack.Methods A total of 86 children admitted to our hospital from June 2015 to August 2016 were selected as subjects for the study.All the children were randomly divided into the study group and the control group,43 cases in each group.The children in control group were given inhalation of low doses of Nebulized Budesonide.The children in study group were given large doses of Nebulized Budesonide treatment,and on those basis,the children of two groups were given atomization inhalation of Terbutaline Sulfate Solution.The clinical efficacy and clinical symptoms of the two groups were observed and compared.Results In the study group,19 cases were significant effective,22 cases were effective,2 cases ineffective,the total efficiency (95.35%)was significantly higher than that in the control group(72.1%),the difference was statistically significant(P＜0.05).The clinical symptoms disappear time of cough,wheezing,breathing difficulty and wheezing sound of children in the study group were significantly shorter than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion High dose of 1 mg of Budesonide in the treatment of children with acute asthma has significant curative effect,worthy of clinical popularization.
2017 Vol. 24 (28): 123-125 [
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141
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Effect of Carboprost Tromethamine combined with cervical clamp for treatment of postpartum hemorrhage caused by uterine inertia
GUO Yan
Objective To investigate the effect of Carboprost Tromethamine (Hemabate)combined with cervical clamp for treatment of postpartum hemorrhage caused by uterine inertia.Methods 80 cases with postpartum hemorrhage caused by uterine inertia of spontaneous vaginal delivery from January 2015 to January 2017 in our hospital were selected as research objects,and they were randomly divided into two groups,each 40 cases.The patients in control group was treated with simple cervical jaws,the patients in observation group was treated with Hemabate deep intramuscular injection in the base of the control group.Then the blood loss after 2 hours and 24 hours,hemostasis time,coagulation function,complications and conditions of prognosis were compared between the two groups.Results The blood loss after 2 hours and 24 hours of patients in observation group were respectively [(506.5±31.8)ml]and [(565.5±35.1)ml],they were significantly less than[(658.9±45.9)ml,(789.6±58.5)ml]of patients in the control group,the differences were statistically significant(P＜0.05).The hemostasis time of patients in observation group [(55.8±9.9)min]was shorter than that in the control group[(125.2±18.5)min],the difference was statistically significant(P＜0.05).After the intervention,the blood coagulation function index of the patients in the observation group,such like PT [(13.5±1.1)s],TT [(11.5±2.4)s],APTT[(21.6±1.3)s]were lower than those in the control group[(33.6±2.1)s，(21.5±2.5)s，(41.7±3.4)s],while Fib[(1.7±0.3)g/L]was higher than that in the control group[(0.8±0.1)g/L],the differences were statistically significant(P＜0.05).The incidence of bladder injury(2.5%),cervical necrosis(2.5%)and hemorrhagic shock(2.5%)of patients in observation group were significantly lower than those in the control group(7.5%,7.5%,12.5%),the differences were statistically significant(P＜0.05).The need for hysterectomy ratio of observation group(2.5%)was significantly lower than that in the control group(27.5%),and the difference was statistically significant(P＜0.05).Conclusion The treatment of postpartum hemorrhage caused by uterine inertia by using Carboprost Tromethamine combined with cervical clamp is ideal for the clinical hemostasis effect,with few complications,and it is worth promoting the application.
2017 Vol. 24 (28): 126-128 [
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Application observation of delivery in liberal position at the first-stage labor
QIAN Ling;LI Lan;LIAN Jie-jia;JIANG Hai-tao
Objective To observe the clinical application effect of delivery in liberal position at the first-stage labor.Methods From January 2014 to September 2016,112 puerperae for delivery admitted into our hospital were selected as research objects.By a random number method,they were evenly divided into two groups.In observation group,labor in liberal position like squatting,lying,sitting,kneeling,standing,and walking was available for puerperae at the first-stage labor.In control group,regular position for delivery was adopted.The clinical effect in the two groups was compared.Results In the observation group,there were 50 puerperae in spontaneous labor,4 in cesarean section and 2 in vaginal assistant labor,the proportion of spontaneous delivery in observation group (87.50%)was significantly higher than that in control group(73.21%),the difference was statistically significant(P＜0.05).The time of first-stage labor and total labor stage of puerperae in the observation group were much shorter than those in the control group,the differences were statistically significant(P＜0.05).The incidence of lateral episiotomy,perineal laceration and fetal asphyxia of puerperae in observation group were lower than those in control group,the differences were statistically significant(P＜0.05).The incidence of postpartum hemorrhage and neonatal mortality compared with the two groups,the differences were not statistically significant(P＞0.05).Conclusion Selection of liberal position at the first-stage labor can increase maternal comfort,mobilize their subjective initiative,promote spontaneous labor,reduce the incidence of cesarean section and complications,which is beneficial to safeguard maternal and child health.
2017 Vol. 24 (28): 129-131 [
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Clinical observation of Resuqing Granules for children combined with Ribavirin in the treatment of hand-foot-mouth diseases
ZHENG Gen-lin;LYU Shu-hua;KANG Feng
Objective To explore the clinical effect of Resuqing Granules for children combined with Ribavirin in the treatment of hand-foot-mouth diseases.Methods 80 children with hand-foot-mouth diseases treated in our hospital from November 2015 to November 2016 were selected as subjects.By a random number table,they were evenly divided into observation group and control group,40 cases in each group.The children in the control group were treated with Ribavirin,and the children in the observation group were treated with Resuqing Granule on the base of Ribavirin.The related indicators including the disappearing time of rash,fever-abating time and therapeutic effect of the two groups were observed and compared.Results In the observation group,the disappearing time of rash,fever-abating time and healing time were respectively[(3.78±1.61)d,(2.42±0.32)d,(5.28±1.37)d],which were much better than those in the control group[(6.15±1.53)d,(4.63±1.12)d,(7.43±1.13)d],and the differences were statistically significant(P＜0.05).The total effective rate in the observation group(95%)was higher than that in the control group(77.5%),and the difference was statistically significant(P＜0.05).Conclusion On the basis of Ribavirin,Resuqing Granule in the treatment of hand-footmouth diseases can shorten the time of abating fever,improve clinical symptoms,shorten the course of disease in high efficacy and safety,which is worthy of promotion and application.
2017 Vol. 24 (28): 132-134 [
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The value of conventional two-dimensional ultrasound combined with ultrasonic elastography in the diagnosis of axillary lymph nodes in breast cancer
YU Jin-tao;LI Min-er
Objective To investigate the value of two-dimensional ultrasound combined with ultrasonic elastography in the diagnosis of axillary lymph nodes in breast cancer.Methods A totalof 60 cases of breast cancer patients in our hospital from March 2014 to December 2016 were selected as research objects.78 identical axillary axillary lymph nodes were examined by conventional two-dimensional ultrasound (C2D-US),ultrasonic elastography (UE)and joint inspection,the results of pathological biopsy guided by ultrasound wereregardas the gold standard,the diagnostic results of C2D-US,UE and the joint inspection,were compared.Results Pathological biopsy revealed 35 benign lymph nodes and 43 malignant lymph nodes.The sensitivity of C2D-US,UE and C2D-US combined with UE was 74.29%,80.00%and 94.29%,respectively.The specificity was 79.07%,81.39%and 93.02%,respectively.The accuracy was 76.92%,80.77%and 93.59%,respectively.The sensitivity,specificity and accuracy of C2D-US combined with UE in the diagnosis of axillary lymph nodes in breast cancer was significantly higher than that of using single C2D-US or UE diagnosis,the difference was statistically significant(P＜0.05).Conclusion The use of conventional two-dimensional ultrasound combined with ultrasonic elastography in the diagnosis of axillary lymph nodes in breast cancer can improve the diagnostic efficacy of axillary lymph nodes,and is worthy of clinical promotion.
2017 Vol. 24 (28): 135-137 [
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146
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CT image analysis for patients with nodular goiter
YING Jie
Objective To explore the characteristics of CT images of nodular goiter in order to provide guidance and basis for correct clinical diagnosis.Methods From February 2014 to February 2017,63 patients with nodular goiter confirmed by surgical pathology were selected.CT images on these participants were retrospectively analyzed.Results CT scan images were all displayed with thyroid enlargement accompanied by low density round or quasi-circular shadow.The images were mostly presented with uneven enhancement by enhancement scan.Of the 63 patients,calcification in lesions was 31(49.21%),and clear margin was 52(82.54%).There was 47(74.60%)nodules in diffuse distribution and 16 cases in restricted distribution.For the former,31 cases were with unilateral lesions and 16 ones were in bilateral.For the latter,5 cases were with single nodules and 11 ones were presented with multiple nodules.Among all selected images,21 cases were accompanied with cystic degeneration (33.33%),10 ones with tracheal deformation due to compression (15.87%),5 with lesions into the sternum (7.93%),and 8 with enlarged cervical lymph nodes(12.70%).Homogeneous enhancement was visible by enhancement scan.Conclusion CT scan especially enhancement scan can clearly show whether the edge of the lesion is regular,calcified form,and enhanced features with a high accuracy for the diagnosis of nodular goiter.In addition,it can evaluate the relationship between the lesion and its surrounding structure and has an important value in the diagnosis and identification of patients with nodular goiter.
2017 Vol. 24 (28): 138-140 [
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Observation of the effect of Amiodarone combined with Wenxin Granule in the treatment of coronary heart disease complicated with arrhythmia in elderly patients
JIANG Xiao-jie;LIU Fang-peng;TU Zhe-hong;LI Shun-hui
Objective To observe the effect of Amiodarone and Wenxin Granule in the treatment of coronary heart disease and arrhythmia in elderly patients.Methods 85 cases of elderly patients with coronary heart disease and arrhythmia who were admitted to the outpatient in our hospital from June 2014 to July 2016 were selected as the study subjects.According to the random arrangement table method,the patients were divided into control group and observation group.42 patients in the control group were given Amiodarone for treatment,and 43 patients in the observation group was given Wenxin Granules+Amiodarone for treatment.Before and after treatment,the improvement of angina and arrhythmia(ventricular number，short array of ventricular speed)was observed before and after the treatment.The changes of hemodynamic indexes were measured in both groups，and the records of adverse events during treatment was compared.Results At the time of admission，the number of angina pectoris,times,the number of premature ventricular contraction,and the number of short array of ventricular fibrillation,there were no significant difference compared with the control group (P＞0.05).After treatment，the indexes in the observation group respectively，the curative effect of arrhythmia and angina pectoris was better than that in the control group,with significant difference (P＜0.05);upon admission，the hemodynamic index of plasma specific viscosity in the observation group,low shear viscosity,high shear viscosity fibrinogen,hematocrit were no significant differences compared with those in the control group,with significant difference (P＞0.05).After treatment，the improvement of hemodynamic indexes in the observation group were all better than those in the control group,with significant difference (P＜0.05);the incidence rate in the observation group was 9.3%,compared with 14.3%in the control group,there was no significant difference between the two groups (χ2=1.201,P＞0.05).Conclusion After the combined treatment of amiodarone and wenxin granule for elderly patients with coronary heart disease and arrhythmia，the arrhythmia is improved,hemodynamics is recovered,and the adverse reactions are less.
2017 Vol. 24 (28): 141-143 [
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Effect of different dosage hormone combined with Cyclophosphamide and Tripterygium Wilfordii in the treatment of nephrotic syndrome in middle and old aged patients
HU Chun-an;GAN Niu-qin
Objective To explore the clinical effect of different dosage hormone combined with Cyclophosphamide and Tripterygium Wilfordii in the treatment of nephrotic syndrome in middle and old aged patients.Methods 100 middle and old aged patients with nephrotic syndrome in our hospital from March 2014 to February 2016 were selected.Patientsweredividedinto Ⅰ,Ⅱ,Ⅲ and Ⅳgroups,andeach group was 25 cases.On the basis of Cyclophosphamide and Tripterygium Wilfordii,patients in different groups were treated with different doses of prednisone acetate.The dosage and medication of prednisone acetate for four groups of patients were as follows： group Ⅰ[0.4 mg/(kg·d)];group Ⅱ[0.6 mg/(kg·d)];group Ⅲ[0.8 mg/(kg·d)];group Ⅳ[1.0 mg/(kg·d)],and were taken in every morning.3 months later,the treatment effect among four groups were compared.Results After 3 months of continuous treatment,the effective rate of clinical treatment in groupⅣwas 100%,significantly higher than 92%in the other three groups,and in the improvement of urine protein content,plasma albumin level,blood creatinine and other indicators,it was also significantly better than the other three groups,and the difference was significant(P＜0.05).Conclusion Cyclophosphamide combined with Tripterygium Wilfordii and prednisone acetate in the treatment of nephrotic syndrome in middle-aged and elderly patients can achieve better results,especially when the dose hormone drug prednisone acetate is 1.0 mg/(kg·d),the treatment is best.Therefore,it has good clinical application and promotion value.
2017 Vol. 24 (28): 144-146 [
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Clinical effect of dexamethasone on chemotherapy in patients with advanced non-small cell lung cancer
HUANG Zuo-chao;LIU Yi;ZENG Chun-sheng;KANG Zhao-xun;LI Zhao-yan;WANG Ju-ping
Objective To investigate the clinical effect of dexamethasone on chemotherapy in patients with advanced non-small cell lung cancer(NSCLC).Methods Eighty patients with advanced NSCLC admitted into our hospital from January to December in 2016 were enrolled and randomly divided into two groups.40 cases of the control group was used with chemothrapy,while 40 cases of the research group was added with dexamethasone.The therapeutic effect was compared in both groups.Results There was no statistically significant difference in short-term effective rate between the two groups(P＞0.05).Before therapy,the levels of HIF-1α and VEGF had no statistically significant difference (P＞0.05).After treatment,they were both improved,and the levels in the research group were much lower compared with those in the control group (P＜0.05).Before treatment,the immune function in the two groups had no statistically significant difference(P＞0.05).After treatment,they were both improved,and improvement in the research group was superior to that in the control group (P＜0.05).Conclusion For patients with advanced NSCLC,combination of dexamethasone is beneficial to improve patients′immune function,which should be recommended for clinical application.
2017 Vol. 24 (28): 147-149 [
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Clinical effect of acupuncture combined with bloodletting on cervical spondylosis of vertebral artery type
CAO Jun-yong;WEI Li-li
Objective To investigate the clinical effect of acupuncture combined with bloodletting in the treatment of cervical spondylosis of vertebral artery type.Methods From December 2015 to December 2016,90 patients with vertebral artery cervical spondylosis treated in our hospital were selected.According to the order of treatment,theywere randomly divided into research group (acupuncture plus bloodletting on Dazhui(DU 14)and control group(acupuncture alone).The therapeutic effect,and score of symptoms and function before and after treatment were compared between the two groups.Results The total effective rate was 95.6%and 80.0%in the research group and control group respectively with a statistical difference (P＜0.05).Before treatment,there was no great difference in the score of the symptoms and function between the two groups(P＞0.05).After therapy,the score of the symptoms and function in the two groups were statistically significant,and the differences in the research group were superior to those in the control group (P＜0.05).The improvement indexes of the symptoms and function in the two groups were also displayed statistical significance,and the differences in the research group were better(P＜0.05).Conclusion Acupuncture combined with bloodletting can obtain a ideal effect in the treatment of cervical spondylosisof vertebral artery type.
2017 Vol. 24 (28): 150-152 [
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160
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Clinical effect of modified Unicorn-Rearing Pills in the treatment of infertility women with thin endometrium
LU Jun;HE Yu-ting;ZHONG Su-qin
Objective To observe the clinical effect of modified Unicorn-Rearing Pills in the treatment of infertility women with thin endometrium.Methods Altogether 44 cases of infertility women with thin endometrium treated in our hospital from January 2015 to January 2017 were randomly selected and divided according to the treatment method into two groups,and there were 22 cases in each group.The control group was treated with conventional Estradiol Valerate Tablets,while the treatment group was given oral administration of traditional Chinese medicine modified Unicorn-Rearing Pills.The endometrial thickness,endometrial blood flow resistance (RI),total effective rate,pregnancy rate and abortion rate were observed before and after treatment in the two groups.Results The total effective rate of the treatment group was significantly higher than that of the control group (P＜0.05),the pregnancy rate was higher than that of the control group,the rate of abortion was significantly lower than that of the control group(P＜0.05).The endometrial thickness and RI in the treatment group were significantly better than those in the control group (P＜0.05).Conclusion The effect of modified Unicorn-Rearing Pills of traditional Chinese medicine in the treatment of infertility women with thin endometrium is exact,and can improve clinical symptoms of patients can improve the clinical symptoms of patients,increase endometrial thickness,improve endometrial blood circulation,improve pregnancy rates and reduce the rate of miscarriage and is worthy of promotion.
2017 Vol. 24 (28): 153-155 [
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Effect analysis of traditional Chinese medicine rehabilitation training method in the adjuvant treatment of osteoporotic thoracolumbar vertebral compression fracture in elderly patients
WAN Chang-hao;WAN Zhong
Objective To investigate the clinical effects of traditional Chinese medicine rehabilitation training in the adjuvant treatment of osteoporotic thoracolumbar vertebral compression fracture in elderly patients.Methods 90 patients with aged osteoporotic thoracolumbar vertebral compression fracture in our hospital from March 2015 to August 2016 were selected as research objects.According to the method of random number table,those patients were divided into the control group and the observation group,45 cases in each group.The control group was treated with simple western medicine,while the observation group was given traditional Chinese medicine rehabilitation training combine with western medicine.After 1 months of treatment,the curative effect was compared and the pain status and life function score of the two groups were observed.Results The average angle of Cobb,the average score of pain status and the average score of life function of the observation group after 1 months treatment was significantly better than that of the control group,with significant difference (P＜0.05).The total effective rate after treatment in the observation group was 95.56%,which was significantly higher than 71.11%in the control group,with significant difference (P＜0.05).Conclusion Traditional Chinese medicine rehabilitation training is effective on patients with aged osteoporotic thoracolumbar vertebral compression fracture,and it is worthy of clinical application and promotion.
2017 Vol. 24 (28): 156-158 [
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Application of human chorionic gonadotropin review table in the followup of hydatidiform mole in cancer clinic
WEI Wan-xia;LI Jun-fang;YANG Shu-ling
Objective To investigate the application of human chorionic gonadotropin(HCG)review table in the followup of hydatidiform mole in cancer clinic.Methods From December 2014 to May 2017,98 patients who were followed up at the cancer clinic after the removal of the hydatidiform mole in our hospital were selected and divided into the control group(n=49)and the experimental group(n=49)according to the random number table method.The patients in the control group were given health education,and instructed them to follow up in the outpatient department.The patients in the experimental group were followed up for HCG review.The follow-up and patient satisfaction were compared between the two groups.Results The proportion of accurate,complete the results of HCG reexamination,follow-up visits,complete follow-up planner in the experimental group was significantly higher than that of the control group,with significant difference (P＜0.05).The total satisfaction rate of the experimental group was 95.92%,which was significantly higher than 77.55%of the control group,with significant difference (P＜0.05).Conclusion The application of HCG in the follow-up of tumor patients is of great significance to improve the quality of referral and the rate of referral and improve patient satisfaction.It is worthy of clinical reference and comprehensive use.
2017 Vol. 24 (28): 159-161 [
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Investigation and intervention countermeasures in disposal of blood splashes of township hospital delivery room
TANG Jian-hua;XIAO Li-Bing;LIU Yan
Objective To grasp the disposal methods of blood splashes of 21 township hospitals in the delivery room with in jurisdiction,and to implement prevention and control measures of nosocomial infection.Methods 63 nurses from 21 township hospitals within the jurisdiction from April 2016 to May 2017 were selected as the subjects,the management of disinfectant and the management knowledge of the village nurses were investigated and intervened,the result before and after intervention was compared.Results The correct rate of delivery room related knowledge answer,the qualified rate of concentration selection and preparation of disinfectant with chlorine,the qualified rate in blood splashes of cleaning and disinfection operation examination and six step washing manipulation assessment after intervention was higher than that before intervention,with significant difference (P＜0.01).Conclusion There are many defects in the environment cleaning and disinfection management in delivery room of 21 township hospitals in the jurisdiction,and the related knowledge of nursing staff is not enough.Strengthening the training and supervision of related knowledge,improving the awareness rate of related personnel,and grasping the weak link of delivery room in township hospitals are the keys to implement the prevention and control measures of nosocomial infection.
2017 Vol. 24 (28): 162-166 [
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Observation of preventive effect of acupuncture point moxibustion with Tradeitional Chinese Medical nursing intervention to prevent the deep venous thrombosis after total knee replacement
MA Guo-hua
Objective To investigate the effect of Traditional Chinese Medicine acupuncture point moxibustion with tradeitional Chinese medical nursing interventin to prevent the deep venous thrombosis(DVT)after total knee replacement(TKA).Methods The 60 patients admitted to our hospital from May 2010 to May 2017 were selected as the subjects of the study,and they were divided into two groups according to the order of admission,each with 30 cases.The control group underwent interventions including limb lift,ankle passive activity,continuous passive motion exercise and sole vein pump.The experimental group underwent interventions including limb lift,ankle passive activity,continuous passive motion exercise,sole vein pump massages on calf,biceps and quadriceps,acupuncture point moxibustion,Traditional Chinese Medicine external treatment,herbal oral and Traditional Chinese Medicine diet.The incidence of both groups was compared.Results 1 case of DVT (3.33%)was produced of postoperative in the experimental group,5 patients(16.67%)were produced in the control group,and the difference was statistically significant(P＜0.05).Conclusions The Traditional Chinese Medicine acupuncture point moxibustion with traditional Chinese medical nursing interventins help to reduce the incidence of DVT after TKA.
2017 Vol. 24 (28): 167-170 [
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Clinical effect of comprehensive nursing intervention in mini titanium plate fixation for jaw fracture
WANG Zhi-fang;LIAO Sheng-ying;GUAN Xin-yu
Objective To explore the clinical effect of comprehensive nursing intervention in mini titanium plate fixation for jaw fracture.Methods 91 patients with mini plate rigid internal fixation for jaw fracture from February 2015 to July 2016 treated in our hospital were selected as objects and were divided into two groups by nursing mode.45 patients in the control group were received routine care,and 46 patients in the observation group were given comprehensive nursing intervention.The nursing effect in two groups were compared.Results The operation time and hospitalization time of the patients in the observation group were shorter than that in the control group,while the hospitalization expenses was less than that in the control group,and the differences were statistically significant(P＜0.05).The analgesic use rate in the observation group was lower than that in the control group,while the fracture anatomical reduction rate and nursing satisfaction were higher than that in the control group,and the differences were statistically significant(P＜0.05).Conclusion The clinical effect of comprehensive nursing intervention in the treatment of jaw fracture with mini titanium plate fixation is significant and worthy of clinical promotion.
2017 Vol. 24 (28): 171-173 [
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Effect study of maternal infant bedside nursing program on primipara
GONG Chun-hong;CHEN Qiu-hua;LIU Fen
Objective To summarize and analyze the influence of maternal infant bedside nursing program on primipara.Methods 100 primipara from January to December 2016 of our hospital were selected.All patients were primipara and underwent caesarean section.Patients were randomly divided into control group and observation group.Patients in control group were given general nursing,and patients in observation group were given maternal infant bedside nursing program.The satisfaction degree of the two groups of women on the nursing program was compared,and the changes of emotional state and degree of pain before and after nursing of the two groups were compared.The degree of mastery the related contents between the two groups was compared.Results The observation group master related knowledge level was significantly higher than the control group,the difference was statistically significant;the nursing satisfaction rate in observation group was significantly higher than that of control group,the difference was statistically significant;after nursing,anxiety,depression and pain score in observation group was significantly lower than the control group,the difference was statistically significant(P＜0.05).Conclusion Mother infant bedside nursing mode is worth of widely used in clinic,which not only conducive maternal to master related knowledge,but also can stabilize the maternal mood,reduce maternal pain,improve the satisfaction degree of maternal care,and the nursing effect is very significant.
2017 Vol. 24 (28): 174-176 [
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Analysis of effect of high-quality care in prevention of phlebitis caused by intravenous infusion
LIU Mei-qing
Objective To analyze the effect of high-quality nursing in prevention of phlebitis caused by intravenous infusion.Methods Altogether 90 cases of patients with intravenous infusion who were treated in our hospital from October 2016 to March 2017 were selected and randomly divided into two groups:45 cases of the control group were given routine nursing care and 45 cases of the observation group were given the implementation of high-quality nursing.The post-treatment intravenous prevention knowledge scores,the incidence of phlebitis and the nursing satisfaction scores were compared between the two groups.Results Post-nursing treatment environment score [(8.98±1.23)points],nursing skill score[(9.32±1.25)points],health education score[(9.66±1.25)points],service attitude score[(8.97±1.65)points],nursing effect score[(9.55±1.46)points]and intravenous prevention knowledge score[(26.98±2.36)points]of patients in the observation group were higher than those in control group [(5.36±1.23),(6.68±1.45),(7.23±1.45),(6.98±1.45),(7.23±1.14),(18.32±1.25)points];the incidence rate of phlebitis(2.22%)of the observation group was significantly lower than that of control group (20.00%),with statistically significant differences (P＜0.05).Conclusion The implementation of high-quality nursing care of patients with intravenous infusion can effectively reduce the incidence of phlebitis and improve the patients′satisfaction of nursing work,which is worthy of further clinical application.
2017 Vol. 24 (28): 177-179 [
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Nursing intervention of postoperative mental disorder in patients with thoracic tumor
ZHANG Xia
Objective To investigate the method of targeted nursing for patients with chest tumor after the prevention of postoperative mental disorders.Methods A total of 150 patients with thoracic cancer in our department from October 2016 to April 2017 were selected,and randomly divided into two groups,the observation group (n=75)and the control group(n=75).The control group was received routine surgery care and prevention measures of department of thoracic.On the basis of the nursing care of the control group,the targeted nursing program of the patients in the observation group was given.The incidence,duration of POP and nursing satisfaction rate were recorded.Results The incidence of POP in the observation group (2.7%)was significantly lower than that in the control group (10.7%),and duration of POP patients in the observation group[(20.12±11.13)h]was significantly lower than that of the control group[(36.01±14.56)h],the differences were statistically significant(P＜0.05).The nursing satisfaction rate of the observation group (94.7%)was higher than that of the control group (84.0%),and the difference was statistically significant(P＜0.05).Conclusion Nursing measures to prevent postoperative mental disorders in patients with chest tumors can reduce the incidence of postoperative mental disorders and shorten the duration of POP,and greatly improve the satisfaction rate of patients.
2017 Vol. 24 (28): 180-182 [
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Effect of psychological nursing combined with health guidance on patients with advanced ovarian cancer chemotherapy
LAN Su-chun;XIE Li-qin;HUANG Cai-hong;ZHENG Li-cong
Objective To investigate the application and effect of psychological nursing and health guidance in patients with advanced ovarian cancer chemotherapy.Methods A total of 80 patients with advanced ovarian cancer chemotherapy treated in our hospital from March 2015 to January 2017 were selected as subjects.Patients were randomly divided into two groups,each with 40 cases.The general group was subjected to routine nursing intervention and the intervention group carried out psychological nursing and health guidance on the basis of general group.The chemotherapy effect of advanced ovarian cancer,the cognitive status of ovarian cancer disease,the compliance of chemotherapy,the satisfaction degree of nursing and the psychological status of SCL-90 in the patients before and after the intervention were compared between the two groups.Results The total effective rate of chemotherapy for ovarian cancer in the intervention group(92.50%)was higher than that in the general group(75.00%),and the difference was statistically significant(P＜0.05).In the intervention group,the knowledge cognition of ovarian disease,the compliance of chemotherapy compliance,and the nursing satisfaction score were all higher than those in the general group,and the differences were statistically significant(P＜0.05).Before the intervention,the each index scores of the SCL-90 of patients in the two groups were compared,and the differences were not statistically significant(P＞0.05).After intervention,the scores of SCL-90 in the intervention group was lower than that in the general group,and the difference was statistically significant(P＜0.05).Conclusion Psychological nursing and health guidance in the treatment of patients with advanced ovarian cancer chemotherapy is effective,they can effectively improve the negative emotions of patients,deepen their understanding of ovarian cancer disease knowledge,improve chemotherapy compliance and nursing satisfaction,improve the effect of chemotherapy.It is worth promoting the application.
2017 Vol. 24 (28): 183-185转189 [
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144
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186
Effect observation of extended nursing on patients after artificial hip replacement
TAN Juan
Objective To investigate the effect of extended nursing care on the quality of life in patients after artificial hip replacement.Methods Altogether 30 patients who underwent artificial hip replacement in our hospital from January to December 2016 were involved as observation group,while another 30 patients who underwent artificial hip replacement in our hospital from January to December 2015 were involved as control group.Control group received routine discharge guidance and the patients were followed up for 7～10 days after discharge,followed by regular outpatient followup.Observation group accepted extended nursing until 3 months after discharge.The Harris hip function scale score,Barthel index rating scale score and patient satisfaction questionnaire score at discharge,4 weeks,12 weeks after discharge and incidence of joint dislocation complications were compared between the two groups within 12 weeks after discharge.Results When discharged,the Harris hip score,Barthel index score and satisfaction degree compared between the two groups were not statistically significant(P＞0.05).In the 4 weeks and 12 weeks after discharge,the Harris hip score,Barthel index score and satisfaction of the observation group were higher than the control group,and the differences were statistically significant(P＜0.05).The incidence of joint dislocation complications in the observation group was lower than the control group within 12 weeks after discharge,and the difference was statistically significant(P＜0.05).Conclusion Extended nursing can effectively promote the improvement of the hip joint function after artificial hip replacement,improve patients′post-operative self-care ability and satisfaction and reduce the complications of joint dislocation,which promotes the body recovery and effectively improves the patient's quality of life.
2017 Vol. 24 (28): 186-189 [
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147
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190
Effect of prenatal clinic of maternity nurses on the mental state of pregnant women and the outcome of childbirth
WANG Ting
Objective To explore the effect of prenatal clinic of maternity nurses on the mental state of pregnant women and the outcome of childbirth.Methods 160 primiparous women who received delivery in our hospital from August to December 2016 were selected as subjects and were randomly divided into two groups according to the random number table method,80 cases per group.The control group was treated with traditional nursing model.The observation group received the regular prenatal clinic.The eutocia rate,cesarean section rate,2 h blood volume of postpartum,Apgar score in the first 1 min after the birth of the newborn,maternal anxiety and depression scores and indicators of neonatal after 3 months were compared between the two groups.Results The cesarean section rate of pregnant women in observation group(26.2%)was lower than that in the control group(47.5%),the 2 h blood volume of postpartum of pregnant women in observation group[(156.28±64.71)ml]was less than the control group[(192.53±56.31)ml],and the differences were statistically significant(P＜0.05).The Apgar score in the first 1 min after the birth of the newborn of the two groups were compared,and the difference was not statistically significant(P＞0.05).After delivery,the anxiety and depression scores in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).After 3 months,the weight gain of neonates in the observation group was faster than that of the control group,the respiration and pulse rate were less than the control group,and the differences were statistically significant(P＜0.05).Conclusion The prenatal clinic dominated by midwife nurses has a better effect on improving the outcome of childbirth and the mental state of pregnant women,help to reduce cesarean section rate and maternal bleeding,improve the health of newborns,which is worthy to promote in clinic care for puerpera.
2017 Vol. 24 (28): 190-193 [
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147
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194
Clinical effect of nursing intervention in the prevention of complications after the intervention therapy of intracranial aneurysm
LIU Xiao-lan
Objective To explore the clinical effect of nursing intervention in the prevention of complications after the intervention therapy of intracranial aneurysm.Methods 106 patients with intracranial aneurysm treated in our hospital from March 2013 to March 2016 were selected as subjects.All patients were treated with interventional surgery and were randomly divided into two groups according to the random number table method,53 cases in each group.The conventional group adopted the conventional nursing care,the intervention group adopted the nursing intervention.The psychological state,quality of life,nursing satisfaction and complications for two groups were compared.Results Before intervention,the the SAS,SDS and ADL scores between two groups were compared,and the difference was not statistically significant(P＞0.05).After intervention,the SAS and SDS scores of intervention group were lower than those in the conventional group,the ADL scores were higher than that in the conventional group,and the differences were statistically significant(P＜0.05).The nursing satisfaction of intervention group (94.34%)were higher than that in the conventional group (79.25%),and the differences were statistically significant(P＜0.05).The incidence of complications in the intervention group(5.66%)was significantly lower than that in the conventional group(22.64%),and the difference was statistically significant(P＜0.05).Conclusion After the intervention therapy of intracranial aneurysm,the nursing intervention can promote the patient′s fast recovery,improve their psychological state and quality of life,reduce the incidence rate of complications and enhance the patient′s clinical satisfaction.It is worthy of clinical application and promotion.
2017 Vol. 24 (28): 194-196 [
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