重复经颅磁刺激结合认知训练治疗血管性认知障碍的临床疗效观察

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Abstract

Objective To observe the clinical effect of rTMS combined with cognitive training in the treatment of VCI.Methods A total of 91 patients with VCI who received rehabilitation treatment in our hospital from July 2015 to June 2016 were enrolled.The treatment group was treated with rTMS combined with cognitive training.The control group was given only cognitive training.Application of MoCA and LOTCA in patient`s cognitive assessment.Results After treatment,the MoCA total scores and individual items(execution,abstract,memory and orientation)of the treatment group were higher than those in the control group,the differences were statistically significant(P＜0.05).The total score of LOTCA and the individual items(orientation,perception,thinking)in the treatment group were higher than those in the control group,the differences were statistically significant(P＜0.05).After treatment scores of MoCA and LOTCA scales were both increased in the two groups compared with before treatment,the differences were statistically significant(P＜0.01);After treatment,in the LOTCA individual,the scores of perception,thinking and visual and spatial perception in the control group were higher than before treatment,the differences were statistically significant(P＜0.01);in the MoCA single item,the scores of other items expectnaming in the control group were higher than those before the treatment,and the differences were statistically significant(P＜0.01);the individual itemes scores of the treatment group after treatment were higher than those before treatment,the differences were stastistically significant(P＜0.01).Conclusion rTMS combined with cognitive training can improve cognitive function and the quality of life of patients with VCI.

Key words： Repetitive transcranial magnetic stimulation(rTMS) Cognitive training Vascular cognitive impairment Cognitive function

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	Articles by authors
	XU Jing-jing
	CAO Zhong-yao
	ZHANG Qing-hua

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XU Jing-jing,CAO Zhong-yao,ZHANG Qing-hua. Clinical curative effect observation of rTMS combined with cognitive training in the treatment of vascular cognitive impairment[J]. 中国当代医药, 2017, 24(28): 51-54.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I28/51

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