C反应蛋白预测远端输尿管结石自排的应用价值

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Abstract Objective To evaluate the application value of the C-reactive protein(CRP)level in predicting spontaneous stone passage in patients with 5 to 9 mm distal ureteral stones.Methods Clinical data of patients with distal ureteral stones who met the inclusion criteria from December 2014 to December 2015 were collected.CRP levels were measured.After 5 weeks,according to whether the spontaneous stone passage,the patients were divided into the stone discharging group and the stone undischarged group.The receiver operating characteristic(ROC)curve was drawn to determine the optimal cut-off values of CRP for predicting spontaneous stone passage.Results A total of 348 patients completed the study.Spontaneous stone passage was observed in 224 patients,the stone discharging rate was 53.8%.ROC analysis resulted in an area under the curve of 0.882 for serum CRP.Using ROC,a cut-off point of 8.5 mg/L for CRP yieldedappearedoptimalforpredictionofspontaneousuretericstoneexpulsion(sensitivitywas76.6%,specificitywas 86.2%).In the proportion of CRP＞8.5 mg/L,the stone undischarged group was significantly higher than that the stone discharging group,with significant statistical difference(P＜0.05).In the stone discharging group,time to spontaneous stone passage in patients with a CRP level less than or equal to 8.5 mg/L was shorter than that the CRP Level over 8.5 mg/L,the number of episodes of pain and the visual analogue scale(VAS)score were significantly less than that with a CRP level over 8.5 mg/L(P＜0.05).Conclusion CRP levels is useful for predicting.When CRP levels are greater than 8.5 mg/L,move aggressive interventions techniques should be considered.

Key words： C-reactive protein Distal ureteral stones Spontaneous stone passage Prediction

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	LI Fei-yang
	LV Jian-lin

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LI Fei-yang,LV Jian-lin. Application value of C-reactive protein level in predicting spontaneous stone passage in patients with distal ureteral stones[J]. 中国当代医药, 2017, 24(28): 79-82.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I28/79

[1]	那彦群.中国泌尿外科疾病诊断治疗指南[M].北京：人民卫生出版社，2013.
[2]	Turk C，Petrik A，Sarica K，et al.EAU guidelines on sis and conservative management of urolithiasis[J].Eur Urol，2016，69（3）：468-474.
[3]	Pickard R，Starr K，Maclennan G，et al.Medical expulsive therapy in adults with ureteric colic：a multicentre，randomised，placebo-controlled trial[J].Lancet，2015，386（9991）：341-349.
[4]	Boonla C，Tosukhowong P，Spittau B，et al.Inflammatory and fibrotic proteins proteomically identified as key protein constituents in urine and stone matrix of patients with kidney calculi[J].Clin Chim Acta，2014，429：81-89.
[5]	赵晓峰，杨树立，路彦伟，等.输尿管镜钬激光碎石治疗体外冲击波碎石失败输尿管结石临床分析[J].中国当代医药，2013，20（5）：174-175.
[6]	Clyne B，Olshaker JS.The C-reactive protein[J].J Emerg Med，1999，17（6）：1019-1025.
[7]	Ho KM，Lipman J.An update on C-reactive protein for intensivists[J].Anaesth Intensive Care，2009，37（2）：234-241.
[8]	Radovic VV.Predictive value of inflammation and myocardial necrosis markers in acute coronary syndrome[J].Med Pregl，2010，63（9-10）：662-667.
[9]	Panichi V，Migliori M，De Pietro S，et al.The link of biocompatibility to cytokine production[J].Kidney Int Suppl，2000，76：S96-S103.
[10]	梁展华.超敏C-反应蛋白在肝病诊断中的应用价值[J].中国当代医药，2010，17（18）：74-75.
[11]	Paajanen H，Tainio H，Laato M.A chance of misdiagnosis between acute appendicitis and renal colic[J].Scand J Urol Nephrol，1996，30（5）：363-366.
[12]	Sandberg T，Lidin-Janson G，Eden CS.Host response in women with symptomatic urinary tract infection[J].Scand J Infect Dis，1989，21（1）：67-73.
[13]	Yilmaz E，Batislam E，Tuglu D，et al.C-reactive protein in early detection of bacteriemia and bacteriuria after extracorporeal shock wave lithotripsy[J].Eur Urol，2003，43（3）：270-274.
[14]	Pulliam PN，Attia MW，Cronan KM.C-reactive protein in febrile children 1 to 36 months of age with clinically undetectable serious bacterial infection[J].Pediatrics，2001，108（6）：1275-1279.
[15]	Shaoul R，Lahad A，Tamir A，et al.C reactive protein （CRP）asapredictorfortruebacteremiainchildren[J].MedSciMonit，2008，14（5）：R255-R261.
[16]	Bleeker SE，Derksen-Lubsen G，Grobbee DE，et al.Validating and updating a prediction rule for serious bacterial infection in patients with fever without source[J].Acta Paediatr，2007，96（1）：100-104.
[17]	Angulo JC，Gaspar MJ，Rodriguez N，et al.The value of C-reactive protein determination in patients with renal colic to decide urgent urinary diversion[J].Urology，2010，76（2）：301-306.
[18]	Sfoungaristos S，Kavouras A，Katafigiotis I，et al.Role of white blood cell and neutrophil counts in predicting spontaneous stone passage in patients with renal colic[J].BJU Int，2012，110（8 Pt B）：E339-E345.
[19]	Yamaguchi K，Minei S，Yamazaki T，et al.Characterization of ureteral lesions associated with impacted stones[J].Int J Urol，1999，6（6）：281-285.
[20]	Park CH，Ha JY，Park CH，et al.Relationship between spontaneous passage rates of ureteral stones less than 8 mm and serum C-reactive protein levels and neutrophil percentages[J].Korean J Urol，2013，54（9）：615-618.
[21]	Aldaqadossi HA.Stone expulsion rate of small distal ureteric calculi could be predicted with plasma C-reactive protein[J].Urolithiasis，2013，41（3）：235-239.
[22]	Ozcan C，Aydogdu O，Senocak C，et al.Predictive factors for spontaneous stone passage and the potential role of serum C-reactive protein in patients with 4 to 10 mm distal ureteral stones：a prospective clinical study[J].J Urol，2015，194（4）：1009-1013.