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2017 Vol. 24, No. 33
Published: 2017-11-28
 
 
4 Study of Curcumin on hepatic stellate cells in rats
WU Xiong-jian；ZHENG Hong；ZHU Hai-yan；MAO Zhong-yi；XIE Jun
ObjectiveTo explore the mechanism of Curcumin on the prevention and treatment of liver fibrosis in rats,so as to provide reference for clinical treatment.MethodsThe rat model of experimental liver fibrosis induced by CCl4was established.At the same time,20 mg,10 mg and 5 mg Curcumin were in lavage in every 100 g body weight,the corresponding models were set as delivery model group,model group and control group respectively,10 rats in each group.The level of reactive oxygen species(ROS)in serum was detected by colorimetric method.Malondialdehyde(MDA)content in liver tissue was detected by MDA assay kit(TBA method).By electrophoretic mobility shift assay(EMSA),the activity of NF-κB in liver tissue was detected.The levels of NF-κB expression,TGF-β1,platelet-derived growth factor-BB(PDGF-BB)and recombinant human connective tissue growth factor(CTGF)in liver tissue were detected by immunohistochemistry.The mRNA level of tissue inhibitor of metalloproteinase-1 in liver tissue was detected by RT-PCR.The results after detection were statistically analyzed.ResultsIn the model group,the levels of ROS,endotoxin,MDA,NF-κB,TGF-β1,PDGF-BB,CTGF and TIMP-1mRNA were significantly higher than those in the normal group,and the differences were statistically significant(P<0.05).The levels of above-mentioned factors in the delivery model group were all lower than those in the model group,and the differences were statistically significant(P<0.05).ConclusionCurcumin presents with the inhibition of ROS and endotoxin levels in serum,MDA,NF-κB,TGF-β1,PDGF-BB,CTGF,and TIMP-1 mRNA expression in liver tissue to some extent and participants in the liver fibrosis prevention through a variety of mechanisms.
2017 Vol. 24 (33): 4-06 [Abstract] ( 163 ) HTML (38 KB)  PDF  (0 KB)  ( 40 )
7 Influence of hyperbaric oxygen therapy on the expression of Nogo-A and NgR after traumatic brain injury in rats
TU Yao-ran ；NIU Fan； HONG De-quan ；HU Yong
ObjectiveTo investigate the influence of hyperbaric oxygen therapy on the expression of Nogo-A and NgR after traumatic brain injury in rats.MethodsOne hundred SD rats(SPF grade）were selected and established as acute moderate traumatic brain injury models using Feeney′s method.The models were randomly divided into treatment group(n=20)and injury group(n=80).In the injury group,no special treatment was applied,while in the treatment group,hyperbaric oxygen was adopted after successful modeling.The differences in the expression of Nogo-A and NgR in rats 1,3,5,7 and 10 days after the trauma of rats in two groups were observed.ResultsThe expression of Nogo-A and NgR were highest in the third day after trauma in both the treatment and injury groups.The Nogo-A and NgR expression in the treatment group were all lower than those in the injury group 1,3,5,7 and 10 days after the trauma,and the differences were statistically significant(P<0.01).ConclusionDown-regulation of Nogo-A and NgR expression by hyperbaric oxygen is one of the mechanisms of promoting central nerve regeneration.
2017 Vol. 24 (33): 7-09 [Abstract] ( 185 ) HTML (33 KB)  PDF  (0 KB)  ( 39 )
10 Effect of Alogliptin combined with Glimepiride in diabetes rats and its influence on islet β cells function
WU Jian ；WEN Jian-dong ；XIAO Lin-lin ；XUE Xiao-yan ；DUAN De-zheng
ObjectiveTo investigate the hypoglycemic effects and the function of islet β cells of Alogliptin combined with Glimepiride in type 2 diabetes mellitus rats.Methodsfifty rats of type 2 diabetes mellitus which were induced through high-sucrose and high-fat diet combined with low-dose abdominal injection of Streptozotocin were randomly divided into five groups:model group(group A),Alogliptin group(group B),Glimepiride group(group C),Alogliptin combined with Glimepiride group (group D),Alogliptin combined with Glibenclamide (group E),10 rats in each group.Another 10 normal rats were selected as normal group(group F).The fasting blood glucose(FBG),level of plasma insulin(FIns),total cholesterol(TC)and triglyceride(TG)levels were detected in rats after treated for 28 days,the HOMA-βF index and insulin resistance index(HOMA-IR)were calculated.ResultsAfter 28 d treatment,the FBG,TG,TC,Fins and HOMAIR of the rats in group A,B,C,D and E were all higher than those in group F,the HOMA-βF was lower than group F,and the differences were statistically significant(P<0.01).The FBG,TG,TC,FIns,and HOMA-IR of rats in group B,C,D and E were significantly lower than those in group A,and HOMA-βF was higher than group A,and the differences were statistically significant(P<0.01).The FBG and FIns of rats in group C were lower than those in group B,TG and TC were higher than those in group B,the differences were statistically significant(P<0.05).The FBG,TG,TC,Fins and HOMA-IR of rats in group D and E were significantly lower than those of group B,HOMA-βF was higher than group B,and the differences were statistically significant(P<0.01).The FBG,TG,TC,FIns and HOMA-IR of the rats in group D and E were lower than those in group C,HOMA-βF was higher than that in group C,and the differences were statistically significant(P<0.05).There was no statistically significant difference between D and E groups(P>0.05).ConclusionAlogliptin,Glimepiride single or combined can significantly reduce the blood glucose of type 2 diabetic rats,improve TG,TC,the function of islet β cell and insulin resistance,but combined effect is better than single drug therapy.
2017 Vol. 24 (33): 10-12 [Abstract] ( 211 ) HTML (35 KB)  PDF  (0 KB)  ( 47 )
13 Determination of Paracetamol and Chlorogenic Acid in Qiangli Ganmao Tablets by HPLC-UV
GAO Hua-rong； SUN Xiang-min
ObjectiveTo establish a method for determination of Paracetamol and Chlorogenic Acid in Qiangli Ganmao Tablets.MethodsBy high performance liquid chromatography with ultraviolet spectrometry (HPLC-UC)method,the content of Chlorogenic Acid and Paracetamol were determined.The column was Inertsil ODS-SP (5 μm,4.6×250 mm),the mobile phase was the mixture of methanol-acetonitrile (the volume ratio was 1:2)-0.1%phosphoric acid(20:80).The column temperature was 35.0℃,the flow velocity was 1.0 ml/min,the wavelength was 329 nm and 243 nm respectively.ResultsThe linear range of Paracetamol and Chlorogenic Acid were at 0.7-112 μg/ml(r=0.9999)and 0.51-102 μg/ml(r=0.9995)respectively.The content of Paracetamol and Chlorogenic Acid was 195.8 mg and 2.23 mg respectively.ConclusionThe method used for the simultaneous determination of Paracetamol and Chlorogenic Acid in Qiangli Ganmao Tablets is simple and accurate.
2017 Vol. 24 (33): 13-16 [Abstract] ( 190 ) HTML (35 KB)  PDF  (0 KB)  ( 39 )
17 Research advance of pathogenesis and clinical application of Sini Powder
YAN Bing；YANG Zhuo-xin； PI Min；CHEN Peng-dian；ZENG Ping-ping；LIN Hui-yuan
As a prescription for coordinating shaoyang,Sini Powder has the effect of soothing the liver and regulating the spleen,clearing away pathogenic factors and relieving depression,and has a better effect on treating the disease of liver stagnation and spleen deficiency type.Based on the original Sini Powder formula,this paper analyzes the pathogenesis of major therapeutic diseases for Sini Powder combining with the description for the major therapeutic diseases for Sini Powder of physicians of past dynasties,and concludes that its primary pathogenesis is obstruction of pathogen and stagnation of yangqi due to qi stagnancy of both liver and spleen.While simultaneously,it discovers the value of soothing liver-qi stagnation and harmonizing the function of qi through the observation of widespread clinical application and good treatment effect of Sini Powder.
2017 Vol. 24 (33): 17-20 [Abstract] ( 187 ) HTML (44 KB)  PDF  (0 KB)  ( 39 )
21 Influence of DSA-guided polyol foam sclerotherapy on varicose veins of lower extremity and its influence on serum TNF-α and IL-6 levels
SONG Yu-sheng
ObjectiveTo investigate the influence of DSA-guided polyol foam sclerotherapy on varicose veins of lower extremity and its influence on serum tumor necrosis factor(TNF-α)and interleukin-6(IL-6)levels in patients with lower extremity varicose veins.MethodsAltogether 89 cases of patients with varicose vein of lower extremity who were treated in our hospital with surgeries from July 2012 to June 2016 were enrolled and randomly divided into the control group(44 cases)and the observation group(45 cases).The control group was treated with conventional stripping operation,and the observation group was treated with DSA-guided polyol foam sclerotherapy.The curative effect was compared between the two groups.ResultsThe hospitalization time,intraoperative bleeding volume,operation time and hospitalization costs of the observation group were less than those of the control group (P＜0.05).The level of TNF-α and IL-6 of the observation group at 24 h treatment were lower than those of the control group,with statistically significant difference(P＜0.05).The skin numbness and subcutaneous bleeding incidence rate of the observation group were lower than those of the control group,and the total incidence rate was also lower,with statistically significant difference(P＜0.05).The 1-year recurrence rate of the observation group was 13.33%,which was lower than 34.09%of the control group(P＜0.05).ConclusionThe DSA-guided polyol foam sclerotherapy has significant effect in the treatment of lower extremity varicose veins,with less trauma and low incidence of complications,which is worth promoting.
2017 Vol. 24 (33): 21-23 [Abstract] ( 203 ) HTML (34 KB)  PDF  (0 KB)  ( 64 )
24 Application of hydrocolloid patch and polyurethane gel pad in the prevention of facial pressure ulcer in patients with prone general anesthesia
XIE Hong-qiong ；YU Li-min ；YE Hua-li；ZHOU Xia
ObjectiveTo explore the application of hydrocolloid patch combined with polyurethane gel pad in the prevention of facial pressure ulcer in patients with prone general anesthesia.MethodsFrom April 23 in 2016 to April 23 in 2017,50 patients with prone general anesthesia in our hospital were selected and divided into the control group and the observation group according to the grouping method,25 cases in each group.The control group was given cotton pad,and the observation group was treated with hydrocolloid patch combined with polyurethane gel pad.The degree of skin damage,the incidence rate of pressure ulcers,satisfaction degree,pressure ulcer healing time,press the time of red skin completely subsided were compared between the two groups.ResultsThe incidence rate of apparent skin redness(4.00%),the incidence rate of rupture or blister(0.00%)and the incidence rate of pressure ulcer(24.00%)in the observation group were significantly lower than that in the control group (24.00%,20.00%,60.00%),the healing time of pressure ulcer and the time of red skin completely subsided in the observation group were shorter than those in the control group,the degree of satisfaction (96.00%)in the control group was higher than that in the control group (64.00%),with significant difference (P＜0.05).ConclusionFor patients with prone general anesthesia,the application of hydrocolloid patch combined with polyurethane gel pad can reduce the incidence of facial pressure ulcer.The establishment of hydrotherapy colloid paste in patients with prone to general anesthesia combined with polyurethane gel pad to prevent,can reduce the incidence of facial pressure ulcers.
2017 Vol. 24 (33): 24-26 [Abstract] ( 160 ) HTML (33 KB)  PDF  (0 KB)  ( 46 )
27 Influence of respiratory function exercise combined with family oxygen therapy on quality of life and respiratory difficulty in chronic obstructive pulmonary disease patients
LIU Wang；WU Ge-yi；LIU Tu-xuan ；HUANG Xin-wei
ObjectiveTo observe the influence of respiratory function exercise combined with home oxygen therapy on the quality of life of patients with chronic obstructive pulmonary disease (COPD)and the effect of treatment on diseases.Methods60 patients with COPD who were discharged from Respiratory Department in our hospital from March 2015 to March 2017 were selected and randomly divided into the observation group and the control group,30 cases in each group.The observation group was given respiratory function exercise combined with home oxygen therapy,while the control group was given conventional oral antiasthmatic drugs and inhaled drug control.The modified version of the St Georges respiratory questionnaire(SGRQ-C),chronic obstructive pulmonary disease assessment(CAT)score and dyspnea scale(mMRC)score were compared between the two groups after 3 months.ResultsAfter 3 months of rehabilitation treatment,the SGRQ-C score,CAT score and mMRC score of the observation group were lower than those of the control group,with significant difference(P＜0.05).ConclusionRespiratory function exercise combined with home oxygen therapy can improve the quality of life and dyspnea symptoms of patients with COPD,and improve the activity ability of patients with COPD.
2017 Vol. 24 (33): 27-29 [Abstract] ( 145 ) HTML (32 KB)  PDF  (0 KB)  ( 44 )
30 Clinical effect of T3thoracic sympathectomy under single operation port thoracoscope in the treatment of palmar hyperhidrosis
LIU Hang-hui
ObjectiveTo study the therapeutic effect of T3 thoracic sympathectomy under single operation port thoracoscope in the treatment of palmar hyperhidrosis.MethodsFrom December 2014 to December 2016,60 patients with palmar hyperhidrosis treated in our hospital were selected as the subjects of this study.According to the random number table method,all patients were divided into the single operation port group and the double operation port group,30 cases in each group.General anesthesia of Dexmedetomidine by double-lumen endotracheal intubation was provided in the two groups.The T3thoracic sympathectomy under thoracoscope was performed in both groups.The therapeutic effects which were estimated from aspects of remission of hand sweating,occurrence of profuse sweating,size of incision,operation time,bleeding,postoperative pain,hospital stay,and incidence of adverse reactions after surgery were evaluated and judged between the two groups.ResultsAll recruited patients were improved after the operation.The size of incision,operation time,bleeding,pain,hospital stay,and occurrence of adverse reactions in the single operation port group were superior to those in the double operation port group,with significant differences(P＜0.05).The incidence of active bleeding in the single operation port group was lower than that in the double operation port group,with significant difference(P＜0.05).There was no significant difference in remission of hand sweating and profuse sweat between the two groups (P＞0.05).ConclusionFor patients with palmar hyperhidrosis,application of T3thoracic sympathectomy under single operation port thoracoscope obtains a remarkable effect.It not only reduce hospital stay,but also lowers down the cost of hospitalization in a small incision and high safety,which is worthy to be applied in clinical practice in future.
2017 Vol. 24 (33): 30-32 [Abstract] ( 157 ) HTML (36 KB)  PDF  (0 KB)  ( 72 )
33 Clinical effect observation of tension-free hernia repair in patients with oblique inguinal hernia
XU Wei；SONG Jin-song
ObjectiveTo study the clinical effect of tension-free hernia repair in the treatment of patients with oblique inguinal hernia.MethodsFrom March 2015 to April 2017,90 patients with oblique inguinal hernia were selected and evenly divided into the traditional group and the tension-free group according to random number table method.In the traditional group,traditional hernia repair was used,while in the tension-free group,tension-free hernia repair was adopted.The total amount of bleeding during surgery,mean operation time,time of being off bed,average hospital stay,total therapeutic effectiveness rate,and incidence of complications including hematoma of scrotum were compared between the two groups.The total scores of SF-36 scale before and after treatment were compared between the two groups.ResultsThe total therapeutic effectiveness rate of in the tension-free group was significantly higher than that in the traditional group(P＜0.05).The incidence of complications such as hematoma of scrotum in the tension-free group was lower than that in the traditional group(P＜0.05).The total amount of bleeding,the meane operation time,time of being off bed,and the average hospital stay in the tension-free group were all superior to those in the traditional group (P＜0.05).Before treatment,the scores of SF-36 scale were similar in the two groups(P＞0.05).After treatment,the total scores of SF-36 in the two groups were higher than those before treatment,respectively (P＜0.05).The total score of SF-36 in the tension-free group after treatment was better than that in the traditional group (P＜0.05).ConclusionApplication of tension-free hernia repair is effective in the treatment of patients with indirect inguinal hernia.It can effectively improve the disease condition,reduce the occurrence of complications,speed up the rehabilitation,shorten hospital stay,and improve the quality of life at the characteristics of minimal invasion and safety,which is worthy of promotion.
2017 Vol. 24 (33): 33-35 [Abstract] ( 183 ) HTML (33 KB)  PDF  (0 KB)  ( 39 )
36 Influence of lingual orthodontic treatment on oral function and asthetics
YU Lei
ObjectiveTo explore the influence of lingual orthodontics on the oral function and asthetics of patients.MethodsFrom January 2014 to December 2015,60 outpatients with malocclusion were selected as the objects and randomly divided into the observation group and the control group,30 cases in each group.The control group was treated with labial orthodontic non-extraction treatment,and the observation group was conducted with lingual orthodontics treatment.The influence of two orthodontic techniques on the oral function and appearance of the patients were compared and analyzed.ResultsThe influence degree of the morphological appearance of the observation group was better than that in the control group,with significant difference(P＜0.05).In soft tissue discomfort,all patients of the two groups had different degree of foreign body sensation,but no intolerance was found,and the difference in the two groups was no statistically significant(P＞0.05).In the pronunciation situation,two kinds of technology had statistical significance at the beginning of treatment and the differences within 1 week (P=0.010).In the first 4 weeks,the influence of feeding for patients in the observation group was significantly higher than that in the control group(P＜0.05),and which eased after 4 weeks.ConclusionThe treatment of lingual orthodontics has certain influence on the patients′eating and pronunciation,but it has little effect on the patients′beauty,so it is worth popularizing in clinical practice.
2017 Vol. 24 (33): 36-38转41 [Abstract] ( 168 ) HTML (36 KB)  PDF  (0 KB)  ( 62 )
39 Influence of uninjured upper limb training on upper limb function of hemiplegic limbs
BAI Dan-hua； WEI Li-ping； JIANG Dan ；XU Qing-cui；ZHU Ju-qing
ObjectiveTo study the curative effect of uninjured upper limb training on upper limb function in hemiplegic patients.Methods44 patients with stroke hemiplegia who were hospitalized in our hospital from January 2013 to April 2017 were selected and randomly divided into the treatment group and the control group(n=22).The patients in the two groups were treated with routine rehabilitation training,including hemiplegic limb comprehensive training,hyperbaric oxygen,neuromuscular stimulation,electroacupuncture and so on.On the basis of the above rehabilitation therapy,the treatment group used compensatory ADL training,the control group was Only given the affected side of the body for rehabilitation training,and did not allow healthy side compensation.The two groups of patients were trained 45 min each time,1 times a day,the course of treatment was 30 d.Using the MAS scale in the upper limb motor function score,functional independence(FIM)self-care ability in dressing,grooming,eating and other items evaluated.ResultsThe score of MAS in the treatment group after treatment was significantly higher than that before treatment and the control group after treatment(P＜0.05).There was no significant difference in the FIM index score between the treatment group after treatment and before treatment and the control group after treatment(P＞0.05).ConclusionUpper limb training can improve the motor function of upper limb in stroke patients with hemiplegia.
2017 Vol. 24 (33): 39-41 [Abstract] ( 188 ) HTML (31 KB)  PDF  (0 KB)  ( 39 )
42 Clinical discussion of laparoscopic cholecystectomy in the treatment of acute cholecystitis complicated with gallstones
JIANG Wen-hua； HU Jie ；CAO Feng
ObjectiveTo investigate the clinical effect of laparoscopic cholecystectomy in acute cholecystitis complicated with gallstones.Methods80 cases of cholecystitis with gallstones from January 2014 to December 2015 in our hospital were selected and divided into the control group and the observation group according to case number,40 cases in each group.The patients in the control group were treated with conventional surgery.The patients in the observation group were treated with laparoscopic cholecystectomy.The operative time,blood loss,hospitalization time and recovery time were compared between the two groups,and the incidence of complication was compared between the two groups.ResultsThe operation time,hospitalization time and recovery time of the observation group were shorter than those of the control group,the blood loss of the observation group was less than that of the control group,the incidence of postoperative complications in the observation group was significantly lower than that in the control group,the difference was statistically significant(P＜0.05).ConclusionThe use of laparoscopic cholecystectomy can shorten the timing of surgery for patients with gallstones associated with acute cholecystitis,while reduce postoperative incisional infection and complications.
2017 Vol. 24 (33): 42-44 [Abstract] ( 156 ) HTML (31 KB)  PDF  (0 KB)  ( 42 )
45 Clinical study of Decitabine in the treatment of myelodysplastic syndrome accompanied with DNMT3A gene mutation
PENG Li-ping
ObjectiveTo observe the effect of Decitabine in the treatment of myelodysplastic syndrome(MDS)patients with or without DNMT3A gene mutation.MethodsFrom January 2013 to June 2017,20 MDS patients with DNMT3A gene mutation receivedtreatment in our hospital were selected as the research group.Meanwhile,20 MDS patients without DNMT3A gene mutation was selected as the control group.All patients were treated with Decitabine,and the improvement of the two groups of patients after receiving capecitabine treatment was observed.ResultsThe total clinical effectiveness rate was 65%in the research group,which was significantly higher than that in the control group(35%),with significant difference(P＜0.05).Before treatment,DNMT3A gene expression in the research group was greatly higher than that in the control group(P＜0.05),and the expression of DNMT3A after treatment was markedly decreased(P＜0.05).There was no significant difference in the incidence rate of adverse drug reactions between the two groups(P＞0.05).ConclusionDecitabine in the treatment of MDS with DNMT3A gene mutation can obtain a great effect.For MDS patients with DNMT3A gene mutation,Decitabine is a preferred choice for the treatment.
2017 Vol. 24 (33): 45-47 [Abstract] ( 192 ) HTML (33 KB)  PDF  (0 KB)  ( 63 )
48 Application value of Remifentanil in the cesarean section given with general anesthesia
LI Zhe-qi；ZHONG Ni；LI Rong
ObjectiveTo explore the application value of Remifentanil in the cesarean section given with general anesthesia.Methods32 puerpera given the general anesthesia of cannula in our hospital from January 2016 to March 2017 were selected the study group.At the same period,32 puerperae given the combined spinal-epidural anesthesia were selected the control group.During the process,Remifentanil was used to make the anesthesia induction and maintenance.After surgery,Apgar score in two groups was observed and analyzed,and the change of heart rate and blood pressure between the two groups were compared.ResultsAt the different time point,the heart rate between the two groups was not significantly different(P＞0.05),and at T0,the systolic blood pressure and diastolic blood pressure between the two groups was not significantly different(P＞0.05).From T1to T4,the systolic blood pressure and diastolic blood pressure in the study group was higher than that of the control group respectively(P＜0.05).During surgery,the bleeding volume between the two groups was not significantly different(P＞0.05).Apgar score between the two groups was not significantly different(P＞0.05).ConclusionDuring the general anesthesia of cesarean section,Remifentanil has a higher use value,and it will not produce an obvious effect in the fetal heart rate and respiration,and can effectively inhibit the stress response caused by the intubation and operation,reduce the intraoperative blood loss,and promote the recovery of patients.It is worthy of clinical promotion and application.
2017 Vol. 24 (33): 48-50 [Abstract] ( 208 ) HTML (34 KB)  PDF  (0 KB)  ( 41 )
51 Application of intravenous pump infusion of 0.5 μg/kg Dexmedetomidine in gynecological laparoscopic surgery
ZHANG Yi-long
ObjectiveTo study the application value of intravenous pump infusion of 0.5 μg/kg Dexmedetomidine in gynecological laparoscopic surgery.Methods100 female patients admitted into our hospital from May 2016 to March 2017 were selected as the research objects.All patients were randomly divided into the experimental group and the control group,and there were 50 patients in each group.The patients in the control group were given the routine induction and maintenance anesthesia,while the patients in the experimental group were given intravenous pump infusion of 0.5 μg/kg Dexmedetomidine at about 30 minutes before the end of the operation on the basis of the routine induction and maintenance anesthesia,and it was completed within 15 minutes.The restlessness,sedation,shivering,adverse reactions and cognitive function of the two groups were evaluated during the anesthesia recovery period.ResultsThe score of restlessness,sedation,and shivering in the experimental group were higher than those in the control group[(93.2±2.7)points vs.(78.3±1.8)points;(3.68±0.21)points vs.(1.39±0.11)points;(95.0±3.0)points vs.(78.8±2.1)points],and the differences were statistically significant(P＜0.01).After the operation,the score of the simple mental state evaluation scale in the experimental group was lower than that of the control group [(25.1±0.8)points vs.(28.0±0.5)points],and the differences were statistically significant(P＜0.01).The total incidence of adverse reactions in the experimental group was lower than that in the control group(10.0%vs.32.0%),and the differences were statistically significant(P＜0.05).ConclusionIntravenous pump infusion of 0.5 μg/kg Dexmedetomidine applied in gynecological laparoscopic surgery about 30 minutes before the end of the operation has a significant clinical effect on preventing the restlessness,shivering during general anesthesia awakening period,and has little effect on cognitive function,and can improve the quality of general anesthesia recovery period.
2017 Vol. 24 (33): 51-53 [Abstract] ( 197 ) HTML (34 KB)  PDF  (0 KB)  ( 65 )
54 Anestheticeffectcomparison ofdifferentadministration method of Dexmedetomidine in gynecological laparoscopic surgery
LIAO Xiao-yong
ObjectiveTo compare the anesthetic effect of different administration method of Dexmedetomidine in gynecological laparoscopic surgery.Methods138 patients given with gynecological laparoscopic surgery from November 2013 to November 2016 in our hospital were selected as the research object.The patients were divided into the three groups:group A,B and C according to random number table method,and there were 46 cases in each group.Group C was the control group,group A and B was given Dexmedetomidine single intravenous injection and Dexmedetomidine continuous intravenous infusion respectively.The anesthetic effect and incidence of adverse reactions were compared among the three groups.ResultsHR of group A and group B were significantly lower than that of group C at T1-T5,and MAP of group A was significantly lower than that of group C at T1-T5,while MAP of group B was significantly lower than that of group C at T1and T3-T5,and the differences were statistically significant(P<0.05).The incidence of tachycardia,nausea and vomiting in group A and group B were significantly lower than those in group C(P<0.05),while the incidence of bradycardia in group A was significantly lower than that in group B(P<0.05).ConclusionA single intravenous injection of Dexmedetomidine was performed before induction of anesthesia in gynecologic laparoscopic surgery can reduce the hemodynamic fluctuation,reduce nausea,vomiting and other adverse reactions,and not increase the incidence of bradycardia,and help to promote postoperative recovery of patients.
2017 Vol. 24 (33): 54-56 [Abstract] ( 203 ) HTML (32 KB)  PDF  (0 KB)  ( 52 )
57 Analysis of ultrasound characteristics and ovarian hormone level in patients with premature ovarian failure
WANG Xian-jin
ObjectiveTo study the ultrasonic testing results of patients with premature ovarian failure(POF)and to test their ovarian hormone levels.MethodsFrom January 2016 to July 2017,50 patients with POF examined in our hospital were classified into observation group.Meanwhile,50 normal married women who came to our hospital for physical examinations during the same period were categorized into control group.The difference of ovarian ultrasound examination results was observed and the difference of ovarian hormone levels was determined.ResultsThe size of uterus and ovary,endometrium and concrete number of ovarian follicle were were significantly lower in the observation group than those in the control group,and the differences were statistically significant(P<0.05).Meanwhile,ultrasound detection results displayed high echo in ovary in the observation group,and low echo of ovary in the control group.The peak blood flow velocity of ovarian artery and the minimal blood flow velocity in end-diastole in the observation group were lower than those in the control group,the resistance index and beat index in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The level of serum estradiol in the observation group was significantly lower than that in the control group,the follicle stimulating hormone and luteinizing hormone were significantly higher than the control group,and the differences were statistically significant(P<0.05).ConclusionCompared with normal married women,there are remarkable differences in ultrasound features and ovarian hormone levels in POF patients,such as reduction of uterine and ovarian volume,decrease of follicular amount,peak blood flow velocity of ovarian artery,serum estradiol level,and increase of follicle stimulating hormone and luteinizing hormone levels,and so forth.
2017 Vol. 24 (33): 57-59 [Abstract] ( 159 ) HTML (34 KB)  PDF  (0 KB)  ( 33 )
60 Value of magnetic resonance 3D SPACE sequence combined with DWI sequence in preoperative staging of rectal cancer
XIAO Han-bing； LI Xue-mei ；YE Jian-hui；ZHENG Yi-hong ；LIU Jin-sheng； HE Wen-jun
ObjectiveTo investigate the application value of magnetic resonance three-dimensional sampling perfection with application optimized contrasts using different flip angle evolutions(3D SPACE)sequence combined with magnetic resonance diffusion weighted imaging (DWI)sequences in preoperative staging of rectal cancer.MethodsA total of 38 patients who had rectal cancer were performed in our hospital from September 2016 to December 2017 were selected as subjects of the study.The preoperative magnetic resonance 3D SPACE sequence and DWI sequence examination results were analyzed retrospectively and preoperative T staging and N staging were performed according to the results.The preoperative stage results were compared with postoperative pathological results.ResultsKappa value of 3D SPACE sequence combined with DWI with postoperative pathology in preoperative T staging was 0.78(P=0.000),and the accuracy in T staging was 86.84%.The Kappa value of 3D SPACE sequence combined with DWI with postoperative pathology in preoperative N staging was 0.33 (P=0.000),and the accuracy in N staging was 63.15%.ConclusionMagnetic resonance 3D SPACE sequence combined with DWI can accurately judge the rectal cancer infiltration depth of intestinal wall and improve the accuracy of preoperative staging,providing valuable references for operation of rectal cancer.
2017 Vol. 24 (33): 60-62 [Abstract] ( 168 ) HTML (30 KB)  PDF  (0 KB)  ( 46 )
63 Efficacy observation of fetal systematic ultrasound examination and routine ultrasonography in obstetrics
DONG Lei；LAI Gan-ping； BU Dan
ObjectiveTo incestigate the clinical application effect of fetal systematic ultrasound examinationand obstetric routine ultrasound examination.MethodsFrom January 2015 to January 2017,360 pregnant women who were examined in our hospital were selected as subjects and evenly divided into observation group (n=180)and reference group(n=180)in random.The pregnant women in the observation group were provided with ultrasound examination of the fetal system,those participants in the reference group were provided with obstetric routine ultrasound examinations.The inspection outcomes were compared between the two groups.ResultsThere were 332 normal fetuses and 28 cases of abnormal fetuses.In the observation group,8 cases of malformation fetus were detected from 10 cases,the detection rate was 80%,while in the control group,12 cases of malformation fetus were detected from 18 cases,the detection rate of 66.67%,and the detection rate of observation group was obviously higher than that of control group,the difference was statistically significant(P<0.05).In addition,the total satisfaction in the examination method and results of pregnant women in the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).ConclusionThe detection results by fetal systematic ultrasound examination in pregnant women are better than those of routine ultrasound examination，which can accurately observe the development of the fetus，increase the satisfaction of the pregnant women，and reduce the conflicts between doctors and patients.It is worthy of promotion in future.
2017 Vol. 24 (33): 63-65 [Abstract] ( 168 ) HTML (31 KB)  PDF  (0 KB)  ( 40 )
66 Effects of Alendronate sodium combined with Simvastatin on bone healing after hip fracture internal fixation in elderly patients
GAO Yong ；RAO Fang-ping ；ZHANG Wan-quan； OUYANG Shao-ming ；RAO Yi-kang ；JIN Shao-li
ObjectiveTo investigate the effect of Simvastatin combined with Alendronate sodium on bone healing in elderly patients with hip fracture internal fixation.MethodsForty-six patients with hip fracture and internal fixation who were treated in our hospital from May 2014 to February 2017 were divided into three groups according to the random number method,15 cases in each group.The treatment group was treated with Simvastatin combined with Alendronate sodium,the control group was treated with Alendronate sodium,the blank group was treated with conventional Vitamin D and Calcium Carbonate D3tablets.The healing of hip fractures and the levels of serum bone alkaline phosphatase(BAP)and osteocalcin(BGP)were measured at four time intervals.ResultsThe healing rate of callus at 12 weeks,6 months and 12 months after operation was statistically significant compared with the first week after operation (P<0.05).The healing rate of callus at 12 weeks,6 months after operation in the treatment group was higher than that in the control group and the blank group(P<0.05).The difference of the callus healing rate between the three groups after 12 months was not statistically significant(P>0.05).Compared with preoperative,the levels of BAP were significantly increased in the first week after operation,but the levels of BGP were decreased,but there was no significant difference between the both two groups(P>0.05).After 12 weeks and 6 months,the levels of BAP and BGP in the treatment group were significantly higher than those in the control group and the blank group (P<0.05),There was no significant difference in BAP and BGP between the control group and the blank group(P>0.05).ConclusionSimvastatin combined with Alendronate sodium can be used as an effective option,and anti-osteoporosis treatment is effective,which is conducive to improving bone mass.
2017 Vol. 24 (33): 66-68转84 [Abstract] ( 202 ) HTML (39 KB)  PDF  (0 KB)  ( 43 )
69 Clinical study of Ebastine and Ranitidine combined with Compound Glycyrrhizin Tablets in the treatment of chronic urticaria
YANG Cheng-yu；YU Jin-song
ObjectiveTo investigate the clinical effect of Ebastine and Ranitidine combined with Compound Glycyrrhizin Tablets in the treatment of chronic urticaria.Methods80 patients of Chronic urticaria who were admitted to our hospital from November 2016 to March 2017 were selected.According to the random balancing sequencing method,the patients were divided into control group and observation group,40 cases in each up.The control group was given Ebastine combined with Ranitidine,and the observation group was further given Compound Glycyrrhizin Tablets on the basis of the control group.The serum total IgE level,clinical efficacy,adverse reactions and other related indicators were observed after the treatment.ResultsThe decreasing speed of the level of serum IgE in the observation group was faster than that in the control group,and the clinical curative effect was better than that in the control group;the occurrence of adverse reactions was less than that in the control group,without serious adverse reactions.There was significant difference between the two groups(P<0.05).ConclusionIn the treatment of chronic urticaria,the application of ebastine and ranitidine combined with compound glycyrrhizin tablets can significantly improve the clinical curative effect of patients,with ideal safety,which is worthy of clinical application and promotion in the treatment of urticaria.
2017 Vol. 24 (33): 69-71 [Abstract] ( 212 ) HTML (35 KB)  PDF  (0 KB)  ( 40 )
72 Clinical effect of Liuwei Dihuang Pills combined with Aripiprazole in the treatment of male schizophrenia and its influence on sexual function of male patients
LIU Xun-xiong
ObjectiveTo investigate the clinical effect of Liuwei Dihuang Pills combined with Aripiprazole in the treatment of male schizophrenia and its influence on sexual function of male patients.MethodsFrom January 2015 to March 2016,96 cases of male patients with schizophrenia psychiatric in our hospital were selected as objects,according to the different treatment methods,the selected patients were divided into control group and observation group,There were 48 cases in each group.The control group was treated with Aripiprazole,and the observation group was treated with Liuwei Dihuang Pills on the basis of the treatment of the control group,and the course of treatment was 2 months.The clinical effect of the two groups and the effects on sexual function after treatment were compared,and the adverse reactions of the two groups were recorded.ResultsAfter treatment,observation group PANSS total score [(46.2±16.7)points]were significantly lower in control group[(58.9±15.6)points,]the total score of ASEX [(12.9±6.8)points]was significantly lower in control group[(20.7±6.4)points]and the difference was statistically significant(P<0.05);the total efficiency of the observation group 93.75%(45/48)was significantly higher than the control group 77.08%(37/48)and the total effective comparison of the two groups was statistically significant(P<0.05);the incidence of adverse reactions was 16.67%(8/48),the control group adverse reaction rate was 10.42%(5/48),There was no statistically significant difference between the two groups(P>0.05).ConclusionLiuwei Dihuang Pills combined with Aripiprazole in the treatment of schizophrenia patients can significantly improve the treatment effect,improve sexual dysfunction,and less adverse drug reactions,it is worthy of clinical application.
2017 Vol. 24 (33): 72-74 [Abstract] ( 205 ) HTML (35 KB)  PDF  (0 KB)  ( 59 )
75 Clinical effectand safety of low dose Mirtazapine combined with Duloxetine in the treatment of senile refractory depression
JIANG Shen-hui；YE Qing
ObjectiveTo investigate the clinical effect and safety of low dose Mirtazapine combined with Duloxetine in the treatment of senile refractory depression.Methods88 elderly patients with refractory depression in our hospital during the period from May 2015 to August 2016 were selected,and randomly divided into two groups according to the random number table method,the observation group (44 cases)and control group (44 cases).The control group were treated with Duloxetine treatment,the observation group were treated with small dose of Mirtazapine on the basis of control group,patients of two group were treated for two months.The scores of anxiety and depression,the clinical effect and adverse reactions were compared.ResultsThe scores of HAMA,HAMD and CGI-SI in the observation group were significantly lower than those in the control group after 2 weeks,5 weeks and 7 weeks,the difference was statistically significant(P<0.05).The TESS score of the observation group was(1.78±0.36)points,compared with the control group[(1.86±0.47)points],there was no statistically significant difference (P>0.05).The incidence of adverse reactions in observation group was 4.55%,compared with the control group 6.82%,showed no significant difference (P>0.05).The total effective rate in the observation group was 93.18%,significantly higher than the control group(72.72%),the difference was statistically significant(P<0.05).ConclusionFor elderly refractory depression patients,the combination of low-dose Mirtazapine and Duloxetine can achieve better therapeutic effect,and will not increase the incidence of adverse drug reactions.It is worth popularizing.
2017 Vol. 24 (33): 75-77 [Abstract] ( 197 ) HTML (33 KB)  PDF  (0 KB)  ( 39 )
78 Clinical observation on Dydrogesterone Tablets in the treatment of threatened abortion caused by luteal insufficiency
FENG Liu-huan
ObjectiveTo investigate the clinical efficacy of Dydrogesterone Tablets in the treatment of threatened abortion due to luteal insufficiency.MethodsA total of 60 cases of luteal insufficiency complicated with threatened abortion who admitted to our hospital were collected as the study subjects from June 21,2015 to June 20,2016.The patients were grouped in accordance with the order of admission.The experimental group was given Dydrogesterone Tablets for treatment,and the routine group was given Progesterone Injection for treatment.The treatment effect of two groups of patients was compared.ResultsThe success rate of preventing miscarriage in experimental group and routine group was 90.00%and 86.67%respectively,there was no statistically significant difference (P>0.05);the incidence rate of adverse reactions in experimental group and routine group was 16.67%and 56.67%respectively,the difference was statistically significant(P<0.05);after treatment,the levels of serum P and E2in the experimental group after the treatment were significantly better than those in the routine group,the difference was statistically significant(P<0.05).ConclusionThe treatment of threatened abortion due to luteal insufficiency by Dydrogesterone Tablets has a significant effect,which has a high drug safety and is easy to improve the clinical symptoms of patients.It is worth wide application in the clinical.
2017 Vol. 24 (33): 78-80 [Abstract] ( 176 ) HTML (35 KB)  PDF  (0 KB)  ( 58 )
81 Clinical effect comparison of Desogestrel and Ethlinylestradiol Tablets and Medroxyprogesterone in the treatment of adolescent dysfunctional uterine bleeding
LIU Zhi-hua
ObjectiveTo compare the clinical effect of Desogestrel and Ethlinylestradiol Tablets and Medroxyprogesterone in the treatment of adolescent dysfunctional uterine bleeding in order to provide a scientific basis for the drug choice of clinical treatment.MethodsFrom March 2015 to March 2017,52 patients with adolescent dysfunctional uterine bleeding treated by Medroxyprogesterone in our hospital were selected into control group.Meanwhile,52 patients with adolescent dysfunctional uterine bleeding treated by Desogestrel and Ethlinylestradiol Tablets in our hospital were classified into observation group.The clinical effect by the two different methods was compared.ResultsThe total effectiveness rate was 98.0%in the observation group,much higher than that in the control group accounting for 82.7%(χ2=6.172,P<0.05).Compared with the control group,the improvement of endometrial thickness,menstrual cycle,volume of menses after therapy was all more remarkable(t=3.168,t=32.413,t=11.607;P<0.05).The incidence of adverse reactions in the observation group was 9.6%,much lower than that in the control group accounting for 32.7%(χ2=17.146，P<0.05).ConclusionFor adolescent dysfunctional uterine bleeding,both Desogestrel and Ethlinylestradiol Tablets and Medroxyprogesterone can obtain a certain effect,and is better in the former which has a lower incidence of adverse reactions and a more reliable safety in clinical application after comparison.Desogestrel and Ethlinylestradiol tablets is worthy to be widely promoted in clinical application.
2017 Vol. 24 (33): 81-84 [Abstract] ( 132 ) HTML (37 KB)  PDF  (0 KB)  ( 62 )
85 Early diagnostic value and clinical significance of procalcitonin in patients with chronic obstructive pulmonary disease complicated with heart failure complicated with pulmonary infection
YAO Zhi-qiang；HUANG Gui-qiong；YUAN Wei-wei；ZHANG Xu-mei

ObjectiveTo investigate the value of procalcitonin in the early diagnosis and clinical significance of chronic obstructive pulmonary disease complicated with heart failure accompanied by pulmonary infection.MethodsChoose from January 2016 to May 2017 in our hospital accepts patients with 60 cases,complicated with heart failure with pulmonary infection in 20 cases,as the observation group,only 20 cases have heart failure as the reference group,20 healthy cases as control group.The procalcitonin level and the detection of pathogens in the three groups were observed.ResultsThe difference in calcitonin level between the three groups was statistically significant(P<0.05).Famian detected in pathogenic bacteria,chronic obstructive pulmonary disease complicated with heart failure in patients with lung infection there was a variety of pathogenic bacteria,gram negative bacteria were mainly;and the gram negative bacteria and gram positive bacteria group comparison,the procalcitonin levels also showed significant differences(P<0.05);at the same time in different levels in patients with chronic obstructive pulmonary disease,procalcitonin levels also had significant difference.ConclusionThere is a significant difference in procalcitonin levels in patients with chronic obstructive pulmonary disease complicated with heart failure accompanied by pulmonary infection,and clinical treatment can be carried out according to the level of procalcitonin.
2017 Vol. 24 (33): 85-87 [Abstract] ( 146 ) HTML (36 KB)  PDF  (0 KB)  ( 43 )
88 Effect analysis of Atorvastatin Calcium in different doses in the treatment of acute cerebral infarction
CHENG Guo-hui；LI Wen-dong ；QIAN Jian-ning
ObjectiveTo investigate the effect of different doses of Atorvastatin Calcium in the treatment of acute cerebral infarction(ACI).MethodsFrom June 2014 to July 2016,150 ACI patients admitted to our hospital were selected as research subjects.According to different dosage of atorvastatin calcium,they were evenly divided into three groups(10 mg,20 mg,and 40 mg)50 cases in each group.The medication was continued for 90 days.The indicators of low density lipoprotein cholesterol(LDL),total cholesterol(TC),triglyceride(TG),high sensitivity C-reactive protein(hs-CRP),intima-medial thickness(IMT),high density lipoprotein cholesterol(HDL),stroke scale(NIHSS),creatinine(Cr),uric acid(UA),blood urea nitrogen (BUN),and white blood cell(WBC)were compared before treatment,30 day,and 90 day after treatment.ResultsThe 30 day and 90 day treatments was compared with prior treatment,the levels of LDL,TC,and TG in three groups were all decreased significantly(P<0.05).However,after the treatment of 90 days,the LDL and TC levels in the 20 mg and 40 mg groups were significantly different than those in the 10 mg group(P<0.05).There was great difference in HDL level among three groups(P<0.05),while for TG level,it was not significant(P>0.05).After treatment for 30 and 90 days,the NIHSS scores were displayed statistical differences in comparison with that prior treatment among three groups(P<0.05).The score in 20mg and 40 mg groups was greatly different from that in 10mg group after 90 day treatment,but for the comparison of 20 mg and 40 mg groups,they were not obvious(P>0.05).After 30 day therapy,thehs-CRP level in 20 mg and 40 mg groups was displayed a statistical difference compared with that in 10mg group(P<0.05),but no statistical significance between 20 mg group and 40 mg group(P>0.05).On day 90,there was no significant difference in hs-CRP level among three groups (P>0.05).No significant change was detected in IMT,Cr,UA,BUN,or WBC before and after treatment among three groups(P>0.05).ConclusionAtorvastatin calcium in 20 mg can treat ACI in safe and effective,also reduces the hs-CRP level.
2017 Vol. 24 (33): 88-90 [Abstract] ( 171 ) HTML (33 KB)  PDF  (0 KB)  ( 51 )
91 Clinical efficacy of early combined application of Clopidogrel and Butyphthalide Soft Capsules in the treatment of cerebral infarction
LI Yuan
ObjectiveTo analyze the clinical efficacy of early combined application of Clopidogrel and Butylphthalide Soft Capsule in the treatment of cerebral infarction.MethodsA total of 90 patients with cerebral infarction who were admitted to our hospital from May 2016 to May 2017 were randomly selected as the subjects of this study.The patients were divided into the control group and the observation group according to the method of random number table,with 45 patients in each group.The control group was given routine treatment after inclusion and confirmed diagnosis,including neuroprotection,dehydration for the reduction of intracranial pressure,elimination of free radicals,statin for lipid adjustment,etc,and Clopidogrel was used for combined application.The patients in the observation group were given early application of Clopidogrel combined with Butylphthalide Soft Capsules on the basis of the control group.The follow-up visit was for a one month.The differences of the clinical efficacy,neurological function and daily living ability were compared between the two groups.ResultsThe total effective rate was 93.33% (42/45)in the observation group,which was significantly higher than that in the control group 68.89%(31/45),and there was significant difference between the two groups,which was statistically significant(P<0.05).There was no significant difference in NIHSS score and ADL score between the two groups before treatment,and it was not statistically significant(P>0.05);the NIHSS score was[(6.3±1.2)points]in the observation group in the last follow-up visit,which was significantly lower than that in the control group.ADL score was[(68.3±5.2)points],which was significantly higher than that in the control group,and the difference was statistically significant(P<0.05).ConclusionThe clinical efficacy of the early combined application of Clopidogrel and Butylphthalide Soft Capsules in the treatment of cerebral infarction is exact,and plays a positive role in improving the degree of neurological deficits in patients,and improving the ability of daily activities,which is worthy of promotion in clinical practice.
2017 Vol. 24 (33): 91-93 [Abstract] ( 166 ) HTML (31 KB)  PDF  (0 KB)  ( 70 )
94 Clinical observation of Octreotide and Omeprazole in the treatment of acute pancreatitis
GONG Li-ping ；XIAO Qing-hua ；LI Yu-ping
ObjectiveTo investigate the efficacy of Octreotide and Omeprazole in the treatment of acute pancreatitis.Methods124 patients with acute pancreatitis treated in our hospital from March 2011 to February 2017 were selected.According to the order of admission,the patients were randomly divided into the control group and the observation group according to the parity grouping method.Each group had 62 cases.The control group was treated with Octreotide,and the observation group was treated with Octreotide combined with Omeprazole.The therapeutic effects,clinical symptoms and signs,normal time and adverse reaction rate were compared between the two groups.Resultsin total clinical efficacy,the observation group was significantly higher than the control group,with statistical significance (P<0.05).The observation group was significantly better than the control group in the clinical symptoms and the recovery of the physical signs,with statistical significance (P<0.05).In the incidence of adverse reactions,the difference between the observation group and the control group was not significant,which was not statistically significant(P>0.05).ConclusionOctreotide combined with Omeprazole is effective in the treatment of acute pancreatitis,which is helpful for the improvement of clinical symptoms and the low incidence of adverse reactions.It is worth popularizing.
2017 Vol. 24 (33): 94-96 [Abstract] ( 125 ) HTML (34 KB)  PDF  (0 KB)  ( 35 )
97 Effect of Danhong Injection combined with Cinepazide Maleate in the treatment of coronary heart disease complicated with angina pectoris
LI Nan
ObjectiveTo investigate the value of combined treatment of Danhong Injection and Cinepazide Maleate in the patients with coronary heart disease complicated with angina pectoris.MethodsThe 120 cases of coronary heart angina patients who were treated in our hospital from January 20,2015 to February 23,2017 were selected.According to the difference of their treatment measures,they were divided into the experimental group and the control group,with 60 cases in each group.In the control group were given aspirin,atorvastatin,nitroglycerin and other conventional treatment,and in the experimental group were given Danhong Injection combined with Cinepazide Maleate at the same time.The differences of total effective rate,blood viscosity,platelet aggregation levels,adverse reactions and other indicators were compared between the two groups of patients with coronary heart disease complicated with angina pectoris.ResultsThe total effective rate(95.00%)in the experimental group was significantly higher than that in the control group(75.00%)(P<0.05);there were statistically significant differences in blood viscosity and platelet aggregation between the two groups after treatment(P<0.05);there was no statistically significant difference in the adverse reactions between the two groups(P>0.05).ConclusionThe combined treatment of Danhong Injection and Cinepazide Maleate in the patients with coronary heart disease complicated with angina pectoris can achieve better effects and improve the prognosis of patients.
2017 Vol. 24 (33): 97-99 [Abstract] ( 138 ) HTML (34 KB)  PDF  (0 KB)  ( 67 )
100 Clinical study of electroacupuncture on gastrointestinal hormone and gastric emptying role in patients with diabetic gastroparesis
CHEN Hong；LIN Guo-hua
ObjectiveTo investigate the efficacy of electroacupuncture treating diabetic gastroparesis(DGP)and its effect on gastrointestinal hormone and gastric emptying role.MethodsEighty-nine patients with DGP treated in our hospital from May 2014 and March 2017 were included in this study and randomly grouped based on a random number table method.All patients were given hypoglycemic therap,and the control group (n=45)was combined with Mosapride Tablets,while the observation group(n=44)was combined with electroacupuncture.14 days were one course of treatment.Clinical efficacy was compared between the two groups.ResultsAfter treatment,total symptom score of patients reduced in the two groups,which was more obvious in the observation group (P<0.05).After treatment,gastric emptying rate in both groups showed no significant difference(P＞0.05).Serum gastrin(GAS),motilin(MTL)and serum somatostatin(SS)level were decreased after treatment in the two groups,which was more evident in the observation group (P<0.05).Total effective rate in the observation group was higher than that in the control group (90.91%vs.71.11%)(P<0.05).ConclusionElectroacupuncture presents good efficacy in DGP,and can effectively regulate gastrointestinal hormone,therefore,it is worthy of promotion.
2017 Vol. 24 (33): 100-102 [Abstract] ( 158 ) HTML (35 KB)  PDF  (0 KB)  ( 46 )
103 Clinical effect of qi-boosting and blood invigorating herbs on early recovery of ischemic stroke
XIE Rui-tian； HUANG Ze-hong； CAI Jie-na
ObjectiveTo explore the clinical effect of qi-boosting and blood invigorating herbs on early recovery of ischemic stroke.MethodsFrom January to December 2016,60 patients with ischemic stroke treated in our hospital were selected.According to different intervention methods,they were evenly divided into treatment group (n=30)and control group(n=30).In patients of the control group,routine neurology drug therapy,routine nursing,and rehabilitation treatment were applied.Besides that,modified Buyang Huanwu Decoction was added.The incidence of SAP,NIHSS score,modified Barthel index score,CD3+,CD4+,and CD8+,and the ratio of CD4+to CD8+were considered as outcomes indicators.SPSS 20.0 package was used for statistical analysis.ResultsThere was a statistical difference in the incidence of SAP between the two groups(P<0.05).NIHSS score,modified Bathel index score,CD3+,CD4+,and CD8+,and the ratio of CD4+to CD8+before and after treatment were all displayed statistical differences intra group comparison in two groups(P<0.05).There was a statistical difference of NIHSS score,modified Bathel index score,CD3+,CD4+,and CD8+,and the ratio of CD4+to CD8+after treatment between the two groups (P<0.05).ConclusionQi-boosting and blood invigorating herbs can improve symptoms of neurological deficit of patients and reduce the incidence of SAI in patients.
2017 Vol. 24 (33): 103-105 [Abstract] ( 187 ) HTML (38 KB)  PDF  (0 KB)  ( 42 )
106 Evaluation on the effect of Huoxue Huayu Decoction combined with massage in the treatment of limb swelling at the late stage of fracture
LI Shun-ling
ObjectiveTo evaluate the effect of Huoxue Huayu Decoction combined with massage in the treatment of limb swelling at the late stage of fracture.MethodsA total of 70 patients with limb swelling at the late stage of tumor admitted into our hospital from February 2013 to March 2016 were selected.The patients were randomly divided into the two groups according to the computer randomization grouping methods.35 patients in the control group were given Huoxue Huayu Decoction,and 35 patients in the observation group were given Huoxue Huayu Decoction combined with massage.The total effective rate after treatment,the total incidence rate of complications,length stay,the time of symptom improvement,the time of swelling elimination were compared in patients between the two groups.ResultsThe total effective rate in the patients was 91.43%in the observation group,which was higher than that in the control group(74.29%),and the difference was statistically significant(P<0.05).The total incidence rate of complications in the observation group was 11.43%,which was lower than that in the control group (31.43%),and the difference was statistically significant(P<0.05).The length of stay,the time of symptom improvement and the time of swelling elimination in patients of the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).ConclusionHuoxue Huayu Decoction combined with massage in the treatment of limb swelling at the late stage of fracture not only can shorten the length stay,the time of symptom improvement,and the time of swelling elimination,but also improve the treatment effect,which is worthy of further promotion and application.
2017 Vol. 24 (33): 106-107转110 [Abstract] ( 149 ) HTML (30 KB)  PDF  (0 KB)  ( 60 )
108 Application effect observation of Huoxue Zhitong Decoction combined with traditional Chinese medicine rehabilitation therapy in patients with limb swelling at early stage after fracture
WAN Chang-hao；WAN Zhong
ObjectiveTo investigate application effect of Huoxue Zhitong Decoction combined with traditional Chinese medicine (TCM)rehabilitation therapy in patients with limb swelling at early stage after fracture.Methods80 patients with limb swelling at early stage after fracture treated in our hospital from March 2015 to September 2016 were selected.According to the random number method,those patients were divided into the control group (n=40)and the research group(n=40).The control group was given Mannitol and TCM rehabilitation therapy,while the research group was Huoxue Zhitong Decoction combined with traditional Chinese medicine rehabilitation therapy.The curative effect and satisfaction degree score were compared between the two groups.ResultsAfter treatments,the total effective rate of the research group was 95.00%,which was higher than that of the control group (80.00%),and the difference between groups were statistically significant(P<0.05).The satisfaction degree score in the research group[(88.2±2.3)points]was statistically higher than that of the control group [(71.3±1.3)points],and the difference between groups were statistically significant(P<0.05).ConclusionClinical treatment of limb swelling at early stage after fracture can be considered to be given Huoxue Zhitong Decoction combined with TCM rehabilitation therapy,and its effect is outstanding,patients′satisfaction degree is high,it is worthy of clinical application and promotion.
2017 Vol. 24 (33): 108-110 [Abstract] ( 158 ) HTML (30 KB)  PDF  (0 KB)  ( 44 )
111 Significance of myocardial necrosis markers as joint detections in early diagnosis and differential diagnosis of acute myocardial infarction
QIU Ye
ObjectiveTo analyze the significance of myocardial necrosis markers as joint detections in the early diagnosis and differential diagnosis of acute myocardial infarction(AMI).Methods100 patients with suspected AMI from May 2015 to May 2017 in our hospital were selected as the subjects.According to outcomes of B ultrasound and electrocardiography,they were evenly divided into the research group (AMI group)and the control group (non-AMI group).Tests for myocardin and enzymatic activity were performed in the two groups.The creatine kinase (CK)and creatine kinase-MB(CK-MB)were examined by immunosuppression.The indexes of troponin I(cTnI)and myohemoglobin(MYO)were tested by chemiluminiscence.The levels of myocardial enzyme markers were observed and compared in the two groups.The changes of various myocardial necrosis markers at different times in the research group were also observed.ResultsThe levels of myocardial enzyme markers including CK,CK-MB,cTnI,and MYO in the research group were significantly higher than those in the control group,with statistical difference (P＜0.05).The levels of CK and CK-MB in the research group were significantly increased at 3 h and 6 h,and reached the peak value at one day.After 3 to 5 d treatment,the levels mentioned above were in gradual recovery.The levels of cTnI and CK-MB were synchronized one hour before the onset of disease,but the maintenance time in the blood was relatively shorter.The abnormality of MYO was occurred within 2 hours after the onset of disease,and reached the peak in 12 h.ConclusionFor AMI patients,joint detections of myocardial necrosis markers has a favorable diagnostic value,and it is worthy of reference.
2017 Vol. 24 (33): 111-113 [Abstract] ( 180 ) HTML (32 KB)  PDF  (0 KB)  ( 67 )
114 Clinical significance of PCT and CRP in the early diagnosis of urinary tract infection in patients with BPH
HUANG Xin； XU Xiu-rong；KE Gui-bao
ObjectiveTo study the early diagnostic value of C-reactive protein(CRP)and procalcitonin(PCT)in urinary tract infection(UTI)in patients with benign prostatic hyperplasia(BPH).MethodsA prospective study was performed on 77 patients with suspected UTI with BPH in our hospital.According to the urine bacterial culture results,77 cases were divided into infection group(n=49)and control group(n=28).The sensitivity and specificity of CRP and PCT in the diagnosis of UTI patients with BPH,and their correlation were evaluated.ResultsThere was significant difference in CRP and PCT levels between two groups(P<0.01).The area under ROC curve was 0.805 for CRP and 0.859 for PCT respectively in UTI patients with BPH.The sensitivity and specificity of CRP and PCT in the diagnosis of UTI patients with BPH were 89.7%and 87.6%,and 60.7%and 71.4%,respectively.The correlation efficient between CRP and PCT was 0.509(P<0.01).ConclusionSerum levels of CRP and PCT increase in UTI patients with BPH,the detection of serum CRP and PCT levels is helpful to early diagnosis the UTI patients with BPH.
2017 Vol. 24 (33): 114-116 [Abstract] ( 160 ) HTML (30 KB)  PDF  (0 KB)  ( 38 )
117 Application value of HbA1c and BNP in the clinical diagnosis of diabetes mellitus complicated with chronic heart failure
YUAN Guang-yong
ObjectiveTo investigate the application value of HbA1c and BNP in the diagnosis of diabetes mellitus complicated with chronic heart failure.MethodsFrom September 2014 to January 2016,90 patients with type 2 diabetes mellitus complicated with heart disease in our hospital were selected and divided into the control group and the observation group according to whether combined with chronic heart failure,45 cases in each group.The levels of HbA1c and BNP in the two groups and the correlation between HbA1c and BNP levels in the observation group were observed.Results The levels of BNP and HbA1c in the observation group were significantly higher than those in the control group,with significant difference (P＜0.05).There was significant difference in the level of BNP and HbA1c between the gradeⅡ,Ⅲ,Ⅳ of cardiac function in the observation group(P＜0.05),the level of BNP with the HbA1c level increased gradually increases,which showed positive correlation (r=0.77,P＜0.001).ConclusionHbA1c and BNP have important reference value to clinical diagnosis,curative effect evaluation and prognosis of diabetes for the patients with diabetes mellitus complicated with chronic heart.
2017 Vol. 24 (33): 117-119 [Abstract] ( 150 ) HTML (31 KB)  PDF  (0 KB)  ( 73 )
120 Effect of serum homocysteine in the severity and diagnosis of patients with hypertension
CHEN Shu-hua
ObjectiveTo study the effect of serum homocysteine (Hcy)in the severity and diagnosis of hypertensive patients.MethodsA total of 80 hypertensive patients in our hospital from January 2016 to August 2017 were selected as the experimental group,including 23 patients with gradeⅠhypertension,40 patients with gradeⅡhypertension and 17 patients with gradeⅢhypertension.80 healthy volunteers in the same period were selected as the control group.The levels of serum Hcy of each group were observed and compared.ResultsThe level of serum Hcy in the experimental group was significantly higher than that in the control group,the level of serum Hcy in patients with gradeⅠhypertension in the experimental group was lower than that in gradeⅡhypertensive patients which was lower than that in gradeⅢ hypertensive patients,the difference was statistically significant(P＜0.05).The percentage of patients with high Hcyemia was 81.25%in the experimental group,which was significantly higher than that in the control group(15.00%),and the difference was statistically significant(P＜0.05).The higher the level of hypertension,the higher the percentage of patients with high Hcyemia(P＜0.05).ConclusionSerum Hcy levels have a key role in the severity and diagnosis of hypertensive patients.The higher the blood pressure,the greater the risk of high Hcyemia,and the higher the level of Hcy in the patient′s serum.Therefore,monitoring serum levels of Hcy in patients with hypertension diagnosis and treatment of patients is of great significance.
2017 Vol. 24 (33): 120-122 [Abstract] ( 162 ) HTML (33 KB)  PDF  (0 KB)  ( 80 )
123 Influence of improving process management on the work efficiency of nursing management and patients′satisfaction degree in operation room
FANG Liang； ZHENG Qin
ObjectiveTo explore the application value of improving process management in nursing management of the operation room,and the influence on work efficiency and patients′satisfaction degree.MethodsThe sitution of 90 patients undergoing surgical treatment in our hospital from March 2015 to March 2017 were analyzed retrospectively,according to whether to improve the process management group,patients were divided into the control group and observation group,and there were 45 cases in each group.The control group was given the routine nursing,while the observation group was given the improving process management on the basis of the routine nursing.After 7 days,the nursing quality and satisfaction degree between the two groups were compared.ResultsThe score of nursing care,hygiene disinfection,nursing record,surgical environment and instrument management score and overall score of the observation group was higher than that of the control group,and there was a statistical significance(P<0.05).The total satisfaction degree of the observation group was 95.56%,which was higher than that of the control group(73.33%)(P<0.05).ConclusionImproving process management applied in the operation room has a great significance,which can improve the nursing quality and promote the harmony of nurse and patient.
2017 Vol. 24 (33): 123-125 [Abstract] ( 158 ) HTML (32 KB)  PDF  (0 KB)  ( 42 )
126 Study on the application of integrated management of doctors and nurses preventing nosocomial infection in neurosurgery
NI Dan
ObjectiveTo explore the prevention and control effect of integrated management of doctors and nurses in inpatients of neurosurgery.Methods100 inpatients in neurosurgery of the Fourth Affiliated Hospital of Nanchang University of three-level and first class general hospital was selected from August 2016 to August 2017 and they were grouped according to even and odd-numbered of their admission time sequence.The control group was given the the routine medical care mode management,while the observation group was given the integrated management of doctors and nurses.The incidence of nosocomial infection and the satisfaction degree of patients were compared between the two groups,and the accuracy of hand washing and compliance of hand hygiene among medical staff in the observation group before and after intervention were compared.ResultsThe incidence of nosocomial infection in the observation group(4.00%)was lower than that of the control group(20.00%),and there was a statistical difference(P<0.01).In the observation group,before intervention,the accuracy rate of six-step hand-washing method was 88.9%and compliance was 81.15%,after intervention,the above-mentioned indexes was 100.0%and 95.86%respectively,and there was a statistical difference before and after intervention (P<0.01).The total satisfaction degree of the observation group was 90.00%for department,which was significantly higher than of the control group(60.00%),and the difference was statistically significant(P<0.01).ConclusionIntegrated management of doctors and nurses applied in inpatients of neurosurgery can effectively control the rate of nosocomial infection,improve the life quality and satisfaction degree of patients,and improve the compliance of hand hygiene for medical staff.
2017 Vol. 24 (33): 126-128 [Abstract] ( 175 ) HTML (33 KB)  PDF  (0 KB)  ( 67 )
129 Construction of learning style in mixed flipped classroom based on national resource sharing platform
LIN Yi-hua；WANG Er-li；GUO Su-hua
In view of the characteristics and teaching status ofPractical Technology of Chemistry of Chinese Materia Medicain traditional Chinese medicine specialty of higher vocational college,the paper took the extraction and separation technology of flavonoids as an example based on the national resource sharing platform,and tried to construct the learning style of mixed flipped classroom in this class.The learning style is mainly composed of three sections:theoretical study,case analysis,and practical operation.It is divided into three parts including pre-class autonomous learning,discussion teaching in class,and evaluation and feedback after-class,which can stimulate students′learning motivation and improve their practical skills.It is expected to provide new ideas for the reform of the course ofPractical Technology of Chemistry of Chinese Materia Medicain traditional Chinese medicine specialty of higher vocational colleges.
2017 Vol. 24 (33): 129-132 [Abstract] ( 134 ) HTML (36 KB)  PDF  (0 KB)  ( 42 )
133 Application of PBL combined with multi-media teaching mode in pediatric practice teaching
KE Ji-chao
ObjectiveTo analyze the application effect of PBL combined with multi-media teaching mode in pediatric practice teaching.Methods98 pediatric interns recruited in our hospital from July 20,2015 to March 11,2016 were selected and randomly divided into the two groups:the control group (49 cases)was given conventional teaching mode and the observation group(49 cases)was given the PBL combined with multi-media teaching mode.The post-teaching selfevaluation score,operation skill performance and theoretical knowledge performance pediatric interns between the two groups were compared.ResultsThe self-assessment score:satisfaction of teaching mode,ability of thinking and discrimination,clinical skills,independence and initiative of learning and interest in learning core of the observation group were higher than those of the control group (P<0.05).The operation skill score [(90.21±1.05)points]and theoretical knowledge points[(92.21±1.11)points]of observation group were higher than those of control group(P<0.05).ConclusionApplication of PBL combined with multi-media teaching mode in pediatric practice teaching not only can improve the interns′autonomous learning ability and enthusiasm for learning,but also increase the performance of operation skills and theoretical knowledge,which promote the interns′clinical thinking ability.
2017 Vol. 24 (33): 133-135 [Abstract] ( 141 ) HTML (33 KB)  PDF  (0 KB)  ( 67 )
136 Application effect of scenario simulation teaching method in nursing teaching in psychiatry department
QIN Tao；LYU Yun-huo；XIA Xue-bin
ObjectiveTo analyze the application effect of scenario simulation teaching method in nursing teaching in psychiatry department.Methods120 nursing students of nursing department in our college from February to June 2017 were randomly selected and divided into the two groups,and there were 60 cases in each group.The control group was given the traditional indoctrinating teaching,while the observation group was given scenario simulation teaching method.The result of examination and comprehensive ability were compared between the two groups.ResultsThe score of theoretical knowledge and operating skill in the observation group was(88.37±7.66)points,(89.64±6.29)points respectively,which was obviously higher than that of the control group[(72.69±5.28)points,(73.52±5.73)points]respectively,and there was a statistical difference(P<0.05).The score of comprehensive ability in the observation group were higher than those in the control group,and there was a statistical difference (P<0.05).ConclusionScenario simulation teaching method in psychiatry department can increase quality of teaching,enhance comprehensive ability of nursing students,so as to provide the guarantee for the quality of nursing work.
2017 Vol. 24 (33): 136-138 [Abstract] ( 156 ) HTML (34 KB)  PDF  (0 KB)  ( 37 )
139 Effects of meridian nursing on sleep and life quality in patients receiving chemotherapy for lung cancer
XIE Yan；LI Hui；XIONG Han-peng
ObjectiveTo investigate the effect of meridian nursing on sleep and life quality in patients receiving chemotherapy for lung cancer.Methods98 patients with lung cancer who treated in our hospital from May 2016 to May 2017 were divided into the observation group and control group according to the random number table,49 cases in each group.The control group was treated with routine care,while the observation group was given the meridian nursing plus routine care at the same time.Sleep and life quality in two groups were compared before and after treatment.ResultsBefore nursing,the each index scores and total scores of sleep quality and life quality of the patients in the two groups were compared,and the differences were not statistically significant(P<0.05).After nursing,the each index scores and total scores of sleep quality of the patients in the observation group were significantly lower than those in the control group,and the differences were statistically significant(P<0.05).While the each index scores and total scores of life quality of the quality of the patients in the observation group were significantly higher than those in the control group,and the differences were statistically significant(P<0.05).ConclusionThe meridian nursing can effectively improve the sleep and life quality of patients under lung cancer chemotherapy.It is worth promoting clinical application.
2017 Vol. 24 (33): 139-141转156 [Abstract] ( 155 ) HTML (34 KB)  PDF  (0 KB)  ( 33 )
142 Application study of family-centered nursing model in transcatheter closure of children with congenital heart disease
ZHANG Zheng1 WAN Shu1 AI Ling-yun2▲
ObjectiveTo investigate the application effect of family-centered nursing model in transcatheter closure of children with congenital heart diseases(CHD).MethodsFrom April 2015 to March 2017,80 CHD children undergone transcatheter closure treated in the department of heart disease center in our hospital were evenly divided into observation group and control group according to a random number table,40 cases in each group.In the control group,routine nursing was received,while in the observation group,on the basis of routine nursing,family-centered nursing model was added.The perioperative anxiety and the incidence of complications were compared between the two groups.ResultsThere was no significant difference in anxiety scores between the two groups(P>0.05).In the observation group,the anxiety scores at the morning of surgery day and being discharged were both lower than those in the control group,and the differences were statistically significant(P<0.05).The incidence of complications in the observation group was greatly lower than that in the control group,and the differences were statistically significant(P<0.05).ConclusionThe family-centered nursing model can effectively alleviate the anxiety level of CHD children undergone transcatheter closure and decrease the incidence of complications.
2017 Vol. 24 (33): 142-144 [Abstract] ( 150 ) HTML (35 KB)  PDF  (0 KB)  ( 37 )
145 Application effect of individualized nursing intervention combined with health education in patients with fungal vaginitis
LUO Gui-fen； CHENG Li
ObjectiveTo investigate the application effect of individualized nursing intervention combined with health education in patients with fungal vaginitis.Methods96 cases of fungal vaginitis treated in our hospital from January 2015 to December 2016 were randomly divided into the observation group and the control group,48 cases in each group.The control group was given routine care,the observation group was given individualized care,combined with health education.The clinical efficacy,treatment compliance,recurrence rate and the self-care ability of the two groups was compared.ResultsThe total effective rate in the observation group was 95.83%,which was higher than that of the control group(77.08%),the difference was statistically significant(P<0.05).The treatment compliance rate in the observation group was 93.75%,which was significantly higher than that of control group (68.75%),the difference was statistically significant(P<0.05).The the recurrence rate after treatment in the observation group was 8.33%,which was significantly lower than that of the control group (29.17%),the difference was statistically significant(P<0.05).The patients self-care ability scores in the observation group were significantly higher than the control group,the differences were statistically significant(P<0.05).ConclusionThe effect of individual nursing care combined with health education on mycotic vaginitis patients,can significantly improve the clinical treatment effect,promote the rehabilitation of patients,and to improve the treatment compliance of patients,reduce the recurrence rate has important application value.
2017 Vol. 24 (33): 145-147 [Abstract] ( 168 ) HTML (32 KB)  PDF  (0 KB)  ( 44 )
148 Effect of comprehensive nursing intervention on the anxiety and depression in the treatment of assisted reproductive technolog
LIAO Guang-hua
ObjectiveTo investigate the effect of comprehensive nursing intervention on the anxiety and depression in the treatment of assisted reproductive technology.MethodsFrom January 2016 to January 2017,80 cases of infertility patients who treated in our hospital with assisted reproductive help pregnant were selected as subjects,and according to patients′personal wishes,they were divided into the control group(n=38)and the observation group(n=42).The patients of control group were treated with routine care and reproductive technology treatment,the patients of observation group were given comprehensive nursing intervention based on the control group.The anxiety self-rating scale(SAS)score,the depression self-rating scale (SDS)score and the pregnancy outcome of the two groups were compared.ResultsAfter nursing,the SDS and SAS scores of two groups were lower than those of before nursing,the SDS and SAS scores in the observation group were lower than that in the control group,and the differences were statistically significant(P<0.05).After treatment,the abortion rate in the observation group(38.10%)was lower than that in the control group(52.63%),the clinical pregnancy rate (61.90%)and high quality embryo rate (69.05%)were higher than those in the control group(47.37%,39.47%),and the differences were statistically significant(P<0.05).ConclusionComprehensive nursing intervention can effectively alleviate the psychological pressure of patients with infertility,improve the patients′negative emotions,improve the patients′clinical pregnancy rate and the high quality rate of embryos,change the patients′pregnancy outcome.It is worth applying widely.
2017 Vol. 24 (33): 148-150 [Abstract] ( 147 ) HTML (32 KB)  PDF  (0 KB)  ( 65 )
151 The application effect of gargle disinfection liquid oral care in patients with ventilator associated pneumonia
YE Xiao-ying； ZHENG Xiao-fang； AI Fang-fang ；SHE Ji-lan ；XU Shu-juan； WANG Sheng-li
ObjectiveTo explore the application effect of gargle disinfection liquid oral care in patients with ventilator associated pneumonia(VAP).Methods120 cases of tracheal intubation mechanical ventilation in our hospital from December 2015 to January 2017 were selected as the research object.According to different oral care methods,they were randomly divided into experimental group and control group,60 cases in each group.The control group receivedconventional oral care,the experimental group was given oral care gargle disinfection solution.The incidence of oral diseases in two groups was analyzed.The incidence of VAP in two groups and the results of oral bacterial culture before and after nursing in two groups of patients with VAP were compared.ResultsThe results of the experimental group of patients with oral odor,oral ulcers,oral blood scab incidence was lower than the control group,two groups of patients with halitosis and oral blood scab there was no significant difference between them(P＞0.05);two groups of patients with oral ulcer incidence rate difference was statistically significant(P<0.05).The incidence of VAP in the control group was 30.00%,which was higher than that of 8.33%in the experimental group(P<0.05).After nursing,patients in the experimental group the bacteria strains were significantly lower than the control group,two groups of patients with oral bacterial culture results had significant difference(P<0.05).ConclusionGargle disinfection liquid oral care can reduce the incidence of tracheal intubation in patients with oral disease,reduce the incidence of VAP and improve the oral flora.
2017 Vol. 24 (33): 151-153 [Abstract] ( 173 ) HTML (32 KB)  PDF  (0 KB)  ( 39 )
154 Influence of early nursing intervention on the incidence of related complications in maintenance hemodialysis
QING Zhi-qiang ；GUO Li-ling
ObjectiveTo explore the influence of early nursing intervention on the incidence of related complications in maintenance hemodialysis patients.Methods108 maintenance hemodialysis patients from May 2015 to February 2017 in our hospital were selected as study objects.Patients were divided into observation group and control group according to random number table,and each group was 54 cases.The observation group were treated with early nursing intervention.The control group were treated routine care.The incidence of complications,quality of life and satisfaction of the two groups were observed.ResultsAfter treatment,the incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).The scores of body pain,mental status,emotional function and overall health in the observation group were significantly higher than those in the control group,and the difference was statistically significant(P<0.05).The patient′s satisfaction in the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).ConclusionThere are many kinds of early complications in hemodialysis patients,and mainly of hypertension,heart diseases,infection.Conducting early nursing intervention for patients with maintenance hemodialysis can obviously prevent postoperative complications,reduce the incidence of related complications,improve the life quality of patients,and guarantee and improve the effect of maintenance hemodialysis.
2017 Vol. 24 (33): 154-156 [Abstract] ( 156 ) HTML (31 KB)  PDF  (0 KB)  ( 42 )
157 Application effect of KABP mode in patients with hyperthyroidism
YU Hong-hua
ObjectiveTo study the application effect of knowledge,belief and nursing mode on treatment compliance and negative emotion of patients with hyperthyroidism.MethodsFrom March 2014 to May 2015,80 hyperthyroidism patients in our hospital were treated.They were randomly divided into the control group and the observation group by random number table method.,40 cases in each group.Patients of the control group were given the routine nursing mode;patients in the observation group,on the basis of routine care were used KABP model,Followed up for 1,6 months,1 years,the treatment compliance of the two groups and the negative emotion and sleep quality score of the two groups after 1 year treatment were compared.ResultsThe result of the patients in the observation group took medicine on time,low iodine diet,regular review,after treatment for half a year than the control group (P<0.05).After treatment 1 year,the negative emotion score of the observation group was significantly lower than that of the control group(P<0.05),and the sleeping quality of the observation group was significantly higher than that of the control group,the difference was statistically significant(P<0.05).ConclusionThe nursing mode of knowing and believing can improve the treatment compliance,improve the bad mood,improve the sleeping quality of hyperthyroidism patients..It is worthy of clinical promotion.
2017 Vol. 24 (33): 157-159 [Abstract] ( 143 ) HTML (32 KB)  PDF  (0 KB)  ( 77 )
160 Study on the role of hierarchical nursing in improving postoperative selfcare ability and recovery of patients with ovarian cysts
ZONG Yan； LAI Jun； YANG Gang
ObjectiveTo explore the role of hierarchical nursing to improve postoperative self-care ability and recovery in patients with ovarian cyst.Methods40 patients with ovarian cyst were treated in our hospital from April 2013 to April 2017,they were randomly divided into the control group and the observation group,20 cases in each group.The control group were treated by routine nursing intervention,and the observation group stratified nursing intervention.Comparison of self-care ability of two groups of patients,bed activity time,defecation time,complication rate,exhaust time.ResultsThe scores of defecation,exhaust time,time of bed movement,complication rate,self-care skill score,selfcare ability score,health knowledge level score,self-concept score and self-responsibility score were higher in the observation group than in the control group,the difference was statistically significant(P<0.05).ConclusionThe effect of stratified nursing intervention on ovarian cyst patients was significant.
2017 Vol. 24 (33): 160-161转164 [Abstract] ( 148 ) HTML (31 KB)  PDF  (0 KB)  ( 64 )
162 Application evaluation of holistic nursing model in perioperative nursing care of elderly patients with bone fracture
LI Run-xiang ；JIANG Zhi-li
ObjectiveTo investigate the clinical effect of holistic nursing in perioperative nursing of senile patients with bone injury.MethodsFrom March 2016 to March 2017,142 elderly patients with bone fracture in our hospital were selected as the research object,and they were randomly divided into the control group and the observation group,71 cases in each group.The patients in the control group were treated with routine nursing intervention,while the observation group were treated with holistic nursing intervention.The hospital stay,postoperative complications and satisfaction of the patients were observed and compared between the two groups.ResultsThe incidence of hospital stay and postoperative complications in the observation group were lower than that in the control group,and the satisfaction rate of nursing in the observation group was higher than that in the control group,and the differences was statistically significant(P<0.05).ConclusionIn the perioperative period of senile patients with bone injury in the application of holistic nursing intervention,the effect is significant,can effectively shorten the hospitalization time,reduce the incidence of postoperative complications,improve patient satisfaction with nursing work,worthy of further promotion and application in clinical practice.
2017 Vol. 24 (33): 162-164 [Abstract] ( 172 ) HTML (30 KB)  PDF  (0 KB)  ( 43 )
165 Effect and significance of comfortable nursing in perioperative period of Cesarean section
ZENG YU-lan
ObjectiveTo evaluate the effect and significance of comfortable nursing in perioperative period of Cesarean section.Methods102 cases of Cesarean section who were admitted to our hospital from January 2016 to December were selected.According to the medical record number,the patients were divided into control group and observation group,with 51 cases in each group.The control group was given general care,and the observation group was given comfortable care for perioperative care.The postoperative recovery and postoperative adverse reactions were compared between the two groups of pregnancy women.ResultsBy comparison the postoperative recovery of puerpera in the observation group was higher than that in the control group,and the incidence rate of adverse reactions was lower than that in the control group.The differences were statistically significant(P<0.05).ConclusionPerioperative nursing care for the patients undergoing Cesarean section can promote the postoperative recovery of puerpera and can effectively reduce the incidence rate of postoperative adverse reactions.
2017 Vol. 24 (33): 165-167 [Abstract] ( 149 ) HTML (33 KB)  PDF  (0 KB)  ( 61 )
168 Comparison of the application of whole path green pathway nursing pathway and routine nursing pathway model in emergency children with high fever convulsion
LUO Ai-jun；HU Yu-ying
ObjectiveTo explore the clinical effect of the whole green channel nursing pathway model and routine nursing pathway model in emergency children with high fever convulsion.MethodsSelected 100 cases of children with high fever convulsion in our hospital from February 2014 to December 2016 were randomly divided into the control group and the study group,50 cases in each group.The patients of control group were given routine nursing pathway,and in study group were treated with green corridor nursing pathway.The two groups of patients with stable condition,complications,death,the temperature before and after the first aid,first aid time,fever time,convulsion disappearance time,hospitalization time and nursing satisfaction were compared.ResultsThe proportion of patients in the study group was significantly higher than that in the control group(P<0.05),and the proportion of complications and mortality in the study group was significantly lower than that in the control group(P<0.05).Two groups of patients before emergency temperature showed no significant difference(P＞0.05),first aid research group after body temperature was significantly lower than the control group(P<0.05),the study group hospital time,pyretolysis time,seizures disappeared time and hospitalization time were significantly shorter than the control group(P<0.05).The total satisfaction degree of the patients in the study group(92.00%)was significantly higher than that of the control group(72.00%),the difference was statistically significant(P<0.05).ConclusionThe whole Easy Access nursing pathway in nursing of patients with infantile convulsion in application can effectively alleviate the clinical symptoms,shorten the hospital time,linical symptoms disappeared time and hospitalization time,improve emergency results,improve the quality of nursing and nursing satisfaction.
2017 Vol. 24 (33): 168-170 [Abstract] ( 119 ) HTML (33 KB)  PDF  (0 KB)  ( 43 )
171 Analysis on the effect of integrated Chinese and Western nursing intervention on milk secretion in puerpera undergoing Cesarean section
WANG Min；WANG Xue-hua
ObjectiveTo observe the effect of integrated Chinese and Western nursing intervention on milk secretion in the puerpera undergoing Cesarean section.Methods70 puerpera undergoing Cesarean section in our hospital were selected from March 2016 to January 2017.Based on the principle of even number and odd number grouping,the patients were divided into control group(receiving routine nursing care)and observation group(receiving integrated Chinese and Western nursing intervention),with 35 cases in each group.The lactation start time,milk secretion volume,feeding conditions and the incidence of breast tenderness were compared between the two groups of puerpera undergoing Cesarean section.ResultsThe lactation start time in the observation group was compared with that in the control group,and the start time was significantly earlier.The milk secretion sufficiency rate and breastfeeding rate were significantly higher than those in the control group.The incidence rate of lack of milk secretion,the rate of artificial and mixed feeding,the incidence rate of breast tenderness were compared with those in the control group,which were significantly lower,the difference was statistically significant(P<0.05).ConclusionIntegrated Chinese and Western nursing care can promote postpartum secretion of milk in the puerpera undergoing Cesarean section,which is of high application value and is worthy of further popularization and implementation.
2017 Vol. 24 (33): 171-173 [Abstract] ( 169 ) HTML (31 KB)  PDF  (0 KB)  ( 43 )
174 Comparison of early comprehensive rehabilitation and delayed rehabilitation nursing of complex elbow fractures
CHEN Yu-zhu； ZHANG Su-rong
ObjectiveTo investigate the effect of early comprehensive rehabilitation and delayed rehabilitation nursing after complex elbow fracture.MethodsFrom December 2014 to July 2016,89 patients with complex elbow fractures were selected as the study subjects.According to their date of admission,single day as experimental group,44 cases double day as control group,a total of 45 cases.The former applied to the early comprehensive rehabilitation carethe latter to delay the rehabilitation of care.The elbow joint function,the rehabilitation effect and the elbow ROM score were compared between the two groups before and after rehabilitation.ResultsThe elbow function score and Rom score of the experimental group were higher than those in the control group after intervention,the difference was statistically significant(P<0.05).Before intervention,the difference of the elbow function score and Rom score between the two groups was no significant(P＞0.05).And the excellent rate of treatment in the experimental group was higher than that in the control group，the difference was statistically significant(P<0.05).ConclusionThe early comprehensive rehabilitation of complex elbow fractures is helpful for the recovery of elbow function and the improvement of elbow joint activity.
2017 Vol. 24 (33): 174-176 [Abstract] ( 137 ) HTML (32 KB)  PDF  (0 KB)  ( 31 )
177 Observation on the effect of whole course nursing in emergency treatment of critical patients
HUANG Chong；WU Lian-hong；YANG Yi-hua；XIE Xiao-li
ObjectiveTo explore the effect of whole cours nursing in emergency treatment of emergency patients.MethodsFrom February 2015 to April 2017 in our hospital emergency department admitted to critically ill patients in 180 cases,Review the patient′s care methods were grouped，the control group of 90 patients were given routine care in the rescue group,90 patients on the basis of this group to give full care,The successful rate of rescue,the incidence of adverse events in emergency room,the time spent in opening of venous access,the time of resuscitation room stay and the degree of nursing satisfaction were compared.ResultsThe rescue success rate of the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).The incidence of adverse events was lower in the observation group than in the control group,and the difference was statistically significant(P<0.05).Observation group of patients with successful rescue vein circuit open time-consuming,residence time is shorter than the control group,intensive care and emergency room nurse satisfaction is higher than the control group were treated,the difference was statistically significant(P<0.05).ConclusionThe application of the whole course nursing in the emergency critical care patients can improve the rescue effect,reduce the occurrence of adverse nursing events and save the life of patients,and is worthy of promotion.
2017 Vol. 24 (33): 177-179 [Abstract] ( 157 ) HTML (36 KB)  PDF  (0 KB)  ( 46 )
180 Effect of comprehensive nursing intervention in operation room on stress response of patients
QUAN Neng-hua
ObjectiveTo investigate the effect of comprehensive nursing intervention on surgical stress response in operation room patients.Methods96 operation room patients treated in our hospital from March 2015 to December 2016 were included in the study,and divided into two groups according to different nursing methods,the control group and the observation group,48 cases in each group.The control group receivedroutine nursing intervention,and the observation group received comprehensive nursing intervention.The nursing intervention,stress reaction effect and nursing satisfaction of the two groups were compared and analyzed.ResultsThe two groups of comparison,interview before and before anesthesia compared with control group,SAS and SDS were significantly increased(P<0.05),and the observation group before interview with SAS and SDS before anesthesia score had no significant difference(P＞0.05);comparison between groups,visit the two groups before SAS and SDS score no significant difference(P＞0.05),but before anesthesia in the observation group SAS and SDS scores were significantly lower than the control group (P<0.05),before anesthesia，observe the diastolic blood pressure,systolic blood pressure,heart rate and epinephrine were significantly higher than the control group(P<0.05);after nursing intervention,patients in the observation group on nursing satisfaction (97.92%)was significantly higher than the control group(79.17%),the difference was statistically significant specific(P<0.05).ConclusionGiven the operation room comprehensive nursing intervention on surgical treatment of patients,can effectively reduce the surgical stress response of patients,alleviate the negative emotions of patients and improve patient satisfaction with nursing work,more safety.
2017 Vol. 24 (33): 180-182 [Abstract] ( 158 ) HTML (33 KB)  PDF  (0 KB)  ( 62 )
183 The role of continuous nursing in improving the mental status and reducing complications in patients with thoracolumbar compression fracture
LIANG Fen ；YANG Guo-jun； LIN Jia-we；iLIN Jing； YOU Xiao lian
ObjectiveTo explore the role of continuous nursing in improving the psychological status of patients with thoracolumbar vertebral compression fractures and reducing the incidence of complications.Methods100 patients with thoracolumbar vertebral compression fractures treated in our hospital from February 2014 to December 2016 were divided into two groups according to the random number method,50 cases were treated with routine nursing intervention(control group),50 cases were treated with continuous nursing intervention(study group).The two groups of patients were compared with symptom checklist 90(SCL-90)score,daily living ability score(ADL)and complications.ResultsBefore the intervention,the dimensions of SCL-90 scores between two groups had no significant difference(P＞0.05),stem dimensions prognosis in patients of the study group SCL-90 scores were significantly lower than control group(P＜0.050;before the intervention，the ADL score of the two groups showed no significant difference(P＞0.05),intervention group patients ADL the score was significantly higher than the control group (P＜0.05）,The incidence of complications in the study group(8.00%）)was significantly lower than that in the control group(54.00%)(P＜0.05）.ConclusionIn the thoracic and lumbar compression fractures in patients with continuous nursing care can significantly improve the psychological state of patients,improve the ability of patients with daily life,reduce the risk of complications.
2017 Vol. 24 (33): 183-185 [Abstract] ( 156 ) HTML (33 KB)  PDF  (0 KB)  ( 48 )
186 Value evaluation of nursing intervention in clinical nursing pathway of community acquired pneumonia nursing
SU Min
ObjectiveTo explore the effect of clinical nursing pathway in patients with community acquired pneumonia（CAP）.MethodsFrom June 2013 to December 2014,80 patients with CAP treated in our hospital were selected.They were evenly divided into research group and reference group by computer.The conventional nursing was used in both groups.Besides,the clinical nursing pathway was added in the research group.The hospital stay and clinical outcomes were compared in the two groups.ResultsWith regard to hospital stay,the average hospital stay in the research group was(11.50±11.02)d,better than that in the reference group[(16.20±2.0)d],which was displayed a statistical difference(P<0.05).On the clinical outcomes,the number of improvement,death,and noneffectiveness was 38,0,and 2 in the research group,while in the reference group，they were 34,0,and 6 accordingly,which was not displayed statistical significance(P＞0.05).ConclusionApplication of clinical nursing pathway model in CAPpatients can effectively shorten the hospital stay，improve the quality of life,and reduce medical cost,which is of great importance in clinical research.
2017 Vol. 24 (33): 186-188 [Abstract] ( 153 ) HTML (31 KB)  PDF  (0 KB)  ( 79 )
189 The application detection of expectation treatment in incomplete premature rupture of membranes by special nursing measures
SONG Min
ObjectiveTo approach result of expectation treatment in incomplete premature rupture of membranes by special nursing measures.Methods85 cases clinical data of incomplete premature rupture of membranes patients in our hospital department gynaecology and obstetrics from April 2012 to April 2017 were analyzed，which was divided into two group by different nursing measures，control group（conventional nursing measures） 40 cases and detection group（special nursing measures） 45 cases.The SAS，SDS，prolapse of umbilical cord，fetal distress，oligohydramnion，puerperal infection rate，girth quality，Apgar score of two group premature rupture of membranes patients were detected.ResultsThe SAS，SDS of two group premature rupture of membranes patients were no difference（P＞0.05），the SAS，SDS of control group and detection group after nursing were lower than before nursing，the SAS,SDS of detection group after nursing were lower than control group，the prolapse of umbilical cord，fetal distress，oligohydramnion，puerperal infection rate of detection group premature rupture of membranes patients were lower than control group，the girth quality，Apgar score of detection group premature rupture of membranes patients were higher than control group，the difference were statistical significance(P<0.05).ConclusionThe application of expectation treatment in incomplete premature rupture of membranes by special nursing measures，which could improve adverse psychological conditions，increase pregnancy outcome and neonatal outcome，it is worth to be used.
2017 Vol. 24 (33): 189-191 [Abstract] ( 160 ) HTML (33 KB)  PDF  (0 KB)  ( 70 )
192 Application of orem self-care model and routine care in children with bronchial asthma
ZHU Zi-xin
ObjectiveTo explore the application of Orem self-care model and routine nursing in children with bronchial asthma.MethodsA total of 104 children with bronchial asthma were enrolled in our hospital from October 2015 to April 2016.They were randomly divided into experimental group and reference group according to the random number table method,52 cases in each group.Children with bronchial asthma in the experimental group were treated with Orem self-care model,and the reference group was treated with routine care.After 12 months of treatment,the control of asthma in both groups was compared and the evaluation of their drug compliance and the quality of life were observed.ResultsThe total control rate of asthma in the experimental group was 92.3%,which was significantly higher than that in the reference group(67.3%),the difference was statistically significant(P<0.01).The drug compliance of the experimental group was 96.2%,which was significantly higher than that of the reference group(71.2%),the difference was statistically significant(P<0.01).There was no significant difference in the quality of life between the experimental group and the reference group before the intervention (P>0.05).After intervention,the activity dimension,emotional dimension and symptom dimension of the experimental group were higher than those of the reference group,the differences were statistically significant(P<0.05).ConclusionOrem self-care in children with bronchial asthma care model can effectively reduce the recurrence rate of asthma,improve asthma control rate,improve patient compliance and quality of life of drugs.
2017 Vol. 24 (33): 192-194 [Abstract] ( 187 ) HTML (34 KB)  PDF  (0 KB)  ( 72 )
195 Application of nursing intervention in patients with renal failure treated by blood purification
LI Zheng
ObjectiveTo investigate the effect of nursing intervention in patients with renal failure treated by blood purification.MethodsFrom March 2015 to August 2016,88 patients with renal failure treated by blood purification in our hospital were selected as research objects.According to admission time,they were divided into intervention group(45 cases)and control group (43 cases).In the control group,traditional care was used,while in the experimental group,nursing intervention was adopted.The anxiety,depression score,the effective rate of skin itch remission and satisfaction were compared in the two groups.ResultsBefore intervention,depression and anxiety scores were compared in both groups,and the differences were not statistically significant(P>0.05).After the intervention,the depression scores of patients in the experimental group [(38.59±3.23)points]and the anxiety score [(41.13±3.19)points]were superior to the control group[(47.48±4.21),(51.27±0.21)points],and the differences were statistically significant(P<0.05).The effective rate of skin itch remission in the experimental group(95.56%)and satisfaction rate(93.33%)were higher than those in the control group(72.09%,67.44%),and the differences were statistically significant(P<0.05).ConclusionEffective nursing intervention improves patient′s therapeutic effect as well as mental state,which is beneficial to better the nurse-patient relationship and improve the satisfaction.
2017 Vol. 24 (33): 195-197 [Abstract] ( 150 ) HTML (33 KB)  PDF  (0 KB)  ( 73 )
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