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| Clinical effect comparison of Desogestrel and Ethlinylestradiol Tablets and Medroxyprogesterone in the treatment of adolescent dysfunctional uterine bleeding |
| LIU Zhi-hua |
| Department of Gynaecology,Xiniujiao Community Health Service Station,Jingxi Street,Baiyun Districtin Guangzhou City of Guangdong Province,Guangzhou 510515,China |
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Abstract ObjectiveTo compare the clinical effect of Desogestrel and Ethlinylestradiol Tablets and Medroxyprogesterone in the treatment of adolescent dysfunctional uterine bleeding in order to provide a scientific basis for the drug choice of clinical treatment.MethodsFrom March 2015 to March 2017,52 patients with adolescent dysfunctional uterine bleeding treated by Medroxyprogesterone in our hospital were selected into control group.Meanwhile,52 patients with adolescent dysfunctional uterine bleeding treated by Desogestrel and Ethlinylestradiol Tablets in our hospital were classified into observation group.The clinical effect by the two different methods was compared.ResultsThe total effectiveness rate was 98.0%in the observation group,much higher than that in the control group accounting for 82.7%(χ2=6.172,P<0.05).Compared with the control group,the improvement of endometrial thickness,menstrual cycle,volume of menses after therapy was all more remarkable(t=3.168,t=32.413,t=11.607;P<0.05).The incidence of adverse reactions in the observation group was 9.6%,much lower than that in the control group accounting for 32.7%(χ2=17.146，P<0.05).ConclusionFor adolescent dysfunctional uterine bleeding,both Desogestrel and Ethlinylestradiol Tablets and Medroxyprogesterone can obtain a certain effect,and is better in the former which has a lower incidence of adverse reactions and a more reliable safety in clinical application after comparison.Desogestrel and Ethlinylestradiol tablets is worthy to be widely promoted in clinical application.
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