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Quick Search     Adv Search 2020 Vol. 27, No. 18 Published: 2020-06-28   4 Meta-analysis of Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection combined with Low Molecular Weight Heparin in preventing lower extremity deep venous thrombosis associated with orthopedic diseases ZHANG Chao-ming; LIN Tian-ye2; YANG Peng; XU Jing-li; XIONG Bing-lang; ZOU Qi-zhao; LAI Qi-zhong; ZHANG Qing-wen Objective To systematically evaluate the effect and safety of Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection combined with Low Molecular Weight Heparin in preventing lower extremity deep venous thrombosis associated with orthopedic diseases. Methods The randomized controlled clinical trials were retrieved related to Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection combined with Low Molecular Weight Heparin (combination group) versus Low Molecular Weight Heparin (control group) used to prevent orthopedic related diseases in the prevention of lower limb deep vein thrombosis by computer in China Biology Medicine (CBM)，China National Knowledge Internet (CNKI)，VIP database (VIP)，Wanfang database，PubMed，Embase，Cochrane Library，Web of Science and other databases. The time was from the establishment of the database to November 2019. Documents were selected according to the inclusion and exclusion criteria，the methodological quality of the included studies was strictly evaluated and data were extracted，and Meta analysis was performed using RevMan 5.3. Results A total of 955 patients were enrolled in 11 studies. Meta analysis results showed that the incidence of deep vein thrombosis，Ddimer，and plasma activated partial thrombin time after treatment in the combination group were better than those in the control group，and the differences were statistically significant (P＜0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups (P＞0.05). Conclusion The application of Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection combined with Low Molecular Weight Heparin can effectively improve the blood hypercoagulability and prevent the incidence of deep vein thrombosis，and it is safe and does not increase the adverse reactions，which is worth clinical promotion. 2020 Vol. 27 (18): 4-8 [Abstract] ( 84 ) HTML (44 KB)  PDF  (0 KB)  ( 9 ) 9 Clinical analysis of 4 cases of children with global developmental delay and characteristic electroencephalogram pattern WAN Rui-ping; WU Ben-ze; LIU Zhi-gang; DONG Shi-wei; HUANG Xiao-fei Objective To analyze the clinical characteristics and etiology of children with comprehensive developmental delay and characteristic EEG abnormalities. Methods From January 2018 to September 2019，4 cases of children with developmental retardation/mental disability were diagnosed by video EEG examination in the Department of Pediatric Rehabilitation，Foshan Maternal and Child Health Hospital Affiliated to Southern Medical University. The characteristics were retrospectively analyzed，and the results of auxiliary examinations such as Gesell Development Diagnostic Scale and genetic examination were summarized and analyzed. Results The children′s age at the first diagnosis was 6-21 months，and there were no definite abnormalities in the birth history and family history. All children were diagnosed with ＂developmental backwardness＂ as the first reason. Gesell′s Developmental Diagnostic Scale showed that there were various degrees of developmental delay in each energy zone. Three children had hypopigmentation of the skin，and 2 cases had frequent laughter and hyperactivity，and neither had epilepsy or febrile seizures. All children′s electroencephalograms had characteristic manifestations. Among them，3 cases mainly showed that the front head was markedly rhythmic high-very high amplitude delta wave burst or continuous distribution，with posterior head rhythmic spike slow wave distribution. One case mainly exhibited extensive high-amplitude 4-6 Hz θ activity. Methylation-specific multiple ligation-dependent probe amplification detection results showed that 3 children had 15q11-13 maternal fragments missing，1 patient had 15q11-13 paternal diploid，and finally diagnosed Angelman syndrome. Conclusion The early clinical manifestations of children with Angelman syndrome lack specificity or are easily overlooked. For children with unexplained stunting/mental disability，even if there is no convulsions，routine EEG examination is recommended. The EEG of children with Angelman syndrome has certain characteristics，which can provide clues for early diagnosis and guide further genetic examination to confirm the diagnosis. 2020 Vol. 27 (18): 9-12 [Abstract] ( 94 ) HTML (37 KB)  PDF  (0 KB)  ( 12 ) 13 Effect comparison of Oxycodone and Butorphanol in preventing Sufentanil-induced cough CAO Lin; LI Mou; HUANG Xiao-ling Objective To investigate the effect of Oxycodone and Butorphanol in preventing Sufentanil-induced cough.Methods A total of 120 patients (aged 18-60 years，American Association of Anesthesiologists ［ASA］ Ⅰ-Ⅱ) undergoing elective surgery for general anesthesia intubation in our hospital from September 2018 to October 2019 were selected as the research subjects. They were divided into group O，group B and group S according to the random number table method，40 cases in each group. Patients in group O received intravenous injection of 0.05 mg/kg Oxycodone，patients in group B received intravenous injection of 0.01 mg/kg Butorphanol，and patients in group S received intravenous equivalent volume of 0.9% normal saline. Sufentanil 0.4 μg/kg was injected 30 seconds later and administrated within 5 seconds. Other anesthesia drugs were given 1 minute later for induction and endotracheal intubation. The severity and incidence of cough during anesthesia induction，as well as the average arterial pressure (MAP) and heart rate (HR) before anesthesia induction (T0)，before the injection of Sufentanil (T1)，2 minutes after endotracheal intubation (T2) were observed and recorded. Results The total incidence rate of cough in group S was 35.0% (14/40，mild 4 cases，moderate 7 cases，and severe 3 cases)，group O was 10.0% (4/40，mild 3 cases，moderate 1 case)，and group B was 12.5% (5/40，mild 5 cases). The total incidence rate and severity of cough of patients in group O and B were lower than those in group S，and the differences were statistically significant (P＜0.05). There were no significant differences in the total incidence rate and severity of cough between group O and group B (P＞0.05). At T0，T1 and T2，there were no significant differences in MAP and HR among the three groups (P＞0.05). Conclusion Oxycodone at 0.05 mg/kg and Butorphanol at 0.01 mg/kg can safely and effectively prevent Sufentanil-induced cough with similar effect. 2020 Vol. 27 (18): 13-16 [Abstract] ( 108 ) HTML (43 KB)  PDF  (0 KB)  ( 13 ) 17 Study on the preparation process of Fat Reduction and Lightweight Body Cream HU Zhong-sheng； HE E-ying； ZHOU Gang； ZHANG Li-ping Objective To optimize the best preparation process of Fat Reduction and Lightweight Body Cream. Methods According to the prescription characteristics of the Fat Reduction and Lightweight Body Cream，with the rate of cream production as the index，a combination of single-factor experiment and orthogonal test were adopted. The investigation factors such as immersion time，amount of water added，extraction temperature，and extraction time were selected for selection of optimal preparation conditions for the Fat Reduction and Lightweight Body Cream. Results The optimal process conditions for the preferred Fat Reduction and Lightweight Body Cream were immersion time 50 minutes，1000 ml of water added，and extraction performed twice at 100°C under normal pressure for 180 minutes each time. After standing，re-precipitation and filtration were combined，the less medicine residue，the better preparation process. Conclusion The preparation process is reasonable and feasible，and it complies with the requirements of Specification for Quality Management of Pharmaceutical Production and has a high rate of cream production. 2020 Vol. 27 (18): 17-20转24 [Abstract] ( 92 ) HTML (44 KB)  PDF  (0 KB)  ( 12 ) 21 Current status and prospect of pharmacotherapy for allergic rhinitis CHENG Pan-feng； ZHANG Shan-hua； QIU Xiao-hua； HOU Rong； ZHU Chong-mei； CHENG Ru-bin Allergic rhinitis (AR) is a chronic respiratory disease mediated by IgE，and it is also a common global respiratory multiple disease. It has the characteristics of high incidence，high recurrence rate and difficult to cure，which has a serious impact on the quality of life of patients，so the search for effective anti-AR drugs has become the focus of medical research. With the in-depth study of the pathogenesis of AR，Western medicine therapy represented by antihistamines and hormone drugs，targeted drugs represented by anti-IgE monoclonal antibody，and immunotherapy represented by lymphatic immunotherapy and epidermal immunotherapy continue to emerge，and some drugs have achieved gratifying results. In addition，traditional Chinese medicine，as a substitute and supplement，has shown a good application prospect in the treatment of AR. This paper summarizes the current situation of drug treatment of AR，combs the shortcomings of existing therapeutic drugs，and looks forward to the possible breakthrough direction of treatment in the future，in order to provide new ideas and reference for follow-up drug development. 2020 Vol. 27 (18): 21-24 [Abstract] ( 84 ) HTML (39 KB)  PDF  (0 KB)  ( 13 ) 25 Research progress of Chinese medicine treating depression ZHANG Hao-yi； ZHANG He-ming At present，depression has become a kind of mental illness that can not be ignored，which seriously endangers human physical and mental health. Antidepressant has been widely used in the clinic which are mostly chemically synthesized，with disadvantages of large side effects，slow onset，and poor efficacy. Traditional Chinese medicine has unique experience in treating depression and other psychiatric diseases，so it is possible to develop antidepressants with good efficacy and small side effects. Based on recent researches on different antidepressant Chinese medicine，this paper focuses on the mechanism of antidepressant Chinese medicine both in clinical and animal experiments，summarizes the antidepressant mechanism of single and compound Chinese medicine，so as to provide the necessary theoretical basis for Chinese medicine in clinical treatment and basic research. 2020 Vol. 27 (18): 25-29 [Abstract] ( 104 ) HTML (52 KB)  PDF  (0 KB)  ( 13 ) 30 Advances in the study, diagnosis and treatment of vitamin B12 in tumor,obesity and diabetes mellitus 12 in tumor,obesity and diabetes mellitus[J]. 中国当代医药, 2020,27(18): 30-33转41')" href="#"> LUO Feng-yong； CHEN Shuai； ZHOU Yan； YANG Hao-jun； TANG Li-ming In recent years，with the in-depth study of tumors，obesity and diabetes，more and more drugs and substances in the human body have been found to play a role in the occurrence and progression of these diseases，and vitamin B12 is one of the hot researches. Epidemiological investigations and case-control studies have revealed that vitamin B12 is inextricably linked to the occurrence and development of tumors，obesity and diabetes in the human body.The relevant treatment methods for tumors，obesity and diabetes can reduce the level of vitamin B12 in patients，while the deficiency of B12 can also lead to the occurrence and development of tumors，obesity and diabetes，and the deficiency of vitamin B12 has caused a series of diseases. A large number of studies have provided clues for the follow-up indepth research by exploring the mechanism of action of vitamin B12. 2020 Vol. 27 (18): 30-33转41 [Abstract] ( 104 ) HTML (60 KB)  PDF  (0 KB)  ( 8 ) 34 Application effect of Compound Danshen Injection in acute ST-segment elevation myocardial infarction patients with percutaneous coronary intervention CHEN Dong-lang； ZOU Pei-yuan； LU Yong-zhao Objective To observe the application effect of Compound Danshen Injection in patients with acute ST segment elevation myocardial infarction (STEMI) after percutaneous coronary intervention (PCI). Methods A total of 60 acute STEMI patients who underwent PCI from January 2018 to June 2019 were selected as the research objects，and they were divided into the experimental group and the control group according to the mothod of random control，30 cases in the each group. Both groups were given routine clinical treatment，on this basis，the experimental group was given Compound Danshen Injection. Renal function indexes，including serum creatinine (SCr)，estimated glomerular filtration rate (eGFR)，the incidence of contrast nephropathy (CIAKI) were compared and analyzed between the two groups before surgery and after surgery at 3 days. Coronary blood flow grading (TIMI grading)，cardiac function indexes，including ventricular ejection fraction (LVEF)，left ventricular end-diastolic diameter (LVEDD) and left ventricular end-systolic diameter (LVESD)，each index of cardiac (SVI)，NT-pro BNP were analyzed and compared between the two groups after 7 days of the treatment. Results After treatment，the level of SCr of the experimental group was lower than that of the control group，the level of eGFR of the experimental group was higher than that of the control group，and the incidence of CIAKI of the experimental group was lower than that of the control group，the differences were statistically significant (P＜0.05). The TIMI grading of coronary blood flow in the experimental group was better than that in the control group，the differences was statistically significant (P＜0.05). Cardiac function indexes were improved in both groups，but the LVEF and SVI in the experimental group were higher than those in the control group，while LVEDD and LVESD in the experimental group were lower than those in the control group，the differences were statistically significant (P＜0.05). The indexes of NT-pro BNP in the experimental group was lower than that in the control group，the differences was statistically significant (P＜0.05). Conclusion In the treatment of acute STEMI after PCI，Compound Danshen Injection can reduce CIAKI，protect renal function and improve cardiac function. 2020 Vol. 27 (18): 34-37 [Abstract] ( 84 ) HTML (40 KB)  PDF  (0 KB)  ( 9 ) 38 Clinical study of coronary intravascular ultrasound imaging guide in the interventional therapy of severe calcification lesion SU Yong-cai； ZHANG Xiao-le； DENG Bin； SU Liang-xian Objective To study the effectiveness and safety of coronary intravascular ultrasound (IVUS) imaging guide in the interventional therapy of severe calcification. Methods From January 2016 to January 2019，99 patients with severe calcification treated in our hospital and requiring coronary intervention were selected as the research objects，and they were divided into the coronary IVUS imaging group (the IVUS group，46 cases) and the routine coronary intervention group (the routine group，53 cases) according to whether to use IVUS during coronary intervention. IVUS was used in the IVUS group，IVUS was not used in the routine group. The success rate of stent implantation，the incidence of complications during operation and hospitalization after operation，and the follow-up results of major adverse cardiac events during hospitalization and after operation at one year were observed and compared between the two groups. Results The success rate of stent implantation in the IVUS group was higher than that in the routine group，and the difference was statistically significant (P＜0.05). There was no significant difference between the two groups in the incidence of complications during operation and hospitalization after operation (P＞0.05). The follow-up results showed that the incidence of central colic and heart failure in the IVUS group after operation at one year were significantly lower than those in the routine group，and the differences were statistically significant (P＜0.05). Conclusion IVUS can improve the success rate of stent implantation and reduce the incidence of major clinical adverse cardiac events one year after operation，which has clinical significance in the interventional treatment of severe calcification of coronary artery. 2020 Vol. 27 (18): 38-41 [Abstract] ( 75 ) HTML (34 KB)  PDF  (0 KB)  ( 11 ) 42 Clinical effect comparison of laparoscopic radiofrequency ablation and laparoscopic hepatectomy in the treatment of chronic hepatitis B virus related special location small primary liver cancer DAI Wei; MO Cong; SHA Rong-gui; DAI Jia-liang; CAI Guan-he; MIAO Hui-lai; BAO Shi-ting; CHEN Ming; TAN Xiao-yu; LI Ming-yi; CHEN Nian-ping Objective To evaluate the effect and safety of laparoscopic radiofrequency ablation (LRFA) and laparoscopic hepatectomy (LH) in the treatment of chronic hepatitis B virus related special location primary liver cancer. Methods A retrospective analysis of 97 patients with chronic hepatitis B-related special site HCC patients admitted to the Affiliated Hospital of Guangdong Medical University from January 2012 to December 2017 was made，a total of 116 nodules. According to different treatment methods，they were divided into two groups. LRFA group (45 cases) received LRFA treatment，LH group (52 cases) received LH method，and were followed up for 2 years after surgery. The overall survival rate，postoperativ，liver function changes，hospital stay and incidence of complications were compared between two groups. Results The complete ablation rate of tumors in the LRFA group was 100%. The 1- and 2-year overall survival rates in the LRFA group were 90.7% and 84.0%，and those in the LH group were 91.4% and 82.5%. There was no significant difference between the two groups (P＞0.05). The level of alanine aminotransferase after LRFA was lower than that of LH group，the difference was statistically significant (P＜0.05). The hospital stay in the LRFA group was shorter than that in the LH group，and the difference was statistically significant (P＜0.05). The incidence of complications between the two groups was not statistically significant (P＞0.05).Conclusion For chronic hepatitis B virus related special location small primary liver cancer，both LRFA and LH are effective. However，LRFA not only has less liver function damage and fewer complications，but also broadens the scope of application of radiofrequency ablation，which is more advantageous for treating special location liver cancer. 2020 Vol. 27 (18): 42-45 [Abstract] ( 86 ) HTML (37 KB)  PDF  (0 KB)  ( 6 ) 46 Clinical effect comparison of early enteral nutrition and parenteral nutrition in the treatment of patients with mechanical ventilation in the intensive care unit ZHAN Zhi-Fang; CUI XI-jun Objective To explore the clinical effect of early enteral nutrition （EN) and parenteral nutrition (PN) in patients with mechanical ventilation in intensive care unit (ICU). Methods A retrospective analysis of 86 mechanically ventilated patients admitted to the ICU from January 2015 to October 2019 was made. Within 48 hours after admission，the patients who received enteral nutrition were performed in EN group (56 cases)，those who received parenteral nutrition (30 cases) were performed in PN group，at the same time they were given conventional treatment. After entering the ICU and after 7 days of treatment，the triceps skin fold thickness (TSF) and upper arm muscle circumference (AMC)，hemoglobin (Hb)，blood C-reactive protein (CRP)，albumin (ALB)，gluten alanine aminotransferase (ALT) levels were compared. The time of mechanical ventilation，ICU hospital stay，the presence or absence of ventilator-associated pneumonia (VAP) and gastrointestinal bleeding were compared between the two groups. Results After 7 days of nutritional support treatment in the EN group，Hb was slightly higher than that before treatment，the difference was not statistically significant (P＞0.05)； ALB was higher than that before treatment，the difference was statistically significant (P＜0.05).After nutritional support in the PN group，Hb was lower than that before treatment，the difference was statistically significant (P＜0.05)； while ALB compared with nutritional treatment，the difference was not statistically significant (P＞0.05)； after treatment between the two groups，only Hb and ALB in EN group were higher than those in PN group，the difference was statistically significant (P＜0.05). The mechanical ventilation time and ICU hospital stay in the PN group were longer than those in the EN group，and the difference was statistically significant (P＜0.05)； the 2-week success rate of withdrawal in the EN group was higher than that in the PN group，and the difference was statistically significant (P＜0.05). In the EN group ，the incidence of VAP，the incidence of gastrointestinal hemorrhage，and the 28-day mortality were lower than those of the PN group，but the difference was not statistically significant (P＞0.05). Conclusion The early metabolic effect of EN in patients with mechanical ventilation is better and more in line with the physiological state，which can improve the success rate of withdrawal，shorten the time of mechanical ventilation，reduce complications，and thus improve the prognosis and shorten the hospital stay. 2020 Vol. 27 (18): 46-49 [Abstract] ( 72 ) HTML (35 KB)  PDF  (0 KB)  ( 12 ) 50 Clinical application study of precise anatomical retroperitoneal laparoscopic technique in adrenal tumorectomy WANG Su-gui; LI Qiang; WU Zi-yu; JIANG Fu-jin; ZHANG Xian-yun Objective To explore the clinical application value of precise anatomical retroperitoneal laparoscopic technique in adrenal tumorectomy. Methods From January 2016 to June 2019，40 patients with adrenal tumor from the Urology Department of Huai′an Hospital Affiliated to Xuzhou Medical College were selected. They were divided into the experimental group and the control group according to a random number table method，20 cases in each group. In the experimental group，the precise anatomical retroperitoneal laparoscopic technique was used for accurate separation of non vascular layer and adrenalectomy. In the control group，adrenal tumorectomy with traditional retroperitoneal laparoscopic technique was given. The operative time，intraoperative bleeding volume，operative complications，postoperative drainage tube retention time and postoperative hospital stay time were compared between the two groups. Results The operation time of the experimental group was significantly shorter than that of the control group，and the intraoperative bleeding of the experimental group was significantly less than that of the control group，the difference was statistically significant (P＜0.05). There was no significant difference between the two groups in the incidence of postoperative complications，the postoperative drainage tube retention time and the postoperative hospital stay time (P＞0.05). Conclusion Precise anatomical retroperitoneal laparoscopic technique in adrenal tumorectomy is safe，reliable，effective and minimally invasive，which is worth popularizing in clinic. 2020 Vol. 27 (18): 50-52 [Abstract] ( 75 ) HTML (32 KB)  PDF  (0 KB)  ( 13 ) 53 Application of knowledge attitude belief practice nursing mode in patients with kidney stones treated by flexible ureteroscope ZOU Xue-zhen  Objective To explore the application effect of knowledge attitude belief practice (KABP) nursing mode in patients with kidney stones treated by flexible ureteroscope. Methods A total of 80 patients with kidney stones treated in our hospital from September 2018 to September 2019 were selected as the research subjects. They were divided into the control group (n=40) and the observation group (n=40) by drawing lottery. In the control group，conventional nursing was used，and in the observation group，KABP nursing mode was adopted. The disease awareness，compliance score，self-care ability，quality of life index (QLI)，nursing outcome (NOC)，postoperative complications，and overall nursing satisfaction rate were compared between the two groups. Results In the observation group，the disease awareness，compliance with doctor′s advice，self-care ability，NOC score，QLI score，and total nursing satisfaction rate were all higher than those in the control group，and the differences were statistically significant (P＜0.05). The total incidence of complications in the observation group was lower than that of the control group，and the difference was statistically significant(P＜0.05). Conclusion The use of the KABP nursing mode in patients with kidney stones treated by flexible ureteroscope can strengthen the disease cognitive awareness，self-care ability and compliance with doctor′s advice，reduce the incidence of postoperative complications，improve their quality of life and nursing satisfaction，which is worthy of clinical application. 2020 Vol. 27 (18): 53-55 [Abstract] ( 77 ) HTML (32 KB)  PDF  (0 KB)  ( 11 ) 56 Clinical effect of Aricept combined with Mecobalamin in the treatment of vascular dementia LIU Na； LI Xue-fei Objective To investigate the effect of Aricept combined with Mecobalamin in the treatment of vascular dementia. Methods A total of 80 patients of vascular dementia admitted to the First People′s Hospital of Zhenjiang City from January to December in 2018 were selected and divided into the combinated group (40 cases) and the control group (40 cases) according to the randomized control method. Patients in the combinated group were given Aricept combined with Mecobalamin，while patients in the control group were only given Aricept. The cognitive ability of the two groups before and after treatment was compared，evaluated by mini mental state examination (MMSE) and Montreal Cognitive Assessment (MoCA)，at the same time，the adverse reactions of the two groups were observed. Results There were no significant differences in the MMSE，MoCA scores between the two groups before treatment (P＞0.05). The MMSE，MoCA scores of the two groups after treatment were higher than those before treatment，the difference were statistically significant (P＜0.05). The MMSE，MoCA scores of the combined group were higher than those of the control group，the difference were statistically significant (P＜0.05). Compared with the control group，there was no significant increase in adverse reactions in the combined group，without significant difference (P＞0.05). Conclusion Aricept combined with Mecobalamin can improve the cognitive function and daily living ability of vascular dementia patients，the clinical effect is accurate and safe，which is better than that of Aricept alone. 2020 Vol. 27 (18): 56-58转62 [Abstract] ( 95 ) HTML (35 KB)  PDF  (0 KB)  ( 8 ) 59 Effect of improved method for measuring the length of gastric tube indwelling on the monitoring of gastric residue in patients with stroke TIAN He; ZHANG Lu Objective To study the effect of improved method for measuring the length of gastric tube indwelling on the monitoring of gastric residue in patients with stroke. Methods The clinical data of 100 patients with stroke admitted to our hospital from May 2017 to May 2019 who underwent enteral nutrition through nasogastric tube were retrospectively analyzed. According to the different length of gastric tube indwelling，the patients were divided into control group and experimental group，with 50 patients in each group. The control group used the traditional method to measure the length of gastric tube indwelling，and the experimental group used the modified method to measure the length of gastric tube indwelling. The lengths of indwelling gastric tube in each height segment (height＜160，160-170 and ＞170 cm)were compared between the two groups of patients. The incidence rates of reflux，cough and aspiration were compared between the two groups. Gastric residue monitoring was compared between the two groups. Results The lengths of indwelling gastric tube in the experimental group of patients in each height segment were longer than those in the control group，and the differences were statistically significant (P＜0.05). The incidence rates of aspiration，cough and reflux in the experimental group were lower than those in the control group，with statistically significant differences (P＜0.05). The gastric residual amount on the 9th，and 10th days of the experimental group were lower than those on the 2nd day，and the gastric residual amount on the 2nd，3rd，9th，and 10th days of the experimental group were higher than those in the control group，with statistically significant differences (P＜0.05). Conclusion The improved method for measuring the length of indwelling gastric tube can accurately detect the residual amount in the stomach and reduce the incidence of aspiration，cough and reflux. 2020 Vol. 27 (18): 59-62 [Abstract] ( 65 ) HTML (36 KB)  PDF  (0 KB)  ( 9 ) 63 Application of repetitive transcranial magnetic stimulation combined with Paroxetine Hydrochloride in patients with post-stroke depression HU Mei; LI Man-lian; CHEN Yu-qian; YI Lin; ZOU Yun-feng; JIANG Li-li Objective To investigate the clinical effect of repetitive transcranial magnetic stimulation combined with Paroxetine Hydrochloride in the treatment of post-stroke depression. Methods A total of 80 patients with post-stroke depression treated in our hospital from April 2016 to April 2019 were selected as the research objects，and they were divided into the control group (40 cases) and the observation group (40 cases) according to the blind selection grouping method. The control group was treated with Paroxetine Hydrochloride. The observation group was treated with Paroxetine Hydrochloride combined with repeated transcranial magnetic stimulation. Depression scores and serum-related indexes were compared between the two groups before and after treatment. Results There were no significant difference in the scores of Hamilton depression scale (HAMD) and Montgomery depression scale (MARDS) before treatment between the two groups (P＞0.05). After treatment，the scores of HAMD and MARDS in the observation group were lower than those in the control group，the difference were statistically significant (P＜0.05). There were no significant difference in the levels of serum brain-derived neurotrophic factor (BDNF)，neuropeptide Y (NPY) and adrenocorticotropic hormone releasing factor (CRF) between the two groups before treatment (P＞0.05). After treatment，the levels of serum BDNF and NPY in the observation group were higher than those in the control group，and the CRF level in the observation group was lower than that in the control group，and the difference were statistically significant (P＜0.05). Conclusion Repetitive transcranial magnetic stimulation combined with Paroxetine Hydrochloride in treating post-stroke depression is more effective，it can significantly alleviate the depression of patients and significantly improve the level of nerve function in the body，which is worthy of promotion and application. 2020 Vol. 27 (18): 63-65 [Abstract] ( 71 ) HTML (31 KB)  PDF  (0 KB)  ( 12 ) 66 Clinical effect of Nimodipine Injection combined with Betahistine Sodium Chloride Injection in the treatment of posterior circulation ischemia LIU Shi-wu; CHEN Cui-yun; GU Zhi-ying; LU Zhan-hong Objective To investigate the clinical effect of Nimodipine Injection combined with Betahistine Sodium Chloride Injection in the treatment of posterior circulation ischemia. Methods One hundred patients with posterior circulation ischemia who were admitted to our hospital from January 2018 to September 2019 were selected as subjects of this study. They were divided into control group and study group by random number table method，with 50 cases in each group. The control group was treated with Betahistine Sodium Chloride Injection alone. The study group was treated with Nimodipine Injection combined with Betahistine Sodium Chloride Injection. The therapeutic effect，hemodynamics，blood lipid，hemorheology and fibrinogen of the two groups were compared. Results The total clinical effective rate was 82.0% in the control group and 94.0% in the study group. The total clinical effective rate of the study group was higher than that of the control group，and the difference was statistically significant (P＜0.05). The improvement time of the symptoms of the patients in the control group was (9.34±2.76) d，and the improvement time of the symptoms of the patients in the study group was (5.23±2.11) d. The improvement time of the patients in the study group was shorter than that in the control group，and the difference was statistically significant (P＜0.05). The average blood flow velocities of the left vertebral artery (left VA)，right vertebral artery (right VA) and basilar artery (BA) of the patients in the study group after treatment were higher than those before treatment，and the differences were statistically significant (P＜0.05). The average blood flow velocities of left VA，right VA and BA after treatment in the control group were not statistically significant compared with those before treatment (P＞0.05). The average blood flow velocities of left VA，right VA and BA in the study group after treatment were higher than those in the control group，and the differences were statistically significant (P＜0.05). Plasma viscosity，fibrinogen，platelet aggregation rate，triglyceride (TG)，total lipoprotein (TC) and low density lipoprotein cholesterol (LDL-C) of the two groups after treatment were all lower than those before treatment，and the differences were statistically significant (P＜0.05). The high density lipoprotein cholesterol (HDL-C) levels after treatment in the two groups were higher than those before treatment，and the differences were statistically significant (P＜0.05). The plasma viscosity，fibrinogen，platelet aggregation，TG，TC and LDL-C of patients in the study group after treatment were all lower than those in the control group，and the differences were statistically significant (P＜0.05). The HDL-C of the study group after treatment was higher than that of the control group，and the difference was statistically significant (P＜0.05). Conclusion Nimodipine Injection combined with Betahistine Sodium Chloride Injection has a good clinical effect in the treatment of posterior circulation ischemia，which can improve hemodynamics and fibrinogen. It is worthy of clinical promotion and reference. 2020 Vol. 27 (18): 66-69 [Abstract] ( 79 ) HTML (37 KB)  PDF  (0 KB)  ( 10 ) 70 Effect comparison of Kugel and TAPP in the treatment of adults inguinal hernia TAO Hong-fa； XIAO Yong； ZHAO Kun Objective To compare the clinic effect of modified-Kugel and transabdominal preperitoneal repair (TAPP)in the treatment of adults inguinal hernia. Methods The clinical data of 173 patients with inguinal hernia treated in our hospital from January 2015 to March 2017 were retrospectively analyzed. Patients were divided into modified-Kugel group (78 cases) and the TAPP group (95 cases). The differences in surgical indicators (diameter of hernia sac，operation time，visual analogue scale ［VAS］)，postoperative complications (pain degree，hematoma，effusion，foreign body sensation) and recurrence after 2 years were compared between the two groups. Results There were no significant differences in the diameter of hernia sac neck，operation time and VAS score between the two groups (P＞0.05). There were no significant difference in the incidence rates of early pain，chronic pain and postoperative complications between the two groups (P＞0.05). After 2 years follow-up，there was no significant difference in recurrence rate between the two groups (P＞0.05). Conclusion Modified- Kugel repair and TAPP repair have the same effect treating adult inguinal hernia. Treatment can be selected according to the indication and the specific situation of the patient. 2020 Vol. 27 (18): 70-72转76 [Abstract] ( 64 ) HTML (33 KB)  PDF  (0 KB)  ( 8 ) 73 Effect comparison of traditional laparotomy and laparoscopic modified rectorectomy in the treatment of rectal prolapse CHEN Yong-qiang Objective To compare the effects of traditional laparotomy and laparoscopic modified anterior rectal resection on in the treatment of rectal prolapse. Methods A total of 30 cases of rectal prolapse patients admitted to our hospital from June 2017 to June 2019 were selected as the research objects，and were divided into the control group (n=15) and the study group (n=15) according to the computer equivalent random method. The control group was treated with traditional open surgery，while the study group was treated with laparoscopic modified rectal resection. The operative indexes and postoperative complications of the two groups were compared. Results The operation time of the study group (［103.5±2.1］ min) and postoperative hospital stay (［6.5±1.2］ d) were shorter than those of the control group(［154.6±2.5］ min，［13.4±2.5］ d)，intraoperative blood loss (［80.3±16.9］ ml) was less than that of the control group(［115.4±17.5］ ml)，and the total incidence of postoperative complications (13.33%) was lower than that of the control group (53.33%)，with statistically significant differences (P＜0.05). Conclusion In the treatment of rectal prolapsed，laparoscopic modified rectocelectomy can effectively reduce the amount of bleeding，accelerate the recovery time，reduce the incidence of complications，and improve the quality of life，which has a certain clinical application value. 2020 Vol. 27 (18): 73-76 [Abstract] ( 75 ) HTML (33 KB)  PDF  (0 KB)  ( 12 ) 77 Application effect comparison of two suture methods in thoracoscopic lobectomy DING Yi-lin； ZHAO Qiang； ZHAO Xiao； HU De-hong Objective To compare the application effect of two suture methods in thoracoscopic lobectomy. Methods The clinical data of 200 patients undergoing thoracoscopic lobectomy who were admitted and treated in Weifang People′s Hospital from July to November 2019 were retrospectively analyzed. According to different suture methods，the patients were divided into control group (n=100) and study group (n=100). The control group was treated with a traditional suture method while the study group was subjected to intradermal suture with 4-0 Prolene. The speed of incision suture，the suture time，scar area，pain score on the 3rd day after surgery，fat liquefaction and incision infection were compared between the two groups. Results The speed of incision suture in the study group was slower than that in the control group (P＜0.05)，the suture time in the study group was longer than that in the study group (P＜0.05)，and the area of scar in the study group was smaller than that in the control group (P＜0.05)，and the total incidence of complications in the study group were lower than that in the control group (P＜0.05)，and the class A healing rate of incision in the study group was higher than that in the control group (P＜0.05). There was no significant difference between the two groups in pain score on the 3rd day after surgery and healing time (P＞0.05). Conclusion Intradermal suture applied in thoracoscopic lobectomy can significantly reduce scar hyperplasia，achieve less scar or even no scar，which is worthy of all-round promotion and application. 2020 Vol. 27 (18): 77-79转83 [Abstract] ( 80 ) HTML (35 KB)  PDF  (0 KB)  ( 5 ) 80 Application effect of ankle joint stress test in patients with ankle joint supination-external rotation fracture DU Ming-hua； TANG Yue-song； LIU Chuan-fang； ZHONG Xiang-ming Objective To investigate the clinical effect of ankle stress test in patients with ankle joint supination-external rotation fracture. Methods A total of 56 patients with ankle joint supination-external rotation fracture admitted to our hospital from October 2018 to May 2019 were selected as subjects. According to the random number table method，the patients were divided into control group and observation group，28 cases in each group. The control group was classified by X-ray，while the observation group was classified by X-ray + ankle stress test. The American orthopedic foot and ankle association (AOFAS) ankle-posterior foot score，treatment effect，and quality of life were compared between the two groups. Results In the observation group，there were 18 cases (64.29%) of ankle stress test (+) and 10 cases(35.71%) of ankle stress test (-). Three months after treatment，the AOFAS ankle-posterior foot score in the observation group was higher than that in the control group，with statistically significant difference (P＜0.05). The total effective rate of the observation group was 96.43%，higher than that of the control group (78.57%)，and the difference was statistically significant (P＜0.05). The scores of mental health，emotional function，social function，vitality，overall health，physical pain，physiological function and physiological function of the patients in the observation group were all higher than those in the control group，and the differences were statistically significant (P＜0.05). Conclusion The ankle joint stress test of ankle joint in the treatment of patients with ankle joint supination-external rotation fracture can clarify the classification of fibula fractures complicated with triangular ligament injuries，improve ankle and foot functions through targeted treatment，improve the treatment effect，and have positive significance for the quality of life of patients 2020 Vol. 27 (18): 80-83 [Abstract] ( 74 ) HTML (33 KB)  PDF  (0 KB)  ( 8 ) 84 Clinical effect comparison of manual traction closed reduction and traction bed closed reduction in internal fixation of proximal femoral nail antirotation treatment for patients with intertrochanteric fractures CAI Yun-shan； XU Hai-wang； HUANG Guang-sen Objective To compare the clinical effect of manual traction closed reduction and traction bed closed reduction in proximal femoral nail antirotation (PFNA) internal fixation treatment for patients with intertrochanteric fractures.Methods A retrospective analysis was conducted on a total of 60 patients with intertrochanteric fractures treated in our hospital from October 2018 to April 2019. They were divided into control group (n=30) and observation group (n=30) by different research methods. Patients in the control group were treated with traction bed closed reduction in PFNA internal fixation，and in the observation group，they were treated with manual traction closed reduction in PFNA internal fixation. The operation time，frequency of X-ray exposures，intraoperative bleeding volume，fracture healing time，excellent and good rate of Harris score of hip joint，visual analogue scale (VAS) and complications were observed. Results The operation time in the observation group was shorter than that of the control group； the frequency of X-ray exposures and intraoperative bleeding volume in the observation group were less than those of the control group； the VAS score and the total incidence of complications in the observation group were lower than those of the control group； all the differences were statistically significant (P＜0.05). But there were no significant differences in fracture healing time or Harris score between the two groups (P＞0.05). Conclusion Compared with traction bed，manual traction closed reduction in PFNA internal fixation treatment has a better clinical effect in treating intertrochanteric fractures. 2020 Vol. 27 (18): 84-86 [Abstract] ( 63 ) HTML (33 KB)  PDF  (0 KB)  ( 8 ) 87 Effect comparison of arthroscopic anterior cruciate ligament reconstruction at different time points in treatment for unilateral anterior cruciate ligament injury LI Can-hui; WU Jing-xiong Objective To investigate clinical effect of arthroscopic anterior cruciate ligament reconstruction at different time points in treatment for unilateral anterior cruciate ligament injury. Methods A total of 148 patients with unilateral anterior cruciate ligament injury treated in our hospital from January to December 2019 were selected as subjects，and they were divided into two groups by random number table method，74 cases in each group. The control group received arthroscopic anterior cruciate ligament reconstruction after injury 3 weeks. The observation group received arthroscopic anterior cruciate ligament reconstruction within injury 3 weeks. The joint range of motion and knee function were measured before and after treatment. The clinical efficacy and complications of the two groups were compared. Results After treatment，the joint range of motion，Tegner knee motion standard (Tegner) score，IKDC knee joint evaluation system (IKDC) score and Lysholm knee joint scale (Lysholm) score of patients in the two groups were all higher than those before treatment，and the differences were statistically significant (P＜0.05). The Kt2000 30° and Kt2000 90° of patients in the two groups after treatment were lower than those before treatment，and the differences were statistically significant (P＜0.05). After treatment，the joint range of motion，Tegner score，IKDC score and Lysholm score of the observation group were all higher than those of the control group，with statistically significant differences (P＜0.05). The Kt2000 30° and Kt2000 90° in the observation group after treatment were lower than those in the control group，and the differences were statistically significant (P ＜0.05).The total effective rate of the observation group was higher than that of the control group，and the difference was statistically significant (P＜0.05). The total incidence of complications in the observation group was lower than that in the control group，and the difference was statistically significant (P＜0.05). Conclusion Arthroscopic anterior cruciate ligament reconstruction within injury 3 weeks can significantly improve knee function，which can also improve efficacy and safety. 2020 Vol. 27 (18): 87-90 [Abstract] ( 71 ) HTML (38 KB)  PDF  (0 KB)  ( 9 ) 91 Short-term clinical effect of spinal pelvic internal fixation in the treatment of Tile C posterior pelvic ring fractures YAO Fu-hua; LIANG Jian-bin; MAO Li-fei; SU Yi-fan; XIAO Qian-ren Objective To investigate the short-term clinical effect of spinal pelvic internal fixation in the treatment of Tile C posterior pelvic ring fractures. Methods A total of 38 patients with Tile C posterior pelvic ring fracture treated in our hospital from January 2015 to August 2019 were selected and divided into the observation group (28 patients，received spinal pelvic internal fixation) and the control group (10 patients，received open plate internal fixation) according to different treatment methods. The short-term clinical effect of the two groups was compared. Results The operation time of the observation group was shorter than that of the control group，the amount of bleeding of the observation group was less than that of the control group，and the failure rate of internal fixation of the observation group was lower than that of the control group，the differences were statistically significant (P＜0.05). The excellent and good condition of Majeed scores in the observation group at 1 and 3 months after operation were better than those in the control group，the differences were statistically significant (P＜0.05). Conclusion Compared with the traditional open plate internal fixation，spine pelvis internal fixation can shorten the operation time of Tile C posterior pelvic ring fracture patients，reduce the amount of bleeding，improve the success rate of internal fixation，and improve the Majeed score，which is worthy of clinical promotion and application. 2020 Vol. 27 (18): 91-93 [Abstract] ( 74 ) HTML (33 KB)  PDF  (0 KB)  ( 9 ) 94 Analysis of the correlation between the changes of femoral positioning point and graft diameter and the rotational stability of knee joint in anterior cruciate ligament reconstruction LIU Yang; YIN Tian; BI Fang-shan; HOU Yun-jie; NIU Kai; CHEN Wen-xue; ZHAO Xing-wei; WANG Xin-xin Objective To investigate the correlation between the changes of femoral positioning point and graft diameter and the rotational stability of knee joint in anterior cruciate ligament reconstruction. Methods From January 2014 to March 2019，60 patients with anterior cruciate ligament injury in our hospital were selected as the study objects，anterior cruciate ligament reconstruction was performed，and CT examination was performed after operation. The following two experiments were carried out respectively. In experiment 1，ensuring the same graft diameter，the correlation between different tunnel positioning points and knee rotation stability was analyzed. In experiment 2，ensuring the femoral side positioning point was consistent，each group was divided into according to different control tunnel diameters，grouping was corried out，30 cases in each groups. When the control tunnel diameter was 7 mm，they were divided into group a (n=18) and group A (n=12) according to different distances. When the control tunnel diameter was 8 mm，they were divided into group b (n=13) and group B (n=17) according to different distances. In experiment 2，the control tunnel diameter of 7 mm were selected as group c (n=30). The control tunnel diameter of 8 mm were selected as group d(n=30). The correlation between the different tunnel diameter and the rotation stability of knee joint was analyzed. In the two groups of experiments，the change of the distance of trochlear groove (TT-TG value) was observed，and the TTTG value of patients was observed，and the correlation between the two groups of experiments and the rotation stability of knee joint was analyzed. Results In experiment 1，the TT-TG value in group a was significantly lower than that in group A when the tunnel diameter was controlled to be 7 mm，the difference was statistically significant (P＜0.05). In group b，the TT-TG value was significantly lower than that in group B when the tunnel diameter was controlled to be 8 mm，the difference was statistically significant (P＜0.05). Correlation analysis showed that the positioning point was positively correlated with the rotational stability of the knee joint (P＜0.05). In experiment 2，there was no significant difference in the TT-TG value between group c and group d when the positioning point range was constant (P＞0.05). Correlation analysis showed that there was no correlation between the change of graft diameter and the rotation stability of knee joint (r=0.3617，P=0.0716). Conclusion There is no correlation between the change of the graft diameter and the rotational stability of the knee joint in anterior cruciate ligament reconstruction，but there is a positive correlation between the femoral positioning point and the rotational stability of the knee joint. Therefore，it is necessary to pay more attention to the femoral positioning point to make it accurate. 2020 Vol. 27 (18): 94-96 [Abstract] ( 69 ) HTML (30 KB)  PDF  (0 KB)  ( 12 ) 97 Clinical effect of Iron Sucrose combined with Recombinant Human Erythropoietin in the treatment of hip fracture combined with anemia in the middle-aged and elderly patients YANG Hong-zhi； HU Bin； YANG Yong-hua； WANG Xi-chun； GAO Zhan-wang； YANG Min-jie； YANG Hai-long Objective To explore the clinical effect of Iron Sucrose combined with Recombinant Human Erythropoietin in the treatment of hip fracture combined with anemia in the middle-aged and elderly patients. Methods A total of 40 middle-aged and elderly patients with hip fracture combined with anemia in Jiujiang First People′s Hospital from October 2018 to November 2019 were selected as the research subjects. They were divided into observation group (n=20)and control group (n=20) by random method of drawing lots. In the control group，patients were treated with Iron Sucrose，and in the observation group，they were treated with Iron Sucrose combined with Recombinant Human Erythropoietin. The blood transfusion rate，total effective rate，ferritin (SF) level，hemoglobin (Hb) level and total incidence of complications were compared between the two groups. Results The blood transfusion rate (0.00%) and the total incidence of complications (35.00%) in the observation group were lower than those in the control group (30.00%，5.00%)，with statistically significant differences (P＜0.05). After treatment，the SF level of patients in the observation group (［81.67±4.39］ μg/L) was lower than that of the control group (［134.55±11.42］ μg/L)，and the Hb level (［126.95±15.78］ g/L) was higher than that of the control group (［112.15±13.87］ g/L)，the differences were statistically significant (P＜0.05). The total effective rate of the observation group was 95.00%，which was higher than that of the control group (75.00%)，and the difference was statistically significant (P＜0.05). Conclusion Sucrose Iron combined with Recombinant Human Erythropoietin has a significant therapeutic effect in the treatment of middle-aged and elderly patients with hip fracture combined with anemia，it is worthy of clinical application. 2020 Vol. 27 (18): 97-99转103 [Abstract] ( 75 ) HTML (33 KB)  PDF  (0 KB)  ( 12 ) 100 Clinical effect of low-frequency sparse-dense wave combined with Jiegu Qili Tablets in treatment of lumbar vertebral compression fractures XU Yan Objective To observe clinical effect of low-frequency sparse-dense wave combined with Jiegu Qili Tablets in treatment of lumbar vertebral compression fractures (LVCF). Methods Fifty patients with osteoporotic LVCF who were admitted to our hospital from April 2017 to April 2019 were enrolled. According to random number table method，they were divided into control group and observation group，25 cases in each group. The control group was treated with Jiegu Qili Tablets，while observation group was additionally treated with low-frequency sparse-dense wave. The curative effect of both groups after treatment was observed. The changes in scores of visual analogue scale (VAS)，bone mineral density (BMD) and levels of bone metabolism indexes before and after treatment were compared. Results After treatment，the total effective rate of the observation group was 92.00%，which was higher than 68.00% of the control group，and the difference was statistically significant (P＜0.05). After treatment，the VAS scores of both groups were lower than those before treatment，and the observation group was lower than the control group，the bone mineral density levels of both groups were higher than those before treatment，and the observation group was higher than the control group，the differences were statistically significant (P＜0.05). After treatment，the levels of type Ⅰprocollagen carboxyterminal pro-peptide (PⅠCP)，osteocalcin (BPG) and bone alkaline phosphatase (BALP) of in the two groups were higher than those before treatment，and the levels in the observation group were higher than those in the control group，the differences were statistically significant (P＜0.05). Conclusion Low-frequency sparse-dense wave combined with Jiegu Qili Tablets can effectively alleviate pain in patients with osteoporotic LVCF，and accelerate bone healing. 2020 Vol. 27 (18): 100-103 [Abstract] ( 96 ) HTML (33 KB)  PDF  (0 KB)  ( 10 ) 104 Clinical study on the changes of pulmonary function in infants with pertussis syndrome before and after treatment FU Hong-gen; XU Dan-dan Objective To explore the changes of pulmonary function in infants with pertussis syndrome before and after treatment. Methods A total of 63 cases of pertussis syndrome in our hospital from June 2018 to November 2019 were selected as the treatment group，and 52 cases of healthy infants who had physical examination in the outpatient department were selected as the control group. The lung function level of the control group and the treatment group before and after treatment were compared and the therapeutic effect of the treatment group was analyzed. Results Before treatment，the respiratory rate (RR) of the treatment group was higher than that of the control group，the tidal volume (VT)，inspiratory/expiratory ratio (Ti/TE)，peak volume ratio (VPTEF/VE)，and peak time ratio (TPTEF/TE) were lower than those of the control group，the differences were statistically significant (P ＜0.05)； after treatment，RR，VT，Ti/TE，VPTEF/VE and TPTEF/TE of the treatment group were (24.98±0.21) times/min，(8.76±0.16) ml/kg，(0.81±0.13)%，(27.78±8.34)%，(38.84±7.32)%，respectively，before treatment for (28.56±5.64) time/min，(5.32±1.22) ml/kg，(0.70±0.10)%，(21.49±5.38)%，(21.88±6.69)%，RR in the treatment group was lower than that before treatment，VT，Ti/TE，VPTEF/VE and TPTEF/TE were higher than those before treatment，the differences were statistically significant (P＜0.05). All 25 cases were cured (39.68%)，18 cases were effective (28.57%)，14 cases were effective (22.22%)，3 cases were ineffective (4.76%). The effective rate was 95.24% (60/63). Conclusion The lung function of pertussis syndrome in infants is damaged. The detection of lung function can evaluate the condition of children，guide the treatment and improve the condition. 2020 Vol. 27 (18): 104-106 [Abstract] ( 52 ) HTML (31 KB)  PDF  (0 KB)  ( 9 ) 107 Clinical characteristics and treatment strategies of children with esophageal foreign body caused by button battery LIU Shao-feng； FENG Shuang； HUANG Zhen-yun； SUN Chang-zhi Objective To analyze the clinical characteristics and treatment strategies of children with esophageal foreign bodies caused by button batteries. Methods A total of 72 children with esophageal foreign bodies caused by button batteries in our hospital from January 2014 to June 2019 were selected as the study objects，and their clinical characteristics，degree of injury，treatment results and complications were analyzed. Results Among 72 children with esophageal foreign bodies caused by button battery，64 cases had vomiting，55 cases had difficulty swallowing，3 cases had nausea，and 14 cases had salivation. All of them had esophageal mucosal burns to varying degrees. After rigid esophageal microscopy and foreign body removal under general anesthesia，both of them were discharged smoothly. A total of 8 children had esophageal perforation. The incidence of esophageal perforation in the middle esophagus was higher than that in the upper and lower esophagus，and the difference was statistically significant (P＜0.05). Conclusion Children with esophageal foreign bodies caused by button batteries have symptoms of vomiting and dysphagia，which are likely to cause esophageal mucosal erosion and esophageal perforation. Early removal of foreign bodies is required to improve prognosis. 2020 Vol. 27 (18): 107-109转113 [Abstract] ( 50 ) HTML (33 KB)  PDF  (0 KB)  ( 10 ) 110 Clinical effect of Laparoscopic partial resection of the fallopian tube and end-to-end anastomosis for the treatment of recurrent tubal pregnancy JIANG Xiao-lan； KANG Jia-li； ZHANG Xiao-yan； TANG Wei； CHEN Yan-mei； GONG Yan-mei Objective To study the efficacy and pregnancy outcome of laparoscopic partial fallopianectomy and endto-end anastomosis for recurrent tubal pregnancy. Methods A total of 60 patients with ampulla or isthmus pregnancy who were admitted to our hospital from January 2014 to December 2018 were selected as the research objects. They were divided into observation group and control group according to the principle of random grouping. The observation group was treated with laparoscopic partial salpingectomy and end-to-end anastomosis，and the control group was treated with laparoscopic tubal pregnancy removal (including fenestration and incision embryo suture). Surgical time，intraoperative blood loss，postoperative hospitalization time，postoperative decrease in human choionic gonadotophin(HCG)，incidence of persistent ectopic pregnancy，and incidence of tubal on the affected side Unobstructed condition(uterine fallopian tube angiography) and postoperative intrauterine pregnancy rate were compared between two groups.Results The operation time was (74.5±5.3) d in the observation group，longer than that in the control group for (53.5±4.7) d，and the difference was statistically significant (P＜0.05)； the intraoperative blood loss was (25.6±5.2) ml and postoperative hospital stay was (4.0±2.9) d in the observation group，compared with the control group for (30.1±4.8) ml，(4.0±3.7) d，the differences were not statistically significant (P＞0.05)； the blood HCG in patients in the observation group decreased 3 d and 2 weeks after surgery was (82.5±5.4)，(91.2±2.7) mIU/ml，which was higher than that in the control group for (65.5±4.8)，(98.4±1.6) mIU/ml，the differences were statistically significant (P＜0.05)； the incidence of persistent ectopic pregnancy in the observation group was (0.00%) lower than that of the control group (10.00%)，the difference was statistically significant (P＜0.05).The tubal patency of the observation group was better than that of the control group，and the rate of intrauterine pregnancy again was higher than that of the control group，the differences were statistically significant (P＜0.05). Conclusion Laparoscopic partial fallopian tube resection and end-to-end anastomosis for the treatment of recurrent tubal pregnancy can reduce the incidence of persistent ectopic pregnancy，improve the intrauterine pregnancy rate after surgery，thereby reducing the damage caused by assisted reproduction to the patient′s body and reducing the patient′s economy. 2020 Vol. 27 (18): 110-113 [Abstract] ( 69 ) HTML (37 KB)  PDF  (0 KB)  ( 12 ) 114 Prediction of preterm birth by combined detection of cervical length and intercellular adhesion molecule-1 in serum of pregnant women PENG Jing; HUANG Ya; ZHU Li-xian; ZHONG Jie; LIANG Yan-qin; ZHANG Fen; ZHAO Ming-jie Objective To explore the predictive value of cervical length and intercellular adhesion molecule-1 (ICAM-1) in serum of pregnant women. Methods A total of 241 parturients with single pregnancy in our hospital from January 2018 to October 2019 were selected. According to the pregnant state and the gestational age at delivery they were divided into healthy control group (n=90)，threatened preterm delivery group (n=88) and preterm delivery group (n=63).The cervical length and serum ICAM-1 concentration were measured in all the parturients. The above indexes of the three groups were compared to evaluate the predictive value of cervical length and ICAM-1 on preterm delivery. Results the cervical length of preterm delivery group was shorter than that of healthy control group and threatened preterm delivery group，and the serum ICAM-1 level of preterm delivery group was higher than that of the other two groups，with statistical differences (P＜0.05)； the positive rate of cervical length and serum ICAM-1 in preterm delivery group was higher than that of healthy control group (P＜0.05)； the sensitivity and negative predictive value of cervical length combined with serum ICAM-1 were higher than those of single index diagnosis. Conclusion The combination of cervical length and serum ICAM-1 has a high predictive value for the occurrence of preterm delivery in pregnant women，which is worthy of clinical application. 2020 Vol. 27 (18): 114-116 [Abstract] ( 60 ) HTML (35 KB)  PDF  (0 KB)  ( 14 ) 117 Application of WeChat platform health education in patients with ectopic pregnancy HU Yan; ZHOU Li-hong; CAI Ai-lian Objective To explore the application effect of WeChat platform health education in patients performing with ectopic pregnancy. Methods From January 2017 to January 2019，80 ectopic pregnancy women treated in Department of Obstetrics and Gynecology，Jiangxi Medical College were selected as the research subjects. They were divided into the control group (n=40) and the observation group (n=40) according to the different nursing methods. In the control group，routine nursing was used，while in the observation group，routine nursing combined with WeChat platform health education nursing was adopted. The total nursing satisfaction between the two groups was compared. The disease cognitive status survey score，quality of life (QOL) score，self-rating anxiety scale (SAS)，and self-depression rating scale(SDS) score on the day of discharge and 1 month after discharge were compared. Results The total satisfaction of nursing in the observation group was higher than that in the control group，and the difference was statistically significant(P＜0.05). The disease cognitive status survey score in the observation group at 1 month after discharge was higher than that on the day of discharge and the control group with statistical differences (P＜0.05). The QOL scores in the observation group at 1 month after discharge were higher than those on the day of discharge and the control group，and the differences were statistically significant (P＜0.05). The SAS and SDS scores at 1 month after discharge in the observation group were lower than those the day of discharge and the control group with statistical differences (P＜0.05). Conclusion The selection of health education nursing service based on WeChat platform for women with ectopic pregnancy can help to increase their correct cognition of disease，ameliorate their QOL，alleviate their negative emotions，and improve their nursing satisfaction. 2020 Vol. 27 (18): 117-119 [Abstract] ( 59 ) HTML (33 KB)  PDF  (0 KB)  ( 8 ) 120 Effect of body position management combined with bare hand rotation of fetal head on delivery outcome of primipara ZHANG Xiao-ling； LIANG Hai-yong； XIE Hui-hui Objective To observe and analyze the influence of position management assisted by bare hand rotation of fetal head on the pregnancy outcome of primipara. Methods A total of 1080 primiparas admitted to our hospital from June 2018 to May 2019 were selected as the study objects. According to the random number table method they were divided into the control group (n=540)and the observation group (n=540).The control group used conventional midwifery，and the observation group used body position management to assist in freehand rotation of fetal head. Methods of delivery，duration of labor and complications of delivery were compared between the two groups. Results The rate of natural delivery in the observation group was higher than that in the control group，and the rate of instrument delivery and cesarean section was lower than that in the control group (P＜0.05).In the observation group，the rate of second degree laceration and perineal incision was lower than that in the control group，and the rate of perineal completion was higher than that in the control group (P＜0.05). The first，second and total labor stages of the observation group were shorter than those of the control group (P＜0.05). The incidence of postpartum hemorrhage，secondary uterine inertia and postpartum urinary retention in the observation group were lower than those in the control group (P＜0.05). There was no significant difference in the incidence of neonatal asphyxia，cervical laceration and amniotic fluid pollution between the two groups (P＞0.05). Conclusion During the stage of labor，the body position management and the free-hand rotation of the fetal head can effectively reduce the risk of midwifery of the cesarean section and the device，shorten the time of first and second labor，reduce the postpartum hemorrhage rate，reduce the degree of perineal injury，and reduce the occurrence of secondary uterine contraction and post-partum urine retention. And the delivery safety is improved，and the effect is remarkable. 2020 Vol. 27 (18): 120-122转126 [Abstract] ( 44 ) HTML (36 KB)  PDF  (0 KB)  ( 11 ) 123 Clinical effect of the combination of Chorionic Gonadotropin and Human Chorionic Gonadotropin in the treatment of infertility due to hypogonadotropic amenorrhea LI Yan Objective To explore the clinical effect of urinary gonadotropin (HMG)，human chorionic gonadotropin(HCG) combined with artificial cycle therapy in the treatment of infertility caused by low gonadotropin amenorrhea.Methods A total of 120 cases of infertility caused by low gonadotropin amenorrhea treated in our hospital from November 2017 to April 2019 were selected as the research subjects. They were divided into control group and treatment group by random number table method，60 cases in each group. The control group used conventional artificial cycle.The treatment group was treated with HMG，HCG combined with artificial cycle therapy. The pregnancy success rate，endometrial thickness，uterine volume，ovarian volume，dominant follicles，and hormone levels were compared between the two groups. Results The pregnancy success rate in the treatment group was higher than that in the control group，and the difference was statistically significant (P＜0.05)； the endometrial thickness，uterine volume，and ovarian volume in the treatment group were greater than those in the control group，and the differences were statistically significant (P＜0.05). The dominant follicles in the treatment group were more than that in the control group，the difference was statistically significant (P＜0.05)； the hormone level in the treatment group was higher than that in the control group，the difference was statistically significant (P＜0.05). Conclusion The administration of HMG and HCG combined with artificial cycle therapy for infertility patients caused by low gonadotropin amenorrhea has significant effect，which can effectively increase the thickness of the endometrium，uterine volume and the number of dominant follicles，and improve hormone levels，thereby increasing the success rate of pregnancy，have high clinical application value and are worth promoting. 2020 Vol. 27 (18): 123-126 [Abstract] ( 62 ) HTML (35 KB)  PDF  (0 KB)  ( 8 ) 127 Clinical effect of Sodium Creatine Phosphoate combined with Energy Mixture in treating children with myocarditis LIU Dan Objective To investigate the clinical effect of Sodium Creatine Phosphate combined with Energy Mixture in treating myocarditis in children. Methods Sixty-eight children with myocarditis who were treated in our hospital from November 2018 to November 2019 were selected as the research objects，and different treatment schemes were used as the basis for grouping，that was 34 children treated with a single Energy Mixture were set as a single group. The 34 children who received Sodium Creatine Phosphate on the basis of the Energy Mixture were set as the combination group. The changes of myocardial enzyme levels before and after treatment were compared between the two groups，and the curative effect and total incidence of adverse reactions were observed in the two groups. Results Before treatment，there were no significant differences in myocardial enzyme levels between the two groups (P＞0.05)； after treatment，the myocardial enzyme levels of the two groups had decreased，and the myocardial enzyme levels of the combined group were lower than those of the single group，and the differences were statistically significant (P＜0.05). After treatment，the total effective rate of the combined group was higher than that of the single group (97.06%＞70.59%)，with statistical difference (P＜0.05). After treatment，there was no significant difference in the total incidence of adverse reactions between the two groups (P＞0.05). Conclusion The combined application of Sodium Creatine Phosphate and Energy Mixture in the treatment of children with myocarditis has a positive effect on the improvement of myocardial enzyme levels in children，and the treatment is safer. 2020 Vol. 27 (18): 127-129 [Abstract] ( 56 ) HTML (31 KB)  PDF  (0 KB)  ( 9 ) 130 Application value of chromosome microarray technology in prenatal diagnosis of fetal ultrasound abnormalities LI Luo-bing； TAN Man-sheng； LIANG Xi-lan； PAN Jin-mei； CHEN Xiao-le Objective To explore the application value of chromosomal microarray technology (CMA) in prenatal diagnosis of fetal ultrasound abnormalities. Methods From January 2017 to October 2019，146 pregnant women diagnosed with ultrasound abnormalities at the prenatal diagnosis center of Maoming Maternal and Child Health Hospital were selected as the research subjects，and the CMA examination and karyotype test were performed. Results The karyotype analysis and CMA of 146 fetuses were successfully detected. 22 cases of chromosome karyotype analysis showed abnormal results. The detection rate of chromosome abnormalities was 15.07% (22/146)，24 cases of pathogenic copy number variation (CNVs)，4 cases of clinically unclear copy number variation (VOUS) were detected by CMA. Multiple deformities (6/24)，cardiovascular system (6/24)，central nervous system (4/24)，and fetal neck clear layer (NT) thickening (7/24) were the most relevant to pathogenic CNVs. The detection rate of CMA chromosome abnormalities was 19.18% (28/146). 1 case of chromosome inversion，1 case of chromosome chimera，and 20 cases of same chromosome karyotype were detected by CMA. For chromosomal imbalance mutations，abnormalities could be detected by traditional karyotype analysis techniques，and CMA technology can show more accurate abnormality sites. 8 cases with normal karyotype and abnormal CMA results were microdeletions and microduplications. The CMA positive detection rate increased by 4.11%. Conclusion Compared with traditional karyotype analysis，CMA improves the positive detection rate of chromosome karyotype in fetal ultrasound abnormal cases，and can better avoid birth defects. 2020 Vol. 27 (18): 130-132转141 [Abstract] ( 59 ) HTML (31 KB)  PDF  (0 KB)  ( 7 ) 133 Application and clinical significance of pelvic floor ultrasound in female patients with pelvic floor dysfunction TU You-mei ； CHEN Guan-chun； LYU Xiao-liang Objective To investigate the application and clinical significance of pelvic floor ultrasound in female patients with pelvic floor dysfunction. Methods A total of 32 female patients with pelvic floor dysfunction treated in our hospital from February 2018 to March 2019 were selected as the study group. At the same time，30 female patients with non-pelvic floor dysfunction were selected as the control group. The patients in the two groups were given pelvic floor ultrasound respectively. the transverse diameter of (N)，anal levator muscle foramen and posterior diameter (M).Thickness of pubic visceral muscle (C)，area of foramen foramen of levator anal muscle (A) and the angle between the left and right branches of the levator anal muscle (γ) of ultrasound at the resting state，anus contraction state and Valsalva state were compared between the two groups. Results The N and M of the study group at the resting state，anus contraction state and Valsalva state were longer than those of the control group，the C of the study group at the resting state，anus contraction state and Valsalva state was thicker than that of the control group，the A and γ of the study group at the resting state，anus contraction state and Valsalva state were larger than those of the control group，and the difference were statistically significant (P＜0.05). Conclusion Pelvic floor ultrasound can provide timely and effective information support for the diagnosis and treatment of female patients with pelvic floor dysfunction. It is beneficial to formulate targeted treatment measures and has high application value. 2020 Vol. 27 (18): 133-135 [Abstract] ( 65 ) HTML (30 KB)  PDF  (0 KB)  ( 8 ) 136 Comparison application of magnetic resonance and color Doppler ultrasound in the diagnosis of prostate diseases LUO Jian-hua； ZHU Lv-ming； YU Zhi-ru； QIU Qin-wen； ZENG Qing-liang Objective To explore the comparison application of magnetic resonance (MR) plain scan，MR dynamic-enhanced scan and color Doppler ultrasound in the diagnosis of prostate diseases. Methods A total of 30 patients suspected with prostate diseases treated in the urology department of our hospital from July 2014 to July 2018 were selected as research subjects. All patients were examined with Philips 1.5 Tesla MR plain scan，MR dynamic-enhanced scan and color Doppler ultrasound. The transrectal pathology biopsy was selected as the ＂golden standard＂ for diagnosis，the value of MR plain scan，MR dynamic-enhanced scan and color Doppler ultrasound in the diagnosis of prostate diseases was compared. Results The sensitivity of MR dynamic-enhanced scan for the diagnosis of prostate diseases was 95.65%，which was higher than that of MR plain scan and color Doppler ultrasound accounting for 86.95% and 78.28%，respectively，the differences were statistically significant (P＜0.05). The specificity of MR plain scan for the diagnosis of prostate diseases was 85.71%，which was higher than that of MR dynamic-enhanced scan and color Doppler ultrasound accounting for 71.42% and 42.85%，respectively，the differences were statistically significant (P＜0.05). The accuracy rate of MR dynamic-enhanced scan for the diagnosis of prostate diseases was 90.00%，which was higher than that of color Doppler ultrasound and MR plain scan accounting for 70.00% and 83.33%，respectively，the differences were statistically significant (P＜0.05). Conclusion MR dynamic-enhanced scan can provide more opportunities of early diagnosis and early treatment for patients with prostate diseases，improve their cure rate and quality of life. It is worthy of learning and reference in clinical diagnosis. 2020 Vol. 27 (18): 136-138 [Abstract] ( 66 ) HTML (32 KB)  PDF  (0 KB)  ( 9 ) 139 Clinical value of abdominal ultrasound combined with vaginal ultrasound in the diagnosis of acute abdomen in Department of Obstetrics and Gynecology LIU Nian Objective To investigate the clinical value of abdominal ultrasound combined with vaginal ultrasound in the diagnosis of acute abdomen in Department of Obstetrics and Gynecology. Methods A total of 90 patients with acute abdomen in Department of Obstetrics and Gynecology in our hospital from March 2018 to March 2019 were selected and divided into the control group and the observation group by blind grouping，with 45 patients in each group. The control group underwent simple abdominal ultrasound examination，and the observation group underwent abdominal ultrasound combined with vaginal ultrasound examination. The diagnostic specificity，sensitivity and accuracy of gynecological acute abdomen in the two methods of examination were compared. Results The specificity，sensitivity and accuracy of acute abdomen in Department of Obstetrics and Gynecology diagnosis in the examination method of abdominal ultrasound combined with vaginal ultrasound were higher than those in the simple abdominal ultrasound examination (P＜0.05). Conclusion The application of abdominal ultrasound combined with vaginal ultrasound in the diagnosis of acute abdomen in Department of Obstetrics and Gynecology is ideal. It can significantly improve the accuracy of disease diagnosis and has certain clinical promotion value. 2020 Vol. 27 (18): 139-141 [Abstract] ( 57 ) HTML (28 KB)  PDF  (0 KB)  ( 12 ) 142 Effect analysis of clinical pharmacist intervention on antimic use density in department of intrarenal rheumatology and immunology ZENG Yan-cong; LI Xiang; HUANG Shuang-ying; CHEN Bo Objective To explore the changes of antibiotic use intensity of hospitalized patients in department of intrarenal rheumatology and immunology before and after intervention by clinical pharmacists，so as to improve the rational use of antibiotic in department of intrarenal rheumatology and immunology. Methods The data of all antibacterial drugs in the department of intrarenal rheumatology and immunology in our hospital before the intervention (June to December 2018) were retrospectively investigated. Through reviewing the medical records and prescriptions of antibacterial drugs in this department，the reasons were found out，the objectives were determined，the countermeasures were formulated and the intervention was implemented. Clinical pharmacists actively participated in the whole process of antibacterial drug management. The antibacterial drug use intensity and irrational use of antibacterial drugs of hospitalized patients before and after the intervention (January to July 2019) were compared. Results After the intervention，the use intensity，cost and irrational use of antibacterial drugs in department of intrarenal rheumatology and immunology were all lower than those before the intervention，and the differences were statistically significant (P＜0.01). Conclusion The active participation of clinical pharmacists can effectively reduce the use intensity and cost of antibacterial drugs and improve the rational application of antibacterial drugs in department of intrarenal rheumatology and immunology. 2020 Vol. 27 (18): 142-145 [Abstract] ( 65 ) HTML (35 KB)  PDF  (0 KB)  ( 14 ) 146 Application of Alteplase combined with Clopidogrel in patients with acute ischemic mild stroke MING Zi-xin Objective To explore the application of Alteplase combined with Clopidogrel in patients with acute ischemic mild stroke (AIMS). Methods A total of 154 patients with AIMS admitted to our hospital from January 2018 to May 2019 were selected. According to the random number table method，they were divided into observation group and control group，with 77 cases in each group. Patients in the control group received conventional methods of lowering blood glucose and blood pressure besides Alteplase treatment. In the observation group，on the basis of the control group，Clopidogrel was added. Followed up for 3 months，the National Institute of Health stroke scale (NIHSS) score and the modified Rankin scale score，laboratory indicators，Barthel index and activity of daily living (ADL) score，and adverse events were compared in the two groups. Results The NIHSS and modified Rankin scale scores of the observation group after treatment were lower than those of the control group，and the differences were statistically significant(P＜0.05). The Barthel index and ADL score of the observation group after treatment were higher than those of the control group with statistical significances (P＜0.05). There were no significant differences in white blood cell count (WBC)，platelet count (PLT) and platelet count (FIB) between the two groups after treatment (P＞0.05). The total incidence of adverse events in the observation group was 2.60%，lower than 12.99% in the control group，and the difference was statistically significant (P＜0.05). Conclusion Alteplase combined with Clopidogrel is effective in the treatment of patients with AIMS and has a high safety. 2020 Vol. 27 (18): 146-148 [Abstract] ( 54 ) HTML (32 KB)  PDF  (0 KB)  ( 12 ) 149 Clinical effect of Estradiol Valerate in the adjuvant treatment of patients with senile vaginitis ZHU Jing Objective To explore the clinical effect of Estradiol Valerate in the adjuvant treatment of patients with senile vaginitis. Methods A total of 84 patients with senile vaginitis treated in our hospital from February 2016 to February 2019 were selected as research subjects. They were divided into observation group (n=42) and control group (n=42)according to random number table method. Patients in the control group received Lactobacillus Vagina Capsules orally，and in the observation group they received oral administration of Lactobacillus Vagina Capsules and Estradiol Valerate.The clinical efficacy，inflammatory factor levels of vaginal secretion，relapse rate and adverse reactions of the two groups were compared. Results The total effective rate of treatment in the observation group was 92.86%，higher than that of the control group accounting for 71.43% with statistical significance (P＜0.05). The levels of interleukin-6 (IL-6)，interleukin-8 (IL-8) and tumor necrosis factor-α (TNF-α) in the vaginal secretions before treatment in the two groups were compared without statistical significance (P＞0.05). After seven days of treatment，the levels of IL-6，IL-8 and TNF-α in the two groups were lower than those before treatment. The levels of IL-6，IL-8 and TNF-α in the observation group were lower than those of the control group，and the differences were statistically significant (P＜0.05).The relapse rate in the observation group during six months after treatment was 4.76%，lower than that of the control group accounting for 21.43%，with statistical significance (P＜0.05). No obvious adverse reactions occurred during the treatment of the two groups. Conclusion The use of Estradiol Valerate as an adjuvant therapy to treat patients with senile vaginitis can effectively improve clinical symptoms，reduce levels of inflammatory factors in vaginal secretion and relapse. It is safe，and is worthy of clinical promotion. 2020 Vol. 27 (18): 149-151 [Abstract] ( 53 ) HTML (31 KB)  PDF  (0 KB)  ( 11 ) 152 Geng Kai-yi′s clinical experience summary in treating hypomenorrhea LI Wen-qing; SUN Lu; GENG Kai-yi Hypomenorrhea is a disease name in traditional Chinese medicine and is a relatively common gynecological disease in clinic. In recent years，with the changes in the social environment，hypomenorrhea due to various reasons in clinical practice is common，and it has a significant impact on women who desire to have children. This article focuses on the summarization of the experience of Geng Kai-yi，a famous distinguished traditional Chinese medicine doctor from Jiangsu Province，who has 70 years of medical experience in treating hypomenorrhea，so that the essence of the country can be inherited. 2020 Vol. 27 (18): 152-154 [Abstract] ( 66 ) HTML (33 KB)  PDF  (0 KB)  ( 10 ) 155 Clinical application of Wei Zhong-min′s thoughts on "treating spleen to settle five viscera" HUANG Jun-yi; WEI Zhong-min; WANG Tong In the traditional Chinese medicine，the normal function of human body depends on the nutrition provided by the spleen and stomach. Regulating spleen and stomach not only can cure both spleen and stomach diseases，but also can cure other diseases. Professor Wei Zhong-min，a national-level famous doctor of traditional Chinese medicine，makes good use of classic prescriptions of traditional Chinese medicine，treating various medical diseases with the method of ＂treating spleen to settle five viscera＂. This article reflects professor Wei Zhong-min′s clinical idea and experience from four aspects: literature record，modern research，clinical application and clinical cases of ＂treating spleen to settle five viscera＂. 2020 Vol. 27 (18): 155-158 [Abstract] ( 78 ) HTML (39 KB)  PDF  (0 KB)  ( 13 ) 159 Clinical effect of acupuncture combined with self-made Tongru Decoction for the treatment of postpartum milk deficiency CHEN Feng Objective To explore the clinical effect of acupuncture combined with self-made Tongru Decoction for the treatment of postpartum milk deficiency. Methods From January 2018 to August 2019，postpartum milk deficiency women admitted to the obstetrics and gynecology department of our hospital were selected as the research subjects，and 80 cases of them were divided into the control group and the observation group according to the sealed envelope opaque method，40 cases in each group. The women in the control group were simply treated with self-made Tongru Decoction，and the women in the observation group combined with acupuncture on this basis. The clinical efficacy，traditional Chinese medicine symptom score and lactation scores before and after treatment in the two groups were compared. Results The total effective rate after treatment in the observation group was higher than that in the control group，and the difference was statistically significant (P＜0.05). After treatment，the traditional Chinese medicine symptom scores in the observation group were lower than those in the control group，and the differences were statistically significant (P＜0.05). Before treatment，there were no statistically significant differences in the amount of lactation，breast filling，milk quality，milk stasis and daily urination of infants scores in the two groups (P＞0.05). The lactation scores of the two groups after treatment were higher than those before treatment，and the lactation scores of the observation group after treatment were higher than those of the control group，the differences were statistically significant (P＜0.05). Conclusion The clinical effect of acupuncture combined with Tongru Decoction is more accurate，which can not only improve the clinical symptoms of the women，but also improve the quality of lactation. It is worthy of clinical promotion and application. 2020 Vol. 27 (18): 159-162 [Abstract] ( 65 ) HTML (34 KB)  PDF  (0 KB)  ( 8 ) 163 A preliminary study on the regularity of acupoint selection in pediatric rectocele in ancient and modern times GUO Kui; CHEN Shu Through the analysis of the polymorphism of the regularity of acupoint selection for the treatment of pediatric rectocele by ancient and modern medical doctors，it is found that the ancient and modern medical doctors treat pediatric rectocele with the holistic concept and syndrome differentiation as the guiding ideology，and with Buzhong Yiqi and Shengyang Gutuo as the principle of acupoint selection. Ancient and modern medical doctors all value the depth of acupuncture and the amount of moxibustion. But there are also great differences between ancient and modern literatures in the treatment of pediatric rectocele. Ancient doctors often use single-point prescription，modern doctors often use multi-point prescription. Ancient doctors pay attention to dosage and order，while modern doctors are more accurate in dosage and attach importance to the methods of reinforcing and reducing. The dialectic of qi，blood，body fluid is a common method used by ancient doctors，while modern doctors focus on the dialectic of zang-organs and etiology. Ancient doctors mainly use moxibustion therapy，modern doctors focus on the use of acupuncture and moxibustion therapy，increase the manipulation of massage，innovative use of acupoint injection therapy. The regularity of acupoint selection in pediatric rectocele provides a certain basis for future clinical practice. It is hoped that doctors can combine the medical experience of ancient and modern doctors to guide clinical work together. 2020 Vol. 27 (18): 163-166 [Abstract] ( 60 ) HTML (42 KB)  PDF  (0 KB)  ( 9 ) 167 Survey on the current status of contraceptive and birth control measures for women of childbearing age in Xinyu City after the release of the "twochild" policy HU Fei； ZHANG Bo-cheng； HU Yan-fei Objective To survey the current status of contraceptive and birth control measures for women of childbearing age in Xinyu City after the release of the ＂two-child＂ policy. Methods A survey of 500 women of childbearing age after marriage was conducted in Xinyu City from November 2016 to November 2019. The general information was very complete. The contraceptive measures for women of childbearing age were observed and counted. Demographic characteristics of women of childbearing age were observed and counted. The incidence of adverse reactions and contraceptive failure rates of various contraceptive measures were observed and statistically analyzed. Results A total of 500 questionnaires were distributed in this survey，all of which were returned and valid questionnaires，with the effective rate being 100.00%. Contraceptive measures for women of childbearing age were mainly condoms，followed by intrauterine device (IUD) contraception； only a few of women adopted fallopian tubal ligation，oral contraceptives，and contraceptive pills (membrane). Among the adverse reactions of various contraceptive measures，other methods (19.35%) had the highest incidence of adverse reactions，followed by oral contraceptives and contraceptive pills (membrane) (18.92%).The incidence rate of adverse reactions of IUD contraception was 11.49%，and the incidence of adverse reactions of condom and fallopian tubal ligation contraception was the lowest. In terms of contraceptive failure，the oral contraceptives and contraceptive pills (membrane) had the highest incidence of failure，other methods and IUD contraception also had certain incidence of failure，and condom contraception and fallopian tube ligation contraception had the highest safety，without occurrence of failures in contraception. Conclusion After the release of the ＂two-child＂ policy，contraceptive measures in women of childbearing age in Xinyu City are mainly condoms and IUD contraception. Various contraceptive measures have certain adverse reactions and contraceptive failures. Women of childbearing age need to combine actual conditions in selection of the appropriate contraceptive measures. 2020 Vol. 27 (18): 167-169转178 [Abstract] ( 42 ) HTML (32 KB)  PDF  (0 KB)  ( 9 ) 170 Study on the rational use of psychotropic drugs and common adverse reactions CHEN Yu-huang； YU Qiao； AN Zhong-yuan； YIN Lei Objective To analyze the information marked in the instructions of commonly used psychotropic drugs and objectively understand the adverse drug reactions (ADR)，so as to provide reference for promoting the rational clinical use of drugs. Methods A total of 92 commonly used instructions of oral psychotropic drugs at home and abroad collected from psychiatric specialty hospitals and over second-level general hospitals in our city were classified and reviewed，and various common ADR，medication and pharmacokinetic parameters of special population were analyzed synthetically. Results The ADR of common psychotropic drugs involved many organs or systems and was serious. There were many vague words like ＂following doctor′s advice or reducing or having not been determined or studied＂ in the medication of pregnant women，lactation，children and the elderly. Most psychotropic drugs had active metabolites，long drug half-life (T1/2) and high plasma protein binding rate，some drugs，such as selective serotonin reuptake inhibitors (SSRIs)had strong inhibition on P450. Conclusion Physicians，pharmacists，patients and their family members should work out individualized drug delivery plans in combination with the patients′ own physical and mental conditions，carefully combine medications，and improve the compliance of patients with drugs. 2020 Vol. 27 (18): 170-173 [Abstract] ( 65 ) HTML (37 KB)  PDF  (0 KB)  ( 7 ) 174 An epidemiological investigation report on a foodborne disease event caused by Vibrio parahaemolyticus YU Shu-jun Objective To carry out an epidemiological investigation on a foodborne disease event caused by Vibrio parahaemolyticus pollution，and to clarify its causes and preventive measures. Methods An epidemiological survey was conducted on 11 people who had an adverse reaction after eating in a restaurant in our district on September 19，2019，including investigation and analysis of the event，food situation，intervention measures and prognosis. Results The 11 people were all foodborne diseases caused by Vibrio parahaemolyticus pollution. After symptomatic intervention，the prognosis was good. Conclusion This foodborne disease is caused by diners eating food contaminated with Vibrio parahaemolyticus. In order to effectively control and reduce the incidence of Vibrio parahaemolyticus，the health supervision department should strengthen monitoring and management，and effectively grasp the basic characteristics of Vibrio parahaemolyticus. Catering service operators must abide by the relevant regulations to prevent food pollution，and aquatic product management institutions should be cleaned and disinfected regularly. 2020 Vol. 27 (18): 174-178 [Abstract] ( 57 ) HTML (41 KB)  PDF  (0 KB)  ( 8 ) 179 Study of occupational exposure risk in workers to anticancer drugs in pharmacy intravenous admixture service of a hospital YIN Hong-mei Objective To evaluate occupational exposure risk in workers to anticancer drugs in pharmacy intravenous admixture service (PIVAS) of a hospital，and to further optimize the admixture workflow and management of anticancer drugs in PIVAS. Methods A total of 34 workers in PIVAS of a hospital from March 1 to 25 of 2019 were selected and divided into the exposed group (18 cases) and the control group (16 cases) according to whether they were exposed to antitumor drugs. Wiping samples were collected from the surface of the object in the work environment and personal protective materials，and biological samples were collected from the selected workers. To investigate the level of contamination，environmental and biological effects were monitored with cyclophosphamide (CP) and cytarabine (CAR) as markers. Results Environmental monitoring results suggested that different pollution levels of CP and CAR existed in the surface of different objects in the work environment of PIVAS. The most polluted place was the countertop of biosafety cabinets with CP residual concentration of (3.303±0.701) ng/cm2 and CAR residual concentration of (0.838±0.247) ng/cm2，followed by the doorknobs of deploy rooms with CP residual concentration of （1.629±0.142）ng/cm2 and CAR residual concentration of （0.108±0.026）ng/cm2. Biological monitoring results indicated that the total apoptosis rate of lymphocytes in the exposed group increased compared with the control group with statistical significance (P＜0.05). The positive rate of TA98 and TA100 mutations caused by high-dose urine concentration in the exposed group was higher than that in the control group with statistical significance (P＜0.05). Conclusion Different levels of anticancer drug contamination exist in the work environment of PIVAS，which may cause certain damage to workers. 2020 Vol. 27 (18): 179-182 [Abstract] ( 57 ) HTML (40 KB)  PDF  (0 KB)  ( 9 ) 183 Cause analysis and preventive measures of nursing adverse care events ZENG Xue-qin； HUANG Xiao-mei； SHI Ke-qin； WEN Sheng-ying Objective To analyze and summarize the causes，types and grades of 137 cases of nursing adverse events in our hospital，in order to formulate corresponding preventive measures. Methods A retrospective analysis of 137 cases of nursing adverse events reported in our hospital from January 2017 to December 2018 was made，the type，causes and grades of them were analyzed and discussed. Data processing was used by methods such as percentage and frequency.Results The top three incidences of 137 types of nursing adverse events were: tube slippage (36 cases，26.3%)，medication error in (16 cases，11.7%)，and condition evaluation under (13 cases，9.5%). The level of nursing adverse events was mainly level Ⅲand Ⅳ，and there was no level Ⅰevent. The main reasons included the lack of strict verification system，insufficient evaluation of patients，and lack of health education. Conclusion The causes of adverse care events with high incidence were diversified. Targeted preventive measures for the causes of adverse care events could effectively reduce the incidence of adverse care events and improve the quality of care. 2020 Vol. 27 (18): 183-186 [Abstract] ( 76 ) HTML (39 KB)  PDF  (0 KB)  ( 9 ) 187 Construction of clinical trial data management system in the new situation GUO Zuo-bing； ZAN Ying Standardized clinical trial data collection and management is an important condition for ensuring the quality and level of clinical trials. The existing clinical trial management systems at home and abroad have problems such as poor compatibility，inconvenience in use，and difficulty in promotion. In order to develop a clinical trial data management system that meets the requirements of clinical trial data management，the hospital develops and designs it based on the clinical trial process，introduces the system′s construction design，technical route，and system functions. Meanwhile，the system can retain existing working habits and easy operation； interface with other hospital systems，directly collect data，reduce manual transcription，and avoid the chance of errors； automatically generate eCRF and SRS data packets，multi-plan deployment，easy to popularize. 2020 Vol. 27 (18): 187-190 [Abstract] ( 60 ) HTML (39 KB)  PDF  (0 KB)  ( 8 ) 191 Application effect of "studies on the theoretical and practical issues of party building" in the management of party building work in hospital in the new era CAO Qian Objective To explore the application effect of ＂studies on the theoretical and practical issues of party building＂ in the management of party building work in hospital in the new era. Methods From February to December 2015，the party building work of our hospital was carried out in accordance with conventional methods (before the implementation). From February to December 2016，＂studies on the theoretical and practical issues of party building＂ was carried out (after the implementation). The sense of professional belonging (occupational identity，organizational commitment，occupational satisfaction，willingness to stay) and hospital management scores (management ability，leadership，human and material resources，basic service ability，participation in the daily affairs of the hospital) of medical staff before and after the implementation were evaluated. Results After the implementation，the scores of medical staff′s occupational identity，organizational commitment，occupational satisfaction，willingness to stay were all higher than those before the implementation，and the differences were statistically significant (P＜0.05). After the implementation，the scores of medical staff′s (management ability，leadership，human and material resources，basic service ability，participation in the daily affairs of the hospital were higher than those before the implementation，and the differences were statistically significant (P＜0.05). Conclusion The development of ＂studies on the theoretical and practical issues of party building＂ in the party building work in hospital in the new era is helpful to improve the comprehensive management ability of hospitals，improve the sense of professional belonging of medical staff，enrich the cultural life of hospital staff，and is worth popularizing and applying. 2020 Vol. 27 (18): 191-193转197 [Abstract] ( 48 ) HTML (35 KB)  PDF  (0 KB)  ( 12 ) 194 Application of critical care professional group nursing in patients with chronic obstructive pulmonary disease with respiratory failure BAI Lin-lin； HU Sai-nan Objective To explore the application effect of critical care professional group nursing in patients with chronic obstructive pulmonary disease (COPD) and respiratory failure. Methods A total of 100 cases of COPD patients with respiratory failure admitted to our hospital from July 2017 to June 2019 were selected as the research objects. According to the random number table method，they were divided into the control group (50 cases) and the observation group (50 cases). Patients in the control group were given routine nursing care. Patients in the observation group were given critical care professional group nursing. Blood gas analysis indexes，post-nursing recovery indexes，total complication rate，nursing quality score and overall nursing satisfaction rate were compared between the two groups. Results After nursing，the blood oxygen partial pressure，blood oxygen saturation，pH value，nursing quality score and overall nursing satisfaction rate of patients in the observation group were higher than those in the control group，and the partial pressure of carbon dioxide and the total complication rate were lower than those in the control group，with statistically significant differences (P＜0.05). The duration of mechanical ventilation，ICU stay and hospital stay in the observation group were all shorter than those in the control group，with statistically significant differences (P＜0.05). Conclusion The establishment of critical care professional group has a significant effect on the nursing of patients with COPD and respiratory failure，which can significantly improve the quality of nursing and has a positive effect on the prognosis of patients. 2020 Vol. 27 (18): 194-197 [Abstract] ( 56 ) HTML (35 KB)  PDF  (0 KB)  ( 9 ) 198 Discussion on class teaching reform of Stomatology based on BOPPPS teaching mode GAO Yong-zhi； LI Yan； CHEN Shan-shan； WANG Hui； WANG Jin-shan As an indispensable link of the curriculum education system for medical students，stomatology should be paid sufficient attention to in the education and training of both stomatological and non-stomatological medical students，it occupies a vital position in the development of comprehensive abilities and overall medical viewpoint of medical students. In view of the previous problems occurred in stomatology classroom teaching，such as students′ low learning interest，lack of internal learning motivation，poor team awareness and lack of collaboration ability，the BOPPPS teaching mode is adopted and improved in traditional teaching to deal with the problems in traditional classroom teaching. In this paper，the traditional stomatology classroom teaching mode is reformed through the combination of BOPPPS teaching mode and Internet WeChat platform，a new classroom teaching mode，and the classroom teaching reform of stomatology is studied and discussed，so as to provide reference for the improvement of the teaching effect of stomatology. 2020 Vol. 27 (18): 198-200转204 [Abstract] ( 48 ) HTML (34 KB)  PDF  (0 KB)  ( 11 ) 201 Application of modified mini-clinical evaluation exercise in clinical teaching of orthopedic interns ZHANG Shai-lin； SHANG Pei-yang； PANG Gang； CHEN Teng； SHI Ji-xiang Objective To investigate the feasibility and value of modified mini-clinical evaluation exercise (Mini-CEX)in clinical teaching of orthopedic interns. Methods From August 2018 to July 2019，84 undergraduates of five-year clinical medicine practiced in the Department of Orthopedics，Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine were selected. According to the random number table method，they were divided into control group and observation group，with 42 cases in each group. In the control group，the interns received the traditional teaching method，and the interns in observation group received the modified Mini-CEX teaching method. The results of clinical comprehensive ability assessment and teaching satisfaction rate between the two groups were compared. Results Before the internship，there were no significant differences between the two groups in the assessment results of clinical comprehensive ability (P＞0.05). After the internship，the assessment results of clinical comprehensive ability of the two groups were higher than those before the internship，and the differences were statistically significant (P＜0.05).Moreover，after the internship，students in the observation group scored higher in the assessment of clinical comprehensive ability than the control group，with statistically significant difference (P＜0.05). The total rate of teaching satisfaction in the observation group was higher than that in the control group，the difference was statistically significant (P＜0.05). Conclusion The application of modified Mini-CEX teaching method can effectively enhance the clinical comprehensive ability of orthopedic interns and their satisfaction with clinical teaching，and more suitable for clinical practice teaching in surgical departments. 2020 Vol. 27 (18): 201-204 [Abstract] ( 64 ) HTML (35 KB)  PDF  (0 KB)  ( 6 ) 205 A case report of maculopapules induced by selective serotonin reuptake inhibitors YANG Xue； YANG Li-ying； GONG Zi-min； HE Juan； WANG Xi-jin One young female patient with depressive disorder who developed a similar rash during the treatment of depressive symptoms with the selective serotonin reuptake inhibitors Paroxetine and Sertraline respectively was reported.The mechanism of skin irritation caused by antidepressants，characteristics of drug-induced rashes and skin cross-reactions of selective serotonin reuptake inhibitors were reviewed，so as to improve the awareness of clinicians about skin cross-reactions in the same type of antidepressants. Combined with literature，it is found that the skin cross-reaction between Paroxetin and Sertraline is more common in selective serotonin reuptake inhibitors. In the process of diagnosis and treatment，clinicians should take the patients′ allergy history seriously，and avoid the use of the same type of allergy drugs or similar drugs，to prevent the drug induct-hypersensitivity syndrome. 2020 Vol. 27 (18): 205-208 [Abstract] ( 67 ) HTML (36 KB)  PDF  (0 KB)  ( 12 ) 209 Rescuing a pregnant woman with HELLP syndrome complicated with hepatic subcapsular hematoma and rupture hemorrhagic shock: a case report HUANG Chun-yan； CHENG Qiu-rong； ZHOU Shuang HELLP syndrome is one of the serious complications of severe preeclampsia，complicated with hepatic capsular rupture and hemorrhage，which is a rare critical and severe obstetric disease. The disease changes rapidly and dangerously，which seriously threatens the health of mother and child. Its complex clinical manifestation poses a great challenge for clinical thinking and rapid response ability of clinicians. At present，clinicians have insufficient understanding of this disease，lack of clinical experience，especially in timely treatment and drug selection. However，comprehensive assessment of maternal condition，etiology identification，early diagnosis，timely treatment and multidisciplinary treatment are the keys to reducing the morbidity and mortality of gravida and fetus. This article reports a case of a successful multidisciplinary rescue of a pregnant woman with HELLP syndrome complicated with hepatic rupture and hemorrhagic shock. After admission，this pregnant woman underwent emergency ultrasound examination，quickly started green channel and hepatobiliary surgery to perform cesarean section，together with hepatic artery ligation，hepatic wound compression，hemostasis and ICU rescue after operation. After more than 2 months of multidisciplinary treatment，the patient recovered and was discharged from hospital. Through the comprehensive analysis of the symptoms，physical examination，clinical examination results，medical history，diagnosis and treatment process of the pregnant woman，the purpose is to summarize the treatment experience and lessons，so as to improve the rapid response ability of the obstetrics team，rapid and accurate assessment of disease changes and comprehensive treatment level. 2020 Vol. 27 (18): 209-212 [Abstract] ( 73 ) HTML (37 KB)  PDF  (0 KB)  ( 7 ) 213 Wellens syndrome with severe stenosis of left anterior descending coronary artery and right coronary artery: a case report and literature review LAI Xun-yao HE Li-ya TAN Li This paper reports a case of Wellens syndrome with severe stenosis of left anterior descending coronary artery and right coronary artery. Through consulting the literature，the effective identification and timely treatment of Wellens syndrome with high risk are discussed. Wellens syndrome has characteristic electrocardiogram (ECG) T wave symmetry deep inversion or positive and negative bidirectional change or evolution，and these characteristics of ECG may not be consistent with clinical symptoms，which can easily lead to missed diagnosis and misdiagnosis. The construction of medical association and regional chest pain center，and timely，effective multi-disciplinary cooperation can achieve early diagnosis and timely reperfusion treatment. 2020 Vol. 27 (18): 213-215转219 [Abstract] ( 71 ) HTML (31 KB)  PDF  (0 KB)  ( 6 ) 216 Application effect of Internet+continuous nursing mode combined with peer education in the initial diagnosis of diabetic patients JIA Cai-xia； YU Yuan； WANG Yan Objective To explore the application effect of Internet+continuous nursing mode combined with peer education in newly diagnosed diabetic patients. Methods A total of 68 newly diagnosed diabetic patients who came to our hospital from January 2018 to August 2019 were selected，and they were divided into the combined group and the control group according to the random number table method，34 cases in each group. The control group received routine health education for diabetes mellitus，and the combined group received Internet+continuous nursing mode combined with peer education. The scores of self efficacy scale (DMSES) and quality of life specific scale (DSQL) before and after intervention were observed between the two groups. Results After intervention，the scores of diet and foot care，clinical treatment score，and exercise score in combined group were higher than those in control group，with statistical differences (P＜0.05). The scores of physiological function，psychology/spirit，social relationship and treatment in the combined group after intervention were lower than those in the control group，with statistical differences (P＜0.05). Conclusion Internet+continuous nursing mode combined with peer education can effectively improve self-management efficiency and quality of life of newly diagnosed diabetic patients，which is worth clinical promoting. 2020 Vol. 27 (18): 216-219 [Abstract] ( 43 ) HTML (34 KB)  PDF  (0 KB)  ( 13 ) 220 Application effect of improved nursing intervention in CT-guided puncture of cervical cancer patients ZENG Lan-ying Objective To investigate the application effect of the improved nursing intervention in the CT-guided puncture of cervical cancer patients. Methods A total of 83 patients admitted to our hospital from January 2017 to January 2019 were selected as the research objects. According to the random number table method，they were divided into routine nursing intervention group (n=41) and improved nursing intervention group (n=42). The puncture success rate，puncture status，postoperative complications and total nursing satisfaction were compared between the two groups.Results The initial puncture success in the improved nursing intervention group was 100.00% (42 cases)，which was higher than that in the routine nursing intervention group 92.68% (38 cases)，the difference was statistically significant(P＜0.05). The puncture time (［27.16±4.86］ min) and postoperative bedridden time (［13.64±4.25］ h) of the improved nursing intervention group were shorter than those of the routine nursing intervention group (P＜0.05)，and pain score(［5.09±1.56］ points) was lower than that of the routine nursing intervention group (P＜0.05). Postoperative complications in the improved nursing intervention group included vaginal bleeding (2.38%，1 case)，pain (69.05%，69 cases)，and fever (2.38%，1 case)，all of which were lower than those in the routine nursing intervention group （P＜0.05）. The nursing total satisfaction of the improved nursing intervention group was 97.62%，which was higher than that of the conventional nursing intervention group (73.17%)，the difference was statistically significant (P＜0.05). Conclusion The implementation of improved nursing intervention in CT-guided puncture of cervical cancer patients can improve the success rate of puncture，reduce the incidence of postoperative complications，shorten puncture time and bedridden time，alleviate pain，improve nursing satisfaction，which is worthy of promotion and implementation. 2020 Vol. 27 (18): 220-223 [Abstract] ( 55 ) HTML (38 KB)  PDF  (0 KB)  ( 10 ) 224 Effect of multiple rehabilitation nursing model on patients with tibial plateau fractures YANG Hui-ping; XIE Gui-zhen; YANG Fan Objective To study the clinical effect of multiple rehabilitation nursing model for patients with tibial plateau fractures. Methods A total of 58 patients with tibial plateau fractures treated in our hospital from April 2017 to January 2019 were selected as objects of study. They were divided into control group (n=29) and study group (n=29) by drawing lots. In the control group，routine nursing model was used，and in the study group，multiple rehabilitation nursing model was performed. The mastery of disease rehabilitation knowledge and condition of knee function recovery were compared between the two groups. Results The mastery of disease rehabilitation knowledge in the study group was higher than that of the control group，and the difference was statistically significant (P＜0.05). There was no significant difference in Lysholm or ability of daily living (ADL) score before nursing between the two groups (P＞0.05). The Lysholm and ADL scores in the study group were higher than those of the control group after nursing，and the differences were statistically significant (P＜0.05). Conclusion Multiple rehabilitation nursing model for patients with tibial plateau fractures is conducive to improving their disease cognition and knee joint function，which is worthy of clinical application and promotion. 2020 Vol. 27 (18): 224-226 [Abstract] ( 47 ) HTML (31 KB)  PDF  (0 KB)  ( 8 ) 227 Effect of cognitive behavior intervention on psychological status and nursing satisfaction of patients with acute myocardial infarction after percutaneous coronary intervention WANG Ling; ZHANG Xiao-hong; HAN Xiao-ying; WANG Qin; XU Min-xuan Objective To study the effect of cognitive intervention on the psychological state and nursing satisfaction of patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI). Methods A total of 60 patients with AMI after PCI from July 2018 to July 2019 were selected as research objects. According to the different modes of intervention，the patients were divided into control group (n=30) and observation group (n=30). The control group was given routine nursing methods，the observation group was given cognitive behavioral intervention. The psychological state of the two groups was evaluated using the anxiety scale (HAD-A) and depression scale (HAD-D)，the psychological elasticity scale (CD-RISC) was used to evaluate and compare the psychological elasticity level of the two groups，and the total nursing satisfaction of the two groups was compared. Results The incidence of anxiety and depression in the observation group was lower than that in the control group，and the level of psychological elasticity was better than that in the control group，with statistical differences (P＜0.05)，and the total nursing satisfaction in the observation group was higher than that in the control group，with statistical difference (P＜0.05). Conclusion Cognitive behavior intervention can improve the psychological state and nursing satisfaction of patients with AMI after PCI. 2020 Vol. 27 (18): 227-229 [Abstract] ( 50 ) HTML (31 KB)  PDF  (0 KB)  ( 7 ) 230 Application effect of improved nursing intervention on patients with varicocele after transumbilical single-site laparoscopic surgery WU Cai-ling Objective To explore the application effect of improved nursing intervention on patients with varicocele(VC) performed with transumbilical single-site laparoscopic surgery. Methods A total of 60 patients with VC for surgeries who were admitted to our hospital from July 2017 to July 2018 were selected. They were divided into observation group and control group by simplified randomized method. The conventional nursing was conducted in the control group and the improved nursing was added in the observation group. The total effective rate of nursing，sperm density，effective sperm number，sperm vitality index，wound healing time，hospital stay，and self-rating anxiety scale (SAS) score of the two groups were compared. Results The total effective rate of nursing in the observation group was 93.33%，higher than that of the control group，accounting for 80.00%，the total incidence of complications was 10.00% in the observation group，lower than that of the control group for 26.67%，with statistical differences (P＜0.05). In the observation group，the sperm density was (102.41±11.74)×106/ml，effective sperm number was (43.52±10.02)×106/ml，sperm vitality index was (30.06±1.31)%； in the control group，the sperm density was (83.56±10.31)×106/ml，effective sperm number was (36.89± 0.14)×106/ml，sperm vitality index was (24.65±1.27)%； all indicators in the observation group were higher than those of the control group，with statistical differences (P＜0.05). In the observation group，the wound healing time and hospital stay were (3.38±1.42) d and (4.05±1.26) d. In the control group，the wound healing time and hospital stay were (5.27±2.05) d and (6.89±1.52) d. The wound healing time and hospital stay of the observation group were shorter than those of the control group，with statistical differences (P＜0.05). The SAS score of the observation group was(15.06±2.08) points，and the SAS score of the control group was (29.01±5.14) points. The SAS score of the observation group was lower than that of the control group，with statistical difference (P＜0.05). Conclusion Modified nursing intervention on VC patients after transumbilical single-site laparoscopic surgery can effectively improve the therapeutic effect，accelerate the rehabilitation of patients and alleviate their negative sentiment. It has a satisfactory clinical effect. 2020 Vol. 27 (18): 230-232 [Abstract] ( 45 ) HTML (34 KB)  PDF  (0 KB)  ( 8 ) 233 Effect of whole-course cluster nursing on quality of life and social support ability of patients with metastatic castration-resistant prostate cancer LI Xiao-rong; XU Dan; HU Jin-ling; ZHANG Chun-fen Objective To evaluate the effect of whole-course cluster nursing on the quality of life and the ability to use social support in patients with metastatic castration-resistant prostate cancer. Methods A total of 42 metastatic castration-resistant prostate cancer patients who received chemotherapy in our hospital from January 2018 to February 2019 were selected，they were divided into control group and observation group according to random number table method，21 cases in each group. The control group received routine care，and the observation group received whole-bundle nursing. The ability of using social support，cancer patient quality of life measurement scale (FACT-G) and prostate cancer specific quality of life score (PCS) were compared in both groups. Results There were no significant difference in the objective support utilization scores between the two groups (P＞0.05)； but the scores of subjective and social support utilization in the observation group were higher than those of the control group，the differences were statistically significant (P＜0.05). The scores of FACT-G and PCS after chemotherapy in the two groups were higher than those before chemotherapy，the scores of FACT-G and PCS in the observation group were higher than those in the control group，the differences were statistically significant (P＜0.05). Conclusion Whole-bundle nursing can improve the ability of using social support and quality of life in patients with metastatic castration-resistant prostate cancer chemotherapy. 2020 Vol. 27 (18): 233-235 [Abstract] ( 56 ) HTML (33 KB)  PDF  (0 KB)  ( 10 ) 236 Application of health belief model in self-management of patients undergoing replantation of severed fingers LI Qin-hua； YAN Cheng-fen； YAN Zhuo-yun； LUO Xiao-yan Objective To explore the application value of health belief mode (HBM) in patients′ self-management after replantation of severed fingers. Methods A total of 120 cases of replantation of severed fingers in our hospital from July 2018 to June 2019 were selected，they were divided into control group and observation group by the random number table method，60 cases in each group. The control group was given routine treatment and nursing，and the observation group was given HBM based nursing intervention strategy on the basis of the control group. The health belief score，self-care ability score，the exercise of self-care agency (ESCA)，self-rating anxiety scale (SAS)，self-rating depression scale (SDS)，quality of life score and the recovery of finger function of the two groups were compared before and after the intervention. Results Before intervention，there were no significant differences in the scores of health belief，quality of life，ESCA，SAS and SDS between the two groups (P＞0.05). After intervention，the patients′ health belief score，ESCA，quality of life and the excellent and good rate of finger function recovery in the observation group were higher than those in the control group，and the SAS and SDS scores were lower than those in the control group，the differences were statistically significant (P＜0.05). Conclusion The nursing intervention strategy based on HBM can improve the patients′health belief and self-care ability，improve the patients′ negative psychological mood，promote the recovery of patients′finger function，and improve the patients′ quality of life. 2020 Vol. 27 (18): 236-238转241 [Abstract] ( 50 ) HTML (36 KB)  PDF  (0 KB)  ( 14 ) 239 Application effect of rapid rehabilitation surgery concept in patients with gastric cancer surgery ZHANG Chun-na Objective To analyze the application effect of the concept of rapid rehabilitation surgery (FTS) concept in patients with gastric cancer surgery. Methods A total of 96 patients with gastric cancer who were treated in our hospital from June 2016 to June 2017 were selected as the research subjects. They were divided into control group (n=48)and intervention group (n=48) according to even and odd grouping method. The control group adopted routine nursing mode，the intervention group adopted FTS concept nursing. The total incidence of complications，clinical indicators were compared between the two groups. Results The total incidence of postoperative complications in the intervention group was lower than that in the control group，and the difference was statistically significant (P＜0.05). The intervention group′s operation time，intraoperative blood loss，time to get out of bed，anal exhaust time，and hospital stay were shorter than those in the control group，and the differences were statistically significant (P＜0.05). Conclusion Patients undergoing gastric cancer surgery receiving the concept of FTS can promote smooth operation，reduce postoperative complications，and improve the postoperative recovery effect，which is worthy of promotion and application. 2020 Vol. 27 (18): 239-241 [Abstract] ( 63 ) HTML (28 KB)  PDF  (0 KB)  ( 8 ) 242 Effect of compound heat preservation measures on prevention of hypothermia in elderly patients undergoing electroprostatectomy LIU Chang; LIU Qiu-qiu Objective To investigate the effect of combined heat preservation measures on preventing hypothermia in elderly patients undergoing electroprostatectomy. Methods From February to October 2019，68 elderly patients over 70 years old with benign prostatic hyperplasia (BPH) who underwent electroprostatectomy patients were selected as the research objects，and they were randomly divided into the control group (34 cases) and the observation group (34 cases)according to the matching principle. The control group adopted the conventional thermal insulation measures，and the observation group adopted the composite thermal insulation measures. The nasopharynx temperature at different times(T1 was the temperature when entering the room，T2 was the temperature after anesthesia induction，T3 was the temperature during the operation for 30 minutes，T4 was the temperature during the operation for 60 minutes，and T5 was the temperature after the operation) was compared between the two groups，and the amount of bleeding during the operation，the time of anesthesia recovery，and the incidence of hypothermia of the two groups were observed and recorded.Results There was no significant difference in the body temperature of T1，T2 and T3 between the two groups (P＞0.05).The body temperature of T4 and T5 in the observation group was higher than that of the control group，the difference were statistically significant (P＜0.05). The temperature of T2，T3 and T4 in the observation group was significantly lower than that of T1，the difference were statistically significant (P＜0.05). There was no significant difference in the body temperature between T2 and T1 in the control group (P＞0.05). The body temperature of T3，T4 and T5 in the control group was significantly lower than that of T1，the difference were statistically significant (P＜0.05). The incidence of hypothermia in the observation group was significantly lower than that in the control group，the difference was statistically significant (P＜0.05).The amount of bleeding in the observation group was less than that in the control group，and the recovery time of anesthesia in the observation group was shorter than that in the control group，the difference were statistically significant (P＜0.05). Conclusion In the elderly patients with electroprostatectomy，the effect of application of composite heat preservation nursing measures is significant，which can effectively maintain the normal temperature of patients during the operation，prevent the occurrence of hypothermia，it is worth optimizing. 2020 Vol. 27 (18): 242-245 [Abstract] ( 50 ) HTML (45 KB)  PDF  (0 KB)  ( 8 ) 246 Application effect of the concept of fast track surgery in the nursing of patients undergoing knee arthroplasty LI Zhuo-hui； ZHANG Chun-qiong； LI Ling-xiao Objective To observe the application effect of the concept of fast track surgery (FTS) in the nursing of patients undergoing knee arthroplasty. Methods A total of 90 patients hospitalized in our hospital from August 2017 to August 2019 for the treatment of knee arthroplasty were selected as the research objects，patients were divided into two groups according to random number table method，the control group (n=45) took routine nursing intervention，and the observation group (n=45) took the concept of FTS nursing intervention on the base of the control group. The recovery of knee joint function in the two groups before and 3 weeks after surgery was evaluated by hospital for special surgery knee rating scale (HSS). The joint pain in the two groups before and 3 weeks after surgery was evaluated by visual analogue scale (VAS). The postoperative nursing total satisfaction of two groups was investigated by the nursing satisfaction questionnaire. Results There were no significant differences in HSS and VAS scores between the two groups preoperative (P＞0.05). The HSS score of the two groups 3 weeks after surgery was higher than that before treatment，the difference was statistically significant (P＜0.05)，and the VAS score was lower than before treatment，the difference was statistically significant (P＜0.05). In addition，HSS score of the observation group was higher than of the control group after treatment，VAS score of the observation group was lower than that of the control group，the differences were statistically significant (P＜0.05). The postoperative nursing total satisfaction of the observation group (93.33%) was higher than that of the control group (71.11%)，the difference was statistically significant (P＜0.05). Conclusion The application of FTS in the nursing of knee arthroplasty can significantly improve the patients′ knee joint function，alleviate the knee joint pain，and significantly improve the nursing satisfaction. 2020 Vol. 27 (18): 246-248转252 [Abstract] ( 49 ) HTML (34 KB)  PDF  (0 KB)  ( 10 ) 249 Application effect of comprehensive nursing in patients with stroke and epilepsy FANG Yuan Objective To explore the application effect of comprehensive nursing methods on patients with stroke (CVA)and epilepsy. Methods A total of 100 patients with CVA and epilepsy treated in our hospital from August 2018 to August 2019 were selected and divided into control group and observation group according to the random number table method，50 cases in each group. The control group was given routine nursing care. The observation group applied comprehensive nursing. Self-care ability，motor function，neurological deficit score，total nursing satisfaction and total incidence of complications were compared between two groups. Results The physical function (［47.23±4.55］ points)，psychological function (［68.89±5.57］ points)，social function (［50.23±5.12］ points)，material life score (［66.74±5.53］ points)，and the total score (［79.68±3.45］ points) in the observation group were higher than those of the control group for(35.45±3.76) points，(46.65±4.31) points，(45.65±5.03) points，(43.58±4.48) points，(53.26±3.52) points，the differences were statistically significant (P＜0.05)，the motor function score of patients in the observation group was (67.47±3.45)points，which was higher than that in the control group for (55.56±5.23) points，and the difference was statistically significant (P＜0.05)，the neurological deficit score of the observation group was (15.23±2.32) points，lower than the control group for (18.75±3.31) points，the difference was statistically significant (P＜0.05)，and the nursing total satisfaction of the observation group patients (94.00%) was higher than that of the control group (80.00%)，the difference was statistically significant (P＜0.05). The total incidence of complications in the observation group (4.00%) was lower than that in the control group (18.00%)，the difference was statistically significant (P＜0.05). Conclusion The application of comprehensive nursing methods for patients with CVA and epilepsy can not only effectively improve patients′ motor function and self-care ability，but also reduce their neurological deficits and complications，and it can also promote the relationship between patients and caregivers，increase patients′ satisfaction with nursing work，it is worth clinical applying. 2020 Vol. 27 (18): 249-252 [Abstract] ( 55 ) HTML (36 KB)  PDF  (0 KB)  ( 10 )

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