联合检测宫颈长度及孕妇血清中细胞间黏附分子-1水平对早产的预测

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Abstract Objective To explore the predictive value of cervical length and intercellular adhesion molecule-1 (ICAM-1) in serum of pregnant women. Methods A total of 241 parturients with single pregnancy in our hospital from January 2018 to October 2019 were selected. According to the pregnant state and the gestational age at delivery they were divided into healthy control group (n=90)，threatened preterm delivery group (n=88) and preterm delivery group (n=63).The cervical length and serum ICAM-1 concentration were measured in all the parturients. The above indexes of the three groups were compared to evaluate the predictive value of cervical length and ICAM-1 on preterm delivery. Results the cervical length of preterm delivery group was shorter than that of healthy control group and threatened preterm delivery group，and the serum ICAM-1 level of preterm delivery group was higher than that of the other two groups，with statistical differences (P＜0.05)； the positive rate of cervical length and serum ICAM-1 in preterm delivery group was higher than that of healthy control group (P＜0.05)； the sensitivity and negative predictive value of cervical length combined with serum ICAM-1 were higher than those of single index diagnosis. Conclusion The combination of cervical length and serum ICAM-1 has a high predictive value for the occurrence of preterm delivery in pregnant women，which is worthy of clinical application.

Key words： Cervical length Intercellular adhesion molecule-1 Preterm birth Predictive value

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	Articles by authors
	PENG Jing
	HUANG Ya
	ZHU Li-xian
	ZHONG Jie
	LIANG Yan-qin
	ZHANG Fen
	ZHAO Ming-jie

Cite this article:

PENG Jing,HUANG Ya,ZHU Li-xian, et al. Prediction of preterm birth by combined detection of cervical length and intercellular adhesion molecule-1 in serum of pregnant women[J]. 中国当代医药, 2020, 27(18): 114-116.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I18/114

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