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2020 Vol. 27, No. 1
Published: 2020-01-08
 
 
4 Clinical effect of Qili Qiangxin Capsules modulating Toll-like receptors in the treatment of patients after acute myocardial ischemia and reperfusion
SHAO Liang; ZHANG Ping; CAI Xin-yong; XIAO Bin; MEI Song-bei
Objective To study the value of Qili Qiangxin Capsules modulating Toll-like receptors in improving cardiac function in patients after acute myocardial ischemia (MI) and reperfusion. Methods A total of 100 patients after acute MI and reperfusion treated in the Department of Cardiology in Jiangxi Provincial People′s Hospital from January 2017 to December 2018 were selected as subjects.They were divided into control group and observation group according to the random number table method,50 cases in each group.In the control group,standard therapy was used,while in the observation group,standard treatment combined with Qili Qiangxin Capsules was adopted.The cardiac function indicators like N-terminal pro brain natriuretic peptide (NT-proBNP),left ventricular ejection fraction (LVEF),left ventricular end-systolic diameter (LVESD),left ventricular end-diastolic diameter (LVEDD) and inflammatory factors such as chemokines IP-10 (IP-10),interleukin-8 (IL-8),tumor necrosis factor-α (TNF-α) were compared in the two groups.Results Before treatment,there were no significant differences in LVEF,LVESD,LVEDD,and NT-proBNP between the two groups (P＞0.05).After treatment,LVEF in both groups was higher than that before treatment,LVESD,LVEDD and NT-proBNP in both groups were lower than those before treatment,the differences were statistically significant(P＜0.05).After treatment,the LVEF of the observation group was higher than that of the control group,the LVESD,LVEDD and NT-proBNP of the observation group were lower than those of the control group,the differences were statistically significant (P＜0.05).Before treatment,there were no significant differences in IP-10,IL-8 and TNF-α between the two groups (P＞0.05).After treatment,IP-10,IL-8 and TNF-α in both groups were lower than those before treatment,the differences were statistically significant (P＜0.05).After treatment,the IP-10,IL-8 and TNF-α in the observation group were all lower than those of the control group,the differences were statistically significant (P＜0.05).Conclusion Qili Qiangxin Capsules can inhibit the expression of inflammatory factors by regulating Toll-like receptors,so as to improve the cardiac function of patients after acute MI and reperfusion,which is worthy of promotion.
2020 Vol. 27 (1): 4-7 [Abstract] ( 140 ) HTML (37 KB)  PDF  (0 KB)  ( 5 )
8 Systematic review and Meta-analysis of randomized controlled trials of platelet-rich plasma in the treatment of lateral epicondylosis
HUANG Si-cong; L IU Xue-dong ; LI Chun-ling ; CHEN Yu-fang ; LI Yi-qun▲
Objective To systematically evaluate the efficacy and safety of platelet-rich plasma (PRP) in the treatment of lateral epicondylosis (LE). Methods Computers were searched for Cochrane Library,WanFang Data,CNKI,VIP,PubMed and EMBASE.The time limit was from the establishment of the library to March 31,2019.Randomized controlled trials (RCTs) on PRP for the treatment of LE was found.The exclusion criteria were used to screen the literature,and the literature quality was evaluated.The Meta-analysis was performed using RevMan 5.3 software. Results A total of 461 patients were included in the 7 RCTs.The results of the Meta-analysis showed that in the 1 and 2 months,the steroid group was better than the PRP group in relieving pain and improving upper limb function,and the difference was statistically significant (P＜0.05).There were no significant differences in pain relief and functional improvement between the two groups within 3 months (P＞0.05).After 6 months and 1 year,the effect of PRP group on pain relief and upper extremity function improvement was better than that of steroid group,the difference was statistically significant (P＜0.05). Conclusion The short-term pain relief and functional improvement of steroids is superior to PRP.However,PRP has significant advantages and safety in the long-term pain relief and functional improvement.Due to the limited inclusion of research and the limitations of the literature itself,more high-quality clinical studies need to be further validated in the future.
2020 Vol. 27 (1): 8-12 [Abstract] ( 113 ) HTML (46 KB)  PDF  (0 KB)  ( 9 )
13 Research progress on the correlation between knee osteoarthritis and osteoporosis
ZHANG Chen； CHENG Meng-qi； SONG Guo-rui； LIU Zi-ge ； CHEN De-sheng
Since China entered the age of aging,the number of knee osteoarthritis and osteoporosis patients has increased year by year. These two diseases often appear at the same time and reciprocal causation and cause a vicious cycle,which makes osteoporosis and osteoarthritis of correlation between them is increasingly valued by researchers. So far,the correlation between the two diseases is still unclear,and more and more research results tend to positively correlate osteoarthritis with osteoporosis. This article summarizes the recent research results on the correlation between osteoporosis and knee osteoarthritis,and discusses the correlation between the two diseases from general information,pathogenesis,and treatment methods to guide clinical treatment.
2020 Vol. 27 (1): 13-16转20 [Abstract] ( 110 ) HTML (48 KB)  PDF  (0 KB)  ( 11 )
17 Research progress of miR-182 and proteomics on preterm premature rupture of membrane
BAO Xue ； LU Dan▲
Preterm premature rupture of membrane (PPROM) is one of the common obstetric complications.PPROM is closely related with infection,which has a serious impacts on maternal and infant outcomes.miR-182 is located at the 31-34 site on the long arm of human chromosome 7 and participates in the regulation of important cell functions.Proteomic analysis was devoted to the discovery of potential biomarkers of diseases.The latest advances of miR-182 and proteomics in predicting PPROM combined with chorioamnionitis were reviewed.
2020 Vol. 27 (1): 17-20 [Abstract] ( 104 ) HTML (36 KB)  PDF  (0 KB)  ( 13 )
21 Research progress on the mechanism of Xiaochaihu Decoction in the treatment of cervical vertigo
FANG Jian-qi； SU Li-fang； LIN Jian； LIU Jin-yong； CHEN Xiu-ming； CAI Shu-he
The process of cervical vertigo is relatively long,and the disease of the patients is lingering. It is no longer a simple cold or heat,virtual or real,but a mixture of cold and heat,virtual and real. For such a complex condition,western medicine with neck traction,physical therapy,nutritional nerve and other methods of treatment is not effective.The effect of traditional Chinese medicine is not ideal. Xiaochaihu Decoction in the classical prescription can reconcile exterior and interior,harmonize yin and yang,and coordinate rise and fall,which has a good therapeutic effect on cervical vertigo. This paper will discuss the mechanism of Xiaochaihu Decoction in the treatment of cervical vertigo by combining anatomy,physiology and experiment in modern medicine.
2020 Vol. 27 (1): 21-23转43 [Abstract] ( 107 ) HTML (41 KB)  PDF  (0 KB)  ( 12 )
24 Research progress of the correlation between serum cystatin C,homocysteine and carotid unstable plaque
CHEN Yan； LIU Shuang-xi； TAN Dun-yong； SHU Wen-zhang
Carotid atherosclerotic plaques can be divided into stable plaques and unstable plaques (vulnerable plaques). Cerebral infarction caused by falling off of unstable carotid plaque,especially large atherosclerotic cerebral infarction. At present,the research shows that cystatin C (Cyst-C) and homocysteine (Hcy) may be high risk factors of carotid atherosclerosis,and high levels of Cyst-C and Hcy may be related to the occurrence and development of unstable carotid plaque. To explore the formation mechanism of carotid unstable plaque is beneficial to the diagnosis,treatment and prevention of cerebrovascular events. At present,the correlation between serum Cyst-C,Hcy and carotid unstable plaque is a research hotspot,but there is no unified conclusion. Therefore,the paper reviewed the correlation between serum Cyst-C,Hcy and carotid unstable plaque in recent years.
2020 Vol. 27 (1): 24-27 [Abstract] ( 109 ) HTML (43 KB)  PDF  (0 KB)  ( 13 )
28 Research progress of early enteral nutrition support in patients with severe craniocerebral injury
YE Jing
Severe craniocerebral injury is a common clinical neurosurgery serious disease,mainly due to the violent action of the patients′ head caused craniocerebral tissue damage coma for more than 6 hours,or the patient coma again.The incidence of severe craniocerebral injury is about 13.00%-21.00% of the total incidence of craniocerebral injury,and the mortality is significantly higher than that of ordinary craniocerebral injury.Severe craniocerebral injury is likely to cause severe damage to the patients′ neurological function and pose a serious threat to the patients′ physical and mental health,quality of life and quality of life.A large number of clinical studies have shown that patients with severe craniocerebral injury are in a state of high energy consumption and high catabolism,and the body energy consumption has increased significantly.By implementing early enteral nutrition,the body′s energy needs can be replenished in time,which can help improve the body′s immunity and avoid infection.However,after early enteral nutrition support treatment,various serious complications are prone to occur,such as gastrointestinal bleeding,hyperglycemia,etc,which will seriously affect the prognosis of the disease and even increase the risk of death.Therefore,the key to improving the prognosis of patients with severe head injury is to strengthen early enteral nutrition nursing intervention.This article reviews the research progress of early enteral nutrition support for patients with severe head injury,in order to provide clinical basis.
2020 Vol. 27 (1): 28-30 [Abstract] ( 97 ) HTML (33 KB)  PDF  (0 KB)  ( 5 )
31 Clinical effect of Valsartan combined with Amlodipine in the treatment of hypertension
LUO Xiang-wei
Objective To investigate the clinical effect of Valsartan combined with Amlodipine in the treatment of hypertension.Methods Ninety-eight patients with hypertension who were treated in our hospital from May 2018 to April 2019 were selected as the subjects.They were divided into the control group and observation group by random number table method,with 49 cases in each group.The two groups were given conventional symptomatic treatment.The control group was treated with Amlodipine.The observation group was treated with Valsartan combined with Amlodipine on the basis of conventional symptomatic treatment.The total treatment effective rate,systolic blood pressure and diastolic blood pressure,the total incidence of adverse reactions were compared between the two groups.Results The total treatment effective rate of the observation group was higher than that of the control group,and the difference was statistically significant (P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups (P＞0.05).There was no significant difference in systolic and diastolic blood pressure between the two groups before treatment (P＞0.05).After treatment,the systolic and diastolic blood pressures of the two groups were lower than those before treatment,and the systolic and diastolic blood pressure of the observation group were lower than those of the control group,the differences were statistically significant (P＜0.05).Conclusion In the clinical treatment of hypertension,Valsartan combined with Amlodipine is effective and safe,and it can be smoothly reduced,which is worth further promotion and application.
2020 Vol. 27 (1): 31-33 [Abstract] ( 113 ) HTML (32 KB)  PDF  (0 KB)  ( 10 )
34 Effect of Rosuvastatin on inflammatory factors and blood lipid levels in patients with unstable angina pectoris
REN Zhi-chao; SONG Zhan-chun; ZHANG Di ; ZHANG Si-yuan ; LIN Xiao
Objective To investigate the effect of Rosuvastatin on inflammatory factors and short-term prognosis in patients with unstable angina pectoris (UAP).Methods From November 2018 to April 2019,80 patients with UAP treated in our hospital were selected and randomly divided into experimental group (n=40) and control group (n=40).The experimental group was given Rosuvastatin 10 mg/time,once a day,while the control group was given Atorvastatin 20 mg/time,once a day.The levels of serum lipids,levels of high sensitivity C-reactive protein (hs-CRP),interleukin-12 (IL-12)and interleukin-23 (IL-23) were measured before treatment and 4 weeks after treatment.Results Before treatment,The total cholesterol (TC),triglyceride (TG),low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C),hs-CRP,IL-12 and IL-23 levels of two groups had no significant difference (P＜0.05).Four weeks after treatment,the levels of TC,TG,LDL-C,hs-CRP,IL-12 and IL-23 in the two groups were lower than those before treatment,and the differences were statistically significant (P＜0.05).The level of HDL-C in the control group was higher than that before treatment,and the difference was statistically significant (P＜0.05).Four weeks of after treatment,the levels of TC,TG,hs-CRP and IL-12 in the experimental group were lower than those in the control group,the differences were statistically significant (P＜0.05).Conclusion Rosuvastatin has more significant effect in improving blood lipid and inflammatory factors in patients with UAP,which is worthy of clinical application.
2020 Vol. 27 (1): 34-36 [Abstract] ( 105 ) HTML (32 KB)  PDF  (0 KB)  ( 9 )
37 Clinical effect of emergency clustering regimen in the treatment of acute heart failure
LU Zhu-biao ; LAI Run-kang

Objective To investigate the clinical effect of emergency clustering regimen in the treatment of acute heart failure (AHF).Methods Sixty patients with AHF treated in our hospital from January 2017 to January 2019 were selected.According to the random number table method,the patients were divided into routine treatment group (n=30)and emergency cluster treatment group (n=30).The routine treatment group was treated with conventional regimen,and the emergency cluster treatment group was provided with conventional regimen+emergency clustering regimen.The effects of treating,shortness of breath symptom relief time,total time of emergency treatment,hospital stay were compared; acute physiology and chronic health (APACHE) Ⅱscores,hypersensitive C-reactive protein (hs-CRP),left ventricular ejection fraction,arterial blood oxygen saturation,respiration rate mortality rate were compared between the two groups before and after treatment.Results The curative effect of the emergency cluster treatment group was higher than that of the routine treatment,the difference was statistically significant (P＜0.05).The time of shortage of breath relief,the total time of emergency treatment,and the hospital stay were shorted than those of the routine treatment,the differences were statistically significant (P＜0.05).The APACHEⅡscore,hs-CRP,and respiration rate of the emergency cluster treatment group were lower than those of the conventional treatment group,the left ventricular ejection fraction and arterial oxygen saturation were higher than those of the conventional treatment group,with statistical significances(P＜0.05).There was no significant difference in mortality between the two groups (P＞0.05).Conclusion The conventional regimen+emergency clustering regimen is effective in treating AHF,which can improve patients′ vital signs and cardiac function,accelerate recovery and shorten treatment.
2020 Vol. 27 (1): 37-39 [Abstract] ( 95 ) HTML (31 KB)  PDF  (0 KB)  ( 14 )
40 Clinical effect of Atorvastatin Calcium combined with Ezeimaibu in the treatment of coronary heart disease
NI Cheng-zhi; TANG Li-dong
Objective To explore the clinical effect of Atorvastatin Calcium combined with Ezeimaibu in the treatment of coronary heart disease.Methods From May 2016 to March 2019,160 patients with coronary heart disease treated in our hospital were selected as the subjects,and divided into control group and experimental group according to random number table method,with 80 cases in each group.The patients of the two groups were treated with routine coronary heart disease,on the basis of routine treatment,patients in the control group were given Atorvastatin Calcium Tablets for intensive treatment,while patients in the experimental group were treated with Ezetimib Tablets on the basis of the treatment plan of the control group.Both groups were treated for 4 weeks.The clinical treatment effects of the two groups were compared.The indexes of cardiac function (left ventricular ejection fraction [LVEF],left ventricular enddiastolic diameter [LVDD],creatine kinase isoenzyme [CK-MB],cardiac troponin I [cTnI],blood lipid before and after treatment and adverse reactions were compared between the two groups.Results The total effective rate of the experimental group was higher than that of the control group,and the difference was statistically significant (P＜0.05).After treatment,the high density lipoprotein cholesterol (HDL-C) of the experimental group was higher than that of the control group,and the low density lipoprotein cholesterol (LDL-C),total cholesterol (TC) and triglyceride (TG) of the experimental group were higher than those of the control group,and the differences were statistically significant (P＜0.05).The levels of LVEF and cTnI in the experimental group were higher than those in the control group,the differences were statistically significant (P＜0.05).The LVDD and CK-MB in the experimental group were lower than those in the control group,and the differences were statistically significant (P＜0.05).The total incidence of adverse reactions in the experimental group was lower than that in the control group,and the difference was statistically significant (P＜0.05).Conclusion Compared with the intensive treatment with Atorvastatin Calcium alone,Atorvastatin Calcium combined with Ezetimibe Tablets has a significant effect on coronary heart disease.It can promote the improvement of cardiac function and blood lipid metabolism in patients with coronary heart disease.It is safe and worthy of clinical application.
2020 Vol. 27 (1): 40-43 [Abstract] ( 119 ) HTML (36 KB)  PDF  (0 KB)  ( 12 )
44 Effect of Ginkgolide Injection on platelet activation in patients with acute cerebral infarction
WU Qiong; LIN Shao-hua; FU Ying
Objective To investigate the effect of Ginkgolide Injection on platelet activation in patients with acute cerebral infarction (ACI).Methods A total of 112 patients with ACI treated in the Second Affiliated Hospital of Nanchang University from January 2016 to January 2018 were selected as the study subjects for retrospictive analysis.According to the different treatment methods,they were divided into the control group and the treatment group,56 cases in each group.The control group was treated with Aspirin and the treatment group was treated with Ginkgolide Injection.The levels of platelet membrane glycoprotein (PAC-1) and cluster of differentiation 62 platelet (CD62P) were compared between the two groups before and after treatment.The main adverse cardiovascular and cerebrovascular events in the two groups were analyzed.Results The total effective rate of the treatment group was 96.43%,which was higher than that of the control group (80.36%),the difference was statistically significant (P＜0.05).Before treatment,there were no significant differences in PAC-1 and CD62P levels between the two groups (P＞0.05); after treatment,the levels of PAC-1 and CD62P in the two groups were lower than those before treatment,and the levels of PAC-1 and CD62P in the treatment group were lower than those in the control group,the differences were statistically significant (P＜0.05).The total incidence of major adverse cardiovascular events in the treatment group was 3.57%,which was lower than that in the control group (14.29%),the difference was statistically significant (P＜0.05).Conclusion Ginkgolides Injection can significantly improve the clinical efficacy of ACI patients,improve platelet activation,effectively prevent thrombosis and reduce the major adverse cardiovascular events.
2020 Vol. 27 (1): 44-46 [Abstract] ( 98 ) HTML (32 KB)  PDF  (0 KB)  ( 13 )
47 Effect of endovascular interventional embolization for the treatment of cerebral aneurysm rupture
CHEN Xu; ZHANG Yong-an; GONG Shao-hui; ZHAN Jian▲
Objective To investigate the effect of endovascular interventional embolization for the treatment of cerebral aneurysm rupture.Methods A total of 100 patients with cerebral aneurysm rupture treated in the Department of Neurosurgery in the Shangrao People′s Hospital from August 10,2015 to August 10,2016 were selected as the study subjects.They were divided into two groups by drawing lots,50 cases in each groups.In the observation group,patients were treated with endovascular interventional embolization,while in the control group,patients were treated with conventional method.The therapeutic effect,operative time,hospital stay,intraoperative blood loss,and total incidence of complications were compared between the two groups.Results The total effectiveness rate of the observation group was 98.00%,which was higher than that of the control group (72.00%),with statistically significant difference (P＜0.05).The operation time and hospital stay of the observation group were (45.21±1.02) min and (5.21±1.32) d,which were shorter than those of the control group for(77.13±1.32)min and(11.26±1.97)d,the intraoperative blood loss was(254.13±1.23) ml in the observation group,which was less than that in the control group for (365.25±1.97) ml,the differences were statistically significant (P＜0.05).The total incidence of complications in the observation group was 2.00%,which was lower than that in the control group accounting for 24.00%,with statistically significant difference (P ＜0.05).Conclusion The effect of endovascular interventional embolization for the treatment of cerebral aneurysm rupture is remarkable with few complications,which can significantly shorten the operation time and hospital stay and is worthy of study.
2020 Vol. 27 (1): 47-49 [Abstract] ( 59 ) HTML (51 KB)  PDF  (0 KB)  ( 7 )
47 Effect of endovascular interventional embolization for the treatment of cerebral aneurysm rupture
CHEN Xu; ZHANG Yong-an; GONG Shao-hui; ZHAN Jian
Objective To investigate the effect of endovascular interventional embolization for the treatment of cerebral aneurysm rupture.Methods A total of 100 patients with cerebral aneurysm rupture treated in the Department of Neurosurgery in the Shangrao People′s Hospital from August 10,2015 to August 10,2016 were selected as the study subjects.They were divided into two groups by drawing lots,50 cases in each groups.In the observation group,patients were treated with endovascular interventional embolization,while in the control group,patients were treated with conventional method.The therapeutic effect,operative time,hospital stay,intraoperative blood loss,and total incidence of complications were compared between the two groups.Results The total effectiveness rate of the observation group was 98.00%,which was higher than that of the control group (72.00%),with statistically significant difference (P＜0.05).The operation time and hospital stay of the observation group were (45.21±1.02) min and (5.21±1.32) d,which were shorter than those of the control group for(77.13±1.32)min and(11.26±1.97)d,the intraoperative blood loss was(254.13±1.23) ml in the observation group,which was less than that in the control group for (365.25±1.97) ml,the differences were statistically significant (P＜0.05).The total incidence of complications in the observation group was 2.00%,which was lower than that in the control group accounting for 24.00%,with statistically significant difference (P ＜0.05).Conclusion The effect of endovascular interventional embolization for the treatment of cerebral aneurysm rupture is remarkable with few complications,which can significantly shorten the operation time and hospital stay and is worthy of study.
2020 Vol. 27 (1): 47-49 [Abstract] ( 87 ) HTML (51 KB)  PDF  (0 KB)  ( 11 )
50 Application effect of home exercise training with App based on mobile Internet technology in patients with Parkinson′s disease
LIU Yan-ping1,2； HUANG Zu-cheng1,2 ； MA Qi-shou1,2 ； FU Wei-wei1,2 ； HOU Cui-lan1,2
Objective To investigate the application effect of home exercise training with App based on mobile Internet technologyin patients with Parkinson′s disease (PD).Methods A total of 30 patients with PD treated in our hospital from June 2017 to August 2018 were selected as the subjects,and divided into control group and research group by random number table method,with 15 cases in each group.The control group accepted home exercise training with the help of pamphlet,while the research group was given home exercise training by using App.The patients of the two groups were assessed by using the united Parkinson′s disease rating scale Ⅱ(UPDRS Ⅱ)and UPDRS Ⅲ,Berg balance scale(BBS),and time up and go test (TUGT) before and after 8 weeks of training.Results After training,the UPDRS Ⅱand UPDRS Ⅲscores in the research group were lower than those before training,and the differences were statistically significant (P＜0.05).There were no significant differences in UPDRS Ⅱand UPDRS Ⅲscores of the control group before and after training (P＞0.05).The UPDRS Ⅱand UPDRS Ⅲscores in the research group were lower than those in the control group,and the differences were statistically significant (P＜0.05).After training,the BBS scores in the both groups were higher than those before training,and the differences were statistically significant (P＜0.05).The BBS score in the research group was higher than that in the control group,and the difference was statistically significant (P＜0.05).After training,the TUGT in the research group was shorter than that before training,and and the difference was statistically significant(P＜0.05).There was no significant difference in TUGT of the control group before and after training (P＞0.05).The TUGT in the research group was shorter than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion The application of home rehabilitation training App could improve PD patients′ motor function and activity of daily life,which can be promoted in clinic,but further research is needed to optimize it.
2020 Vol. 27 (1): 50-52转56 [Abstract] ( 105 ) HTML (36 KB)  PDF  (0 KB)  ( 11 )
53 Application effect of minimal invasion of cranial aspiration and drainage in older adult patients with hypertension intracerebral hemorrhage
WU Shi-qiang； LUO An-lin； FANG Ting； GUAN Hui-dong； LI Wen-tian
Objective To investigate the effect of minimal invasion of cranial aspiration and drainage in older adult patients with hypertension intracerebral hemorrhage (HICC).Methods One hundred older adult patients with HICC in our hospital from August 2016 to December 2018 were selected as subjects.The patients were divided into the control group (n=50) and the study group (n=50) by the random number table method.Patients in the control group underwent craniotomy evacuation of hematoma,and in the study group,minimal invasion of cranial aspiration and drainage was used.The clinical effect,the National Institutes of Health stroke scale (NIHSS) score before and after surgery,the activity of daily living index (BI) before and after surgery,and the incidence of complications were compared between the two groups.Results The total therapeutic effectiveness rate in the study group was 92.00%,which was higher than that in the control group accounting for 72.00%,the difference was statistically significant (P＜0.05).There were no differences in the preoperative NIHSS score or preoperative BI score between the two groups (P＞0.05).After surgery,the NIHSS score was(12.02±2.03) points in the study group,which was lower than that in the control group for (15.10±2.85) points,the difference was statistically significant (P＜0.05).The BI score was (74.35±6.15) points in the study group,which was higher than that in the control group for (66.10±6.75) points,the difference was statistically significant (P＜0.05).The total incidence of complications in the study group was 4.00%,lower than that of the control group accounting for 16.00%,with statistical significance (P＜0.05).Conclusion The treatment of HICC older adult patients performed with minimal invasion of cranial aspiration and drainage can obtain a remarkable effect.This is worthy of clinical application.
2020 Vol. 27 (1): 53-56 [Abstract] ( 104 ) HTML (35 KB)  PDF  (0 KB)  ( 9 )
57
Effect of Danhong Injection and Naoxintong Capsules on serum hypersensitive C-reactive protein and blood lipid in patients with acute cerebral infarction
 
Effect of Danhong Injection and Naoxintong Capsules on serum hypersensitive C-reactive protein and blood lipid in patients with acute cerebral infarction
 
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Objective To explore the clinical effect of Danhong Injection combined with Naoxintong Capsules in the treatment of acute cerebral infarction.Methods A total of 160 patients with acute cerebral infarction admitted to our hospital from December 2017 to December 2018 were selected as the subjects,and divided into study group and control group,with 80 cases in each group.The control group was treated with conventional Western medicine.The study group was treated with Danhong Injection and Naoxintong Capsules on the basis of conventional Western medicine.The tumor necrosis factor-α (TNF-α),hypersensitive C-reactive protein (hs-CRP),and blood lipid levels of the patients were compared between the two groups.Results There were no significant differences in TNF-α and hs-CRP between the two groups before treatment (P＞0.05).The tumor necrosis factor-α (TNF-α) and hypersensitive hs-CRP in the study group were lower than those in the control group after treatment,and the differences were statistically significant (P＜0.05).The TNF-α and hs-CRP levels in the two groups after treatment were lower than those before treatment (P＜0.05).There were no significant differences in the levels of triglyceride (TG),total cholesterol (TC),low-density lipoprotein (LDL-C) and high-density lipoprotein (HDL-C) between the two groups before treatment (P＞0.05).After treatment,the TG and TC in the study group were lower than those in the control group,and the differences were statistically significant (P＜0.05).The TG,TC and LDL-C after treatment in the two groups were lower than those before treatment,and the differences were statistically significant (P＜0.05).Conclusion Danhong Injection combined with Naoxintong Capsules can reduce serum hs-CRP,TG and TC levels,inhibit inflammation and improve blood lipid levels in patients with acute cerebral infarction.
2020 Vol. 27 (1): 57-59 [Abstract] ( 73 ) HTML (31 KB)  PDF  (0 KB)  ( 10 )
60 Clinical effect of Eszopiclone in the treatment of insomnia
OU Hai-yan； YE Xiu-er； GAN Xiao-wen； HE Wan-ting
Objective To investigate the clinical effect of Eszopiclone in the treatment of insomnia.Methods A total of 80 insomniacs treated in the outpatient department of our hospital from October 2017 to April 2019 were selected as the subjects,and divided into the control group and observation group by random number table method,with 40 cases in each group.The control group was treated with Astazolam Tablets,and the observation group was treated with Eszopiclone.The clinical efficacy,Pittsburgh sleep quality index (PSQI) changes,sleep status questionnaire (SRSS) scores and incidence of adverse reactions of the two groups were compared.Results The total effective rate of the observation group was 87.50%,compared with 82.05% of the control group,the difference was not statistically significant (P＞0.05).The scores of sleep time,sleep time,sleep disorder,sleep quality,sleep efficiency,sleep drugs,daytime function and total scores of PSQI in the observation group were lower than those in the control group,the differences were statistically significant (P＜0.05).The SRSS scores of the observation group at 2 and 4 weeks after treatment were lower than those of the control group,and the differences were statistically significant (P＜0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion Eszopiclone is effective in the treatment of insomnia,and can effectively improve the quality of sleep,and the incidence of adverse reactions is lower,which has positive clinical significance.
2020 Vol. 27 (1): 60-62 [Abstract] ( 109 ) HTML (35 KB)  PDF  (0 KB)  ( 9 )
63 Clinical effect of Alprostadil Injection in the treatment of acute cerebral infarction
LIANG Xian-sheng; XU Yi-fan; LI Zong-hong
Objective To explore the clinical effect of Alprostadil Injection in the treatment of acute cerebral infarction.Methods A total of 100 patients with acute cerebral infarction admitted to our hospital from January 2018 to January 2019 were selected as the study objects,they were divided into the observation group and the control group according to random number table method,with 50 cases in each group.The control group treated with basic method,and the observation group treated with Alprostadil Injection on the basis of the control group.USA national institutes of health stroke scale (NIHSS) score,modified Rankin scale before stroke (mRS) score and laboratory indexes were compared before and after treatment between the two groups.The total incidence of adverse reactions were compared between the two groups.Results The NIHSS and mRS scores of the observation group were lower than those of the control group on the 15th,30th and 90th days after treatment,the differences were statistically significant (P＜0.05).The platelet aggregation rate,plasma factor Ⅷrelated antigen and tissue plasminogen activator inhibitor level in the observation group were lower than those in the control group on the 15th day after treatment,and the tissue plasminogen activator level was higher than that in the control group,the differences were statistically significant (P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups (P＞0.05).Conclusion Alprostadil Injection can effectively improve the brain nerve function and laboratory indexes of patients with acute cerebral infarction,and does not increase the incidence of adverse reactions,which is worth clinical application.
2020 Vol. 27 (1): 63-66 [Abstract] ( 87 ) HTML (36 KB)  PDF  (0 KB)  ( 11 )
67 Application effect comparison of the thromboelastography and traditional coagulation function in patients with craniocerebral injury
MAI Jian-pei
Objective To analyze the application effect of thromboelastography and traditional coagulation function in patients with craniocerebral injury.Methods Forty-six patients with craniocerebral injury who underwent surgery in our hospital from January to December 2018 were selected as the subjects.The patients were divided into control group and observation group according to different coagulation function monitoring methods during operation,with 23 cases in each group.The patients in the control group underwent traditional coagulation function monitoring.The patients in the observation group underwent thromboelastography monitoring.The operation time,blood loss,infusion volume and other operation indexes and postoperative status were compared between the two groups.Results There were no significant differences in the operation time and urine volume between the two groups (P＞0.05).The amount of bleeding,infusion volume,suspended red blood cell transfusion,fresh frozen plasma infusion,cryoprecipitate infusion,and platelet transfusion in the observation group were less than those in the control group,and the differences were statistically significant(P＜0.05).The drainage volume at 6 and 24 h after operation in the observation group were less than those in the control group,and the differences were statistically significant (P＜0.05).Conclusion Patients with craniocerebral injury undergo thromboembolic examination during surgical treatment,which can accurately judge the coagulation function of patients and reduce the infusion of blood products,which is of great significance for the treatment of patients.
2020 Vol. 27 (1): 67-69 [Abstract] ( 83 ) HTML (32 KB)  PDF  (0 KB)  ( 14 )
70 Clinical effect of different doses of Venlafaxine combined with Agomelatine in the treatment of refractory depression
JI Er-ni; ZHU Lian; CAI Lu-yao
DOI: 文拉法辛；阿戈美拉汀；难治性抑郁症；疗效
Objective To investigate the clinical effect of different doses of Venlafaxine and Agomelatine in the treatment of refractory depression.Methods A total of 82 patients with refractory depression who were admitted to the Department of Affective Disorders in Kangning Hospital of Shenzhen City from April 2016 to March 2018 were selected as study subjects.The patients were divided into observation group and control group,with 41 cases in each group.Patients in both groups were treated with Agomelatine Tablets after 1 week of drug washing.On this basis,patients in the control group were treated with Venlafaxine at 75-150 mg/d,while patients in the observation group were treated with Venlafaxine at 150-300 mg/d.After 7 weeks of treatment,the efficacy and incidence of adverse reactions such as headache,palpitations,dizziness,nausea,drowsiness and constipation were compared between the two groups.Results After treatment,the total effective rate of the observation group was 92.68%,which was higher than that of the control group (65.85%),the difference was statistically significant (P＜0.05).The total incidence of adverse reactions such as headache,palpitations,dizziness,nausea,lethargy,and constipation in the observation group was 14.64%,compared with the control group (12.20%),the difference was not statistically significant (P＞0.05).Conclusion According to the patients′ treatment,the dose of Venlafaxine is controlled in the range of 150-300 mg/d during the treatment,and the dose is increased as much as possible.In combination with Agomelatine in the treatment of refractory depression,the curative effect is remarkable,and the drug risk of adverse reactions is not increased,with high therapeutic safety，which is worthy of clinical application.
2020 Vol. 27 (1): 70-72 [Abstract] ( 100 ) HTML (32 KB)  PDF  (0 KB)  ( 15 )
73 Effect of Cerebroprotein Hydrolysate Injection combined with Sodium Valproate on epilepsy seizures after craniocerebral trauma
ZHANG Xiao-qiang ; ZHOU Hui; HUANG Xiao-long
Objective To investigate the clinical effect of Cerebroprotein Hydrolysate Injection combined with Sodium Valproate in the prevention and treatment of epilepsy seizures after craniocerebral trauma.Methods A total of 439 patients with craniocerebral trauma admitted to our hospital from October 2016 to October 2018 were selected as research objects.According to the time of admission,the patients were divided into treatment group (220 cases) and control group (219 cases).The treatment group was given Cerebroprotein Hydrolysate Injection and Sodium Valproate after admission.The control group was treated with Cerebroprotein Hydrolysate Injection only.After one month of treatment,the total incidence of epilepsy and adverse reactions were compared between the two groups.Results The total incidence of epilepsy in the treatment group was 9.55%,which was lower than that in the control group (21.46%),the difference was statistically significant (P ＜0.05).The total incidence of adverse reactions in the treatment group was 5.00%,which was lower than that in the control group (10.50%),and the difference was statistically significant (P＜0.05).Conclusion Cerebroprotein Hydrolysate Injection combined with Sodium Valproate has a good prevention and treatment effect on epilepsy seizures after craniocerebral trauma,which is worthy of clinical promotion.
2020 Vol. 27 (1): 73-75 [Abstract] ( 84 ) HTML (32 KB)  PDF  (0 KB)  ( 14 )
76 Effect of Rosuvastatin on blood lipid,inflammatory factors and carotid atherosclerotic plaque in patients with cerebral infarction
TANG Pei-lan; WU Da-hua; XIE Le; FAN Jian-hu
Objective To investigate the effect of Rosuvastatin on blood lipid,inflammatory factors and carotid atherosclerotic plaque in patients with cerebral infarction.Methods A total of 80 patients with acute cerebral infarction and carotid atherosclerotic plaque treated in our hospital from January 2017 to April 2018 were selected as the study objects,and divided into the observation group and control group by the random number table method,with 40 cases in each group.The observation group used Rosuvastatin,and the control group used Atorvastatin.The changes of blood lipid indexes and inflammatory factors between the two groups were compared,and the incidence of carotid plaque hemorrhage and plaque fibrous cap rupture were compared.Results The levels of lipid-related total cholesterol,triglyceride and low density lipoprotein the observation group were lower than those in the control group,and the level of high density lipoprotein was higher than that in the control group,the differences were statistically significant (P＜0.05).Three months after treatment,the levels of inflammatory factors such as hypersensitive C-reactiveprotein (hs-CRP) and interleukin-6 (IL-6) in the observation group were lower than those in the control group,and the differences were statistically significant (P＜0.05).One-year follow-up,the incidence rates of internal hemorrhage of carotid plaque and rupture of plaque fibrous cap in the observation group were lower than those in the control group,and the differences were statistically significant (P＜0.05).Conclusion For acute cerebral infarction,Rosuvastatin is an ideal lipidregulating agent,which can reduce the level of inflammatory response and reduce the incidence of plaque lesions.
2020 Vol. 27 (1): 76-78 [Abstract] ( 98 ) HTML (34 KB)  PDF  (0 KB)  ( 14 )
79 Application effect of Butylphthalide Soft Capsules in patients with ischemic cerebrovascular disease
CHENG Shi-hong
Objective To investigate the application effect of Butylphthalide Soft Capsules in patients with ischemic cerebrovascular disease.Methods Sixty patients with ischemic cerebrovascular disease in our hospital from February 2017 to January 2019 were selected as the research objects,they were divided into control group (30 cases) and observation group (30 cases) according to the odd even grouping method.The control group was treated with conventional western medicine,and the observation group was treated with Butylphthalide Soft Capsules on the basis of the control group.The clinical effect of the two groups were compared.The USA national institutes of health stroke scale (NIHSS)score,Barthel index (BI),the number of circulating endothelial progenitor cells,the number of migrating cells and the level of inflammatory factors of the two groups were compared before and after treatment.Results The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant (P＜0.05).After treatment,NIHSS score of the observation group was lower than that of the control group,BI was higher than that of the control group,the differences were statistically significant (P＜0.05).After treatment,the number of circulating endothelial progenitor cells and migration cells in the observation group were higher than those in the control group,the levels of IL-6 and hs-CRP were lower than those in the control group,the differences were statistically significant (P＜0.05).Conclusion It can effectively improve the neurological function,improve the quality of life and reduce the level of inflammatory factors,which is worthy of clinical application.
2020 Vol. 27 (1): 79-81 [Abstract] ( 88 ) HTML (31 KB)  PDF  (0 KB)  ( 14 )
82 Clinical effect of repetitive transcranial magnetic stimulation in the treatment of dysphagia after stroke
DING Chang-yu； ZOU Sa-feng； WANG Xiao-feng
Objective To study the clinical effect of repetitive transcranial magnetic stimulation in the treatment of dysphagia after stroke.Methods From January 2016 to March 2019,160 patients with dysphagia after stroke with a course of 30-90 days treated in our hospital were selected and randomly divided into treatment group (80 cases) and control group (80 cases) according to the treatment order.Both groups were given swallowing dysfunction training,and the treatment group was given repetitive transcranial stimulation on this basis.The treatment cycle was 4 weeks.Swallowing function was evaluated by Watian drinking water test before and after treatment.The Watian water drinking test scores and the total effective rate of treatment were compared between the two groups.Results There was no significant difference between the two groups in the score of Watian drinking water test before treatment (P＞0.05).After treatment,the Watian water drinking test scores of the two groups of patients were lower than those before treatment,and the differences were statistically significant (P＜0.05).The Watian water drinking test score of the patients in the treatment group after treatment was lower than that in the control group,and the difference was statistically significant (P＜0.05).The total effective rate of the treatment group was higher than that of the control group,and the difference was statistically significant (P＜0.05).Conclusion Repetitive transcranial magnetic stimulation can significantly improve swallowing dysfunction after stroke.
2020 Vol. 27 (1): 82-84转87 [Abstract] ( 86 ) HTML (33 KB)  PDF  (0 KB)  ( 11 )
85 Application effect of comprehensive language rehabilitation training on aphasia after cerebrovascular disease
CHEN Xiao-yan ； WANG Yu-long
Objective To explore the application effect of comprehensive language rehabilitation training on aphasia after cerebrovascular disease.Methods A total of 100 patients with aphasia after cerebrovascular disease admitted to our hospital from December 2016 to March 2018 were selected as the research objects,they were divided into control group and study group by random number table method,50 cases in each group.The control group was treated with routine therapy such as improving circulation and nutrition nerve,the study group was given comprehensive language rehabilitation training on the basis of the above treatment.The total effective rate and language function score of the two groups were compared.Results The total effective rate of the study group was higher than that of the control group,the difference was statistically significant (P＜0.05).There was no significant difference language function score before treatment between the two groups (P＞0.05).The score of language function in the study group was higher than that in the control group,the difference was statistically significant (P＜0.05).Conclusion On the basis of improving the treatment of circulation and nutrition nerves,adding comprehensive language rehabilitation training can significantly improve the treatment effect and language function of patients,which is worthy of clinical application.
2020 Vol. 27 (1): 85-87 [Abstract] ( 87 ) HTML (31 KB)  PDF  (0 KB)  ( 9 )
88 Surgical treatment of ureteral terminal (lower segment) calculi with ureteroscopy under the surface anesthesia of the lumen
TAN Fang-yun; LI Tong; LIU Fan
Objective To investigate the surgical treatment of ureteral terminal (lower segment) calculi with ureteroscopy under the surface anesthesia of the lumen.Methods A total of 48 patients who underwent ureteroscopy for ureteral terminal (lower segment) calculi from June 2017 to May 2019 in our hospital were enrolled as subjects,they were randomly divided into the observation group and control group,with 24 cases in each group.In the observation group,surface anesthesia of the lumen was adopted,while in the control group,combined spinal-epidural anesthesia was used.The operation time,visual analogue scale (VAS) score,lithotripsy success rate,length of hospitalization,hospitalization cost and complications were compared between the two groups.Results The operation time of the observation group was shorter than that of the control group,the difference was statistically significant (P＜0.05).There were no significant differences in VAS score and gravel success rate between the two groups (P＞0.05).The length of hospitalization in the observation group was shorter than that in the control group,and the hospitalization cost was lower than that in the control group,with statistically significant differences (P＜0.05).The total complication rate in the observation group was lower than that in the control group,and the difference was statistically significant (P＜0.05).Conclusion Ureteroscopy under the surface anesthesia of the lumen for ureteral terminal (lower segment) calculi can shorten the operation time and length of hospitalization,reduce the economic burden of patients,and decrease the rate of anesthesia complications.It is a safe,effective and economical anesthetization,and is worthy of promotion in clinical practice.
2020 Vol. 27 (1): 88-90 [Abstract] ( 57 ) HTML (33 KB)  PDF  (0 KB)  ( 9 )
91 Clinical effect of high-flux hemodialysis in the treatment of uremia
LI Ting-ting
Objective To observe the clinical effect of high-flux hemodialysis in the treatment of uremia.Methods A total of 118 patients with uremia admitted to our hospital from December 2016 to February 2019 were enrolled in the study.According to the random sampling method,they were divided into reference group (59 cases) and study group(59 cases).Patients in the reference group were treated with conventional hemodialysis,and patients in the study group were treated with high-flux hemodialysis.The total effective rate of treatment and renal function indexes (C-reactive protein,triacylglycerol,creatinine,urine microprotein,urea nitrogen),and immunoglobulin (IgA,IgM,IgG) levels of the two groups before and after treatment were compared.Results The total effective rate of treatment in the study group was 93.22%,which was higher than 64.41% in the reference group,and the difference was statistically significant (P＜0.05).There were no significant differences in the levels of renal function indexes before treatment between the two groups (P＞0.05).After treatment,the levels of renal function indexes of the two groups were lower than those before treatment,and the differences were statistically significant (P＜0.05).The levels of renal function indexes of patients in the study group after treatment were lower than those in the reference group,and the differences were statistically significant (P＜0.05).There were no significant difference in the immunoglobulin levels before treatment between the two groups (P＞0.05).After treatment,the levels of immunoglobulin of the two groups were higher than those before treatment,and the differences were statistically significant (P＜0.05).The levels of immunoglobulin of patients in the study group after treatment were higher than those in the reference group,and the differences were statistically significant (P＜0.05).Conclusion The effect of high-flux hemodialysis in the treatment of uremia patients is better than that of conventional hemodialysis,and the clinical symptoms are significantly improved.
2020 Vol. 27 (1): 91-93转98 [Abstract] ( 71 ) HTML (33 KB)  PDF  (0 KB)  ( 14 )
94 Effect of holmium laser under ureteroscope in the treatment of ureteral calculi
YIN Zheng-guo； CHEN Hai-jian； LI Jin
Objective To investigate the clinical effect and safety of holmium laser under ureteroscope in the treatment of ureteral calculi.Methods A total of 443 cases of patients with ureteral calculi admitted to our hospital from September 2013 to December 2018 were selected as the research subjects,and they were divided into the control group (222 cases) and the observation group (221 cases) according to different treatment methods.The control group was treated with extracorporeal shock wave lithotripsy (ESWL)，while the observation group was treated with holmium laser under ureteroscope.The success rate of single lithotripsy,the rate of calculi excretion within 3 weeks and the incidence of serious complications were compared between the two groups.Results The success rate of single lithotripsy in the observation group was 97.28% (215/221),which was higher than that in the control group accounting for 75.23% (167/222),and the difference was statistically significant (P＜0.05).The rate of calculi excretion within 3 weeks in the observation group was 100.00% (221/221),which was higher than that in the control group accounting for 83.33% (185/222),and the difference was statistically significant (P＜0.05).The total incidence rate of serious complications in the observation group was lower than that in the control group,and the difference was statistically significant (P＜0.05).Conclusion Holmium laser under ureteroscope is a safe and effective method in the treatment of ureteral calculi.It has the advantages of high success rate of single lithotripsy,high rate of the calculi excretion within 3 weeks,fewer serious complications,less trauma and quick postoperative recovery,which is worthy of promotion.
2020 Vol. 27 (1): 94-98 [Abstract] ( 76 ) HTML (44 KB)  PDF  (0 KB)  ( 15 )
99 Comparison of the effects of Cyclophosphamide and Tacrolimus in the treatment of male nephrotic syndrome
WU Yu； SUN Xiao-mei
Objective To investigate the effect of Cyclophosphamide and Tacrolimus in the treatment of male nephrotic syndrome.Methods Seventy male patients with nephrotic syndrome admitted to our hospital from February 2017 to December 2018 were selected as subjects,they were divided into group A and group B according to the random number table method,with 35 cases in each group.Group A was given hormone combined with Tacrolimus,and group B was given hormone combined with Cyclophosphamide.Both groups were treated for 3 months,serum albumin levels,24 h urine protein ration and serum sex hormone levels were compared between the two groups before and 3 months after treatment.Results After 3 months of treatment,the 24 hour urine protein ration of group A was lower than that of group B,the serum albumin level was higher than that in group B,the differences were statistically significant (P＜0.05).Before treatment,there were no significant differences between the two groups in hormone levels (P＞0.05).At 3 months after treatment,the levels of estradiol (E2) and testosterone (T) in the two groups were lower than those before treatment,with statistically significant differences (P＜0.05).At 3 months after treatment,follicle-stimulating hormone (FSH) and luteinizing levels in group A were higher than those before treatment,with statistically significant differences (P＜0.05).At 3 months after treatment,E2 and T levels in group A were higher than those in group B,while FSH level was lower than that in group B,with statistically significant differences (P＜0.05).Conclusion Compared with Cyclophosphamide,Tacrolimus combined with hormone therapy has better curative effect on male nephrotic syndrome,and has less influence on serum sex hormones,which is suitable for clinical application.
2020 Vol. 27 (1): 99-101 [Abstract] ( 103 ) HTML (33 KB)  PDF  (0 KB)  ( 11 )
102 Experimental study of 3D printed navigation template in assisting accuracy of atlantoaxial pedicle screw placement
WU Bing-hua; XU Cong; DENG Gao-rong; GAO Xiang; MIAO Xin; LING Qiang; DONG Cai-rong; ZHANG Kui-zhong
Objective To explore the accuracy of 3D printing navigation template in assisting atlantoaxial pedicle screw placement.Methods From September 2017 to June 2018,10 adult cervical spine specimens were provided by the department of anatomy in Medical College of Nanchang University were selected as subjects.The three dimension digital model of cervical vertebrae was reconstructed by Mimics after CT scanning in 10 cases of adult cervical vertebrae without lesion.The specific reverse template of atlantoaxial vertebrae was designed by 3-matic and the navigation module of atlantoaxial was printed out in 3D.A total of 40 pedicle screws were placed with navigation template,and then the specimens were scanned by CT,reconstructed by Mimics,and dissected to evaluate the accuracy of pedicle screw placement.Results A total of 40 screws inserted with this guide plate were reconstructed by CT scan,Mimics reconstruction and anatomical confirmation of the specimen.One of the screws pierced the pedicle bone cortex.The correct rate of pedicle placement was 97.5%.Conclusion The accuracy of atlantoaxial pedicle screw placement assisted by 3D printing navigation template is high,which is worthy of further clinical study and application.
2020 Vol. 27 (1): 102-104 [Abstract] ( 59 ) HTML (30 KB)  PDF  (0 KB)  ( 15 )
105 Effect of percutaneous vertebroplasty combined with paravertebral in the treatment of osteoporotic vertebral compression fracture
LU Zhi-you; ZHONG Wei-jian; GUO Hui-hong; LI Shun-ping
Objective To explore the effect of percutaneous vertebroplasty (PVP) combined with paravertebral in the treatment of osteoporotic vertebral compression fracture.Methods A total of 128 cases of osteoporotic vertebral compression fractures from January 2016 to April 2018 in our hospital were selected as research objects.According to the patients′ odd or even hospitalization numbers,they were divided into observation group and control group,64 patients in observation group (even hospitalization number ) used percutaneous vertebroplasty combined with paravertebral,and 64 patients in control group (odd hospitalization number) used PVP alone.The total effective rate,operation time and visual analogue scale (VAS) score were compared between the two groups.Results The total effective rate of the observation group was 96.9%,which of the control group was 93.8%,the difference between the two groups was not statistically significant (P＞0.05).The operation time of the observation group was (30.0±2.2) min,which of the control group was(28.0±3.1) min,the difference in operation time between the two groups was not statistically significant (P＞0.05).The VAS scores of the two groups after treatment were lower than those before treatment (P＜0.05),and the VAS score of the observation group was lower than that of the control group after treatment,the difference was statistically significant (P＜0.05).Conclusion PVP combined with paravertebral in the treatment of osteoporotic vertebral can reduce the pentients′pain and improve their quality of lives,the clinical effect is more remarkable without increasing the operation time.
2020 Vol. 27 (1): 105-108 [Abstract] ( 72 ) HTML (39 KB)  PDF  (0 KB)  ( 9 )
109 Clinical effect of internal fixation with hollow screw and mini-plate in the treatment of massive ankle fracture
HUANG Qi-zhi； LI Jun-hao； ZHANG Shuai ； SUN Xiao-dong； SU Fang-gui； YU Peng
Objective To explore the clinical effect of internal fixation with hollow screw and mini-plate in the treatment of massive ankle fracture.Methods A total of 77 patients with massive posterior ankle fracture admitted to our hospital from March 2016 to March 2018 were selected as the research objects.According to the even and odd number of the patient′s admission bed,they were divided into the control group (38 cases) and the observation group (39 cases).The patients in the control group were treated with hollow screw internal fixation,while those in the observation group were treated with mini-plate internal fixation.The intraoperative and postoperative conditions of the two groups were compared.All the patients were followed up for one year to evaluate the fracture complete healing time,complete weight bearing time and ankle joint function.Results The intraoperative blood loss of patients in observation group was less than that in the control group,the difference was statistically significant (P＜0.05).There were no significant difference between the two groups in operation time and total postoperative complication rate (P＞0.05).The fracture healing time and full load completely time in observation group were shorter than those in the control group,the differences were statistically significant (P＜0.05).The treatment excellent rate and American orthopedic foot and ankle society(AOFAS) score in the observation group were higher than those in the control group,with statistically significant differences (P＜0.05).Conclusion Both internal fixation with hollow screw and mini-plate have definite therapeutic effects on massive fracture,but mini-plate internal fixation treatment can decrease the intraoperative blood loss,accelerate fracture healing,improve ankle function,with great application promotion value.
2020 Vol. 27 (1): 109-111 [Abstract] ( 71 ) HTML (33 KB)  PDF  (0 KB)  ( 13 )
112 Effect of percutaneous balloon kyphoplasty at different operation timing on lumbar spine function and complications in patients with osteoporotic compression fracture
MA Le
Objective To investigate the effect of percutaneous balloon kyphoplasty (PKP) on lumbar function and complications in patients with osteoporotic compression fractures.Methods The clinical data of 86 patients with osteoporotic compression fractures admitted to our hospital from March 2016 to March 2018 were retrospective analyzed.The patients were divided into group A and group B according to the different operation timing,43 cases in each group.Group A underwent PKP within 1 week after fracture,while group B underwent PKP within 1-2 weeks after fracture.The visual analogue scale (VAS),lumbar function and complications were compared between the two groups.Results The VAS and Oswestry lumbar dysfunction index (ODI) scores of group A were (1.06±0.43) and (10.25±2.17) points,respectively,which were lower than those of group B for (1.57±0.36) and (16.41±1.84) points,the differences were statistically significant (P＜0.05); the total incidence of complications in group A was 4.65% (2/43),which was lower than 18.60% (8/43) in group B,the difference was statistically significant (P＜0.05).Conclusion PKP treatment in patients with osteoporotic compression fractures as early as possible can effectively reduce postoperative pain,improve lumbar function and reduce the incidence of complications.
2020 Vol. 27 (1): 112-114 [Abstract] ( 74 ) HTML (30 KB)  PDF  (0 KB)  ( 13 )
115 Clinical effect of Bushen Tongluo method combined with Alendronate Sodium in the treatment of ankylosing spondylitis with osteoporosis
CHEN Nian
Objective To explore the clinical effect of Bushen Tongluo method combined with Alendronate Sodium in the treatment of ankylosing spondylitis with osteoporosis.Methods Eighty patients with ankylosing spondylitis (AS) and osteoporosis (OP) admitted to our hospital from August 2017 to June 2018 were selected and divided into the control group (40 cases) and the intervention group (40 cases) according to the random number table method.The control group was treated with Alendronate Sodium.The intervention group was treated combined with Bushen Tongluo method.The bone mineral density (BMD) of the lumbar vertebrae (L2-4),femoral neck and greater trochanter before and after treatment,bone-carboxyglutamate protein (BGP),procollagen type Ⅰamino-terminal prolonging peptide (PⅠNP),carboxyterminal telopeptide of type Ⅰcollagen (CTX) content were compared between the two groups,and the total clinical effectiveness after treatment was observed.Results After treatment,the BMD of L2-4,femoral neck and greater trochanter were higher than those before treatment.The BGP and PⅠNP levels of the two groups were higher than those before treatment,and the CTX level was lower than that before treatment.The BMD of L2-4,femoral neck and greater trochanter of the intervention group were higher than those of the control group.The BGP and PⅠNP levels in the intervention group were higher than those in the control group,and the CTX level was lower than that in the control group,the differences were statistically significant (P＜0.05).The total effective rate of the intervention group was 92.50%,which was higher than that of the control group (75.00%),and the difference was statistically significant (P＜0.05).Conclusion The combination of Bushen Tongluo method and Alendronate Sodiumin in the treatment of patients with AS and OP can significantly improve clinical efficacy and improve bone metabolism and BMD.
2020 Vol. 27 (1): 115-117转120 [Abstract] ( 75 ) HTML (33 KB)  PDF  (0 KB)  ( 12 )
118 Comparison of clinical effects of arthroscopic microfracture and conventional joint debridement in the treatment of knee joint cartilage injury
LIU Zi-qing ； XU Mao-sen； ZHOU Guan-he
Objective To compare the effects of arthroscopic microfracture and conventional joint debridement in the treatment of knee joint cartilage injury.Methods From April 2018 to April 2019,60 patients with knee joint cartilage injuries treated in our hospital were enrolled as the research objects.By tossing the two-color ball,they were equally divided into the control group and observation group.In the control group,routine arthroscopic debridement was used,while in the observation group,arthroscopic microfracture treatment was adopted.The knee joint function score,motor function score and total therapeutic effectiveness rate were compared.Results After operation,the scores of knee joint function and knee joint function of motion of the two groups were higher than those before operation,the differences were statitically significant (P＜0.05).The total effectiveness rate of the observation group was higher than that of the control group,and the difference was statistically significant (P＜0.05).Conclusion The use of arthroscopic microfracture in the treatment of knee joint cartilage injury can markedly improve the knee joint function and motor function recovery,which is worthy of promotion in clinical practice.
2020 Vol. 27 (1): 118-120 [Abstract] ( 77 ) HTML (29 KB)  PDF  (0 KB)  ( 10 )
121 Application effect of comprehensive limb salvage treatment in diabetic foot patients
WU Zhi-chang； MO Jie-hua
Objective To explore the application effect of comprehensive limb salvage treatment in diabetic foot patients.Methods A total of 100 patients with diabetic foot treated in our hospital from July 23,2017 to July 23,2018 were selected as subjects.They were randomly divided into observation group and control group according to the database,with 50 cases in each group.The observation group was treated with comprehensive limb salvage,and the control group was treated with basic therapy.The limb salvage rate,complication rate,knee amputation,toe rate,total effective rate of treatment,wound healing time,granulation tissue growth time,wound reduction area,visual analogue scale (VAS) score and ulcer area were compared between the two groups.Results The limb salvage rate and total effective rate of the observation group were higher than those of the control group,and the differences were statistically significant (P＜0.05).The complication rate and VAS score of the observation group were lower than those of the control group,and the differences were statistically significant (P＜0.05).The area of ulcer in the observation group was smaller than that in the control group,and the difference was statistically significant (P＜0.05).The time of wound healing and granulation tissue growth in the observation group were shorter than those in the control group,and the differences were statistically significant (P＜0.05).Conclusion The effect of comprehensive limb salvage treatment in diabetic foot patients is significant,which can improve the limb salvage rate and shorten the wound healing time.
2020 Vol. 27 (1): 121-123 [Abstract] ( 84 ) HTML (33 KB)  PDF  (0 KB)  ( 11 )
124 Ultrasonic quantitative evaluation of postpartum pelvic floor structural changes and rehabilitation therapy effect
CHEN Hui-ying1 XU Hong-yan； ZHONG Yong-hong； HUANG Xiao-ying； HE Jian-fen； ZHOU Xin-wei
Objective To investigate the changes of pelvic floor structure in postpartum women through the perineal ultrasound,evaluate the effect of rehabilitation therapy,and provide an intuitive and reliable imaging basis for the prevention and treatment of pelvic floor dysfunction caused by delivery.Methods From January 2013 to December 2015,60 primiparas who underwent natural delivery in our hospital were selected as the experimental group,the experimental group was randomly divided into the rehabilitation treatment group (30 cases) and the conventional treatment group (30 cases),and 30 asymptomatic and nulliparous women at the same time were selected as the control group.The rehabilitation treatment group received a course of pelvic floor muscle training,and the conventional treatment group received routine education and natural recovery.The perineal ultrasound was examined at rest and tension,respectively.Ultrasound data were obtained for the experimental group at 6 and 14 weeks after delivery and nulliparous women: bladder neck position (BN),cervical position (CX),and rectal ampulla position (RA),length of the muscular part of the ani levator muscle plane (LAL),to calculate the displacement of the bladder neck,cervix,rectum ampulla from rest period to tension period (bladder neck descent [BND],cervical descent [CXD],rectal ampulla descent [RAD]) and levator ani strain rate (LAS).Results The BND,CXD and LAS of the experimental group were higher than those of the control group,and the differences were statistically significant(P＜0.05).There was no significant difference in RAD between the control group and the experimental group (P＞0.05).The BND,CXD and LAS in the rehabilitation treatment group were lower than those in the conventional treatment group,and the differences were statistically significant (P＜0.05).There was no significant difference in RAD between the rehabilitation treatment group and the conventional treatment group (P＞0.05).Conclusion Pregnancy and delivery may lead to increased mobility of the anterior and middle chamber,represented by the bladder neck and cervix,and LAS,no significant changes in posterior chamber mobility.Pelvic floor rehabilitation treatment has significant effect on postpartum pelvic floor recovery.
2020 Vol. 27 (1): 124-127 [Abstract] ( 75 ) HTML (39 KB)  PDF  (0 KB)  ( 8 )
128 Effect of premature rupture of fetal membranes in full term on delivery mode and maternal and child outcomes
ZHOU Zhao-lian； XIONG Yuan-huan
Objective To investigate the effect of premature rupture of membranes in full term on delivery mode and maternal and child outcomes,so as to provide basis for perinatal health care and prevention of complications.Methods A total of 370 pregnant women with premature rupture of membranes in full term in the Department of Obstetrics and Gynecology,Jiangxi Provincial People′s Hospital from January 2016 to January 2019 were enrolled as the observation group.The other 370 pregnant women without premature rupture of membranes were randomly selected during the same period as the control group.The delivery methods,chorionitis,puerperal disease rate and neonatal asphyxia incidence were compared between the two groups.Results The cesarean section rate in the observation group (47.6%) was higher than that in the control group (28.6%),and the difference was statistically significant (P＜0.05).The incidence rates of chorionitis,puerperal diseases and neonatal asphyxia in the observation group (28.1%,9.5%,8.9%) were higher than those in the control group (7.0%,1.6%,3.0%),and the differences were statistically significant (P＜0.05).Conclusion Compared with the pregnant women without preterm premature rupture of membranes in full term,the cesarean section rate of the pregnant women with preterm premature rupture of membranes in full term is increased,and the incidence of maternal and infant complications is also increased.It is suggested that perinatal health care should strengthen management in terms of prevention and treatment of vaginitis,reduction of drug abuse,balanced nutrition,and reduction of sexual life in the third trimester of pregnancy.At the same time,pregnant women with preterm premature rupture of membranes in full term should terminate pregnancy in time and strengthen prevention and treatment of infection to reduce maternal and infant complications.
2020 Vol. 27 (1): 128-130转134 [Abstract] ( 76 ) HTML (34 KB)  PDF  (0 KB)  ( 11 )
131 Application effect of medical nutrition intervention in early pregnancy on pregnant women with high blood glucose risk
KONG Guan-mei； DENG Yu ； LIN Jin； HUANG Wei； CHEN Li-juan
Objective To explore the application effect of medical nutrition intervention in early pregnancy on pregnant women with high blood glucose risk.Methods From October 2016 to October 2017,80 pregnant women with high blood glucose risk admitted to our hospital were selected as the research objects for retrospective analysis.They were divided into study group and control group according to different intervention methods,with 40 cases in each group.Pregnant women in the control group received routine intervention,while pregnant women in the study group received medical nutrition intervention in early pregnancy.The glycosylated hemoglobin (HbA1c),fasting blood glucose (FPG),2 h postprandial blood glucose (2 h PG) levels before and after the intervention were compared between the two groups of pregnant women,as well as the occurrence of pregnancy complications and adverse neonatal outcomes.Results Before the intervention,there were no significant difference in HbA1c,FPG and 2 h PG levels between the two groups (P＜0.05).After the intervention,the HbA1c level of pregnant women in the study group was lower than that before the intervention,and the FPG and 2 h PG levels of pregnant women in the two groups were lower than those before the intervention.The HbA1c,FPG and 2 h PG levels of pregnant women in the study group were lower than those in the control group,the differences were statistically significant (P＜0.05).The HbA1c level of pregnant women in the control group after intervention was not significantly different from that before intervention (P＞0.05).There was no significant difference in the incidence of polyhydramnios between the two groups (P＞0.05).The incidence rates of gestational diabetes mellitus,cesarean section,premature delivery,postpartum hemorrhage and pregnancy hypertension in the study group were lower than those in the control group,with statistically significant difference (P＜0.05).The total incidence of adverse neonatal outcomes in the study group was lower than that in the control group,and the difference was statistically significant (P＜0.05).Conclusion Medical nutrition intervention for pregnant women with high blood glucose risk in early pregnancy can effectively control blood sugar and reduce the incidence of complications during pregnancy,which is worthy of application and promotion.
2020 Vol. 27 (1): 131-134 [Abstract] ( 66 ) HTML (35 KB)  PDF  (0 KB)  ( 15 )
135 Application effect comparison between abdominal wall transverse incision and longitudinal incision in cesarean section for parturient with scar uterus
HAO Xiu-ping
Objective To investigate the application effect of abdominal wall transverse incision and longitudinal incision in cesarean section for parturients with scar uterus.Methods A total of 50 cases of cicatricial uterus parturients who gave birth in our hospital from August 2010 to October 2017 were analyzed retrospectively.They were divided into observation group (10 cases) and control group (40 cases) according to the different direction of cesarean section.The observation group adopted abdominal wall longitudinal incision while the control group adopted abdominal wall transverse incision.The operation related indexes,pelvic adhesion and incision healing of the two groups were compared.Results The observation group′s maternal operation time,fetal delivery time and postoperative anal exhaust time were shorter than those of the control group,and the intraoperative blood loss was less than that of the control group,with statistically significant differences (P＜0.05).The incidence of pelvic adhesion in the observation group was lower than that in the control group,and the excellent rate of incision healing was higher than that in the control group,the differences were statistically significant (P＜0.05).Conclusion The effect of abdominal wall longitudinal incision in cesarean scar uterus parturient is better than that of transverse incision,which is more conducive to the wound healing of parturient and the reduction of pelvic adhesion rate,and the operation time,fetal delivery time and postoperative anal exhaust time are shorter,intraoperative blood loss is less,which is worthy of clinical application.
2020 Vol. 27 (1): 135-137 [Abstract] ( 79 ) HTML (30 KB)  PDF  (0 KB)  ( 13 )
138 Comparison of maternal and infant outcomes of cervical balloon and Oxytocin induced labor
WANG Wan-qin
Objective To explore the maternal and infant outcomes of cervical balloon and Oxytocin induced labor.Methods Two hundred expectant mothers who needed induced labor during January 2018 to March 2019 in our hospital were selected as the research objects and divided into observation group and control group according to computer random grouping method,with 100 cases in each group.The observation group was induced by cervical balloon and the control group by Oxytocin.The effective rate of cervical ripening,Bishop scores and maternal and infant outcomes were compared between the two groups.Results The total effective rate of cervical ripening and Bishop score in the observation group were higher than those in the control group,the differences were statistically significant (P＜0.05).The rates of cesarean section,laceration of birth canal,postpartum hemorrhage and neonatal asphyxia in the observation group were lower than those in the control group,and the differences were statistically significant (P＜0.05).There was no significant difference in the incidence of fetal translocation between the two groups (P＞0.05).Conclusion Compared with Oxytocin induced labor,cervical balloon induced labor can better promote cervical ripening,improve cervical Bishop score,and improve maternal and infant outcomes in expectant mothers who need induced labor,which is worthy of clinical application and promotion.
2020 Vol. 27 (1): 138-140 [Abstract] ( 89 ) HTML (33 KB)  PDF  (0 KB)  ( 9 )
141 Clinical effect of Terbutaline in adjuvant treatment of childhood asthma
HU Xin
Objective To explore the clinical value of Terbutaline in adjuvant treatment of childhood asthma.Methods A total of 102 children with asthma admitted to our hospital from January 2018 to December 2018 were enrolled and divided into the observation group (n=51) and the control group (n=51) by the random comprehensive balancing method.The control group received routine treatment after admission,while the observation group received Terbutaline sulfate as adjuvant treatment on the basis of the control group.The total effective rate of treatment,adverse reactions (hand tremor,gastrointestinal disorders,headache),nighttime and daytime wheezing frequency,percentage maximum expiratory flow to normal predicted value (PEF%) and percentage volume of expiratory volume in the first second of maximum expiratory flow to predicted value(FEV1%)were compared between the two groups.Results The total effective rate of the observation group was 96.1%,higher than 81.3% of the control group,and the difference was statistically significant(P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups (P＞0.05).The daytime and nighttime wheezing times in the observation group were less than those in the control group,and PEF% and FEV1% were higher than those in the control group,the differences were statistically significant (P＜0.05).Conclusion The addition of Terbutaline to children with asthma on the basis of conventional treatment has obvious therapeutic effect,and Terbutaline will not increase the incidence of adverse reactions,which is worthy of clinical application and promotion.
2020 Vol. 27 (1): 141-143 [Abstract] ( 71 ) HTML (35 KB)  PDF  (0 KB)  ( 11 )
144 Clinical effect of hysteroscopic planing system in the treatment of submucous myoma of uterus
HUA Wen
Objective To investigate the clinical effect of hysteroscopic planing system in the treatment of submucous myoma of uterus.Methods From December 2017 to April 2019,80 cases of uterine submucosal myoma patients admitted to our hospital were selected as the research objects.According to the random number table method,they were divided into control group and research group,40 cases in each group.Patients in the control group were treated with laparoscopic electrosurgical excision procedure,while patients in the research group were treated with hysteroscopic planing system.The intraoperative blood loss,operation time,hospitalization time,anal exhaust time,adverse reactions and postoperative recovery of 1 month were compared between the two groups.Results There were no significant difference between the two groups in intraoperative blood loss and operation time (P＞0.05).The hospitalization time and anal exhaust time of the patients in the research group were shorter than those in the control group,the differences were statistically significant (P＜0.05).The total incidence of postoperative adverse reactions in the research group was lower than that in the control group,and the difference was statistically significant (P＜0.05).One month after the operation,there was no significant difference between the two groups in the excellent and good surgical rate (P＞0.05).Conclusion Using hysteroscope planing system to treat patients with submucous myoma of uterus can not only shorten hospitalization time and anal exhaust time,but also effectively reduce the incidence of adverse reactions,which is worthy of wide clinical application.
2020 Vol. 27 (1): 144-146 [Abstract] ( 81 ) HTML (32 KB)  PDF  (0 KB)  ( 11 )
147 Clinical effect of Mifepristone combined with Methotrexate in the treatment of ectopic pregnancy
LIANG Wei-yan
Objective To investigate the clinical effect of Mifepristone combined with Methotrexate in the treatment of ectopic pregnancy.Methods Forty patients with ectopic pregnancy admitted to our hospital from February 2016 to July 2018 were selected as the research objects,and were divided into control group (20 cases) and observation group (20 cases) according to the difference of single and double hospital bed tail numbers after admission.The patients in the control group were treated with Methotrexate alone,while the patients in the observation group were treated with Mifepristone on the basis of the drugs used in the control group.The clinical therapeutic effect,adverse reactions,serum β-human chorionic gonadotropin (β-HCG) level and the time required to fall to the normal range were compared between the two groups.Results The effective rate of treatment in the observation group was 90.00%,higher than that in the control group (40.00%),and the difference was statistically significant (P＜0.05).The total incidence of adverse reactions in the observation group was 5.00%,lower than that in the control group (30.00%),and the difference was statistically significant (P＜0.05).The serum β-HCG levels before treatment were compared between the two groups,and the difference was not statistically significant (P＞0.05).The level of serum β-HCG in the observation group was lower than that in the control group,and the difference was statistically significant (P＜0.05).The time required to reduce β-HCG to the normal range in the observation group was shorter than that in the control group,and the difference was statistically significant (P＜0.05).Conclusion Compared with Methotrexate alone,Mifepristone combined with Methotrexate has a better effect on ectopic pregnancy with lower incidence of adverse reactions.It can reduce the serum β-HCG level of patients faster and shorten the treatment time,which is worthy of clinical application and promotion.
2020 Vol. 27 (1): 147-149 [Abstract] ( 77 ) HTML (32 KB)  PDF  (0 KB)  ( 12 )
150 Comparison of clinical effect between hysteroscopic curettage and traditional curettage in the treatment of abnormal uterine bleeding
LIU Ping
Objective To investigate the clinical effect of hysteroscopic curettage and traditional curettage in the treatment of abnormal uterine bleeding.Methods A total of 97 patients with abnormal uterine bleeding admitted to our hospital from March 2018 to February 2019 were divided into control group (n=45) and experimental group (n=52) according to different treatment order.Patients in the control group were treated with traditional curettage,while patients in the experimental group were treated with hysteroscopic curettage.The total effective rate of clinical treatment,operation time,intraoperative blood loss,total hospitalization time,menstrual recovery time,complications and recurrence were observed and compared.Results The total effective rate of clinical treatment in the experimental group was higher than that in the control group,the operation time was longer than that in the control group,the menstrual recovery time was shorter than that in the control group,the complication rate and recurrence rate were lower than those of the control group,and the differences were statistically significant (P＜0.05).The intraoperative blood loss and total hospitalization time of the two groups were not statistically significant (P＞0.05).Conclusion Compared with traditional curettage,hysteroscopic curettage has significant clinical effect on the treatment of abnormal uterine bleeding,which can not only improve the total effective rate of clinical treatment,reduce the incidence of adverse reactions and recurrence rate,but also shorten the menstrual recovery time,and is worthy of application and promotion.
2020 Vol. 27 (1): 150-152转156 [Abstract] ( 82 ) HTML (34 KB)  PDF  (0 KB)  ( 13 )
153 Influence of electroencephalograph biofeedback therapy combined with rehabilitation training on motor function and brain function in children with spastic cerebral palsy
TAO Kang
Objective To explore the influence of electroencephalograph (EEG) biofeedback therapy combined with rehabilitation training on motor function and brain function in children with spastic cerebral palsy.Methods Sixty-six children with spastic cerebral palsy who were admitted to our hospital from November 2016 to December 2017 were enrolled as subjects,they were divided into experimental group and control group by random number table method,with 33 cases in each group.The control group received rehabilitation training,the experimental group performed EEG biofeedback therapy on the basis of control group.Balance function,spasticity,intelligence and motor function (standing and walking function of D and E functional areas) were compared between the two groups before and after 3 months of treatment.Results There were no significant differences in the Berg balance scale (BBS) and comprehensive sputum scale (CSS) scores between the two groups before treatment (P＞0.05).After 3 months of treatment,the BBS scores of the two groups were higher than those before treatment,and the CSS scores were lower than before treatment,the differences were statistically significant (P＜0.05).After 3 months of treatment,the BBS score of the experimental group was higher than that of the control group,and the CSS score was lower than that of the control group,with statistically significant differences (P＜0.05).There was no significant difference in the intelligence score between the two groups before intervention (P＞0.05).After 3 months of treatment,the intelligence scores of the two groups were higher than those before treatment,and the differences were statistically significant (P＜0.05),the intelligence score of the experimental group was higher than that of the control group,the differences were statistically significant (P ＜0.05).Before treatment,there were no significant differences in standing and walking function scores of D and E functional areas between the two groups (P＞0.05).After 3 months of treatment,the standing and walking function scores of D and E functional areas of the two groups were higher than those before treatment,and the standing and walking function scores of D and E functional areas of the experimental group were higher than those of the control group,the differences were statistically significant (P＜0.05).Conclusion EEG biofeedback therapy combined with rehabilitation training has a good effect on children with spastic cerebral palsy,it can significantly improve the motor function and brain function of children.It is the gospel of the family of millions of children with cerebral palsy.
2020 Vol. 27 (1): 153-156 [Abstract] ( 78 ) HTML (37 KB)  PDF  (0 KB)  ( 11 )
157 Before and after comparison of the anti-platelet aggregation effect of Clopidogrel replaced to Ticagrelor
WANG Guang-liang; WU Xue-mei
Objective To explore the comparison of anti-platelet aggregation effect of Clopidogrel replaced to Ticagrelor in patients with acute coronary syndrome.Methods Thirty-one patients with acute coronary syndrome treated in Peking University International Hospital from April to November 2018 were selected as the research objects,all patients received thromboelastomeric adenosine diphosphate (ADP) inhibition rate test (stage A data) after clopidogrel treatment,then discontinuing Clopidogrel and replaced it with Ticagrelor to test the ADP inhibition rate (stage B data)of the thromboelastometry chart again,the results of the ADP inhibition rate tests was compared.After the Clopidogrel was replaced with Ticagrelor,the ADP inhibition rate test was performed on the thromboelastometry chart,the test was divided into three groups according to the time interval between the blood collection time point and the last dose of Clopidogrel,the first group (24-＜36 h),the second group (36-＜96 h),and the third group (≥96 h).The general data of the three groups and the ADP inhibition rate of the thromboelastic diagrams at the A and B stages were compared,and CYP2C19 genotype was detected in 24 patients.Results The thromboelastomeric ADP inhibition rate of three groups in B stage was higher than that in A stage,the difference was statistically significant (P＜0.05).17 of the 24 patients with CYP2C19 genotypes (CYP2C19*1/*1) were normal,among the 17 cases,10 cases (58.8%) took clopidogrel and the inhibition rate of ADP was less than 30%,however,the inhibition rate of ADP increased to more than 50% in 9 of the 10 patients after replacement with Ticagrelor.Conclusion The replacement of Clopidogrel with Ticagrelor has better anti-platelet aggregation effect,and the treatment of Ticagrelor in patients with acute coronary syndrome has better anti-platelet aggregation effect.Even in patients with normal metabolism,there may be resistance to Clopidogrel,and the anti-platelet aggregation effect is improved after replacement with Ticagrelor.
2020 Vol. 27 (1): 157-161 [Abstract] ( 105 ) HTML (43 KB)  PDF  (0 KB)  ( 17 )
162 Clinical effect of Cefuroxime Sodium combined with San′ao Tablets in the treatment of emphysema complicated with infection
ZHANG Tong
Objective To investigate the clinical effect of Cefuroxime Sodium combined with San′ao Tablet in the treatment of emphysema complicated with infection.Methods A total of 180 patients with emphysema complicated with infection treated in our hospital from January 2015 to December 2018 were divided into control group and observation group by simple randomization method,with 90 cases in each group.The control group was treated with Cefuroxime Sodium,while the observation group was treated with Cefuroxime Sodium combined with San′ao Tablets.The total effective rate,improvement of lung function and incidence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant (P＜0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant (P＜0.05).After treatment,partial pressure of carbon dioxide (PaCO2) in the observation group was lower than that in the control group,and the levels of partial pressure of arterial oxygen (PaO2) and expiratory lolume in the first second (FEV1) in the observation group were higher than that in the control group,with statistically significant differences (P＜0.05).Conclusion The clinical effect of Cefuroxil Sodium combined with San′ao Tablets in treating patients with emphysema and infection is significant,reducing the total incidence of adverse reactions,it is worthy of cinical application.
2020 Vol. 27 (1): 162-164 [Abstract] ( 135 ) HTML (33 KB)  PDF  (0 KB)  ( 15 )
165 Clinical effect of Dydrogesterone combined with Estradiol Valerate on the treatment of dysfunctional uterine bleeding
TAN Wen-qiang; LIANG Fa-liang; ZHONG Mei-gong; WU Zhuo-jian
Objective To evaluate the clinical effect of Dydrogesterone combined with Estradiol Valerate on the treatment of dysfunctional uterine bleeding.Methods A total of 84 patients with functional uterine bleeding admitted to our hospital from January to December 2018 were selected as the study objects,they were divided into control group and experimental group according to the coin grouping method,with 42 cases in each group.The control group was treated with Dydrogesterone,while the test group was treated with Dydrogesterone Tablets combined with Estradiol Valerate Tablets.The bleeding control time,ovulation recovery after drug withdrawal and adverse reactions were compared between the two groups.Results The bleeding control and complete hemostasis time of the test group were shorter than those of the control group,and the differences were statistically significant (P＜0.05).A total of 17 cases in the control group resumed ovulation,and 28 cases in the test group resumed ovulation.The recovery rate of ovulation in the test group was higher than that in the control group,and the difference was statistically significant (χ2=5.791,P＜0.05).The incidence of adverse reactions occurred of 5 cases in the control group and 6 cases in the test group.There was no significant difference in the incidence of adverse reactions between the two groups (χ2=0.105，P=0.745).Conclusion Dydrogesterone combined with Estradiol Valerate treatment can effectively shorten the symptoms bleeding time,promote the recovery of ovulation function,and it is worth popularizing.
2020 Vol. 27 (1): 165-167 [Abstract] ( 82 ) HTML (31 KB)  PDF  (0 KB)  ( 14 )
168 Effect of acupunctural therapy combined with acupoint catgut embedding in the treatment of sciatica
LI Jin-yan； YANG Li
Objective To compare the effect of acupunctural therapy combined with acupoint catgut embedding and conventional acupunctural in the treatment of sciatica.Methods From January 2016 to September 30,2017,72 patients with sciatica from the department of acupuncture and massage in both outpatient clinic and inpatient of Traditional Chinese Medicine Hospital of Mile City were selected as the study subjects.They were divided into acupuncture group and embedding group by the random number table method,with 36 cases in each group.Patients in the acupuncture group were treated with conventional acupunctural therapy,and patients in the embedding group were treated with acupunctural therapy combined with acupoint catgut embedding.The total therapeutic efficiency of the two groups were compared.The visual analogue scale (VAS) score on pain at 5 and 10 days after treatment,the six-point behavioral rating (BRS-6) score,the modified Japanese Orthopedics Association lower back pain (JOA) score,and the follow-up JOA score at 3 months after treatment were compared between the two groups.Results After 10 days of treatment,the total effectiveness rate of the embedding group was 97.22%,which was higher than that of the acupuncture group accounting for 86.11%,with statistically significant difference (P＜0.05).After 5 and 10 days of treatment,the VAS and BRS-6 scores in the embedding group were lower than those in the acupuncture group,the differences were statistically significant (P＜0.05).The JOA score in the embedding group was higher than that in the acupuncture group,with statistically significant difference (P＜0.05).After 3 months of follow-up,the total improvement rate (100.00%) of patients in the embedding group was higher than that in the acupuncture group (94.44%),with statistically significant difference (P＜0.05).Conclusion Acupunctural therapy combined with acupoint catgut embedding in the treatment of patients with sciatica not only obtains an obvious short-term analgesic effect,but also has a long-term curative effect with a low recurrence rate.It is worthy of clinical application.
2020 Vol. 27 (1): 168-170转174 [Abstract] ( 88 ) HTML (36 KB)  PDF  (0 KB)  ( 16 )
171 Clinical effect of electroacupuncture combined with traditional Chinese medicine fumigation in the treatment of scapulohumeral periarthritis
XIONG Yun； WANG Wen-ting； PAN Hua
Objective To investigate the clinical effect of electroacupuncture combined with traditional Chinese medicine fumigation in the treatment of scapulohumeral periarthritis.Methods Sixty patients with scapulohumeral periarthritis treated in our hospital from May 2016 to May 2018 were selected as subjects.By computer numbering,they were divided into observation group (n=30) and control group (n=30) according to odd or even number.The control group was treated with electroacupuncture,and the observation group was added with traditional Chinese medicine fumigation.The total effectiveness rate,pain degree,activity of daily living and shoulder joint recovery were compared between the two groups.Results The total effectiveness rate was 100.00% in the observation group,which was higher than that in the control group accounting for 86.67%,and the difference was statistically significant (P＜0.05).The visual analogue scale (VAS) score for pain in the observation group was lower than that in the control group,the difference was statistically significant (P＜0.05).The improved Barthel index daily living ability scale (MBI) score in the observation group was higher than that in the control group,the difference was statistically significan (P＜0.05).After treatment,the anterior flexion,posterior extension,abduction,internal rotation and external rotation of the shoulder range of motion scale (ROM) scores of the observation group were higher than those of the control group,the differences were statistically significant (P＜0.05).Conclusion The use of electroacupuncture combined with traditional Chinese medicine fumigation for scapulohumeral periarthritis can remarkably improve the patients′ limb numbness and swelling,relieve pain and improve the daily activities of patients.
2020 Vol. 27 (1): 171-174 [Abstract] ( 81 ) HTML (34 KB)  PDF  (0 KB)  ( 13 )
175 Investigation and analysis of status of domestic cesarean scar diverticulum
ZHANG Hong-hui; LUO Wen-xiang; CUI Xiang-hua; LIU Qiao-ping; HE Yu-ning; SHI Li-fang; WANG Ai-li; WANG Lu
Objective To investigate the status of cesarean scar diverticulum (CSD).Methods On the homepage of Wanfang database,the key words "uterine incision diverticulum/defect/false cavity" or "uterine scar diverticulum/defect/false cavity" or "uterine scar diverticulum/defect/false cavity" or "cesarean scar diverticulum/defect/false cavity" or"cesarean scar diverticulum/defect/false cavity" or "cesarean scar diverticulum/defect/false cavity" were input.The "cross-database search" and "all journals" were selected,"limited annual range" was from 1982 to 2016,all Chinese documents on CSD were searched,and then statistical analysis was made according to time,region and hospital level.Results There were 322 articles and 12 646 cases of CSD in Wanfang database.The earliest time was in 2007.With the development of the times,the proportion of the number of documents and cases increased rapidly.By 2015,the number of documents (110 articles) was 3,1 times higher than that in the previous 5,7 years (2007-2011,2007-2013),while the number of cases(5920 cases)was 8 and 2 times of the previous 5,7 years respectively.There were 29 provinces/municipalities directly under the central government/autonomous region/special administrative region,accounting for 85.29% (29/34).Among them,the top five provinces were Guangdong,Hu′nan,He′nan,Beijing and Zhejiang,and the last five provinces were Jilin,Qinghai,Inner Mongolia Autonomous Region,Xinjiang Uygur Autonomous Region and Anhui.Documents of other medical units such as tertiary hospitals,secondary hospitals,first-class hospitals,family planning guidance service stations and those unable to check the level of hospitals accounted for 65.84% (212/322),27.33% (88/322),1.86% (6/322),2.80% (9/322) and 2.17% (7/322),respectively,and cases accounted for 65.04% (8225/12 646) and 29.73% (3760/12 646),1.32% (167/12 646),1.76% (222/12 646) and 2.15% (272/12 646).Conclusion CSD in China is increasing rapidly with the development of the times,and has certain regional and hospital level distribution trend.It deserves close attention and consideration of obstetric clinicians.Paying attention to the study of cesarean section uterine incision management mode and reducing cesarean section rate are the fundamental measures to prevent CSD.
2020 Vol. 27 (1): 175-179 [Abstract] ( 79 ) HTML (50 KB)  PDF  (0 KB)  ( 13 )
180 Analysis of blood culture contamination in the first quarter of 2019 in our hospital
YU Luo-li
Objective To analyze the blood culture contamination in the first quarter of 2019 in order to increase the qualified rate of clinical blood culture,so that the clinical diagnosis and treatment of bloodstream infection can be carried out more effectively.Methods The total number of blood culture samples (n=6459) and the total number of contaminated bottles (n=42) from January to March in 2019 were collected using the laboratory information system.The monthly contamination rate was calculated based on the data.The contamination in every department was summed up and analyzed,to find the source of highest contamination,and then put forward targeted measures to reduce the contamination rate.Results The contamination rate was 0.69% in January,0.51% in February and 0.71% in March.Coagulase negative Staphylococcus was the main contaminating bacteria,accounting for 69.05%.The highest contamination rate was in ICU,accounting for 42.86%.The total contamination rate in medical and surgical departments was 42.86%,which was similar to that in ICU.Conclusion There are many causes of contamination,and blood culture contamination cannot be ignored.Effectively preventing and reducing contamination is very beneficial to the diagnosis and treatment of clinical blood infections and the application of drugs.It is helpful to guide the clinical treatment to regularly count the contamination rate of samples sent to each department of the hospital.
2020 Vol. 27 (1): 180-182 [Abstract] ( 83 ) HTML (30 KB)  PDF  (0 KB)  ( 10 )
183 Application effect of Zhenhuang Pills combined with Teprenone aerosol inhalation in patients undergoing tonsillectomy
TANG Juan; LIN Hui; WEN Ying-hao; DAI Feng; YI Qing-ping; JIANG Li-ping
Objective To explore the effect of Zhenhuang Pills combined with Teprenone aerosol inhalation in patients undergoing tonsillectomy.Methods A total of 160 patients who underwent tonsillectomy in our hospital from January 2013 to January 2017 were selected and randomly divided into groups A,B,C and D,40 cases in each group.Group A was given Zhenhuang Pills and Teprenone aerosol inhalation,Group B was given Zhenhuang Pills aerosol inhalation,Group C was given Teprenone aerosol inhalation,Group D was given routine nursing.The pain,congestion and edema,bleeding,pharyngeal foreign body sensation,behavioral measurement,time of white membrane formation and exfoliation were compared among the four groups.Results Postoperative pain score of group A was lower than that of other groups.24 hour postoperatively,the scores of congestion,edema,bleeding,pharyngeal foreign body sensation and behavioral determination of group A were better than those of other groups.The time of white membrane formation,falling off and hospitalization of group A were shorter than those of other groups,and the hospitalization cost was lower than that of other groups,the differences were statistically significant (P＜0.05).Conclusion The application of pneumatic atomization inhalation of Zhenhuang Pills plus Teprenone after tonsillectomy can reduce pain,local hyperemia,edema and bleeding and promote wound healing,improve the quality of life of patients,is worthy of clinical application for its significant effect,few adverse reactions and simple operation.
2020 Vol. 27 (1): 183-186 [Abstract] ( 61 ) HTML (45 KB)  PDF  (0 KB)  ( 13 )
187 Application effect of comprehensive nursing in elderly patients with herpes zoster
YU Yuan; ZHANG Yan-hua
Objective To explore the effect of comprehensive nursing in elderly patients with herpes zoster.Methods A total of 60 elderly patients with herpes zoster who received treatment in our hospital from December 2016 to December 2018 were selected.They were divided into control group (n=30) and study group (n=30) according to random number table method.Patients in the control group were given routine nursing,and patients in the study group were given comprehensive nursing intervention.The pain degree before and after nursing,nursing effect and nursing total satisfaction were compared between the two groups.Results Before nursing,there was no significant difference in visual analogue scale (VAS) score between the two groups (P＞0.05).After nursing,VAS score in the study group was lower than that in the control group,the difference was statistically significant (P＜0.05).The VAS scores of the two groups after nursing were lower than those before nursing,the differences were statistically significant (P＜0.05).The duration of antiblister,scab formation,pain relief and pain disappearance were shorter in the study group than those in the control group,the differences were statistically significant (P＜0.05).The total satisfaction of the patients in the study group (96.67%) was higher than that in the control group (80.00%),the difference was statistically significant (P＜0.05).Conclusion Comprehensive nursing intervention for elderly patients with herpes zoster treatment can not only effectively alleviate the pain of patients,but also promote the recovery of patients,and it can achieve a high degree of nursing satisfaction,which is worthy of promotion in clinical practice.
2020 Vol. 27 (1): 187-189 [Abstract] ( 59 ) HTML (32 KB)  PDF  (0 KB)  ( 12 )
190 Clinical study of perioperative stepwise eating and drinking in orthopedic patients
LIU Yan; CHEN Xue-qin; ZHANG Li
Objective To investigate the clinical application value of perioperative stepwise eating and drinking in orthopedic patients.Methods A total of 200 orthopedic perioperative patients who were admitted to our hospital from January 2018 to April 2019 were enrolled in the study.They were divided into control group and experimental group according to the time of fasting and banned drinking,with 100 cases in each group.In the control group,patients were fasted 12 h before surgery,banned drinking 4 h before surgery.Six hours after surgery,patients were encouraged to drink a small amount of water.One day after surgery,they were fed fluid diet.In the experimental group,patients were fasted 6 h before surgery,and banned drinking 2 h before surgery.After anesthesia awaking,patients were provided with water in stepwise according to their needs at 10,30 min and 1,2,3,4 h,5-15 ml each time.Four hours after anesthesia awaking,they were provided with normal diet.The incidence of adverse reactions,anal exhaust time,hospital stay,comfort (evaluated with visual analogue scale [VAS]),total satisfaction and changes in laboratory indicators(hemoglobin [HGB],albumin [ALB],prealbumin [PA]and fasting blood glucose) were compared between the two groups.Results The incidence rates of hunger,thirst and throat discomfort in the experimental group (7.00%,9.00%,22.00%) were lower than those in the control group accounting for 17.00%,19.00%,and 36.00%,respectively,with statistically significant differences (P＜0.05).There were no significant differences in the incidence rates of nausea and vomiting,diarrhea,and abdominal distension between the experimental group (5.00%,0.00%,2.00%) and the control group (3.00%,1.00%,4.00%) (P＞0.05).One hour before surgery,in the experimental group,the levels of HGB,ALB,PA and fasting blood glucose were (130.54±24.28) g/L,(39.23±5.31) g/L,(319.83±31.96) mg/L,(5.93±0.97) mmol/L,and in the control group,the levels of HGB,ALB,PA and fasting blood glucose were (122.78±23.37) g/L,(35.14±5.18) g/L,(286.24±31.49) mg/L,and (5.26±0.72) mmol/L,respectively.One hour after surgery,the levels of HGB,ALB,PA and fasting blood glucose in the experimental group were (132.18±27.56) g/L,(39.46±5.28) g/L,(319.56±31.85) mg/L,(5.89±0.92) mmol/L,and in the control group,the levels of HGB,ALB,PA,fasting blood glucose were (121.46±22.59) g/L,(35.08±5.19) g/L,(285.27±31.42) mg/L,(5.24±0.69) mmol/L,respectively.The levels of HGB,ALB,PA and fasting blood glucose in the experimental group 1 h before surgery and 1 h after surgery were all higher than those in the control group,with statistically significant differences (P＜0.05).The anal exhaust time ([9.14±1.89]h) and hospital stay ([11.26±1.53]d) of the experimental group were shorter than those of the control group ([15.92±2.68]h,(14.49±1.67]d),VAS score ([2.53±0.82]points) was lower than that of the control group ([5.82±1.09]points),and the differences were statistically significant (P＜0.05).The total satisfaction of the patients in the experimental group (97.00%) was higher than that in the control group (89.00%),and the difference was statistically significant (P＜0.05).Conclusion The clinical application value of perioperative stepwise eating and drinking in orthopedic patients is high,which can effectively reduce the incidence of hunger,thirst and throat discomfort,promote the recovery of gastrointestinal function,shorten the hospital stay,and improve comfort and satisfaction of patients.
2020 Vol. 27 (1): 190-193 [Abstract] ( 77 ) HTML (38 KB)  PDF  (0 KB)  ( 8 )
194 Effect of voice training combined with psychological intervention on improving anxiety and depression in patients with voice diseases
YANG Jian-ying; ZHONG Yan-ping; LU Wan-mei
Objective To explore the effect of voice training combined with psychological intervention on improving anxiety and depression in patients with voice diseases.Methods A total of 100 patients with voice disease who were admitted to our hospital from February 2016 to November 2018 were selected as subjects,they were divided into control group and observation group according to the random number method,with 50 cases in each group.The control group received routine symptomatic nursing,and the observation group received voice training combined with psychological intervention.Nursing effect,self-rating anxiety scale (SAS) score,self-rating depression scale (SDS) score and incidence of adverse reactions were compared between the two groups.Results The total nursing effective rate of the observation group was higher than that of the control group,and the difference was statistically significant (P＜0.05).After 4 and 8 weeks of nursing,the SAS and SDS scores in the observation group were lower than those in the control group,with statistically significant differences (P＜0.05).The incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant (P＜0.05).Conclusion Voice training combined with psychological intervention has a significant role in improving anxiety and depression in patients with voice diseases,the incidence of adverse reactions is low and it is worthy of clinical use.
2020 Vol. 27 (1): 194-196 [Abstract] ( 75 ) HTML (33 KB)  PDF  (0 KB)  ( 10 )
197 Application effect of score of restlessness and sedation in ICU patients with mechanical ventilation
ZHANG Di-ying; FAN Liu; SUN Hong-guo
Objective To explore the application effect of score of agitation and sedation in patients with mechanical ventilation in ICU.Methods A total of 80 cases of mechanical ventilation patients hospitalized in ICU of our hospital from January to March 2019 were selected.According to random number table method,they were divided into control group and study group,40 cases in each group.The control group was evaluated according to nurses′ subjective experience,and the experimental group was evaluated by score of agitation and sedation.The total incidence of adverse events,duration of mechanical ventilation,duration of sedation and duration of endotracheal intubation extraction were compared between the two groups.Results The total incidence of adverse events in the study group (15.00%) was lower than that in the control group (40.00%),the difference was statistically significant (P＜0.05).The duration of mechanical ventilation,sedative drug use and endotracheal intubation extraction were shorter in the study group than those of the control group,with statistical differences (P＜0.05).Conclusion Using score of restlessness and sedation can effectively evaluate the restlessness and sedation of patients,shorten the treatment time of patients and reduce the incidence of adverse events.It is worthy of use in clinical practice.
2020 Vol. 27 (1): 197-199 [Abstract] ( 77 ) HTML (33 KB)  PDF  (0 KB)  ( 16 )
200 Effect of 360° seamless nursing on blood pressure management and pregnancy outcome in patients with pregnancy-induced hypertension
XIAO Zhi-ying ; XIE Qing-hua; LYU Mei-tao
Objective To inquire the effect of 360° seamless nursing on blood pressure management and pregnancy outcome in patients with pregnancy-induced hypertension.Methods Seventy-six patients with pregnancy-induced hypertension admitted to our hospital from July 2017 to July 2018 were enrolled in the study.They were randomly divided into the general group (37 cases) and the study group (39 cases).The general group was applied general nursing,and the study group was applied 360° seamless nursing on the basis of the general group.Blood pressure before and after nursing,labor,and delivery outcomes before and after nursing were compared between two groups.Results Before nrrsing,there was no significant difference in systolic blood pressure (SBP) and diastolic blood pressure (DBP) between the two groups (P＞0.05).After nursing,the SBP and DBP levels in the two groups were lower than those before the nursing,SBP and DBP levels of the study group were lower than those of the general group,the differences were statistically significant (P＜0.05).The first,second and total labor periods of the study group were shorter than those of the general group,the differences were statistically significant (P＜0.05).The incidence of intrauterine distress,premature delivery,cesarean section,neonatal asphyxia,macrosomia,and postpartum hemorrhage in the study group was lower than that of the general group,the differences were statistically significant (P＜0.05).Conclusion The application of 360° seamless nursing in patients with pregnancy-induced hypertension can reduce blood pressure,shorten labor and improve pregnancy outcome.
2020 Vol. 27 (1): 200-202 [Abstract] ( 80 ) HTML (31 KB)  PDF  (0 KB)  ( 12 )
203 Application of self-made foot leg fixator in patients with lower extremity dysfunction and long-term bed rest
XIAO Yue
Objective To analyze the application effect and clinical value of self-made foot leg fixator in patients with lower extremity dysfunction and long-term bed rest.Methods A total of 60 patients with lower extremity dysfunction and long-term bed rest who were treated in our hospital from November 2018 to May 2019 were selected and divided into group A and group B according to random number table method,30 cases in each group.Group A was given the traditional nail shoe and splint fixation method,while group B was given the self-made foot and leg fixation frame.The clinical effect of the two groups was compared.Results After intervention,the foot comfort score of group B was higher than that of group A,and the difference was statistically significant (P＜0.05).After intervention,the self-rating anxiety scale (SAS) and self-rating depression scale (SDS) scores in group B were lower than those in group A,with statistically differences (P＜0.05).Conclusion The application of self-made foot and leg fixator in patients with lower extremity dysfunction and long-term bed rest can improve the comfort level of patients and reduce negative emotional such as anxiety and depression,which is worthy of clinical application.
2020 Vol. 27 (1): 203-205转209 [Abstract] ( 62 ) HTML (31 KB)  PDF  (0 KB)  ( 15 )
206 Effect of recreational therapy and nursing intervention on sleep disorder and agitation behavior in patients with Alzheimer′s disease
LI Ye-hong； LI Jin-nong ； YU Xue-ying ； SHAO Li-chuan ； FENG Yin-jie； ZHU Jin-ye； RUAN Chun-rui； WANG Fei-yan
Objective To analyze the effect of occupational recreational therapy and nursing intervention on sleep disorder and agitation behavior in patients with Alzheimer′s disease.Methods From April 2018 to January 2019,69 patients with Alzheimer′s disease were selected as the research subjects,and they were randomly divided into experimental group (35 cases) and control group (34 cases).The experimental group received occupational recreational therapy plus nursing intervention,and the control group received routine nursing.The scores of the mini-mental state examination (MMSE),Co-hen-Mansfield agitation inventory (CMAI),and Pittsburgh sleep quality index (PSQI) before and after nursing intervention were analyzed in the two groups,and the incidence of safety events was compared between the two groups.Results There was no significant difference in MMSE score between the two groups before nursing intervention(P＞0.05).The MMSE scores of patients in the experimental group after 8 and 16 weeks of nursing intervention were higher than those in the control group,and the differences were statistically significant (P＜0.05).There was no significant difference in CMAI score between the two groups before nursing intervention (P＞0.05).The CMAI scores of patients in the experimental group after 8 and 16 weeks of nursing intervention were lower than those in the control group,and the differences were statistically significant (P＜0.05).There was no significant difference in PSQI score between the two groups before nursing intervention (P＞0.05).The PSQI scores of patients in the experimental group after 8 and 16 weeks of nursing intervention were lower than those in the control group,and the differences were statistically significant (P＜0.05).The total incidence rate of safety events after nursing intervention in the experimental group was 0.00%,which was lower than the 11.76% in the control group,and the difference was statistically significant (P＜0.05).Conclusion The application of occupational recreational therapy and nursing intervention in patients with Alzheimer′s disease can not only improve the quality of sleep,but also avoid the occurrence of aggressive behavior,reduce the incidence of safety events and improve the life quality of patients,which has significant clinical value.
2020 Vol. 27 (1): 206-209 [Abstract] ( 60 ) HTML (38 KB)  PDF  (0 KB)  ( 12 )
210 Application effect of peripheral venous indwelling needle combined with predictive nursing in neurological intravenous infusion
LUO Dan-dan
Objective To explore the application effect of peripheral venous indwelling needle combined with predictive nursing in neurological intravenous infusion,and to provide guidance for the diagnosis and treatment of patients.Methods The clinical data of 500 patients with intravenous infusion in neurology department of our hospital from July 2017 to July 2018 were retrospectively analyzed,and they were divided into control group (250 cases) and observation group (250 cases) according to different nursing methods.The patients in the control group were given peripheral venous indwelling needle,and the patients in the observation group were given peripheral venous indwelling needle combined with predictive nursing.The indwelling time of intravenous indwelling needle,the total incidence rate of adverse reactions and total satisfaction were compared between the two groups.Results The indwelling time of patients in the observation group was longer than that in the control group,and the difference was statistically significant (P＜0.05).The total incidence rate of complications in the observation group (13.20%) was significantly lower than that in the control group (34.80%),and the difference was statistically significant (χ2=31.9737,P=0.0000).The total satisfaction of patients in the observation group (92.00%) was significantly higher than that in the control group (76.80%),and the difference was statistically significant (χ2=21.9346,P=0.0000).Conclusion Peripheral venous indwelling needle combined with predictive nursing has a good effect in the application of neurological infusion.It can significantly prolong the indwelling time,reduce the incidence rate of adverse reactions,significantly improve satisfaction of patients,and is worthy of wide application.
2020 Vol. 27 (1): 210-212 [Abstract] ( 69 ) HTML (34 KB)  PDF  (0 KB)  ( 11 )
213 Influence of early rehabilitation nursing on rehabilitation effect of patients with cerebral infarction hemiplegia aphasia
HUANG Chun-mei
Objective To analyze the influence of early rehabilitation nursing on rehabilitation effect of patients with cerebral infarction hemiplegia aphasia.Methods Sixty patients with cerebral infarction hemiplegia aphasia who were admitted to our hospital from April 2015 to July 2018 were enrolled in the study.They were divided into control group and observation group according to the random number table method,30 cases in each group.The control group used basic nursing,and the observation group adopted early rehabilitation nursing.The scores of language recovery,daily living ability and cerebral infarction recovery were compared between the two groups before and after nursing.Results The scores of language recovery in the observation group were significantly higher than those in the control group at 1,3,and 6 weeks after nursing,and the differences were statistically significant (P＜0.05).There was no significant difference in the score of daily living ability before nursing between the two groups (P＞0.05).After nursing,the daily living ability score of the observation group was significantly higher than that of the control group,and the difference was statistically significant (P＜0.05).The score of daily living ability in the observation group after nursing was significantly higher than that before nursing,and the difference was statistically significant (P＜0.05).The score of daily living ability in the control group after nursing was significantly higher than that before nursing,and the difference was statistically significant (P＜0.05).There was no significant difference in the score of cerebral infarction recovery before nursing between the two groups (P＞0.05).The score of cerebral infarction recovery after nursing in the observation group was significantly lower than that before nursing,and the difference was statistically significant (P＜0.05).The score of cerebral infarction recovery after nursing in the control group was significantly lower than that before nursing,and the difference was statistically significant (P＜0.05).The score of cerebral infarction recovery after nursing in the observation group was significantly lower than that in the control group,and the difference was statistically significant (P＜0.05).Conclusion Early rehabilitation nursing for patients with cerebral infarction and hemiplegia aphasia can improve aphasia and has clinical application value.
2020 Vol. 27 (1): 213-216 [Abstract] ( 76 ) HTML (36 KB)  PDF  (0 KB)  ( 13 )
217 Application effect of intensive intervention on lifestyle in the nursing for type 2 diabetes mellitus
LYU Chun-lan
Objective To explore the application effect of intensive intervention on lifestyle in the nursing for type 2 diabetes mellitus (T2DM).Methods A total of 106 patients with T2DM admitted to our hospital from June 2017 to May 2018 were enrolled as subjects,they were divide into the control group and observation group by a random number table method,with 53 cases in each group.The control group carried out routine nursing intervention,and the observation group gave intensive lifestyle intervention on the basis of the control group.The two groups were compared before and 6 months after the intervention in glucose metabolism related indicators (fasting blood glucose,2 h postprandial blood glucose,glycosylated hemoglobin [HbA1c]) and self-management ability.Results Before the intervention,there were no significant differences in fasting blood glucose,2 h postprandial blood glucose and HbA1c levels between the two groups (P＞0.05).After 6 months of intervention,the fasting blood glucose,2 h postprandial blood glucose and HbA1c levels of the two groups were lower than those before intervention,and the fasting blood glucose,2 h postprandial blood glucose and HbA1c levels of the observation group were lower than those of the control group,with statistically significant differences (P＜0.05).Before intervention,there were no significant differences in blood glucose monitoring,foot care,diet,exercise and compliance between the two groups (P＞0.05).After 6 months of intervention,the blood glucose monitoring,foot care,diet,exercise and compliance scores of the observation group were higher than those before intervention,and the blood glucose monitoring,foot care,diet,exercise and compliance scores of the observation group were higher than those of the control group,with statistically significant differences (P＜0.05).Conclusion Intensive intervention on lifestyle for patients with T2DM can improve their self-management ability and benefit for their glycemic control.
2020 Vol. 27 (1): 217-219 [Abstract] ( 61 ) HTML (31 KB)  PDF  (0 KB)  ( 17 )
220 Application effect of acupuncture combined with rehabilitation treatment on stroke patients
LI Su-dan
Objective To study the effect of acupuncture combined with rehabilitation treating stroke (CAV) and its effect on national institutes of health stroke scale (NIHSS) score.Methods A total of 98 patients with CAV from March 2016 to April 2018 were selected and randomly divided into control group and study group,49 cases in each group.The control group was treated with routine rehabilitation,and the study group was treated with routine rehabilitation combined with acupuncture.The total incidence of complications,NIHSS score and quality of life (QOL) score were compared between the two groups.Results The total incidence of complications in the study group was lower than that in the control group (P＜0.05); the NIHSS score of the study group was lower than that of the control group (P＜0.05); the QOL score of the study group was higher than that of the control group,the difference was statistically significant (P＜0.05).Conclusion Acupuncture combined with rehabilitation can significantly improve the muscle tension of CAV patients,improve the limb ability of patients through rehabilitation,and reduce the risk of complications.It is beneficial to ensure the quality of life of patients and their families,and it is worthy of clinical promotion.
2020 Vol. 27 (1): 220-222 [Abstract] ( 80 ) HTML (32 KB)  PDF  (0 KB)  ( 11 )
223 Application effect of quality control circle in postoperative nursing of minimally invasive percutaneous nephrolithotomy and holmium laser lithotripsy
LIN Yu-zhi; PU Yong-jie
Objective To investigate the nursing value of quality control of patients with minimally invasive percutaneous nephrolithotomy and holmium laser lithotripsy (MPCNL).Methods One hundred patients with kidney stones who underwent MPCNL admitted to our hospital from November 2017 to November 2018 were enrolled in the study.The patients were divided into observation group and control group according to random number table method,50 cases in each group.The control group was given routine nursing,the observation group adopted quality control circle nursing.The quality of the operation and nursing,degree of the pain and the total complication rate were compared between two groups.Results The amount of bleeding in the observation group was less than that in the control group,the operation time and hospitalization time were shorter than those of the control group,the quality of nursing score was higher than that of the control group,visual analogue scale (VAS) score was lower than that of the control group,and the total complication rate was lower than that of the control group,the differences were statistically significant (P＜0.05).Conclusion Patients with kidney stones treated with MPCNL actively carry out quality control circle activities in postoperative care,which can improve the quality of surgery and care,reduce pain and ensure clinical safety.
2020 Vol. 27 (1): 223-225 [Abstract] ( 64 ) HTML (31 KB)  PDF  (0 KB)  ( 11 )
226 Application effect of perioperative nursing intervention in patients with pregnancy-induced hypertension
ZHAO Qian-hong
Objective To study the application effect of perioperative nursing intervention in patients with pregnancyinduced hypertension (PIH).Methods A total of 120 patients with PIH received in our hospital from May 2016 to June 2018 were selected and divided into study group and control group according to random number table method,60 cases in each group.The control group received routine nursing,while the study group received perioperative nursing intervention.Negative emotions,pregnancy outcomes and blood pressure were compared between the two groups.Results Self-rating depression scale (SDS) and self-rating anxiety scale (SAS) scores,and the total incidence of adverse preqncmay outcomes in the study group were lower than those in the control group,and the systolic and diastolic blood pressure were lower than those in the control group,with statistical differences (P＜0.05).Conclusion Perioperative nursing intervention can relief the negative emotions of patients with PIH,improve pregnancy outcomes,make blood pressure return to normal,and promote the recovery of patients.
2020 Vol. 27 (1): 226-228 [Abstract] ( 78 ) HTML (31 KB)  PDF  (0 KB)  ( 10 )
229 Application effect of comfortable nursing in perioperative period of cesarean section
LI Li
Objective To explore the effect of comfort nursing in the perioperative period of cesarean section.Methods A total of 60 parturients with cesarean section from January to December 2018 were enrolled in this study.They were divided into control group and observation group according to the principle of randomized control,30 cases in each group.The control group received routine perinatal nursing,while the observation group carried out perioperative comfort nursing on this basis.The changes of mental state before and after intervention,recovery after operation and nursing satisfaction were compared between the two groups.Results The self-rating anxiety scale (SAS) and self-rating depression scale (SDS) scores of the observation group after intervention were lower than those of the control group,with significant differences (P＜0.05).The anal exhaust time,lactation time and the first time out of bed activity time of the observation group were earlier than those of the control group,the pain score and comfort score after operation were lower than those of the control group,and the hospitalization time after operation was shorter than that of the control group,with significant differences (P＜0.05).The total satisfaction of maternal nursing in the observation group was higher than that in the control group,the difference was statistically significant (P＜0.05).Conclusion Comfortable nursing can improve the psychological state of cesarean section women,promote the recovery after operation,and improve the quality of nursing service,which is worthy of clinical promotion.
2020 Vol. 27 (1): 229-231 [Abstract] ( 73 ) HTML (31 KB)  PDF  (0 KB)  ( 12 )
232 Application effect of modified early warning score in the nursing of children with bronchiolitis
XIA Cui-cui; LOU Chun-yan; ZHOU Ming-ying
Objective To explore the application effect of modified early warning score (MEWS) in the nursing of children with bronchiolitis.Methods Eighty-eight children with bronchiolitis in children admitted to the First Affiliated Hospital of Nanchang University,from January 2017 to December 2018 were selected.The patients were divided into the control group and the observation group according to random number table method,44 cases in each group.The routine nursing intervention was performed on both groups.The observation group was given MEWS mechanism and early warning nursing measures.The time of symptom resolution,time of hospitalization,total incidence of complications and total family satisfaction were compared between the two groups.Results The duration of symptom resolution and hospital stay in the observation group were shorter than those in the control group,with statistical differences (P＜0.05).The total incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant (P＜0.05).The total family satisfaction of children in the observation group was higher than that of the control group,and the difference was statistically significant (P＜0.05).Conclusion The application of MEWS mechanism in the care of children with bronchiolitis and the early warning nursing measures can shorten the time of symptom resolution and hospitalization,reduce the occurrence of complications,and improve the satisfaction of children′s families,which is worthy of clinical application.
2020 Vol. 27 (1): 232-234 [Abstract] ( 73 ) HTML (31 KB)  PDF  (0 KB)  ( 10 )
235 Application of multi -dimensional extended nursing in PICC catheter management of breast cancer patients
SHI Dai-hong; JIANG Ren-lian; HE Min
Objective To explore the application effect of multi-dimensional extended nursing in PICC catheter management of breast cancer patients.Methods A total of 44 breast cancer patients with PICC catheterization in our hospital from January to June 2018 were selected as control group,while another 44 breast cancer patients with PICC catheterization in our hospital from July to December 2018 were selected as experimental group.The control group was given routine nursing,and the experimental group was given multi-dimensional extended nursing.The total incidence of catheter-related complications and compliance of catheter maintenance were compared between the two groups.Results The total incidence of complications in the experimental group was lower than that in the control group,the difference was statistically significant (P＜0.05),and the compliance of catheter maintenance in the experimental group was higher than that in the control group,the difference was statistically significant (P＜0.05).Conclusion The application of multi-dimensional extended nursing in the management of PICC catheter in breast cancer patients reduces the incidence of PICC-related complications,and improves the compliance of patients with PICC catheter maintenance.
2020 Vol. 27 (1): 235-237 [Abstract] ( 69 ) HTML (32 KB)  PDF  (0 KB)  ( 13 )
238 Application effect of family members participating in rehabilitation nursing in patients with dysphagia after stroke
ZHANG Tao; OU Mei-qiong
Objective To explore the clinical value of family members participating in rehabilitation nursing for patients with dysphagia (DAS) after stroke (CAV).Methods A total of 120 patients with DAS after CAV in our hospital from January 2017 to January 2018 were selected as the study subjects.They were divided into control group (n=60)and observation group (n=60) according to random number table method.The control group received routine rehabilitation nursing,the observation group used family members to participate in rehabilitation nursing.The swallowing function score,watian drinking water test classification,hospitalization time,hospitalization expenses and incidence of complications were compared between the two groups.Results The swallowing function score of the observation group was higher than that of the control group,with statistical difference (P＜0.05).The grading of watian drinking water test in observation group after nursing was better than that in the control group,and the difference was statistically significant(P＜0.05).The hospitalization time of the observation group was shorter than that of the control group,and the hospitalization cost was lower than that of the control group,the differences were statistically significant (P＜0.05).The incidence of complications in the observation group was lower than that in the control group,the difference was statistically significant (P＜0.05).Conclusion Family involvement in rehabilitation nursing can improve swallowing function,shorten hospitalization time,reduce hospitalization costs and the incidence of complications in patients with DAS after CAV.
2020 Vol. 27 (1): 238-240 [Abstract] ( 86 ) HTML (33 KB)  PDF  (0 KB)  ( 12 )
241 Effect of seamless nursing intervention on neurobehavior of premature infants
ZHENG Xiao-xian; HUANG Hong-shuang
Objective To investigate the effect of seamless nursing intervention on neurobehavior of premature infants.Methods One hundred premature infants admitted to our hospital from May 2017 to December 2018 were selected.They were divided into control group (n=50) and observation group (n=50) according to random number table method.The control group received routine nursing intervention,the observation group received seamless nursing intervention on the basis of routine nursing intervention.The neurobehavioral behavior of premature infants was evaluated by 20 behavioral neurometry (NBNA) score and compared.Results The NBNA scores of preterm infants in the two groups at 1 and 7 days after operation were not significantly different (P＞0.05).The NBNA score of the preterm infants in the observation group at 28 days after surgery was higher than that of the control group and 1 day after operation with statistical difference (P＜0.05).The total scores of NBNA and NBNA extra scores of the preterm infants in the observation group were higher than those in the control group with statistical differences (P＜0.05).Conclusion The intervention of seamless care is beneficial for the improvement of the neurobehavior of premature infants and is worthy of clinical promotion.
2020 Vol. 27 (1): 241-243 [Abstract] ( 76 ) HTML (32 KB)  PDF  (0 KB)  ( 14 )
244 Application effect of clinical nursing intervention in patients with pregnancy-induced hypertension treated with Magnesium Sulfate
WANG Min; LIU Chun-mei; HUANG Ye
Objective To investigate the application effect of clinical nursing intervention in patients with pregnancyinduced hypertension treated with Magnesium Sulfate.Methods A total of 54 patients with pregnancy-induced hypertension who were admitted to our hospital from February 2018 to February 2019 were selected.They were randomly divided into reference group and observation group,27 cases in each group.All patients were treated with Magnesium Sulfate.In the observation group,clinical nursing intervention was adopted,while in the reference group,routine nursing was used.The occurrence of adverse reactions,the quality of life score before and after the nursing intervention,and the natural labor rate were observed and compared in the two groups.Results The total incidence of adverse reactions in the observation group was lower than that in the reference group,and the difference was statistically significant(P＜0.05).The natural labor rate of the observation group was higher than that of the reference group,and the difference was statistically significant (P＜0.05).There was no significant difference in quality of life score before nursing intervention two groups (P＞0.05).The scores of quality of life indicators after nursing intervention in the observation group and the reference group were higher than those before the intervention,and the scores of the quality of life indicators in the observation group were higher than those in the reference group with statistical differences (P＜0.05).Conclusion Clinical nursing intervention for the nursing of patients with pregnancy-induced hypertension has a good effect,it can increase the natural labor rate and reduce the incidence of adverse reactions,it can effectively improve the quality of life of patients,which is worthy of clinical application.
2020 Vol. 27 (1): 244-246 [Abstract] ( 83 ) HTML (29 KB)  PDF  (0 KB)  ( 13 )
247 Application effect of quality control circle in the process of increasing functional exercise implementation rate of patients after sports joint operation
WU Yun; XIA Bing▲
Objective To explore the application effect of quality control circle (QCC) approach in improving the functional exercise execution rate of patients undergoing motor joint surgery,further effectively increasing functional exercise implementation rate of patients after sports joint operation.Methods A total of 111 patients admitted to our hospital from March to July 2018 were selected as the research objects,and the implementation of QCC management was conducted to compare the promotion effect of functional exercise execution rate of patients in sports joint department before and after QCC activities.Results According to the examination table,the functional exercise of patients was investigated in 6 important factors in the department of sports and joints.There were significant changes in functional exercise execution rate.The incidence of inadequate education,incorrect exercise,patients′ non-cooperation,uncooperative family members and different views from doctors and nurses after improvement was lower than that before improvement,the differences were statistically significant (P＜0.05).The improvement rate was 58.10%.The activity of QCC not only improved the practical problems existing in the nursing work of our sports joint department,but also further cultivates the sense of responsibility and problem-solving ability of circle members,improved their working happiness,and increased team cohesion.Conclusion With the application of QCC tools,establishment of functional exercise paths and corresponding standards for various sports joint diseases,and it is an effective management method.
2020 Vol. 27 (1): 247-250 [Abstract] ( 66 ) HTML (36 KB)  PDF  (0 KB)  ( 10 )
251 Application effect of kangaroo nursing in neonates with hypoxic ischemic encephalopathy
XIE Guan-wen
Objective To explore the application effect of kangaroo nursing in neonates with hypoxic ischemic encephalopathy (HIE).Methods From January 2017 to January 2019,76 cases of neonatal with HIE were selected as the research objects,according to random number table method,they were divided into experimental group and control group,38 cases in each group.The control group was given conventional nursing,the experimental group on the basis of the control group was given kangaroo care,born at the time of 2 weeks and 1 month neural development situation,the physical development of 40 d of birth and malnutrition between two groups were compared.Results The behavioral ability,passive muscle tone,active muscle tone,original reflex and general reflex of the two groups were higher at 1 month after birth than those at 2 weeks after birth,and at the same time,behavioral ability,passive muscle tone,active muscle tone,original reflex and general reflex of the children in the experimental group were higher than those in the control group,the differences were statistically significant (P ＜0.05).The weight growth,height growth and head circumference growth of the experimental group were higher than those of the control group,the differences were statistically significant (P＜0.05).The total incidence of malnutrition in the experimental group was lower than that in the control group,the difference was statistically significant (P＜0.05).Conclusion Kangaroo nursing for neonates with HIE has better clinical effect,can significantly promote the neurological development of patients,improve the physique,reduce the incidence of malnutrition in neonates,worthy of clinical promotion.
2020 Vol. 27 (1): 251-253 [Abstract] ( 57 ) HTML (31 KB)  PDF  (0 KB)  ( 10 )
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