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2018 Vol. 25, No. 7
Published: 2018-03-08
 
 
4 Clinical effect of Quanzhenyiqi Decoction in treating chronic heart failure and influence on serum humoral factors
WANG Xian；LI Hong-wei；SHI Zhen-dong；CAO Lei
ObjectiveTo expore the clinical effect of Quanzhenyiqi Decoction in the treatment of chronic heart failure(CHF)and influence on serum humoral factors.Methods126 cases of CHF patients treated in our hospital from December 2014 to December 2016 were selected as the research subjects.According to the random number table method,all patients were divided into the conventional western medicine group (the control group)and the combination of traditional Chinese and western medicine group(the observation group),with 63 cases in each group.The control group was treated with conventional western medicine.The observation group was treated with conventional western medicine and Quanzhenyiqi Decoction.Two groups were both treated for 4 weeks.Color Doppler echocardiography was performed before and 8 weeks after treatment in the two groups,left ventricular ejection fraction (LVEF),left ventricular end systolic volume (LVESV),left ventricular end systolic diameter(LVESD),left ventricular end diastolic diameter(LVEDD),left ventricular end diastolic volume (LVEDV)and stroke volum (SV)were detected.Meanwhile,serum N-terminal pro-B-type natriuretic peptide(N-proBNP),high sensitivity C reactive protein(hs-CRP),tumor necrosis factor alpha(TNF-alpha),blood and urine routine,serum electrolytes,liver and kidney function were detected.The clinical efficacy of the two groups,the curative effect of traditional Chinese medicine syndrome,the index of cardiac function and the adverse reaction were compared.Results The total clinical effective rate of the observation group was 95.2%,which was significantly higher than that of the control group(71.4%)(P＜0.05)).The total effective rate of traditional Chinese medicine syndrome in the observation group was 96.8%,which was significantly higher than that of the control group(74.6%)(P＜0.05).8 weeks after treatment,the levels of LVEF,LVEDV,LVESD,LVESV,SV,N-proBNP,hs-CRP and TNF-alpha were improved in the two groups compared with those before the treatment(P＜0.05),and those in the observation group were significantly better than those in the control group (P＜0.05).There was no adverse reaction found in the two groups.Conclusion Quanzhenyiqi Decoction in the treatment of CHF is safe and effective,which can improve the heart function index and serum level of humoral factors,and no obvious adverse reaction.
2018 Vol. 25 (7): 4-7 [Abstract] ( 168 ) HTML (34 KB)  PDF  (0 KB)  ( 33 )
8 Meta analysis of Rotigotine Transdermal Patches in the treatment of neuropsychiatric symptoms in the patients with Parkinson′s disease
WANG Hao-tian ；HE Yi；YU Gang
ObjectiveTo systematically evaluate the therapeutic effect of rotigotine transdermal patch in the treatment of neuropsychiatric symptoms of Parkinson′s disease(PD).Methods PubMed,Clinic trails,Cochrane Library,Embase database were searched.The search time was from database building to September 1,2017.RCT literature of rotigotine transdermal patch in the treatment of PD neuropsychiatric symptoms was collected.The inclusion and exclusion criteria were strictly followed by two investigators for independent screening of documents,extracting information and evaluating the quality,and the literature was reviewed by the third investigator.Meta-analysis was performed using RevMan 5.3 software.Results Finally,8 randomized controlled trials were included,with a total of 1675 PD patients.Meta analysis showed that,in the aspects of mood/indifference of NMSS,sleep/fatigue of BDI-Ⅱ,AS and NMSS,the scores of PDQ-8 and PDQ-39,rotigotine transdermal patch was superior to the control group,and the difference was statistically significant[emotional/indifferenceofNMSS：MD=-2.5,95%CI（-4.11,-0.89）,P=0.002;BDI-Ⅱ：MD=-1.19,95%CI（-2.30,-0.08）,P=0.04;AS：MD=-1.56,95%CI （-2.67,-0.45）,P=0.006;sleep/fatigue of NMSS：MD=-2.03,95%CI （-3.08,-0.98）,P=0.001;PDQ-8：MD=-4.93,95%CI（-6.79,-3.07）,P＜0.00001;PDQ-39：MD=-3.52,95%CI （-5.25,-1.79）,P＜0.0001].The study bias of PDSS-2 was too large.The results of SHAPS were not statistically significant[MD=-0.12,95%CI （-0.58,0.34）,P=0.61].ConclusionRotigotine Transdermal Patch can effectively improve PD neuropsychiatric symptoms and improve the quality of life of patients compared with the control group.The conclusion needs to be further studied.
2018 Vol. 25 (7): 8-12 [Abstract] ( 189 ) HTML (37 KB)  PDF  (0 KB)  ( 34 )
13 Meta analysis of the effect of different anesthetic methods on vertebral percutaneous kyphoplasty in osteoporotic vertebral compression fractures
CHENG Kang-yao；MO Wen；LIU Dong-mei；LYU Wei-bo
ObjectiveTo evaluate the clinical effects of general anesthesia and local anesthesia to patients undergoing percutaneous kyphoplasty for osteoporotic vertebral compression fractures.Methods Papers involving the effect of general anesthesia and local anesthesia to patients undergoing percutaneous kyphoplasty for osteoporotic vertebral compression fractures were searched in Cochrane Library,JBI Library,Pubmed,Medline,EMbase,OVID,CNKI,CBM,VIP and Wanfang Data to collect the randomized controlled trials (RCTs)by computer retrieval.A quality assessment scale was developed to identify each potentially qualified document,moderate and high quality documents were selected for data extraction.RevMan 5.3 software was used for Meta-analysis.Results indexes included intraoperative blood loss,operation time,bone cement leakage rate,nerve injury rate,VAS scores,hospital stays,postoperative kyphosis angle after 1 day.Results 6 eligible documents were identified for pooled analysis.The results of Meta-analyses showed that the nerve injury rate of the local anesthesia group was lower than that of the general anesthesia group[OR=0.16,95%CI(0.04,0.73),P=0.02＜0.05],the hospital stays was shorter than that in the general anesthesia group[WMD=-2.80,95%CI(-3.82,-1.78),P＜0.05],but the postoperative kyphosis angle after 1 day of the general anesthesia group was smaller than that of the local anesthesia[SMD=0.39,95%CI(0.04,0.74),P=0.03＜0.05].There was no difference between general anesthesia and local anesthesia group in other indexes.Conclusion The data indicates that local anesthesia can reduce the incidence of nerve injury,shorten the hospitalization time,but kyphosis angle recovery of general anesthesia group is better than local anesthesia.Choosing anesthesia way is depending on the actual situation of patients and doctors.
2018 Vol. 25 (7): 13-16 [Abstract] ( 182 ) HTML (34 KB)  PDF  (0 KB)  ( 29 )
17 Clinical analysis of the risk factors and short-term prognosis of thrombocytopenia among patients undergoing intra-aortic balloon pump counterpulsation
LUO Jie-hong； LIU Jin-guang ；SHEN Yuan-sheng
ObjectiveTo analyze and explore the risk factors of thrombocytopenia and its influence on the short-term prognosis in patients undergoing intra-aortic balloon pump(IABP)counterpulsation.Methods 108 patients who received IABP in our hospital from March 2014 to March 2016 were selected and divided into the thrombocytopenia group(74 cases)and the non thrombocytopenia group(34 cases)according to whether thrombocytopenia occurred.The platelet and clinical features of the selected patients were analyzed retrospectively.Results Thrombocytopenia occurred in 74 patients(68.5%,74/108),and the degree of thrombocytopenia increased with the duration of IABP support.Multi factor Logistic regression analysis showed that baseline platelet count was the only influential factor in this study(P＜0.01),and there was no significant difference between the two groups in mortality and 30 days re-admission rate(P＞0.05).Conclusion The degree of thrombocytopenia is related to the duration of IABP support.Lower baseline platelet count is independent risk factor for thrombocytopenia,which is not affect the short-term prognosis.
2018 Vol. 25 (7): 17-20 [Abstract] ( 180 ) HTML (32 KB)  PDF  (0 KB)  ( 36 )
21 The research progress of chemokine receptor 6 in liver metastasis of colorectal cancer
LI Juan-fang； LI Yuan-fei
Colorectal cancer is a worldwide malignant tumor whose main cause of death is liver metastasis.The liver is the most important target organ for the metastasis of colorectal cancer.Chemokine receptor 6(CCR6)is a G protein-coupled receptor that mediates cellular biological effects and exerts chemotaxis by binding to the chemokine CCL20.In recent years,it has been found that CCR6 plays an important role in the metastasis of many kinds of tumors,especially in the metastasis of colorectal cancer.The progress of CCR6 in the metastasis of colorectal cancer is reviewed.
2018 Vol. 25 (7): 21-24 [Abstract] ( 182 ) HTML (34 KB)  PDF  (0 KB)  ( 42 )
25 Research progress on pathogenesis and drug treatment of ulcerative colitis
HE Xiao-rui
Ulcerative colitis(UC)is a chronic and recurrent colitis disease.Its etiology and pathogenesis is not entirely clear yet.At present,UC is considered to be related to multiple factors and multiple links.Aminosalicylates and glucocorticoids were the first choice to treat UC.Immunosuppressants is mostly used in severe refractory UC,and the effect is accurate,but the adverse reaction is obvious.Antibiotics,microecologics,biologics and traditional Chinese medicine can also play a role in the treatment of UC.This review will summarize the pathogenesis and drug treatment of UC.
2018 Vol. 25 (7): 25-27 [Abstract] ( 164 ) HTML (31 KB)  PDF  (0 KB)  ( 32 )
28 Influence of oral administration of 1200 IU Vitamin D3 on serum vitamin D,bone mineral density and lower extremity function in elderly patients with vitamin D-deficient
CHEN Ping-jun；HUANG Xiao-hong；WANG Xia；XIAO Ting；LIU Qi-sheng
ObjectiveTo investigate the influence of oral administration of 1200 IU Vitamin D3on serum 25-hydroxyvitamin D[25(OH)D],bone mineral density(BMD)and lower extremity function in elderly patients with vitamin D-deficient.Methods From October 2015 to December 2016,56 elderly patients with vitamin D-deficient treated in our hospital were selected as research subjects.According to vitamin D3took or not,they were divided into the control group(n=29)and observation group(n=27).In the control group,30 min sun bathe daily and proper exercise were necessary.In the observation group,on the basis of the control group,oral administration of Vitamin D3and Caltrate D was added.25(OH)D,osteocalcin,parathyroid hormone,BMD,and walking time of lower extremities were compared between the two groups before intervention,and after 6 and 12 months intervention.Results The serum calcium,serum 25(OH)D,osteocalcin and BMD of the two groups were higher than those before intervention,and after 6 and 12 months intervention,and the above-mentioned indexes in the observation group were all higher than those in the control group (P＜0.05).PTH level after 6 and 12 months intervention in the two groups was lower than that before intervention,and PTH level of in the observation group after 6 and 12 months intervention was lower than in the control group (P＜0.05).The muscle strength of the two groups after intervention was better than that before intervention (P＜0.05).The 8 step walking time after 6 and 12 months intervention in the observation group was longer than that in the control group (P＜0.05).Conclusion O-ral administration of 1200 IU vitamin D3 is beneficial to bone health,and improve BMD as well as the lower limbs function,which has a certain clinical application value and is worthy of promotion and application.
2018 Vol. 25 (7): 28-30 [Abstract] ( 210 ) HTML (26 KB)  PDF  (0 KB)  ( 32 )
31 Application and value of Anding Injection in cardiac color doppler examination for patients with anxiety disorder
LI Jiang-ping；YOU Hai；LI Jiang-hong
ObjectiveTo evaluate the clinical application value of Anding Injection in cardiac color doppler examination for patients with anxiety disorder.Methods 80 patients needing with cardiac color Doppler ultrasonography and treated in our hospital from March 2016 to February 2017 were selected and they were grouped according to the random number method,and each group had 40 cases.The observation group was given Anding to conduct sedation in cardiac color doppler examination in the observation group,while the control group was given conventional treatment,then mainly psychological nursing intervention,appropriate constraint was given.The change of heart rate,oxygen saturation in the inspection process,and the proportion of facial color,pupil and skin color and luster change in the two groups were observed,and The change of respiratory rhythm and frequency of two groups were compared,and time-consuming of examination and the change of anxiety and depression score after intervention and the quiet state of the patient during the examination were counted in the two groups.Results The heart rate and respiratory of the observation group was slower than those of the control group,the oxygen saturation was higher than that of the control group (P＜0.05).The total proportion of facial color,pupil and skin color and luster change in the observation group were significantly lower than those of the control group (P＜0.05).The proportion of quiet and sleep in the observation group was significantly higher than that in the control group,and the proportion of restlessness was significantly lower than that of the control group(P＜0.05).The anxiety and depression score in the observation group after intervention were significantly lower than those of the control group (P＜0.05).Time-consuming of examination in the observation group was significantly shorter than that of the control group(P＜0.05).Conclusion Anding Injection used in cardiac color doppler examination for patients with anxiety disorder can better maintain vital signs of patients,avoid the occurrence of complications in the inspection process,improve the psychological state of patients,and let the patients examine quietly,shorten the inspection time,avoid interference,and and obtain more accurate results.
2018 Vol. 25 (7): 31-33转37 [Abstract] ( 226 ) HTML (32 KB)  PDF  (0 KB)  ( 40 )
34 Efficacy of Tiotropium Bromide combined with noninvasive ventilator treating COPD complicated with typeⅡrespiratory failure and its influence on serum TNF-α,IL-27,CRP and oxygenation function of patients
LYU Jun；LIU Xu；ZHANG Ji-xian
ObjectiveTo explore the efficacy of Tiotropium Bromide combined with non-invasive ventilation treating COPD complicated with typeⅡrespiratory failure and its influence on the inflammatory marker and oxygenation function of patients.Methods Ninety patients admitted into our hospital due to COPD from June 2014 to February 2016 were included in the study,and they were grouped using the random number table method.Forty-five patients in the control group were given Tiotropium Bromide,while 45 patients in the obeservation group were combined with noninvasive ventilator,and 7 days were a course of treatment.The improvement of blood gas index and inflammatory factors before and after treatment in patients between the two groups was compared,and the clinical efficacy between the two groups was compared.Results Before treatment,there were no statistically significant differences between the two groups in any indicators(P＞0.05).After treatment,PaO2and PaO2/FiO2were higher,and PaCO2was lower in the observation group than that in the control group (P＜0.05).TNF-α,IL-27 and CRP level were lower in the observation group than that in the control group (P＜0.05).The total effective rate of the observation group was 91.11%,which was higher than that of the control group 73.33% (P＜0.05).Conclusion The effect of Tiotropium Bromide combined with noninvasive ventilator treating COPD complicated with typeⅡrespiratory failure is obvious and can better improve oxygenation function and inflammation reaction.It is worth popularizing.
2018 Vol. 25 (7): 34-37 [Abstract] ( 155 ) HTML (32 KB)  PDF  (0 KB)  ( 37 )
38 Effect analysis of emergency integrated green channel curing acute upper gastrointestinal hemorrhage
ZHAO Xian-wu
ObjectiveTo explore the clinical effect of emergency integrated green channel curing acute upper gastrointestinal hemorrhage.Methods One hundred patients with acute upper gastrointestinal hemorrhage treated in our hospital from June 2013 to August 2017 were selected as research objects.The patients were divided into the two groups according to before and after the establishment of emergency integrated green channel.Forty-six patients before the establishment of emergency integrated green channel were taken as the control group,while 54 patients after the establishment of emergency integrated green channel were taken as the research group.Patients in the control group were given the routine emergency curing method,while patients in the research group were given emergency integrated green channel model.Average hemostasis time,mean volume of blood transfusion,average hospitalization period and average hospital cost,and operation rate,recurrent bleeding rate and mortality in patients between the two groups were compared.Results The average hemostasis time and the average hospitalization time in the study group were shorter than those in the control group,the average blood transfusion volume and the average hospitalization cost were less than those in the control group,and the operative rate,recurrent bleeding rate and mortality rate were all lower than those in the control group(P＜0.05).Conclusion Emergency integrated green channel curing acute upper gastrointestinal hemorrhage not only can control the amount of bleeding effectively,shorten the hospitalization time,reduce the hospital cost,but also can reduce operation rate,recurrent bleeding rate and mortality,which can ensure the health and safety of life of patients,and can be used as an emergency treatment scheme applied in clinic.
2018 Vol. 25 (7): 38-40 [Abstract] ( 183 ) HTML (27 KB)  PDF  (0 KB)  ( 35 )
41 Clinical application value of Botulinum Toxin Type A after repair operation of facial scar
LIU Yang
ObjectiveTo explore the application values of Botulinum Toxin Type A after repair operation of facial scar.Methods Ninety patients received the repair operation of facial scar from March 2015 to March 2017 were selected as the research objects,and they were divided into the control group of 45 cases and the observation group of 45 cases according to the random number table method.The control group of incision were painted the Beifuxin Gel then given dressing,while the observation group were injected the Botulinum Toxin Type A after operation.The scar repair,satisfaction degree of patients and incidence of adverse reactions of two groups were observed.Results There was no significant difference in VSS and SBSES score between the two groups before treatment(P＞0.05).After the treatment,the abovementioned score in the observation group was significantly lower than that of the control group,and the difference was statistically significant(P＜0.05).The total satisfaction rate of repair in the observation group was 97.78%,which was significantly higher than that in the control group of 86.67%,and the difference was statistically significant(P＜0.05).The total incidence of adverse reactions in the observation group was 8.89%,compared with the control group of 2.22%,the difference was not statistically significant(P＞0.05).Conclusion The injection of Botulinum Toxin Type A for repair of facial scar can effectively enhance the repair effect,improve the satisfaction degree of patients,and the safety is high,thus it is worth promoting.
2018 Vol. 25 (7): 41-43 [Abstract] ( 184 ) HTML (26 KB)  PDF  (0 KB)  ( 35 )
44 Application effect of selective cholangiography in emergency laparoscopic cholecystectomy
YIN Zhao-cheng； YIN Yao-hua； PENG Yan； LIU Guo-sheng
ObjectiveTo investigate the clinical effect and safety of selective cholangiography (LOC)in emergency laparoscopic cholecystectomy.Methods Ninety-two patients with acute cholecystitis admitted into our emergency department of our hospital from April 2013 to April 2017 were selected as the study subjects,and they were divided into the observation group and control group according to the different surgical methods.Each group had 46 patients.Patients in the two groups were given laparoscopic cholecystectomy,in the observation group,LOC was given in laparoscopic cholecystectomy.Perioperative related indicators(operation time,the rate of transferring to laparotomy,intraoperative blood loss and hospital stay),postoperative complications(biliary tract injury,incision infection,residual stones in common bile duct,biliary tract infections,abdominal infection and postoperative syndrome)were compared in patients between the two groups.Results There was no significant difference in operative time,hospital stay,and the incidence of incision infection,biliary tract infection and abdominal infection between the two groups(P＞0.05).In the observation group,the rate of transferring to laparotomy,the rate of biliary tract injury,residual stones in common bile duct and the incidence of postoperative syndrome were significantly lower than those of the control group,and intraoperative blood loss in the observation group was significantly fewer than that of the control group (P＜0.05).Conclusion LOC in emergency laparoscopic cholecystectomy can effectively find triangular gallbladder trigonometry variation,such as the deputy right hepatic duct,variation of cystic duct inflow and so on,and it can effectively avoid the occurrence of iatrogenic biliary tract injury,reduce the rate of transferring to laparotomy and postoperative complications,reduce the incidence of residual stones to improve the quality of surgery to promote the rehabilitation of patients,clinical curative efficacy is good and the safety is high.It is worth promoting and applying in emergency laparoscopic cholecystectomy,especially in primary hospitals in clinic.
2018 Vol. 25 (7): 44-46转50 [Abstract] ( 188 ) HTML (29 KB)  PDF  (0 KB)  ( 34 )
47 Clinical efficacy study of Amiodarone in urgent application for patients with coronary heart disease tachyarrhythmia
HE Lin-heng
ObjectiveTo study the clinical effect of Amiodarone in emergency patients with coronary heart disease(CHD)tachyarrhythmia.Methods From February 2015 to May 2017,50 patients with CHD tachyarrhythmia treated in our hospital were selected as subjects.By computer distribution method,they were evenly divided into observation group and control group,25 cases in each group.In the control group,routine drug for treatment was applied,while in the observation group,Amiodarone was adopted.The total effectiveness rate,time of symptoms disappearing,recovery time of normal electrocardiography (ECG),therapeutic time,incidence of adverse reactions and improvement of clinical indicators were compared between the two groups.Results The total effectiveness rate of the patients in the observation group(92.00%)was higher than that of the control group(60.00%),and the difference was statistically significant(P＜0.05).The time of symptoms disappearing,recovery time of normal ECG and therapeutic time in the observation group were(5.21±1.12)d,(8.21±1.67)d and (11.45±2.01)d respectively,which were all shorter than those in the control group ([6.47±2.11],[11.26±2.36]and[15.24±2.15]d),and the differences were statistically significant(P＜0.05).In the observation group,the incidence of adverse reactions was 12.00%,which was lower than that of the control group (40.00%),and the difference was statistically significant(P＜0.05).In the observation group,the heart rate was(76.32±1.02)times/min,which was lower than that in the control group([137.54±1.68]times/min),and the difference was statistically significant(P＜0.05).The PR interval and Q-T interval were (152.23±1.36)ms and (38.56±1.02)ms in the observation group respectively,which were longer than those in the control group([145.65±1.85],[36.54±1.12]ms),and the differences were statistically significant(P＜0.05).Conclusion Implementation of Amiodarone in the treatment of CHD patients with tachyarrhythmia obtain a remarkable effect by improving the effectiveness rate,and shortening the time of symptoms disappearance,ECG recovery time and treatment time,which is worthy of further promotion and application.
2018 Vol. 25 (7): 47-50 [Abstract] ( 198 ) HTML (30 KB)  PDF  (0 KB)  ( 33 )
51 Clinical analysis of a new oral anticoagulant drug combined with Aspirin in the treatment of nonvalvular atrial fibrillation
HUANG Han-hui；HUANG Kai
ObjectiveTo investigate the clinical effect of new oral anticoagulant(Dabigatran)combined with Aspirin in the treatment of nonvalvular atrial fibrillation.Methods One hundred and fifty cases of nonvalvular atrial fibrillation treated in our hospital from February 2014 to August 2016 were selected as the subjects.According to the random number table method,they were divided into control group,research group 1 and research group 2,50 cases in each group.The controlgroupwastreated with Warfarin,and the research group 1 was treated with Dabigatran,and the research group 2 was treated with Aspirin Tablets combined with Dabigatran.The changes of coagulation index and cerebral hemorrhage,upper gastrointestinal bleeding,transient ischemic attack,pulmonary embolism,cerebral embolism and death were compared in the three groups before and after treatment.Results Before treatment,there was no significant difference in coagulation index between the three groups(P＞0.05).After treatment,the coagulation indexes in the three groups were significantly higher than those before treatment,and the differences were statistically significant(P＜0.05),while there was no significant difference in coagulation index in the three groups after treament(P＞0.05).No pulmonary embolism and death were found in all three groups.The incidence of transient ischemic attack,cerebral embolism,cerebral hemorrhage and upper gastrointestinal bleeding of research group 1 and research group 2 were both lower than those in the control group,and the differences were statistically significant(P＜0.05).The incidence of hemorrhage and upper gastrointestinal bleeding of research group 1 were lower than those in the research group 2,and the differences were statistically significant(P＜0.05).Conclusion In the treatment of nonvalvular atrial fibrillation,Dabigatran combined with Aspirin Tablets has no significant improvement in efficacy compared with Dabigatran alone,but increases the risk of bleeding.Compared with warfarin alone,combination therapy can reduce the incidence of transient ischemic attack,cerebral embolism and other events.
2018 Vol. 25 (7): 51-53 [Abstract] ( 177 ) HTML (28 KB)  PDF  (0 KB)  ( 28 )
54 Effect comparison of anticoagulation and double antithrombotic therapy in the analysis of coronary heart disease with atrial fibrillation
CUI Yue
ObjectiveTo analyze and compare the therapeutic effect of anticoagulant and double antithrombotic therapy in patients with coronary heart disease (CHD)and atrial fibrillation (AF).Methods A total of 100 patients with CHD and AF treated in our hospital from January 2015 to August 2016 were selected as subjects.The patients were divided into research group(n=50)and control group(n=50)according to the double-blind method.In the control group,double antithrombotic therapy was used,while in the research group,anticoagulation was adopted.The situation of follow-up visits,utilization rate of proton pump inhibitor(PPI)and scores of HAS-BLED and CHADS2 were comparatively analyzed.Results There was no significant difference between the two groups in secondary end point events and bleeding events(P＞0.05).The main end point event in the research group was significantly lower than that in the control group,and the difference was statistically significant(P＜0.05).The PPI utilization rate in the study group (14.00%)was significantly lower than that in the control group (42.00%),and the difference was statistically significant(χ2=9.722,P=0.001).The CHADS2 score of the two groups was not statistically significant(P＞0.05),and the patients in the research group had a statistically significant difference compared with the control group(P＜0.05).Conclusion For patients with CHD and AF,the anticoagulant effect is better than that of double antithrombotic therapy.The former improves therapeutic effect and reduces the risk of hemorrhage simultaneously,and has a high application value in clinical practice.
2018 Vol. 25 (7): 54-56 [Abstract] ( 161 ) HTML (29 KB)  PDF  (0 KB)  ( 38 )
57 Effect of percutaneous coronary intervention with transcatheter Tirofiban in the treatment of acute myocardial infarction
LIN Yu-peng； WU Qiang；WANG Chu-lin； SHEN Ning；XU Ming-wei
ObjectiveTo observe the effect of percutaneous coronary intervention combined with transcatheter Tirofiban in the treatment of acute myocardial infarction.Methods A total of 120 acute myocardial infarction patients treated in our hospital from October 2014 to May 2017 were selected as subjects,and were divided into control group and treatment group according to random number table method,60 patients in each group.The control group was treated with percutaneous coronary intervention,the treatment group was treated with transcatheter Tirofiban on the basis of the control group.The postoperative TIMI blood classification,LVEF level,the incidence of cardiovascular events and bleeding were compared between the two groups.Results After the operation,the TIMI blood classification of patients in the treatment group was better than that in the control group,and LVEF was higher than that in the control group,the differences were statistically significant(P＜0.05).The incidence of cardiovascular events in the treatment group(5.0%)was lower than that in the control group(16.7%),and the difference was statistically significant(P＜0.05).There was no statistically significant difference in the incidence of bleeding between the two groups (P＞0.05).Conclusion The effect of percutaneous coronary intervention combined with Tirofiban in the treatment of acute myocardial infarction is remarkable,safe and reliable.It is worth spreading and applying.
2018 Vol. 25 (7): 57-59 [Abstract] ( 163 ) HTML (28 KB)  PDF  (0 KB)  ( 34 )
60 Clinical curative effect observation of sublingual administration of Captopril curing emergency of hypertension
LIANG Hong-guang
ObjectiveTo observe the clinical curative effect of observation of sublingual administration of Captopril curing emergency of hypertension.Methods Seventy-five patients with emergency of hypertension treated in emergency department of our hospital from July 2015 to December 2016 were selected.The subjects were divided into the control group(35 cases,Nitroglycerin Injection was used)and observation group(40 cases,sublingual administration of Captopril was added)according to the different wards for attending doctor.The antihypertensive effect of after 10,30,60 min treatment was evaluated,and the change of blood pressure index before treatment and after 10,30,60 min treatment were compared between the two groups.Results The clinical treatment rate of observation group after 10,30,60 min treatment was 32.5%,72.5%and 90.0%respectively while the control group was 20.6%,58.8%and 79.4%,and the treatment effect in the observation group was better than that in the control group(P＜0.05).There was no significant difference in blood pressure between the two groups before medication(P＞0.05).After 10,30,60 min treatment,SBP and DBP value in the observation group were lower than those in the control group(P＜0.05).Conclusion Clinical effect observation of sublingual administration of Captopril curing emergency of hypertension is ideal,the improvement of blood pressure is good.
2018 Vol. 25 (7): 60-62 [Abstract] ( 165 ) HTML (27 KB)  PDF  (0 KB)  ( 26 )
63 Feasibility analysis of Salvia Miltiorrhiza Polyphenols combined with routine therapy in the treatment of acute cerebral infarction
HE Guo-rui
ObjectiveTo analyze the feasibility of Salvia Miltiorrhiza Polyphenols combined with routine therapy in the treatment of acute cerebral infarction.MethodsSeventy-eight patients with acute cerebral infarction who were admitted to our hospital from June 2015 to June 2017 were selected as observation objects and divided into control group(n=39,conventional therapy)and treatment group (n=39,given Salvia Polyphenols with conventional therapy),according to the random number table method.The treatment effect,NIHSS score before and after treatment changes,adverse reactions of two groups were observed and compared.Results The total effective rate of the control group was lower than that of the treatment group,the difference was statistically significant(P＜0.05).After treatment for 1 and 2 weeks,the NIHSS scores of two groups were lower than that before treatment,the NIHSS score of the treatment group was lower than that in the controi group(P＜0.05).There was no adverse reaction in the control group,there was no significant difference between the two groups(P＞0.05).Conclusion Salviae Miltiorrhizae Polyphenols combined with routine therapy in the treatment of acute cerebral infarction with exact effect,can effectively improve the neurological deficit,safe and feasible,and can be used as an ideal treatment in clinical active promotion.
2018 Vol. 25 (7): 63-65 [Abstract] ( 187 ) HTML (25 KB)  PDF  (0 KB)  ( 32 )
66 Analysis on the therapeutic effect of family intervention on community schizophrenia
YU Wei； LI Hai-yun； LI Qun
ObjectiveTo investigate the curative effect of family intervention on community schizophrenia.Methods A total of 132 patients with schizophrenia who were “cured”and discharged in our hospital from September 2015 to September 2016 were numbered.Afterwards,according to completely random principle,the patients were divided into research group and control group,66 cases in each group.The control group was given antipsychotics only.The study group was received one year of family intervention on the basis of the control group.BPRS and SCL-90 questionnaire were used to evaluate and compare upon enrollment and after family intervention.Results One year after the intervention,the BPRS score in the study group was(31.69±7.51)points,which was significantly lower than that of(42.15±6.94)points in the control group.The overall score of SCL-90 in the study group was (152.29±29.76)points,which was significantly lower than that in the control group(183.67±2.59)points.The medication compliance in the study group was significantly higher than that of the control group(P＜0.01).Conclusion Family intervention is significant for alleviating mental symptoms,improving mental health of family caregivers and improving medication compliance.
2018 Vol. 25 (7): 66-68转71 [Abstract] ( 197 ) HTML (29 KB)  PDF  (0 KB)  ( 32 )
69 Clinical effect of Yindan Xinnaotong Soft Capsules in the treatment of lacunar infarction
YAN Xue；DING Xiao-lan ；HAO Bo
ObjectiveTo investigate the clinical effect of Yindan Xinnaotong Soft Capsules in the treatment of lacunar infarction.Methods From March 3,2016 to March 4,2017,94 patients with lacunar infarction admitted into our hospital were selected as research objects and evenly divided into two groups,47cases in each group.In control group,routine therapy was used,while in observation group,on the basis of the control group,Yindan Xinnaotong Soft Capsules was added.The score of neurologic impairment,fibrinogen level,hemorheological index,and clinical effect in the two groups were compared.Results In the observation group,the score of neurological impairment and fibrinogen level were both lower compared with those in the control group after therapy(P＜0.05).The hemorheological indexes including high shear viscosity,low shear viscosity,plasma viscosity,and hematocrit after treatment in the observation group were all superior to those in the control group(P＜0.05).The total clinical effectiveness rate was 93.62%,much higher than that in the control group,the differences were statistically significant(P＜0.05).Conclusion Yindan Xinnaotong Soft Capsules can obtain a definite effect on treating patients with lacunar infarction,which is beneficial to the recovery of neurological function,and improvement of fibrinogen level and hemorheological indexes.
2018 Vol. 25 (7): 69-71 [Abstract] ( 231 ) HTML (25 KB)  PDF  (0 KB)  ( 28 )
72 The effect of percutaneous nephrolithotomy without real time imaging and percutaneous nephrolithotomy for the treatment of upper urinary calculi
WU Jun-yong ；SHI Ming ；PENG Ping ；LUO Yan-ping； ZHONG Shuang-hui；LIU Fu-kang； YANG Jie-lin
ObjectiveTo explore the clinical effect of minimally invasive percutaneous nephrolithotomy(MPCNL)in the treatment of upper urinary calculi without real-time imaging.Methods The clinical data of 247 cases of upper urinary calculi in our hospital were analyzed retrospectively and divided into the observation group and the control group according to the different surgical methods.110 cases of the control group were treated with clinical standard percutaneous nephrolithotomy(PCNL),and 137 patients in the observation group were treated with MPCNL,the surgical indicators and postoperative related indicators of two groups were analyzed.Results Compared with the control group,the observation group had shorter operative time,lower transfusion ratio and lower analgesic dosage.There were a significant differences in operative index between the two groups(P＜0.05）.Compared with the control group,the VAS score of the observation group was low,and the length of hospital stay was short.The differences between the two groups of patients VAS score and length of stay were statistically significant(P＜0.05）.The incidence of severe complications in the control group(3.63%)was higher than that in the observation group(0.73%),but there was no significant difference in the incidence of severe complications between the two groups(P＞0.05).Conclusion MPCNL can significantly improve operative indicators of upper urinary calculi,shorten hospitalization time,reduce operative pain and reduce postoperative complication rate,which is conducive to postoperative rehabilitation,and is worthy of clinical reference and promotion.
2018 Vol. 25 (7): 72-74 [Abstract] ( 184 ) HTML (27 KB)  PDF  (0 KB)  ( 32 )
75 Effect of minimally invasive percutaneous nephrolithotomy combined with flexible ureteroscope in the treatment of complex renal calculi and its influence on urokinase and renal function in patients
HU Xiao-bao； ZHOU Dong-ping； HUANG Hai-peng ；YANG Xiao-ping； LUO Hui-lin； LIU Xiao

ObjectiveTo investigate the effect of minimally invasive percutaneous nephrolithotomy combined with flexible ureteroscope in the treatment of complex renal calculi and its influence on urokinase and renal function in patients.Methods From March 2014 to March 2017,82 patients with complex renal calculi treated in our hospital were enrolled in the study and grouped according to a random number table.In the control group (n=41),only minimally invasive percutaneous nephrolithotomy was used,while in the observation group(n=41),flexible ureteroscope was combined.The general conditions,serum creatinine,urokinase,and complications of the two groups were compared.ResultsThe hospital stay and operation time in the observation group were shorter,and the amount of bleeding was less compared with those in the control group,with statistical differences(P＜0.05).At the 7 day after treatment,the creatinine level was lower,while the urokinase was higher in the observation group than that in the control group,which were displayed statistical differences(P＜0.05).In the observation group,the removal rate of stone in one time was 92.68%,higher than that in the control group accounting for 73.17%,and the incidence of renal function injury was lower in the observation group (P＜0.05).Conclusion Combination of minimally invasive percutaneous nephrolithotomy and flexible ureteroscope obtains a significant effect on treating complex renal calculi,with a high removal rate,small trauma,and mild damage to renal function,which is worthy of promotion.
2018 Vol. 25 (7): 75-77 [Abstract] ( 177 ) HTML (27 KB)  PDF  (0 KB)  ( 35 )
78 Clinical analysis of ultrasound-guided transretal prostatic biopsy with 10-12 cores in diagnosis of prostate cancer
ZHOU Li；ZHANG Kai-zhong；YE Guang-meng

ObjectiveTo investigate the clinical effects of ultrasound-guided transretal prostatic biopsy(TPB)with 10-12 cores in diagnosis of prostate cancer.Methods One hundred and twenty cases of highly-suspected prostate cancer from October 2015 to October 2017 were selected,and they were divided into two groups by random number table,60 cases in each group.The control group was given ultrasound-guided TPB with 6-cores,while the experimental group was given ultrasound-guided TPB with 10-12 cores.The positive detection rate of prostate cancer by two detection methods were compared between the two groups.The postoperative complications of two groups were recorded.Results The success rate of biopsy in two groups were 100.00%,the positive detection rate of prostate cancer in experimental group was 45.00%(27/60),which was higher than 20.00%(12/60)of control group(P＜0.05).The incidence of complications after biopsy in experimental group and control group were 61.67%(37/60)and 60.00%(36/60),there was no statistical difference(P＞0.05).Conclusion Ultrasound-guided TPB with 10-12 cores in detection of prostate cancer can increase clinical diagnosis rate and not add the incidence of complications after biopsy,and it is safe and reliable,which can be applied in screening of prostate cancer.
2018 Vol. 25 (7): 78-80 [Abstract] ( 181 ) HTML (26 KB)  PDF  (0 KB)  ( 32 )
81 Clinical effect analysis of retroperitoneoscope combined with lower abdominal incision in the treatment of renal pelvic cancer
SUN Ai-jun
ObjectiveTo study the clinical effect of retroperitoneoscope combined with lower abdominal incision in the treatment of patients with renal pelvic cancer.Methods From January 2013 to January 2016,42 patients with renal pelvic cancer in our department were randomly divided into group A and group B,21 cases in each group.In group A,retroperitoneoscope combined with lower abdominal incision was used,while in group B,open radical resection for the renal pelvic carcinoma was performed.The surgical results and complications were compared between the two groups.After 1 year follow up visits,the recurrence and metastasis of tumors were observed in the two groups.Results The operations of the two groups were all successful.However,the intraoperative amount of bleeding,time of gastrointestinal recovery,and hospital stay were lower/shorter in group A compared with group B,with statistical differences(P＜0.01).There were no significant differences in the incidence of postoperative complications or tumor recurrence and metastasis rate between the two groups(P＞0.05).Conclusion Combination of retroperitoneoscope combined with lower abdominal incision has the advantages of small trauma,few complications,and little amount of bleeding.
2018 Vol. 25 (7): 81-83转86 [Abstract] ( 175 ) HTML (29 KB)  PDF  (0 KB)  ( 31 )
84 Clinical effect observation of endoscopic ureteral double J tube implantation combined with Paishi Granule in the treatment of urinary calculi
YU Tao ；SUN Chang-hai；XING Shao-qiang； DONG Li-ming
ObjectiveTo observe the effect of endoscopic ureteral double J tube implantation combined with Paishi Granule in the treatment of urinary calculi.Methods From April 2016 to March 2017,79 patients with upper urinary calculi treated in our outpatient clinic were selected as research objects.According to different clinical therapeutic methods,they were divided into control group (n=37,extracorporeal lithotripsy plus Paishi Granule)and research group(n=42,endoscopic ureteral double J tube implantation plus Paishi Granule).The therapeutic effect by the two methods was evaluated,the postoperative complications were recorded,and the stone clearance rate and a second operation were compared in both groups.Results The therapeutic rate in the research group was 95.2%,higher than that in the control group accounting for 86.5%after comparison(χ2=4.553,P＜0.05).Compared with the control group,a second operation rate was lower(χ2=10.867,P＜0.05)and the stone clearance rate was higher(χ2=11.176,P＜0.05).The incidence of postoperative complications in the research group was 7.1%,and 18.9%in the control group,with fewer complications after surgery in the research group after comparison(χ2=6.156,P＜0.05).Conclusion For patients with urinary calculi,application of double J tube implantation combined with Paishi Granule can obtain an ideal effect by high stone clearance rate and few complications.
2018 Vol. 25 (7): 84-86 [Abstract] ( 185 ) HTML (25 KB)  PDF  (0 KB)  ( 27 )
87 Clinical effect comparison of low-approach microscopic varicocelectomy and open laparoscopic varicocelectomy in the treatment of varicocele
HONG Zhao-zhan
ObjectiveTo compare and analyze the clinical effect of low-approach microscopic varicocelectomy(L-MV)and open laparoscopic varicocelectomy(LV)in the treatment of varicocele.Methods From February 2014 to January 2016,60 patients with varicocele admitted to our hospital were enrolled in this study.According to different therapeutic methods,they were divided into research group(n=30)and control group(n=30).In the control group,LV was used,while in the research group,L-MV was adopted.The sperm quality improvement,average hospital stay,recurrence rate,and incidence of complications were compared in the two groups.Results In the research group,the sperm count,sperm concentration,sperm survival rate were(42.85±3.58)×106,(25.01±3.15)×106/ml and(65.02±4.57)%,which were superior to those in the control group[(36.22±4.17)×106,(21.54±3.54)×106/ml and(56.04±4.25)%](all P＜0.05).The average hospital stay was(2.52±0.47)d in the research group,was lesser than that of the control group[(4.58±1.01)d](P＜0.05).The recurrence rate and incidence of complications in the research group were 3.33%and 3.33%respectively,both lower compared with those in the control group(20.00%,23.33%)，the differences were statistically significant(P＜0.05).Conclusion After comparison，the effect of L-MV is better for patients with varicocele,which can improve the quality of sperm,shorten hospital stay,and reduce the recurrence rate as well as the incidence of complications in high safety and good prognosis.It is worthy of application and promotion in clinical practice.
2018 Vol. 25 (7): 87-89 [Abstract] ( 191 ) HTML (25 KB)  PDF  (0 KB)  ( 30 )
90 Effect observation of 3D printing assisted small incision of tarsal sinus in the treatment of calcaneal fractures
LU Zhi-wen；YE Qing-lin；WU Bai-chu；LUO Ji-wei
ObjectiveTo observe the clinical efficacy of 3D printing assisted reduction and internal fixation with tarsal sinus small incision in treatment of calcaneal fractures.Methods 42 patients with intra-articular calcaneal fractures treated in Xintang Hospital from January to December 2016 were selected as the subjects,and divided into experimental group and control group,21 cases in each group.The control group were given conventional calcaneal lateral"L"type extended incision reduction plate internal fixation,the patients in the experimental group were treated with 3D printing assisted minimally invasive reduction and internal fixation of the tarsal sinus.The postoperative fracture healing and clinical recovery effect were observed and compared between the two groups.Results The Bohler angle and Gissane angle in the experimental group were better than those in the control group after the treatment.The excellent and good rate of calcaneal treatment in the experimental group was significantly better than that in the control group 9 months after operation.The incidence of adverse reactions in the experimental group (9.5%)was significantly lower than that in the control group(19.0%),the differences were statistically significant(P＜0.05).Conclusion The treatment of intra-articular calcaneal fractures with 3D printing assisted reduction and internal fixation with small incision of the tarsal sinus is beneficial to the reduction of calcaneal fractures,shortening the healing time of calcaneal fractures and reducing the incidence of adverse reactions.
2018 Vol. 25 (7): 90-92转99 [Abstract] ( 167 ) HTML (29 KB)  PDF  (0 KB)  ( 29 )
93 Influence of pain sensitivity on postoperative efficacy in patients undergoing lumbar spondylolisthesis
HE Bin；WANG Yong-mei；ZHANG Shao-wei
ObjectiveTo investigate the influence of pain sensitivity on postoperative efficacy in patients undergoing lumbar spondylolisthesis.Methods From July 2014 to December 2015,68 patients with lumbar spondylolisthesis treated in our hospital were retrospectively analyzed.They were provided with posterior lumbar interbody fusion(PLIF).According to the preoperative personal strain questionnaire(PSQ)score,they were divided into low PSQ(PSQ＜6.5)and high PSQ group (PSQ≥6.5),34 cases in each group.The surgical effects were followed up.Results The scores of visual analogue scale (VAS)and ODI before surgery and last follow-up visit after surgery in the high PSQ group were all higher than those in the low PSQ group,the differences were statistically significant(P＜0.05).The improvement scores of postoperative VAS and ODI at the last follow-up visit after surgery in the high PSQ group were lower than those in the low PSQ group,the differences were statistically significant(P＜0.05).Conclusion Compared with patients with low pain sensitivity,improvement of pain and disability in high pain sensitivity patients after lumbar spondylolisthesis is not remarkable.PSQ can be used to evaluate the efficacy of lumbar spondylolisthesis surgery.
2018 Vol. 25 (7): 93-95 [Abstract] ( 182 ) HTML (29 KB)  PDF  (0 KB)  ( 29 )
96 Effectiveness of Application of Calcitonin in the elderly patients with femoral neck fracture after bipolar femoral head replacement
ZHU Guang-ming；YAN Bin
ObjectiveTo investigate the effect of calcitonin in the elderly patients with femoral neck fracture after bipolar femoral head replacement.Methods A total of 59 elderly patients with femoral neck fracture who were treated with bipolar femoral head replacement in our hospital from January 2013 to June 2015 were selected as the subjects,and randomly divided into calcitonin group and control group,with 29 cases in calcitonin group and 30 cases in control group.Calcitonin was used for more than one year after the operation,and the control group was not treated with calcitonin after the replacement of the femoral head.The Harris hip scores,the hip bone density of the healthy side,the risk of re-fracture and the postoperative complications between the two groups were observed.Results All 59 patients were followed up for at least 2 years.There were no complications such as surgical incision infection,pulmonary embolism,joint dislocation and pulmonary infection in the two groups.1 case of deep vein thrombosis occurred in the control group after operation.There was no re-fracture in the calcitonin group,and 1 case in the control group were complicated with distal radius fractures at 11 months after operation.The T value of the hip bone density in the calcitonin group at 6 months,1 year and 2 years after the operation was statistically significant compared with the control group (P＜0.05).The Harris hip scores in the calcitonin group were better than those in the control group at 6 months,1 year and 2 years after operation,the differences were statistically significant(P＜0.05).Conclusion The combined use of calcitonin in elderly patients with femoral neck fracture after bipolar femoral head replacement is beneficial to improve bone mineral density and early recovery of hip joint function.
2018 Vol. 25 (7): 96-99 [Abstract] ( 157 ) HTML (29 KB)  PDF  (0 KB)  ( 30 )
100 Effect of open reduction and internal fixation in the treatment of tibial plateau fractures
SUN Zhao-jun
ObjectiveTo analyze the effect of open reduction and internal fixation in the treatment of tibial plateau fractures.Methods 32 patients with tibial plateau fractures treated in our hospital from January 20,2015 to March 12,2017 were selected as the subjects,and randomly divided into the observation group and the control group,16 cases in each group.The patients in control group were treated with routine surgery,and the patients in the observation group were treated with open reduction and internal fixation.Results The mean operation time([60.01±1.20]min),total length of stay([10.24±2.01]d)and fracture healing time([3.45±1.02]months)of patients in the observation group were superior to the mean operation time([71.45±1.07]min),total length of stay([15.45±2.17]d),and fracture healing time([5.11±1.17]months)in the control group,the differences were statistically significant(P＜0.05).The excellent and good rate of patients in the observation group was 87.50%,which was significantly different from that of 56.25%in the control group(P＜0.05).Conclusion Open reduction and internal fixation in the treatment of the patients with tibial plateau fractures can not only improve the patients′excellent and good rates,but also shorten the mean operation time,total length of stay and fracture healing time.
2018 Vol. 25 (7): 100-102 [Abstract] ( 157 ) HTML (25 KB)  PDF  (0 KB)  ( 30 )
103 Effect analysis of arthroscopicdebridementcombined with Sodium Hyaluronate Injection in the treatment of knee osteoarthritis
ZHANG Ze ；JIN Yun-long
ObjectiveTo investigate the clinical effect of arthroscopic debridement combined with Sodium Hyaluronate Injection in the treatment of knee osteoarthritis.Methods From October 2014 to October 2016,98 patients with osteoarthritis of knee joint treated in our hospital were selected as the research objects.They were divided into test group and reference group by random number table method,with 49 cases in each group.The patients in the reference group were treated with arthroscopic debridement,and the patients in the experimental group were treated with arthroscopic debridement combined with sodium hyaluronate injection for treatment.The clinical efficacy and the improvement of knee OA index between the two groups were observed and compared.Results The effective rate of the treatment group(91.83%)was significantly higher than that in the reference group(81.63%),the difference was statistically significant(P＜0.05).There were no significant differences in ISOA scores between the two groups before treatment and after one week treatment(P＞0.05),the ISOA scores at 2 months,6 months and 12 months after treatment in the experimental group were significantly lower than those in the reference group,the differences were statistically significant(P＜0.05).Conclusion The application of arthroscopic debridement combined with Sodium Hyaluronate Injection in the treatment of knee osteoarthritis can effectively improve the clinical symptoms of osteoarthritis,improve the therapeutic effect,which is worthy of further promotion.
2018 Vol. 25 (7): 103-105 [Abstract] ( 146 ) HTML (26 KB)  PDF  (0 KB)  ( 33 )
106 Observation of efficacy of hysteroscopic electrotomy plus natural progesterone and hysteroscopy plus Ethinylestradiol and Cyproterone Acetate Tablets in the treatment of endometrial polyps
YANG Cai-hong ；LI Yong-kui； LI Cui-ping ；LIN Fang
ObjectiveTo investigate the effect of hysteroscopic electrotomy plus natural progesterone and hysteroscopic electrotomy plus Ethinylestradiol and Cyproterone Acetate Tablets in the treatment of endometrial polyps.Methods Altogether 105 patients with endometrial polyps who were treated in our hospital from June 2015 to June 2016 were selected and randomly divided into group A,group B and group C according to the different treatment methods.All the patients were treated with hysteroscopic electrotomy,among which group A(35 cases)were given Ethinylestradiol and Cyproterone Acetate Tablets post-operatively;group B (35 cases)were given natural progesterone capsules post-operatively;group C (35 cases)received no medication treatment post-operatively.The clinical effective rate,recurrence rate,preoperative and post-operative endometrial thickness and hemoglobin level were compared among three groups.Results The total effective rate of group A and group B was significantly higher than that of group C,with statistically significant difference(P＜0.05);no statistically significant difference was seen between group A and group B(P＞0.05);in contrast with post-operative 6-month results,the endometrial thickness and recurrence rate of group A and group B at post-operative 1 year were significantly lower than those of group C,but the hemoglobin level was significantly higher than that of group C,with statistically significant difference(P＜0.05).Conclusion Hysteroscopic electrotomy combined with natural progestin or Ethinylestradiol and Cyproterone Acetate Tablets is effective and safe in the treatment of endometrial polyps,with high safety and low recurrence rate.
2018 Vol. 25 (7): 106-108 [Abstract] ( 139 ) HTML (27 KB)  PDF  (0 KB)  ( 36 )
109 Multiple factors analysis of recurrent respiratory tract infection in children with recurrent respiratory infection
XU Jin
ObjectiveTo explore the factors of recurrent respiratory tract infection in children.Methods From January 2015 to June 2016 in our hospital for treatment of the complete data of 152 cases of Mycoplasma pneumoniae infection in children were selected as the research object,including 52 cases of children with recurrent respiratory tract infection.Patients were followed for 1 years,the general information and clinical data were collected,many factors of the disease was determined.Results After analysis,univariate and multivariate Logistic found that age,CD4/CD8,IgA and Hp antibodies,blood zinc value was caused by multiple factors.At the same time,the incidence of children with the use of immunostimulants could reduce repeated the incidence of respiratory tract infection.Conclusion There are many factors of recurrent respiratory tract infection in children,and immune enhancer can be used to reduce the incidence of the disease.
2018 Vol. 25 (7): 109-111 [Abstract] ( 151 ) HTML (25 KB)  PDF  (0 KB)  ( 39 )
112 Clinical effect of pulmonary surfactant combined with high-frequency oscillatory ventilation and Milrinone in the treatment of persistent pulmonary hypertension of newborn
WEI Cheng-sheng； LIAO Qiu-xian
ObjectiveTo observe the clinical effect of pulmonary surfactant combined with high-frequency oscillatory ventilationandMilrinoneinthetreatmentofpersistentpulmonaryhypertensionofnewborn(PPHN).MethodsFromMarch2015 to August 2016,114 PPHN cases treated in our hospital were enrolled as research objects and evenly divided into control group 1,control group 2,and observation group in random,38 cases in each group.Only high frequency oscillatory ventilation was used in the control group 1,and combination of high frequency oscillatory ventilation and Milrinone was applied in the control group 2,while in the observation group,high frequency oscillatory ventilation combined with pulmonary surfactant and Milrinone was adopted.The therapeutic effect，pulmonary artery systolic pressure(PASP)and mechanical ventilation time among three groups were comparatively analyzed.Results The total therapeutic effectiveness rate was 26.31%(10/38)in the control group 1,47.37%(18/38)in the control group 2,and 92.11%(35/38)in the observation group.Obviously,the total therapeutic effectiveness rate in the observation group was higher than that in the other two groups.The indexes of PASP,oxygen-intake concentration,and arterial partial pressure of carbon dioxide(PaCO2)in the observation group were much lower than those in the control groups 1 and 2 (P＜0.05).Meanwhile,compared with the control groups 1 and 2,arterial oxygen pressure (PaO2)was higher,with statistical significance (P＜0.05).The total mechanical ventilation time was(83.46±9.91)h in the observation group,much shorter compared with the control groups 1 and 2,[(136.35±11.23)h and(118.35±12.57)h]respectively,which was displayed a statistical difference(P＜0.05）.Conclusion Combination of high-frequency oscillatory ventilation,pulmonary surfactant,and Milrinone on treating PPHN obtains a great effect by improving the total effectiveness rate and PASP and shortening the mechanical ventilation,which is worthy of application and promotion.
2018 Vol. 25 (7): 112-114 [Abstract] ( 138 ) HTML (27 KB)  PDF  (0 KB)  ( 28 )
115 Effect observation of laparoscopy combined with Leuprorelin in the treatment of endometriosis complicated with infertility
ZHANG Feng-qin
ObjectiveTo investigate the effect of laparoscopy combined with Leuprorelin in the treatment of endometriosis complicated with infertility.Methods From February 2014 to February 2017,clinical data from 80 endometriosis patients with infertility in our department were retrospectively analyzed.According to different treatment methods，they were evenly divided into control group(n=40,laparoscopic surgery alone)and observation group(n=40,laparoscopic surgery combined with Leuprorelin).The intraoperative bleeding volume,operation time,postoperative anal exhaust time,postoperative ambulation time,the levels of follicle stimulating hormone (FSH),estradiol(E2),luteinizing hormone(LH),and Kupperman menopause index(KMI)score before and after the operation,and clinical efficacy were observed in the two groups.Results The intraoperative bleeding volume,operation time,postoperative anal exhaust time,and postoperative ambulation time in the observation group were all lower than those in the control group,with statistical significance(P＜0.05).There was no great difference in FSH,E2,LH,or KMI score before surgery in both groups(P＞0.05).After surgery,the levels of FSH,E2,and LH in the two groups were all lower compared with those before surgery.The KMI score was higher.Meanwhile,the levels of FSH,E2,and LH were lower and KMI score was higher in the observation group than in the control group after surgery.The total clinical therapeutic effectiveness rate in the observation group was higher in comparison with that in the control group,with a statistical difference (P＜0.05).Conclusion Combination of laparoscopy and Leuprorelin in the treatment of endometriosis associated infertility patients has advantages of small trauma and quick recovery,reduce the levels of sex hormones,and improve clinical efficacy,which is worthy of clinical application and promotion.
2018 Vol. 25 (7): 115-117 [Abstract] ( 158 ) HTML (27 KB)  PDF  (0 KB)  ( 25 )
118 Effect analysis of disposable balloon cervical dilator on cervical ripening and induction of labor in term pregnancy
LIU Jia-ni
ObjectiveTo observe the effect of disposable balloon cervical dilator on cervical ripening and induction of labor in term pregnancy.Methods 74 pregnant women with indications of labor induction in our hospital from November 2015 to October 2017 were selected as the research objects.All of the pregnant women were randomly divided into balloon group and oxytocin group by random number table method,37cases in each group.Pregnant women in the two groups were given disposable balloon cervical dilator and oxytocin intravenous drip,respectively.The cervical maturity and induction of labor of the two groups were evaluated.Results Comparison of cervical Bishop score,34 cases(91.89%)in the balloon group were markedly effective,the total effective rate was 100.00%;12 cases(32.43%)in the oxytocin group were markedly effective,the total effective rate was 75.68%the difference was statistically significant(P＜0.05）.In the balloon group,23 cases(62.16%)started labor within 12 h,10 cases(27.03%)in 12-24 h,14 cases(37.84%)in the 12 h group and 13 cases(35.14%)in 12-24 h,the differences between the two groups were statistically significant(P＜0.05）.There was no significant difference between the two groups in the mode of delivery and the amount of postpartum 2 h bleeding (P＞0.05).There were no fetal distress and neonatal asphyxia in the two groups.Conclusion Disposable balloon cervical dilator for full-term pregnancy women can effectively promote cervical ripening，higher success rate of induction of labor.
2018 Vol. 25 (7): 118-120 [Abstract] ( 156 ) HTML (26 KB)  PDF  (0 KB)  ( 25 )
121 Effect observation of Estradiol valerate combined with Progesterone in prevention of intrauterine adhesions after induced abortion
ZHANG Bo-lan ；LIN Man ；QIU You-zhi
ObjectiveTo investigate the effect of Estradiol valerate combined with Progesterone in preventing uterine adhesions after induced abortion.Methods Clinical data of 62 induced abortion cases in our hospital from January 2016 to June 2017 were analyzed.According to the different treatment methods,they were divided into control group(n=30)and observation group(n=32).The postoperative amount of bleeding,bleeding time,time of menstruation return,endometrial thickness,abdominal pain and intrauterine adhesions were observed in the two groups.Results In the observation group,the postoperative amount of bleeding was(78.6±8.5)ml,bleeding time was(5.1±0.9)d,time of menstruation return was(19.4±3.5)d and the incidence of intrauterine adhesions was 6.3%,which were significantly lower than those in the control group([99.6±10.3]ml,[6.6±1.0]d,[27.3±4.1]d,and 23.3%).Accordingly.The severity of abdominal pain in the observation group was milder compared to that in the control group.The endometrial thickness was(9.9±0.2)mm,higher than that of the control group,(4.5±0.1)mm.The indexes mentioned above all differed statistically in the two groups(P＜0.05）.ConclusionEstradiol valerate combined with progesterone can obtain a great effect on preventing intrauterine adhesions after induced abortion,which is worthy of clinical application and promotion.
2018 Vol. 25 (7): 121-123 [Abstract] ( 131 ) HTML (24 KB)  PDF  (0 KB)  ( 32 )
124 The effects of the production process guided by new production standard on primipara and mother-infant ending
HUANG Li-li；LI Wen-min
ObjectiveTo discuss the effects of the production process guided by new production standard on primipara and Mother-infant ending.Methods Five hundred patients with primiparar were selected from June 2015 and June 2016 in our hospital,according to the random number table methods,all patients were divided into new standard group(250 cases)and old standard group(250 cases),old standard group was treated with the production process guided by old production standard,new standard group was treated with the production process guided by new production standard,compare two groups of deal with production,mother-infant ending.Results The first,second,and total production time of the new standard group was significantly higher than that of the old standard group,the differences were statistically significant(P＜0.05).The rate of cesarean section,postpartum hemorrhage and postpartum fever of the new standard group were significantly lower than that of the old group,the differences were statistically significant(P＜0.05).Neonatal asphyxiation rate and neonatal NICU rate of the new standard group and old standard group were basically the same,the differences were no statistically significant(P＞0.05).Conclusion Compared with the old production standard，the process of production process guided by new production standard can effectively improve the quality of birth process,and improve the outcome of primary mothers,does not increase the risk of adverse neonatal outcomes,it′s worth for further clinical promotion.
2018 Vol. 25 (7): 124-126 [Abstract] ( 146 ) HTML (26 KB)  PDF  (0 KB)  ( 29 )
127 Effect of Phloroglucinol combined with Lidocaine applied in patients with cervical tenacity to promote the dilatation of cervix
LIU Qiong
ObjectiveTo analyze the effect of Phloroglucinol combined with Lidocaine applied in patients with cervicaltenacity to promote the dilatation of cervix.Methods86 patients with dilatation of cervix in full term pregnancy treated in our hospital from February 2016 to October 2017 were selected as objects.The patients were divided into the control group and experimental group according to the random number table method,and each group had 43 cases.The patients in the control group were treated with Lidocaine,on the basis of which,the experimental group was treated with Phloroglucinol.The average time of active phase,average time of first production process,average blood loss of postpartum,neonatal asphyxia and mode of delivery in the two groups were analyzed.Results The average time of active phase and average time of first production process in the experimental group were shorter than those in the control group(P＜0.05).The rate of caesarean section in the experimental group (9.3%)was significantly lower than that of the control group(25.58%)(P＜0.05).There was no significant difference in the average blood loss of postpartum and the rate of eonatal asphyxia between the two groups(P＞0.05).Conclusion Phloroglucinol combined with Lidocaine applied in patients with cervical tenacity is helpful to promote the dilatation of cervix,accelerate the progress of the labor process,improve the quality of delivery,and it is safe and effective.
2018 Vol. 25 (7): 127-129 [Abstract] ( 156 ) HTML (26 KB)  PDF  (0 KB)  ( 27 )
130 Diagnostic value of MRI and X-ray on occupying breast lesions
FU Lan-lan；HU Xiao-dan；RONG Yang；YAO Bin
ObjectiveTo investigate the clinical value of MRI and X-ray photography in occupying breast lesions.Methods From December 2014 to December 2016,174 patients diagnosed as occupying breast lesions in Liaoyang Certral Hospital of Liaoning Province were selected as the subjects,and examined by MRI and X-ray,and finally verified by histopathology.There were 107 benign cases and 67 cases were malignant.The diagnostic value of MRI and X-ray on occupying lesions of breast were analyzed.Results Among benign occupying breast lesions,the diagnostic accuracy of MRI(100.0%)was higher than that of X-ray accounting (79.4%).Among malignant cases,the diagnostic accuracy of MRI(100.0%)was higher than that of X-ray accounting(77.6%).The overall diagnostic accuracy of MRI(100.0%)was much higher than that of X-ray(78.7%),the differences were statistically significant(P＜0.05).Conclusion Both MRI and X-ray can be used in the clinical diagnosis of occupying breast lesions,and the diagnostic value of MRI is higher after comparison,which is worthy of clinical promotion.
2018 Vol. 25 (7): 130-132 [Abstract] ( 154 ) HTML (26 KB)  PDF  (0 KB)  ( 27 )
133 Imagining features of multislice spiral CT in pulmonary ground-glass nodules in different pathological types
LI Mu-zi
ObjectiveTo study and explore the diagnostic value of multislice spiral CT in pulmonary ground-glass nodules in different pathological types.Methods From January 2015 to December 2016,a total of 100 patients with groundglass nodules in pulmonary alveoli displayed in pulmonary MSCT were retrospectively analyzed before surgery.According to pathological types,they were divided into pre-invasive lesion group (n=44),minimally invasive adenocarcinoma group(n=31)and invasive adenocarcinoma group(n=25).The indexes in each group were compared and analyzed.Results There were significant differences in size of focus,density,two-dimensional and three-dimensional ratio,edge burr shape and anterior vacuolus between infiltrative and microinvasive group (P＜0.05).The density of lesions in the infiltrating adenocarcinoma group was lower than that in the pre-invasive lesion group,and the differences in the degree of lesions and size between the two groups were statistically significant(P＜0.05).ConclusionAnalysis of MSCT imaging features of ground-glass nodules is of great importance for preoperative diagnosis and identification of micro-infiltrating adenocarcinoma,infiltrating adenocarcinoma and pre-invasive lung lesions.
2018 Vol. 25 (7): 133-135 [Abstract] ( 169 ) HTML (25 KB)  PDF  (0 KB)  ( 31 )
136 The application value of transvaginal ultrasound for patients with Ectopic of intrauterine contraceptive ring
SHEN Wen-Ying
ObjectiveTo study the application value of transvaginal ultrasound for patients with Ectopic of intrauterine contraceptive ring.Methods From March 2015 to July 2017,400 cases of healthy women in our hospital were selected as the research objects.At the same time,transvaginal ultrasound and abdominal ultrasonography were used to diagnose the heterotopic condition of intrauterine device in the patients.According to the situation of women′s menopause,the patients were divided into the childbearing age group (241 cases)and menopause group (159 cases).The transvaginal ultrasound diagnosis of ectopic IUD in the two groups of women′s situation were compared.Results The detection rate of transvaginal ultrasound in the diagnosis of ectopic intrauterine device was 11.75% (47/400),which was significantly higher than the transabdominal ultrasound of 7.50% (30/400).The detection rate of ectopic cervical canal by transvaginal ultrasound was 10.00% (40/400),which was significantly higher than the transabdominal ultrasound of 5.50%(22/400).The incidence of ectopic intrauterine device in childbearing age women was 7.05%(17/241),which was significantly lower than the menopausal women of 18.87%(30/159),the differences were statistically significant(P＜0.05).Conclusion The application of transvaginal ultrasound in diagnosis of ectopic IUD effect in women was superior than abdominal ultrasound,which can improve the accuracy of ectopic,and the risk of women of childbearing age occurrence of ectopic IUD in postmenopausal women is compared to lower,which is worthy of clinical attention.
2018 Vol. 25 (7): 136-138 [Abstract] ( 156 ) HTML (26 KB)  PDF  (0 KB)  ( 26 )
139 Clinical observation of Self-Made Yangxin Anshen Decoction in the treatment of women somnipathy
ZHU Fen-fang；HUANG De-lian；RUAN Guo-yong
ObjectiveTo explore the clinical effect of Self-Made Yangxin Anshen Decoction in the treatment of women somnipathy.Methods 60 cases clinical data of women somnipathy patients in our hospital from September 2015 to September 2017 were analyzed,who were divided into the treatment group and the control group by different treatment methods,30 cases in each group.The control group was given Alprazolam treatment,and the treatment group was treated with Self-Made Yangxin Anshen Decoction.The sleep quality score of the two group before treatment and aftert treatment and clinical effects were observed.Results There was no significant difference in the score of sleep quality,incubation period of sleep,sleep continuity,habitual sleep efficiency,sleep disorder,using sleeping drug,daytime dysfunction and the PSQI total score between the two groups before treatment(P＞0.05).The score of sleep quality,incubation period of sleep,sleep continuity,habitual sleep efficiency,sleep disorder,using sleeping drug,daytime dysfunction and the PSQI total score in the two groups after treatment were lower than those before treatment,the score of sleep quality,incubation period of sleep,sleep continuity,habitual sleep efficiency,sleep disorder,using sleeping drug,daytime dysfunction and the PSQI total score in the treatment group after treatment were lower than those in the control group,with significant difference(P＜0.05).The clinical treatment total effective rate of the treatment group was higher than that of the control group,the difference were statistical significance (P＜0.05).Conclusion The effect of Self-Made Yangxin Anshen Decoction in the treatment of women somnipathy is good,sleep quality improve obviously,it is worthy of promotion and application.
2018 Vol. 25 (7): 139-141 [Abstract] ( 156 ) HTML (26 KB)  PDF  (0 KB)  ( 26 )
142 Clinical efficacy observation of traction-based rotational bone-separation manipulation and traditional Chinese medicine therapy in the treatment of ulnar-radial fracture
ZHOU Tao-long
ObjectiveTo explore the clinical efficacy of traction-based rotational bone-separation manipulation and traditional Chinese medicine therapy in the treatment of ulnar-radial fracture.Methods 90 patients with ulnar-radial fracture treated from February 2015 to April 2016 in our hospital were selected as the subjects.The subjects were divided into the observation group and the control group according to the different therapies,45 cases in each group.The control group took the traction-based rotational bone-separation manipulation,the observation group took the tractionbased rotational bone-separation manipulation and traditional Chinese medicine therapy.The pain and swelling score,clinical effect and the incidence rate of postoperative complications were compared.Results Before treatment,the VAS points and swelling scores in the two groups were not significantly different(P＞0.05),after treatment,the VAS points and swelling scores for two groups were significantly different(P＜0.05).The total effective rate in the observation group(95.6%)was higher than that in the control group(77.8%),with significant difference(P＜0.05).The cure rate of malformation,the paralysis rate of superficial branch of radial nerve and infection rate in the observation group were significantly lower than that in the control group,with significant difference(P＜0.05).Conclusion The traction-based rotational bone-separation manipulation and traditional Chinese medicine therapy has an obvious effect in patients with ulnar-radial fracture,which can improve the VAS points and swelling scores and reduce the incidence rate of complications,it is worthy of clinical promotion and application.
2018 Vol. 25 (7): 142-144转148 [Abstract] ( 131 ) HTML (29 KB)  PDF  (0 KB)  ( 29 )
145 Clinical effect of Angelicae Sinensis Decoction for Supplementing Blood in the treatment of recessive hemorrhage of senile intertrochanteric fracture of femur after proximal femoral nail anti-rotation
XIE Qing ；YAN Jian-hua
ObjectiveTo explore the clinical effect of Angelicae Sinensis Decoction for Supplementing Blood in the treatment of recessive hemorrhage of senile intertrochanteric fracture of femur after proximal femoral nail anti-rotation(PFNA).Methods Altogether 60 elderly patients with intertrochanteric fracture of femur who were treated with PFNA from May 2014 to November 2016 in our hospital were selected and randomly divided into the study group and the control group,with 30 cases in each group.The study group was treated with Angelicae Sinensis Decoction for Supplementing Blood,while,the control group was treated with Ferrous Sulfate Tablets.The hemoglobin (Hb),hematocrit(Hct),hip joint function score (Harris score)and the incidence rate of complications of the two groups were observed and compared.Results The level of Hb and Hct of the two groups at pre-operative 1 day were not statistically significant(P＞0.05).The level of Hb and Hct of the study group at post-operative 5 and 7 days were significantly higher than those of the control group,with statistically significant difference (P＜0.05).The Harris score of the study group at post-operative 30 days and 3 months was significantly higher than that of the control group,with statistically significant difference(P＜0.05).There was no significant difference in the Harris score of the two groups after half a year(P＞0.05).The total incidence rate of complications of the study group was 10.0%,which was significantly lower than that of the control group(36.6%),with statistically significant difference(P＜0.05).Conclusion Angelicae Sinensis Decoction for Supplementing Blood has significant clinical effect in the treatment of senile intertrochanteric fracture of femur with recessive hemorrhage after PFNA,and can improve post-operative hidden blood loss,accelerate the recovery of hip joint functions with fewer complications and higher safety,which is worthy of clinical application and promotion.
2018 Vol. 25 (7): 145-148 [Abstract] ( 138 ) HTML (29 KB)  PDF  (0 KB)  ( 27 )
149 Clinical application of eugenic health education before pregnancy
HUANG Jin-xia；DU Hong-mei；ZHANG Lan
ObjectiveTo investigate the effect of eugenic health education before pregnancy on eugenics of pregnant women.Methods From January 2015 to January 2017,1800 pregnant women who received pregnancy test and whose pregnancy outcomes were known in our hospital were selected as research objects.According to whether or not to accept the health education before pregnancy,the subjects were divided into the receiving health education group(group A,869 cases)and the not receiving health education group(group B,931 cases).A questionnaire survey was carried out to know the awareness rate of eugenic knowledge,the exposure of risk factors before pregnancy and during pregnancy.And the mode of delivery and adverse pregnancy outcomes were compared.Results The awareness rate of eugenic knowledge in group A(95.51%)was higher than that in group B(89.04%),and the difference was statistically significant(P＜0.05).The probabilities of pregnant woman or her husband smoking(including second-hand smoke)and drinking in group A(1.15%,0.00%)were lower than those in group B(6.98%,1.72%),the differences were statistically significant(P＜0.05).There was no significant difference between the two groups in the probabilities of receiving potential electric radiation for longer than 8 h,medication before pregnancy and genetic diseases(P＞0.05).The cesarean delivery rate(32.68%)and vaginal birth rate(0.00%)in group A were significantly lower than group B(42.21%,0.64%),the natural births(66.40%)was significantly higher than that in group B(55.96%),the differences were statistically significant(P＜0.05).There was no statistically significant difference in the incidence of medical abortion and major defect induced labor between the two groups of pregnant women (P＞0.05).The incidence of macrosomia,premature and the birth defects in group A (3.34%,1.15%and 0.46%)were significantly lower than group B(8.38%,2.58%and 1.50%),the differences were statistically significant(P＜0.05),the incidence of low birth weight was compared between the two groups,and the difference was not statistically significant(P＞0.05).Conclusion Eugenic health education before pregnancy can improve the awareness of eugenic knowledge,change the bad habits of pregnant women,improve the delivery mode and reduce adverse pregnancy outcomes.
2018 Vol. 25 (7): 149-152 [Abstract] ( 140 ) HTML (30 KB)  PDF  (0 KB)  ( 24 )
153 Study of influence on social support between self-perception burden and health condition in the elderly with type 2 diabetes
LIU Hui-min
ObjectiveTo explore the influence on social support between self-perception burden and health condition in the elderly patients with type 2 diabetes.MethodsFrom August to September 2017,385 elderly patients with diabetes in the outpatient department of Jining hospital of traditional chinese medicine were selected as the research group,and 385 healthy people were selected as the control group during the same period.The social support rating scale(SSRS),the self-perceived burden scale(SPBS)and the simple health status scale(SF-36)were used to investigate and the scores of the two groups were compared.Results The total score of SSRS in the study group was (36.85±5.34)points,the total score of SPBS was(29.44±5.25)points,and the total score of SF-36 was(65.89±16.52)points.The total score of SSRS in the control group was(43.76±7.41)points,the total score of SPBS was(18.36±3.17)points,the total score of SF-36 was(77.75±17.35)points.The score of SSRS and SF-36 in the study group were significantly lower than that in the control group,while the SPBS score was significantly higher than that in the control group,the differences were statistically significant(t=14.844,35.450,9.714,P＜0.01).Pearson correlation analysis results showed that social support was negatively correlated with the burden of self-perception (r=-0.539,P＜0.01),social support was positively correlated with health condition (r=0.473,P＜0.01),the burden of self-perception was negatively correlated with health condition (r=0.388,P＜0.01).The result of the bivariate correlation analysis showed that there were correlation among social support,burden of self-perception and health condition.The result of the mediation effect analysis showed that the mediating effect the values of social support was 0.315,and the ratio of mediating effect to total effect was 0.454.Conclusion Social support is the influence factor of self-perception burden and health condition in the old age patients with type 2 diabetes.
2018 Vol. 25 (7): 153-156 [Abstract] ( 176 ) HTML (37 KB)  PDF  (0 KB)  ( 28 )
157 Effect of comprehensive nursing intervention on prevention of falls in domiciliary elderly people during hemodialysis
LI Xin-xia ；TAO Yan-ling； LUO Xuan-fen； CHEN Rui-juan
ObjectiveTo explore the effect of comprehensive nursing intervention on prevention of falls in elderly patients with hemodialysis (HD)at home.Methods 86 elderly HD patients who underwent continuous regular dialysis treatment in our hospital′s blood purification center from January 2012 to August 2016 were selected as the research object.They were divided into control group and observation group by random number table method,43 cases in each group.the control group was given conventional HD treatment and nursing,and the observation group was combined with comprehensive nursing intervention measures.The intervention period was 6 months.The incidence of falls,awareness of preventable falls,POMA scale score (reflecting balance and gait ability)and MFES score (reflecting fear of falls)were compared between the two groups.Results The incidence of falls in the observation group was significantly lower than that in the control group(P＜0.05).The awareness rate of fall prevention in the observation group was significantly higher than that in the control group(P＜0.05).The POMA and MFES scores of the observation group were significantly higher than those of the control group (P＜0.05).Conclusion The comprehensive nursing intervention can improve the correct understanding of fall and reduce the fear of fall,so as to effectively prevent falls.
2018 Vol. 25 (7): 157-159 [Abstract] ( 145 ) HTML (26 KB)  PDF  (0 KB)  ( 39 )
160 Appliction value of high quality nursing intervention in the treatment of patients with pulmonary tuberculosis
ZHANG Lan
ObjectiveTo investigate the impact of high quality nursing intervention on the psychological status and quality of life of patients with pulmonary tuberculosis.Methods 70 patients with pulmonary tuberculosis treated in our hospital from September 2016 to September 2017 were selected and divided into control group and observation group according to the different nursing intervention methods,with 35 cases in each group.The control group was treated with traditional nursing intervention,while the observation group was treated with high quality nursing intervention.The differences of psychological state and quality of life between the two groups were compared.Results The psychological state score of the observation group was lower than that of the control group,the difference was statistically significant(P＜0.05).The quality of life score of patients in the observation group was significantly higher than that in the control group,the difference was statistically significant(P＜0.05).Conclusion High quality nursing intervention has obvious clinical advantages in the psychological state and quality of life of patients with pulmonary tuberculosis compared with traditional nursing intervention,while helping patients recover health,it can further improve the psychological problems of patients.
2018 Vol. 25 (7): 160-162 [Abstract] ( 145 ) HTML (30 KB)  PDF  (0 KB)  ( 29 )
163 Effect of targeted psychological nursing on anxiety and depression of patients with laparoscopic endometrial cancer
XU Yan-yan；XU Ling-ling
ObjectiveTo investigate the effect of targeted psychological nursing on anxiety and depression of postoperative patients with laparoscopic endometrial cancer.Methods Sixty-two patients undergoing laparoscopic endometrial cancer surgery in our hospital from August 2015 to August 2017 were selected as the study subjects.the odd and even numbers of random hospitalized medical records were divided into conventional group and experimental group,with 31 cases in each group.The conventional group was given conventional nursing intervention,and the experimental group was combined with targeted psychological nursing intervention on this basis,and the nursing effect of the two groups was compared.Results There was no significant difference in SAS and SDS scores between the two groups before and after nursing(P＞0.05).The SAS and SDS scores of the two groups after nursing were lower than those before nursing the difference was statistically significant(P＜0.05).The SAS and SDS scores of the experimental group after nursing were lower than those of the conventional group the difference was statistically significant(P＜0.05).The quality of daily life score of the experimental group was higher than that of the conventional group,the difference was statistically significant(P＜0.05).The total satisfaction degree of nursing service in the experimental group was higher than that of the conventional group,and the difference was statistically significant(P＜0.05).Conclusion The targeted psychological nursing intervention in patients with laparoscopic endometrial cancer with satisfactory results,relieve negative emotions,improve postoperative quality of life,the promotion of high value.
2018 Vol. 25 (7): 163-165 [Abstract] ( 159 ) HTML (27 KB)  PDF  (0 KB)  ( 32 )
166 The Treatment Effect of Migraine Persistent StatePatients with Comprehensive Nursing Intervention
SHAN Shu-zhen； LI Yan-ling ；TANG Wei
ObjectiveTo discussthe treatment effect of migraine persistent state patients with comprehensive nursing intervention.Methods From June 2014 to June 2016,60 patients with migraine in our hospital were randomly divided into control group and experimental group,30 cases in each group.The control group was given conventional nursing on the basis of conventional medicine treatment,and the experimental group was given comprehensive nursing on the basis of conventional medicine treatment.The average time and degree of headache were measured by SAS and SDS.the serum level of 5-HT was measured by ELISA.Results The pain score of VAS of the experimental group was lower than that of the control group(P＜0.05),and the time of headache attack was shorter than that of the control group(P＜0.05).SAS and SDS score of the experimental group were lower than those of the control group(P＜0.05).There was no significant difference in serum 5-HT between the two groups at admission(P＞0.05).After 7 days,the serum 5-HT of the experimental group was higher than that of the control group(P＜0.05).Conclusion Comprehensive nursing interventionwas deserved to be widely applied in clinic as it could improve the clinical curative，relieve anxiety and depression，alleviate symptoms of migraine persistent state patients.
2018 Vol. 25 (7): 166-168 [Abstract] ( 156 ) HTML (30 KB)  PDF  (0 KB)  ( 28 )
169 The application effect of comprehensive nursing in hemodialysis after PCI in patients with renal disease combined with coronary heart disease
LI Ying-dan
ObjectiveTo explore the effect of comprehensive nursing in hemodialysis after percutaneous coronary intervention(PCI)in patients with renal disease combined with coronary heart disease.Methods One hundred and four patients with kidney disease and coronary heart disease admitted to our hospital from February 2016 to February 2017 were randomly divided into study group(comprehensive nursing)and control group(conventional nursing),52 cases in each group.All patients underwent symptomatic treatment after admission,selective PCI and hemodialysis after improvement.According to the principle of random.The nursing effect of the two groups was compared.Results After intervention,the quality of life score(SF-36)of the study group was better than that of the control group,the difference was statistically significant(P＜0.05).The score of symptom checklist 90(SCL-90)in the study group was better than that in the control group(P＜0.05).The total incidence of complications in the study group was lower than that in the control group,and there was no one case with two or more complications,the difference was statistically significant(P＜0.05).Conclusion The effect of comprehensive nursing in hemodialysis after PCI in patients with renal disease combined with coronary heart disease is more ideal.
2018 Vol. 25 (7): 169-171 [Abstract] ( 156 ) HTML (26 KB)  PDF  (0 KB)  ( 29 )
172 Application effect of nursing intervention in ICU patients performed with bedside alveolar lavage under fiber bronchoscope
DING Xin-ran
ObjectiveTo study the effect of nursing intervention on bedside alveolar lavage under fiber bronchoscope in intensive care unit(ICU)in our hospital.Methods From March 2015 to April 2017,82 patients who received bronchoalveolar lavage by fiberoptic bronchoscopy in ICU were selected as the subjects,and divided into study group and control group,41 cases in each group.Patients in the control group were given routine care,and patients in the study group were given comprehensive nursing intervention.The time of ventilator use,arterial blood gas analysis index,complications,extubation time and hospital stay were compared between the two groups.Results Before nursing,there was no significant difference in heart rate and blood oxygen partial pressure between the control group and the study group (P＞0.05).After nursing,the blood gas analysis indexes of the two groups were improved,and the improvement degree of the study group was significantly higher than that of the control group,the difference was statistically significant(P＜0.05);The use time and hospitalization time of ventilator in the study group were shorter than those in the control group,the difference was statistically significant(P＜0.05).The total incidence of complications in the study group was lower than that in the control group (P＜0.05).Conclusion The comprehensive nursing intervention for patients with bronchofibroscopic lavage can reduce the use time of ventilator,improve blood gas,decrease the incidence of complications and shorten the hospital stay in a favorable nursing effect.
2018 Vol. 25 (7): 172-174 [Abstract] ( 162 ) HTML (27 KB)  PDF  (0 KB)  ( 23 )
175 The application of family centered nursing care in the nursing of very low birth weight infants
LIANG Jun；CUI Ni
ObjectiveTo explore the application of family centered nursing model in the nursing of very low birth weight infants.Methods From may 2016 to may 2017,70 cases of very low birth weigh infants were randomly divided into control group and observation group according to the birth order,35 cases in each group.The observation group was given family-centered nursing mode,while the control group was given routine nursing.The feeding status,growth and development,nursing satisfaction,outpatient visit rate and readmission rate within 1 month after discharge were compared between the two groups.Results The daily milk intake of children in the observation group was higher than that in the control group (P＜0.05).The recovery time of birth weight and total intestinal nutrition of children in the observation group were shorter than those in the control group (P＜0.05).The pure breast feeding rate of children in the observation group was significantly higher than that in the control group(P＜0.05).The feeding intolerance rate in the observation group was significantly lower than that in the control group,the difference was statistically significant(P＜0.05).After intervention,the growth and development of body length,body weight and head circumference in the observation group were better than those in the control group,the difference was statistically significant(P＜0.05).The growth and development of body length,body weight and head circumference of the observation group after intervention were better than those before intervention,the difference was statistically significant(P＜0.05).The nursing satisfaction of the parents of the observation group was significantly higher than that of the control group,the difference was statistically significant(P＜0.05).Within 1 month after discharge,the outpatient visit rate and readmission rate of the observation group were significantly lower than those of the control group,the difference was statistically significant(P＜0.05).Conclusion The family centered care model can effectively improve the feeding status of very low birth weight infants,increase the breast-feeding rate,improve the level of growth and development of children,reduce the discharge rates of outpatient visits and hospitalization rate,improve nursing satisfaction,is worthy of clinical application.
2018 Vol. 25 (7): 175-177转181 [Abstract] ( 177 ) HTML (29 KB)  PDF  (0 KB)  ( 31 )
178 Application of different temperature intervention methods in continuous blood purification for eldly patients with acute renal failure
WANGLi-li；LIU Li； MENG Kun
ObjectiveTo explore the effect of two different body temperature interventions on the prevention of hypothermia during CBP treatment in elderly patients with renal failure.Methods Seventy-six elderly patients with acute renal failure treated with CBP in our hospital from January to December 2017 were randomly divided into control group and observation group with 38 cases in each group.The control group was treated with conventional nursing method and quilt covering method.At the beginning of CBP treatment,the observation group was treated with inflation heating blanket.The heart rate,mean arterial pressure,rectal temperature and hypothermia during CBP treatment were recorded at 1,2,4,8 h and 12 h after CBP treatment.Results There was no significant difference in heart rate and mean arterial pressure between the observation group and the control group at 1,2,4,8 h and 12 h after CBP treatment(P＞0.05).There was no significant difference in heart rate and mean arterial pressure between the two groups at 2,4,8,12 h after CBP treatment and 1 h after CBP treatment(P＞0.05).The rectal temperature in observation group was higher than that in control group at 1,2,4,8 h and 12 h after CBP treatment(P＜0.05).The rectal temperature of two groups of patients at 2,4,8 h and 12 h after CBP treatment was lower than that at 1 h after CBP treatment(P＜0.05).The incidence of hypothermia in the observation group was lower than that in the control group at 1,2,4,8 h and 12 h after CBP treatment,and the longer the treatment time,the greater the difference in the incidence of hypothermia.There was no significant difference in the incidence of hypothermia at 1 and 2 h after treatment between the observation group and the control group (P＞0.05).the incidence of hypothermia at 4,8 h and 12 h after treatment between the observation group and the control group was statistically significant(P＜0.05).Conclusion Forced-Air Warming blanket is an effective body temperature intervention method during CBP therapy which can reduce the incidence of hypothermia.
2018 Vol. 25 (7): 178-181 [Abstract] ( 168 ) HTML (32 KB)  PDF  (0 KB)  ( 27 )
182 The application value of emotional nursing combined with psychological nursing in children with appendicitis in patients
WENG Mei-qiong
ObjectiveTo investigate the application value of emotional nursing combined with psychological nursing in children with appendicitis in patients.Methods 100 cases of appendicitis in our hospital from may 2016 to April 2017 were selected as the research object,and were divided into control group and observation group by random number table method,with 50 cases in each group.The control group was given routine clinical care.The experimental group was given emotional nursing combined with psychological care on the basis of routine clinical care.The improvement time of clinical symptoms,hospitalization time,postoperative recovery and SDS,SAS score before and after nursing were compared between the two groups.Results The clinical total effective rate of the experimental group was significantly higher than that of the control group,the difference was statistically significant(P＜0.01);The ambulation time,anal exhaust time and hospitalization time of the experimental group were shorter than those of the control group the difference was statistically significant(P＜0.05).The degree of nursing cooperation and family satisfaction of the experimental group were better than those of the control group(P＜0.05).There was no significant difference in SDS and SAS score between the two groups(P＜0.05).After nursing,SDS and SAS scores of the two groups were lower than those before nursing,and the observation group was better than the control group,the difference was statistically significant(P＜0.01).Conclusion The application of emotional nursing combined with psychological nursing in children with appendicitis in children can alleviate the negative emotions,improve the matching degree of treatment,shorten the time of hospitalization,improve the degree of satisfaction to nursing work,with a high clinical value.
2018 Vol. 25 (7): 182-184 [Abstract] ( 147 ) HTML (28 KB)  PDF  (0 KB)  ( 29 )
185 Application effect of psychological nursing in patients with cerebrovascular intervention
WANG Wei
ObjectiveTo carry out psychological nursing on preoperative anxiety of patients with cerebrovascular intervention,and to explore and study its nursing effect.Methods From January to September 2017,120 patients with cerebral vascular interventional therapy in our hospital were selected and divided into control group and study group by coin throwing (positive into the study group,negative into the control group),60 cases in each group.The study group was given psychological care,and the control group was given routine care.after that,the anxiety scores of the two groups of patients before and after nursing were investigated,and the nursing satisfaction of the patients was investigated.Results The nursing satisfaction of the study group was higher than that of the control group,the difference was statistically significant(P＜0.05).The anxiety score of the study group after nursing was lower than that of the control group,the difference was statistically significant(P＜0.05).Conclusion If a cerebrovascular intervention patient occurring with preoperative anxiety,thepsychological nursing measures can be implemented to help the patient improve anxiety as well as the prognosis,and maintain a good nurse-patient relationship.
2018 Vol. 25 (7): 185-187 [Abstract] ( 166 ) HTML (24 KB)  PDF  (0 KB)  ( 39 )
188 The effect of holistic nursing extension services in improving the quality of life of elderly patients with chronic diseases
YANG Yi-miao ；WEI Dao-hua ；LIN Xiao-min
ObjectiveTo observe the elderly patients with chronic diseases(high blood pressure)to holistic nursing extension services program after care of the situation.Methods Fifty elderly patients with hypertension in our hospital from January 12,2015 to January 12,2017 were selected and randomly divided into control group and observation group,with 25 cases in each group.The control group was given routine education and guidance nursing,and the observation group was given holistic nursing extension services.the compliance and quality of life of blood pressure control were compared between the two groups.Results The compliance of blood pressure control in the observation group was higher than that in the control group at 3 months and 6 months,the difference was statistically significant(P＜0.05).The quality of life data of the observation group were higher than that of the control group,the difference was statistically significant(P＜0.05).Conclusion The patients with hypertension in elderly patients with chronic diseases,after taking the holistic nursing extension services,the patient′s blood pressure has been significantly controlled,not only can significantly improve compliance,but also can effectively improve the quality of life of patients.
2018 Vol. 25 (7): 188-190 [Abstract] ( 170 ) HTML (26 KB)  PDF  (0 KB)  ( 29 )
191 Application effect of individualized nursing intervention in patients with schizophrenia
CONG Su-lan
ObjectiveTo analyze the psychological characteristics of patients with schizophrenia and to explore the effective measures of nursing.Methods 78 patients with schizophrenia treated in our hospital from June to December 2016 were selected,all of them were first onset patients,the patients were divided into observation group (40 cases)and control group (38 cases)by simple randomization.Both groups were given conventional antipsychotic therapy and nursing intervention after admission,after admission,both groups were given conventional antipsychotic drugs treatment and nursing intervention,the observation group on this basis,according to the psychological characteristics of patients in the early stage of admission to personalized nursing measures.After 3 months of nursing intervention,BPRS,SDSS scores and patients'satisfaction with nursing were compared between the two groups.Results There was no significant difference in BPRS and SDSS scores between the two groups(P＜0.05).After 3 months of intervention,the bprs and SDSS scores of the observation group were significantly lower than those of the control group,the difference was statistically significant(P＜0.05),the total satisfaction of the observation group was significantly higher than that of the control group,the difference was statistically significant(P＜0.05).Conclusion There are many psychological characteristics such as rebellious psychology,uncooperative,irritable and pessimistic in the first stage of admission of schizophrenic patients.Care to establish mutual trust relationship,first for different types of schizophrenia patients with personalized nursing measures,should also pay attention to the cognitive therapy,social skills training and family nursing intervention nursing interventions on the use of technology.
2018 Vol. 25 (7): 191-193 [Abstract] ( 158 ) HTML (27 KB)  PDF  (0 KB)  ( 27 )
194 Continuous nursing to improve knowledge of hypoglycemia in diabetes patients in middle-aged and elderly patients
QU Jin-qi
ObjectiveTo study the effect of continuous nursing on improving the knowledge of hypoglycemia in middleaged and elderly patients with diabetes and the quality of life.Methods Forty middle-aged and elderly patients with diabetes diagnosed in our hospital from February 2014 to February 2016 were selected as the study subjects.continuous nursing measures were implemented after discharge.the knowledge of hypoglycemia and quality of life of patients before and after nursing intervention were compared six months later.Results After continuous nursing,the patients'understanding of the etiology,symptoms and response measures of hypoglycemia was significantly better than that before nursing,the difference was statistically significant(P＜0.05).After continuous nursing,the quality of life of patients was significantly better than that before nursing,the difference was statistically significant(P＜0.05).Conclusion The continuous nursing care for middle-aged and elderly diabetic patients can improve the knowledge of hypoglycemia in middleaged and elderly diabetic patients,cultivate healthy life habits and improve the quality of life,which deserves to be used in clinical promotion.
2018 Vol. 25 (7): 194-196 [Abstract] ( 161 ) HTML (26 KB)  PDF  (0 KB)  ( 27 )
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