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| Effect observation of laparoscopy combined with Leuprorelin in the treatment of endometriosis complicated with infertility |
| ZHANG Feng-qin |
| Department of Gynecology and Obstetrics,Maternal and Child Health Care Hospital of Dingtao District in Heze City,Shandong Province,Heze 274000,China |
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Abstract ObjectiveTo investigate the effect of laparoscopy combined with Leuprorelin in the treatment of endometriosis complicated with infertility.Methods From February 2014 to February 2017,clinical data from 80 endometriosis patients with infertility in our department were retrospectively analyzed.According to different treatment methods，they were evenly divided into control group(n=40,laparoscopic surgery alone)and observation group(n=40,laparoscopic surgery combined with Leuprorelin).The intraoperative bleeding volume,operation time,postoperative anal exhaust time,postoperative ambulation time,the levels of follicle stimulating hormone (FSH),estradiol(E2),luteinizing hormone(LH),and Kupperman menopause index(KMI)score before and after the operation,and clinical efficacy were observed in the two groups.Results The intraoperative bleeding volume,operation time,postoperative anal exhaust time,and postoperative ambulation time in the observation group were all lower than those in the control group,with statistical significance(P＜0.05).There was no great difference in FSH,E2,LH,or KMI score before surgery in both groups(P＞0.05).After surgery,the levels of FSH,E2,and LH in the two groups were all lower compared with those before surgery.The KMI score was higher.Meanwhile,the levels of FSH,E2,and LH were lower and KMI score was higher in the observation group than in the control group after surgery.The total clinical therapeutic effectiveness rate in the observation group was higher in comparison with that in the control group,with a statistical difference (P＜0.05).Conclusion Combination of laparoscopy and Leuprorelin in the treatment of endometriosis associated infertility patients has advantages of small trauma and quick recovery,reduce the levels of sex hormones,and improve clinical efficacy,which is worthy of clinical application and promotion.
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