降钙素在老年股骨颈骨折双极股骨头置换术后的应用效果

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Abstract ObjectiveTo investigate the effect of calcitonin in the elderly patients with femoral neck fracture after bipolar femoral head replacement.Methods A total of 59 elderly patients with femoral neck fracture who were treated with bipolar femoral head replacement in our hospital from January 2013 to June 2015 were selected as the subjects,and randomly divided into calcitonin group and control group,with 29 cases in calcitonin group and 30 cases in control group.Calcitonin was used for more than one year after the operation,and the control group was not treated with calcitonin after the replacement of the femoral head.The Harris hip scores,the hip bone density of the healthy side,the risk of re-fracture and the postoperative complications between the two groups were observed.Results All 59 patients were followed up for at least 2 years.There were no complications such as surgical incision infection,pulmonary embolism,joint dislocation and pulmonary infection in the two groups.1 case of deep vein thrombosis occurred in the control group after operation.There was no re-fracture in the calcitonin group,and 1 case in the control group were complicated with distal radius fractures at 11 months after operation.The T value of the hip bone density in the calcitonin group at 6 months,1 year and 2 years after the operation was statistically significant compared with the control group (P＜0.05).The Harris hip scores in the calcitonin group were better than those in the control group at 6 months,1 year and 2 years after operation,the differences were statistically significant(P＜0.05).Conclusion The combined use of calcitonin in elderly patients with femoral neck fracture after bipolar femoral head replacement is beneficial to improve bone mineral density and early recovery of hip joint function.

Key words： Femoral neck fracture Calcitonin Femoral head replacement Osteoporosis

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	ZHU Guang-ming
	YAN Bin

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ZHU Guang-ming,YAN Bin. Effectiveness of Application of Calcitonin in the elderly patients with femoral neck fracture after bipolar femoral head replacement[J]. 中国当代医药, 2018, 25(7): 96-99.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I7/96

[3]	徐志文，陈有芬，朱家骏，等.降钙素联合锁定钢板治疗老年肱骨近端骨折的疗效[J].中国老年学杂志，2016，12（36）：5938-5940.
[5]	刘昊楠，贺良，张贵林，等.空心钉内固定和人工股骨头置换术治疗老年移位型股骨颈骨折的疗效观察[J].中国矫形外科杂志，2016，24（24）：2228-2232.
[6]	张英泽.股骨颈骨折治疗方案选择策略与进展[J].中国骨伤，2015，28（9）：781-783.
[8]	叶向阳，王华磊，赵玉果，等.一期全髋置换与股骨头置换修复老年股骨颈骨折：髋关节功能与并发症的Meta分析[J].中国组织工程研究，2016，20（22）：3328-3336.
[1]	Bergstrom U，Bjornstig U，Stenlund H，et al.Fracture mechanisms and fracture pattern in men and woman aged 50 years and older：a study of a 12-year population-based injury register，U mea，Sweden[J].Osteoporos Int，2008，19（9）：1267-1273.
[2]	Napoli N，Schwartz AV，Palermo L，et al.Risk factors for subtrochantericanddiaphysealfractures：thestudyofosteoporotic fractures[J].J Clin Endocrinol Metab，2013，98（2）：659-667.
[4]	Gjertsen JE，Vinje T，Engesaeter LB，et al.Internal screw fixation compared with bipolar hemianhroplasty for treatment of displaced femoral neck fractures in elderly patients[J].J Bone Joint Surg Am，2010，92（3）：619-628.
[7]	Zi-Sheng A，You-Shui G，Zhi-Zhen J，et al.Hemiarthroplasty vs primary total hip arthroplasty for displaced fractures of the femoral neck in the elderly：a meta-analysis[J].J Arthroplasty，2012，27（4）：583-590.
[9]	石波，谢明锐，李宗原.双极股骨头置换中应用带线铆钉修复关节囊治疗高龄患者股骨颈骨折[J].中国骨伤，2017，30（3）：313-317.
[10]	Yang B，Liu X，Yin XM，et al.Bipolar versus unipolar hemiarthroplasty for displaced femoral neck fractures in the elder patient：a systematic review and meta-analysis of randomized trials[J].Eur J Orthop Surg Tranmatol，2015，25（3）：425-433.
[11]	Chesnut CH，Azria M，Silverman S，et al.Salmon calcitionin：a review of current and future therapeutic indications[J].Osteoporos Int，2008，19（4）：479-491.
[12]	Bulbul M，Esenyel CZ，Esenyel M，et al.Effects of calcitonin on the biomechanics，histopathology，and radiography of callus formation in rats[J].J Orthop Sci，2008，13（2）：136-144.
[13]	Wei J，Wang J，Gong Y，et al.Effectiveness of combined salmon calcitonin and aspirin therapy for osteoporosis in ovariectomized rats[J].Mol Med Rep，2015，12（2）：1717-1726.
[14]	Atbinici H，Sipahioglu S，Aksoy N，et al.Effects of salmon calcitonin treatment on serum and synovial fluid bone formation and resorption markers in osteoporosis patients[J].Acta Orthop Traumatol Turc，2015，49（2）：160-165.
[15]	刘振宇.降钙素增强双膦酸盐对绝经后骨质疏松患者慢性腰背痛缓解及生活质量改善的作用[J].中国组织工程研究，2016，20（33）：4899-4904.
[16]	陈宝，陈国俊，龚遂良，等.降钙素在老年不稳定型股骨转子间骨折应用[J].中华骨科杂志，2014，34（1）：24-28.
[17]	陈有芬，沈晓霞，叶剑平，等.降钙素促进老年患者复杂性胫骨平台骨折锁定钢板治疗后的功能恢复[J].浙江医学，2016，38（6）：389-392.
[18]	Arnala IO.Salmon calcitonin （Miacalcic ns 200 IU）in prevention of bone loss after hip replacement[J].Scand J Surg，2012，101（4）：249-254.
[19]	Iwamoto N，Inaba Y，Kobayashi N，et al.The effectiveness of mono or combined osteoporosis drug therapy against bone mineral density loss around femoral implants after total hip arthroplasty[J].J Bone Miner Metab，2014，32（5）：539-544.