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2017 Vol. 24, No. 34
Published: 2017-12-08
 
 
4 Quality control of Shanzhuang Jiangzhi Tablets and process study of its film-coating
HUANG Fei-long；HOU Chao；WANG Cheng；ZHANG Yu-jing；SONG Jia
ObjectiveTo establish a method for the content determinations of Aurantio-obtusin and Chrysophanol in Shanzhuang Jiangzhi Tablets and test its film-coating technology.MethodsThe high performance liquid chromatography method (HPLC)was used to determine the content of Aurantio-obtusin and Chrysophanol in Shanzhuang Jiangzhi Tablets.The octadecylsilane chemically bonded silica was used as the filling agent in chromatographic column.The mobile phase was acetonitrile 0.1%phosphoric acid solution(gradient elution)at a flow velocity of 1.0 ml/min.The detection wavelength was 284 nm and sample size was 10 μl.At premise of not changing the original extraction process,the film-coating technology of Shanzhuang Jiangzhi Tablets was tested.ResultsThe great linear relationships were obtained when Aurantio-obtusin and Chrysophanol being ranged from 4.11-102.80 μg/ml and 6.82-170.40 μg/ml respectively(r=0.9998,r=0.9997).The precision and stability test were both good.The RSD value of average recovery rates were 1.47%and 0.81%respectively.Spray-drying was optimized for the concrete drying of film-coating tablets.ConclusionThe method is accurate,sensitive and simple,and can be used for the content determinations of Aurantio-obtusin and Chrysophanol in Shanzhuang Jiangzhi Tablets.The film-coating process can be used in large-scale production.
2017 Vol. 24 (34): 4-7转11 [Abstract] ( 215 ) HTML (42 KB)  PDF  (0 KB)  ( 44 )
8 Reverse phase high performanceliquid chromatography analysis of Tadalafil in Orodispersible Films
ZHAO Zong-liang；GAO Ying；CAO Qing-ri
ObjectiveTo establish ananalytical method of reverse phase high performance liquid chromatography (RPHPLC)to analyze the Tadalafil(TDF)content in Orodispersible Films(ODFs).MethodsTDF-loaded ODFs with a loading capacity up to 20 mg TDF in an area of 2 cm×3 cm were prepared using a solvent casting method.The chromatographic column was Cosmosil 5 C18-MS-Ⅱ (4.6×250 mm,5 μm)and mobile phase of acetonitrile-0.1%Trifluoroacetic Acid (44:56)were used,the detection wavelength was set at 285 nm,the flow rate was 1.0 ml/min,the column temperature was maintained at 40℃ and the injection volume was 20 μl.The drug content in TDF-loaded ODFs was analyzed.ResultsThe TDF concentration range with good linear relationship was 0.8-40 μg/ml,R2=0.9998.The RSD of intra-day was in the range of 0.002%-0.968%,RSD of inter-day was in the range of 1.22%-1.83%.Mean result of recovery rate was 99.22%.The limit of quantitation(LOQ)was 0.902 ng and the limit of detection(LOD)was 0.271 ng.The drug content of TDF-loaded ODFs was 96.43%.ConclusionThe RP-HPLC method of TDF showed high specific,good precision,recovery rate and stability.This method is suitable for thedetermination of drug content of TDF-loaded ODFs.
2017 Vol. 24 (34): 8-11 [Abstract] ( 191 ) HTML (42 KB)  PDF  (0 KB)  ( 45 )
12 Study on the correlation between lipid comprehensive index and left atrial size in patients with essential hypertension
CHEN Liang ；LIANG Shu
ObjectiveTo investigate the correlation between lipid comprehensive index and left atrial size in patients with essential hypertension.MethodsFrom May 2014 to April 2016,200 patients with essential hypertention whose data were complete in our hospital were selected.According to the results of transthoracic echocardiography,the patients were divided into case atrial enlargement group(70 cases)and left atrial normal group(130 cases),The renal function,blood lipid,blood pressure,fasting blood glucose,blood lipid comprehensive index and other indicators were measured and statistically analyzed.Spearman was used for correlation analysis,and multivariate linear regression was used for the analysis of relevant factors of left atrial enlargement.ResultsIn blood lipid comprehensive index between the two groups,the difference was statistically significant(P＜0.05).Spearman correlation analysis showed the blood lipid comprehensive index was positively correlated with the left atrial size(r=0.418,P＜0.001),and the multivariate linear regression analysis showed the blood lipid comprehensive index remained positively correlated with left atrial size(β=0.394,95%CI:0.133,0.697;P=0.001).ConclusionIn the patients with essential hypertension,the lipid comprehensive index is positively correlated with the left atrial size and is a risk factor for left atrial enlargement.
2017 Vol. 24 (34): 12-15 [Abstract] ( 212 ) HTML (37 KB)  PDF  (0 KB)  ( 38 )
16 Research progress of hemorrhagic transformation after intravenous thrombolysis in ischemic stroke
ZHOU Hui-fang ；LI Qin
With the increasing population aging in our country,stroke harm to our national have become increasingly prominent,which has the characteristics of high incidence rate,high recurrence rate,high disability rate,high mortality rate and economic burden,has become the first cause of death in our country.With the development of intravenous thrombolysis in ischemic stroke,the risk factors and predictors of hemorrhagic transformation have attracted much attention.This paper reviewed the clinical risk factors and forecasting index of hemorrhagic transformation in acute ischemic stroke after intravenous thrombolysis.The different clinical risk factors and application value of forecasting index were analyzed,in order to clinicians on whether patients with acute ischemic stroke for intravenous thrombolysis for rapid decision-making and provide for the prediction of the risk of intracerebral hemorrhage after thrombolysis.
2017 Vol. 24 (34): 16-18 [Abstract] ( 224 ) HTML (34 KB)  PDF  (0 KB)  ( 40 )
19 Exploration of clinical application and improvement of sural neurovascular flap
HONG Qiao-yang ；CHEN Jian-rui ；ZHANG Xue-min ；XU Geng-tian； GUO Yue-yue
ObjectiveTo explore the clinical application of sural neurovascular retrograde flap,to summarize and improve the surgical method,and to further improve the survival of the flap.Methods60 cases of forefoot skin tissue defect caused by trauma from February 2015 to January 2017 in our hospital were selected as the subjects,according to the different surgical methods,all patients were divided into the observation group and the control group,30 cases in each group.The observation group was used modified sural neurovascular nutrition flap repair method,the control group was used traditional sural neurovascular nutrition flap repair method.The clinical efficacy,wound healing time and complications occurred were observed between the two groups.ResultsThe total effective rate of the observation group was 100.0%,which was higher than 86.7%of the control group,the difference was statistically significant (P＜0.05).The wound healing time of the observation group was significantly lower than that in the control group,with significant difference (P＜0.05).The incidence of complications of the observation group was 0.0%,which was lower than 16.7%of the control group,the difference was statistically significant(P＜0.05).ConclusionThe sural neurovascular nutrition flap is an ideal method for repairing the defects of the forefoot skin tissue defect with the tendon,bone and blood vessels,it is more beneficial to the survival of the flap and improve the recovery effect through the improving surgical method.
2017 Vol. 24 (34): 19-21转27 [Abstract] ( 184 ) HTML (37 KB)  PDF  (0 KB)  ( 50 )
22 Application of oxygen supply within the Venturi mask in AIDS complicated with Pneumocystis carinii pneumonia
KANG Chun-hua；PENG Fu-mei；LIU Dan-ping
ObjectiveTo investigate the Venturi mask in the treatment of patients with AIDS complicated with Pneumocystis carinii pneumonia.Methods64 patients with AIDS complicated with Pneumocystis carinii pneumonia in our hospital from September 2013 to May 2017 were selected as the subjects,and randomly divided into the control group and the observation group,32 cases in each group.The control group was given normal nasal catheter oxygen therapy,the observation group was given Venturi mask for oxygen.The improvement of arterial partial pressure of oxygen(PaO2),arterial oxygen saturation (SpO2),comfort degree of oxygen therapy and nasal mucosa dryness were compared between the two groups at different time points.ResultsThe level of PaO2and SpO2in the observation group were significantly higher than those in the control group,the differences were statistically significant(P＜0.05).The incidence rate of oxygen therapy and discomfort,dry nasal mucosa in the observation group was significantly lower than those in the control group,the differences were statistically significant(P＜0.05).ConclusionThe application effect of the Venturi mask in the treatment of AIDS patients complicated with Pneumocystis carinii pneumonia is better,which can effectively improve PaO2and SpO2in patients with hypoxemia and so on.
2017 Vol. 24 (34): 22-24 [Abstract] ( 182 ) HTML (37 KB)  PDF  (0 KB)  ( 49 )
25 Clinical effect comparison of rectal mucosa resection via anal stapling and transrectal closed repair in the treatment of rectocele
LIU Li-song ；SHENG Shou-yin▲
ObjectiveTo compare the clinical effect of rectal mucosa resection via anal stapling and transrectal closed repair in the treatment of rectocele.MethodsFrom January 20 in 2016 to January 20 in 2017,40 patients with rectocele treated in our hospital were enrolled and evenly divided into the control group and the observation group by computer matching.In the control group,transrectal closed repair was used,while in the observation group,rectal mucosa resection via anal stapling was adopted.The clinical indicators and therapeutic effect were compared between the two groups.ResultsThe operation time and hospital stay in the observation group were shorter than those in the control group,and the amount of bleeding and frequency of using analgesic drugs were less compared with the control group,with significiant differences(P＜0.05).The total effectiveness rate in the observation group (95.00%)was higher than that in the control group (70.00%),with significiant difference (P＜0.05).ConclusionApplication of rectal mucosa resection via anal stapling can effectively improve patient′s clinical indexes,with remarkable effect,which is worthy of study.
2017 Vol. 24 (34): 25-27 [Abstract] ( 195 ) HTML (31 KB)  PDF  (0 KB)  ( 41 )
28 Effect study of laparoscopic surgery on adult patients with inguinal hernia
RAN Fu-lin ；CHEN Xiao
ObjectiveTo investigate the effect of laparoscopic surgery in adult patients with inguinal hernia.MethodsA total of 266 cases of inguinal hernia treated in our hospital from January 2012 to January 2017 were selected as the subjects,among them,126 patients were treated with laparoscopic peritoneal prefovement repair were selected as the TAPP group,90 patients with complete peritoneal repair were selected as the TEP group.The operative time,postoperative hospital stay,postoperative VAS score,and complication rate and recurrence rate were compared between the two groups.ResultsThe operation time of the TEP group ([45.5±9.8]min)was shorter than that of the TAPP group ([65.3±10.5]min),the differences were statistically significant(P＜0.05).There was no significant difference in the hospitalization time between the two groups(P＞0.05).There was no significant difference in the VAS scores of the patients at admission and postoperative 24 h between the two groups(P＞0.05).The incidence of abnormalities,serum swollen,intestinal paralysis and urinary retention in the TEP group were 5.6%,8.9%,1.1%,8.9%,the incidence of abnormalities,serum swollen,intestinal paralysis and urinary retention in the TAPP group were 8.7%,11.1%,2.4%,11.9%,the difference was statistically significant(P＜0.05).The recurrence rate within 6 months after operation in the TEP group was 8.89%,which was higher than that in the TAPP group(3.10%),with significant difference(P＜0.05).ConclusionLaparoscopic surgery has obvious curative effect in the treatment of inguinal hernia in adult patients,and the incidence rate of complication and recurrence rate of laparoscopic transabdominal preperitoneal repair are lower.
2017 Vol. 24 (34): 28-30 [Abstract] ( 201 ) HTML (35 KB)  PDF  (0 KB)  ( 43 )
31 Application effect of modified disposable gastric tube in patients with acute oral poisoning
QIU Shi-zhen
ObjectiveTo analyze the application effect of modified disposable gastric tube in patients with acute oral poisoning.MethodsFrom July 2014 to June 2017,74 acute oral poisoning patients admitted to our hospital were selected and evenly divided into the experimental group(blue balls)andb the control group(red balls)by randomly grasping balls.In the control group,conventional gastric tube was used for intubation,while in the experimental group,modified disposable gastric tube was adopted.The success rate of one-time intubation was compared between the two groups.The clinical efficacy by observing relevant indicators was also compared.ResultsThe success rate of one-time intubation was 97.30%in the experimental group,which was higher than that in the control group accounting for 81.08%,the difference was statistically significant(P＜0.05).The time of gastric lavage in the experimental group was shorter than that in control group,the difference was statistically significant(P＜0.05).The time of atropinization and normal recovery of cholinesterase in the experimental group were earlier than those in the control group,the difference was statistically significant(P＜0.05).The incidence of complications(5.41%)in the experimental group was lower than that in control group(21.62%),the difference was statistically significant(P＜0.05).ConclusionThe application of modified disposable gastric tube in the clinical treatment of acute oral poisoning patients can improve the rescue efficiency and reduce the occurrence of complications during intubation.
2017 Vol. 24 (34): 31-33 [Abstract] ( 189 ) HTML (33 KB)  PDF  (0 KB)  ( 71 )
34 Clinical evaluation of the efficacy of emergency bedside hemoperfusion in acute severe organophosphorus pesticide poisoning
SHI Jia-quan； LI Guo-xian ；CHEN Bin ；HUANG Zuo-cai ；JIANG Fu-chang
ObjectiveTo evaluate the clinical efficacy of acute severe organophosphorus pesticide poisoning by emergency bedside hemoperfusion.MethodsA total of 70 patients with acute severe organophosphorus pesticide poisoning from January 2013 to February 2017 were selected as the study subjects,and were randomly divided into the conservative internal medicine group and the hemoperfusion group according to the random number table methods,with 35 patients in each group.The conservative internal medicine group was given routine internal medical methods for treatment,and the hemoperfusion group was further given emergency bedside hemoperfusion rescue on the basis of the conservative internal medicine group.The total treatment effective rate of acute severe organophosphorus pesticide poisoning,the serum cholinesterase levels,atropine dosage,coma time,time of ventilator use after rescue,and the incidence rate of myasthenia gravis in the middle phase were compared between the two groups.ResultsThe total effective rate in the hemoperfusion group(97.14%)was higher than that in the conservative internal medicine group(77.14%),and the difference was statistically significant(P＜0.05).The serum cholinesterase levels([25.13±8.41]U/L)and the dosage of atropine([235.51±52.61]mg)in the hemoperfusion group after rescue were lower than those([15.39±4.13]U/L,[387.35±73.57]mg)in the conservative internal medicine group,the coma time([10.62±1.21]h)and the time of ventilator use([76.51±11.61]h)were better than those([23.61±2.68]h,[157.35±22.57]h)in the conservative internal medicine group,with significant difference(P＜0.05).The incidence rate of myasthenia gravis in the middle phase in hemoperfusion group was 8.57%,which was lower than 22.86%in the conservative internal medicine group,and the difference was statistically significant(P＜0.05).ConclusionThe clinical efficacy of acute severe organophosphorus pesticide poisoning by emergency bedside hemoperfusion rescue is effective,which can improve the clinical symptoms,shorten the time of coma and the time of ventilator use,reduce the dosage of atropine,restore serum cholinesterase levels,and reduce the occurrence of negative prognosis,which is worthy of promotion.
2017 Vol. 24 (34): 34-36 [Abstract] ( 190 ) HTML (34 KB)  PDF  (0 KB)  ( 56 )
37 Clinical effect of bedside hemofiltration in the treatment of acute heart failure complicated with acute renal failure
LIU Jun-hui；WANG Xue-li
ObjectiveTo investigate the clinical effect of bedside hemofiltration in the treatment of acute heart failure complicated with acute renal failure.Methods68 patients with acute heart failure complicated with acute renal failure who were admitted to the department of cardiology in our hospital from January 2015 to January 2017 were selected as the study subjects.According to the random number table method,the patients were divided into the observation group and the control group,with 34 patients in each group.The control group was given routine treatment,and the observation group was given emergency bedside hemofiltration therapy.Heart rate(HR),respiratory rate(RR),mean arterial pressure(MAP),arterial oxygen pressure(PaO2),serum creatinine(Scr),blood urea nitrogen(BUN),potassium ion(K+),bicarbonate ion (HCO3-)concentration changes after the treatment,as well as the incidence rate of complications during treatment,mortality rate and improvement of cardiac function were compared between the two groups.ResultsCompared with the control group,the level of MAP,HR,RR and PaO2in the observation group were all improved,the difference was statistically significant(P＜0.05).The concentration of BUN,Scr and K+in the observation group was significantly lower than that in the control group,and the concentration of HCO3-was increased,with significant difference (P＜0.05).The incidence rate of complications and the mortality rate were lower in the observation group than that in the control group,with significant difference (P＜0.05).ConclusionBedside hemofiltration is effective in acute heart failure complicated with acute renal failure,which is worthy of clinical popularization.
2017 Vol. 24 (34): 37-39 [Abstract] ( 187 ) HTML (36 KB)  PDF  (0 KB)  ( 47 )
40 Effect of Levosimendan associated with blood purification in the treatment of refractory heart failure
XIAO Shi-hui ；LIU Qing-hong
ObjectiveTo explore the effect of Levosimendan associated with blood purification in the treatment of refractory heart failure.Methods80 patients with refractory heart failure who were treated in EICU of our hospital from July 2015 to February 2017 were selected and divided into the control group and the treatment group according to the method of odd and even random grouping,40 cases in each group.The control group was given Dobutamine Torasemide and (or)Furosemide on the basis of conventional heart failure drugs.The treatment group was treated with Levosimendan and blood purification on the basis of routine drugs treatment for heart failure.The level of leftventricular ejection fraction(LVEF),cardiac output index (CI)and NT-proBNP were compared before and after treatment between the two groups.ResultsThe total effective rate after treatment in the treatment group was significantly higher than that in the control group,with significant difference (P＜0.05),the level of LVEF and CI after treatment in the treatment group was significantly higher than that in the control group,the level of NT-proBNP after treatment in the treatment group was lower than that in the control group,with significant difference(P＜0.05).ConclusionThe effect of Levosimendan associated with blood purification in the treatment of refractory heart failure is significant,which is worth applying in clinical.
2017 Vol. 24 (34): 40-42 [Abstract] ( 175 ) HTML (35 KB)  PDF  (0 KB)  ( 76 )
43 Clinical application analysis of intra-aortic balloon counterpulsation in the treatment of acute coronary syndrome
DENG Shi-lei ；PENG Zhi-bin ；YANG Ze-min ；LI Bo-hua
ObjectiveTo analyze the clinical value of intra-aortic balloon counterpulsation in the treatment of acute coronary syndrome.MethodsA total of 60 patients with acute coronary syndromes were enrolled in our hospital from 2010 to 2016.According to the principle of patient autonomy(taking into account the economic status and physical condition),the patients were divided into the observation group and the control group,30 cases in each group.The observation group was given intra-aortic balloon counterpulsation,the control group was given conventional treatment.The clinical effects of the two groups were compared.ResultsCompared with before treatment,the systolic and diastolic blood pressure of the two groups after treatment were significantly improved,with significant difference (P＜0.05).After treatment,the systolic blood pressure and diastolic blood pressure were significantly increased,compared with the control group,there was statistically significant(P＜0.05).The frequency of angina pectoris,the longest duration and the amount of nitroglycerin after treatment were significantly improved in the two groups,compared with before treatment,there was statistically significant(P＜0.05).After treatment,the frequency of angina pectoris and the longest duration of angina pectoris in the observation group were better than those in the control group after treatment,and the difference was statistically significant(P＜0.05).Compared with before treatment,the cardiac function LVEF and BNP were improved in the two groups after treatment,the difference was statistically significant(P＜0.05),especially in the observation group,the difference was statistically significant(P＜0.05).The incidence of adverse reactions,the average hospitalization,and the mortality rate in the observation group were significantly better than those in the control group,with significant difference (P＜0.05).ConclusionIntra-aortic balloon counterpulsation in the treatment of acute coronary syndrome can effectively improve the cardiac function of patients with acute coronary syndrome,it is worth promoting.
2017 Vol. 24 (34): 43-45 [Abstract] ( 194 ) HTML (32 KB)  PDF  (0 KB)  ( 111 )
46 Comparison of the effects of application of Levamlodipine Besylate and Amlodipine Besylate in the treatment of essential hypertension
ZHAN Xin-liang
ObjectiveTo compare the efficacy of Levamlodipine Besylate and Amlodipine Besylate in the treatment of essential hypertension.MethodsAltogether 100 cases of patients with primary hypertension who were treated in our hospital from February 2014 to December 2016 were selected and divided into the control group and the study group different treatment methods,50 cases in each group.The control group was treated with Amlodipine Besylate,and the study group were treated with Levamlodipine Besylate.The blood pressure,heart rate,FMD,PAV,serum NO,ET-1 levels and adverse reactions were compared between the two groups.ResultsThere was no significant difference in blood pressure and heart rate between the two groups (P＞0.05).The level of FMD and PAV in the study group were significantly higher than those in the control group(P＜0.05).The level of serum NO of the study group was significantly higher than that of the control group(P＜0.05),and the level of ET-1 of the study group was significantly lower than that of the control group(P＜0.05).The incidence of adverse reactions of the study group(14.00%)was significantly lower than that of the control group(32.00%)(P＜0.05).ConclusionThe antihypertensive effect of application of Levamlodipine Besylate and Amlodipine Besylate in the treatment of essential hypertension is similar,but the Levamlodipine Besylate has better curative effect and low incidence of adverse reactions in improving vascular endothelial functions with better safety and effectiveness.
2017 Vol. 24 (34): 46-48 [Abstract] ( 211 ) HTML (34 KB)  PDF  (0 KB)  ( 72 )
49 Study on the influence of interventional therapy on cardiac function in the patients with coronary heart disease complicated with left ventricular dysfunction
LI Nan
ObjectiveTo observe the influence of interventional therapy on the cardiac function in patients with coronary heart disease complicated with left ventricular dysfunction.Methods40 patients with coronary heart disease complicated with left ventricular dysfunction in our hospital from April 20 in 2015 to June 20 in 2017 were selected and randomly divided into the control group and the observation group,20 cases in each group.The control group was given conventional treatment,and the observation group was given interventional therapy.The cardiac function index and cardiac function classification were compared between the two groups.ResultsThe levels of LVDs and LVDd in the observation group were significantly lower than those in the control group,while the levels of FS and LVEF in the observation group were higher than those in the control group,with significant difference(P＜0.05).The cardiac function classification in the observation group was significantly better than that in the control group,with significant difference(P＜0.05).ConclusionInterventional therapy applied in the patients with coronary heart disease complicated with left ventricular dysfunction has an important role in improving cardiac function index,with a high safety,which is worthy of investigation.
2017 Vol. 24 (34): 49-51 [Abstract] ( 175 ) HTML (33 KB)  PDF  (0 KB)  ( 49 )
52 Influence of biofeedback therapy on cognitive function in patients with obsessive compulsive disorder
CHEN Mei-ying；CHEN Shang-kun
ObjectiveTo explore the influence of biofeedback therapy on cognitive function in patients with obsessive compulsive disorder.Methods60 patients with obsessive compulsive disorder treated in our hospital from May 2014 to May 2015 were selected as the research object and they were divided into the control group and observation group according to the random number table method,and there were 30 cases in each group.The control group was given routine treatment,while the observation group was treated with biofeedback therapy on the basis of the control group.The study cycle of the two groups was 12 weeks.After treatment,the cognitive function of the two groups was evaluated.ResultsThere was no statistical difference of the related indexes of memory,attention and executive function inpatients between the two groups before treatment(P＞0.05).There was a statistical difference of above-mentioned indexes before and after treatment within the two groups (P＜0.05).After treatment,the immediate memory score of the observation group was higher than that of the control group,and the score of line connection test A,line connection test B and persistent errors were lower than those of the control group(P＜0.05).The delayed memory,total responses and non-persistent error scores of two groups were not statistically significant(P＞0.05).ConclusionBiofeedback combined with conventional medication in treatment of obsessive compulsive disorder has good clinical effect and can effectively improve the cognitive function of patients,which is worthy of clinical promotion and application.
2017 Vol. 24 (34): 52-54 [Abstract] ( 215 ) HTML (30 KB)  PDF  (0 KB)  ( 101 )
55 Clinical effect of decompression of large temporal bone flap with low temporal bone treating severe craniocerebral injury
HUANG Jia-fu ；XIAO Qing-hua ；YUAN Rui ；CHENG Wei
th severe craniocerebral injury given the operation and treated in our hospital from February 2010 to February 2016 were selected as the study object and they were divided into the observation group(50 cases)and control group(42 cases)according to the different surgical method.The observation group was treated with decompression of large temporal bone flap with low temporal bone,while the control group was treated with the standard decompressive craniectomy.The curative effect between the two groups was compared.ResultsThe intracranial pressure level and incidence of complications in the observation group at postoperative 3 days,5 days and 1 week were lower than those of control group,with statistically significant difference (P＜0.05).The two groups showed no statistically significant difference in GOS score and prognosis grading (P＞0.05).ConclusionDecompression of large temporal bone flap with low temporal bone treating severe craniocerebral injury has a more ideal effect,and the clinical application value is higher.It is worthy of popularization and application.
2017 Vol. 24 (34): 55-57 [Abstract] ( 192 ) HTML (31 KB)  PDF  (0 KB)  ( 44 )
58 Effect comparison of percutaneous nephrolithotomy and ureteroscopic lithotripsy in the treatment of impacted upper ureteral calculi
LAI Qing-quan； ZHUANG Hai-nan ；ZENG Yi-bin
ObjectiveTo compare the effect of percutaneous nephrolithotomy and ureteroscopic lithotripsy in the treatment of impacted upper ureteral calculi.MethodsClinical data of 180 patients with impacted upper ureteral calculi treated in urology department of Quanzhou Southeast Hospital from March 2013 to March 2017 was analyzed.According to different treatment measures,90 cases were treated with percutaneous nephrolithotomy(percutaneous nephrolithotomy group)and 90 cases were treated with ureteroscopic lithotripsy (ureteroscopic lithotripsy group).The operation time,blood loss during operation,hospital stay,hydronephrosis remission rate,residual stone rate,the incidence of hematuria combined with renal colic and ureteral perforation in patients of the two groups were observed.ResultsThe operation time,hospital stay in the ureteroscopic lithotripsy group were shorter than those of percutaneous nephrolithotomy group,blood loss during operation was fewer than that of percutaneous nephrolithotomy group,hydronephrosis remission rate in ureteroscopic lithotripsy group was lower than that in percutaneous nephrolithotomy group,and the difference was statistically significant(P＜0.05).There was no significant difference in residual stone rate,the incidence of hematuria combined with renal colic and ureteral perforation between the two groups (P＞0.05).ConclusionUreteroscopic lithotripsy for the treatment of impacted upper ureteral calculi with shorter operation time,less trauma,but has lower hydronephrosis remission rate than percutaneous nephrolithotomy.So,it should select effective surgical measures according to the clinical characteristics of the patients.
2017 Vol. 24 (34): 58-60 [Abstract] ( 199 ) HTML (31 KB)  PDF  (0 KB)  ( 48 )
61 Effect observation of transurethrue resection of prostate and transurethral plasmakinetic resection of prostate treating benign prostatic hyperplasia
ZHU Sheng-huang；HU Jun-quan；LI Tong ； LIU Fan ；ZHOU Hua
ObjectiveTo study the effect of transurethrue resection of prostate(TURP)and transurethral plasmakinetic resection of prostate(TUPKP)treating benign prostatic hyperplasia(BPH).MethodsClinical data of 78 patients with BPH underwent surgical treatment in urology department of Ganzhou Municipal Hospital from March 2015 to April 2017 were retrospectively analyzed and they were divided into two groups according to the different surgical methods.36 patients in group A were treated by TURP,while 42 patients in group B were treated by TUPKP.The operation time,intraoperative blood loss and postoperative recovery index and so on were compared in patients between the two groups.ResultsThere was no statistical difference of the operation time and the weight of the excised gland between the two groups(P＞0.05)and the intraoperative blood loss of group B was significantly fewer than that of group A(P＜0.01),and the incidence of postoperative complications(7.14%)was higher than that of group A (25.00%)(P＜0.05).the postoperative flushing time,indwelling catheter time and hospitalization time of group B were shorter that those of group A(P＜0.01)and IPSS score and QOL score after 3 months operation were lower than those of group A(P＜0.01).The maximum urinary flow rate of group B was higher than that of group A,and the residual urine volume of group B was fewer than that of group A (P＜0.01).ConclusionIn minimally-invasive surgeries treatment of BPH,TUPKP has the features of less surgical trauma and fast postoperative recovery,and is conducive to the recovery of urethral function of patients,which can improve the quality of life in patients and has the popularization value.
2017 Vol. 24 (34): 61-64 [Abstract] ( 193 ) HTML (1 KB)  PDF  (0 KB)  ( 78 )
65 Effect analysis of retroperitoneal laparoscopic ureterolithotomy in the treatment of ureteral calculi
WAN Bin ； ZHANG Wen-sheng； LU Yi-gang
ObjectiveTo observe the effect of retroperitoneal laparoscopic ureterolithotomy in the treatment of ureteral calculi.MethodsFrom January 2012 to December 2016,64 patients suffering from upper ureteral calculi treated in our hospital were selected.According to patients′will for various surgical modes,they were divided into the control group(n=32)and observation group (n=32).The control group was treated with traditional open stone removal operation while the observation group was treated with retroperitoneal laparoscopic ureterolithotomy.The clinical related indexes and occurrence of complications were compared between the two groups.ResultsThe operation time in the observation group was(60.23±1.15)min,and it was shorter than that in the control group([89.22±1.85]min)(t=75.28,P＜0.05).The intraoperative blood loss in the observation group was (30.35±1.54)ml,which was fewer than that in the control group([110.96±1.5]ml)(t=209.38,P＜0.05).The time to be off bed in the observation group was(1.71±0.13)d,which was shorter than that in the control group([3.69±1.02]d)(t=10.89,P＜0.05).The hospital stay of patients in the observation group was(6.13±1.55)d and it was shorter in comparison with that in the control group([8.89±1.74]d)(t=6.70,P＜0.05).The total incidence of complications in the observation group was 3.13%,and it was lower than that in the control group(9.38%)(t=4.27,P＜0.05).ConclusionRetroperitoneal laparoscopic ureterolithotomy treating upper ureteral calculi can obtain a remarkable effect with high safety,which is worthy of promotion.
2017 Vol. 24 (34): 65-67 [Abstract] ( 185 ) HTML (34 KB)  PDF  (0 KB)  ( 39 )
68 Effect of thermal moxibustion combined with Bushen Qianggu Recipe in the treatment of knee osteoarthritis and the effect of inflammatory factors
MEI Ou ；LIU Min
ObjectiveTo analyze the efficacy of thermal moxibustion combined with Bushen Qianggu Recipe in the treatment of knee osteoarthritis(KOA)and the effect of inflammatory factors.MethodsOne hundred patients with KOA in our hospital from May 2016 to May 2017 were observed,all the patients were divided into the combined group and the control group,with 50 cases in each group,by random number table method.The control group was treated with Bushen Qianggu recipe,the combined group was treated with hermal moxibustion and Bushen Qianggu Recipe.Treatment for 3 months,the clinical effects,Lysholm score,VAS score and the levels of inflammatory factors before and after treatment(tumor necrosis factor,interleukin-1,and hypersensitive C-reactive protein)were observed of the two groups.ResultsAfter?treatment for 3 months,the Lysholm score and the total effective rate of the combined group were higher than those of the control group(P＜0.05).The levels of tumor necrosis factor,interleukin-1,hypersensitive C-reactive protein and VAS score in the combined group were significantly lower than those in the control group,the difference was statistically significant(P＜0.05).ConclusionThe combination of thermal moxibustion and Bushen Qianggu recipe can improve the knee function,inhibit inflammatory reaction and relieve the pain of patients in KOA patients,and the clinical efficacy is remarkable.
2017 Vol. 24 (34): 68-70 [Abstract] ( 173 ) HTML (34 KB)  PDF  (0 KB)  ( 97 )
71 Early imaging study on the effect of minimally invasive intervertebral foramen lumbar interbody fusion on lumbar sagittal plane
ZHONG Ming-liang；CHEN Qin；ZHONG Hong-fa；CHEN Yun-sheng；CHEN Rong-chun；LIAO Qi
ObjectiveTo study the early imaging of the effect of minimally invasive transforaminal lumbar interbody fusion(TLIF)on the changes of sagittal parameters of lumbar degeneration(lumbar disc herniation,lumbar spinal stenosis,lumbar spondylolisthesis)and to explore its clinical significance.MethodsThe clinical data of 156 patients with lumbar degenerative disease who were admitted to our hospital from June 2009 to June 2016 were retrospectively collected.All patients were given single-segment minimally invasive TLIF.Parameters such as intervertebral height(DH),lumbar lordosis angle(LL),pelvic incident angle(PI),pelvic tilt angle(PT),sacral tilt angle(SS),L1 plumb line and S1 distance(LASD)and other parameters were observed before surgery,3 days and 3 months after surgery.ResultsLL,LASD and DH were superior to those before operation at 3 days and 3 months after operation in the patients with lumbar disc herniation,and the differences were statistically significant(P＜0.05);LL,LASD and DH were superior to those before operation at 3 days and 3 months after operation in the patients with degenerative lumbar spinal stenosis,and the differences were statistically significant(P＜0.05);LL,PT,SS,LASD and DH were superior to those at 3 days and 3 months after operation in the patients with degenerative lumbar spondylolisthesis,and the differences were statistically significant(P＜0.05).ConclusionEarly minimally invasive TLIF is able to help to improve and maintain the lumbar sagittal sequence.Minimally invasive TLIF has a significance of further clinical promotion.
2017 Vol. 24 (34): 71-73转80 [Abstract] ( 188 ) HTML (35 KB)  PDF  (0 KB)  ( 41 )
74 Clinical effect of percutaneous transforaminal endoscopic discectomy via the interlaminar approach in the treatment of lumbar disc herniation
WU Jun ；LIU Wei ；WANG Mei-lin ；YUAN Xian-yun ；ZHANG Yuan-lin
ObjectiveTo investigate the clinical effect of percutaneous transforaminal endoscopic discectomy(PTED)via the interlaminar approach in the treatment of lumbar disc herniation.Methods56 cases of lumbar intervertebral disc herniation treated in our hospital from March 2015 to March 2017 were selected,and the mathematical random list method was adopted,which was divided into control group and treatment group,with 28 cases in each group.In the control group,removal of nucleus pulposus by PTED,while in the treatment group,on the basis of the traditional surgery,nucleus pulposus was removed by median fenestration or transforaminal lumbar interbody fusion(TLIF).The operation time,total hospital stay,normal time of lumbar function recovery,total effectiveness rate,improvement of pain degree in visual analogue scale (VAS)and Oswestry disability index before and after operation,and the adverse reaction rate in the perioperative period were compared in the two groups.ResultsIn the treatment group,the operation time,total hospital stay,and normal recovery time of lumbar function were shorter than those in the control group(P＜0.05).]Improvement of pain degree(VAS)and Oswestry disability index before and after operation in the treatment group was superior to those in the control group (P＜0.05).The incidence of adverse reaction was 3.6%in perioperative period in the treatment group,which was lower than 21.4%in the control group with statistical significance(P＜0.05).ConclusionFor patients with lumbar disc herniation,on the basis of the traditional operation,implementation of median fenestration or TLIF for the removal of nucleus pulposus can improve the physiological function of the lumbar spine in a short time,maximally control the pain,shorten the therapeutic time,and reduce the adverse reaction,so as to increase the therapeutic effectiveness rate.
2017 Vol. 24 (34): 74-76 [Abstract] ( 196 ) HTML (35 KB)  PDF  (0 KB)  ( 31 )
77 Clinical effect of external fixator and VSD in the treatment of open ankle fracture
ZHOU Chu-kun
ObjectiveTo explore the clinical effect of external fixator and vaccum sealing drainage(VSD)in the treatment of open ankle fracture.Methods86 patients with lumbar disc herniation treated in our hospital From August 2016 to May 2017,according to the random number method,were divided into control group and treatment group,43 cases in each group.The study group adopted the external fixator and VSD;the control group just adopted the external fixator.The healing time of wound surface and bone fracture as well as the incidence rate of complications for two groups were observed.ResultsThe AOFAS index for study group was better than control group,with a statistical difference(P＜0.05);the alignment index for two groups was not significantly different(P＞0.05);the total effective rate for study group(83.72%)was higher than control group 65.12%,with a statistical difference(P＜0.05);the healing time of bone fracture and wound surface for study group was better than control group,with a statistical difference(P＜0.05);the incidence rate of complications for study group(2.33%)was lower than control group 20.93%,with a statistical difference(P＜0.05).ConclusionThe combined method of external fixator and VSD can improve the clinical effect,fix the bone fracture positions,heal the wound cavity,prevent the postoperative complications,stimulate the granulation tissue hyperplasia and promote the healing of wound surface and bone fracture position.It is worthy of clinical promotion and application.
2017 Vol. 24 (34): 77-80 [Abstract] ( 164 ) HTML (39 KB)  PDF  (0 KB)  ( 78 )
81 The Treatment of Minimally Invasive Percutaneous Osteosynthesis for Middle Humeral Shaft Fracture
WEI Xing-xing；CHEN De-wang；CAI Jin-ping
ObjectiveTo evaluate the effect of minimally invasive percutaneous osteosynthesis (MIPO)treatment for middle humeral shaft fracture and postoperative bone metabolism indicators.Methods82 patients with middle humeral shaft fracture who admitted in the department of orthopedics in our hospital from April 2015 to February 2017,The random number grouping method was divided into control group(40 cases)and observation group(42 cases),the control group was treated with traditional open reduction and internal fixation,and the observation group was treated with percutaneous minimally invasive bone plate.The clinical efficacy and bone metabolism indicators after 6 months two groups were compared.ResultsAfter 6 months of treatment,BGP,PICP and PTH level of bone metabolism in the observation group were higher than those in the control group,CTX was lower,and the difference was statistically significant(P＜0.05);Constant-Murley function score and Mayo score in the observation group were higher than those in the control group,and the pain score (VAS pain score)was lower.The difference was statistically significant(P＜0.05).ConclusionThe treatment of minimally invasive percutaneous osteosynthesis for middle humeral shaft fracture is effective,which can better improve limb function and recovery.This treatment is worth promoting.
2017 Vol. 24 (34): 81-83 [Abstract] ( 170 ) HTML (31 KB)  PDF  (0 KB)  ( 47 )
84 Clinical effect of elastic stable intramedullary nail as a minimal invasion of comminuted fracture of fibula complicated with tibia fracture
ZENG Fan-yun； HU Xing-hua
ObjectiveTo investigate the clinical effect of elastic stable intramedullary nail(ESIN)as a micro-invasive therapy on treating comminuted fracture of fibula complicated with tibia fracture.MethodsThe clinical data from 65 patients suffering from comminuted fracture of fibula complicated with tibia fracture from January 2013 to January 2016 in our hospital were retrospectively analyzed.According to different therapeutic methods,they were divided into two groups.In control group(n=30),plate internal fixation was used,while in observation group(n=35),ESIN was adopted.The operation and therapeutic outcome were compared between the two groups.ResultsThe operation time and incision length in the observation group were significantly shorter than those of the control group.The intraoperative amount of bleeding in the observation group was less than that of the control group.The surgical cost in the observation group was lower compared with that of the control group.The differences mentioned above were all displayed statistical significance (P＜0.05).During follow up visits after surgery,the excellent and good recovery rate,healing time of bone fracture,and incidence of complications in the observation group were all superior to those in the control group with significant differences(P＜0.05).ConclusionIn the treatment of comminuted fracture of fibula complicated with tibia fracture,ESIN as a minimal invasion can obtain a favorable effect at advantages of small trauma,few complcations,quick revoery,and cost saving.
2017 Vol. 24 (34): 84-86 [Abstract] ( 172 ) HTML (1 KB)  PDF  (0 KB)  ( 49 )
87 Effect observation of arthroscopic reduction and internal fixation for the treatment of tibial plateau fracture complicated with anterior cruciate ligament avulsion
LING Xiao-peng
ObjectiveTo observe the effect of arthroscopic reduction and internal fixation in the treatment of tibial plateau fracture complicated with anterior cruciate ligament avulsion.Methods62 cases of tibial plateau patients with anterior cruciate ligament avulsion fracture in our hospital from June 2014 to August 2016,were selected,and randomly divided into control group and treatment group,31 cases in each group.The control group receivedconventional open reduction and internal fixation,and the treatment group received arthroscopic reduction and internal fixation.The operation condition,postoperative recovery and postoperative knee function of the two groups were observed and compared,and the clinical efficacy of the two groups was compared.ResultsThe operation time of the treatment group was longer than that of control group,and the amount of bleeding,hospitalization time,healing time of fracture of the treatment group were lower than those of the control group,the differences were statistically significant(P＜0.05);Lysholm score,HSS score and Rasmussen score of the treatment group were higher than the control group,the difference was statistically significant(P＜0.05);the excellent rate of the treatment group was significantly higher than the control group(93.55%vs.74.19%),the difference was statistically significant(P＜0.05).ConclusionArthroscopic reduction and internal fixation of tibial plateau fractures combined with anterior cruciate ligament avulsion can effectively reduce the amount of bleeding,the length of stay and the time of fracture healing,and the recovery of knee function is satisfactory.
2017 Vol. 24 (34): 87-89 [Abstract] ( 160 ) HTML (34 KB)  PDF  (0 KB)  ( 72 )
90 Clinical study of medical ozone water lavage and pain point injection combined treatment of knee osteoarthritis
CHEN Xiao-long；ZHONG Xiang-ming；LI Xiao-yang
ObjectiveTo explore the clinical effect of medical ozone water lavage and pain point injection combined treatment of knee osteoarthritis.Methods120 knee osteoarthritis patients from February 2015 to January 2016 of our hospital were selected as study objects and divided into control group and observation group according to different treatment,each group was 60 cases.The control group was treated with sodium hyaluronate injection in the knee joint cavity.The observation group was treated with medical ozone water lavage combined with pain point injection.The pain situation,knee joint condition after treatment for 1,4 and 12 weeks,and clinical efficacy after treatment for 12 months were compared between the two groups.ResultsThe VAS pain scores of the observation group at fourth weeks and 12 weeks were lower than that of the control group (P＜0.05),and the knee joint score of the first,fourth week was better than that of the control group(P＜0.05).The total effective rate of the observation group was 96.67%,which was higher than 73.33%of the control group (P＜0.05).ConclusionMedical ozone water lavage combined with pain point injection treating knee osteoarthritis with the significant clinical effec,which is worth popularizing and using in clinical practice.
2017 Vol. 24 (34): 90-92 [Abstract] ( 161 ) HTML (35 KB)  PDF  (0 KB)  ( 42 )
93 Short-term effect observation of skipping anterior cervical decompression and fusion in the treatment of two-segment noncontiguous cervical spondylotic myelopathy
WAN Jun ；ZHANG Jing-ye； HUANG Bo；LI Jun； HUANG Yi-jun
ObjectiveTo observe the short-term effect of skipping anterior cervical decompression and fusion in the treatment of two-segment noncontiguous cervical spondylotic myelopathy.Methods42 patients suffering from two-segment noncontiguous cervical spondylotic myelopathy skipping anterior cervical decompression and fusion were enrolled,from May 2012 to May 2017 in our hospital.By using the method to random number table is divided into control group and observation group,21 cases in each group,the control group conventional therapeutic method and the observation group skipping anterior cervical decompression and fusion in random.The improvement rate,segmental anterior convex angle,NDI and JOA scores in two groups were compared.ResultsThe indexes of improvement rate,segmental anterior convex angle,NDI and JOA scores in patients of the observation group treated by skipping anterior cervical decompression and fusion were all superior to those in the control group(P＜0.05).ConclusionFor patients with two-segment noncontiguous cervical spondylotic myelopathy,application of skipping anterior cervical decompression and fusion can increase the improvement rate,be beneficial for restore the physiological curvature of the cervical vertebra,and improve the patient's segmental anterior convex angle.
2017 Vol. 24 (34): 93-95 [Abstract] ( 146 ) HTML (33 KB)  PDF  (0 KB)  ( 74 )
96 Study on treatment of persistent ectopic pregnancy after conservative operation of laparoscopic tubal pregnancy
LIAO Can
ObjectiveTo investigate the clinical effect of two different kinds of treatment in the prevention of persistent ectopic pregnancy after conservative operation of laparoscopic fallopian tube pregnancy.MethodsForty patients with tubal pregnancy underwent laparoscopic conservative surgery from June 21,2015 to August 25,2017 were divided into two groups according to different treatment methods,20 cases in each group.The patients in the observation group were injected with MTX of the tubal mesangial MTX during the removal of the tubal pregnancy lesion,while the control group was treated with MTX postoperative muscle injection.The operation time,intraoperative blood loss and the time of postoperative blood β-HCG level reduced to normal and postoperative complications of persistent ectopic pregnancy were compared.ResultsThe operation time of the observation group was higher than that of the control group,the difference was statistically significant(P＜0.05).The time of postoperative blood β-HCG level reduced to normal in the observation group was shorter than that in the control group,the difference was statistically significant(P＜0.05).The intraoperative blood loss was compared between the two groups,and the difference was not statistically significant(P＞0.05).The postoperative complications of persistent ectopic pregnancy in the observation group was lower than that in the control group,the difference was statistically significant(P＜0.05).ConclusionThe effect of MTX injection on tubal mesentery in the treatment of tubal pregnancy is effective,which can effectively remove residual trophoblast cells and promote the return of blood β-HCG level to normal value.It is worthy to be applied and popularized clinically.
2017 Vol. 24 (34): 96-98 [Abstract] ( 161 ) HTML (31 KB)  PDF  (0 KB)  ( 71 )
99 The clinical significance of serum KL-6 level changes in children with viral pneumonia
GUO Cai-yun；ZHANG Jin-feng；WEI Chu-hong；YAO Long-yan；SUN Yan-na

ObjectiveTo investigate the clinical significance of KL-6 and LDH level changes in children with viral pneumonia.Methods82 children with viral pneumonia admitted in our hospital from January 2015 to December 2016 were selected as subjects and divided into two groups according to the characteristics of viral pneumonia and severe pneumonia diagnostic criteria:severe group(35 cases)and mild group(47 cases),and 30 healthy children of similar age and sex were selected as control group.Serum LDH levels were measured by rate method before and after treatment,and the levels of KL-6 were measured by enzyme-linked immunosorbent assay (ELISA).The clinical symptom were scored and the correlation between KL-6 level and clinical symptoms were compared.The children of two groups were treated with Ribavirin and Recombinant Interferon,the disappeared time of their cough,wheezing,rales and fever were recorded and the datas were used to made the correlation analysis.ResultsThe levels of serum KL-6 in the severe group and the mild group were significantly higher than that in the control group before treatment,and severe group was significantly higher than that of the mild group,and the differences were statistically significant(P＜0.05).After treatment,the levels of serum KL-6 in the severe group and the mild group were compared,and the difference was not statistically significant(P＞0.05),but it was significantly higher than that of the control group,the differences were statistically significant(P＜0.05).Before treatment,the serum LDH levels of the severe group and mild group were significantly higher than that of the control group,while the mild group was significantly higher than that of the control group,the differences were statistically significant(P＜0.05).After treatment,the serum LDH levels of severe group and the mild group were compared,and the difference was not statistically significant(P＞0.05),but it was significantly lower than that of the control group,the differences were statistically significant(P＜0.05).The score of clinical symptoms in the severe group was significantly higher than in the mild group,and the disappeared time of cough,wheezing,rales and fever in the severe group were significantly higher than those in the mild group,the differences were statistically significant(P＜0.05).The level of KL-6 was positively correlated with the clinical symptom score,cough,wheezing,rale and fever disappearance time (P＜0.05).ConclusionSerum KL-6 level can be used as an effective index for evaluating the severity and prognosis of viral pneumonia in children,and the level of LDH can also be used to reflect the degree of disease change.
2017 Vol. 24 (34): 99-102 [Abstract] ( 163 ) HTML (42 KB)  PDF  (0 KB)  ( 46 )
103 Clinical effect of hysteroscopic tubal intubation in the treatment of tubal obstruction infertility
LIAO Ling-yun
ObjectiveTo investigate the clinical effect of hysteroscopic tubal intubation in the treatment of tubal obstruction infertility.MethodsSixty patients with tubal obstruction infertility who treated in our hospital June 15,2015 to June 18,2015 were divided into two groups according to the different treatment methods.30 cases of the observation group(treated with hysteroscopic fallopian tube intubation),30 cases of the control group(treated with normal oviduct).The rate of tubal patency,incidence of postoperative complications and postoperative pregnancy rate were compared in the two groups of patients.ResultsThe rate of tubal patency of the patients in the observation group was 90.00%,which was higher than 60.00%in the control group,and the difference was statistically significant(P＜0.05).The incidence of postoperative complications in the observation group was 3.33%,which was lower than 20.00%in the control group,and the difference was statistically significant(P＜0.05).The postoperative pregnancy rate of patients in the observation group was 86.67%,which was significantly higher than 30.00%in the control group,and the difference was statistically significant(P＜0.05).ConclusionHysteroscopic tubal cannulation is effective in the treatment of tubal obstruction infertility,not only can improve the obstruction,but also reduce the incidence of complications and improve the postoperative pregnancy rate,clinical application and promotion.
2017 Vol. 24 (34): 103-105 [Abstract] ( 148 ) HTML (34 KB)  PDF  (0 KB)  ( 74 )
106 Effects compare of drug therapy and dietary therapy in children with iron-deficiency anemia
WU Xue-mei；LIN Shi-guang
ObjectiveTo investigate clinical treatment effect of drug therapy and dietary therapy in children with irondeficiency anemia.MethodsA total of 63 children with iron-deficiency anemia who treated in our hospital from June 2014 to June 2016 were divided into treatment group(n=32)and controlled group(n=31)according to the parents′will.The treatment group was supplemented with iron on the basis of diet intervention,the control group was receivedconventional iron treatment.The etiology of IDA children was analyzed and the clinical manifestations,laboratory test indexes and clinical efficacy of children in the two groups were compared.ResultsIn the 63 children with IDA of this study,the children at the age of＜ 1 year old,1-3 years old and＞3 years old and different gender were compared,the difference were not statistically significant(P＞0.05).In the 63 children with IDA,the rural children accounted for 63.5%,children in the big cities accounted for 36.5%,breast-feeding without supplement on time accounted for 66.7%,artificial feeding and mixed feeding accounted for 15.9%and 17.4%respectively,the children′s home areas and feeding type were compared,the differences were statistically significant(P＜0.05).The clinical indicators of two groups of children(including course＞3 months,pale complexion,appetite decreases,hepatomegaly,splenomegaly)were compared,the differences were not statistically significant(P＞0.05).After treatment,the Hb,MCHC,MCV,MCH and SF in the treatment group were higher than those in the control group,and the differences were statistically significant(P＜0.05).The total clinical effective rate of treatment group(96.9%)was higher than that of control group(67.7%),and the difference was statistically significant(P＜0.05).ConclusionIDA is more prevalent in infants and children living in rural.Infants with breast-feeding without supplement are at higher risk for IDA.The children with small dose of iron combination of food are good therapeutic effect.
2017 Vol. 24 (34): 106-108转112 [Abstract] ( 150 ) HTML (37 KB)  PDF  (0 KB)  ( 48 )
109 Clinical observation of laparoscopic surgery in gynecological surgery
CHEN Su-ping
ObjectiveTo investigate the clinical efficacy and safety of laparoscopic surgery in the treatment of gynecological diseases.Methods158 patients with gynecological surgery admitted in our hospital from December 2015 to February 2017 were selected as the subjects.The patients were divided into two groups according to the random number table method,79 patients in each group.The patients in the study group underwent laparoscopic surgery,while the patients in the control group underwent laparotomy.The operation time,intraoperative blood loss,the postoperative exhaust time and the hospitalization time were compared between the two groups.ResultsAll of the patients in the study group underwent laparoscopic surgery successfully.The operation time was compared between the two groups,and the difference was not statistically significant(P＞0.05).The intraoperative blood loss of the patients in the study group was significantly lower than that in the control group,the postoperative exhaust time and hospitalization time were significantly shorter than those in the control group,and the differences were statistically significant(P＜0.05).ConclusionCompared with laparotomy,laparoscopic gynecological surgery has the advantages of less bleeding,quick recovery after operation,less complication and less risk of trauma in patients with high safety and belongs to the important surgical method of preserving the uterus.
2017 Vol. 24 (34): 109-112 [Abstract] ( 155 ) HTML (37 KB)  PDF  (0 KB)  ( 80 )
113 Effect of family rehabilitation on motor ability in children patients with cerebral palsy
WAN Li-qing ；WANG Jun ；DENG Jun-biao
ObjectiveTo investigate the effect of rehabilitation center and family rehabilitation on the motor ability in children patients with cerebral palsy.MethodsFrom January 2015 to October 2010,100 pediatric patients with cerebral palsy treated in our hospital were selected as research objects.By random number table method,they were evenly divided into observation group and control group,50 cases in each group.In the control group,routine rehabilitation model was used and family rehabilitation mode was adopted in the observation group.The therapeutic effect,gross motor function classification system (GMFCS)in cerebral palsy and therapeutic satisfaction by family members in the two groups were compared.ResultsThe total therapeutic efficiency in the observation group(92.0%)was significantly higher than that in the control group (82.0%),and the difference was statistically significant(P＜0.05).In observation group,proportion of children with GMFCS gradingⅠandⅡwere higher than those in the control group,gradingⅢandⅤin the observation group were significantly lower than those in the control group,the differences were statistically significant(P＜0.05).The therapeutic satisfaction of the family members of children in the observation group(90.0%)was higher than that in the control group(80.0%),and the difference was statistically significant(P＜0.05).ConclusionFamily rehabilitation has a good application effect in the rehabilitation of motor ability in children with cerebral palsy.It can effectively improve the effect of rehabilitation therapy and motor function,and increase the treatment satisfaction by family members,which is worthy of promotion in clinical practice.
2017 Vol. 24 (34): 113-115 [Abstract] ( 150 ) HTML (34 KB)  PDF  (0 KB)  ( 39 )
116 The clinical effect of improved Mammotome minimally invasive surgery on the treatment of breast lumps
CUI Xiao-yang
ObjectiveTo investigate the clinical effect of improved Mammotome minimally invasive surgery on the treatment of breast lumps.Methods474 patients who were treated in our department from September 2012 to July 2014 were selected as the study subjects and randomly divided into two groups,237 cases in each group.The conventional group was treated with traditional Mammotome surgery.The improved Mammotome minimally invasive group was treated with preoperative vascular ultrasound on the basis of conventional surgery.The incidence of complications(postoperative hematoma and bruises,skin damage and pigmentation anddimple replica time＞1 month),the time of postoperative mean bandage removed and the satisfaction of the therapeutic effect were compared between the two groups.ResultsPostoperatively,in the improved Mammotome minimally invasive group,the rate of patients with hematoma and skin bruises(0.42%),skin damage and pigmentation(1.27%),dimple replica time＞1 month incidence(0.84%)were significantly lower than those in the conventional group(8.02%,9.28%,5.49%),and the differences were statistically significant(P＜0.05).The time of postoperative mean bandage removal of patients in the improved Mammotome minimally invasive group was[(1.91±0.80)d],which was significantly shorter than that of the conventional group [(7.93±5.40)d],and the difference was statistically significant(P＜0.05).The satisfaction of patients in the improved Mammotome minimally invasive group was 77.64%,which was significantly higher than that of the conventional group(61.60%),and the difference was statistically significant(P＜0.05).ConclusionThe use of improved Mammotome minimally invasive surgery in the treatment of breast lumps compared with traditional Mammotome surgery can significantly reduce the incidence of postoperative complications in patients with reduced postoperative removal of the bandage and improve patient satisfaction,therefore,it is worthy of clinical application.
2017 Vol. 24 (34): 116-118 [Abstract] ( 147 ) HTML (33 KB)  PDF  (0 KB)  ( 67 )
119 Contraceptive effect of Mirena intrauterine device(IUD)in different time periods after induced abortion
GU Mei
ObjectiveTo investigate the clinical contraceptive effect of Mirena intrauterine device (IUD)in different time periods after induced abortion.Methods58 women who were given induced abortion and were voluntarily placed with Mirena IUD who were admitted to our hospital from April 2014 to April 2016 were selected as the study subjects.According to the different time periods of the placement of Mirena IUD,the patients were divided into the experimental group and the control group,with 29 cases in each group.Among them,the women who were placed with Mirena IUD immediately after induced abortion were selected as the experimental group,and the women who were placed with Mirena IUD 4-7 days after the first menstruation after induced abortion were selected as the control group.The clinical contraceptive effect of Mirena IUD placed at different time periods was compared between the two groups.ResultsIn terms of the re-use rate and the de-ring rate of Mirena IUD were compared between the the experimental group and control group,and the differences were not statistically significant(P>0.05).The incidence rate of menstrual reduction and slight bleeding were compared between the two groups of women,and the differences were not statistically significant(P>0.05).ConclusionFor women who were given induced abortion and were voluntarily placed with Mirena IUD,the effect of directly placing Mirena IUD after the abortion and placing Mirena IUD after the first menstrual cycle is not significantly different.It does not increase the incidence rate of adverse reactions.Women can avoid a second surgery to achieve the contraceptive effect.This is worthy of clinical learning and further popularization and application.
2017 Vol. 24 (34): 119-121 [Abstract] ( 196 ) HTML (33 KB)  PDF  (0 KB)  ( 70 )
122 Effect of different hemostatic methods on ovarian functions after ovarian cystectomy in growing period
CHEN Li-ying ；WANG Yan-ting
ObjectiveTo compare the effect of different hemostatic methods on ovarian functions after laparoscopic ovarian cystectomy,and to investigate the possible mechanism.MethodsAltogether 80 cases of benign ovarian tumor patients who underwent laparoscopic ovarian cystectomy in our hospital from March 2016 to July 2016 were selected as subjects and were randomly divided into control group and experiment group,40 cases in each group.The ovarian wound of control group was intra-operatively treated with bipolar coagulation hemostasis,while the ovarian wound of experiment group was treated with suture hemostasis.The AFC and AMH levels of the two groups were compared before surgery and 1,3,6 months after surgery.ResultsIn the first month after surgery,the AFC and AMH in both groups were lower than before the surgery,and the differences were statistically significant(P＜0.01).These indexes in the experimental group were higher than those in the control group,and the differences were statistically significant(P＜0.05).Three months after surgery,the AFC in two groups was higher than the first month after surgery,but still lower than before the surgery,the differences were statistically significant(P＜0.05).These indexes in the experimental group were higher than those in the control group,and the differences were statistically significant(P＜0.01).Six months after surgery,the AFC and AMH in the experimental group were compared before surgery,and the differences were not statistically significant(P＞0.05).ConclusionApplication of suture hemostasis in laparoscopic ovarian cystectomy can better protect the patients′ovarian functions,which is worthy of clinical promotion.
2017 Vol. 24 (34): 122-124 [Abstract] ( 170 ) HTML (35 KB)  PDF  (0 KB)  ( 48 )
125 Analysis of risk factors of preterm birth and complications in 320 late preterm infants
ZHANG Shu； WANG Hui-qin
ObjectiveTo analyze the risk factors and complications of late preterm infants,and provide clinical evidence for further treatment of late preterm infants.MethodsRetrospective investigation and analysis of the clinical data of 320 late preterm infants from January 2014 to December 2016 in department of neonates in our hospital.At the same time,320 term infants who were hospitalized during the same period were randomly selected as the control.Logistic regression analysis was used to screen for risk factors for late preterm infants and analyzed the incidence of complications.ResultsThe main risk factors for premature premature infants were premature rupture of membranes,preplacental placenta,premature stripping of placenta,late intrauterine development,severe preeclampsia,and late-stage infectious diseases (P＜0.05).The incidence of complications of late preterm infants was higher than that in term infants,and the difference was statistically significant(P＜0.05).ConclusionThere are many factors that lead to the occurrence of advanced preterm labor.These related factors must be further studied and interfered.It is necessary to strengthen prenatal care to minimize its incidence.
2017 Vol. 24 (34): 125-128 [Abstract] ( 179 ) HTML (38 KB)  PDF  (0 KB)  ( 39 )
129 Effect of latent period of premature rupture of membranes on delivery outcome and perinatal outcome of full-term pregnant women
HUANG Xiao-xia
ObjectiveTo investigate the effect of latent period of premature rupture of membranes on delivery outcome and perinatal outcome of full-term pregnant women.MethodsAltogether 336 cases of patients with premature rupture of membranes who treated in our hospital from January 2014 to December 2016 were selected as subjects and were divided into three groups according to the length of incubation period:the incubation period＜12 h group,12-24 h group and＞24 h group respectively,with 112 cases in each group.The delivery outcome indexes were observed and recorded,including cesarean section rate,vaginal delivery rate,postpartum hemorrhage rate.The perinatal outcome indicators included neonatal asphyxia,neonatal respiratory distress,neonatal pneumonia and incidence of perinatal infant death were compared.The effect of different incubation period of premature rupture of membranes on delivery outcome and perinatal outcome of pregnant women was analyzed.ResultsThe vaginal delivery rate of the incubation period＜12 h group was higher than that of 12-24 h group and ＞24 h group,while the cesarean section rate of the incubation period ＞24 h group was higher than that of＜12 h group and 12-24 h group,and the differences were statistically significant(P＜0.05).The incidence rate of postpartum hemorrhage of the incubation period ＞24 h group was higher than that of＜12 h group and 12-24 h group,and the difference was statistically significant(P＜0.05).The incidence of perinatal asphyxia,respiratory distress and pneumonia in the incubation period ＞24 h group was higher than those of＜12 h group and 12-24 h group,and the differences were statistically significant(P＜0.05).Perinatal mortality rates of three groups were compared,and the differences were not statistically significant(P＞0.05).ConclusionThe length of the incubation period of premature rupture has a certain effect on the full-term delivery outcome and perinatal outcomes.Shortening the incubation period of premature rupture of membranes can effectively reduce the cesarean section rate and the incidence of postpartum hemorrhage,but also can effectively reduce perinatal complications and improve the quality of maternal and perinatal life.
2017 Vol. 24 (34): 129-131 [Abstract] ( 177 ) HTML (32 KB)  PDF  (0 KB)  ( 66 )
132 Effect of Budesonide Inhalation on the clinical symptoms,humoral immune function and pulmonary function in children with mycoplasma pneumoniae pneumonia
XIAO Dong-xia ；SUN Ji-na ；ZHANG Zi-cai
ObjectiveTo observe the effect of Budesonide Inhalation on the clinical symptoms,humoral immune function and pulmonary function in children with mycoplasma pneumoniae pneumonia.Methods95 cases of mycoplasma pneumonia treated in our hospital from November 2015 to May 2017 were randomly divided into the control group(n=47)and the study group (n=48),the children of control group were treated with Azithromycin,and the children of study group were treated with Azithromycin combined with Budesonide Inhalation.The therapeutic effect before and after 2 weeks of treatment and the changes of clinical symptoms,pulmonary function and immune function of the two groups were observed and compared.ResultsThe total effective rate of the study group was 93.75%,which was significantly higher than that of 72.34%of the control group,the disappearance time of cough,fever and dry and wet rales of the study group were shorter than those of the control group,the differences were statistical significance(P＜0.05).After treatment,the levels of serum immunoglobulin IgA and IgM in the two groups were significantly lower than before treatment,and IgG was significantly higher than before treatment,the IgA and IgM in the study group were significantly lower than that in the control group,the IgG was significantly higher than that in the control group,the differences were statistical significance(P＜0.05).After treatment,the FVC and FEV1of the two groups were significantly higher than before treatment,and the FVC and FEV1of the study group were significantly higher than that in the control group,the differences were statistical significance(P＜0.05).ConclusionFor the children with mycoplasma pneumoniae,the conventional Azithromycin treatment combined with the Budesonide Inhalation treatment can effectively improve the clinical symptoms,pulmonary function and immune function of children with mycoplasma pneumonia,compared with the conventional treatment,the treatment effect is more significant,and it is worthy of popularization and application.
2017 Vol. 24 (34): 132-134转138 [Abstract] ( 204 ) HTML (36 KB)  PDF  (0 KB)  ( 64 )
135 Observation on the spawning effect of artificial rupture of membranes combined with intravenous drip of Oxytocin
LI Gang
ObjectiveTo investigate the spawning effect of artificial rupture of membranes combined with intravenous drip of Oxytocin in the delivery and spawning methods.MethodsFrom June 2015 to January 2017,200 pregnant women with 41-week pregnancy,non-labor,cervical Bishop score of 5-7 points,appropriate estimated fetal weight and head delivery who treated in our hospital were selected as subjects.They were randomly divided into two groups,100 cases in each group.In the control group,the pregnant women were given intravenous drip of Oxytocin for spawning alone,and the pregnant women in the observation group were given artificial rupture of membranes combined with intravenous drip of Oxytocin for spawning.The labor occurrence rate of 2,4,12 and 24 h,induced labor failure rate,first production time,second production time,neonatal Apgar score,neonatal infection number and postpartum 24 h hemorrhagic volume were compared between the two groups.ResultsThe labor occurrence rate of 2,4,12 and 24 h of pregnant women in the observation group was 38%,82%,94%,82%,which were higher than those in the control group (22%,46%,67%,46%),and the induced labor failure rate of pregnant women in the observation group(3%)was lower than that in the control group(10%),the differences were statistically significant(P＜0.05).The first production time of the pregnant women was significantly shorter than that in the control group,and the difference was statistically significant(P＜0.05).The second production time,neonatal Apgar score,neonatal infection number and postpartum 24 h hemorrhagic volume of the two groups were compared,and the differences were not statistically significant(P＞0.05).The cesarean section rate of pregnant women in the two groups was compared,and the difference was not statistically significant(P＞0.05).ConclusionThe spawning effect of artificial rupture of membranes combined with Oxytocin is better than that of intravenous drip of Oxytocin alone,which can shorten the duration of labor,improve the success rate of planned delivery,while the rate of cesarean section and neonatal infection rate are not increased.
2017 Vol. 24 (34): 135-138 [Abstract] ( 153 ) HTML (37 KB)  PDF  (0 KB)  ( 72 )
139 Comparison of CT and MRI in the diagnosis of intracranial sellar tumors
ZHANG Yuan-gang；DAI Yong-liang；WANG Li；ZHAO Fei；ZHANG Lei
ObjectiveTo investigate the diagnostic significance of computed tomography (CT)and magnetic resonance imaging(MRI)in the diagnosis of intracranial sellar tumors.MethodsFrom February 2015 to February 2017,68 patients with intracranial sellar tumors were selected from our hospital.All patients were provided with CT and MRI plain and enhanced scanning.The imaging features of CT,MRI plain and enhanced scanning were recorded respectively,and the detection and accuracy of the two methods were compared.ResultsThere was no significant difference in the detection of tumor type between CT and MRI (P＞0.05).3 cases of glioma were misdiagnosed as pituitary adenoma,2 cases of craniopharyngioma were misdiagnosed as glioma,and 1 case of germ cell tumor was misdiagnosed as glioma by CT scanning with 7 cases of missed diagnosis.In MRI scanning,1 case of craniopharyngioma was misdiagnosed as germ cell tumor,1 case of germ cell tumor was misdiagnosed as glioma.Only 1 case was missed diagnosis.There was no significant difference in missed diagnosis rate and misdiagnosis rate between CT and MRI(P＞0.05).The detection rate of CT was 89.71%(61/68),there was no significant difference,compared with 98.53%(67/68)of MRI(P＞0.05).But the accuracy of detection by MRI was significantly higher than that by CT(97.06%vs.88.24%)(P＜0.05).ConclusionCT can show the high density and calcification of tumor in target area,and MRI can provide clear image and accurate location in high sensitivity.Both of them have advantages and disadvantages,and the joint application can effectively improve the diagnostic accuracy of intracranial sellar tumor.
2017 Vol. 24 (34): 139-141 [Abstract] ( 133 ) HTML (32 KB)  PDF  (0 KB)  ( 41 )
142 Application of CT in differential diagnosis of hepatocellular carcinoma and hepatic cholangiocarcinoma
ZHONG Zeng-you ；JIANG Fa-liang
ObjectiveTo study and analyze the clinical application value of CT in the differential diagnosis of hepatocellular carcinoma and hepatic cholangiocarcinoma.MethodsFrom April 2013 to June 2017,40 patients with hepatocellular carcinoma(HCC)admitted into our hospital were enrolled as the HCC group,and 40 patients with hepatic cholangiocarcinoma treated in the same period were selected as the hepatic cholangiocarcinoma group.CT scan were applied in both groups,and the clinical outcomes of scanning were observed.ResultsThe delayed enhancement rates of arterial and portal venous phases in the hepatic cholangiocarcinoma group were significantly higher than those of the HCC group,with statistical significance(P＜0.05).The maximum diameter of the lesions in patients with hepatic cholangiocarcinoma was greatly smaller than that in HCC patients(P＜0.05).The imaging manifestations of HBsAg positivity,liver cirrhosis,AFP elevation,complicated gallstone,and lymphatic metastasis in the two groups were displayed statistically significant in the two groups (P＜0.05).ConclusionIn clinic,enhanced CT scanning can accurately show the degree of blood supply and tissue-derived of HCC and hepatic cholangiocarcinoma,which is an effective differential diagnostic method for the patients with primary liver cancer.
2017 Vol. 24 (34): 142-144 [Abstract] ( 145 ) HTML (32 KB)  PDF  (0 KB)  ( 37 )
145 Influence analysis of Loxoprofen Sodium applied in different administration time on postoperative analgesia effect for patients undergoing dental implant restoration
LI Bin
ObjectiveTo explore the influence of Loxoprofen Sodium applied in different administration time on postoperative analgesia effect for patients undergoing dental implant restoration.Methods100 patients with dental implant repair treated in department of stomatology of our hospital from January 2014 to June 2017 were selected for study.According to the computer random number grouping method,100 patients were randomly divided into the control group and the observation group,and each group had 50 cases.All patients were treated with Loxoprofen Sodium analgesia in the treatment of implantation,while the control group receivedLoxoprofen Sodium after 3 hours the operation,and the observation group received Loxoprofen Sodium before 30 minutes operation.The pain score,the success rate of oral repair,anxiety score,comfort score and the total satisfaction rate were compared between the two groups.ResultsThe pain score in the observation group was lower than that of the control group after 3 hours,6 hours and 12 hours operation(P＜0.05).The success rate of oral repair in the observation group was not statistically significant compared with the control group (P＞0.05).The preoperative and postoperative anxiety score in the observation group were lower than those of the control group(P＜0.05).The preoperative and postoperative comfort score were higher than those of the control group(P＜0.05).The total satisfaction rate in the observation group was significantly higher than that of the control group(P＜0.05).ConclusionThe analgesic effect of Loxoprofen Sodium given before 30 min dental implant repair treatment for preemptive analgesia is better than that of postoperative analgesia and can relieve the pain and improve the comfort degree of patients and make patients more satisfied with the oral restoration effect.
2017 Vol. 24 (34): 145-147 [Abstract] ( 163 ) HTML (34 KB)  PDF  (0 KB)  ( 80 )
148 Effect observation of Huangqi Injection combined with Labetalol Hydrochloride,Magnesium Sulfate treating pregnancy induced hypertension syndrome
XU Mei
ObjectiveTo investigate the effect of Huangqi Injection combined with Labetalol Hydrochloride,Magnesium Sulfate treating pregnancy induced hypertension syndrome.Methods100 patients with pregnancy induced hypertension syndrome treated in our hospital from June 2014 to December 2015 were selected,and they were divided into the observation group(57 cases)and control group(43 cases)according to the mantissa of admission date.The control group was given Labetalol Hydrochloride combined with Magnesium Sulfate treatment while the observation group was added Huangqi Injection based on the medication of the control group.The therapeutic effect in the two groups was observed.ResultsThe blood pressure of patients in the two groups was significantly better than that before treatment,and the diastolic blood pressure and systolic blood pressure in the observation group was(85.8±3.7)mmHg and(133.1±8.2)mmHg respectively,while it was(91.7±4.3)mmHg and (151.9±9.3)mmHg respectively in the control group,and the improvement in the observation group was significantly better than that in the control group (P＜0.05).After treatment,NO,SOD,24 h urine protein level was(950.7±91.4)mmol/L,(118.2±18.5)U/ml,(1.2±0.1)g respectively,and it was(729.6±85.3)mmol/L,(88.9±15.1)U/ml,(2.0±0.3)g respectively,and the above-mentioned indexes in the observation group was significantly better than the control group,the indicators tended to be normal,and there was a statistical difference between groups(P＜0.05).The cesarean section rate,the incidence of neonatal asphyxia and the incidence of abnormal fetal heart rate in the observation group was 17.5%,7.0%and 7.0%,which were significantly lower than those in the control group(37.2%,16.3%,23.3%) (P＜0.05).ConclusionHuangqi Injection combined with Labetalol Hydrochloride,Magnesium Sulfate treating pregnancy induced hypertension syndrome,three kinds of drugs has synergistic antihypertensive effect,and its effect is significant,maternal and neonatal outcome is good.
2017 Vol. 24 (34): 148-150转159 [Abstract] ( 193 ) HTML (36 KB)  PDF  (0 KB)  ( 69 )
151 Clinical study of nourishing yin,tonifying kidney,and removing blood stasis therapy combined with traditional Chinese herbal fumigation in the treatment of hypertension-induced renal injury
LI Qing-zhen ；SONG Wei-guo

ObjectiveTo observe the effect of oral administration of traditional Chinese medicine combined with external application of traditional Chinese herbal fumigation treating hypertensive nephropathy.Methods78 patients with definite diagnosis of hypertension-induced renal injury were divided into the treatment group (n=42)and control group(n=36)according to the different therapeutic method.In the control group,no other treatment except antihypertension was used,while the treatment group was given antihypertension,oral administration of nourishing yin,tonifying kidney,and removing blood stasis drugs,and traditional Chinese herbal fumigation.The therapeutic effect was compared between the two groups.ResultsAfter treatment,score of symptoms in traditional Chinese medicine were both improved in the two groups,and the treatment group was better than of the control group (P＜0.05).Urinary microprotein and NAG enzyme,and serum cystatin C(Cys-C)were all decreased,and the treatment group was better than of the control group(P＜0.05).The level of serum C-reactive protein (CRP)and endothelin (ET)were both decreased after therapies compared with those before treatment,and there was a statistical difference of the above-mentioned indexes after treatment between the two groups(P＜0.05).ConclusionNourishing yin,tonifying kidney,and removing blood stasis therapy combined with traditional Chinese herbal fumigation can improve TCM symptoms in patients with hypertension-induced renal injury,decrease urine protein and better renal injury.Its mechanism may be associated with ET improvement and inflammatory reaction reduction.
2017 Vol. 24 (34): 151-153 [Abstract] ( 152 ) HTML (37 KB)  PDF  (0 KB)  ( 41 )
154 Impact study of acupuncturing Renying Acupoint on blood flow velocity of bilateral internal carotid artery
CAO Jun-yong；WEI Li-li
ObjectiveTo investigate the influence of acupuncturing Renying Acupoint on blood flow velocity of bilateral internal carotid artery.MethodsFrom June 2015 to April 2017,90 patients with CSA treated in outpatient of our department were selected.According to a single-blind random method,they were divided into the observation group(n=30),control group A (n=30),and control group B (n=30).In the observation group,acupuncture combined with moxibustion were used,while in the control group A,warming-needle moxibustion was applied,and in the control group B,only acupuncture was adopted.The total effective rate,the average blood flow velocity(Vm)and systolic blood velocity(Vs)of the vertebral artery(VA)and basilar artery(BA),and clinical therapeutic effectiveness rate were comparatively analyzed.ResultsThe total effective rate of the observation group was significantly higher than that of the control group A and B(P＜0.05).After treatment,the improvement of Vm and Vs in the observation group was better than that of the control group A and B (P＜0.05).ConclusionThe application of acupuncturing Renying Acupoint treating CSA can effectively improve the Vm and Vs as well as the clinical effect,so it can be applied and promoted in clinical practice.
2017 Vol. 24 (34): 154-156 [Abstract] ( 178 ) HTML (32 KB)  PDF  (0 KB)  ( 37 )
157 The clinical effect analsis of Qingre Liangxue Angong Decoction treating postpartum lochiorrhea of type blood-heat
ZHOU Xiao； LI Yao
ObjectiveTo explore the clinical effect of Qingre Liangxue Angong Decoction treating postpartum lochiorrhea of type blood-heat.MethodsClinical data of 60 patients with postpartum lochiorrhea treated in our hospital from February 2014 to March 2016 was analyzed and they were grouped according to the treatment measure:the control group (Yimucao and Cephalosporin treatment group,n=30)and detection group (Qingre Liangxue Angong Decoction treatment group,n=30).The end time of lochia,the three diameter of uterus and clinical effect in patients of the two groups were observed.ResultsThe end time of lochia[(4.8±0.8)d]in patients of the observation group was shorter than that of the control group[(8.1±1.6)d],the three diameter of uterus[(167.8±50.8)cm3]was smaller than that of the control group[(213.8±62.5)cm3](P＜0.05).The total effective rate of the observation group was 100%,which was higher than that of the control group(80%),and the difference was statistically significant(P＜0.05).ConclusionThe clinical effect of Qingre Liangxue Angong Decoction treating postpartum lochiorrhea of type blood-heat is obvious,and can shorten the end time of lochia,reduce the three diameter of uterus.It is worthy of clinical promotion and application.
2017 Vol. 24 (34): 157-159 [Abstract] ( 171 ) HTML (31 KB)  PDF  (0 KB)  ( 43 )
160 Study on the application of open nursing care for umbilical end of newborn
HU Jian-mei ；LIU Fen； HU Yi
ObjectiveTo analyze the clinical effect of open nursing care for neonatal umbilical cord fracture end.Methods From July 2015 to August 2016,86 newborns in our hospital were selected as the subjects of this study.They were divided into the observation group and the control group according to the random number table,43 newborns in each group.The two groups of newborns were given the same ligation,disinfection methods and broken umbilical methods，and the control group receivedroutine nursing intervention on the basis of this.The observation group received open nursing intervention.The incidence of adverse reactions,nursing satisfaction and shedding time of umbilical cord were compared between the two groups.ResultsThe observation group of neonatal adverse reaction incidence rate was 4.66%,nursing satisfaction was 97.67%,the adverse reactions in the control group the incidence rate was 18.64%,nursing satisfaction was 83.72%,comparison between groups,the differences were statistically significant(P＜0.05).And the observation group neonatal umbilical cord stump shedding time was significantly better than the control group of newborns,the difference was statistically significant(P＜0.05).ConclusionThe use of open nursing intervention can reduce the incidence of adverse events such as inflammation and infection,and improve the satisfaction of the newborn family members.It is worthy of clinical application.
2017 Vol. 24 (34): 160-162 [Abstract] ( 183 ) HTML (34 KB)  PDF  (0 KB)  ( 39 )
163 Study on the application of “lean production”theory in the quality and safety management of psychiatric nursing
JIANG Dong-hua； CHEN Na； LIU Yi-feng
ObjectiveTo study the application of “lean production”theory in the nursing safety management of psychiatric department,explore the effective mode of nursing safety management in psychiatric department.Methods25 cases psychiatric nurses in our hospital were selected,from April 2016 to May,the nursing safety management routine was adopted(control group),from June 2016 to November,the “lean production”theory and management tools were applied to psychiatric nursing quality and safety management(observation group).The nursing safety quality,patient satisfaction and nurses′safety knowledge were compared between the two groups.ResultsThe implementation of lean management,the observation group in check system pass score was (96.93±1.13)points,security checks pass score was (97.5±1.25)points,the satisfaction of the patients was (98.95±0.95)%,the nurse safety knowledge rate was 90.83%.Compared with the control group,the results of each examination were significantly higher than those in control group,the differences between the two groups were statistically significant(P＜0.05）.ConclusionThrough the implementation of lean management in the nursing safety system,it can effectively improve the patient satisfaction,improve the safety awareness of nurses,improve the quality of nursing safety,and the concept of“lean production” is safe and effective.
2017 Vol. 24 (34): 163-165转168 [Abstract] ( 173 ) HTML (35 KB)  PDF  (0 KB)  ( 49 )
166 Application effect of nursing intervention in prevention of pulmonary infection after operation of Obstetrics and Gynecology
WANG Li-jing
ObjectiveTo investigate the effect of nursing intervention on prevention of pulmonary infection after gynecological operation.MethodsFrom February 2016 to April 2017,108 cases receivedsurgical treatment in the Department of gynaecology and obstetrics our hospital as the research object,according to the random number expression of 108 patients were randomly divided into study group and control group,54 cases in each group.The study group was given comprehensive nursing intervention,the control group was given routine nursing measures,occurrence the rate of pulmonary infection rate were compared between two groups after operation and satisfaction of nursing quality.ResultsThe incidence rate of the study group was 7.41%,and in the control group,the incidence rate of pulmonary infection was 25.93%.The incidence of pulmonary infection in the study group was significantly lower than the control group,data statistically significant difference(P＜0.05);nursing satisfaction of patients in the study group(92.59%)was significantly higher than the control group patients nursing satisfaction(72.22%),with statistical significance the difference of data(P＜0.05).ConclusionNursing intervention can effectively prevent the occurrence of pulmonary infection in obstetrics and gynecology operation,and effectively improve the patient′s satisfaction with the nursing service.It is worth clinical reference.
2017 Vol. 24 (34): 166-168 [Abstract] ( 166 ) HTML (30 KB)  PDF  (0 KB)  ( 77 )
169 Effectiveness of application of personalized preoperative nursing visit in patients undergoing gynecological laparoscopic surgery under general anesthesia
LONG Shun-lan
ObjectiveTo explore the effect of application of personalized preoperative nursing visit in patients underwent gynecological laparoscopic surgery under general anesthesia.MethodsAltogether 112 cases of patients under went gynecological laparoscopic surgery who were treated in our hospital from April 2015 to August 2016 were included in the study and divided into two groups(control group and observation group)according to the different nursing methods,with 56 cases in each group.The control group receivedroutine preoperative visit,and the observation group received personalized preoperative nursing visit.The patients′anxiety,compliance of doctor′s advice and satisfaction of treatment before and after nursing intervention were compared and analyzed between the two groups.ResultsThe anxiety score of observation group after nursing visit was significantly lower than that of control group,with statistically significant difference (P＜0.05）.The excellence rate of patients′compliance of doctor′s advice of observation group was 100.00%,higher than that of control group(87.50%）,with statistically significant difference(P＜0.05）,the patients′satisfaction of preoperative nursing of observation group was 98.21%,significantly higher than that of control group(82.14%),with statistically significant difference(P＜0.05）.ConclusionApplication of personalized preoperative nursing visit in patients undergoing gynecological laparoscopic surgery under general anesthesia can effectively relieve patients′preoperative anxiety,fear and other negative emotions,and improve patients′compliance of doctor′s advice and satisfaction of nursing work,which brings more safety.
2017 Vol. 24 (34): 169-171 [Abstract] ( 186 ) HTML (31 KB)  PDF  (0 KB)  ( 58 )
172 Effect of high flux hemodialysis on parathyroid hormone clearance in maintenance hemodialysis patients and nursing experience
ZHANG Yong-wei
ObjectiveTo investigate the effect of high flux hemodialysis on parathyroid hormone clearance in maintenance hemodialysis patients,and discuss nursing experience.MethodsFrom January to December 2016,94 patients with maintenance hemodialysis in our hospital were selected as the research objects.They were divided into the control group and the observation group by the random number table method,47 cases in each group.The control group was treated with routine hemodialysis combined with routine nursing.The observation group was treated with high flux hemodialysis combined with comfortable nursing.The effect of parathyroid hormone removal after hemodialysis in two groups was observed and compared,and the nursing effect was discussed.ResultsAfter treatment,there was no significant difference in serum calcium level and clearance rate between the two groups(P＞0.05),and the clearance rate of blood phosphorus in the observation group was significantly higher than that in the control group(P＜0.05).The parathyroid hormone levels in the control group were higher than those in the observation group,and the clearance rate of parathyroid hormone was lower than that in the observation group (P＜0.05).The satisfaction degree of nursing in the observation group(97.87%)was obviously better than that in the control group(76.6%),the differences were statistically significant(P＜0.05).Conclusion High flux hemodialysis has good clinical effect on parathyroid hormone removal in maintenance hemodialysis patients,and the related nursing measures also have positive effects on the curative effect of patients.It is worthy of clinical application.
2017 Vol. 24 (34): 172-174 [Abstract] ( 156 ) HTML (33 KB)  PDF  (0 KB)  ( 49 )
175 Application study of targeted nursing in patients with chronic gastric ulcer
PENG Qiu-ping
ObjectiveTo investigate the application effect of targeted nursing in patients with chronic gastric ulcer.Methods81 patients with chronic gastric ulcer from January 2015 to April 2016 were selected and were divided into control group(40 cases)and observation group(41 cases)according to random comprehensive sequential method.The control group was treated with general nursing,and the observation group was used targeted nursing on the basis of control group.The nursing effect of two groups were observed.ResultsThe disease recurrence rate and nursing satisfaction of the observation group were respectively 4.9%and 97.6%,obvious better than 30.0%and 72.5%in control group,and the difference was significant(P＜0.05).A large number of reflux problems occurred in the experimental group was 0.0%,and which was 75.0%in control group,and the difference was significant(P＜0.05).ConclusionThe application of targeted nursing in patients with chronic gastric ulcer is prominent and worth popularizing.
2017 Vol. 24 (34): 175-177 [Abstract] ( 145 ) HTML (31 KB)  PDF  (0 KB)  ( 71 )
178 Effect of contraction lip abdominal breathing training on the comfort of patients undergoing endoscopic sinus surgery
ZHANG Bao-qin
ObjectiveTo investigate the effect of contraction lip abdominal breathing training on the comfort of patients undergoing endoscopic sinus surgery.Methods60 patients undergoing endoscopic sinus surgery from March 2015 to March 2017 were selected as subjects and divided into experimental group (30 cases)and control group(30 cases),according to randomized controlled trial.Rutine nursing care was performed before operation in the two groups.The experimental group was given further contraction lip abdominal breathing training.Throat pain,analgesic use,nocturnal sleep sleep situation,drinking water and comfort between the two groups after operation were observed.ResultsThe postoperative throat pain in experimental group was shorter than the in control group,the difference was statistically significant(P＜0.05）.Nocturnal sleep time was longer than that of the control group,the difference was statistically significant(P＜0.05）.Analgesic use and water consumption were significantly reduced than those in control group,the differences were statistically significant(P＜0.05）.The comfort score was higher than the control group,the difference was statistically significant(P＜0.05）.ConclusionPreoperative master contraction lips abdominal breathing and can be effectively used in postoperative can alleviate postoperative throat pain,prolonged nocturnal sleep time,reduce the amount of drinking water,so as to increase the comfort of the patients.
2017 Vol. 24 (34): 178-180 [Abstract] ( 161 ) HTML (34 KB)  PDF  (0 KB)  ( 70 )
181 Influence of nursing intervention on nursing satisfaction of patients after laparoscopic cholecystectomy
XU Xiu-yun
ObjectiveTo explore the influence of nursing intervention on the satisfaction of patients after laparoscopic cholecystectomy.MethodsFrom September 2015 to March 2017,in our hospital underwent laparoscopic cholecystectomy in the treatment of 96 patients,according to admission order single day which were randomly divided into observation group (n=48)and control group (n=48),the control group was given routine nursing care,observation group was given nursing intervention on the basis of control group,nursing satisfaction,patients with complications,anxiety and depression were compared.ResultsDepression and anxiety score comparison of the two groups showed no significant difference before nursing intervention(P＞0.05),after nursing intervention,observation group′s depression score[(38.69±4.32)points]and anxiety score[(39.05±4.18)points]were significantly lower than the control group[(46.25±4.78)and(47.14±4.42)points],the differences were statistically significant(P＜0.05).The satisfaction rate of the observation group[97.92%(47/48)]was significantly higher than the control group[85.42%(41/48)],the difference was statistically significant(P＜0.05).The complication rate of observation group[10.42%(5/48)]was significantly lower than the control group[29.17%(14/48)],the difference was statistically significant(P＜0.05).ConclusionThe implementation of nursing intervention for patients with laparoscopic cholecystectomy can effectively improve the patient′s bad psychological emotion,reduce the incidence of complications,improve postoperative patient satisfaction with nursing.
2017 Vol. 24 (34): 181-183 [Abstract] ( 191 ) HTML (33 KB)  PDF  (0 KB)  ( 72 )
184 Application effect of long-acting antibacterial materials in patients with peripherally inserted central venous catheter
ZHOU Xiao-bin
ObjectiveTo analyze the application of long-acting antibacterial material(JUC)in the care of local infection and skin allergy in patients with peripherally inserted central venous catheter.MethodsFrom June 2015 to June 2017,106 patients who receivedcentral venous catheter in our hospital were seleted and evenly divided into research group and control group by a random number table.In the control group,the puncture point of peripheral insertion of central venous catheter was covered by 3M transparent dressing,while in the research group,before covering 3M transparent dressing,long-acting antibacterial material was sprayed.The local infection and skin allergy after nursing were compared and analyzed in the two groups.ResultsSymptoms of local infection including sustained swelling and distension,abnormal secretion,pain or pressing pain after placement of central venous catheter.In the research group,the total local infection rate was 5.66%in patients with peripheral insertion of central venous catheter,much lower than that in the control group accounting for 26.52%,the difference was statistically significant(P＜0.05).Skin allergy like itching，rash or blister occurred in both groups.The total skin allergy rate was 9.43%，greatly lower than that in the control group(30.19%),the difference was statistically significant(P＜0.05).ConclusionSpraying JUC to the puncture point from peripheral insertion of central venous catheter before covering 3M transparent dressing remarkably decrease the local infection and skin allergy,which enhances patient′s confidence on early recovery,and is worthy of extensive application in clinic.
2017 Vol. 24 (34): 184-185转188 [Abstract] ( 164 ) HTML (29 KB)  PDF  (0 KB)  ( 58 )
186 Application value of early nursing intervention in prevention of stress ulcer bleeding in patients with severe traumatic brain injury
WANG Hui-fang
ObjectiveTo study the value of early nursing intervention in prevention of stress ulcer bleeding in patients with severe traumatic brain injury.MethodsFrom August 2015 to June 2016,128 cases of severe craniocerebral injury in our hospital were studied,the patients were randomly divided into observation group of 68 cases and 60 cases in the control group.The control group was given routine nursing,the observation group was given early nursing intervention,compared two groups of patients with stress ulcer bleeding and nursing satisfaction.ResultsThe incidence rate of stress ulcer bleeding in the observation group patients was 11.76%,the incidence rate in the control group patients was 55.00%,the control group was significantly higher than that in the observation group,the difference was statistically significant(P＜0.05).The patients′nursing satisfaction rate in observation group was 97.05%;the patients′nursing satisfaction rate in the control group was 65.00%,the difference was statistically significant(P＜0.05).ConclusionEarly nursing intervention is effective in the prevention of stress ulcer bleeding in patients with severe traumatic brain injury,and has high nursing satisfaction,and has practical value.
2017 Vol. 24 (34): 186-188 [Abstract] ( 166 ) HTML (30 KB)  PDF  (0 KB)  ( 71 )
189 Effect of high quality nursing intervention on anxiety in patients with hypokalemia in emergency department
XIA Lian-xiang； XIE Ai-rong ；LI Xiao-hong
ObjectiveTo discuss the effect of high quality nursing intervention on anxiety in patients with hypokalemia in emergency department.Methods60 cases with hypokalemia in emergency department from January 2016 to May 2017 were selected as subjects,and were divided into intervention group and the control group,30 cases in each group.The intervention group was given high quality nursing intervention,while the control group receivedroutine nursing care.Anxiety scores and nursing satisfaction were compared between the two groups before and after intervention.Results After intervention,anxiety scores of two groups decreased apparently,which were lower than those of before intervention,and the difference was statistically significant(P＜0.05).Anxiety scores in the intervention group decreased apparently that than in the control group,and the differences were significant(P＜0.05).Very satisfactory proportion of the intervention group was higher than that of the control group,which showed significant difference(P＜0.05).ConclusionHigh quality nursing intervention for patients with hypokalemia in emergency department can relieve anxiety,and improve nursing satisfaction.
2017 Vol. 24 (34): 189-191 [Abstract] ( 178 ) HTML (37 KB)  PDF  (0 KB)  ( 41 )
192 Observation on the application of unprotected midwifery nursing in promoting natural childbirth of primipara
ZHONG Gui-lian
ObjectiveTo explore the application effect of unprotected midwifery care in promoting natural childbirth of primipara.MethodsFrom May 2015 to May 2017,148 cases of primipara with natural childbirth in our hospital were selected as the research object.Using random number table method,they were divided into the study group and the control group,each group of 74 cases of maternal.The control group was given routine perineal protection midwifery,while the study group was given unprotected midwifery care.The episiotomy,laceration,pain,postpartum hemorrhage,complications and neonatal asphyxia were observed and compared between the two groups.ResultsThe episiotomy rate of the study group（27.0%）was significantly lower than that of the control group(75.7%),and the perineal laceration and perineal pain degree were significantly lower than those of the control group,the differences were statistically significant(P＜0.05).The study group of maternal postpartum hemorrhage,urinary retention,perineal edema and other complications were significantly lower than the control group,the differences were statistically significant(P＜0.05).The two groups of neonatal asphyxia rate comparison,the difference was not statistically significant(P＞0.05).ConclusionApplication of no protection in maternal childbirth midwifery care can effectively reduce episiotomy rate,reduce perineal laceration and pain,and can reduce the incidence of postpartum complications,can promote the natural childbirth,it is worthy of further clinical application.
2017 Vol. 24 (34): 192-194 [Abstract] ( 173 ) HTML (31 KB)  PDF  (0 KB)  ( 79 )
195 Analysis the influence of nursing intervention on surgical treatment of diaphyseal fracture of radius and ulna
CHEN Yu-feng
ObjectiveTo analyze the influence of nursing intervention on surgical treatment of diaphyseal fracture of radius and ulna.Methods48 diaphyseal fracture of radius and ulna patients from March 2014 to March 2017 were selected,and were divided into two groups according to random number method,each group was 24 cases.The control group were receivedroutine nursing intervention,while the observation group were received additional comprehensive nursing intervention on the basis of routine nursing.ResultsAfter the intervention，the limb swelling value,pain score,limb function in two groups were compared at different time,and the differences were statistically significant(P＜0.05).The postoperative fracture function and fracture efficacy in the observation group were significantly better than those in the control group,and the differences were statistically significant(P＜0.05).ConclusionIn the treatment of diaphyseal fracture of radius and ulna,the use of comprehensive nursing intervention has good curative effect,which effective to get rid of limb swelling,pain,accelerate healing and limb function recovery.It is worth promotion in clinical treatment.
2017 Vol. 24 (34): 195-197 [Abstract] ( 167 ) HTML (35 KB)  PDF  (0 KB)  ( 63 )
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