布地奈德雾化吸入对肺炎支原体肺炎患儿临床症状、体液免疫功能和肺功能的影响

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Abstract ObjectiveTo observe the effect of Budesonide Inhalation on the clinical symptoms,humoral immune function and pulmonary function in children with mycoplasma pneumoniae pneumonia.Methods95 cases of mycoplasma pneumonia treated in our hospital from November 2015 to May 2017 were randomly divided into the control group(n=47)and the study group (n=48),the children of control group were treated with Azithromycin,and the children of study group were treated with Azithromycin combined with Budesonide Inhalation.The therapeutic effect before and after 2 weeks of treatment and the changes of clinical symptoms,pulmonary function and immune function of the two groups were observed and compared.ResultsThe total effective rate of the study group was 93.75%,which was significantly higher than that of 72.34%of the control group,the disappearance time of cough,fever and dry and wet rales of the study group were shorter than those of the control group,the differences were statistical significance(P＜0.05).After treatment,the levels of serum immunoglobulin IgA and IgM in the two groups were significantly lower than before treatment,and IgG was significantly higher than before treatment,the IgA and IgM in the study group were significantly lower than that in the control group,the IgG was significantly higher than that in the control group,the differences were statistical significance(P＜0.05).After treatment,the FVC and FEV1of the two groups were significantly higher than before treatment,and the FVC and FEV1of the study group were significantly higher than that in the control group,the differences were statistical significance(P＜0.05).ConclusionFor the children with mycoplasma pneumoniae,the conventional Azithromycin treatment combined with the Budesonide Inhalation treatment can effectively improve the clinical symptoms,pulmonary function and immune function of children with mycoplasma pneumonia,compared with the conventional treatment,the treatment effect is more significant,and it is worthy of popularization and application.

Key words： Mycoplasma pneumoniae Children Budesonide Inhalation Pulmonary function Immune function

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	XIAO Dong-xia
	SUN Ji-na
	ZHANG Zi-cai

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XIAO Dong-xia,SUN Ji-na,ZHANG Zi-cai. Effect of Budesonide Inhalation on the clinical symptoms,humoral immune function and pulmonary function in children with mycoplasma pneumoniae pneumonia[J]. 中国当代医药, 2017, 24(34): 132-134转138.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I34/132

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