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2018 Vol. 25, No. 4
Published: 2018-02-08
 
 
4 Clinical effect of 3D slicer software assisted minimally invasive endoscopic neuroendoscopic surgery on treating hypertensive intracerebral hemorrhage
YI Jian-bo;FAN Xue-zheng;HUANG Jin-neng;LI Ya-ping
ObjectiveTo explore the methods and clinical effects of 3D slicer software assisted minimally invasive surgery in the treatment of hypertensive intracerebral hemorrhage.MethodsFrom August 2016 to June 2017,30 hypertensive patients with cerebral hemorrhage in basal ganglia region in our hospital were selected and divided into the endoscopic surgery group and the craniotomy group according to different therapeutic methods,15 cases in each group.The endoscopic surgery group was treated with 3D slicer software for three-dimensional reconstruction of hematoma andsimulation of surgical approach guiding endoscopic removal of hematoma.In the craniotomy group,conventional bone flap craniotomy for hematoma clearance under the microscope was adopted.The hematoma clearance rate,operation time and mRS score of the two groups were compared.ResultsThe hematoma clearance rate in the endoscopic surgery group was(91.5±5.5)%,which was higher than that in the craniotomy group([85.3±6.8]%),with significant difference(P＜0.05).The operation time in the endoscopic surgery group was(1.6±0.6)h,which was shorter than that in the craniotomy group(4.8±1.4)h,with significant difference (P＜0.05).Three months after surgery,the mRS score in the endoscopic surgery group was(3.3±1.4)points,which was lower than that of the craniotomy group([4.3±1.7]points),with significant difference (P＜0.05).ConclusionApplication of 3D slicer software to assist neuroendoscopic minimal-invasion surgery in the treatment of hypertensive intracerebral hemorrhage can improve hematoma clearance rate,shorten operation time by precise surgical approach.The prognosis of patients in the endoscopic surgery is superior to that by craniotomy for hematoma clearance under the microscope.
2018 Vol. 25 (4): 4-7 [Abstract] ( 230 ) HTML (35 KB)  PDF  (0 KB)  ( 131 )
8 Comparison of effect of Aripiprazole,Olanzapine and Risperidone in the treatment of children and adolescents with schizophrenia
DUAN Xia-xia;HE Rui-feng;ZHANG Yan;YANG Jin-yu;LIU Li-na;GUO Xuan
ObjectiveTo compare the efficacy of Aripiprazole,Olanzapine and Risperidone in the treatment of children and adolescents with schizophrenia.Methods86 patients with schizophrenia in the Department of Child and Adolescent Psychology in Xi′an Mental Health Center from September 2015 to July 2017 were selected as the research objects,the patients were randomly divided into the Aripiprazole group(29 cases),the Olanzapine group(29 cases)and the Risperidone group (28 cases),Aripiprazole,Olanzapine and Risperidone were given respectively.The efficacy and safety of each drug were evaluated by positive and negative symptoms scale(PANSS)and the test and error support system(TESS)before treatment and after 6 weeks treatment,and serum prolactin (PRL)levels were detected at the same time.ResultsThe PANSS scores of the three groups were significantly lower after the treatment,and the differences were statistically significant(P＜0.01).There was no significant change in PRL level after treatment in patients in the Aripiprazole group,and the difference was not statistically significant(P＞0.05).The PRL levels of the Olanzapine group and the Risperidone group were significantly higher after treatment,and the differences were statistically significant(P＜0.01).There was no statistically significant difference in rhe TESS score between the three groups (P＞0.05).ConclusionThree drugs show similar efficacy in the treatment of schizophrenia in children and adolescents,but Olanzapine and Risperidone treatment can significantly increase serum PRL levels.
2018 Vol. 25 (4): 8-11 [Abstract] ( 317 ) HTML (33 KB)  PDF  (0 KB)  ( 87 )
12 Value of 64-slice spiral CT angiography in the diagnosis of intracranial aneurysm
LYU Jian-guang;LIANG Li-juan;FU Wei-ping;ZENG Fan-meng;LIANG Ya-ming;ZHANG Li-li;YIN Zhi-bin
ObjectiveTo explore the application value of 64-slice spiral CT in the diagnosis of intracranial aneurysms.Methods30 patients with subarachnoid hemorrhage chosen from May 2016 to March 2017 in our hospital were selected and underwent both CT angiography and DSA respectively.The detection rates of intracranial aneurysms of the CT angiography and DSA were compared.ResultsIn 30 cases of subarachnoid hemorrhage,25 cases were proved intracranial aneurysms by vascular embolization or operation.23 cases of intracranial aneurysms were diagnosed by CT angiography,and the coincidence rate of intracranial aneurysms was 92% (23/25).24 cases of intracranial aneurysms were diagnosed by DSA,the coincidence rate was 96% (24/25).There was no significant difference in the diagnostic rate between the two methods in intracranial aneurysms(P＞0.05).ConclusionCT angiography has high value in the diagnosis of intracranial aneurysms and deserves further promotion in clinical practice.
2018 Vol. 25 (4): 12-15 [Abstract] ( 212 ) HTML (32 KB)  PDF  (0 KB)  ( 67 )
16 Clinical effect of Tirofiban combined with Rosuvastatin in the treatment of different ages patients with unstable angina pectoris
ZHANG Yong-jia ;CHEN De-jun; CHEN Bing-hai;DU Song-geng

 Objective To investigate the clinical effect of Tirofiban combined with Rosuvastatin in the treatment of different ages patients with unstable angina pectoris.Methods 300 patients with unstable angina pectoris treated in our hospital from February 2016 to November 2017 were selected.According to the different age,all patients were divided into the the youth group (20-44 years old),the middle-aged group (45-59 years old)and the elderly group (over 60 years),100 cases in each group.The three groups were treated with Tirofiban combined with Rosuvastatin.The clinical effects,ECG changes,echocardiography and adverse cardiac events in the three groups after treatment were compared.Results The total effective rate in the youth group,the middle-aged group and the elderly group was 93%,91%and 88%respectively,and there was no significant difference (P＞0.05).Electrocardiogram detection results showed that the decline amplitude degree of ST segment in the three groups was significantly lower than that before treatment(P＜0.05).There was no significant difference in the decline amplitude degree of ST segment between the three groups after treatment(P＞0.05).The results of color Doppler echocardiography showed that there was no significant difference in the LVDd and LVST between the three groups after treatment(P＞0.05).There was no significant difference in the attack time and frequency of episodes of angina pectoris after treatment in the three groups(P＞0.05).After treatment,there was no myocardial infarction in the young group.The incidence rate of myocardial infarction in the middle-aged group and the elderly group was 1%and 11%,respectively,there was significant difference between the three groups (P＜0.05).Conclusion Tirofiban combined with Rosuvastatin in the treatment of unstable angina pectoris of different ages has better clinical effect,but the incidence rate of adverse cardiac events in elderly patients is significantly higher than that in young and middle-aged people.
2018 Vol. 25 (4): 16-19转24 [Abstract] ( 214 ) HTML (33 KB)  PDF  (0 KB)  ( 91 )
20 The construction of pH-responsive oral Methotrexate nanoparticles based polyethylenimine
MENG Xiao-li;LONG Ling;CHEN Xiao-yong
ObiectiveTo construct pH-responsive oral Methotrexate(MTX)nanoparticles based polyethylenimine(PEI)for improving the oral bioavailability of Methotrexate.MethodsMTX nanoparticles were prepared by dialysis with MTX and PEI based on multiple non-covalent interactions between them.Physicochemical characteristics of nanoparticles containing morphology,particle size,zeta potential,drug loading,and entrapment efficiency were observed and determined,and in vivo and in vitro drug release profiles were employed to evaluate the pH responsive release ability and the oral bioavailability of MTX/PEI nanoparticles.ResultsThe nanoparticles were successfully prepared as discrete and uniform spheres with positive charges,which exhibited an excellent MTX loading performance,and an obvious pH responsive release behavior that no released in pH=1.2 solvent,but rapidly released in pH=7.4 solvent.Compared with the raw MTX and tablet of MTX,MTX/PEI nanoparticles showed a shorter peak time and higher peak concentration after oral administration,and also a larger area undercurve (AUC).ConclusionOral bioavailability of MTX is significantly improved by MTX/PEI nanoparticle system.Based on this,the MTX/PEI nanoparticlesystem is expected to significantly enhance the oral MTX antitumor activity with a good prospect in application.
2018 Vol. 25 (4): 20-24 [Abstract] ( 189 ) HTML (36 KB)  PDF  (0 KB)  ( 82 )
25 Study development of the pathogenesis of cerebral infarction caused by autoimmune disease
PENG Fei-fei;CHEN Mei-ling
Cerebral infarction is the most common cerebrovascular disease with high fatality rate,high disability rate,and it is easy to recur.Therefore,the screening of high-risk factors of cerebral infarction is of great importance.The most common risk factors for cerebral infarction such as:hyperlipidemia,hypertension,diabetes,TIA,smoking,drinking,heart disease,obesity,history of cerebral infarction,etc.But there are some cerebral infarction patients who do not have the risk factors of cerebral infarction,which indicates that there are other factors that can cause cerebral infarction,such as some cryptogenic factors:congenital patent foramen ovale,autoimmune diseases,inheritance,birth control pills,migraine,etc.This article is a review of the pathogenesis of cerebral infarction caused by autoimmune diseases.
2018 Vol. 25 (4): 25-28 [Abstract] ( 235 ) HTML (33 KB)  PDF  (0 KB)  ( 72 )
29 Research progress of diagnosis and evaluation of pelvic fractures complicated with urethral injury
LIU Qi-lian;ZHU Hua-chen
Although the overall incidence of pelvic fractures complicated with urethral injury is not high,but the condition of pelvic fractures complicated with urethral injury is complicated.Incomplete evaluation and inappropriate treatment will lead to serious postoperative complications,will make it difficult to realize the follow-up treatment,and even lose the opportunity of the follow-up treatment as well as have a serious impact on patients′quality of life.With the development of science and technology,the traditional way to diagnose and evaluate urethral injury is harmful to patients,instead of being beneficial to them.And its limitations also increasingly highlight,in addition,more and more new ways of urethra damage evaluation have also been reported.For the diagnosis,classification and treatment of pelvic fractures complicated with urethral injury,there still exists certain controversies.Integrating with the literature published at home and abroad,this paper discusses the incidence of urethral injury,classification and imaging examination so as to provide certain references for the diagnosis and evaluation of urinary tract injury.
2018 Vol. 25 (4): 29-31转34 [Abstract] ( 173 ) HTML (30 KB)  PDF  (0 KB)  ( 102 )
32 PiCCO monitoring techniques to guide fluid resuscitation and EGDT regimens to direct fluid resuscitation in patients with septic shock
CHEN Jun-feng ;CHEN Jie ;CHEN Hui-ying
ObjectiveTo study the use of PiCCO monitoring techniques to guide fluid resuscitation and EGDT regimes to guide fluid resuscitation in patients with septic shock.Methods90 patients with septic shock treated in our hospital from January 2016 to March 2017 were selected as the subjects,and divided into control group and observation group by random number table method,45 cases in each group.Patients in the control group underwent fluid resuscitation under routine EGDT monitoring,and the patients in the observation group monitored the fluid recovery using the PiCCO technique.The levels of 24 h CVP,MAP,Scv O2,GEDVI,PaO2/FiO2,HR and 24 h after treatment were compared between the two groups.ResultsThe levels of 24 h CVP,MAP,Scv O2,GEDVI,PaO2/FiO2and HR in the observation group were significantly lower than those in the control group,the differences were statistically significant(P＜0.05).The control rate of the observation group(93.33%)was higher than that of the control group(77.78%),the difference was statistically significant(P＜0.05).The mortality of the observation group (2.22%)was significantly lower than that of the control group(6.67%),the difference was statistically significant(P＜0.05).ConclusionPiCCO monitoring technique is more accurate and effective than EGDT regimen in fluid resuscitation in patients with septic shock.It can reflect the changes and distribution of liquid in vivo and improve the success rate of rescue.
2018 Vol. 25 (4): 32-34 [Abstract] ( 218 ) HTML (25 KB)  PDF  (0 KB)  ( 66 )
35 Observation on application of restrictive transfusion in the treatment of acute upper gastrointestinal hemorrhage
CHEN Shao-wu; DENG Shi-rong;QU Chang-chun; GAN Guo-neng
ObjectiveTo investigate the effect of restrictive transfusion in the treatment of acute upper gastrointestinal bleeding.Methods78 patients with acute upper gastrointestinal bleeding treated in our department from January 2014 to October 2016 were selected as the subjects,and divided into control group and observation group,39 cases in each group according to the random principle.In the control group,conventional open positive blood transfusion was used,while in the observation group,restrictive transfusion was adopted.The rate of hemostasis at 24,48 and 72 h,and incidence of adverse reactions after transfusion were compared between the two groups.At the same time,the risk of rebleeding was assessed by Blatchford scoring system.ResultsWithin 24 hours,the rate of hemostasis in the observation group was 28.21%,much higher than that in the control group accounting for 10.26%,and the difference was statistically significant(P＜0.05).The rates of hemostasis at 48 h and 72 h were 48.72%and 84.62%in the observation group,while in the control group,they were 41.03%and 79.49%respectively,without statistical difference (P＞0.05).In comparison of adverse reaction,the total incidence of adverse reactions in the observation group(33.33%)was much lower than that in the control group(53.85%),the difference was statistically significant(P＜0.05).In the Blatchford scoring,the score in the observation group was (2.89±0.75)points,significantly lower than that in the control group for(3.69±0.81)points,the difference was statistically significant(P＜0.05).ConclusionIn patients with acute upper gastrointestinal hemorrhage for transfusion,restrictive mode can be selected.It can not only increase the hemostatic rate but also reduce the risk of rebleeding.Besides,it can also reduce the incidence of adverse reactions during blood transfusion as well as the amount of blood transfusion in clinic,which is worthy of promotion.
2018 Vol. 25 (4): 35-37 [Abstract] ( 232 ) HTML (26 KB)  PDF  (0 KB)  ( 103 )
38 Comparison of the clinical effect between small incision resection and traditional surgery in the treatment of appendicitis
CHEN Hui-qiu ;WEN You-liang
ObjectiveTo observe and explore the clinical effect of small incision resection and traditional surgery in the treatment of appendicitis.MethodsFrom January to December 2016,72 patients with appendicitis treated in our hospital were selected as the study subjects.The patients were randomly divided traditional surgery group and small incision group,with 36 cases in each group.The patients in the traditional surgery group were given traditional surgery,and the patients in the small incision group were given small incision resection.The general situation of surgery,the incidence rate of complications,the recovery rate and the recurrence rate were observed and compared between the two groups.ResultsThe intraoperative blood loss was significantly less in the small incision group than in the traditional surgery group,and the difference was statistically significant(P＜0.05).The length of incision in the small incision group was significantly shorter than that in the traditional surgery group,the difference was statistically significant(P＜0.05).The length of stay in the small incision group was significantly shorter than that in the traditional surgery group,the difference was statistically significant(P＜0.05).The VAS score in the small incision group was significantly lower than that in the traditional surgery group,the difference was statistically significant(P＜0.05).The time of exhaust in the small incision group was significantly shorter than that in the traditional surgery group,the difference was statistically significant(P＜0.05).The cost of hospitalization in the small incision group was significantly lower than that in the traditional surgery group,the difference was statistically significant (P＜0.05).The incidence rate of postoperative complications in the small incision group was significantly lower than that in the control group,the difference was statistically significant(P＜0.05).The postoperative cure rate was 100.00%in the small incision group,which was significantly better than that of 77.78%in traditional surgery group.The recurrence rate was 0.0%in the small incision group,which was significantly lower than that of 22.2%in the traditional surgery,the difference was statistically significant(P＜0.05).ConclusionThe clinical curative effect of small incision resection in the treatment of appendicitis is significantly better than that in the traditional surgery group,which can improve the clinical symptoms,reduce the complications,improve the cure rate,and reduce the recurrence rate.The curative effect is significant,which is worthy of clinical application.
2018 Vol. 25 (4): 38-40 [Abstract] ( 212 ) HTML (24 KB)  PDF  (0 KB)  ( 51 )
41 Analysis of blood pressure changes in elderly patients with hypertension and depression after anti-depressant treatment
HE Zhi-qiu;CHEN Yi
ObjectiveTo investigate the changes of blood pressure in elderly patients with hypertension and depression after antidepressant treatment.MethodsAltogether 168 cases of elderly patients with hypertension and depression who were diagnosed and treated in our hospital from January 2015 to December 2016 were selected as the subjects,and divided into the observation group and the control group according to the random number table method,84 cases in each group.The observation group was given Duloxetine,and the control group was given Duloxetine analog medicine.The course of treatment was 4 weeks.The treatment effect of blood pressure,pre-operational and post-operational Hamilton Anxiety Scale(HAMA),Hamilton Depression Scale(HAMD),diastolic and systolic blood pressure and intra-operational adverse reactions were compared between the two groups.ResultsThe total effective rate of blood pressure treatment of the observation group (95.24%)was higher than that in the control group (85.71%),with statistically significant difference (P＜0.05).There was no statistically significant difference in pre-operational HAMA,HAMD and diastolic blood pressure and systolic blood pressure between the two groups (P＞0.05).The post-operational HAMD,HAMA,diastolic blood pressure and systolic blood pressure of two groups of patients were significantly decreased,and the difference was statistically significant between the two groups(P＜0.05).There was no statistically significant difference in incidence of adverse reactions(P＞0.05).ConclusionAntidepressant treatment can reduce the blood pressure level in elderly patients with hypertension and depression.
2018 Vol. 25 (4): 41-43 [Abstract] ( 208 ) HTML (26 KB)  PDF  (0 KB)  ( 111 )
44 Effect observation on Levofloxacin in the treatment of pulmonary tuberculosis
CHEN Yu
ObjectiveTo investigate the clinical effect of Levofloxacin in the treatment of pulmonary tuberculosis.Methods200 cases of tuberculosis patients treated in our hospital from December 2014 to December 2016 were selected as the study subjects,and randomly divided into observation group and control group by different treatments,100 cases in each group.Patients in the control group were treated with Isoniazid,Rifampicin,Pyrazinamide and Ethambutol.Patients in the observation group were treated with Levofloxacin based on the treatment of control group.The improvement of the symptoms,the cases of sputum negative conversion,absorption of the lung lesions and the adverse reactions of the two groups were compared.ResultsAt 1 month after treatment,the symptom improvement rate in observation group (54%)was significantly higher than that in control group (38%).At 6 months after treatment,the symptom improvement rate in observation group (91%)was significantly higher than that in control group (74%).1 month after treatment,the sputum negative conversion rate in the observation group(91%)was significantly higher than that in the control group(79%).After 6 months,the sputum negative conversion rate in observation group(100%)was significantly higher than that in the control group(85%).The lung absorption rate in the observation group(94%)was higher than that in the control group(73%).The incidence of dverse reactions in the observation group(20%)was significantly lower than the control group(49%),the difference was statistically significant(P＜0.05).ConclusionLevofloxacin in patients with pulmonary tuberculosis can significantly improve clinical efficacy,effectively improve the symptoms of patients,improve sputum negative conversion rate and intrapulmonary lesions absorption rate,reduce the risk of adverse reactions,have a wide range of applications,whicht is worthy of clinical promotion and application.
2018 Vol. 25 (4): 44-46 [Abstract] ( 235 ) HTML (25 KB)  PDF  (0 KB)  ( 102 )
47 Clinical effect of transthoracic minimally invasive transcatheter closure of atrial septal defect guided by body surface echocardiography
CAO Xi-ying LI; Zhang-hong ;LI Shu-lin; LUO Zhi-fang; XIONG Jian-xian
ObjectiveTo investigate the difference of clinical effect of transthoracic minimally-invasive closure and thoracoscopic repair in the treatment of atrial septal defect(ASD)under the guidance of transthoracic echocardiography(TTE)so as to analyze the advantages and disadvantages of two surgeries and discuss the best choice.MethodsNinety patients with ASD who underwent minimally invasive surgery in our hospital from July 2011 to January 2017 were selected and divided into control group and observation group according to the operation mode,with 45 cases in each group.The observation group was treated with transthoracic minimally invasive occlusion guided by body surface TTE,and the control group was treated with video-assisted thoracoscopic repair.The therapeutic effects of the two groups were compared.Altogether There was no significant difference between the two groups(P＞0.05).The operation time,ICU stay time,ventilator use time and hospital stay were significantly shorter in the observation group than those in the control group(P＜0.05).The size of surgical incision in the observation group was significantly smaller than that in the control group (P＜0.05).The total cost of hospitalization in the observation group was lower than that in the control group(P＜0.05).The amount of intraoperative bleeding,postoperative thoracic drainage and total blood transfusion in the observation group were lower than that in the control group (P＜0.05).There was no significant difference in the incidence of postoperative complications between the two groups(P＞0.05).ResultsThere was no significant difference between the two groups(P＞0.05).The operation time,ICU stay time,ventilator use time and hospital stay were significantly shorter in the observation group than those in the control group(P＜0.05).The size of surgical incision in the observation group was significantly smaller than that in the control group (P＜0.05).The total cost of hospitalization in the observation group was lower than that in the control group(P＜0.05).The amount of intraoperative bleeding,postoperative thoracic drainage and total blood transfusion in the observation group were lower than that in the control group (P＜0.05).There was no significant difference in the incidence of postoperative complications between the two groups(P＞0.05).ConclusionBoth the two surgeries are safe and effective methods for the treatment of ASD.But the TTE-guided minimally-invasive ASD closure has the features of less trauma,simple operation and significant clinical effect without extracorporeal circulation,which can be applied in the grass-roots units.
2018 Vol. 25 (4): 47-49转53 [Abstract] ( 207 ) HTML (27 KB)  PDF  (0 KB)  ( 70 )
50 Relationship between heart rate variability and grading of chronic stable angina pectoris and intervention effect by β-blocker
HUANG Zu-jian
ObjectiveTo investigate the relationship between heart rate variability (HRV)and the risk grading of chronic stable angina pectoris(SAP)and the intervention effect by β-blocker.Methods180 patients with chronic stable angina treated in our hospital from May 2015 to May 2017 were selected as the observation group.The observation group was graded according to the severity of angina pectoris of the Canadian cardiovascular society(CCS).At the same time,45 cases of healthy control group in the same period were selected,the time-domain index changes of each group were measured and compared.The observation group was randomly divided into treatment group and control group to analyze the intervention effect of metoprolol on HRV changes in sap patients.ResultsThe severity grade of CCS angina pectoris was significantly lower than that of control group,and HRV decreased linearly with the increase of risk(P＜0.01).After metoprolol intervention,the heart rate variability of sap increased significantly (P＜0.01).The improvement of SDNN,SDANN,sDN nindex,rMSSD and PNN50 in metoprolol group was better than that in control group (P＜0.05).ConclusionThe higher the risk of angina pectoris,the lower the value of HRV.HRV may be a noninvasive method to predict myocardial ischemia and assess the risk.Compared with the control group,the HRV time-domain index of the treatment group improved more significantly than that of the control group.
2018 Vol. 25 (4): 50-53 [Abstract] ( 190 ) HTML (26 KB)  PDF  (0 KB)  ( 74 )
54 Application value of evaluation of nerve conduction velocity in early diagnosis of diabetic peripheral neuropathy
LIU Xiao-yang; YANG Xing-yu
ObjectiveTo evaluate the early diagnosis value of nerve conduction velocity (NCV)for diabetic peripheral neuropathy (DPN).MethodsFrom April,2016 to April,2017,50 patients with DPN extracted from patients treated in our hospital were studied,and they were classified as the observation group,another 50 healthy persons underwent the physical examination in our hospital in the same period were selected as the control group.Then,the nerve conduction velocity were compared between the two groups,and NCV between the symptomatic and asymptomatic group of DPN patients were compared at the same time.ResultsThe exercise NCV and sensory NCV in the observation group were significantly lower than those in the control group(P＜0.05).There was a significant difference in the abnormal rate of MCV and NCV between symptomatic and asymptomatic group (P＜0.05),and there was no significant difference in the abnormal rate of SCV between groups(P＞0.05).In the asymptomatic group,the abnormal rate of SCV was significantly higher than the abnormal rate of MSV (P＜0.05).ConclusionThe early diagnosis of diabetic peripheral neuropathy can be performed by detecting NCV,and NCV can effectively diagnose DPN,and it is of great significance to the prevention and treatment of early disease.
2018 Vol. 25 (4): 54-56 [Abstract] ( 205 ) HTML (25 KB)  PDF  (0 KB)  ( 59 )
57 Effect of arc-shaped incision for expanding skull drilling drainage in the treatment of chronic subdural hematoma
ZHANG Xian-xiang; XIAO Qing-hua ;YIN Jian-yong
ObjectiveTo explore the effect of arc-shaped incision for expanding skull drilling drainage in the treatment of chronic subdural hematoma.MethodsFrom January 2015 to December 2016,32 patients with chronic subdural hematoma admitted into our hospital were selected as the observation group.Another 32 patients with chronic subdural hematoma admitted from January 2013 to December 2014 were treated as the control group.In the control group,percutaneous cone drainage was used,while in the observation group,arc-shaped incision for expanding skull drilling drainage was adopted.The therapeutic effect and incidence of complications were compared between the two groups.ResultsThere was no significant difference in operation time of hospital stay between the two groups(P＞0.05).The total effective rate in the observation group was 93.8%,which was significantly higher than that of the control group(81.3%)(P＜0.05).The total incidence of complications in the observation group was 6.2%,which was greatly lower than that of the control group(25.0%)(P＜0.05).ConclusionArc-shaped incision for expanding skull drilling drainage in the treatment of chronic subdural hematoma can obtain a remarkable effect and is worthy to be promoted.
2018 Vol. 25 (4): 57-59 [Abstract] ( 228 ) HTML (26 KB)  PDF  (0 KB)  ( 97 )
60 Effect of multi-point puncture plus local hypothermia drainage treating the elder severe hypertensive intracerebral hemorrhage
WANG Liang;YUAN Ding; DONG Wei;CHEN Guo;CHEN Zhi-qiang
ObjectiveTo explore the effect of multi-point puncture plus local hypothermia drainage(MPPLHD)treating the elder severe hypertensive intracerebral hemorrhage.MethodsFrom June 2011 to December 2016,81 elder patients with severe hypertensive intracerebral hemorrhage were selected as object and they were divided into MPPLHD group(n=37)and conventional craniotomy group (CC group,n=44)according to the patient situation and family wishes.In CC group,removal of hematoma by standard large bone flap craniotomy was adopted.MPPLHD group was treated with MPPLHD.Hematoma clearance rate,intracranial pressure,brain edema with considerable increment at the third,fifth,seventh day,blood NSE concentration,neurological deficit score(NDS)and activity of daily living(ADL)score were compared between the two groups.ResultsThe first hematoma evacuation rate in MPPLHD group was lower than that in the CC group (P＜0.05）,the hematoma evacuation rate after the third,fifth day operation in MPPLHD group was higher than those in CC group (P＜0.05).Brain edema with considerable increment at the third,fifth,seventh day and blood NSE concentration in MPPLHD group were obviously lower than that of CC group(P＜0.05).After 28 days,3 and 5 months operation,NDS and ADL score in MPPLHD group were better than those of CC group (P＜0.05).ConclusionMPPLHD can effectively remove hematoma and reduce the loss of postoperative nerve function.It is an effective method for the treatment of elder severe hypertensive cerebral hemorrhage.
2018 Vol. 25 (4): 60-63 [Abstract] ( 213 ) HTML (34 KB)  PDF  (0 KB)  ( 40 )
64 Long-term effect exploration of intravenous thrombolytic therapy with recombinant tissue-type plasminogen activator treating acute cerebral infarction
ZHONG Chuan-piao; FANG Ling; LAN Song
ObjectiveTo explore the long-term effect of intravenous thrombolytic therapy with recombinant tissue-type plasminogen activator(r-tPA)treating acute cerebral infarction.MethodsFrom January 2015 to January 2017,100 patients with acute cerebral infarction admitted into our hospital were selected as research objects.Using a random number table method,they were divided into the two groups,and there were 50 cases in each group.All participants were provided with conventional therapy.On the basis of routine treatment,Aspirin Enteric-coated Tablets was added in the control group,while in the observation group,r-tPA was adopted.The clinical effect,prognosis,neurological deficit score,and Barthel index were compared between the two groups.ResultsAfter 3-month treatment,the clinical effect of the observation group was significantly better than that of the control group,and the prognosis in the observation group was better than that in the control group after 3-month treatment(P＜0.05).Before treatment,there was no statistical difference in the score of neurological deficits or Barthel index between the two groups (P＞0.05).After therapy,the score of neurological deficits in the two groups were both lower than those prior treatment(P＜0.05),and Barthel index were significantly higher than those before treatment(P＜0.05).The score of neurological impairment was lower and Barthel index was higher compared with those in the control group (P＜0.05).Conclusionr-tPA intravenous thrombolysis is effective in the treatment of acute cerebral infarction,which can facilitate the recovery of neurological function as well as daily living ability,and helps improve the long-term prognosis of patients.
2018 Vol. 25 (4): 64-66 [Abstract] ( 224 ) HTML (25 KB)  PDF  (0 KB)  ( 89 )
67 Clinical observation of intravenous thrombolysis with Alteplase in the treatment of acute ischemic stroke
ZHAO Shu-tao; GAN Zhi-tao;HUANG Li-shuang;HUANG Yu-qi
ObjectiveTo observe the clinical effect of intravenous thrombolysis with Alteplase in the treatment of acute ischemic stroke.MethodsA total of 92 patients with acute ischemic stroke admitted into our hospital from April 2015 to May 2017 were collected.The patients were divided into the observation group (n=47)and the control group (n=45)according to whether they were thrombolyzed in the thrombolytic time window.Intravenous thrombolysis with Alteplase and routine treatment was given respectively.The curative effect,NIHSS score and incidence rate of adverse events were compared between the two groups.ResultsThe total effective rate of the observation group was 93.6%,which was significantly higher than that of the control group(77.8%)(χ2=4.7533,P=0.0292).The scores of 2 h,24 h,14 d and 3 months of thrombolysis in the observation group were lower than those in the control group(P＜0.05).The total incidence of adverse events in the observation group was 4.3%,which was lower than that of the control group(22.2%)(χ2=6.5429,P＜0.05).ConclusionIntravenous thrombolysis treatment of Alteplase can effectively reduce the degree of neurological deficit in the patients with acute ischemic stroke,reduce the incidence of adverse events and improve prognosis.The clinical effect is significant,which is worthy of reference.
2018 Vol. 25 (4): 67-69 [Abstract] ( 213 ) HTML (24 KB)  PDF  (0 KB)  ( 76 )
70 Clinical effect of early cranioplasty in the treatment of skull defect after traumatic brain injury
YU Hai-guang
ObjectiveTo investigate the clinical effect of early cranioplasty in the treatment of skull defect after traumatic brain injury.MethodsFrom August 2014 to March 2017,90 patients with skull defect after craniocerebral trauma treated in our hospital were selected as the research object,and they were randomly divided into observation group(n=45)and control group(n=45).The control group receivedadvanced cranioplasty,and the observation group received early cranioplasty.The clinical effect,the incidence of complications and satisfaction of the treatment were compared between the two groups.ResultsThe total effective rate of the observation group was 84.44%,which was significantly higher than that of the control group (62.22%),and the difference was statistically significant(P＜0.05).The total incidence of complications in the observation group was 6.67%,which was significantly lower than that of the control group (17.78%),and the difference was statistically significant(P＜0.05).The treatment satisfaction of the observation group was 93.33%,which was significantly higher than that of the control group(66.67%),and the difference was statistically significant(P＜0.05).ConclusionEarly cranioplasty has good clinical efficacy in the treatment of skull defect after traumatic brain injury,and can effectively reduce the incidence of adverse complications,which is suitable for further promotion in the clinical field.
2018 Vol. 25 (4): 70-72 [Abstract] ( 222 ) HTML (25 KB)  PDF  (0 KB)  ( 85 )
73 Comparison of Holmium laser and pneumatic lithotripsy in the treatment of upper-ureteral calculi
YANG Yun-jie ;XU Xun ;LIU Qi;FENG Quan-yao
ObjectiveTo compare the efficacy of Holmium:YAG laser and pneumatic lithotripsy in the treatment of upper-ureteral calculi.MethodsFrom July 2013 to July 2017,506 patients with upper-ureteral calculi were randomly divided into two groups,256 cases in holmium laser lithotripsy group and 250 cases in pneumatic lithotripsy group.The successful rate,stone free rate,complications,operative time and hospital stays were compared between the two groups.ResultsThe effective rate of holmium lithotripsy group was 96.88%,which was higher than 86.40%of the pneumatic lithotripsy group,and the difference was statistically significant(P＜0.05).After 4 weeks of postoperative review,the stone free rate of lithotripsy was 96.88%,and the pressure ballistic lithotripsy was 83.60%,and the difference was statistically significant(P＜0.05).The complication rate of holmium lithotripsy group was 10.16%,lesser than 21.60%of the pressure ballistic-lithotripsy group,and the difference was statistically significant(P＜0.05).There was no significant difference between operation time,hospital stays.ConclusionThe efficiency and safety of holmium laser lithotripsy are superior to pneumatic lithotripsy.Holmium lithotripsy is a safe and effective method for treating ureteral calculi,and worthy of being widely applied in clinic.
2018 Vol. 25 (4): 73-76 [Abstract] ( 192 ) HTML (30 KB)  PDF  (0 KB)  ( 94 )
77 Effect of medium frequency electrical stimulation combined with acupuncture on patients with chronic nonbacterial prostatitis
XIONG Fei
ObjectiveTo investigate the effect of medium frequency electrical stimulation combined with acupuncture on SIg A and VCAM-1 expression in patients with chronic nonbacterial prostatitis.MethodsA total of 500 elderly patients with chronic nonbacterial prostatitis were enrolled in our hospital from August 2013 to April 2017.The patients were divided into study group and control group according to the random number table method,250 cases in each group.The control group was given moderate frequency of chemotherapy,the study group was given intermediate frequency electrotherapy combined with acupuncture treatment.The efficacy,SIg A and VCAM-1 expression levels of the two groups were compared.ResultsThe total effective rate of the study group (98.00%)was significantly higher than that of the control group(82.80%)(P ＜0.05).Before treatment，the levels of prostatic fluid SIg A,prostatic fluid and serum VCAM-1 of the two groups were not statistically significant(P＞0.05).After treatment,the levels of the prostatic fluid SIg A,prostatic fluid serum VCAM-1 of the two groups were reduced,and that of the study group were lower than control group,the differences were statistically significant(P＜0.05).ConclusionMedium frequency electrical stimulation combined with acupuncture has a good effect on the treatment of chronic nonbacterial prostatitis,which adjust the expression of SIg A and VCAM-1 and inhibits the inflammatory response.
2018 Vol. 25 (4): 77-79 [Abstract] ( 219 ) HTML (27 KB)  PDF  (0 KB)  ( 211 )
80 The improvement role of high flux hemodialysis on the toxic and metabolic products and calcium and phosphorus metabolism for uremic patients
GUO Bao-chun;WANG Kang;ZHANG Xin-zhou
ObjectiveTo study the improvement role of high flux hemodialysis(HFHD)on the toxic and metabolic products and calcium and phosphorus metabolism for uremic patients.MethodsThe 80 uremic patients in our hospital during the period from January 2016 to December were randomized into the control group(CHD)and the observation group(HFHD),40 patients in each group.The serum changes of toxic and metabolic product,calcium and phosphorus metabolism on pre-and post-dialysis were detected and compared in two groups.ResultsCompared with the CHD group,the levels of beta2-microglobulin (β2-MG)and soluble transferrin receptor(sTfR)were significantly reduced on post-dialysis in the HFHD group with statistical difference(P＜0.05);compared with the CHD group,the levels of serum phosphorus(P),parathyroid hormone(PTH),alkaline phosphatase(AKP)were obviously decreased on post-dialysis in the HFHD group with statistical difference(P＜0.05).ConclusionThe HFHD can effectively eliminate toxins for uremic patients and improve the abnormal state of calcium and phosphorus metabolism.
2018 Vol. 25 (4): 80-82 [Abstract] ( 208 ) HTML (24 KB)  PDF  (0 KB)  ( 73 )
83 Effect of modified Brisson surgery in the treatment of concealed penis in children
YANG Xiang-li;LIU Lei;LI Ni
ObjectiveTo investigate the clinical efficacy of modified Brisson surgery in the treatment of concealed penis in children.MethodsA total of 92 patients with concealed penis who were admitted to our hospital from January 2015 to July 2016 were selected.In accordance with the order of admission，the patients were divided into groups,46 cases in each group.The routine group was given Devine surgery,and the experimental group was given modified Brisson surgery.The difference was analyzed.ResultsThe score of postoperative penile appearance in the experimental group was higher than that in the routine group，and the elongation length was longer than that in the routine group,the differences were statistically significant(P＜0.05).There was no statistically significant difference in the complication rate between the two groups(P＞0.05).The scores of all dimensions of quality of life in the experimental group were significantly higher than those in the routine group after surgery,and the differences were statistically significant(P＜0.05).ConclusionModified Brisson surgery in the treatment of concealed penis has a significant effect,which is easy to restore normal morphology,and conducive to the normal growth and development,as well as the improvement of quality of life in the children.
2018 Vol. 25 (4): 83-85 [Abstract] ( 201 ) HTML (26 KB)  PDF  (0 KB)  ( 102 )
86 Clinical research on residual pain effect of dorsal spinal radicle block after the plasty of acute lumbar vertebral compression fracture
LI Jin-hai;LIU Yong;ZHONG Qiong
ObjectiveTo explore the clinical effect of dorsal spinal radicle block on alleviating postoperative residual pain in patients undergone the plasty of acute lumbar vertebral compression fracture.MethodsFrom August 2015 to August 2017,92 patients undergone the plasty of acute lumbar vertebral compression fracture were selected as the subjects,and evenly divided into control group and research group in random,46 cases in each group.In the control group,nonsteroidal anti-inflammatory analgesic drugs were used for the intervention of residual pain after operation.In the research group,dorsal spinal radicle block was applied as an intervention.ResultsIn the research group,the improvement of VAS score and Oswestry disability index before and after pain intervention was greater than that in the control group,the difference was statistically significant(P＜0.05).The satisfaction on therapeutic regimen and effect of residual pain control after the plasty of acute lumbar spine compression fracture in the research group(93.5%)was higher in the control group (78.3%),the difference was statistically significant(P＜0.05).The disappearing time of postoperative pain and total hospital stay in the research group were shorter than those in the control group,the difference was statistically significant (P＜0.05).The rate of cases occurred with bad emotions and sleep disorder due to pain after surgery in the research group was lower than that in the control group (P＜0.05).The total effectiveness rate of residual pain control after surgery in the research group(91.3%)was better than that in the control group(71.7%),the difference was statistically significant(P＜0.05).ConclusionFor patients undergone the plasty of acute lumbar vertebral compression fracture,dorsal spinal radicle block as an intervention can effectively alleviate postoperative residual pain,control the symptom in a short time,shorten the therapeutic time after surgery,and prevent the occurrence of bad emotions and sleep disorder,improve the control effect of pain and patient′s satisfaction.
2018 Vol. 25 (4): 86-88转92 [Abstract] ( 183 ) HTML (29 KB)  PDF  (0 KB)  ( 97 )
89 Effect Comparison of arthroscopic double pulley non suture bridge fixation and traditional suture bridge fixation in rotator cuff repair
JIA Feng
ObjectiveTo compare the effect of arthroscopic traditional suture bridge fixation and arthroscopic double pulley non suture bridge fixation in rotator cuff tears repair.Methods75 patients with rotator cuff tears who underwent surgical treatment in our hospital from February 2014 to September 2016 were analyzed retrospectively,and divided into the control group(33 cases)and the study group(42 cases)according to the different treatment.The control group treated with traditional arthroscopic suture bridge fixation,and the study group treated with arthroscopic double pulley suture free bridge fixation.The therapeutic effects of the two groups were compared.ResultsThe shoulder joint Constant score,visual score (VAS),University of California at Los Angeles shoulder score (UCLA),American Shoulder and Elbow Surgeons score (ASES)and the activity of shoulder joint of the two groups at the 1 years after surgery were significantly improved compared with before operation (P＜0.05).The above indicators of the research group compared with the control group showed no significant difference at the 1 years after surgery (P＞0.05).The incidence of ankylosis and rotator cuff tear again of the study group was significantly lower than that of the control group,the difference was statistically significant(P＜0.05).ConclusionCompared with traditional suture bridge fixation,double pulley knotless suture bridge fixation under arthroscopy for the treatment of rotator cuff tear can not obviously improve the patients′postoperative shoulder function scores and shoulder activity degree,but can significantly reduce the risk of the postoperative ankylosis and rotator cuff tear recurrence,and it is simple and easy to operate,with short operation time,which is more widely applicable.
2018 Vol. 25 (4): 89-92 [Abstract] ( 184 ) HTML (28 KB)  PDF  (0 KB)  ( 100 )
93 Clinical effect of reserving spinous process ligament complex in treatment of degenerative lumbar disease
LUO Jie-duo;LUO Yu-qiao;LI Wei-wen;LI Quan-meng;ZHONG Xiao-rong
ObjectiveTo investigate the clinical efficacy of reserving spinous process ligament complex in the treatment of lumbar degenerative diseases.MethodsFrom June 2010 to December 2014,26 cases clinical data of spinous process ligament complex treatment of lumbar degenerative disease was analyzed retrospectively,VAS,JOA and ODI scores were recorded Pre-operatively and at last follow-up.The progress of adjacent segment UCLA classification was analyzed.ResultsAfter follow-uped for 6-36 months,VAS score was imporved from(8.00±0.75)to(1.10±1.05)at the last followup,the difference was statistically significant(P＜0.001);JOA score was improved from (7.45±5.73)points to (23.10±3.05)points at the last follow-up,the difference was statistically significant(P＜0.001).ODI score was imporved from(30.10±10.40)points to(5.10±3.20)points at the last follow-up,the difference was statistically significant(P＜0.001).The clinical results were evaluated by Mac-Nab criteria.The results were excellent in 22 cases,good in 2 cases and fair in 2 cases,with an excellent and good rate of 92.3%.According to UCLA,24 cases without progression,1 case progressed from level B to C,1 case progressed from C to D,there was no need for further surgery.ConclusionReserving spinous process ligament complex in treatment of lumbar degenerative disease can achieve effective decompression,release nerve root compression,promote fusion,and can effectively protect the stability of lumbar spine,reduce adjacent segment degeneration(ASD),the clinical outcomes are satisfied.
2018 Vol. 25 (4): 93-96 [Abstract] ( 180 ) HTML (33 KB)  PDF  (0 KB)  ( 77 )
97 The clinical efficacy of locking plate fixation with deltoid lateral separate approach in the treatment of proximal humeral fractures
GUO Wen-long
ObjectiveTo explore the efficacy of locking plate fixation with deltoid lateral separate approach in the treatment of proximal humeral fractures.Methods65 cases with proximal humerus fracture treated in our hospital from March 2011 to May 2016 were selected as the subjects,and divided into the observation group(32 cases)and control group(33 cases)according to the different operative approaches.The patients in the observation group were treated with locking plate fixation by dehopectoral approach,and the patients in the control group were treated with locking plate fixation by lateral deltoid approach approach.The intraoperative blood loss,operation time,fracture healing time,postoperative complication rate,Constant scores of shoulder function at different times after operation were observed in two groups.ResultsThe intraoperative blood loss of the observation group was(90.2±29.9)ml,and the control group was(240.1±64.9)ml.The fracture healing time of two groups was([79.9±1.7]、[91.0±2.2]d).The difference between the two groups was statistically significant(P＜0.05).There was no significant difference between the observation group([71.9±14.9]min)and the control group ([69.8±15.7]min)in the operation time(P＞0.05).The incidence of postoperative complications in the observation group(6.3%)was lower than that in the control group(15.2%),the difference was statistically significant(P＜0.05).Constant scores in the observation group were better than those in the control group at 3 months after operation,the difference was statistically significant(P＜0.05).ConclusionThe lateral deltoid approach with locking plate fixation has advantages with dehopectoral approach in treatment of proximal humeral fractures,less intraoperative bleeding,shorter fracture healing time,faster recovery of shoulder function and less postoperative complications,which is worth a wide application.
2018 Vol. 25 (4): 97-99 [Abstract] ( 184 ) HTML (26 KB)  PDF  (0 KB)  ( 98 )
100 Observation of the comparison between proximal femoral nail anti-rotation and proximal locking plate in the treatment of gerontism unstable intertrochanteric fracture
SI Rong-fei;LI Yuan-geng
ObjectiveTo compare the effect of proximal femoral nail anti-rotation and proximal locking plate in the treatment of gerontism unstable intertrochanteric fracture.Methods76 cases clinical data of gerontism unstable intertrochanteric fracture patients treated in our hospital from March 2012 to April 2017 were analyzed,and divided into proximal femoral nail anti-rotation group and proximal locking plate group by different fixed mode,38 cases in each group.The operation condition,clinical curative effect,costoperative complications of the two groups were compared.ResultsThe operative incision length,operation time,intraoperative blood loss,intraoperative drainage volume,hospital days,postoperative weight-bearing time,fracture union time of proximal femoral nail anti-rotation group were less than those of proximal locking plate group.The clinical treatment excellent rate(94.3%)of proximal femoral nail anti-rotation group was higher than that of proximal locking plate group(78.9%),the costoperative complications(5.3%)of proximal femoral nail anti-rotation group was lower than that of proximal locking plate group (26.3%),the differences were statistically significant(P＜0.05).ConclusionIn the treatment of the gerontism unstable intertrochanteric fracture patients by proximal femoral nail anti-rotation group,the injury is little,excellent rate is high,costoperative complications is less,and it is worth to be used.
2018 Vol. 25 (4): 100-102 [Abstract] ( 197 ) HTML (25 KB)  PDF  (0 KB)  ( 67 )
103 Evaluation of the effect of lateral percutaneous transforminal endoscopic discectomy in the treatment of lumbar disc herniation
LAI Sheng-wei;LIAO Yu ;XU Sheng; DING Bing-lan
ObjectiveTo investigate the clinical effect of lateral percutaneous transforminal endoscopic discectomy(PTED)in the treatment of lumbar disc herniation(LDH).Methods130 patients with lumbar disc herniation treated in our hospital from March 2015 to March 2017 were selected as the subjects,and randomly divided into two groups,65 cases in each group.The control group received fenestration discectomy (FD)and conventional surgery,while the observation group received underwent PTED.The operation time,postoperative bed rest time,postoperative hospital stay,length of incision,amount of bleeding in the 2 groups were observed.Visual analogue scale(VAS),Oswestry dysfunction index(ODI)and Macnab standard score were measured before and after treatment.ResultsAfter treatment,the total effective rate of observation group was higher than the control group,the difference was statistically significant(P＜0.05).The operation time,postoperative bed time,hospitalization time,blood loss,incision length and other related indicators in the observation group were better than those in the control group,the differences were statistically significant(P＜0.05).After 30 d treatment,the ODI score was compared between the two groups,and the difference was statistically significant(P＜0.05).VAS scores of preoperative,postoperative 3 d and 30 d were compared between the two groups,and the differences were not statistically significant(P＞0.05),the difference of VAS score 24 h postoperative was statistically significant(P＜0.05).ConclusionPTED and FD can effectively treat lumbar disc herniation,but PTED has the advantages of less bleeding,small incision,postoperative bed and hospital stay,less trauma,faster postoperative recovery.The clinical efficacy of PTED is not significantly different from that of FD,and the long-term effect needs further study.So the clinical effect of PTED is good,and it is worth popularizing.
2018 Vol. 25 (4): 103-105 [Abstract] ( 147 ) HTML (30 KB)  PDF  (0 KB)  ( 100 )
106 Efficacy observation of Bacillus licheniformis in the assistant treatment of Helicobacter pylori infection in children
LI Hua-bing; YUE Jun; LI Chen-fang
ObjectiveTo observe the efficacy of Bacillus licheniformis in the assistant treatment of Helicobacter pylori(Hp)infection in children.MethodsFrom March 2014 to March 2016,168 children meeting the diagnostic criteria of Hp infection treated in our hospital were selected as subjects.By random sequence method,they were evenly divided into experimental group A and experimental group B and control group,56 cases in each group.All patients were provided with conventional quadruple therapy for 2 weeks:50 mg/(kg·d)Amoxicillin and Clavulanate Potassium(divide the drug into two times),20 mg/(kg·d)Clarithromycin (divide the drug into two times),0.8 mg/(kg·d)Omeprazole (take in the morning),and 8 mg/(kg·d)Colloidal Bismuth Subsitrate(divided into 3 times,before meals).In the experimental group A,live Bacillus licheniformis was used besides the conventional treatment,0.5 g each time,thrice a day,oral administration after meals.In the experimental group B,on the basis of the conventional treatment,Weisu Granule was added with 5 g each time,3 times per day.The treatment effect of 2 weeks after treatment was compared with that of the three groups,and the change of Hpδ value and the recurrence rate of 2 weeks and 4 weeks after treatment were compared.ResultsAfter 2 weeks of treatment,the symptoms of the three groups were all improved,and the total effective rate of treatment for children in group A and group B was significantly higher than that in the control group,and the differences were statistically significant(P＜0.05).The cure rate of the experimental group A was significantly higher than that of control group and experimental group B,the differences were statistically significant(P＜0.05),while the cure rate of experimental group B was compared with the control group B,the difference was not statistically significant(P＞0.05).After 2 weeks and 4 weeks after treatment,the experimental group A with Hpδ value was lower than the control group and experimental group B,the differences were statistically significant(P＜0.05),the experimental group B with Hpδ value was compared with control group,the difference was not statistically significant(P＞0.05).The recurrence rates of experimental group A was significantly lower than that of the control group and experimental group B,the differences were statistically significant(P＜0.05),the recurrence rate of experimental group B was compared with control group,the difference was not statistically significant(P＞0.05).ConclusionBacillus licheniformis assisted treatment of Hp infection in children obtains a remarkable effect,which can increase the eradication rate and reduce the recurrence rate.It is worthy of application and promotion.
2018 Vol. 25 (4): 106-108 [Abstract] ( 184 ) HTML (29 KB)  PDF  (0 KB)  ( 86 )
109 The clinical value of procalcitonin and C reactive protein in early diagnosis neonatal sepsis
LI Wei-chun ZHANG Ke-changYANG Xu WANG Sheng-dong
ObjectiveTo explore the clinical value of dection procalcitonin(CRP)and C reactive protein(PCT)in early diagnosis neonatal sepsis.Methods113 newborn cases were collected in Chuzhou branch of Nanjing children′s hospital from January 2015 to December 2016 and were selected as the research objects and divided into the sepsis group(91 cases)and non-infected group (22 cases)according to the diagnostic criteria for neonatal septicemia and whether infection was occurred.The levels of PCT and CRP between the sepsis group and non-infected group were compared,the levels of PCT of 32 children in the sepsis group before and after treatment were compared,the sensitivity,specificity,positive predictive value and negative predictive value of PCT and CRP in the diagnosis of neonatal sepsis were analyzed.ResultsThe levels of the PCT and CRP in the sepsis group were higher than those in the non-infected group,and the differences were statistically significant(P＜0.05).The PCT level of 32 children with septicemia after treament was significantly lower than before treatment,and the difference was statistically significant (P＜0.01).The sensitivity of PCT≥2 μg/L to the diagnosis of neonatal sepsis was 74.74%,specificity was 100.00%,the sensitivity of CRP≥8 mg/L to the diagnosis of neonatal sepsis was 54.95%,and the specificity was 81.82%.ConclusionThere are clinical value of detection CRP and PCT in early diagnosis neonatal sepsis and the effect of treatment.Detected PCT combine with CRP were valuable to improve sensitivity and specificity in diagnosis neonatal sepsis.
2018 Vol. 25 (4): 109-111 [Abstract] ( 188 ) HTML (27 KB)  PDF  (0 KB)  ( 103 )
112 Application value of laparoscopic ultrasonography in the myomectomy of intramural myoma of the uterus
GAO Hang; DENG Yan-jie;HOU Jin-ping
ObjectivesTo investigate the application effect of laparoscopic ultrasonography in the myomectomy of intramural myoma of the uterus.MethodsFrom December 2015 to October 2016,80 patients with intramural myoma of the uterus in our hospital were selected as the research objects.According to the different treatment methods,they were divided into the treatment group and the control group,40 cases in each group.The treatment group was treated with laparoscopic ultrasound,and the control groupwas given traditional laparotomy.The amount of intraoperative blood loss,operation time,postoperative hospital stay were compared between the two groups,and the follow-up rate was 3-12 months,the recurrence rate of the two groups was compared.ResultsThe amount of intraoperative blood loss and the cost of hospitalization in the treatment group were significantly less than those in the control group,and the operation time and the time of hospitalization in the treatment group were significantly shorter than those in the control group,with significant difference(P＜0.05).The healing rate of the myometrium in the 3 months after operation and half a year after operation in the treatment group was significantly higher than those in the control group,with significant difference (P＜0.05).There was no significant difference in the healing rate of myometrium between the two groups after 1 years of operation (P＞0.05).After 12 months of follow-up,the recurrence rate of the treatment group was 2.5%,which was lower than 10.0%in the control group,with significant difference(P＜0.05).ConclusionThe effect of laparoscopic ultrasonography is very obvious for the patients with intramural myoma of the uterus,which not only can accurately locate and direct guidance,but also can dig out the lesions of blind spots,and the healing of uterine myometrium is better after operation.It is worthy of popularization and application in clinic.
2018 Vol. 25 (4): 112-115 [Abstract] ( 186 ) HTML (30 KB)  PDF  (0 KB)  ( 68 )
116 Clinical effect of laparoscopic surgery combined with medication in the treatment of ovarian cyst
ZHONG Jian
ObjectiveTo observe and investigate the clinical effect of laparoscopic surgery combined with medication in the treatment of ovarian cysts.MethodsA total of 72 patients with ovarian cyst who were admitted to our hospital from January to December 2015 were selected as the study subjects.The patients were randomly divided into the observation group and the control group by randomized block design,with 36 patients in each group.The observation group was given laparoscopic surgery combined with gestrinone,and the control group was given laparoscopic surgery.The clinical effect,the improvement of clinical symptoms,serum sex hormone levels and the incidence rate of adverse reactions were observed and compared between the two groups.ResultsThe total effective rate of clinical treatment in the observation group was 88.9%,which was significantly higher than 66.7%in the control group,and the difference was statistically significant(P＜0.05).The recurrence rate of patients in the observation group was 11.1%,which was significantly lower than the 33.3%in the control group,and the difference was statistically significant(P＜0.05).The improvement of lumbar sacral dilation,coital pain and dysmenorrhea in the observation group were significantly better than those in the control group,and the differences were statistically significant(P＜0.05).The sex hormone levels of FSH,LH,E2and P of patients in the observation group 1 year postoperatively were significantly lower than before operation,the differences were statistically significant(P＜0.05).The levels of FSH,E2and P of patients in the observation group were lower than those in the control group,while the level of LH was higher than that in the control group,the differences were statistically significant (P＜0.05).There was no significant difference in adverse reactions between the two groups (P＞0.05).ConclusionThe clinical efficacy of laparoscopic surgery combined with Gestrinone in the treatment of ovarian cysts is significant,can effectively improve clinical symptoms,and the adverse reactions is less,which is worthy of clinical promotion and application.
2018 Vol. 25 (4): 116-118 [Abstract] ( 174 ) HTML (27 KB)  PDF  (0 KB)  ( 96 )
119 Application value analysis of modified tubulaxized incised plate urethroplasty in the treatment of hypospadias in children
LI Wei-jun;FU Xiu-mei;ZHONG Bin;LIU Hui
ObjectiveTo investigate the application value of modified tubularized incised plate(TIP)urethroplasty in the treatment of hypospadias in children.MethodsAltogether 82 cases of pediatric hypospadias who accepted surgical treatment in our hospital from March 2014 to March 2016 were selected as subjects and were randomly divided into two groups according to the random number table method,41 cases in each group.The traditional surgical method was used in the control group;while,the observation group were treated with modified TIP urethroplasty.The surgical effectiveness and complications of patients between two groups were compared,the incidence of postoperative urinary fistula was recorded in the observation group.ResultsThe total effective rate of patients in the observation group of postoperative follow-up 6-15 months was 97.56%,which was significantly higher than the 85.37%in the control group,and the difference was statistically significant(P＜0.05),the penis shape of patients were normal with right urethral opening position,smooth urination and no penile curvature.After the operation,the incidence of urinary fistula,urethral stricture and infection in the observation group were significantly lower than those in the control group,and the differences were statistically significant(P＜0.05).Penis scrotal type has the highest incidence of urinary fistula of patients in the observation group,followed by the penis size type,coronary ditch type without urinary fistula.The incidence of urinary fistula in the penis size type,coronary sulcus type and penis scrotal type were compared,and the difference was statistically significant(P＜0.05).The patients with urinary fistula underwent fistulous neoplasty and were recovered,and patients with urinary tract stenosis were treated with urethral dilatation and recovered.ConclusionThe modified TIP urethroplasty has good application value in the treatment of children with hypospadias,can improve the success rate of operation,reduce the risk of postoperative complications and reoperations,and can accelerate the postoperative recovery in children,which has positive clinical significance.
2018 Vol. 25 (4): 119-121转125 [Abstract] ( 169 ) HTML (30 KB)  PDF  (0 KB)  ( 68 )
122 Correlative analysis of maternal leukocyte count,neutrophil count,C-reactive protein and neonatal corresponding index in perinatal pregnant women with high risk factors
WANG Bang;LIU Xiu-xiang;PAN Qi-qi;MA Jin-shuai;ZHANG Huan
ObjectiveTo investigate the relationship between the number of white blood cells (WBC),the neutrophils count,the C reactive protein(CRP)and the corresponding indicators of neonatal births in perinatal pregnant women with high risk factors,and to find early diagnostic indexes for neonatal infection.MethodsThis study was a prospective and cross-sectional study.In this study,170 pregnant women with high risk factors of infection treated in the obstetrics department of the affiliated hospital of Binzhou Medical University from March to August 2017 were selected as subjects.For pregnant women and newborn babies,the blood samples were collected and the WBC number,neutrophil count and CRP were detected by automatic blood routine analyzer.The Pearson or Spearman method were used to analyze the correlation between WBC number,neutrophils,CRP and neonatal corresponding indexes.ResultsThere was no correlation between WBC number,neutrophil count and CRP of 170 pregnant women and corresponding indexes of neonates(P＞0.05).The WBC number and neutrophils count of pregnant women whose gestational age≤34 weeks were correlated with the corresponding indexes of neonates(P＜0.05),while there was no correlation between the CRP of pregnant women whose gestational age≤34 weeks and the CRP of neonates(P＞0.05).There was no correlation between WBC number,neutrophil count and CRP of pregnant women whose gestational age≥34 weeks and the corresponding indexes of neonates (P＞0.05).The WBC number,neutrophil count and CRP of pregnant women whose gestational age ≤34 weeks were consistent with the increase or decrease of the corresponding indexes of neonates.ConclusionThe number of white blood cells and neutrophils in perinatal pregnant women with perinatal pregnancy at gestational age≤34 weeks can be used as an early diagnosis index of neonatal infection.This group of people should be paid attention to.
2018 Vol. 25 (4): 122-125 [Abstract] ( 185 ) HTML (30 KB)  PDF  (0 KB)  ( 95 )
126 Predictive value of transabdominal,transvaginal and perineal ultrasound for preterm delivery
LI Ling-zhi
ObjectiveTo investigate the predictive value of transabdominal,transvaginal and transperineal ultrasound for preterm delivery.MethodsA total of 120 pregnant women with symptoms of threatened preterm birth who were treated in our hospital from December 2015 to March 2017 were selected as subjects and divided into transvaginal ultrasound group,transabdominal ultrasound group and perineal ultrasound group by random number table method,40 cases in each group.The cervical length (CL)of three groups of pregnant women was measured and the relationship between CL and premature delivery was analyzed.ResultsThe CL of 3.0 cm was the boundary,the incidences of preterm birth of pregnant women CL＜3.0 cm of three groups were significantly higher than full-term,and the differences were statistically significant(P＜0.05).The fulfillment ratio of CL determination in the perineal ultrasound group was significantly higher than that in the transvaginal ultrasound group and transabdominal ultrasound group,the fulfillment ratio of CL determination in the transvaginal ultrasound group was significantly higher than that in the transabdominal ultrasound group,and the differences were statistically significant(P＜0.05).The sensitivity of CL determination in the transvaginal ultrasound group and perineal ultrasound group were significantly higher than that in the transabdominal ultrasound group,and the differences were statistically significant (P＜0.05).The specificity and positive rate of CL determination in transvaginal ultrasound group were significantly higher than those in the transabdominal ultrasound group and perineal ultrasound group,and the differences were statistically significant(P＜0.05).ConclusionThe transabdominal,transvaginal and transperineal ultrasound to determine the CL can effectively predict preterm birth.The sensitivity,specificity and positive rate of transvaginal measurement of CL is higher,worth in the clinical promotion.
2018 Vol. 25 (4): 126-128 [Abstract] ( 162 ) HTML (24 KB)  PDF  (0 KB)  ( 70 )
129 Effect observation of coil ligation in the treatment of cervical polyp bleeding during early pregnancy
CHEN Jie-bo
ObjectiveTo observe the effect of coils ligation in the treatment of cervical polyp bleeding during the early pregnancy,and to explore its clinical value.MethodsA retrospective analysis was made of the diagnosis and treatment data of 63 early pregnancy women occurred with cervical polyps bleeding treated in our hospital from January 2013 to December 2016.They were divided into treatment group (32 cases)and control group (31 cases)according to different treatment methods.The treatment group was treated with cervical polyp coil ligation,and the control group was treated with conservative drug therapy.The duration of vaginal bleeding time,the rate of vaginal bleeding and miscarriage rate were compared between the two groups.ResultsThe duration of vaginal bleeding in the treatment group was shorter than that in the control group,and the rate of vaginal bleeding was lower than that in the control group,the differences were statistically significant(P＜0.05).The rate of miscarriage was compared between the two groups,and the difference was statistically significant(P＞0.05).In the treatment group,the pathological specimens excised during the ligation were all indicative of benign polyps.ConclusionCoil ligation is a safe and feasible method for the treatment of cervical polyps with bleeding in early pregnancy.Besides,the malignant lesions can be excluded,which greatly relieve psychological pressure and effectively improve pregnancy experience.It is worth promotion.
2018 Vol. 25 (4): 129-131 [Abstract] ( 164 ) HTML (27 KB)  PDF  (0 KB)  ( 78 )
132 Observation of clinical effect of balloon cervical dilator and Oxytocin in induction of labor in full-term pregnancies
LI Bi-lin; HE Qing-rong; WANG Yi-gang
ObjectiveTo explore the clinical effect of application of combination of balloon cervical dilator and intravenous Oxytocin injection in induction of labor in full-term pregnancies.MethodsAltogether 120 pregnancies who were diagnosed as full-term pregnancies and would undergo induced labour from October 2016 to October 2017 in our hospital were selected as subjects and divided into two groups according to the random number table method,60 cases in each group.The pregnancies in the control group treated with intravenous injection of 0.5%Oxytocin and pregnancies in the study group treated with balloon cervical dilator combined with intravenous injection of 0.5%Oxytocin.After the treatment,the labor process,mode of delivery,cervical ripening effect and cervical Bishop score were compared between two groups.ResultsAfter the treatment,the labor time and total birth process of study group were significantly shorter than those of control group,and the differences were statistically significant(P＜0.05).The cesarean section rate of the pregnant women in the study group(21.67%)was significantly lower than that in the control group(40.00%),and the difference was statistically significant(P＜0.05).The cervical ripening total effective rate of the pregnant women in the study group(90.00%)was higher than that in the control group(75.00%),and the difference was statistically significant(P＜0.05).The cervical Bishop score of the pregnant women in the study group was higher than that in the control group,and the difference was statistically significant(P＜0.05).ConclusionCombination of application of balloon cervical dilator and intravenous Oxytocin injection is effective and safe for full-term pregnancies,which is worthy of clinical promotion.
2018 Vol. 25 (4): 132-134 [Abstract] ( 185 ) HTML (28 KB)  PDF  (0 KB)  ( 99 )
135 Study on epidemiological characteristics and related risk factors of children′s precocious puberty in Shangrao district
HUANG Jian
ObjectiveTo study and analyze the epidemiological characteristics and related risk factors of precocious puberty in local children.MethodsA total of 125 children with precocious puberty treated in our hospital from March 2015 to March 2017 were selected as the study group and 125 healthy children underwent physical examination in our hospital were selected as the control group.The clinical data of all the subjects were collected and analyzed retrospectively.All subjects were tested for bone age,estradiol,follicle stimulating hormone,test osterone and luteinizing hormone.The related information of two groups of subjects was analyzed to understand the epidemiological characteristics of precocious puberty in children,and the related risk factors was analyzed.ResultsChildren′s precocious puberty was related to the family environment pollution nearby,mother′s occupation,mother′s age of menarche,whether the mother protect fetus during pregnancy,whether parents relationship coordination,whether a family history of premature,living area,birth weight,like emotional shows and novels,eat western fast food,eat nutrition tonic,eat food contains pigment and preservative,eat high protein food and so on (P＜0.05).Living area,liked emotional programs and novels,often eat western fast food,often eat nutrition tonic,often eat food contains pigment and preservative,often eat high protein food were the independent risk factors for children′s precocious puberty (P＜0.05).ConclusionChildren′s precocious puberty affected by many factors,a reasonable diet,proper tending,to create a good environment,can help reduce the occurrence of precocious puberty in children.
2018 Vol. 25 (4): 135-137 [Abstract] ( 194 ) HTML (24 KB)  PDF  (0 KB)  ( 80 )
138 Application effect analysis of ultrasound in the diagnosis of gastric ulcer and gastric cancer
WANG Li-rong
ObjectiveTo investigate the application effect of ultrasound in the diagnosis of gastric ulcer and gastric cancer.Methods80 patients with gastrointestinal diseases(50 cases of gastric ulcer and 30 cases of gastric cancer)admitted to our hospital from July 7,2016 to September 9,2017 were enrolled in this study.All cases were examined by gastroscopy and ultrasonography.The diagnosis of 80 cases of gastrointestinal diseases(diagnosis of disease type,diagnosis of gastric ulcer type,diagnosis of gastric cancer type)were observed and analyzed.ResultsThe accuracy of gastroscopy in diagnosing gastric ulcer was 100.00%and that of gastric cancer was 100.00%.The accuracy rate of ultrasound in diagnosing gastric ulcer was 96.00%and that of gastric cancer was 93.33%.There was no significant difference between the two methods(P＞0.05).Among the 50 patients with gastric ulcer,the results of gastroscopy were 70.00%in the stomach corner,10.00%in the gastric curvature and 20.00%in the gastric curvature.In the ultrasonography results,the gastric corner was 68.00%and the gastric curvature was 10.00%,gastric lesser curvature 18.00%.There was no significant difference between the two methods (P＞0.05).Among the 30 cases of gastric cancer,diffuse infiltration were 66.67%and localized ulcer were 33.33%,respectively.The diagnostic results of ultrasound showed diffuse invasive type were 66.67%and localized ulcer type were 26.67%.There was no significant difference between the two diagnostic methods(P＞0.05).ConclusionUltrasound diagnosis of gastric ulcer and gastric cancer patients has high clinical value.It can not only observe the lesion tissue from multiple angles,multi-body position and multi-level,but also has the advantages of noninvasiveness,safety,less pain,higher diagnosis rate,which is worthy of application and promotion.
2018 Vol. 25 (4): 138-140 [Abstract] ( 161 ) HTML (26 KB)  PDF  (0 KB)  ( 83 )
141 Clinical application of CT-enhanced crown coronal reconstruction in the diagnosis of gastric cancer
LI Mu-zi
ObjectiveTo study the clinical value of CT enhanced crown coronal reconstruction in the diagnosis of gastric cancer.MethodsA total of 200 patients with suspected gastric cancer from January to December in 2016 in our hospital were selected and randomly divided into the control group and the observation group,100 cases in each group.The patients in the control group were scanned with ordinary CT,the patients in the observation group were analyzed by enhanced CT.The diagnostic accuracy of the two groups was compared.ResultsThe diagnostic accuracy rate of the patients in the observation group was significantly higher than that of the control group,with significant difference (P＜0.05).The accuracy of gastric staging in the observation group was relatively higher,in the observation group,the details of the patient′s stomach tumor shape and the relationship between the surrounding organs and other details can be combed clearly.In addition,the degree of metastasis of the patients with gastric cancer can also be more carefully observed.ConclusionThe use of gastric CT enhanced crown coronal reconstruction in the diagnosis of gastric cancer is relatively high accuracy,which was significantly better than that ordinary CT scan,can accurately determine the patient′s disease type.
2018 Vol. 25 (4): 141-143 [Abstract] ( 186 ) HTML (22 KB)  PDF  (0 KB)  ( 75 )
144 Effect of Azithromycine Combined with Gamma Globulin and Rifampicin in the treatment of children with Refractory Mycoplasma pneumoniae pneumonia
LIU Ying-bo;CHEN Yang-hua;LAI Zhong-hua;MEI Hong;ZHANG De-qiong;DENG Mu-yi
ObjectiveTo investigate the effect of Azithromycine Combined with Gamma Globulin and Rifampicin in the treatment of children with Refractory Mycoplasma pneumoniae pneumonia.MethodsFrom March 2012 to March 2016,93 children diagnosed as refractory Mycoplasma pneumoniae pneumonia in our hospital were randomly divided into control group(47 cases)and observation group(46 cases).The control group was treated with azithromycin,while the treatment group was treated with Azithromycin,Gamma globulin and Rifampicin.The curative effect and symptom improvement time were compared between the two groups.ResultsAfter 3 days of treatment,the effective rate of the observation group was significantly better than that of the control group,the difference was statistically significant(P＜0.05);The improvement time of symptoms in the observation group was significantly shorter than that in the control group (P＜0.05).ConclusionAzithromycine combined with Gamma Globulin and Rifampicin in the treatment of children with refractory Mycoplasma pneumoniae pneumonia has better clinical efficiency,with can effectively reduce the symptoms improved time with a high clinical value.
2018 Vol. 25 (4): 144-146 [Abstract] ( 201 ) HTML (28 KB)  PDF  (0 KB)  ( 73 )
147 Clinical study of Oxiracetam combined with Clopidogrel on cerebral protection after reperfusion in patients with acute ischemic stroke
WANG Xin-sheng ;CAI Xuan-kun ;LI Jian-rong ;ZENG Fan-rong; ZENG Xiao-ming
ObjectiveTo Clinical study of Oxiracetam combined with Clopidogrel on cerebral protection after reperfusion in patients with acute ischemic stroke.Methods86 patients with acute ischemic stroke were selected from December 2016 to December 2017.they were divided into control group and study group by random number table method,with 43 cases in each group.The study group was Oxiracetam+Clopidogrel,while the control group was oxiracetam.The changes of neurological deficit score and daily living ability score before and after treatment were compared between the two groups,and the changes of serum malondialdehyde and homocysteine levels were observed.ResultsThere was no significant difference between the two groups(P＞0.05).After treatment,the neurological deficit score of the study group was lower than that of the control group,and the score of daily living ability was higher than that of the control group(P＜0.05).There was no significant difference in serum MDA and homocysteine between the two groups (P＞0.05).After treatment,the level of serum malondialdehyde in the study group was lower than that in the control group,and the level of homocysteine was lower than that in the control group(P＜0.05).ConclusionAcute ischemic stroke patients with Oxiracetam combined with Clopidogrel therapy,cerebral protective effect on reperfusion significantly,and inhibit inflammatory factors,improve neurological function,worthy of further research and promotion.
2018 Vol. 25 (4): 147-149 [Abstract] ( 184 ) HTML (28 KB)  PDF  (0 KB)  ( 83 )
150 Cost effectiveness analysis of fourmedications for primary hepatic carcinoma pain
LAI Yan-jin
ObjectiveTo compare cost effectiveness by Morphine sulfate sustained-release tablets,Oxycodone hydrochloride prolonged-release tablets,Fentanyl transdermal patches and Buprenorphine transdermal patches in the treatment of primary hepatic carcinoma pain.MethodsFrom April 2015 to April 2017,100 patients with pain of primary liver cancer were selected and randomly divided into four groups(A,B,C and D)according to different administration methods,with 25 cases in each group.Group a was given Morphine sulfate sustained release tablets,group B was given oxycodone hydrochloride sustained release tablets,group C was given Fentanyl transdermal patch,group D was given buprenorphine transdermal patch.After treatment for 30 days,the efficacy,adverse reactions and quality of life of the four groups were observed,and cost-effectiveness analysis was carried out.ResultsGroup B and C had higher analgesic effect than group A and D.There was no significant difference in the analgesic effect between the four groups(P＞0.05).there was no significant difference in the incidence of adverse reactions between the four groups after 1 month of drug use (P＞0.05).A-mong them,the adverse reactions in group B(Oxycodone hydrochloride sustained release tablets group)were less.There was significant difference between the four groups before and after treatment(P＜0.001),but there was no significant difference between the four groups(P=0.059).After two-to-two comparison of the four groups,it was found that there was significant difference between group A and group B(P=0.026),group B and group D(P=0.031),the quality of life among the other groups improved,there was no significant difference(P＞0.05);BC/E＜AC/E＜CC/E＜DC/E,there was no significant difference in the efficiency of cost-effect analysis among the four groups(P＞0.05).ConclusionThere were no significant differences in the effective rate of treatment by using four drugs.Compared the adversereactions and quality of life,the oxycodone hydrochloride prolonged-release tablets was the best schedule in the treatment of primary hepatic carcinoma pain from pharmaconomics.
2018 Vol. 25 (4): 150-152 [Abstract] ( 166 ) HTML (28 KB)  PDF  (0 KB)  ( 57 )
153 Clinical application of xuebijing in the treatment of pressure ulcers and Infections
CHEN Zheng; LING Shao-jun; ZHANG Jun-hong
ObjectiveTo analyze the clinical effect of Xuebijing in the treatment of pressure ulcers and infections.MethodsFrom April 2015 to December 2016,74 patients with pressure sore were selected and divided into control group and treatment group according to the order of treatment.37 patients in each group were treated with conventional antibiotic oral plus wound debridement and dressing change treatment.The treatment group was combined with Xuebijing injection,and the therapeutic effect of the two groups was analyzed.ResultsAfter 7 days of treatment,the body temperature,C-reactive protein level and white blood cell level in the treatment group were significantly lower than those in the control group(P＜0.05).The follow-up observation showed that the wound healing rate of the treatment group was higher than that of the control group (P＜0.05),while The wound healing time of the treatment group([33.75±3.95]d)was shorter than that of the control group([40.30±3.68]d),the difference was statistically significant(t=7.3801,P=0.0000).ConclusionThe clinical application of Xuebijing in the treatment of pressure ulcers and infections in diabetic patients achieves good and clear effect.
2018 Vol. 25 (4): 153-155 [Abstract] ( 183 ) HTML (25 KB)  PDF  (0 KB)  ( 71 )
156 The curative effect detection of treatment severe pneumonia by Sulperazon union Avelox
ZHANG Xiao-jun;YE Jian-ting;CHEN Hua
ObjectiveTo approach curative effect of treatment severe pneumonia by Sulperazon union Avelox.Methods68 patients with severe pneumonia admitted to our hospital from March 2013 to March 2016 were selected,According to the different treatment measures were divided into the control group(Sulperazon alone)30 cases and the combined treatment group (Sulperazon combined with Avelox treatment)38 cases.The plasma index and white blood cell count of two groups of patients with severe pneumonia before and after treatment were observed,and the clinical efficacy and adverse reactions of two groups of patients with severe pneumonia were observed.ResultsThere was no significant difference in pct,WBC and CRP between the two groups before treatment(P＞0.05).After treatment,the levels of pct,WBC and CRP in the control group and the combined treatment group were lower than those before treatment(P＜0.05).Pct,WBC and CRP in the combined treatment group were significantly lower than those in the control group(P＜0.05).The clinical total effective rate of severe pneumonia patients in the combined treatment group was higher than that in the control group,and the difference was statistically significant(P＜0.05).There was no significant difference in the incidence of nausea,diarrhea and dizziness between the two groups(P＞0.05).ConclusionThe treatment severe pneumonia by Sulperazon union Avelox,clinical effects is obviously,PCT and WBC、CRP are obviously decreasing,untoward effect is little,it is worth to be used.
2018 Vol. 25 (4): 156-158 [Abstract] ( 217 ) HTML (26 KB)  PDF  (0 KB)  ( 70 )
159 Clinical effect of Alprostadilin dry emulsion combined with Warfarin in the treatment of thrombophlebitis of lower extremities
XIE Ying-chun ;LUO Yuan-hui;LIU Yi-xue
ObjectiveTo investigate the clinical effect of alprostadilin dry emulsion combined with warfarin in the treatment of thrombophlebitis of lower extremities.Methods48 patients with lower extremity thrombophlebitis admitted to our hospital from January 2014 to January 2017 were divided into control group and observation group according to random number table,with 24 cases in each group.Patients in the control group were treated with alprostadil dry emulsion,while patients in the study group were treated with warfarin on the basis of the control group.The clinical efficacy and time of disease elimination were compared between the two groups.ResultsThe effective rate of treatment in the study group was significantly better than that in the control group (P＜0.05),and the disappearance time of clinical symptoms in the study group was significantly shorter than that in the control group(P＜0.05).ConclusionIn the clinical treatment of thrombophlebitis of lower extremities,combination of alprostadilin dry emulsion and warfarin can greatly increase the cure rate and shorten the therapeutic process.
2018 Vol. 25 (4): 159-161 [Abstract] ( 164 ) HTML (24 KB)  PDF  (0 KB)  ( 71 )
162 Clinical observation of ultrasonic aerosol inhalation of hypertonic saline,Ribavirin and Dexamethasone in the treatment of acute laryngopharyngitis
LI Yao-yao
ObjectiveTo explore the clinical effect of ultrasonic aerosol inhalation of hypertonic saline,Ribavirin and Dexamethasone in the treatment of acute laryngopharyngitis.Methods60 patients with acute pharyngolaryngitis admitted to our hospital from January to October 2017 were divided into control group and observation group according to the random number table,with 30 cases in each group.The observation group was treated with hypertonic saline+Ribavirin+Dexamethasone atomization inhalation,while the control group was treated with normal saline+Ribavirin+Dexamethasone atomization inhalation.The effects of different atomization on the therapeutic effect and the time needed to improve the symptoms of pharyngeal itching,sore throat,cough and hoarseness were compared between the two groups.ResultsThe total effective rate of clinical treatment in the observation group was higher than that in the control group(P＜0.05),and the time required for the improvement of symptoms in the observation group was significantly shorter than that in the control group (P＜0.05).ConclusionIn patients with acute sore throat atomization inhalation of hypertonic saline with drug treatment,can significantly improve the clinical total effective rate,shorten the time needed for symptoms improved,this method is worthy of application and promotion.
2018 Vol. 25 (4): 162-164 [Abstract] ( 194 ) HTML (24 KB)  PDF  (0 KB)  ( 101 )
165 Adverse reactions comparison of Methimazole and Propylthionracil in the treatment of hyperthy roidism
ZHANG Han
ObjectiveTo investigate the effect of Methimazole and Propylthiouracil on adverse reactions in patients with hyperthyroidism.MethodsFrom February 2006 to February 2016,600 patients with hyperthyroidism were divided into study group and control group by random number table method,with 300 cases in each group.The study group was treated with methimazole and the control group with propylthiouracil.The incidence of adverse reactions was compared between the two groups.ResultsThe incidence of leukopenia,granulocytopenia and rash in the study group was significantly higher than that in the control group(P＜0.05).The abnormal rate of liver function in the study group was significantly lower than that in the control group (P＜0.05).ConclusionMethimazole and Propylthiouracil may produce different adverse reactions in patients with hyperthyroidism.Methimazole easily leads to the decrease of white blood cells,erythrocytes and thrombocytopenia,and propylthiouracil easily leads to abnormalities of various indexes of liver function.
2018 Vol. 25 (4): 165-167 [Abstract] ( 212 ) HTML (24 KB)  PDF  (0 KB)  ( 72 )
168 Efficacy and application of Xingnaojing Injection in treatment of mental retardation in convalescence of stroke
LUO Hua-wen
ObjectiveTo investigate the effect of Xingnaojing Injection in treatment of mental retardation in convalescence of stroke.Methods106 patients with stroke complicated with dysgnosia from January 2014 to December 2016 were selected as object,and they were divided into the two groups according to the random number table method,and there were 53 cases in each group.Two groups were given routine symptomatic treatment,and observation group was treated with Xingnaojing Injection based on the routine treatment.The curative effect,degree of lethargy,degree of intellectual disability,degree of nerve function defect and adverse reactions were compared between the two groups.ResultsThe total effective rate of observation group(96.23%)was higher than control group(81.13%)(P＜0.05).After 7 d and 14 d treatment,the scores of GCS and MMES in the observation group were higher than those in the control group(P＜0.05).After treatment,NIHSS score of the observation group was lower than that of the control group,and the difference had statistical significance (P＜0.05).After treatment,the score of activity of daily living in the observation group was higher than that in the control group (P＜0.05).ConclusionXingnaojing Injection in treatment of mental retardation in convalescence of stroke is effective,and it can effectively promote the recovery of nerve function and intelligence,improve the state of drowsiness of patients,be beneficial to the prognosis,and the druguse is safe and reliable.
2018 Vol. 25 (4): 168-170 [Abstract] ( 181 ) HTML (26 KB)  PDF  (0 KB)  ( 35 )
171 Application of Zhengqing Fengtongning via electroporation to Shenshu and Qiu acupoint in the treatment of renal colic
LI Bo; HU Yan; LIU Min-ping; WU Guan-tu
ObjectiveTo verify the clinical effect of Zhengqing Fengtongning via electroporation to Shenshu and Qiu acupoint in the treatment of renal colic.MethodsA total of 75 inpatients with renal colic treated in our hospital from September 2016 to September 2017 were screened as research objects.They were randomly divided into the experimental group,control group A and control group B,and there were 25 patients in each group.In the experimental group,Zhengqing Fengtongning via electroporation to Shenshu and Qiu acupoint was applied,while in the control group A,Flurbiprofen Axetil injection for intravenous dripping,and in the control group B,normal saline via electroporation to Shenshu and Qiu acupoint was adopted.VAS score,score of pain relief maintenance time,and score of abdominal plain film,B ultrasound in urinary system,and renal function evaluation before and after treatment were compared in order to evaluate the effect.ResultsVAS score,score of pain relief maintenance time,and score of abdominal plain film,B ultrasound in urinary system,and renal function evaluation among the three groups after treatment were all significantly lower than those before therapy.The score of these indexes in the experimental group were greatly lower than those in the control group A and B(P＜0.05).The total effective rate was 92.0%in the treatment group,and 68.0%in control group A and 56.0%in the control group B,and the curative effect in the experimental group was significantly better than that in the control group (P=0.024).ConclusionZhengqing Fengtongning via electroporation to Shenshu and Qiu acupoint in the treatment of renal colic can obtain a remarkable effect,which provide scientific basis for clinical application and promotion.
2018 Vol. 25 (4): 171-173转176 [Abstract] ( 184 ) HTML (30 KB)  PDF  (0 KB)  ( 114 )
174 Application effect of high quality nursing in postpartum hemorrhage in women suffering from pregnancy-induced hypertension syndrome
GUI Shao-zhen
ObjectiveTo analyze the clinical effect of high quality nursing in postpartum hemorrhage in women suffering from pregnancy-induced hypertension syndrome.MethodsFrom January 1,2015 to July 31,2017,a total of 55 puerperae suffering from pregnancy-induced hypertension syndrome visited our hospital due to postpartum hemorrhage were selected.They were randomly divided into observation group and reference group.In the reference group(n=27),routine nursing was used,while in the observation group(n=28),high-quality nursing was applied.The nursing effect of the two groups was compared.ResultsThe amount of bleeding in the observation group was lesser than that in the reference group,and the nursing satisfaction in the observation was higher,which were displayed statistical differences after intergroup comparisons(P＜0.05).ConclusionFor pregnancy-induced hypertension syndrome puerperae with postpartum hemorrhage,application of high quality nursing can obtain a remarkable effect.It can reduce the intraoperative amount of bleeding and improve the nursing satisfaction,which is worthy of clinical application and promotion.
2018 Vol. 25 (4): 174-176 [Abstract] ( 208 ) HTML (24 KB)  PDF  (0 KB)  ( 73 )
177 Influence of Lamaze delivery combined with nursing intervention on labor pain，labor progress，and spontaneous delivery rate
JIANG Peng-ying; LIU Hui-qin
Objective To analyze the influence of Lamaze delivery combined with nursing intervention on labor pain，labor progress,and spontaneous labor rate.MethodsA total of 60 pregnant women visited our clinics in our hospital from May 2014 to August 2015 were selected as observation objects.By a random number table,they were divided into control group(n=30)and observation group(n=30).The nursing and pregnancy care by obstetrical clinics and pregnancy school were applied in both groups.Besides,regular nursing was provided in the control group,and Lamaze labor breathing training was adopted in the observation group.The SPSS 17.0 analysis was used to analyze the spontaneous rate,labor duration,and pain tolerance,and so on.ResultsThe rate of spontaneous delivery in the observation group was higher than that in the control group with a statistical difference(P＜0.05).The degree of pain in the observation group was significantly decreased compared with that in the control group(P＜0.05).The duration of labor(including first,second,and total labor)in the observation group was markedly shorter in comparison with that in the control group,which was displayed a statistical difference(P＜0.05).ConclusionCombination of Lamaze delivery and nursing intervention is beneficial to reduce the pain degree of pregnant women,promote the labor process,and increase the rate of spontaneous delivery.
2018 Vol. 25 (4): 177-179 [Abstract] ( 208 ) HTML (26 KB)  PDF  (0 KB)  ( 70 )
180 Influence of continuous nursing on illness cognition，self-management skill，recurrence in patients with urinary calculi
SHI Xian-rong
ObjectiveTo investigate the influence of continuous nursing on illness cognition，self-management skill and recurrence in patients with urinary calculi.Methods80 patients with urinary calculi admitted into the hospital from June to December 2015 were selected as the control group,and 80 patients with urinary calculi admitted into the hospital from January to July 2016 were selected as the observation group.Patients in the control group was given routine nursing,while patients in the observation group was given continuous nursing based on the control group.The illness cognition,self-management skill and recurrence in two groups were observed.ResultsThe cognitive rate of observation group(93.75%)was higher than that of control group(82.50%),with statistical difference(P＜0.05).The obeying doctors′advice，drinking and diet,exercise,weight control,regular examination in the observation group were better than those in the control group,but the recurrence rate in observation group was lower than that in control group,with statistical differences(P＜0.05).ConclusionContinuous nursing in patients with urinary calculi can increase the rate of illness cognition,enhance the self-management skill of patients and effectively reduce the recurrence rate.
2018 Vol. 25 (4): 180-182 [Abstract] ( 176 ) HTML (26 KB)  PDF  (0 KB)  ( 75 )
183 The effect of body position nursing in the process of expectant mothers
BI Yan;BI Yi
ObjectiveTo study on application effect of posture nursing in maternal labor process in.Methods100 cases of pregnant women from August 5,2016 to August 6,2017 in our hospital as the research object,according to the labor were divided into control group and was observation group,50 cases in each group.The control group was implemented routine position labor,the observation group used nursing mode of labor.The delivery mode，postpartum hemorrhage,pain,birth process time and neonatal asphyxia rate were observed in two groups of parturients.ResultsThe rate of the two groups of maternal natural childbirth,the observation group was higher than that the control group(P＜0.05);the pain scores were compared between the two groups,the observation group was lower than that the control group(P＜0.05);the two groups were compared in the labor time,the observation group was shorter than that the control group(P＜0.05);asphyxia comparison of rate and neonatal hemorrhage of two groups of maternal postpartum,the observation group was lower than that the control group,the differences were statistically significant(P＜0.05).ConclusionStrengthening the nursing position helps to shorten the birth process and improve birth outcomes in maternal labor process,to improve the natural birth rate and the quality of delivery.
2018 Vol. 25 (4): 183-185 [Abstract] ( 161 ) HTML (25 KB)  PDF  (0 KB)  ( 67 )
186 Effect of PDCA nursing model on reducing complications of patients with craniocerebral trauma
XU Ran-dan; LIN Xiu-hua ;ZHANG Hong-rong ;XIE Xuan
ObjectiveTo investigate the effect of PDCA nursing model on reducing the complication of traumatic brain injury.MethodsFrom March 2015 to February 2017,117 patients with craniocerebral trauma in our hospital were selected as the subjects,and the patients were divided into two groups according to the time of admission.The control group(n=60)was treated with conventional care.The observation group(n=57)was used PDCA nursing mode to intervene.The incidence of complications,Glasgow Coma Scale（GCS） score,Barthel score,National Institute of Health Stroke Scale（NIHSS）,and nursing satisfaction were compared between the two groups.ResultsAfter intervention,the incidence of patients with observation,NIHSS score was lower than that the control group of patients,while the GCS score,Barthel score and nursing satisfaction were higher than that the control group,the differences were statistically significant(P＜0.05).ConclusionPDCA nursing model has a positive effect in the care of patients with craniocerebral trauma,which can help to reduce the incidence of complications,improve the patient′s condition and improve the nursing satisfaction.It is worthy of clinical promotion.
2018 Vol. 25 (4): 186-188 [Abstract] ( 177 ) HTML (26 KB)  PDF  (0 KB)  ( 91 )
189 Effect of nursing intervention on transfer of caesarean section for pregnancies with gestational hypertension undergoing epidural labor analgesia
CHEN Qiu-hua; LIU Fen; GONG Chun-hong
ObjectiveTo investigate the effect of nursing intervention on transfer of caesarean section for pregnancies with gestational hypertension undergoing epidural labor analgesia.MethodsAltogether 122 cases of pregnancies with gestational hypertension who underwent epidural labor analgesia and were transferred for cesarean section from February 2013 to February 2017 were selected as the subjects of this research and divided according to the difference between the single and even number of wards into two groups,61 cases in each group.The control group was received routine nursing care;while,the experiment group was treated with nursing intervention.The systolic pressure at instant uterine contraction(T0),instant analgesia(T1),30 minutes after labor analgesia(T2),before transfer of cesarean section(T3),at instant anesthesia(T4),skin incision(T5)and the completion of the operation(T6)were compared between two groups.ResultsDuring analgesia,the systolic pressure indexes of the experiment group at T1,T2and T3were lower than those of the control group,the diastolic pressure indexes at T2and T3were lower than those of the control group,with statistically significant difference(P＜0.05);the systolic pressure at T0and diastolic blood pressure at T0and T1of two groups had no statistically significant difference(P＞0.05).During the cesarean section,the systolic pressure and diastolic pressure at T4,T5and T6 of the experiment group were lower than those of the control group,with statistically significant difference(P＜0.05).ConclusionApplication of nursing intervention in pregnancies with gestational hypertension undergoing epidural labor analgesia for transfer of caesarean section can effectively control blood pressure and improve clinical symptoms,which is of great promotion value.
2018 Vol. 25 (4): 189-191转194 [Abstract] ( 251 ) HTML (30 KB)  PDF  (0 KB)  ( 67 )
192 Influence of humanistic nursing care on health knowledge and nursing satisfaction of patients with renal calculi surgery
ZHANG Qian;MENG Yang;YIN Lei;LI Ya-lang;LI Wei-bo;KANG Ning
ObjectiveTo analyze the effects of humanistic care on health knowledge and nursing satisfaction of patients with renal calculi surgery.Methods100 cases of renal stone surgery patients admitted to our hospital from May 25,2016 to June 28,2017 were selected as the research subjects.They were randomly divided into control group (routine nursing intervention)and observation group (implementation of humanistic care care),50 cases in each group.The health knowledge satisfaction score and the compliance of the two groups were compared，and the time of hospitalization,the satisfaction of nursing and the mental state were compared.ResultsThe scores of health knowledge satisfaction([95.65±1.23])score,surgical treatment compliance score([96.68±1.15])score and hospitalization time([6.23±1.02]d)in the observation group were significantly better than that those in the control group,the differences were statistically significant(P＜0.05).The nursing satisfaction of the patients in the observation group was 98%higher than that of the control group,and the difference was statistically significant(P＜0.05).The mental state score of the patients in the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).ConclusionHumanistic care for patients with renal calculi surgery can improve their health knowledge score,and improve their anxiety and depression,and improve their satisfaction.
2018 Vol. 25 (4): 192-194 [Abstract] ( 198 ) HTML (26 KB)  PDF  (0 KB)  ( 96 )
195 Effect analysis of early comprehensive rehabilitation nursing in ischemic stroke
LI Hai-xia ;CHEN Xiao-shan;MA ZHI-fen; LI Pei-fen
ObjectiveTo observe and analyze the clinical efficacy of early comprehensive rehabilitation nursing for patients with ischemic stroke.MethodsFrom September 2015 to October 2016,100 patients with ischemic stroke in acute stage were selected,they were randomly divided into two groups according to the order of admission,50 cases in each group.The control group was treated with general clinical therapy combined with conventional rehabilitation nursing;the observation group in the control group on the basis of was used the joint rehabilitation nursing,including Medium frequency electrotherapy,the air pressure wave therapy,electronic biofeedback treatment.The recovery of exercise ability(FMA)and the recovery of daily living ability(ADL)were observed in the two groups before and after the nursing care,and the nursing effect was evaluated.ResultsFMA score of the observation group was(22.1±8.1)points,ADL score was(38.1±8.5)points before treatment and the control group were(21.7±18.9),(37.7+8.4)points,the differences were not statistically significant(P＞0.05),after rehabilitation nursing,FMA score of the observation group was(74.6±24.4)points,ADL score was(74.6±10.4)points and FMA score of the control group was(64.7±21.5)points,ADL score was(66.6±6.4)points,the differences were statistically significant(P＜0.05).ConclusionThe comprehensive rehabilitation nursing for the patients with ischemic stroke has good clinical efficacy,the exercise ability and self-care ability of the patients have been improved effectively,and the clinical application value is higher.
2018 Vol. 25 (4): 195-197 [Abstract] ( 166 ) HTML (23 KB)  PDF  (0 KB)  ( 82 )
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