老年高血压合并抑郁患者抗抑郁治疗后的血压改变情况分析

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Abstract ObjectiveTo investigate the changes of blood pressure in elderly patients with hypertension and depression after antidepressant treatment.MethodsAltogether 168 cases of elderly patients with hypertension and depression who were diagnosed and treated in our hospital from January 2015 to December 2016 were selected as the subjects,and divided into the observation group and the control group according to the random number table method,84 cases in each group.The observation group was given Duloxetine,and the control group was given Duloxetine analog medicine.The course of treatment was 4 weeks.The treatment effect of blood pressure,pre-operational and post-operational Hamilton Anxiety Scale(HAMA),Hamilton Depression Scale(HAMD),diastolic and systolic blood pressure and intra-operational adverse reactions were compared between the two groups.ResultsThe total effective rate of blood pressure treatment of the observation group (95.24%)was higher than that in the control group (85.71%),with statistically significant difference (P＜0.05).There was no statistically significant difference in pre-operational HAMA,HAMD and diastolic blood pressure and systolic blood pressure between the two groups (P＞0.05).The post-operational HAMD,HAMA,diastolic blood pressure and systolic blood pressure of two groups of patients were significantly decreased,and the difference was statistically significant between the two groups(P＜0.05).There was no statistically significant difference in incidence of adverse reactions(P＞0.05).ConclusionAntidepressant treatment can reduce the blood pressure level in elderly patients with hypertension and depression.

Key words： Elderly Hypertension Depression Antidepressant treatment

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	HE Zhi-qiu
	CHEN Yi

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HE Zhi-qiu,CHEN Yi. Analysis of blood pressure changes in elderly patients with hypertension and depression after anti-depressant treatment[J]. 中国当代医药, 2018, 25(4): 41-43.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I4/41

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