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| Observation on application of restrictive transfusion in the treatment of acute upper gastrointestinal hemorrhage |
| CHEN Shao-wu DENG Shi-rong QU Chang-chun GAN Guo-neng |
| Intensive Care Unit,Yunfu People′s Hospital in Guangdong Province,Yunfu 527300,China |
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Abstract ObjectiveTo investigate the effect of restrictive transfusion in the treatment of acute upper gastrointestinal bleeding.Methods78 patients with acute upper gastrointestinal bleeding treated in our department from January 2014 to October 2016 were selected as the subjects,and divided into control group and observation group,39 cases in each group according to the random principle.In the control group,conventional open positive blood transfusion was used,while in the observation group,restrictive transfusion was adopted.The rate of hemostasis at 24,48 and 72 h,and incidence of adverse reactions after transfusion were compared between the two groups.At the same time,the risk of rebleeding was assessed by Blatchford scoring system.ResultsWithin 24 hours,the rate of hemostasis in the observation group was 28.21%,much higher than that in the control group accounting for 10.26%,and the difference was statistically significant(P＜0.05).The rates of hemostasis at 48 h and 72 h were 48.72%and 84.62%in the observation group,while in the control group,they were 41.03%and 79.49%respectively,without statistical difference (P＞0.05).In comparison of adverse reaction,the total incidence of adverse reactions in the observation group(33.33%)was much lower than that in the control group(53.85%),the difference was statistically significant(P＜0.05).In the Blatchford scoring,the score in the observation group was (2.89±0.75)points,significantly lower than that in the control group for(3.69±0.81)points,the difference was statistically significant(P＜0.05).ConclusionIn patients with acute upper gastrointestinal hemorrhage for transfusion,restrictive mode can be selected.It can not only increase the hemostatic rate but also reduce the risk of rebleeding.Besides,it can also reduce the incidence of adverse reactions during blood transfusion as well as the amount of blood transfusion in clinic,which is worthy of promotion.
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