高通量血液透析对尿毒症患者毒副代谢产物及钙磷代谢的影响

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Abstract ObjectiveTo study the improvement role of high flux hemodialysis(HFHD)on the toxic and metabolic products and calcium and phosphorus metabolism for uremic patients.MethodsThe 80 uremic patients in our hospital during the period from January 2016 to December were randomized into the control group(CHD)and the observation group(HFHD),40 patients in each group.The serum changes of toxic and metabolic product,calcium and phosphorus metabolism on pre-and post-dialysis were detected and compared in two groups.ResultsCompared with the CHD group,the levels of beta2-microglobulin (β2-MG)and soluble transferrin receptor(sTfR)were significantly reduced on post-dialysis in the HFHD group with statistical difference(P＜0.05);compared with the CHD group,the levels of serum phosphorus(P),parathyroid hormone(PTH),alkaline phosphatase(AKP)were obviously decreased on post-dialysis in the HFHD group with statistical difference(P＜0.05).ConclusionThe HFHD can effectively eliminate toxins for uremic patients and improve the abnormal state of calcium and phosphorus metabolism.

Key words： High flux hemodialysis Uremia Metabolism of calcium and phosphorus Toxin

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	Articles by authors
	GUO Bao-chun
	WANG Kang
	ZHANG Xin-zhou

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GUO Bao-chun,WANG Kang,ZHANG Xin-zhou. The improvement role of high flux hemodialysis on the toxic and metabolic products and calcium and phosphorus metabolism for uremic patients[J]. 中国当代医药, 2018, 25(4): 80-82.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I4/80

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