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2020 Vol. 27, No. 33 Published: 2020-11-28

	4	Comparison of the clinical effect of loop electrosurgical excision procedure and cold knife conization in the treatment of cervical epithelial neoplasia
		WANG Yu-ying；YUAN Ye；ZHAO Chun-yan
		Objective To compare the clinical effect of loop electrosurgical excision procedure (LEEP) and cold knife conization (CKC) in the treatment of cervical intraepithelial neoplasia.Methods From May 2016 to May 2018 in the Third Affiliated Hospital of Xuzhou Medical University，a total of 200 patients with cervical intraepithelial neoplasia were selected as the research subjects，they were divided into the observation group (100 cases) and the control group (100 cases) according to the method of drawing lots.The observation group was treated with LEEP，while the control group was treated with CKC.The operation time，intraoperative bleeding volume，postoperative bleeding volume，cervical repair time，vaginal discharge time，postoperative high-risk HPV infection rate and hospitalization time of the two groups were recorded.The postoperative pregnancy，premature delivery，premature rupture of membranes，cesarean section，asphyxia neonatorum，low birth weight infants，postpartum hemorrhage，cervical injury，reproductive tract infection and the incidence of complications of the two groups were compared The heart rate，the self-rating anxiety scale (SAS)score，white blood cell count (WBC) and C-reactive protein (CRP) levels of the two groups were observed before and after operation.Results The operation time，cervical repair time and hospitalization time of the observation group were shorter than those of the control group，the intraoperative and postoperative bleeding volume of the observation group were less than those of the control group，and the postoperative high-risk HPV infection rate of the observation group was lower than that of the control group，the differences were statistically significant (P＜0.05).There was no significant difference in vaginal discharge time between the two groups (P＞0.05).The levels of CRP，WBC and heart rate of the two groups after operation were higher than those before operation，and the levels of CRP，WBC and heart rate of the observation group after operation were lower than those of the control group，the differences were statistically significant (P＜0.05).The SAS score of the two groups after operation was lower than that before operation，and the SAS score of the observation group after operation was lower than that of the control group，the differences were statistically significant (P＜0.05).The postoperative pregnancy rate of the observation group was higher than that of the control group，and the incidence of low birth weight infants，premature rupture of membranes and reproductive tract infection rate of the observation group were lower than those of the control group，the differences were statistically significant (P＜0.05).There was no significant difference in the total incidence of postoperative complications between the observation group and the control group (P＞0.05).Conclusion LEEP is better than CKC in the treatment of cervical epithelioid lesions，and it can effectively reduce the incidence of adverse pregnancy and has high safety.It is worthy of clinical promotion.
		2020 Vol. 27 (33): 4-8 [Abstract] ( 25 ) HTML (43 KB) PDF (0 KB) ( 9 )

	9	Clinical effect of targeted drug Apatinib assisted three-dimensional conformal intensity-modulated radiotherapy in the treatment of elderly patients with non-small cell lung cancer
		WU Xiao-ling；YANG Yu；MA Gao-jian；MA Qing-mei
		Objective To investigate the clinical effect of targeted drug Apatinib assisted three-dimensional conformal intensity-modulated radiotherapy in the treatment of elderly patients with non-small cell lung cancer.Methods A total of 80 cases of elderly patients with non-small cell lung cancer who were treated in Yancheng Second People′s Hospital from January 2017 to December 2019 were selected as the subjects，and they were divided into the observation group and the control group using the random number table method，40 cases in each group.The control group was given three-dimensional conformal intensity-modulated radiotherapy，the observation group was given Apatinib on the basis of the control group，the total clinical effective rate，serum carcinoembryonic antigen (CEA) and vascular endothelial growth factor (VEGF) levels before and after treatment and incidence of adverse reactions of the two groups were compared.Results One month after the end of the treatment，the total clinical effective rate of the observation group was 62.5%，which was higher than that of the control group (45.0%)，the difference was statistically significant (P＜0.05).After treatment，compared with before treatment，the serum CEA and VEGF levels of the two groups decreased，and the serum CEA and VEGF levels of the observation group were lower than those of the control group，the differences were statistically significant (P＜0.05).The main adverse reactions of the two groups were hypertension，hemorrhage，gastrointestinal reaction，hemoglobin reduction，leucopenia and liver and kidney dysfunction.The total incidence rate of adverse reactions in the observation group was 17.5%，which was lower than that in the control group (37.5%)，the difference was statistically significant (P＜0.05).Conclusion The effect of Apatinib in the combination with three-dimensional conformal intensity-modulated radiotherapy in the treatment of elderly patients with non-small cell lung cancer is definite，the serum CEA and VEGF levels are significantly improved，the adverse reactions are few，and the therapeutic effect is significant，which is worthy of clinical application.
		2020 Vol. 27 (33): 9-12 [Abstract] ( 28 ) HTML (37 KB) PDF (0 KB) ( 10 )

	13	Application effect of Linaclotide combined with Compound Polyethylene Glycol Electrolytes Powder in bowel preparation for colonoscopy
		WANG Wei；WEN Qiao-sheng
		Objective To explore the application effect and safety of Linaclotide combined with Compound Polyethylene Glycol Electrolyte Powder in bowel preparation before colonoscopy.Methods A total of 156 patients who underwent colonoscopy in Suzhou Kowloon Hospital Affiliated to Shanghai Jiao Tong University School of Medicine from January to June 2020 were selected as study objects and divided into the control group，observation group A and observation group B by random number table method，with 52 cases in each group.The control group was given 3 bags of Compound Polyethylene Glycol Electrolyte Powder to clear the intestines，the observation group A was given Linaclotide combined with 2 bags of Compound Polyethylene Glycol Electrolyte Powder to clear the intestine，and the observation group B was given 2 bags of Compound Polyethylene Glycol Electrolyte Powder to clear the intestine.Intestinal cleanliness and the incidence of adverse reactions of patients in each group were compared.Results The scores of left semicolon，transverse colon，right semicolon and total Boston bowel preparation-aration scale (BBPS) in observation group B were lower than those in the control group，and the differences were statistically significant (P＜0.05).There were no statistically significant differences in the scores of left semicolon，transverse colon，right semicolon and total BBPS between the observation group A and the control group (P＞0.05).The scores of left semicolon，transverse colon，right semicolon and total BBPS in observation group A were higher than those in the obeservation group B (P＜0.05).The total incidence of adverse reactions in observation group A and observation group B were both lower than those in the control group，and the differences were statistically significant (P＜0.05).There was no statistically significant difference in total incidence of adverse reactions between observation group A and observation group B (P＞0.05).Conclusion The intestinal preparation effect of Linaclotide combined with 2 bags of Compound Polyethylene Glycol Electrolyte Powder is approximately the same as that of 3 bags of Compound Polyethylene Glycol Electrolyte Powder，and it can reduce the total incidence of adverse reactions in the process of intestinal preparation，and has higher safety.Its intestinal cleaning effect is also better than that of 2 bags of Compound Polyethylene Clycol Electrolyte Powder.
		2020 Vol. 27 (33): 13-16 [Abstract] ( 23 ) HTML (38 KB) PDF (0 KB) ( 9 )

	17	Study on the inhibitory effect of XPO4 gene on human liver cancer cells
		WU Nan；LIU Kan；WANG Xiao-mei
		Objective To construct a vector expressing tumor suppressor gene XPO4 and observe its inhibitory effect on liver cancer cells.Methods The XPO4 gene was inserted into the eukaryotic expression vector pcDNA3.1 to construct the tumor suppressor gene expression vector pcDNA3.1-XPO4.Transfection of hepatocellular carcinoma cell line SKHep1 was performed in vitro.The XPO4 gene expression was observed by Western Blot，and tumor cell inhibition was detected by cell counting kit-8(CCK-8)and Annexin V/PI.Results The pcDNA3.1-XPO4 plasmid vector constructed in this study was transfected into SK-Hep1 cells in vitro，and can effectively promote the expression of tumor suppressor gene XPO4 in cells.The cell survival rate of the recombinant plasmid PCDNA3.1-XPO4 transfection group was lower than that of the SK-Hep1 cell control group and the pcDNA3.1 empty plasmid transfection group，and the differences were statistically significant (P＜0.001).The early apoptosis rate of the recombinant plasmid pcDNA3.1-XPO4 transfection group ([13.89±1.62]%) was higher than that of the SK-Hep1 cell control group ([5.14±1.13]%) and the pcDNA3.1 empty plasmid transfection group ([5.79±2.11]%)，and the differences were statistically significant (P＜0.001).Conclusion XPO4 tumor suppressor gene expression can significantly inhibit the proliferation of SK-Hep1 tumor cells and induce cell apoptosis，indicating that XPO4 may play an important role in the occurrence and development of hepatocellular carcinoma，and may become a potential method for diagnosis and treatment of hepatocellular carcinoma.
		2020 Vol. 27 (33): 17-20 [Abstract] ( 26 ) HTML (36 KB) PDF (0 KB) ( 10 )

	21	Clinical research progress on prevention and treatment of knee osteoarthritis by different acupuncture therapies
		LIU Lang；AN Lu；MO Yi-fang；ZHAO Wen-hai；ZHAO Chang-wei
		Knee osteoarthritis is the most common chronic disease in the department of orthopedics and traumatology.It is one of the main causes of pain，dysfunction and disability，which greatly reduces the quality of life of patients.The majority of patients can obtain satisfactory curative effect by conservative treatment of traditional Chinese medicine.Among them，acupuncture and moxibustion is one of the commonly used treatment methods.It has the characteristics of high safety，no side effects，simple operation，etc.It can effectively treat pain and dyskinesia of patients and has been widely used in clinic.This article will analyze the characteristics of acupuncture and moxibustion therapy at home and abroad in recent years from the perspective of different acupuncture and moxibustion therapies，and provide new treatment ideas for clinical prevention and treatment of knee osteoarthritis.
		2020 Vol. 27 (33): 21-24 [Abstract] ( 28 ) HTML (47 KB) PDF (0 KB) ( 11 )

	25	Research progress on the role of bone morphogenetic proteins in tumor
		WU Na-wei；WU Fa-ming；LIU Zhao-qi；JIN Jin-lian
		Bone morphogenetic proteins (BMPs) are important members of the transforming growth factor-β (TGF-β)family，which widely exist in a variety of human tissues and cells，and participate in the occurrence，development and metastasis of tumors.Because of the diversity of its functions，BMPs have become the focus of tumor targeted therapy research.Based on the current research，this article reviews the biological characteristics of BMPs，the relationship between BMPs and tumors，the treatment and prognosis of BMPs and tumors.
		2020 Vol. 27 (33): 25-28 [Abstract] ( 26 ) HTML (39 KB) PDF (0 KB) ( 10 )

	29	Effect of miR-34a-Sirt1-NRF2 signal pathway on the proliferation of endogenous neural stem cells after cerebral ischemic injury
		LIAO Wei；CAI Chong-ming；WANG Hai-bin；CHENG Wei；ZENG Zhao-bin；YANG Shao-chun
		Objective To explore the effect of miR-34a-Sirt1-Nrf2 signal pathway on the proliferation of endogenous neural stem cells after cerebral ischemia injury.Methods Rats with modified focal middle cerebral artery embolism(MCAO) cerebral ischemia were prepared，and they were set as cerebral ischemia 1 d group(n=10)，cerebral ischemia 3 d group (n=10)，cerebral ischemia 7 d group (n=10)，resveratrol group (n=10)，and rats without ischemic treatment were also set up as control group (n=10).The expression levels of mir-34a，Sirt1，NRF2 in the subventricular zone of rats in each group were detected by RT-PCR.Results Compared with the control group，the relative expression of miR-34a mRNA in the resveratrol group，cerebral ischemia 1 d group，cerebral ischemia 3 d group and cerebral ischemia 7 d group increased，while the relative expression of Sirt1 and NRF2 protein decreased，the differences were statistically significant (P＜0.05).Compared with the resveratrol group，the relative expression of miR-34a mRNA in the cerebral ischemia 1 d group，the cerebral ischemia 3 d group and the cerebral ischemia 7 d group increased，while the relative expression of Sirt1 and NRF2 protein decreased，the differences were statistically significant (P＜0.05).Compared with the cerebral ischemia 1 d group，the relative expression of miR-34a mRNA in the cerebral ischemia 3 d group and the cerebral ischemia 7 d group increased，and the relative expression of Sirt1 and NRF2 protein decreased，the differences were statistically significant (P＜0.05).Compared with the cerebral ischemia 3 d group，the relative expression of miR-34a mRNA in the cerebral ischemia 7 d group increased，while the relative expression of Sirt1 and NRF2 protein decreased，and the differences were statistically significant(P＜0.05).Conclusion miR-34a may regulate the proliferation of endogenous neural stem cells after cerebral ischemic injury by regulating Sirt1/NRF2 pathway.
		2020 Vol. 27 (33): 29-31转35 [Abstract] ( 20 ) HTML (34 KB) PDF (0 KB) ( 10 )

	32	Analysis on the clinicopathological features of small cell neuroendocrine carcinoma of the cervix
		LIU Bing-ying；LIU Yu-hong；LI Xiao-ming
		Objective To investigate the clinicopathological and immunohistochemical features of small cell neuroendocrine carcinoma of the cervix （SCCC）.Methods A total of 5 cases of SCCC patients were collected and studied by light microscope and immunohistochemistry from May 2006 to March 2020 in Bao′an District People′s Hospital in Shenzhen City.Results The histology of 5 cases showed that the tumor cells were small and round or sunflower-like，the cytoplasm was sparse，the nucleolus was not easy to be seen，and the tumor cells grew in mosaic-like nests.Immunohistochemistry showed that 5 cases expressed at least 2 kinds of neuroendocrine markers(Syn，CGA and CD56)，2 cases diffusely expressed TTF-1，5 cases of CD117 were negative.Conclusion SCCC has unique clinicopathologic and immunohistochemical features，and immunohistochemistry plays an important role in the diagnosis and differential diagnosis.SCCC specifically expresses more than one neuroendocrine marker，TTF-1 has no significance in the differential diagnosis of cervical metastasis between primary SCCC and non-small cell carcinoma，CD117 has some significance in the differential diagnosis of both.
		2020 Vol. 27 (33): 32-35 [Abstract] ( 23 ) HTML (37 KB) PDF (0 KB) ( 14 )

	36	Application effect of asthma in the whole process management of moderate bronchial asthma attack housekeeper shubao
		MA Zhan-cheng
		Objective To investigate the application of asthma housekeeper shubao in the whole process management of moderate bronchial asthma attact.Methods A total of eighty-six patients with moderate bronchial asthma admitted to Hexian Memorial Hospital of Panyu District in Guangzhou City from April 2017 to January 2018 were selected as the research objects.They were divided into control group (n=43) and observation group (n=43) according to random number table method.The control group used the conventional management method，and the observation group was managed on the basis of the control group in conjunction with the asthma butler.Pulmonary function levels，asthma control test (ACT) scores，and management quality were compared between the two groups.Results The forced expiratory volume in the first second (FEV1)，FEV1 as a prjected percentaye (FEV1%) and peak expiratory flow (PEF) levels of the observation group were higher than those in the control group after 6 months′ management，the differences were statistically significant （P＜0.05）.The daily activities，dyspnea，asthma symptoms，first aid medication，and asthma control scores of the observation group were higher than those of the control group after 6 months′ management，the differences were statistically significant （P＜0.05）.The management content，management method，management form，management approach and service attitude scores of the observation group were higher than those of the control group after 6 months′ management，and the differences were statistically significant （P ＜0.05）.Conclusion Asthma housekeeper Shubao can improve the pulmonary function level and ACT score of patients with moderate bronchial asthma attack treatment，which can improve the management quality and is worthy of promotion and application.
		2020 Vol. 27 (33): 36-39 [Abstract] ( 19 ) HTML (35 KB) PDF (0 KB) ( 12 )

	40	Application of Pinaverium Bromide combined with Scopolamine Butylbromide in endoscopic retrograde cholangiopancreatography
		WANG-Jian；CHEN Wei-feng；LIU Yuan-dong
		Objective To analyze the application effect of Pinaveonium Bromide combined with Scopolamine butylbromide in endoscopic retrograde cholangiopancreatography (ERCP).Methods Seventy-five patients who underwent endoscopic retrograde cholangiopancreatography in the Department of Gastroenterology，Guangxin District People′s Hospital，Shangrao City，Jiangxi Province from January 2018 to February 2020 were selected.According to odd and even grouping method，they were divided into control group (n=37) and observation group (n=38).The control group used 30 minutes before surgery: Pethidine and Diazepam;the observation group used Pethidine and Diazepam routinely on the basis of pan medication，Pinaverium Bromide combined with Scopolamine Butylbromide to compare the successful intubation time of patients of the two groups，monitor and compare the serum amylase content at 3h and 24h after operation;compare the incidence of complications and abdominal pain in patients.Results The time of successful intubation in the observation group was (3.71±0.63) min，shorter than that in the control group of (5.48±0.72) min.The serum amylase level was lower than that in the control group at 3h and 24h after surgery，and the degree of abdominal pain was lower than that in the control group，with statistically significant differences (P＜0.05).The total incidence of postoperative complications was 2.63% in the observation group and 16.22% in the control group，with statistically significant difference (P＜0.05).Conclusion Pinaverium Bromide combined with Scopolamine Butylbromide can shorten the intubation time of patients with endoscopic retrograde cholangiopancreatography，reduce the incidence of complications，and reduce abdominal pain significantly，which is worth popularizing.
		2020 Vol. 27 (33): 40-42转46 [Abstract] ( 26 ) HTML (36 KB) PDF (0 KB) ( 9 )

	43	Effect of Glutathione combined with Alprostadil treating acute kidney injury in sepsis
		LUO Ju-hui；XU-Zhong；LONG Xin-cong；LONG Yong-jian；HU Hui-lian
		Objective To explore the effect of Glutathione combined with Alprostadil treating acute kidney injury in sepsis.Methods The clinical data of 80 patients with acute kidney injury in sepsis admitted to the Department of Intensive Medicine of the Second People′s Hospital of Baiyun District，Guangzhou from January 2017 to June 2019 were analyzed retrospectively.According to the different drug treatment methods，they were divided into the combined group and the control group，40 cases in each group.The control group received routine intravenous drip of Alprostadil，10 μg/time，qd;the combined group received glutathione treatment on the basis of the control group，0.6 g/time，qd，both groups were treated for 10 days.The curative effect at 10 days after treatment and the changes in serum tissue plasminogen activator (TPA) and plasminogen activator inhibitor (PAI-1) levels of the two groups were observed;the acute physiology and chronic health scores (APACHE Ⅱ)，systemic infection-related organ failure score (SOFA) were used to assess the changes in patients′ condition.Results The total effective rate of the combined group was higher than that of the control group，the difference was statistically significant difference (P＜0.05);the serum TPA and PAI-1 levels of the combined group were lower than those of the control group，there were statistically significant differences(P＜0.05);the APACHEⅡand SOFA scores of the combined group were lower than those of the control group，the differences were statistically significant (P＜0.05).Conclusion Glutathione combined with Alprostadil can improve the therapeutic effect and reduce the levels of TPA and PAI-1 in patients with acute kidney injury in sepsis.
		2020 Vol. 27 (33): 43-46 [Abstract] ( 25 ) HTML (36 KB) PDF (0 KB) ( 9 )

	47	Clinical effect of Esomeprazole in the treatment of peptic ulcer with acute upper gastrointestinal hemorrhage
		HUANG Xiao-jing；LUO Li-yuan；ZHONG Hua-wen
		Objective To observe the clinical effect of Esomeprazole in the treatment of peptic ulcer with acute upper gastrointestinal hemorrhage.Methods From June 2018 to December 2019，a total of 120 patients with peptic ulcer and acute upper gastrointestinal hemorrhage treated in Yangjiang Traditional Chinese Medicine Hospital were selected as the research objects.According to the random number table wethod，they were divided into observation group (60 cases)and control group (60 cases).The control group was treated with Omeprazole and the observation group was treated with Esomeprazole.The pH value of fasting gastric juice before and after treatment，the disappearance time of clinical symptoms and the total effective rate of the two groups were compared.Results There was no statistically significant difference in fasting gastric juice pH value between the two groups before treatment （P＞0.05），and fasting gastric juice pH value of the observation group was higher than that of the control group after treatment，the difference was statistically significant （P＜0.05）;the time of hemostasis，stopping hematemesis and turning yellow stool in the observation group was shorter than that in the control group，the differences were statistically significant （P＜0.05）;the total effective rate of the observation group was 95.0%，which was higher than 75.0% of the control group，the difference was statistically significant（P＜0.05）.Conclusion Esomeprazole can improve the clinical symptoms and increase the pH value of gastric juice of patients with peptic ulcer and acute upper gastrointestinal hemorrhage，the effect is reliable and can be popularized.
		2020 Vol. 27 (33): 47-49 [Abstract] ( 23 ) HTML (33 KB) PDF (0 KB) ( 13 )

	50	Review and effect evaluation of pharmacists′intervention on outpatient and emergency antibiotic prescriptions
		YAN Fei；WANG Jing-yan；LE Liang
		Objective To evaluate the intervention effect of outpatient and emergency antimicrobial prescription comments，therefore to promote rational use of antibacterials.Methods With the help of the clinical pharmacy management system (PASS)，a total of 809 outpatient and emergency antimicrobial prescriptions from Jingdezhen First People′s Hospital were randomly selected from January to December in 2018 as the pre-intervention group，while a total of 871 outpatient and emergency antimicrobial prescriptions from Jingdezhen First People′s Hospital were randomly selected from January to December in 2019 as the post-intervention group，and then for prescription comment analysis.Results After intervention，the qualified rate of outpatient and emergency antibiotics prescription increased from 78.49% to 89.90%，the difference was statistically significant （P＜0.05）;the major problems，such as the use of antibiotics without indication，inappropriate selection of drugs，and the irrationality rate of drugs not conforming to hierarchical management were lower than those of the pre-intervention group，the differences were statistically significant （P＜0.05）;before and after the intervention，antibiotics were mainly used by oral administration and single use.Conclusion Pharmacist intervention can effectively improve the quality of outpatient and emergency antimicrobial prescription，and to promote rational drug use.
		2020 Vol. 27 (33): 50-52 [Abstract] ( 21 ) HTML (33 KB) PDF (0 KB) ( 9 )

	53	Clinical study of combination of Anlotinib and Tegafur in the third line treatment of advanced lung squamous cell carcinoma
		HUA Xiao-mei
		Objective To investigate the clinical value of Anlotinib combined with S-1 in the treatment of advanced lung squamous cell carcinoma.Methods A total of 60 patients who were diagnosed with lung squamous cell carcinoma stage Ⅳand had progressed through second-line treatment were selected in Pingkuang General Hospital，Pingxiang City，Jiangxi Province from September 2018 to September 2019.They were divided into treatment group，control group 1 and control group 2 according to the random number table method，20 cases in each group.The treatment group was treated with Anlotinib + Tiggio，the control group 1 was treated with Anlotinib + placebo，and the control group 2 was treated with Tiggio + placebo.The treatment effect and adverse reactions of the three groups were compared.Results The progression free survival (PFS) of the treatment group was longer than that of the control group 1 and 2，the difference was statistically significant (P＜0.05);comparison the objective remission rate (ORR) of the three groups，the difference was not statistically significant (P＞0.05).The disease control rate (DCR) of the treatment group was higher than that of the control group 1 and 2，and the overall survival time (OS) was longer than that of the control group 1 and 2，there were significant differences （P＜0.05）.There was no significant difference in the total incidence of adverse reactions among the three groups (P＞0.05).Conclusion The combination of Anlotinib and Tegafur treatment can effectively control the development of patients′ condition，prolong the survival time of patients，and does not increase serious adverse reactions，which is worthy of promotion.
		2020 Vol. 27 (33): 53-55 [Abstract] ( 26 ) HTML (33 KB) PDF (0 KB) ( 12 )

	56	Curative effect of closed reduction and intramedullary nail internal fixation in elderly patients with humeral shaft fracture
		SUN Yue-xian；LIU Bo-qiang；MENG Wei；YU Jing
		Objective To investigate the curative effect of closed reduction and intramedullary nail internal fixation in elderly patients with humeral shaft fracture.Methods A total of 80 elderly patients with humeral shaft fracture admitted to Mudanjiang Forestry Central Hospital from September 2018 to August 2019 were selected as the study subjects.The patients were divided into the open group (40 cases) and the closed group (40 cases) according to the random number table method.In the open group，open reduction and internal fixation with plate and screw were performed.In the closed group，closed reduction and internal fixation with intramedullary nail were performed.Intraoperative blood loss，operative time，hospital stay，humeral shaft fracture healing time，elbow joint functional recovery and complication rate were compared between the two groups.Results The intraoperative blood loss of patients in the closed group was less than that in the open group，the operative time and hospital stay were shorter than those in the open group，the excellent and good rate of elbow joint function score was higher than that in the open group，and the total incidence of complications was lower than that in the open group，and the differences were statistically significant (P＜0.05).There was no significant difference in fracture healing time between the two groups (P＞0.05).Conclusion Closed reduction and internal fixation with intramedullary nail can effectively improve the treatment of humeral shaft fracture in the elderly.
		2020 Vol. 27 (33): 56-58转65 [Abstract] ( 23 ) HTML (34 KB) PDF (0 KB) ( 7 )

	59	Value analysis of red blood cell distribution width in the evaluation of the prognosis of percutaneous coronary intervention in patients with acute myocardial infarction
		ZHOU Le-qin；HE Wei-xi；XU Hui-lin；WANG Ping；LIU Zhi-jian
		Objective To investigate the value of red blood cell distribution width (RDW) in evaluation of the prognosis of percutaneous coronary intervention (PCI) in patients with acute myocardial infarction.Methods A total of 100 acute myocardial infarction patients with PCI who were admitted to the First People′s Hospital of Jingdezhen City from January 2017 to January 2019 were selected as the research objects.According to the RDW level of blood routine，the optimal threshold was determined as 12.7% based on the receiver operating characteristic curve.The patients were divided into group A(58 cases，RDW＜12.7%)and group B(42 cases，RDW≥12.7%)according to RDW value.They were given postoperative 1 year of follow-up.The left ventricular end-diastolic volume index (EDVI)，left ventricular end-systolic volume index (ESVI)，wall motion score index (WMSI) and the incidence of adverse reactions were compared at different time between the two groups.Results There were no statistically significant differences in the EDVI，ESVI and WMSI between the two groups within 2 d of onset (P＞0.05).After surgery for 1，6 and 12 months，the EDVI，ESVI and WMSI in two groups were lower than those within 2 d of onset，and the differences were statistically significant (P＜0.05).After surgery for 1，6 and 12 months，the EDVI，ESVI and WMSI in group A were lower than those in group B，and the differences were statistically significant (P＜0.05).The total incidence of adverse reactions in group A (5.17%) was lower than that in group B (21.42%)，and the difference was statistically significant (P＜0.05).Conclusion Patients with acute myocardial infarction with RDW＜12.7% have better cardiac function recovery within 1 year after PCI than those with RDW≥12.7%.In addition，the total incidence of adverse reactions is lower and the prognosis is better，which can be used as a reference for clinical judgment of the prognosis of patients with acute myocardial infarction.
		2020 Vol. 27 (33): 59-61转69 [Abstract] ( 21 ) HTML (32 KB) PDF (0 KB) ( 7 )

	62	Effect of Milrinone combined with Trimetazidine on hemodynamics and heart rate variability in patients with congestive heart failure
		YAN Bo-yu；LIU Ting；DU Qian；PAN Li-hua
		Objective To investigate the effect of Milrinone combined with Trimetazidine on hemodynamics and heart rate variability in patients with congestive heart failure (CHF).Methods A total of 100 patients with CHF who were admitted to People′s Hospital of Pingxiang City in Jiangxi Province from October 2017 to October 2019 were selected as the research objects and divided into two groups according to random number table method，with 50 cases in each group.The control group was treated with oral Trimetazidine，and the observation group was treated with Milrinone on the basis of the control group，with 1 week of treatment in two groups.The curative effect，cardiac function (left ventricular end systolic diameter[LVESD]，left ventricular end diastolic diameter[LVEDD]，interventricular septal thickness[IVST]，left ventricular posterior wall thickness [LVPWT]，N-terminal pro-brain natriuretic peptide [NT-proBNP])，hemodynamics (cardiac index [CI]，cardiac output [CO])，heart rate variability (standard deviation of normal to normal intervals [SDNN]，standard deviation of per 5 min averages normal number of intervals [SDANN]，24 h adjacent R-R interval difference＞50 ms percentage [PNN50]，low frequency [LF]，high frequency [HF]，LF/HF) and the adverse reactions were compared between the two groups.Results The total clinical effective rate of the observation group was higher than that of the control group，and the difference was statistically significant (P ＜0.05).The levels of LVESD，LVEDD，IVST，LVPWT and NT-proBNP in the observation group were lower than those in control group，the levels of CI，CO，SDNN，SDANN，PNN50，LF，HF，LF/HF in the observation group were higher than those in the control group，and the differences were statistically significant (P＜0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups (P＞0.05).Conclusion Milrinone combined with Trimetazidine in the treatment of patients with CHF can improve hemodynamics and heart rate variability indexes，protect car diac function and have higher safety，which provides theoretical basis and new ideas for clinical promotion and application.
		2020 Vol. 27 (33): 62-65 [Abstract] ( 22 ) HTML (36 KB) PDF (0 KB) ( 11 )

	66	Effect of Clopidogrel combined with Aspirin on exercise endurance and inflammatory indexes in patients with acute myocardial infarction and heart failure
		LI Kai-qiao
		Objective To investigate the effect of Clopidogrel combined with Aspirin on exercise tolerance and inflammation indexes in patients with acute myocardial infarction and heart failure.Methods A total of 82 patients with acute myocardial infarction and heart failure who were treated in Qixia District Hospital of Nanjing City from January 2016 to August 2019 were selected as the research objects.They were divided into the control group and the observation group according to random number table method，with 41 cases in each group.The control group was treated with Aspirin alone，and the observation group was treated with Clopidogrel on the basis of the control group.Two groups were both treated for 3 months.The clinical efficacy，exercise endurance and inflammation indexes at 1 and 3 months of treatment were compared between the two groups.Results The total effective rate of clinical treatment in the observation group (95.12%) was higher than that in the control group (78.05%)，and the difference was statistically significant (P＜0.05).There were no statistically significant differences in continuous exercise time (ED) and peak oxygen consumption (VO2peak) and anaerobic metabolism threshold (AT) levels between the two groups at 1 months of treatment (P＞0.05).At 3 months of treatment，the ED，VO2peak and AT of the two groups were higher than those at 1 months of treatment，and the differences were statistically significant (P＜0.05).At 3 months of treatment，the ED，VO2peak and AT of the observation group were higher than those of the control group，and the differences were statistically significant (P＜0.05).There were no statistically significant differences in serum interleukin-6 (IL-6)，tumors necrosis factor-α (TNF-α) and C-reactive protein (CRP) between the two groups before treatment (P＞0.05).At 3 months of treatment，the IL-6，TNF-α and CRP of the two groups were lower than those before treatment，and the differences were statistically significant (P＜0.05).At 3 months of treatment，the IL-6，TNF-α and CRP of the observation group were lower than those of the control group，and the differences were statistically significant (P＜0.05).Conclusion The combined treatment of Clopidogrel and Aspirin can reduce the level of inflammatory indexes in patients with acute myocardial infarction and heart failure，further improve exercise endurance and improve the therapeutic effect.
		2020 Vol. 27 (33): 66-69 [Abstract] ( 22 ) HTML (35 KB) PDF (0 KB) ( 8 )

	70	Clinical application effect comparison of Rosuvastatin and Atorvastatin in the treatment of coronary heart disease
		LIU Jia-ni
		Objective To compare the clinical effect of Rosuvastatin and Atorvastatin in the treatment of coronary heart disease.Methods A total of 500 patients with coronary heart disease who admitted to the Second Affiliated Hospital of Shenyang Medical College from April 2018 to April 2019 were selected as the research objects and randomly divided into the experimental group and the control group by dynamics，with 250 cases in each group.The experimental group was treated with Rosuvastatin and the control group was treated with Atorvastatin.The clinical efficacy，cardiac function indexes，blood lipid levels and adverse reactions were compared between the two groups of patients.Results The total effective rate of the experimental group (96.00%) was higher than that of the control group (70.00%)，and the difference was statistically significant (P＜0.05).After treatment，the left ventricular ejection fraction (LVEF) of the two groups was higher than that before treatment，the left ventricular end diastolic diameter (LVEDD) of the two groups was lower than that before treatment，and the differences were statistically significant (P＜0.05).After treatment，the LVEF of the experimental group was higher than that of the control group，the LVEDD of the experimental group was lower than that of the control group，and the differences were statistically significant (P＜0.05).After treatment，the triglyceride，total cholesterol，and low-density lipoprotein of the two groups were lower than those before treatment，high-density lipoprotein contents of the two groups were higher than those before treatment，and the differences were statistically significant (P＜0.05).After treatment，triglyceride，total cholesterol，low-density lipoprotein of the experimental group were lower than those of the control group，high-density lipoprotein of the experimental group was higher than that of the control group，and the differences were statistically significant (P＜0.05).The total incidence of adverse reactions in experimental group (4.80%) was lower than that in the control group (12.80%)，and the difference was statistically significant (P＜0.05).Conclusion Rosuvastatin in the treatment of patients with coronary heart disease can improve the clinical efficacy，effectively improve blood lipid indexes and cardiac function indexes，and the drug is safer，so it is worthy of clinical promotion and application.
		2020 Vol. 27 (33): 70-72 [Abstract] ( 24 ) HTML (32 KB) PDF (0 KB) ( 10 )

	73	Clinical study of Yuquan Pills in the treatment of schizophrenia with metabolic syndrome
		PAN Xiao-wen
		Objective To explore the influence of Yuquan Pills on blood glucose，blood lipid and blood pressure in schizophrenic patients with metabolic syndrome.Methods A total of 80 schizophrenic patients with metabolic syndrome from June to December 2019 in Nanchang 334th Hospital were selected and divided into the control group and the observation group according to the random number table method，40 cases in each group.Both groups maintained the original antipsychotic treatment，the observation group was given Yuquan Pills treatment，the control group was given equal dose placebo.The levels of blood glucose，blood lipid，body mass index (BMI) and blood pressure were compared between the two groups.Results There were no significant differences in the levels of fasting blood glucose (FBG)，2-hour postprandial blood glucose (2 h PG)，triglyceride (TG)，high-density lipoprotein (HDL)，BMI，diastolic blood pressure and systolic blood pressure between the two groups before treatment (P＞0.05).After treatment，the levels of FPG([5.04±0.89]mmol/L)，2 h PG ([6.63±1.05]mmol/L) in the observation group were lower than those in the control group([7.23±1.05]mmol/L，[9.48±1.63]mmol/L)，and the differences were statistically significant (P＜0.05).The levels of TG([1.24±0.21]mmol/L) and BMI ([23.55±2.86]kg/m2) in the observation group after treatmrnt were lower than those in the control group ([1.93±0.34]mmol/L，[26.74±3.12]kg/m2)，and the level of HDL ([1.34±0.23]mmol/L) in the observation group after treatment was higher than that in the control group ([0.96±0.15]mmol/L)，and the differences were statistically significant (P＜0.05).The levels of diastolic blood pressure ([80.14±4.29]mmHg) and systolic blood pressure([121.45±7.05]mmHg) in the observation group after treatment were lower than those in the control group ([86.74±5.12]mmHg，[128.45±7.53]mmHg)，the differences were statistically significant (P＜0.05).Conclusion Yuquan Pills can reduce the blood pressure level of schizophrenia patients with metabolic syndrome，improve the metabolism of glucose and lipid，reduce the body weight and promote the improvement of the disease.
		2020 Vol. 27 (33): 73-75转79 [Abstract] ( 25 ) HTML (33 KB) PDF (0 KB) ( 10 )

	76	Analysis of related influence factors of collateral circulation establishment in patients with ischemic cerebrovascular disease and its relationship with the degree of neurological impairment
		GAO Xiu-xian
		Objective To investigate the related influencing factors of collateral circulation establishment in patients with ischemic cerebrovascular disease and its relationship with the degree of neurological impairment.Methods The clinical data of 148 patients with ischemic cerebrovascular disease admitted to Jiujiang First People′s Hospital from October 2017 to May 2020 were retrospectively analyzed.According to the collateral circulation establishment by digital subtraction angiography (DSA)，the patients were divided into the collateral circulation establishment group (87 cases)and the collateral circulation non-establishment group (61 cases).The related influence factors of the establishment of collateral circulation in patients with ischemic cerebrovascular disease and the relationship with the degree of neurological impairment were analyzed.Results The proportions of National Institutes of Health Stroke Scale (NIHSS) score ≤3 and infarct diameter ≤15 mm in the collateral circulation establishment group were higher than those in the collateral circulation non-establishment group，the differences were statistically significant (P＜0.05).Logistic regression analysis showed that hypertension，smoking history，diabetes and homocysteine ≥15 μmol/L were the high risk influence factors of the establishment of collateral circulation in patients with ischemic cerebrovascular disease (P＜0.05 and OR≥1).Conclusion The establishment of collateral circulation can reduce the infarct volume and the degree of nerve injury in patients with ischemic cerebrovascular disease，and the establishment of collateral circulation in patients with ischemic cerebrovascular disease is affected by many factors.It is necessary to strengthen the prevention and treatment of risk factors in order to improve the prognosis of patients.
		2020 Vol. 27 (33): 76-79 [Abstract] ( 23 ) HTML (31 KB) PDF (0 KB) ( 7 )

	80	Clinical effect of Aspirin combined with Clopidogrel in the treatment of cerebral infarction
		WU Xi
		Objective To study the clinical effect of Aspirin combined with Clopidogrel in the treatment of cerebral infarction.Methods A total of 100 patients with cerebral infarction in Iron and Coal General Hospital of Liaoning Health Industry Group from January 2018 to December 2019 were selected，and divided into the control group and the observation group according to random number table method，50 patients in each group.The control group was treated with Aspirin，the observation group was treated with Aspirin and Clopidogrel.The neurological deficit score，daily living ability，cognitive ability，and the total treatment effectiveness were compared between the two groups.Results The total treatment efficiency of the observation group was 92%，which was higher than 72% of the control group，the difference was statistically significant (P＜0.05).The neurological deficit score of the observation group after treatment was lower than that of the control group，the difference was statistically significant (P＜0.05).The cognitive function score of the observation group after treatment was higher than that of the control group，the difference was statistically significant(P＜0.05).The score of daily life ability in the observation group after treatment was higher than that in the control group，the difference was statistically significant (P＜0.05).Conclusion Aspirin combined with Clopidogrel in the treatment of patients with cerebral infarction can effectively improve the total effective rate，improve the cognitive ability，neurological function and daily living ability of patients，which has important clinical research value.
		2020 Vol. 27 (33): 80-82 [Abstract] ( 23 ) HTML (31 KB) PDF (0 KB) ( 8 )

	83	Influence of day case surgery mode on postoperative discomfort and gastrointestinal function of adult patients with hernia operation
		YU Li-he；ZOU Fei；YI Wei；WANG Zhi-ling；HU Zhao-ping
		Objective To investigate the influence of day case surgery mode on postoperative discomfort and gastrointestinal function of adult patients with hernia operation.Methods A total of 60 adult patients with hernia operation in the First Hospital of Nanchang City of Jiangxi Province from January 2017 to March 2019 were selected as the research objects and divided into the control group(underwent inpatients surgical treatment)and the observation group(underwent day case surgical treatment) according to the odd-even method，with 30 cases in each group.The operation time，intraoperative blood loss，hospitalization time，total incidence of complications，postoperative discomfort degree and gastrointestinal hormone levels at different time before and after the operation of two groups were compared.Results There were no statistically significant differences in the operation time and intraoperative blood loss of two groups (P＞0.05).The hospitalization time of the observation group was shorter than that of the control group，the total incidence of complications was lower than that of the control group，the postoperative discomfort degree was lower than that of the control group，and the differences were statistically significant (P＜0.05).There were no statistically significant differences in the gastrointestinal hormone levels before operation of two groups(P＞0.05).The gastrointestinal hormone levels of the observation group after operation were higher than those of the control group，and the differences were statistically significant (P＜0.05).Conclusion The effect of day case surgery mode for postoperative discomfort of adult patients with hernia operation is better，and its bad influence on gastrointestinal function is smaller，so its application value in these patients is relatively higher.
		2020 Vol. 27 (33): 83-86 [Abstract] ( 23 ) HTML (36 KB) PDF (0 KB) ( 8 )

	87	Clinical effect of non-surgical treatment of postoperative anastomotic leakage of Grade B and C in patients with rectal cancer
		CHEN Jin-qiang；ZHANG Xiao-wei；HONG Bo；DING Jin-huo；ZHANG Jun-ming
		Objective To explore the clinical effect of non-surgical treatment for patients with anastomotic fistula B and C after rectal cancer surgery.Methods A total of 20 patients with anastomotic fistula B and C after rectal cancer surgery in Shangrao People′s Hospital from March 2018 to August 2019，all received non-surgical treatment，and treated them as the observation group.A total of 20 cases of rectal cancer were randomly selected，the patients who had anastomotic fistula B and C after surgery were treated as the control group from March 2017 to August 2018.The length of hospitalization，hospitalization expenses and quality of life scores were compared between two groups.Results The length of hospitalization of the observation group was shorter than that in the control group，hospitalization expense of the observation group was less than that of the control group，the differences were statistically significant (P＜0.05).After treatment，the quality of life score of the observation group was higher than that of the control group，and the difference was statistically significant (P＜0.05).Conclusion When non-surgical treatment is performed for anastomotic grade B and C fistulas after rectal cancer，the patient recovers quickly，the economic pressure is small，and the patient′s quality of life improves significantly，which is worthy of promotion.
		2020 Vol. 27 (33): 87-89 [Abstract] ( 24 ) HTML (29 KB) PDF (0 KB) ( 7 )

	90	Effect comparison of the laparoscopic and laparotomic total mesorectal excision with pelvic autonomic nerve-preserving in the treatment of rectal cancer
		XIA Lv-chi；WAN Yan-hua；WANG Chuan-wen
		Objective To compare the clinical effect of laparoscopic and laparotomic total mesorectal excision (TME)with pelvic autonomic nerve-preserving (PANP) in the treatment of rectal cancer.Methods A total of seventy-six patients with rectal cancer who were treated in the First People′s Hospital of Jiujiang City，Jiangxi Province from November 2016 to December 2018 were selected as the research objects and divided into the observation group and the control group according to the random number table method，with 38 cases in each group.Patients in the observation group received TME treatment with PANP under laparoscope，and patients in the control group received TME treatment with PANP under open surgery.The perioperative indicators，voiding function，the total incidence of sexual dysfunction and prognosis condition were compared between the two groups.Results The intraoperative blood loss ([103.57±22.06]mL)and the residual urine volume ([15.23±4.97]mL) of the observation group were lower than those of the control group([178.79±32.64]，[22.51±6.14]mL)，and the differences were statistically significant (P＜0.05).The operation time of the observation group ([175.34±42.18]min) was longer than that of the control group ([138.52±36.27]min)，and the difference was statistically significant (P＜0.05).The time of exhaust ([2.64±1.20]d)，hospital stay ([6.17±1.25]d)，and time of catheter removal ([2.54±1.38]d) in the observation group were shorter than those in the control group ([3.59±1.42]，[11.21±2.03]，[3.36±1.42]d)，and the differences were statistically significant (P＜0.05).The free urine flow rate ([26.97±5.28]mL/s) of the observation group was higher than that of the control group ([20.63±6.24]mL/s)，and the difference was statistically significant (P＜0.05).The incidence of ejaculation disorder and erectile dysfunction in the observation group (10.53%，5.79%) were lower than those in the control group (34.21%，36.84%)，and the differences were statistically significant (P＜0.05).There were no statistically significant differences in amount of lymph node dissection，incidence of urination disorder，recurrence rate，and metastasis rate between the two groups (P＞0.05).Conclusion For patients with rectal cancer，laparoscopic TME treatment with PANP has little damage and a definite radical cure effect，which can shorten the hospital stay，and improve voiding and sexual function.
		2020 Vol. 27 (33): 90-93 [Abstract] ( 18 ) HTML (35 KB) PDF (0 KB) ( 8 )

	94	Effect of early rehabilitation training combined with comprehensive physical therapy on hand dysfunction after traumatic peripheral nerve injury
		YE Fang XU Hui WANG Yan-sheng YU Ning
		Guide::
		Objective To explore the effect of early rehabilitation training combined with comprehensive physical therapy on hand dysfunction after traumatic peripheral nerve injury.Methods A total of 80 patients with hand dysfunction caused by traumatic peripheral nerve injury admitted to Central Hospital Affiliated to Shenyang Medical College from January 2018 to April 2019 were selected as the research objects and divided into the control group and the observation group according to the random number table method，with 40 cases in each group.The control group received early passive surgical functional exercise，while the observation group received early functional rehabilitation training combined with physical therapy.The peak blood flow of main nutrient vessels in upper limbs，the median nerve sensory and motor nerve conduction velocity，clinical symptoms after follow-up for 1 year and the changes of hand function scores during the intervention were compared between the two groups.Results The peak blood flow of brachial artery and axillary artery in the observation group after intervention were higher than those in the control group，and differences were statistically significant (P＜0.05).The median nerve sensory and motor nerve conduction velocity in the observation group after intervention were higher than those in the control group，and differences were statistically significant (P＜0.05).The incidence rates of limb numbness，joint stiffness，chronic pain and limb atrophy in the observation group after 1 year follow-up were lower than those in the control group，and differences were statistically significant (P＜0.05).The hand function scores in the observation group at three months after intervention and one year after intervention were higher than those in the control group，and differences were statistically significant (P＜0.05).Conclusion For hand dysfunction caused by traumatic peripheral nerve injury，early rehabilitation therapy combined with comprehensive physical intervention can significantly improve blood circulation an
		2020 Vol. 27 (33): 94-97 [Abstract] ( 14 ) HTML (37 KB) PDF (0 KB) ( 7 )

	98	Effect and safety of minimally invasive puncture in the treatment of traumatic intracranial hemorrhage in children
		QIU Wen-qi1?GAO Jie2?YANG Ming1?ZHANG Jin-an1
		Guide::
		Objective To explore the effect and safety of minimally invasive puncture in the treatment of traumatic intracranial hemorrhage in children.Methods A total of 80 cases of children with traumatic intracranial hemorrhage who were treated in Jiangxi Provincial Children′s Hospital from January 2017 to December 2019 were selected as the research objects and divided into the control group and the observation group according to random number table method，with 40 cases in each group.The control group used craniotomy and the observation group used minimally invasive puncture.The clinical efficacy，clinical indicators and complications of the two groups were compared.Results The total effective rate of the observation group was higher than that of the control group，and the difference was statistically significant (P＜0.05).The operation time，awake time and hospitalization time of the observation group were shorter than those of the control group，the hematoma clearance rate was lower than that of the control group，and the differences were statistically significant (P＜0.05).The total incidence of complications of the observation group was lower than that of the control group，and the difference was statistically significant (P＜0.05).Conclusion Although the hematoma clearance rate of children with traumatic intracranial hemorrhage who are treated by minimally invasive puncture is lower，but it has relatively simple operation and small trauma，and it is conducive to postoperative recovery and has high safety.
		2020 Vol. 27 (33): 98-100 [Abstract] ( 14 ) HTML (35 KB) PDF (0 KB) ( 7 )

	101	Influence of gymnastic exercises during pregnancy on maternal and neonatal outcomes of primiparas
		TAN Cai1?REN Yu-zhi2▲
		Guide::
		Objective To explore the impact of gymnastic exercises during pregnancy on maternal and neonatal outcomes for primiparas，and provide evidence for instructing pregnant women performing gymnastic exercises.Methods From October 1 to December 31，2017，a total of 136 health primiparas performed routine labor tests in the Jiangxi Maternal and Child Health Hospital，who volunteered to participate in this study as the research subjects，and they were divided into a study group (n=68) and a control group (n=68) according to the random number table method.The control group received routine physical examination and health education without systematic exercise，the study group was intervened by a specific gymnastics exercise on the basis of control group.Face-to-face interview and phone interview were carried out to collect related information at the beginning of the study and the participants gave birth one week later.Results A total of 124 primiparas completed the study，68 primiparas in the control group and 56 primiparas in the study group.Pregnancy weight gain in the study group was less than that in the control group，and the incidence of complications in the study group was lower than that in the control group，the rates of breastfeeding and natural delivery in the study group were higher than those in the control group，the differences were statistically significant(P＜0.05).There were no significant differences between the two groups in terms of premature and neonatal weight (P＞0.05).The first and second birth process time of primiparas in the study group who were natural delivery (n=44) was shorter than that in the control group (n=40)，the difference was statistically significant (P＜0.05).There was no significant difference in the incidence of postpartum hemorrhage between the two groups of primiparas gave birth naturally(P＞0.05).Conclusion The results of this study showed that insist performing gymnastic exercises during pregnancy can improve maternal and neonatal health outcomes.These findings can be important for medical staff to instruct pregnant women performing gymnastic exercises regularly during pregnancy.
		2020 Vol. 27 (33): 101-104 [Abstract] ( 11 ) HTML (34 KB) PDF (0 KB) ( 6 )

	105	Effect of different cervical ripening regimens on maternal-infant outcomes and postoperative recovery in patients with gestational diabetes mellitus of full-term pregnancy
		WU Dan-dan
		Guide::
		Objective To explore the effect of different cervical ripening regimens on maternal-infant outcomes and postoperative recovery in patients with gestational diabetes mellitus(GDM)of full-term pregnancy.Methods Retrospective analysis was performed on clinical data of 150 GDM patients from January 2016 to June 2018 in Dalian Maternal and Child Health Hospital，and the patients were divided into three groups according to the treatment methods，including single balloon group，double balloon group and Oxytocin group，50 cases in each group.Single balloon group was given Foly catheter，double balloon group was given COOK balloon，and Oxytocin group was given Oxytocin.The clinical efficacy of cervical ripening and maternal-infant outcomes were compared among the three groups，and the recovery was evaluated by recording the postoperative adverse reactions.Results After treatment，the total effective rate of cervical maturation in double balloon group (96.00%) was higher than that in single balloon group (84.00%) and Oxytocin group(66.00%)，that in single balloon group was higher than that of Oxytocin group，with statistical significances(P＜0.05).The cesarean section rate of single balloon group (10.00%) was lower than that of double balloon group(26.00%)，and that of double balloon group (26.00%) was lower than that of Oxytocin group (46.00%)，with statistical differences (P＜0.05).There was no significant difference in other maternal-infant outcomes incidence rate (postpartum hemorrhage，intrauterine infection，fetal distress and neonatal asphyxia) among the three groups (P＞0.05).The total incidence of adverse reactions in single balloon group (4.00%) was not significantly different from that in double balloon group (6.00%) (P＞0.05).The total incidence of adverse reactions in single balloon group and double balloon group was lower than that of the Oxytocin group (20.00%)，and the differences were statistically significant (P＜0.05).Conclusion Cervical dilation balloon technique is more conducive to postoperative recovery of GDM patients with fullterm pregnancy，and single dilation balloon is more conducive to natural delivery，and double-balloon group has a better effect of cervical ripening.
		2020 Vol. 27 (33): 105-107 [Abstract] ( 12 ) HTML (33 KB) PDF (0 KB) ( 7 )

	108	Clinical effect of laparoscopic hysterectomy in the treatment of middleaged and elderly patients with uterine fibroids
		SIMA Qin
		Guide::
		Objective To explore the clinical effect of the laparoscope in the treatment of the middle-aged and elderly patients with uterine fibroids.Methods From August 2017 to August 2019，100 uterine fibroids patients in Changzhou Jintan District Hospital of Traditional Chinese Medicine were collected as research objects，the patients were divided into laparoscopic group (50 cases) and laparotomy group (50 cases) by random number table method，patients in the laparoscopic group were treated with laparoscopic hysterectomy，while those in the laparotomy group were treated with transabdominal hysterectomy.The clinical therapeutic effect，intraoperative，postoperative indicators and the total incidence of postoperative complications of the two groups were compared，and the serum levels of C3 and IgG before and after surgery were tested.Results The intraoperative blood loss of the laparoscopic group was less than that of the laparotomy group，the operation time，hospital stay and anal exhaust time were shorter than those of the laparotomy group，with statistically significant differences (P＜0.05).Before operation，compared with the levels of the C3 and IgG，the differences were not statistically significant (P＞0.05).The levels of C3 and IgG after operation were lower than those before operation，the differences were statistically significant (P＜0.05).After operation，the levels of the C3 and IgG of the laparoscopic group were than those of the laparotomy group，the differences were statistically significant (P＜0.05).The total incidence of postoperative complication of the laparoscopic group was lower than that of the laparotomy group，the difference was statistically significant (P＜0.05).Conclusion Laparoscopically hysterectomy for the treatment of middleaged and elderly patients with uterine fibroids has a good clinical effect，less intraoperative bleeding and faster postoperative recovery and high safety.
		2020 Vol. 27 (33): 108-111 [Abstract] ( 14 ) HTML (1 KB) PDF (0 KB) ( 10 )

	112	Effect comparison of ectopic pregnancy treated by single port laparoscopic surgery and porous laparoscopic surgery
		HE Fang NIE Xiao-cui
		Guide::
		Objective To compare the effects of single port laparoscopic surgery and porous laparoscopic surgery for ectopic pregnancy.Methods A total of 60 ectopic pregnancy patients to Shenyang Women′s and Children′s Hospital from March 2017 to March 2018 were selected as the research objects，and divided into the observation group and the control group using random number table method，with 30 cases in each group.The observation group was treated with single port laparoscopic surgery and the control was treated with porous laparoscopic surgery.The general condition，postoperative pain，aesthetic satisfaction and complications of the two groups were compared.Results The surgery time of the observation group was longer than that of the control group，and the postoperative exhaust time and hospitalization time were shorter than those of the control group，the difference had statistically significant differences (P＜0.05);there were no statistically significant intraoperative blood loss and total cost between the two groups (P＞0.05);visual analogue scale (VAS) score of the observation group was lower than that of the control group，and aesthetic satisfaction score was higher than that of the control group，the differences were statistically significant (P＜0.05);there was no statistically significant difference in the total incidence of complications between the two groups (P＞0.05).Conclusion Single port laparoscopic surgery can reduce pain and the amount of blood loss during the operation.Patients can recover quickly after the operation，taking into account the advantages of minimally invasive and cosmetic surgery，which has a broad clinical application prospect.
		2020 Vol. 27 (33): 112-114 [Abstract] ( 12 ) HTML (31 KB) PDF (0 KB) ( 6 )

	115	Observation on the application effect of Phloroglucinol in the induction of labor in pregnancy with poor cervical conditions
		SHEN Mu-gui CHEN Li-yun LAI Juan-juan▲
		Guide::
		Objective To investigate the application effect of Phloroglucinol in the induction of labor in pregnancy with poor cervical conditions.Methods A total of 102 pregnant patients with dysfunctional cervical conditions admitted to the Department of Obstetrics and Gynecology，Putian Medical District，No.900 Hospital of Joint Logistics Support Force from December 2019 to May 2020 were selected as the research objects，and they were divided into the observation group (51 cases) and the control group (51 cases) according to random number table method.The observation group received the Phloroglucinol for treating method，and the control group received the Anisodamine for treating method.Two groups were treated for up to 3 days.The success rate of labor induction，the time from medication to the delivery of the fetus，the amount of postpartum hemorrhage，the Apgar score of the newborn 1 min after birth，the cervical maturity(Bishop) score and adverse reactions of the two groups were compared.Results The success rate of labor induction in the observation group was higher than that in the control group，the time from medication to fetus delivery was shorter than that in the control group，postpartum hemorrhage was less than that in the control group，the Apgar score of the newborn at 1 min after birth was higher than that of the control group，and the differences were statistically significant(P＜0.05).Before labor induction，there was no statistically significant difference of cervical Bishop score between the two groups (P＞0.05);12 h after the end of the medication，the Bishop scores of the two groups were higher than those before labor induction，and the observation group was higher than the control group，the differences were statistically significant (P＜0.05).The incidence of adverse reactions in the observation group was lower than that in the control group，and the difference was statistically significant (P＜0.05).Conclusion The use of Phloroglucinol to induce labor in pregnant women with poor cervical conditions has a significant effect，which can increase the effective rate of labor induction，improve cervical conditions，shorten labor，optimize delivery outcomes，and have high drug safety，which is worthy of clinical promotion.
		2020 Vol. 27 (33): 115-117 [Abstract] ( 14 ) HTML (34 KB) PDF (0 KB) ( 10 )

	118	Effect of wearing glasses on children′s development and changes of low myopia
		XIAO Hui1 XIONG Fen2 CHEN Jian1 REN Min-rong1 WU Shu-ping1
		Guide::
		Objective To investigate the influence of glasses on the development and change of children′s low myopia.Methods A total of 300 children with low myopia admitted to Yichun People′s Hospital from March 2018 to March 2019 were selected as the research objects，and the children were divided into a control group (150 cases) and an observation group (150 cases) according to the wishes of the children and their families.The control group did not undergo correction treatment and did not wear frame glasses;the observation group underwent full correction treatment according to the doctor′s instructions，and continued to wear frame glasses.The children of two groups used a comprehensive refractometer to perform refractive status and binocular visual function examination during the investigation.The abnormal rate of visual function and the rate of visual fatigue，curative effect，adjustment range，and flexibility of binocular adjustment were compared between the two groups.Results The rates of abnormal visual function and visual fatigue in the observation group were lower than those in the control group，and the differences were statistically significant (P＜0.05);the adjustment range and binocular accommodation flexibility of the observation group were higher than those in the control group，and the differences were statistically significant (P＜0.05);the effective rate of treatment of children in the observation group was higher than that in the control group，and the difference was statistically significant (P＜0.05).Conclusion Compared with those who do not wear glasses，wearing glasses for correction can better adjust the patients′ visual function.For patients with low myopia，wearing glasses for correction is recommended.
		2020 Vol. 27 (33): 118-120 [Abstract] ( 13 ) HTML (31 KB) PDF (0 KB) ( 7 )

	121	Clinical effect of different surgical approaches in the treatment of deep orbital cavernous hemangioma
		FU Rong-rong WANG Ya-wen WANG Ying-shuang
		Guide::
		Objective To explore the clinical effect of different surgical approaches in the treatment of deep orbital cavernous hemangioma，and to provide reference for the selection of surgical approaches.Methods The clinical data of 30 patients with deep orbital cavernous hemangioma who were operated in Shenyang Fourth People′s Hospital from September 2016 to November 2018 were collected retrospectively.According to the different surgical approaches，they were divided into group A (n=17)，group B (n=19)，group C (n=21) and group D (n=26).Group A，group B，group C and group D were treated by conjunctival approach，lateral approach，skin approach and lateral combined with medial conjunctival approach，respectively.The visual acuity improvement，tumor residual rate and total incidence of postoperative complications among the four groups were compared.Results There was no significant difference in the improvement of visual acuity among the four groups (P＞0.05).There was no significant difference in tumor residual rate among the four groups (P＞0.05).There was no significant difference in the total incidence of postoperative complications among the four groups (P＞0.05).Conclusion Different surgical approaches have different advantages and disadvantages in the treatment of deep orbital cavernous hemangioma.It is necessary to evaluate the development of the tumor in combination with imaging diagnosis in order to select the best approach and ensure the operation effect.
		2020 Vol. 27 (33): 121-124 [Abstract] ( 14 ) HTML (34 KB) PDF (0 KB) ( 9 )

	125	Effectiveness and safety of nasal endoscopic sinus surgery combined with low-temperature plasma turbinate radiofrequency ablation in the treatment of chronic rhinosinusitis
		ZHANG Xin-fang1 YU Yan-fang2 WANG Bao-jun3 YOU Mei1
		Guide::
		Objective To investigate the effectiveness and safety of nasal endoscopic sinus surgery combined with lowtemperature plasma turbinate radiofrequency ablation in the treatment of chronic rhinosinusitis.Methods A total of 816 patients with chronic rhinosinusitis who were treated in Bincheng Municipai Hospital of Binzhou City from April 2004 to April 2019 were selected as the research objects，and they were divided into two groups by the random number table method，namely the observation group (n=408) and the control group (n=408).The control group was treated with nasal endoscopic sinus surgery and inferior turbinoplasty (inferior turbinate osteotomy，inferior turbinate submucosal resection)，and the observation group was treated with nasal endoscopic sinus surgery and low-temperature plasma turbinate radiofrequency ablation.The treatment effect，Lund-Kennedy score，nasal resistance，sino-nasal outcome test-20(SNOT-20) score and olfactory function changes and the incidence of complications were compared between the two groups.Results The total effective rate of treatment in the observation group was 95.10%，which was higher than 75.98% in the control group，the difference was statistically significant (P＜0.05).Before treatment，there were no significant differences in nasal resistance，SNOT-20 score，Lund-Kennedy score，and olfactory function between the two groups (P ＞0.05).The nasal resistance，SNOT-20 scores，and Lund-Kennedy scores of the two groups after treatment were lower than those before treatment，and the olfactory function was better than that before treatment，the differences were statistically significant (P＜0.05).The nasal resistance，SNOT-20 scores，and Lund-Kennedy scores of the observation group after treatment were lower than those of the control group，and the olfactory function was better than that of the control group，the differences were statistically significant (P＜0.05).The total incidence rate of complications in the observation group was 4.66%，which was lower than 17.40% in the control group，the difference was statistically significant (P＜0.05).Conclusion Nasal endoscopic sinus surgery combined with low-temperature plasma turbinate radiofrequency ablation has a significant effect in the treatment of chronic rhinosinusitis，and can significantly improve the nasal ventilation and olfactory function of the patients，the safety is high，which is worthy of clinical promotion.
		2020 Vol. 27 (33): 125-128 [Abstract] ( 15 ) HTML (37 KB) PDF (0 KB) ( 9 )

	129	Effect comparison of Kangfuxin liquid on periodontal index of patients with peri-implantitis
		YU Li-fang
		Guide::
		Objective To explore the effect of Kangfuxinye on periodontal index of patients with peri-implantitis.Methods A total of 70 patients with peri-implantitis who were treated in Putian Hanjiang Hospital from March 2019 to May 2020 were selected as the research objects.They were divided into two groups by random number table，with 35 cases in each group.The control group was treated with Kangfuxin liquid washing，and the observation group was treated with Kangfuxin liquid washing + gelatin sponge plugging method，and both were treated for 4 weeks.The periodontal indexes between the two groups were compared.Results Before the intervention，there were no significant differences between the two groups in gingival crevicular bleeding index (SBI)，plaque index (PLI) and periodontal probing depth(P＞0.05);after 4 weeks of intervention，the SBI and PLI of the two groups were lower than those before intervention，and the depth of periodontal exploration was less than that before intervention，the differences were statistically significant(P＜0.05);after 4 weeks of intervention，the SBI and PLI of the observation group were lower than those of the control group，and the depth of periodontal exploration was less than that of the control group，the differences were statistically significant (P＜0.05).Conclusion Different ways of using Kangfuxin liquid have a certain influence on the treatment effect.Compared with washing methods，Kangfuxin liquid washing and gelatin sponge infiltration plugging is more effective in improving the periodontal index of patients，and it is clinically worth promoting.
		2020 Vol. 27 (33): 129-131 [Abstract] ( 13 ) HTML (33 KB) PDF (0 KB) ( 7 )

	132	Effect of peripheral nerve block anesthesia on postoperative pain and urination ways in patients with femoral fracture surgery

		Guide::
		Objective To explore the effect of peripheral nerve block anesthesia on postoperative pain and urination method in patients with femoral fracture surgery.Methods A total of 60 patients with femoral fracture surgery who were admitted to Shangrao Municipal Hospital from July 2018 to October 2019 were divided into observation group and control group according to random number table，with 30 cases in each group.The patients in control group were given routine general anesthesia，and the patients in observation group were given peripheral nerve block anesthesia.The scores of visual analogue scale (VAS) after surgery for 2，4，8，12，24 and 48 h were compared between two groups;the postoperative self-urination rate and the total incidence of adverse reactions were compared between the two groups.Results The VAS scores of observation group after surgery for 2，4，8，12，24 and 48 h were lower than those of control group，and the postoperative self-urination rate of observation group was higher than that of control group (P＜0.05).There was no statistical difference in the total incidence of adverse reactions between two groups (P＞0.05).Conclusion Peripheral nerve block anesthesia for patients with femoral fracture surgery can reduce postoperative pain and promote self-urination，whose safety is equivalent to general anesthesia，but further research is needed to verify it.
		2020 Vol. 27 (33): 132-134 [Abstract] ( 18 ) HTML (30 KB) PDF (0 KB) ( 7 )

	135	Effect of thoracic paravertebral block combined with general anesthesia on T lymphocyte subsets and tumor markers in patients undergoing lung cancer surgery
		QI Xiao-tong1 YU Yuan-bo2
		Guide::
		Objective To investigate the effect of thoracic paravertebral block combined with general anesthesia on the level of T lymphocyte subsets and tumor markers in patients with lung cancer surgery.Methods A total of 80 patients with lung cancer undergoing radical thoracoscopic surgery for lung cancer who were admitted to the Third People′s Hospital of Dalian from August 2017 to December 2019 were selected as the research objects.They were divided into an observation group (40 cases) and a control group (40 cases) according to the single blind method.The control group was operated with conventional general anesthesia，and the observation group was operated with parathoracic block combined with general anesthesia.The levels of T lymphocyte subsets and tumor markers were compared between the two groups.Results 72 hours after operation，the levels of CD3+and CD4+of T lymphocyte subsets in the observation group were higher than those in the control group，the differences were statistically significant (P＜0.05).The levels of carbohydrate antigen 199 and neuron-specific enolase in the observation group were lower than those in the control group，the differences were statistically significant (P＜0.05).Conclusion Thoracic paravertebral block combined with general anesthesia can effectively improve T lymphocyte subsets and reduce tumor markers in patients undergoing lung cancer surgery.
		2020 Vol. 27 (33): 135-137 [Abstract] ( 11 ) HTML (34 KB) PDF (0 KB) ( 8 )

	138	Comparison of the value of magnetic resonance imaging and CT in the diagnosis and prognostic evaluation of neonatal hypoxic ischemic encephalopathy
		XIAO Jian-hua1 ZHANG Hai-ping2 GUO Yan-ping1 WEI Liang1 DAI Zhen-zhao1
		Guide::
		Objective To analyze and compare the value of magnetic resonance imaging and CT in the diagnosis and prognostic evaluation of neonatal hypoxic ischemic encephalopathy (HIE)，and to provide a basis for clinical application.Methods A total of 80 cases of neonatal HIE who were treated in Affiliated Hospital of Jinggangshan University from September 2019 to January 2020 were retrospectively analyzed.All children were diagnosed according to the relevant criteria in the Diagnostic Criteria for Neonatal Hypoxic Ischemic Encephalopathy，and all of them underwent magnetic resonance imaging and CT examinations.The clinical diagnosis result were taken as the gold standard，the detection rate of neonatal HIE，diagnostic coincidence rate of the severity of disease and the detection rate of intracranial hemorrhage of two detection methods were compared.Results The detection rate of neonatal HIE and the diagnostic coincidence rate of the severity of disease of magnetic resonance imaging were higher than those of CT，the differences were statistically significant (P＜0.05).The detection rate of subarachnoid hemorrhage of CT was higher than that of magnetic resonance imaging，while the detection rate of basal ganglion hemorrhage of magnetic resonance imaging was higher than that of CT，the differences were statistically significant (P＜0.05).Conclusion Magnetic resonance imaging and CT can be used for the diagnosis of neonatal HIE.Among them，the diagnostic and prognostic value of magnetic resonance imaging is higher than that of CT，magnetic resonance imaging is easier to detect basal ganglion hemorrhage，and CT is more likely to detect subarachnoid hemorrhage.
		2020 Vol. 27 (33): 138-140 [Abstract] ( 14 ) HTML (33 KB) PDF (0 KB) ( 13 )

	141	Characteristic analysis of non-mass breast lesions by ultrasound and mammography
		QU Ting-ting
		Guide::
		Objective To analyze the characteristics and diagnostic value of ultrasound and mammography in non-mass breast lesions.Methods From January 2017 to July 2019，83 patients who were examined by ultrasound and mammography X-ray in the Third Hospital of Nanchang were selected.After surgery or ultrasound-guided needle biopsy，they were pathologically confirmed as non-mass breast lesions.The pathological diagnosis was regarded as gold standard.The ultrasonic and mammography X-ray characteristics of non-mass breast lesions were analyzed，and the area under the ROC curve was compared to compare the diagnostic value of the two methods alone and in combination.Results Among 83 cases of non-mass lesions breast，54 cases were malignant lesions and 29 cases were benign lesions.The diagnosis of non-mass breast lesions by ultrasound was characterized by flake hypoechoic area，detour of catheter with microcalcification，structural disorder，cluster or diffused microcalcification.The features of mammography X-ray in the diagnosis of non-mass breast lesions were calcification，structural distortion，structural asymmetry and local density thickening.The areas under the ROC curve of ultrasound，mammography and their combination (serial method and parallel method) were 0.819，0.827，0.779 and 0.866，respectively.The sensitivity of parallel method in the diagnosis of non-mass breast lesions was 87.04%，which was higher than that of ultrasound (74.07%)，mammography (72.22%) and combined series method (59.26%)，the difference was statistically significant (P＜0.05).There was no significant difference in the sensitivity of ultrasound in the diagnosis of non-mass breast lesions compared with mammography X-ray(P＞0.05).Conclusion Ultrasound and mammography X-ray have their own advantages and disadvantages in the diagnosis of non-mass breast lesions.The combined detection of ultrasound and mammography in parallel can improve the sensitivity of diagnosis and is beneficial to the detection of non-mass breast lesions.
		2020 Vol. 27 (33): 141-145 [Abstract] ( 13 ) HTML (41 KB) PDF (0 KB) ( 7 )

	146	Ultrasonographic features of acute appendicitis and its clinical diagnostic value analysis
		WANG Yong
		Guide::
		Objective To analyze the ultrasonographic features of acute appendicitis (AA) and its clinical diagnostic value.Methods A total of 171 cases of patients suspected with AA in Shangrao Municipal Hospital from November 2017 to October 2019 were selected as the research objects.All the patients were examined by ultrasound，and the diagnostic efficiency and ultrasonic image characteristics of different pathological types were observed.Results Among 171 suspected AA patients，150 cases were positive and 21 cases were negative，70 cases were simple appendicitis，59 cases were suppurative appendicitis and 21 cases were perforated appendicitis.The results of surgical pathology were used as the gold standard.The sensitivity，specificity and accuracy of ultrasound in the diagnosis of simple appendicitis were 84.29%，75.00% and 83.33%，respectively.The sensitivity，specificity and accuracy of ultrasound diagnosis of suppurative appendicitis were 93.22%，85.71% and 92.42%，respectively.The sensitivity，specificity and accuracy of diagnosing perforated appendicitis were 85.71%，100.00% and 88.89%，respectively.The incidence rates of dilation of lumen and unclear layers of wall in suppurative and perforated appendicitis were higher than those in simple appendicitis，the differences were statistically significant (P＜0.05).The incidence of intraluminal fecal stones in patients with perforated appendicitis was lower than that in patients with simple appendicitis，the difference was statistically significant (P＜0.05).The incidence of appendiceal effusion in patients with perforated appendicitis was higher than that in patients with simple appendicitis and suppurative appendicitis，the difference was statistically significant (P＜0.05).The incidence of lymphadenectasis in patients with simple appendicitis was higher than that in patients with perforated appendicitis and suppurative appendicitis，the difference was statistically significant (P＜0.05).The width of the appendix in patients with perforated appendicitis was larger than that in patients with suppurative appendicitis and simple appendicitis，the length of appendicitis and the thickness of tube wall in patients with simple appendicitis were shorter than those in patients with suppurative appendicitis and perforated appendicitis，the differences were statistically significant (P＜0.05).Conclusion The accuracy rate of ultrasound diagnosis of AA is higher，which has certain clinical value in the differential diagnosis of different pathological types of appendicitis，and can provide reference for clinical diagnosis and treatment plan.
		2020 Vol. 27 (33): 146-149 [Abstract] ( 12 ) HTML (35 KB) PDF (0 KB) ( 10 )

	150	Application of abdominal ultrasound with rectal water sac in infantile pelvic examination
		YI Jing-jia WANG Qiong PENG Hong-ling LI Li-zhu YAN Jia
		Guide::
		Objective To investigate the application value of abdominal ultrasound with rectal water sac in infantile pelvic examination.Methods The data of 50 female infants who underwent ultrasound examination in Pingxiang Maternal and Child Health Hospital from May 2018 to November 2019 were retrospectively analyzed.All children underwent conventional abdominal ultrasound examination and abdominal ultrasound examination with rectal water sac.The results of follow-up and serological examination assisted diagnosis were taken as the gold standard，the detection condition of two inspection methods was compared.Results The images of the ovaries and uterus during routine abdominal ultrasound examination were not clear enough，the transabdominal ultrasound with rectal water sac examination could more clearly show the structure of the uterus and ovaries of children.The display rate of abdominal ultrasound with rectal water sac in the diagnosis of uterus，ovaries and abdominal intestines was 92.00% (46/50)，which was higher than the 62.00% (31/50) of conventional abdominal ultrasound，and the difference was statistically significant (P＜0.05).The total coincidence rate of abdominal ultrasound with rectal water sac (90.00%) was higher than that of conventional abdominal ultrasound (28.00%)，and the difference was statistically significant (P＜0.05).Conclusion Compared with conventional abdominal ultrasound，abdominal ultrasound with rectal water sac can clearly show the uterine and ovarian structure，improve the accuracy of infantile pelvic examination，provide new options for the diagnosis of pelvic diseases in infants and young children，which provides guidance for the choice of clinical treatment plans.
		2020 Vol. 27 (33): 150-153 [Abstract] ( 13 ) HTML (35 KB) PDF (0 KB) ( 7 )

	154	Application value of DR and CT in the diagnosis of spinal blowout fractures
		FU Lian-shan1 LAN Xi-ling2 ZHOU Yu-yu1
		Guide::
		Objective To explore the application value of digital radiography (DR) and computed tomography (CT) in the diagnosis of spinal blowout fractures.Methods A total of 60 patients suspected with spinal blowout fracture from January 2018 to December 2019 in the Second People′s Hospital of Nankang District of Ganzhou City were selected as the research objects.According to the operation results，they were divided into the spinal blowout fracture patients (n=14) and the non-spinal blowout fracture patients (n=46).All patients underwent DR and CT examination before operation.The inspection time，examination cost and the coincidence rate of two different inspection methods were compared.The operation results were used as reference，the spinal blowout fracture diagnostic results and efficacy was analyzed.Results CT examination time was (8.47±1.49) min，which was longer than that of DR examination time ([2.36±0.85]min)，the difference was statistically significant (P＜0.05).CT examination cost was (645.32±51.94) yuan，which was higher than that of DR examination cost ([110.87±23.15]yuan)，the difference was statistically significant (P＜0.05).The coincidence rate of CT diagnosis of spinal blowout fracture was 92.86%，which was higher than that of DR (57.14%)，the difference was statistically significant (P＜0.05).The coincidence rates of bone fragments，vertebral displacement，spinal stenosis and vertebral fracture line of CT diagnosis were 78.57%，83.33%，84.62% and 85.71%，respectively，which were higher than those of DR diagnosis of spinal burst fractures (35.71%，41.67%，30.77% and 35.71%，respectively)，and the differences were statistically significant (P＜0.05).The sensitivity，specificity and accuracy of CT in the diagnosis of spinal burst fractures were 85.71%，97.83% and 95.00%，which were higher than 35.71%，78.26% and 68.33% of DR diagnosis，and the differences were statistically significant (P＜0.05).The missed diagnosis rate and misdiagnosis rate of CT were 14.29% and 2.17%，which were lower than 64.29% and 21.74% of DR diagnosis，and the differences were statistically significant (P＜0.05).Conclusion Compared with DR examination，CT examination in the diagnosis of spinal blowout fractures can effectively clarify the status of patients with vertebral injuries，improve the diagnostic efficiency of spinal burst fractures，reduce missed diagnosis and misdiagnosis，but the inspection time is longer and the examination cost is higher.
		2020 Vol. 27 (33): 154-157 [Abstract] ( 15 ) HTML (35 KB) PDF (0 KB) ( 9 )

	158	Effect of CT examination in the differentiation between serous and mucinous tumors in ovarian borderline tumors
		ZHU Feng
		Guide::
		Objective To investigate and analyze the effect of CT examination in the differentiation of serous and mucinous tumors in ovarian borderline tumor (BOT).Methods From July 2018 to July 2019，37 patients with ovarian serous borderline tumor and 40 patients with ovarian mucinous borderline tumor treated in Anshan Central Hospital，were selected as study subjects.They were selected as the serous BOT group and the mucinous BOT group，respectively.CT examination was performed in both groups.CT morphological and imaging features were compared between the two groups.Results The number of sac compartmentalization in the mucinous BOT group was higher than that in the serous BOT group，the proportion of sac diameter ≥10 cm in the mucinous BOT group was larger than that in the serous BOT group，the differences were statistically significant (P＜0.05).The clear tumor boundary rate in the mucinous BOT group was higher than that in the serous BOT group，nevertheless，the homogeneous ratio of bag fluid density in the mucinous BOT group was lower than that in the serous BOT group，and the proportion of solid components in the mucinous BOT group was also lower than that in the serous BOT group，the differences were statistically significant (P＜0.05).In soft tissue form，the soft tissue morphology in the mucinous BOT group was mainly cystic wall and septal thickening，while the soft tissue in the serous BOT group was mainly distributed in map shape，and the difference was statistically significant (P＜0.05).Conclusion The imaging features of serous and mucinous tumors in ovarian borderline tumors differ greatly during CT examination，CT examination can provide important reference for their differentiation.
		2020 Vol. 27 (33): 158-160 [Abstract] ( 11 ) HTML (28 KB) PDF (0 KB) ( 7 )

	161	Application value of chemiluminescence immunoassay technology in the biochemical immunity test of patients with thyroid tumor
		SHI Jian-xiong
		Guide::
		Objective To analyze the application value of chemiluminescence immunoassay technology in the biochemical immunoassay test of patients with thyroid tumor.Methods A total of 120 patients suspected with thyroid tumor who were treated in Anshan Central Hospital from June 2017 to June 2019 were selected as the research objects.They were divided into the experimental group and the control group by computer random method，with 60 cases in each group.The venous blood of the patients was drawn.The patients in the control group were tested by radioimmunoassay，and the patients in the experimental group were tested by chemiluminescence immunoassay technology.Compared with the pathological diagnosis results，the coincidence rate，sensitivity，and specificity of the two groups were analyzed.Results The test coincidence rate (93.33%)，sensitivity (93.75%)，and specificity (92.85%) of the experimental group were higher than those of the control group (76.66%，73.33%，73.33%)，and the differences were statistically significant (χ2=8.643，4.772，3.865，P＜0.05).Conclusion Using chemiluminescence immunoassay technology to test patients with thyroid tumors can effectively improve the coincidence rate，sensitivity and specificity of the test，and has clinical promotion value.
		2020 Vol. 27 (33): 161-163 [Abstract] ( 12 ) HTML (29 KB) PDF (0 KB) ( 6 )

	164	Changes and significance of biochemical test items in patients with liver cirrhosis
		JI Jin-ling CHENG Xiao-tong WANG Qian ZHU Tian-xing YANG Jiao-na
		Guide::
		Objective To analyze the changes and significance of biochemical test items in patients with liver cirrhosis.Methods A total of 160 patients with liver cirrhosis who were treated in Liaoyang Infectious Disease Hospital from June 2017 to June 2019 were randomly selected as the observation group.Among them，53 patients were in the early stage (33.13%)，53 patients were in the middle stage (33.13%)，and 54 patients (33.75%) were in the late stage.Then 160 healthy people who came to the hospital for physical examination during the same time period were selected as the control group.The venous blood samples of the two groups were collected and used as biochemical test samples，and then the main biochemical test items were tested with an automatic biochemical analyzer to compare the biochemical test items of the two groups.Results The levels of N-acetyl-β-d glucosaminidase (NAG)，α-fucosidase (AFU)，prealbumin (PAB)，leucine aminopeptidase (LAP)，aspartate amino transfer isoenzyme (ASTm)，glutamate dehydrogenase(GLDH)，adenosine deaminase (ADA) and α-fetoprotein (AFP) in the observation group were higher than those in the control group，and the differences were statistically significant (P＜0.05).The levels of NAG，AFU，PAB，LAP，ASTm，GLDH，ADA，and AFP in the advanced patients were higher than those in the early and middle stage patients，while NAG，AFU，PAB，LAP，ASTM，GLDH，ADA，and AFP levels in the middle stage patients were higher than those in the early stage patients，the differences were statistically significant (P＜0.05).Conclusion The implementation of biochemical test items for diagnosis of patients with liver cirrhosis in the clinic can provide effective reference value for later clinical treatment and promote a significant increase in clinical accuracy.
		2020 Vol. 27 (33): 164-166 [Abstract] ( 11 ) HTML (30 KB) PDF (0 KB) ( 6 )

	167	Analysis of the correlation between the therapeutic effect and psychological status of gout patients
		ZHANG Xue-zhen1 CHEN Xiao-ying2 TAN Zhi-ming3 ZHUANG Yu3 TAO Yi1 HUANG Wen-hui1▲
		Guide::
		Objective To explore the correlation between the therapeutic effect and psychological status of gout patients，and to provide reference for their clinical treatment and quality of life improvement.Methods From September 2018 to September 2019，200 patients diagnosed as gout in Huizhou Central People′s Hospital were selected as the research objects.After 20 weeks of standardized application of drugs，the therapeutic effect indexes of patients were evaluated before and after treatment，mainly including clinical symptom integral evaluation of gout，fasting blood uric acid level，erythrocyte sedimentation rate，C-reactive protein，ultrasonic image change indexes，monitoring liver and kidney function indexes to evaluate the drug safety and psychological status of patients with gout，and explore the correlation between the therapeutic effect and psychological status.Results There were no significant differences in serum alanine aminotransfease (ALT) and aspartate aminotransferase (AST) between the two groups before and after treatment (P＞0.05).After treatment，the levels of urea nitrogen (BUN)，creatinine，uric acid，synovium thickness，self-rating anxiety scale (SAS) and self-rating depression scale (SDS) were lower than those before treatment (P＜0.05);after treatment，the synovial thickness was lower than that before treatment，and the blood flow signal pannus resistance index (RI) was higher than that before treatment (P＜0.05).SAS and SDS scores were positively correlated with BUN，creatinine，serum uric acid and synovial thickness，and negatively correlated with RI (P＜0.05).Conclusion The clinical symptoms，inflammatory indexes，serum uric acid level，ultrasound imaging results and psychological state of patients treated with Febuxostat combined with celecoxib were significantly improved.
		2020 Vol. 27 (33): 167-170 [Abstract] ( 14 ) HTML (41 KB) PDF (0 KB) ( 8 )

	171	Influence of prescription review on the rationality of outpatient and emergency prescriptions
		DAI Ke-min
		Guide::
		Objective To explore the influence of prescription review on the rationality of outpatient and emergency prescriptions.Methods The prescription data of 1000 outpatients and emergency patients from January 2017 to December 2018 were selected as the research objects，all of which had complete clinical data.Among them，the clinical data of 500 outpatients and emergency patients admitted from January to December 2017 were taken as the control group(without prescription comment intervention)，and the clinical data of 500 outpatients and emergency patients admitted from January to December 2018 were taken as the study group (with prescription comment intervention implemented).The relevant provisions in the Prescription Management Measures was referred，to supervise and evaluate the prescription review，and analyze the review with SPSS 20.0 statistical software to analyze the rationality of the prescription.Results The proportion of inappropriate prescription type in the study group was 1.20%，which was lower than that in the control group (3.60%)，the difference was statistically significant (P＜0.05).The rate of irregular prescriptions in the study group was 2.60%，which was lower than that in the control group (8.00%)，the difference was statistically significant (P＜0.05).Conclusion The implementation of prescription review can help to improve the rational rate of drug use in medical institutions.Through the use of the corresponding review software，it can help to improve the efficiency of the application of review methods，so as to improve the rationality of prescription.At the same time，it is necessary to strengthen the standardization of prescription writing.
		2020 Vol. 27 (33): 171-173 [Abstract] ( 13 ) HTML (29 KB) PDF (0 KB) ( 8 )

	174	Analysis of adverse drug reactions in Pizhou People′s Hospital in 2018
		SHAO Hai-yan WANG Qian
		Guide::
		Objective To analyze adverse drug reactions in Pizhou People′s Hospital (hereinafter referred to as "our hospital") in 2018.Methods A total of 318 adverse drug reaction reports from January to December 2018 of our hospital were analyzed.The general situation，severity of adverse reactions，patient′s primary diseases，previous adverse drug history，family adverse drug history，types of adverse drugs，dosage forms，routes of administration，main manifestations and results of adverse reactions were analyzed.Results Altogether 188 were males (59.12%) and 130 were females(40.88%);the highest proportion was ＞40-60 years old，accounting for 35.85%.Respiratory diseases accounted for 25.79% of the patient′s primary diseases.The proportions of Chinese patent medicine and antibacterial medicine were higher，accounting for 30.19% and 15.72% respectively.The main dosage forms were oral dosage form and injection powder injection，accounting for 55.56% and 42.14% respectively;in the route of administration，the proportions of oral and intravenous drugs were higher，accounting for 55.35% and 41.82% respectively.The main adverse reactions were gastrointestinal symptoms，allergic reactions and nervous system reactions，accounting for 39.62%，36.16% and 14.15%respectively，among which 4 patients had shock.306 cases improved，accounting for 96.23%，10 cases recovered，accounting for 3.14%.Conclusion From January to December 2018，the ADR patients in our hospital are mainly middleaged and elderly people.The proportion of Chinese patent medicine and antibacterial medicine is relatively high，and the proportion of oral and injection minute injection is relatively high.Most of them are general ADRs，but some patients have severe shock，and most of them have improved or recovered.
		2020 Vol. 27 (33): 174-176 [Abstract] ( 12 ) HTML (30 KB) PDF (0 KB) ( 12 )

	177	Retrospective analysis of 1009 adverse drug reaction reports from Lu′an Hospital of Traditional Chinese Medicine from 2017 to 2019
		WANG Jun LIU Meng ZHU Chun-feng HE Yang WANG Kun WU Liang
		Guide::
		Objective To master the characteristics and regularity of adverse drug reaction (ADR) of Traditional Chinese Hospital of Lu′an，and improve the safety of drug use.Methods A retrospective analysis was performed on 1009 ADR reports collected by Traditional Chinese Hospital of Lu′an and reported to the National Adverse Drug Reaction Detection System from January 2017 to December 2019.Results Among the 1009 ADR reports，most of them occurred in middle-aged and elderly patients;males had higher risk of ADR than females;antitumor drugs，contrast agents，anti microbial drugs occupied the highest proportion (60.1%);injection types of drug were the main forms of drugs which led to ADR;the major systems involved were digestive system，cardiovascular system，skin and its appendages;about 91.2% of the patients recovered or improved after these adverse reactions;the main occupation of the reporters were nurses.Conclusion In order to improve the safety drug use and reduce the occurrence of ADR，greater attention should be paid to the elderly people and the patients who use antitumor drugs，contrast agents and anti microbial drugs.
		2020 Vol. 27 (33): 177-180 [Abstract] ( 17 ) HTML (34 KB) PDF (0 KB) ( 8 )

	181	Effectiveness analysis of PDCA cycle management model on the improvement of quality of work of pharmacy intravenous admixture services
		MA Ke1，2 ZHANG Hong1▲
		Guide::
		Objective To analyze the effect of PDCA circulation management mode on improving the quality of work of pharmacy intravenous admixture services (PIVAS).Methods The management implemented by PIVAS in Luoyang Orthopedic-Traumatological Hospital of Henan Province from January to December 2018 was set as the control group，the management implemented from January to December 2019 was set as the observation group.The conventional management mode was assigned to the control group，and the observation group implemented the PDCA cycle management model.The drug dispensing speed，the rate of drug dispensing error and the rate of drug loss were compared between the two groups.Results The dispensing speed of the observation group was(1.42±0.17)bags per minute，which was higher than that of the control group ([1.19±0.21]bags per minute).The dispensing error rate of the observation group was 0.018%，which was lower than that of the control group of 0.048%，the difference was statistically significant (χ2=132.0，P＜0.05).The drug loss rate of the observation group was 0.006%，which was lower than that of the control group of 0.013%，the difference was statistically significant (χ2=25.6，P＜0.05).Conclusion By analyzing and summarizing a series of reasons for the low quality of PIVAS，using PDCA circulation management mode and taking targeted measures and continuous improvement，the speed of PIVAS configuration in Luoyang Orthopedic-Traumatological Hospital of He′nan Province has been significantly accelerated，the drug dispensing error rate and drug consumption rate have also been greatly reduced，and the work quality of PIVAS has been greatly improved.
		2020 Vol. 27 (33): 181-183 [Abstract] ( 13 ) HTML (31 KB) PDF (0 KB) ( 11 )

	184	Application and discussion of establishing oral single disease management system based on outpatient electronic medicald record
		CAI Jian1 ZHU Chan-yuan2▲
		Guide::
		Objective To explore the application effect of establishing oral single disease management system based on outpatient electronic medical record.Methods Related data of 7928 cases of stomatology specialty which were not implemented based on outpatient electronic medical records in Affiliated Stomatological Hospital of Nanchang University in 2018 were collected.At the same time，the related data of 10 066 cases of stomatology specialty were collected after the establishment of oral single disease management system information platform based on outpatient electronic medical records in 2019.The changes of medical safety indicators (imaging examination，informed consent of patients) and medical quality indicators (complications and satisfaction) before and after implementation were compared.Results The execution rate of imaging examination and the execution rate of patients′ informed consent in 2019 were 99.18% and 96.71%，which were higher than those in 2018 ( 96.83% and 78.43%)，the differences were statistically significant (P＜0.05).The incidence rate of complications in 2019 was 1.56%，which was lower than 1.96% in 2018，the differences were statistically significant (P＜0.05).The satisfaction degree of patient in 2019 was 99.79%，which was higher than 99.46% in 2018，the difference was statistically significant(P＜0.05).Conclusion The establishment of oral single disease management system based on the electronic medical records of outpatient clinics can standardize the diagnosis and treatment behavior，improve the execution rate of medical safety operations，reduce the occurrence of complications，and the satisfaction degree of patient is higher.
		2020 Vol. 27 (33): 184-187 [Abstract] ( 10 ) HTML (35 KB) PDF (0 KB) ( 9 )

	188	Application of PDCA cycle in quality management of drug clinical trials
		SONG Ji-wei
		Guide::
		Objective To explore the application effect of PDCA cycle in quality management of drug clinical trials，and to provide reference for improving quality management of drug clinical trials.Methods Since January 2019，PDCA cycle theory had been applied in the quality management of drug clinical trials of Jilin City People′s Hospital.First of all，management related problems during the implementation of drug clinical trials in Jilin City People′s Hospital from January to December 2018 were analyzed and summarized，and the relevant improvement measures were formulated to implement the PDCA cycle achieve continuous improvement.The occurrence of related problems in the course of drug clinical trial，such as non-standard record of case report，program deviation，adverse event reporting problem，trial drug management problem and informed consent problem before (2018) and after PDCA circulation theory implementation(2019) were compared，and the quality improvement effect after the implementation of PDCA circulation theory was analyzed.Results After the implementation of PDCA circulation theory in 2019，the total incidence of quality management related problems in drug clinical trials was 1.84%，which was lower than 10.17% in 2018，and the difference was statistically significant (P＜0.05).Conclusion The application of PDCA cycle in the quality management of drug clinical trials can improve the quality management model and improve the management quality of drug clinical trials.
		2020 Vol. 27 (33): 188-190 [Abstract] ( 17 ) HTML (29 KB) PDF (0 KB) ( 11 )

	191	Application effect of operation room access training in intern teaching
		WANG Yu-qian LIU Jiang-hong LUO Xu-yang
		Guide::
		Objective To explore the application effect of operating room access training in interns teaching.Methods A total of 100 junior college interns in Jiangxi Chest Hospital from September 2018 to December 2019 were selected and divided into the experimental group and the control group according to random number table method，with 50 interns in each group.The experimental group received operating room access training，while the control group received routine training.The hand hygiene assessment score，the incidence of potential hospital infection events during the internship，and the teaching satisfaction score between the two groups were compared.Results The hand hygiene assessment score and teaching satisfaction score of the experimental group were higher than those of the control group，the differences were statistically significant (P＜0.05).The incidence of potential hospital infection events in the experimental group was lower than that in the control group，the difference was statistically significant (P＜0.05).Conclusion Compared with the conventional pre-job training for operating room interns，the access training method of operating room has more advantages，which can effectively improve interns′ satisfaction with operating room teaching，increase the pass rate of hand hygiene，reduce the occurrence of potential nosocomial infection in operating room caused by interns，so as to enhance the teaching effect and increase the safety of operation.
		2020 Vol. 27 (33): 191-193 [Abstract] ( 13 ) HTML (30 KB) PDF (0 KB) ( 8 )

	194	Effect comparison between flipped class model teaching method and traditional teaching method in clinical teaching of cardiopulmonary resuscitation
		LIU Juan CHEN Xiu-li LIU Wei-ping
		Guide::
		Objective To explore the application effect of flipped class model (FCM) teaching method and traditional teaching method in clinical teaching of cardiopulmonary resuscitation.Methods From January to December 2018，67 nursing students were selected as the control group，using traditional teaching methods;from January to December 2019，67 nursing students were selected as the observation group，using FCM teaching methods.The test results and self-learning ability (self-directed learning readiness scale for nursing education [SDLRS]) scores of the two groups were compared，and the satisfaction of nursing students with teaching was investigated.Results The theoretical score in the observation group was (93.24±5.12) points，and the operation score was (94.52±3.16) points，which were higher than those in the control group of (85.69±5.47) and (87.53±4.17) points，the differences were statistically significant (P＜0.05).The self-management score in the SDLRS of the observation group was (56.87±3.26) points，the self-control score was(63.54±4.23) points，and the enthusiasm of learning score was (48.69±3.15) points，and the total score was (167.98±11.63) points，which were higher than (50.21±3.24)，(56.32±4.22)，(44.65±3.18)，(152.94±10.57) points of the control group，the differences were statistically significant (P＜0.05).The total teaching satisfaction of the observation group was 97.01%，which was higher than 82.09% of the control group，and the difference was statistically significant (P＜0.05).Conclusion FCM is effective in the application of clinical cardiopulmonary resuscitation teaching.It can improve the level of theoretical knowledge and operational skills of students，cultivate the ability of independent learning and improve the satisfaction of teaching.
		2020 Vol. 27 (33): 194-196 [Abstract] ( 13 ) HTML (32 KB) PDF (0 KB) ( 8 )

	197	Practice of TBL teaching in experiment teaching of medical biochemistry
		YANG Yi FANG Wei-shan KANG Kang ZHANG Li XIA Li-xin▲
		Guide::
		Traditional medical education is mainly based on theoretical indoctrination，supplemented by mechanical experiment teaching，which is increasingly unable to meet the requirements of modern medical development for the cultivation of high-quality medical students.In the medical undergraduate biochemistry experiment teaching，the teaching practice reform of TBL teaching can be used to achieve the teaching goal of increasing more clinical application knowledge in the medical biochemistry experiment course by using the effective method of low cost，time and effort.The TBL teaching model improves some of the deficiencies in traditional experimental teaching for the expected teaching goals，for example，to enhance students′ active learning ability，to improve students′ teamwork and communication skills，to strengthen the teacher-student interaction and to achieve the teaching harmony.
		2020 Vol. 27 (33): 197-200 [Abstract] ( 14 ) HTML (34 KB) PDF (0 KB) ( 13 )

	201	Application effect comparison of implantable venous access port and peripherally inserted central catheter in chemotherapy of gynecological malignant tumors
		WAN Xiao-lan WU Zhen WANG Hua-ling
		Guide::
		Objective To explore of application effect of implantable intravenous infusion port (VAP) and peripherally inserted central catheter (PICC) in chemotherapy of gynecological malignant tumors.Methods From October 2018 to October 2019，100 patients with gynecological malignant tumors who were admitted to Jiangxi Provincial Cancer Hospital for chemotherapy were selected.They were divided into PICC and VAP groups according to the random number table method，50 cases in each group.In the PICC group，patients received PICC chemotherapy and nursing，and in the VAP group，participants received VAP chemotherapy and nursing.The observation lasted 6 months.The operation，retention，maintenance operation time and complications of the two groups were compared.Results The operation time of cathetering maintenance in the VAP group was(11.25±2.14)min，shorter than that in the PICC group of(14.79±3.08)min，with statistical difference (P＜0.05).In the VAP group，the success rate of one-time cathetering was 98.00%，not statistically different from that in the PICC group accounting for 94.00% (P＞0.05).The retention rate of the VAP group within 6 months was 86.00%，higher than that in the PICC group accounting for 68.00%，and the difference was statistically significant (P＜0.05).The total incidence of complications in the VAP group was 8.00%，lower than that in the PICC group accounting for 24.00%，and the difference was statistically significant (P＜0.05).Conclusion The application effect of VAP in chemotherapy of gynecological malignant tumors is better than that of PICC，which can increase the retention rate，shorten the operation time of catheter maintenance and reduce the occurrence of complications.
		2020 Vol. 27 (33): 201-203 [Abstract] ( 9 ) HTML (31 KB) PDF (0 KB) ( 8 )

	204	Nursing study of Wevar light promoting healing of immune ulcers
		YU Jin1 HUANG Zhan-mei2▲ WU Rui2 XU Xiao-ting2 XIONG Wei2 CHEN Jiao1
		Guide::
		Objective To explore the nursing measures of Wevar to promote the healing of immune ulcers.Methods A total of 100 patients with rheumatic immune diseases and skin ulcers admitted to the First Affiliated Hospital of Nanchang University from June 2018 to December 2019 were selected and divided into control group and research group according to random number table method，50 cases in each group.The control group was divided into group A and group B：group A adopted traditional wound care technology，group B adopted new dressing wound care technology;research group was divided into group C and group D：group C used Wevar irradiation and traditional wound care technology，group D used Wevar irradiation and new dressing wound care technology，and they intervened for 3 months.The wound healing effect，wound dressing change times and medical expenses of the four groups were compared.Results After 3 months of intervention，the wound healing effect of group B was better than that of group A，the wound healing effect of group D was better than that of group C，and the wound healing effect of research group was better than that of control group，the differences were statistically significant (P＜0.05);the number of wound dressing changes and medical expenses in group B were lower than those in group A，the number of wound dressing changes and medical expenses in group D were lower than those in group C，and the number of wound dressing changes and medical expenses in the research group were lower than those in the control group (P＜0.05).Conclusion Wevar combined with wound care technology can accelerate the healing of immune ulcers，reduce the number of dressing changes，and reduce medical expenses.
		2020 Vol. 27 (33): 204-206 [Abstract] ( 11 ) HTML (34 KB) PDF (0 KB) ( 12 )

	207	Effect of extended care on compliance of antiviral medication and family support in elderly patients with acquired immunodeficiency syndrome
		HUANG Cha-ying WU Ai-lian HU Xue-dan LUO Lian-hua XIAO Xiao-lan
		Guide::
		Objective To study the effect of extended care on compliance of antiviral medication and family support in elderly patients with acquired immunodeficiency syndrome (AIDS).Methods Eighty elderly AIDS patients admitted to Jiangxi Chest Hospital from June 2018 to July 2019 were selected，and they were divided into control group and test group by random number table method，40 cases in each group.The control group received routine care and the test group used extension nursing，the medication compliance，quality of life and family support of patients of the two groups at 6 months after nursing were compared.Results There were no statistically significant differences in the compliance score and social support score between two groups before nursing (P＞0.05);the compliance score was (7.05±0.41) points and social support score was (23.12±3.58) points in the test group，which were high after nursing than those in the control group of (5.96±0.74) and (14.61±3.29) points，the differences were statistically significant (P＜0.05).The quality of life score comparison between the groups before nursing，the difference was not statistically significant(P＞0.05);nursing the post-test group′s physiological function，physical pain，physiological function，vitality，general health status，emotional function，social function and mental health scores were higher than those of the control group，the differences were statistically significant (P＜0.05).Conclusion The implementation of extended care for elderly AIDS patients can effectively improve their compliance with antiviral medication and social support level，and improve the quality of life.
		2020 Vol. 27 (33): 207-210 [Abstract] ( 13 ) HTML (35 KB) PDF (0 KB) ( 6 )

	211	Application of the concept of enhanced recovery after surgery in the perioperative nursing care of patients undergoing transurethral endoscopic nephrectomy
		HUANH YU-lan LAI Xiang-yan MENG Mei-ying ZHANG Zi-yu HUANG Wen-xiang ZHANG Guo-xi ZOU Xiao-feng
		Guide::
		Objective To explore the application effect of enhanced recovery after surgery (EARs) concept on perioperative nursing of patients undergoing urological surgery with transvaginal natural cavity endoscopic surgery(NOTES).Methods A total of 40 cases of patients with transvaginal NOTES nephrectomy who were admitted to the First Affiliated Hospital of Gannan Medical University from January 2017 to December 2019 were selected and divided into control group (n=18) and research group (n=22) according to different nursing methods.The indexes of the first postoperative exhaust time，the postoperative time of getting out of bed，the postoperative eating time，the postoperative complication rate，the postoperative hospital stay，and the patient satisfaction were compared between the two groups.Results The time of the first postoperative exhaustion，the time of getting out of bed，the time of first eating after the operation，and the time of postoperative hospital stay in the research group were shorter than those in the control group，the differences were statistically significant (P＜0.05).The total incidence of postoperative complications in the research group was 4.55%，which was lower than 27.78% in the control group，the difference was statistically significant (P＜0.05).The total satisfaction of patients in the research group was 95.45%，which was higher than 77.78% in the control group，the difference was statistically significant (P＜0.05).Conclusion The application of health education and nursing model under the concept of EARs in perioperative care of patients undergoing transvaginal NOTES nephrectomy can promote the postoperative rehabilitation process of patients，reduce the incidence of complications and improve patients nursing satisfaction.
		2020 Vol. 27 (33): 211-214 [Abstract] ( 12 ) HTML (37 KB) PDF (0 KB) ( 8 )

	215	Design of anti-drooped foot mat lifting for lower limb and application effect in stroke patients
		HUANG Ying-lan XIAO Li▲ XIAO Qian
		Guide::
		Objective To design anti-drooped foot mats lifting for lower limb and explore the application effect in stroke patients.Methods A total of 102 cases of stroke patients treated in Ganzhou People′s Hospital，Jiangxi Province from June 2018 to June 2019 were selected，and were divided into experimental group (n=51) and control group (n=51)in order of time of admission.Patients in the experimental group were given anti-drooped foot mats lifting for lower limb，the control group were given traditional T-shaped shoes or orthopedic mat，the incidence of deep venous thrombosis，strephenopodia，drooped foot and compliance of families were compared.Results The incidence rates of deep venous thrombosis，strephenopodia and drooped foot in the experimental group were lower than those of the control group，and the compliance of families was higher than that in control group，the differences were statistically significant (P＜0.05).Conclusion The application of self-made anti-drooped foot mats lifting for lower limb can reduce the incidence of venous thrombosis，strephenopodia，drooped foot of patients and can improve the using compliance of families.
		2020 Vol. 27 (33): 215-217 [Abstract] ( 11 ) HTML (31 KB) PDF (0 KB) ( 13 )

	218	Nursing experience of 43 patients with psoriasis vulgaris treated with medical trioxygenation
		LIU Yan-qin TAO Hong-bo LIU Bin▲
		Guide::
		Objective To summarize the nursing points and points for attention of patients with psoriasis vulgaris treated with medical trioxygenation.Methods A total of 43 patients with psoriasis vulgaris admitted to Wuhan Wudong Hospital from May 2016 to April 2019 were analyzed retrospectively.The nursing intervention and precautions during the period of medical trioxygenation were analyzed and summarized.Results After systematic medical trioxygenation treatment and careful nursing，most of the patients′ skin lesions disappeared，clinical symptoms basically disappeared or significantly improved，the condition was effectively controlled，the total effective rate was 74.4%.Conclusion When the patients with psoriasis vulgaris are treated with trioxygenation，they are given systematic and effective nursing measures and positive psychological support，with significant effect.
		2020 Vol. 27 (33): 218-221 [Abstract] ( 11 ) HTML (35 KB) PDF (0 KB) ( 9 )

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