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Quick Search     Adv Search 2021 Vol. 28, No. 13 Published: 2021-05-08   4 Meta-analysis of the effect of perioperative platelet transfusion on prognosis in adult patients undergoing cardiac surgery XIN Ming-xiu；ZHENG Hong；XING Chang-shuang；MA Hai-ping Objective To use Meta-analysis to compare the effect of perioperative platelet transfusion and non-platelet transfusion on the prognosis of adult cardiac surgery patients,so as to provid clinical evidence of evidence-based medicine.Methods Retrospective studies on the effect of perioperative platelet transfusion on prognosis in adult patients undergoing cardiac surgery were searched from China National Knowledge Infrastructure,Wanfang,China Biomedical Literature Database,EMbase and PubMed databases.The retrieval time was from January 2000 to July 2020.Review Manager 5.4 software was used for Meta-analysis.Results Eight retrospective studies involving 36 654 patients were included in this study.Of all patients enrolled in the study,17%(6232/36 654)received perioperative platelet transfusion and 83%(30 422/36 654)did not receive platelet transfusion.The results of Meta-analysis showed that there were no significant differences in 30 d postoperative death,number of reoperations,postoperative blood transfusion,operative time and ICU retention time between the platelet transfusion group and the non-transfusion group during the perioperative period of heart surgery(P>0.05).However,the postoperative infection in the platelet infusion group was higher than that in the non-platelet infusion group(RR=0.03,95%CI: 0.00-0.05,P=0.04),and the number of patients with myocardial infarction was also higher than that in the non-platelet infusion group(RR=1.78,95%CI: 1.18-2.70,P=0.008),with statistical significances.Conclusions Perioperative platelet transfusion and non-transfusion of platelets in adult cardiac surgery patients had no significant effect on postoperative complications,mortality,operative time,and ICU retention time,but platelet transfusion can increase the incidence of postoperative infection and myocardial infarction. 2021 Vol. 28 (13): 4-7-28 [Abstract] ( 42 ) HTML (39 KB)  PDF  (0 KB)  ( 7 ) 8 Clinical value of digital X-ray imaging system chest radiograph combined with high-frequency CT in the diagnosis of occupational pneumoconiosis OU Xiong-zhang Objective To explore the value of digital X-ray imaging system(DR)chest radiograph combined with highfrequency CT(HRCT)in the diagnosis of occupational pneumoconiosis.Methods A total of 45 patients with occupational pneumoconiosis diagnosed in Qingyuan Chronic Disease Prevention and Treatment Hospital from January 2018 to September 2020 were retrospectively selected as the research subjects,and all were examined by DR chest radiograph and HRCT.The display rates of P shadow,small shadow and large shadow,identification of disease stages,and the coincidence rate of related complications were compared by DR chest radiograph,HRCT examination alone and combined.The imaging quality was compared between DR chest radiograph and HRCT alone.Results The display rate of P shadow of DR chest radiograph combined with HRCT(80.00%)was higher than that of HRCT and DR chest radiograph(60.00%,42.22%),and the differences were statistically significant(P＜0.05).The display rate of small shadow of DR chest radiograph combined with HRCT and HRCT(22.22%,17.78%)was higher than that of DR chest radiograph(2.22%),and the differences were statistically significant(P＜0.05).The overall coincidence rate of DR chest radiograph combined with HRCT and HRCT in the diagnosis of pneumoconiosis(100.00%,93.33%)was higher than that of DR chest radiograph(71.11%),and the differences were statistically significant(P＜0.05).The coincidence rate of DR chest radiograph combined with HRCT to differentiate stage Ⅰpneumoconiosis(57.78%)was higher than that of DR chest radiograph(35.56%),and the difference was statistically significant(P＜0.05).The coincidence rates of DR chest radiograph combined with HRCT and HRCT in the identification of emphysema,pleural thickening,pneumothorax,and bullae were higher than those of DR chest radiograph,and the differences were statistically significant(P＜0.05).The imaging quality of HRCT was higher than that of DR chest radiograph,the difference was statistically significant(P＜0.05).Conclusion The combined application of DR chest radiograph and HRCT in the diagnosis of occupational pneumoconiosis can improve the display rate of P shadow and the accuracy of disease staging and complication identification. 2021 Vol. 28 (13): 8-11 [Abstract] ( 52 ) HTML (35 KB)  PDF  (0 KB)  ( 7 ) 12 Clinical effect of Bortezomib combined with Dexamethasone in the treatment of elderly patients with multiple myeloma MI Hong-yan；YANG Qiu-an；SUN Yan-qing Objective To investigate the clinical effect of Bortezomib combined with Dexamethasone(BD)in the treatment of senile multiple myeloma(MM).Methods A total of 100 elderly patients with MM who were admitted to Qilu Hospital of Shandong University and Gansu People′s Hospital from February 2012 to February 2020 were retrospectively selected as the research objects.According to different treatment regimen,they were divided into BD group(50 cases)and TD group(50 cases).The BD group was treated with Bortezomib combined with Dexamethasone regimen,while the TD group was treated with Thalidomide combined with Dexamethasone regimen.The clinical efficacy,the incidence of adverse reactions and the survival of two groups were compared.Results The total effective rate and the effective rate in the newly treated patients in BD group were higher than those in TD group,and the differences were statistically significant(P＜0.05).The increase value of hemoglobin,decrease value of serum creatinine,decrease value of serum β2 microglobulin and decrease value of plasma cell proportion in bone marrow in BD group were higher than those in TD group,and the differences were statistically significant(P＜0.05).After 4-50 months of follow-up,the survival time and survival rate in BD group were higher than those in TD group,and the differences were statistically significant(P＜0.05).The incidence of fatigue,peripheral neuropathy and myelosuppression in BD group were higher than those in TD group,and the incidence of constipation,rash,drowsiness,dizziness and deep vein thrombosis were lower than those in TD group,the differences were statistically significant(P＜0.05).There were no significant differences in the incidence of abdominal pain,diarrhea and herpes zoster between the two groups(P＞0.05).Conclusion The efficacy of BD in the elderly patients with MM is significant,and the safety is high,which is worthy of clinical promotion. 2021 Vol. 28 (13): 12-16 [Abstract] ( 52 ) HTML (43 KB)  PDF  (0 KB)  ( 13 ) 17 Study on molecular mechanisms of Akebia Decne in treatment of urinary system diseases based on network pharmacology WU Geng-fan Objective To explore the active components and molecular mechanism of Akebia Decne in the treatment of urinary system diseases from the perspective of network pharmacology.Methods Active ingredients and targets were obtained through Traditional Chinese Medicines Systems Pharmacology(TCMSP),urinary disease-related targets were obtained through OMIM and Genecard databases,and the active ingredients-targets network was bulit by using cytoscape_3.7.2.Through the STRING database,the protein-protein interaction network was constructed,and the core targets were obtained by network topology analysis with Bisogenet plug-in of Cytoscape.Then Autodock vina was used to verify the molecular docking between the active ingredients and the targets.Finally,core targets data were imported into Metascape to obtain GO biological process enrichment analysis and KEGG pathway enrichment analysis.Results The active ingredient-targets network of Akebia Decne involved 8 active ingredients and 51 targets.The results of docking showed that the active ingredients had good binding ability with the corresponding targets.Twenty GO biological process analysis and 20 KEGG pathways were determined.GO biological process analysis mainly involved apoptotic signaling pathway,cell division,cellular response to nitrogen compound,cellular response to oxidative stress and regulation of cellular response to stress.KEGG pathway analysis results showed that the regulation of the urinary system mainly involved MAPK pathway,mitochondrial autophagy,p53 signaling pathway and bacterial infection.Conclusion The treatment of urinary system diseases by Akebia Decne is the result of the interaction of multiple compounds,multiple targets and multiple pathways,which provides a theoretical basis for the further experimental verification. 2021 Vol. 28 (13): 17-24 [Abstract] ( 47 ) HTML (53 KB)  PDF  (0 KB)  ( 5 ) 25 Research progress of non-motor symptom fluctuation in Parkinson′s disease XIE Jin-jin；KUANG Xiao-xiao； KANG Ting-ting；ZHANG Xue-yan；KONG Fei-meng；YANG Xiao-fan Parkinson′s disease in addition to typical motor symptoms,there are many non-motor symptoms,such as constipation,depression,cognitive dysfunction and so on.Studies in recent years have found that non-motor symptoms also fluctuate,such as anxiety,depression,pain,cognition,etc.And many non-motor symptoms showed variations similar to movement fluctuations.Therefore,in the process of diagnosis and treatment,should not only pay attention to the fluctuation of patients′motor symptoms,but also pay attention to the fluctuation of patients′non-motor symptoms.This article mainly reviews the related studies of non-motor symptom fluctuation. 2021 Vol. 28 (13): 25-28 [Abstract] ( 39 ) HTML (37 KB)  PDF  (0 KB)  ( 8 ) 29 Research progress of Parkinson′s disease complicated with depression XU Feng-hua；LUO Hai-yan Parkinson′s disease(PD)is one of the common neurodegenerative diseases,whose clinical manifestations include motor symptoms and non-motor symptoms.Depression is the most common non-motor symptom in PD patients.Depression can increase the disability rate of PD patients,reduce the quality of life of PD patients,and increase the burden of caregivers.At present,the diagnosis and treatment rate of PD with depression is still low.More than 30 domestic and foreign studies on PD with depression in recent years were included in this paper,and it was found that PD with depression has a complex pathophysiological mechanism.In terms of treatment,both standard antidepressant drugs and non-drug therapy have certain effects,but all kinds of treatments have certain adverse reactions.Therefore,the development of individualized treatment plan is the direction of current research.Based on the existing studies,this paper will review the pathogenesis,pathogenesis and treatment of Parkinson′s disease with depression,in order to provide supporting evidence for the prevention and treatment of Parkinson′s disease with depression. 2021 Vol. 28 (13): 29-32 [Abstract] ( 49 ) HTML (39 KB)  PDF  (0 KB)  ( 4 ) 33 Treatment progress in internal fixation of acetabular fractures involving the quadrilateral plate ZHOU Run-tao；GAO Shi-chang Acetabular fracture is a serious injury in clinics,which often involves the quadrilateral plate.The quadrilateral plate refers to the medial wall of the acetabulum,which prevents the medial migration of the femoral head.Acetabular fractures involving the quadrilateral plate are intra-articular fractures,requiring open reduction and internal fixation to anatomically restore the joint surface and avoid the traumatic arthritis.Due to the deep location,minimal bone stock,complicated anatomical structures around the quadrilateral plate and the varied fracture types,the open reduction and internal fixation of acetabular fractures involving the quadrilateral plate is challenging.This article reviews the anatomical characteristics,surgical approaches and internal fixation of the acetabular fracture involving the quadrilateral plate to provide a reference for the clinical treatment. 2021 Vol. 28 (13): 33-37-41 [Abstract] ( 47 ) HTML (51 KB)  PDF  (0 KB)  ( 7 ) 38 Expression and clinical significance of cyclooxygenase-2 in Hashimoto′s thyroiditis complicated with papillary thyroid carcinoma DU Jia-wei Objective To explore the expression and clinical significance of cyclooxygenase-2(COX-2)in Hashimoto′s thyroiditis(HT)combined with papillary thyroid carcinoma(PTC),in order to provide guidance for clinical diagnosis and treatment.Methods The paraffin specimens of 85 patients with HT and PTC in the Department of Pathology of Bengang General Hospital of Liaoning Health Industry Group from July 2019 to July 2020 were collected to detected the expression of COX-2.The positive expression rates of COX-2 in cancer tissues and adjacent tissues were compared,the clinical data of the patients were analyzed,the positive expression rate of COX-2 in cancer tissues of patients with different pathological characteristics [tumor number,tumor diameter,TNM stage,capsule invasion,lymph node metastasis(LNM)]were compared.Results The positive expression rate of COX-2 in cancer tissues of patients with HT combined with PTC was higher than that in adjacent tissues,the difference was significant statistically(P＜0.05).The positive expression rate of COX-2 in HT and PTC patients with capsule invasion was higher than that in patients without capsule invasion,the positive expression rate of COX-2 in HT patients with PTC and LNM was higher than that in patients without LNM,the differences were statistically significant(P＜0.05).There was no significant difference between the positive expression rate of COX-2 in cancer tissues of different tumor number,tumor diameter,TNM stage(P ＞0.05).Logistic regression analysis showed that the positive expression of COX-2 might be the influencing factor of capsule invasion and LNM in HT patients with PTC(OR＞1,P＜0.05).Conclusion The abnormally high expression of COX-2 is closely related to the disease development of HT combined with PTC,which may indicate the occurrence of LNM and capsule invasion.The severity of HT combined with PTC can be predicted based on the expression of COX-2. 2021 Vol. 28 (13): 38-41 [Abstract] ( 40 ) HTML (31 KB)  PDF  (0 KB)  ( 6 ) 42 Study on the correlation between the expression of NRP-2 and the clinicopathological characteristics and prognosis of gastric cancer GAO Yan-hua Objective To observe the clinicopathological characteristics,prognosis and neuropilin-2(NRP-2)expression of gastric cancer patients,and to analyze the relationship between NRP-2 expression and clinicopathological characteristics and prognosis of gastric cancer patients.Methods A total of 120 gastric cancer patients who were admitted to Liaoyang Central Hospital from June 2016 to December 2017 were selected as research objects.All patients were treated with radical gastric cancer surgery.The clinicopathological characteristics and prognosis of the patients were recorded.The predictive value of serum NRP-2 level for different clinicopathological characteristics and prognosis of gastric cancer was observed.Results Among all 120 patients with gastric cancer,38 patients had lower stomach cancer,55 patients had serous and extraserous infiltration,88 patients had lymph node metastasis,and 57 patients had TNM stage Ⅲ.There were 49 cases of recurrence,and the recurrence rate was 40.83%.There were no statistically significant difference in serum NRP-2 levels between different disease sites and TNM stages(P>0.05).The serum NRP-2 level of the patients who had serosal and extraserous infiltration,lymph node metastasis,postoperative recurrence were higher than those of patients who had mucosa and submucosa+muscular layer,no lymph node metastasis,and no recurrence,the differences were statistically significant(P＜0.05).The receiver operating characteristic(ROC)curve results showed that the serum NRP-2 level predicted in patients with gastric cancer,the area under curve(AUC)of serosal and extraserous,lymph node metastasis,and recurrence risk are all>0.80,and the predictive value was ideal.Conclusion NRP-2 may be involved in the occurrence and progression of gastric cancer,and is related to the malignant biological behavior of gastric cancer,and the high expression of NRP-2 can lead to poor prognosis of gastric cancer. 2021 Vol. 28 (13): 42-45 [Abstract] ( 41 ) HTML (32 KB)  PDF  (0 KB)  ( 7 ) 46 Efficacy study of functional electrical stimulation synchronous lower limb rehabilitation robot on ankle function in patients with foot droop after cerebral apoplexy LIU Yan-ping；LIN Qian；CHEN Deng-zhong；LI Zhong-yuan；MA Qi-shou；YANG Huang Objective To explore the clinical effect of functional electrical stimulation(FES)synchronous Lokomat lower limb rehabilitation robot on ankle function in patients with foot droop after cerebral apoplexy.Methods A total of 40 patients with stroke admitted to the Rehabilitation Hospital Affiliated to Fujian University of Traditional Chinese Medicine from September 2017 to August 2019 were selected as the research objects,and they were divided into control group(n=20)and experimental group(n=20)by random number table method.Patients in the control group received FES synchronous artificial assisted walking training,and patients in the experimental group received FES synchronous Lokomat lower limb rehabilitation robot assisted walking training.Before treatment and 4 weeks after treatment,the integrated electromyography(iEMG),the EMG co-contraction ratio(CR)of the ankle-dorsal extensor tibialis anterior muscle and ankle-plantar flexor gastrocnemius muscle,composite spasticity scale(CSS),functional ambulation category(FAC),and 10 meter maximum walking speed(10MWT)were compared between the two groups.Results Before treatment,there were no significant differences in iEMG of ankle-dorsal extensor tibialis anterior muscle,iEMG of ankleplantar flexor gastrocnemius muscle,CR of ankle-dorsal extensor antagonist muscle,CR of ankle-plantar flexor gastrocnemius muscle,CSS score,FAC score and 10MWT between the two groups(P＞0.05).After treatment,the iEMG of ankle-dorsal extensor tibialis anterior muscle,iEMG of ankle-plantar flexor gastrocnemius muscle,FAC scores in the two groups were higher than those before treatment,with statistical significances(P＜0.05).After treatment,the CR of ankle-dorsal extensor antagonist muscle in the two groups were higher than those before treatment,CR of ankle-plantar flexor gastrocnemius muscle and CSS scores in the two groups were lower than those before treatment,10MWT in the two groups were all higher than those before treatment,with statistically significant differences(P＜0.05).After treatment,the iEMG of ankle-dorsal extensor tibialis anterior muscle,iEMG of ankle-plantar flexor gastrocnemius muscle,FAC scores in the experimental group were all higher than those in control group,and 10MWT in the experimental group was higher than that in control group,with statistically significant differences(P＜0.05).After treatment,the CR of ankle-dorsal extensor antagonist muscle in the two groups were higher than those before treatment,CR of ankle-plantar flexor gastrocnemius muscle and CSS scores in the experimental group were lower than those in the control group,10MWT in the experimental group was higher than that in the control group,with statistically significant differences(P＜0.05).Conclusion FES synchronous Lokomat lower limb rehabilitation robot assisted walking training,can significantly improve the ankle function and walking ability of patients with foot droop after cerebral apoplexy. 2021 Vol. 28 (13): 46-50 [Abstract] ( 46 ) HTML (44 KB)  PDF  (0 KB)  ( 8 ) 51 Clinical study of ultrasound-guided Mammotome minimally invasive atherectomy in the treatment of patients with palpable negative breast masses XIE Zi-jian；HUANG Yan；LIU Jin-ping；LI Xiang-ping；LIU Xiao-juan Objective To investigate and analyze the actual effect of ultrasound-guided Mammotome minimally invasive atherectomy in the clinical treatment of patients with palpable negative breast masses.Methods From January to December 2019,a total of 60 patients with palpable negative breast masses admitted to the General Surgery Department of Jiangxi Province Pingxiang Maternity and Child Care Hospital were selected as the research objects,and they were divided into the control group and the observation group by random number table method,with 30 cases in each group.The control group was treated with conventional open resection,and the observation group was treated with ultrasoundguided Mammotome minimally invasive atherectomy.The operation time,intraoperative blood loss,6 months postoperative recurrence and complications,and aesthetic satisfaction of the two groups of patients under different treatment methods were compared.Results The operation time of the observation group was shorter than that of the control group,the intraoperative blood loss was less than that of the control group,the incision healing time was shorter than that of the control group,and the scar length was shorter than that of the control group,the differences were statistically significant(P＜0.05);the total incidence of post-complications was lower than that of the control group,and the difference was statistically significant(P＜0.05);the breast aesthetic satisfaction score of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).Conclusion Ultrasound-guided Mammotome minimally invasive atherectomy can further shorten the operation time of patients with palpable negative breast masses,reduce postoperative complications,reduce the area of scars,and has a good prognosis.Patients are highly satisfied with the appearance and are worthy of clinical application. 2021 Vol. 28 (13): 51-53 [Abstract] ( 51 ) HTML (30 KB)  PDF  (0 KB)  ( 7 ) 54 Therapeutic effect of prophylactic radiotherapy in para-aortic lymphatic drainage area for middle and advanced cervical cancer with positive pelvic lymph nodes WANG Ya-nan；ZENG Si-yuan；ZHONG Mei-ling；YUAN Jian-hui Objective To investigate the effect of prophylaxis radiotherapy in para-aortic lymphatic drainage area on middle and advanced cervical cancer with positive pelvic lymph nodes.Methods A total of 81 patients with advanced cervical cancer with pelvic lymph node positive admitted to Jiangxi maternal and child health hospital from February 2015 to October 2017 were selected as the research subjects.According to random number table method,they were divided into control group(40 cases)and study group(41 cases).The control group received platinum-based chemotherapy,and the study group received prophylactic radiotherapy in the para-aortic lymphatic drainage area on this basis.The disease control rate,the incidence of adverse reactions of acute radiotherapy and chemotherapy and the survival rate were compared between two groups.Results The disease control rate in the study group was higher than that in the control group,and the difference was statistically significant(P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P＞0.05).The 2- and 3-year cumulative survival rate in the study group were higher than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion In the clinical treatment of middle and advanced cervical cancer complicated with positive pelvic lymph nodes,prophylactic radiotherapy in the para-aortic lymphatic drainage area has good clinical efficacy and high safety,which is worthy of promotion. 2021 Vol. 28 (13): 54-56-60 [Abstract] ( 45 ) HTML (32 KB)  PDF  (0 KB)  ( 6 ) 57 Clinical study on the treatment of type A3 thoracolumbar fracture in the elderly by Wiltse approach combined with internal fixation of the injured vertebra with screws CHEN Wei；QIU Hai-tao；PAN Qi-lin；CHEN Qin；LI Qiao-xin1 XU Li-mei Objective To explore the clinical effect of Wiltse approach combined with internal fixation of the injured vertebra with screws in treatment of type A3 thoracolumbar fracture in the elderly.Methods A total of 78 elderly patients with type A3 thoracolumbar fractures admitted to Quannan People′s Hospital and Ganzhou People′s Hospital of Jiangxi Province from June 2018 to June 2019 were selected as the research objects,and they were divided into control group(39 cases)and study group(39 cases)according to the random number table method.The control group was treated with internal fixation of vertebral screw through the traditional surgical approach,and the study group was treated with internal fixation of vertebral screw through the Wiltse approach.The operative time,intraoperative hemorrhage,postoperative drainage and postoperative complications were compared between the two groups.The pain score(visual analogue scale [VAS]),Oswestry disability index(ODI)and kyphosis Cobb angle were compared between the two groups at before operation,1 month after operation,6 months after operation and 12 months after operation.Results The operation time of the study group was shorter than that of the control group,intraoperative hemorrhage and postoperative drainage were less than those in the control group,the differences were statistically significant(P＜0.05).There were no significant differences in VAS scores,ODI scores and kyphosis Cobb angle between the two groups at before operation(P＞0.05),but the VAS scores,ODI scores and kyphosis Cobb angle of the study group were lower than those of the control group at 1 month,6 months and 12 months after operation,the differences were statistically significant(P ＜0.05).There was no significant difference in the incidence of complications between the two groups(P＞0.05).Conclusion Wiltse approach combined with internal fixation of the injured vertebra with screws is effective in the treatment of type A3 thoracolumbar fractures in the elderly,with less intraoperative hemorrhage,less postoperative pain and faster postoperative recovery. 2021 Vol. 28 (13): 57-60 [Abstract] ( 45 ) HTML (35 KB)  PDF  (0 KB)  ( 5 ) 61 Clinical study on the correlation between the hemodynamic changes of superior mesenteric artery and ascites due to cirrhosis LIU Rong；CHEN Qing；XIONG Mei-e Objective To investigate the relationship between the hemodynamic changes of superior mesenteric artery(SMA)and ascites due to cirrhosis.Methods Thirty patients with liver cirrhosis and ascites admitted to the Second People′s Hospital of Pingxiang City,Jiangxi Province from November 2018 to November 2020 were selected as the observation group,and 30 patients who underwent physical examination in the Second People′s Hospital of Pingxiang City,Jiangxi Province during the same period were selected as the control group.Both groups of subjects used color ultrasound imaging to perform superior mesenteric artery hemodynamic testing,and the observation group received color ultrasound 1 week after the disappearance of ascites after comprehensive treatment.The hemodynamic index levels of superior mesenteric artery which were(SMA)inner diameter,blood flow velocity,blood flow,SMA pulsation index(SMA-PI)and SMA resistance index(SMA-RI)were compared between the healthy group and observation group before and after treatment.Results The inner diameter of the SMA of the observation group was longer than that of the control group,the blood flow was faster than that of the control group,and the blood flow was more than that of the control group,the SMA-PI and SMA-RI of the observation group were lower than those of the control group,the differences were statistically significant(P＜0.05).In the observation group,the inner diameter of the SMA after treatment for ascites resolution was shorter than that at before ascites resolution,blood flow was slower than that at before ascites resolution,blood flow was lower than that at before ascites resolution,and SMA-PI and SMA-RI were higher than those at before ascites resolution,the differences were statistically significant(P＜0.05).Logistic multivariate analysis results showed that SMA inner diameter(β=0.74，OR=1.18，95%CI=1.05-1.97),blood flow velocity(β=1.49，OR=2.04，95%CI=2.01-2.69),blood flow(β=1.26，OR=2.09，95%CI=2.03-2.78),SMA-PI(β=-0.26，OR=0.68，95%CI=0.60-0.83),SMARI(β=-0.31，OR=0.72，95%CI=0.69-0.98)were the influence factors for the formation of ascites due to liver cirrhosis(P＜0.05).Conclusion The superior mesenteric artery hyperdynamic circulation in patients with liver cirrhosis is one of the reasons for the formation of ascites.In order to prevent the occurrence of cirrhotic ascites or improve the prognosis of patients with cirrhotic ascites,it is necessary to improve the hyperdynamic circulation of mesenteric artery blood flow in patients with liver cirrhosis as soon as possible. 2021 Vol. 28 (13): 61-63 [Abstract] ( 41 ) HTML (31 KB)  PDF  (0 KB)  ( 7 ) 64 Clinical effect of Rosuvastatin Calcium Tablets combined with Zhibitai in the treatment of hyperlipidemia TAN Bin； WU Yi-jun；YU Bo Objective To analyze the value of Rosuvastatin Calcium Tablets combined with Zhibitai in the treatment of hyperlipidemia.Methods One hundred and twenty patients with hyperlipidemia treated in the Department of Emergency and Cardiovascular Medicine in the Third People′s Hospital of Jingdezhen City from September 2019 to August 2020 were selected as research subjects,and they were divided into the observation group(n=60)and the control group(n=60)by the random number method.Observation group was treated with Rosuvastatin Calcium Tablets combined with Zhibitai,and control group was treated with Rosuvastatin Calcium Tablets.The levels of total cholesterol(TC),triglyceride(TG),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C)before and after treatment and the total incidence of adverse reactions of the two groups were compared.Results Before treatment,there were no statistical significances in TC,TG,HDL-C and LDL-C between the two groups(P＞0.05).The TC and TG of the two groups after treatment were lower than those before treatment,the differences were statistically significant(P＜0.05).The TC and TG of observation group were lower than those in the control group after treatment,the differences were statistically significant(P＜0.05).The HDL-C of the observation group after treatment was higher than that before treatment,LDL-C of observation group after treatment was lower than that before treatment,the differences were statistically significant(P＜0.05).There were no significant differences in the HDL-C and LDL-C of control group before and after treatment(P＞0.05).The LDL-C level in observation group after treatment was lower than that in the control group,and HDL-C level was higher than that in the control group,with statistical significances(P＜0.05).There was no statistical significance in the total incidence of adverse reactions between the two groups(P＞0.05).Conclusion Rosuvastatin Calcium Tablets combined with Zhibitai in the treatment of hyperlipidemia has a good effect,not only to improve the level of blood lipid,but also contribute to the stability of atherosclerotic plaque,and does not increase adverse reactions,which is worthy of clinical application. 2021 Vol. 28 (13): 64-66 [Abstract] ( 166 ) HTML (31 KB)  PDF  (0 KB)  ( 7 ) 67 Effect of Salmeterol Ticasone Powder Inhaler combined with noninvasive positive pressure ventilation in the treatment of chronic obstructive pulmonary disease complicated with respiratory failure DU Lin；ZHANG Xi-chang Objective To investigate the efficacy and safety of Salmeterol Ticasone Powder Inhaler combined with noninvasive positive pressure ventilation(NPPV)in the treatment of chronic obstructive pulmonary disease(COPD)complicated with respiratory failure.Methods A total of 50 patients with COPD complicated with respiratory failure who were treated in the People′s Hospital in Lvyuan District of Changchun City from December 2018 to December 2019 were selected as the research subjects,and they were divided into study group and control group according to random number table method,with 25 cases in each group.Control group was treated with NPPV on the basis of conventional treatment.Patients in the study group received Salmeterol Ticasone Powder Inhaler combined with NPPV in addition to conventional treatment.The therapeutic effect of the two groups was compared and analyzed.Lung function before and after treatment was compared between the two groups.The total incidence of adverse reactions was compared between the two groups.Results The total effective rate in the study group was higher than that in the control group,and the difference was statistically significant(P＜0.05).Before treatment,there were no significant differences in the forced expiratory volume in the first second(FEV1),the ratio of FEV1 to forced vital capacity(FEV1%),the ratio of forced expiratory volume to forced vital capacity(FEV1/FVC)and the 6 min walk test(6MWT)between the two groups(P＞0.05).After treatment,FEV1,FEV1% and FEV1/FVC in the study group were higher than those in the control group,and 6MWT was longer than that in the control group,with statistically significant differences(P＜0.05).After treatment,the total incidence of adverse reactions in the study group was lower than that in the control group,with statistical significance(P＜0.05).Conclusion The use of Salmeterol Ticasone Powder Inhaler combined with NPPV in the treatment of COPD complicated with respiratory failure has outstanding clinical effect,which can significantly improve the pulmonary function indexes of patients,and significantly reduce the total incidence of clinical adverse reactions in patients after treatment.This program is safe and effective,which is worth promoting. 2021 Vol. 28 (13): 67-70 [Abstract] ( 43 ) HTML (38 KB)  PDF  (0 KB)  ( 6 ) 71 Changes of interleukin-1β and tumor necrosis factor-α in serum of patients with intestinal obstruction before and after operation LI Xin-yuan；DU Fei；GAO Feng；LIU Zi-qiang；LYU Jie；REN Li-fen Objective To observe the changes of interleukin-1β(IL-1β)and tumor necrosis factor-α(TNF-α)in patients with intestinal obstruction treated by operation and to explore the clinical significance.Methods A total of 40 patients with intestinal obstruction who were hospitalized in the First People′s Hospital of Longnan City,Gansu Province from August 2016 to August 2018 were selected as the research objects.According to whether there was intestinal necrosis during the operation,they were divided into two groups: simple intestinal obstruction group(18 cases)and strangulated intestinal obstruction group(22 cases).The fasting peripheral venous blood was collected at the time of admission and 3 and 7 days after the operation,and the serum levels of IL-1β and TNF-α were detected by enzymelinked immunosorbent assay(ELISA).Results The levels of IL-1β between the two groups were compared at the time of admission,3 d after operation,and 7 d after operation,the differences were statistically significant(P＜0.05).The comparison of IL-1β between the simple intestinal obstruction group and the strangulated intestinal obstruction group at each time point was statistically significant(P＜0.05).There was a statistically significant difference in the interaction between group and time in IL-1β(P＜0.05).The levels of TNF-α between the two groups were compared at the time of admission,3 d after operation,and 7 d after operation,the differences were statistically significant(P＜0.05).The comparison of TNF-α between the simple intestinal obstruction group and the strangulated intestinal obstruction group at each time point was statistically significant(P＜0.05).There was a statistically significant difference in the interaction between group and time in TNF-α(P＜0.05).Conclusion Serum IL-1β and TNF-α in patients with intestinal obstruction decrease with the disease progression.Dynamic monitoring of postoperative IL-1β and TNF-α helps to understand the outcome of patients with intestinal obstruction and suggests that they may be intestinal early inflammatory cytokines in strangulation intestinal obstruction. 2021 Vol. 28 (13): 71-73-77 [Abstract] ( 45 ) HTML (33 KB)  PDF  (0 KB)  ( 8 ) 74 Application value and safety of combined sequential enteral nutrition support therapy in patients with mechanical ventilation in ICU JIANG Xiao-ming;LIU Xue-jing;SUN Yu Objective To investigate the application value and safety of combined sequential enteral nutrition support therapy in patients with mechanical ventilation in ICU.Methods A total of eighty cases of severe patients requiring mechanical ventilation who admitted to Beijing Mentougou District Hospital from January 2019 to June 2020 were selected as the research objects,and randomly divided into the control group(40 cases)and the intervention group(40 cases)according to the random drawing method.The control group was treated with enteral nutrition suspension of integrin type,while the intervention group was treated with combined sequential enteral nutrition support of enteral nutrition suspension of short peptide type and enteral nutrition suspension of integrin type.The nutritional indicators(hemoglobin [Hb],serum albumin [ALB],nitrogen balance [NE],upper arm muscle circumference [MAMC]and biceps skin wrinkle thickness [TSF]),recovery effect(nutrition compliance rate,immunoglobulin G [IgG],length of hospital stay)and occurrence of adverse reactions were compared between the two groups.Results After the intervention,the levels of Hb,ALB,MAMC,TSF and other nutritional indicators in the intervention group were higher than those in the control group,with statistically significant differences(P＜0.05);the IgG level and nutritional compliance rate in the intervention group were higher than those in the control group,with statistically significant differences(P＜0.05);the length of hospital stay in the intervention group was shorter than that in the control group,with statistically significant difference(P ＜0.05);the incidence rates of adverse reactions such as reflux,diarrhea and abdominal distension in the intervention group were all lower than those in the control group,with statistically significant differences(P＜0.05).Conclusion In ICU patients with mechanical ventilation,the combined sequential enteral nutrition support therapy of short peptide nutrition solution and whole protein nutrition solution has a significant effect,which can improve their nutritional levels,reduce adverse reactions,promote patients′recovery and shorten the length of hospital stay,has high safety,and is worthy of popularization and application. 2021 Vol. 28 (13): 74-77 [Abstract] ( 49 ) HTML (33 KB)  PDF  (0 KB)  ( 7 ) 78 Clinical effect of neuroendoscopy combined with postoperative controlled drainage in the treatment of intracerebral hematoma HUANG Min-dong；JIANG Nan；ZOU Jian-dan Objective To investigate the clinical effect of neuroendoscopy combined with postoperative controlled drainage in the treatment of intracerebral hematoma.Methods A total of 40 patients with intracerebral hematoma admitted to Jieyang People′s Hospital from January 2017 to June 2020 were selected and divided into experimental group and control group according to the random number table method with 20 cases in each group.The experimental group were treated with neuroendoscopic intracerebral hematoma clearance,and postoperative drainage tube was used with controlled drainage.The control group were treated with drilling puncture and drainage of intracerebral hematoma.After the operation,the hematoma clearance rate,drainage tube indwelling time,postoperative urokinase ratio,glasgow outcome scale(GOS)score and whether there was excessive drainage were compared between the two groups.Results The hematoma clearance rate of the experimental group was higher than that of the control group,the difference was statistically significant(P＜0.05).The indwelling time of drainage tube in the experimental group was shorter than that in the control group,the difference was statistically significant(P＜0.05).The ratio of urokinase in the experimental group was lower than that in the control group,the difference was statistically significant(P＜0.05).GOS score of the experimental group was higher than that of the control group,the difference was statistically significant(P＜0.05).The incidence of excessive drainage in the control group was higher than that in the experimental group,the difference was statistically significant(P＜0.05).Conclusion The clinical effect of neuroendoscopy in the treatment of intracerebral hematoma is better than that of drilling and drainage of hematoma. 2021 Vol. 28 (13): 78-81 [Abstract] ( 39 ) HTML (36 KB)  PDF  (0 KB)  ( 8 ) 82 Stereotactic brain surgery for refractory psychosis ZHONG Wu-zhao；LUO Yun-hui；LIU Fei-long；YANG Qi-fan Objective To explore the effect of stereotactic brain surgery in the treatment of refractory psychosis.Methods A total of 60 patients with refractory mental illness who were treated in Nanchang 334 Hospital from October 2017 to November 2019 were selected as the research subjects.They were divided into the control group and the observation group according to random number table method,with 30 cases in each group.Patients in the control group received non-surgical treatment,and patients in the observation group received stereotactic brain surgery.The dose of clozapine,functional independence measure(FIM)score,gross motor function scale-88(GMFM-88)score,gross motor function scale(GMFCS)score,and Glasgow outcome scale(GOS)classification were compared.Results After six months of treatment,the average daily dose of clozapine in the observation group was lower than that of the control group,and the difference was statistically significant(P＜0.05).After six months of treatment,the FIM,GMFM-88,and GMFCS scores were all higher than before treatment in the two groups,and the FIM,GMFM-88,and GMFCS scores of the observation group were higher than those of the control group,and the differences were statistically significant(P＜0.05).After six months of treatment,the GOS classification of the observation group was better than that of the control group with statistical significance(P＜0.05).Conclusion Patients with refractory psychosis can be treated with stereotactic brain surgery,which can reduce the use of psychotropic drugs,and is conducive to the recovery of patient′s neurological function in a favorable prognosis. 2021 Vol. 28 (13): 82-84 [Abstract] ( 41 ) HTML (31 KB)  PDF  (0 KB)  ( 8 ) 85 Clinical study on the relationship between the monocyte/high-density lipoprotein cholesterol ratio and the prognosis of patients initially diagnosed with cerebral arterial thrombosis SU Yu-rong；LI Zhi-yong；LI Huan-sheng；YAN Guo-ping；ZHOU Cong-bin；WU Wen-xun Objective To explore the relationship between the monocyte/high-density lipoprotein cholesterol ratio(MHR)and the prognosis of patients initially diagnosed with cerebral arterial thrombosis.Methods A total of 120 patients with cerebral arterial thrombosis admitted to General Hospital of Pingxiang Mining Group Co.,Ltd.from July 2018 to December 2019 were selected and divided into a good group(60 cases)and a poor group(60 cases)according to the prognosis of the patients during the half-year follow-up.The basic information of the two groups of patients was collected.Routine blood tests and blood lipid tests were carried out,and their MHR was calculated.The basic information and clinical indicators of the two groups were compared,and the relationship between MHR and the prognosis of patients with cerebral arterial thrombosis was analyzed,and the value of MHR in predicting the poor prognosis of patients with cerebral arterial thrombosis.Divide 120 patients into two groups according to the ROC curve for predicting the poor prognosis of patients with cerebral arterial thrombosis was the best value,and compare their prognosis.Results The national institute of health stroke scale(NIHSS)score and MHR values of the good group were lower than those of the poor group,the number of monocytes of the good group was less than that of the poor group,and the high density lipoprotein cholesterol(HDL-C)of the good group was higherr than that of the poor group,the differences were statistically significant(P＜0.05).Age(β=-0.420,OR=1.04,95%CI=1.02-1.08),NIHSS score(β=-0.451,OR=1.32,95%CI=1.18-1.45),MHR(β=-0.562,OR= 2.38,95%CI=1.11-5.24)were the main prognostic factors of the patients with cerebral arterial thrombosis.The area under the ROC curve of MHR predicting poor prognosis of ischemic stroke was 0.694(95%CI=0.636-0.748,P＜0.05),the sensitivity and specificity were 79.41% and 58.33%,and the best cutoff value was 0.48.The recurrence rate and mortality of patients in the MHR＞0.48 group were higher than those in the MHR≤0.48 group,and the differences were statistically significant(P＜0.05).Conclusion The higher the MHR value,the more severe the nerve damage in patients initially diagnosed with ischemic stroke and the worse the prognosis. 2021 Vol. 28 (13): 85-88 [Abstract] ( 44 ) HTML (37 KB)  PDF  (0 KB)  ( 9 ) 89 Effect of Quetiapine combined with Lithium Carbonate on inflammatory response and manic symptoms in patients with bipolar disorder HUANG Chang-rong；LIU Wang-lin；MA Xiao-mian；HE Zhu-fa Objective To observe the effect of quetiapine combined with lithium carbonate on inflammatory response and manic symptoms in patients with bipolar disorder.Methods A total of 78 patients with bipolar disorder admitted to Ganzhou Third People′s Hospital from September 2017 to August 2019 were selected and divided into the observation group(39 cases)and the control group(39 cases)according to the random number table method.The control group received Lithium Carbonate treatment,and the observation group received Quetiapine combined with Lithium Carbonate treatment.The inflammatory response indicators(tumor necrosis factor-α [TNF-α],interleukin-1 [IL-1],interleukin-10[IL-10]),manic symptoms and adverse reactions were compared between the two groups.Results There were no statistically significant differences in the levels of TNF-α,IL-1,IL-10 and BRMS scores between the two groups before treatment(P＞0.05).After treatment,the level of TNF-α and IL-1,and the BRMS score of the observation group were lower than those of the control group,and the level of IL-10 of the observation group was higher than that of the control group,the differences were statistically significant(P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P＞0.05).Conclusion The combination of Quetiapine and Lithium Carbonate in the treatment of bipolar disorder can help control the condition,relieve manic symptoms and inflammation,and is safe for clinical application. 2021 Vol. 28 (13): 89-91 [Abstract] ( 49 ) HTML (31 KB)  PDF  (0 KB)  ( 6 ) 92 Clinical effect of Lecithin Tablets in the treatment of Alzheimer′s disease LIU Zheng;LIU Bo-wen Objective To evaluate the efficacy of Lecithin Tablets in the treatment of mild and moderate Alzheimer′s disease(AD).Methods A total of 118 patients with mild to moderate AD admitted to the First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine from January 2019 to January 2020 were selected and divided into observation group and control group according to the random number table method,with 59 cases in each group.The control group received conventional treatment,and the observation group received Lecithin Tablets treatment on the basis of the control group.Both groups received continuous medication for 12 weeks.The clinical efficacy of the two groups was observed and compared,the clinical memory scale was used to evaluate and compare the memory scores of the two groups,the ability of daily living(ADL)was used to assess and compare the ability of daily living of the two groups,and the dementia deficit scale(ADS)was used to evaluate and compare the two Group dementia degree,observe and compare the occurrence of adverse reactions between the two groups.Results The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).Before treatment,there was no significant difference in the scores of the clinical memory scales between the two groups(P＞0.05);after 12 weeks of treatment,the clinical memory scale scores of the observation group were higher than those before the treatment,the differences were statistically significant(P＜0.05).After 6 and 12 weeks of treatment,the ADL and ADS scores of the two groups were lower than those of before treatment,and the observation group was lower than that of the control group in the same period,the differences were statistically significant(P＜0.05).There were no abnormal findings in the laboratory liver and kidney functions and the three major routine examinations before and after treatment in the two groups.Conclusion It had certain clinical effect on Lecithin Tablets in the treatment of mild and moderate AD,and the clinical memory scale,ADL and ADS scores have been effectively improved,which has certain security. 2021 Vol. 28 (13): 92-95 [Abstract] ( 41 ) HTML (36 KB)  PDF  (0 KB)  ( 7 ) 96 Effect of rTMS stimulation of different brain regions combined with Paroxetine in treatment of obsessive-compulsive disorder ZHENG Yu-ling;WANG Zhen-yan Objective To explore the clinical effect of rTMS stimulation of different brain regions combined with Paroxetine in treatment of obsessive-compulsive disorder.Methods A total of 78 cases of patients with obsessive-compulsive disorder admitted to Shangrao Third People′s Hospital from January 2018 to December 2019 were selected as the research objects,and divided into the observation group and the control group according to the random number table method,with 39 cases in each group.The observation group treated with rTMS stimulation of right prefrontal lobe and bilateral auxiliary motor area combined with Paroxetine,and the control group treated with rTMS stimulation of right prefrontal lobe combined with Paroxetine.The Yale-Brown Obsessive Compulsive Scale(Y-BOCS)score,Hamilton Depression Scale(HAMD)score,Hamilton Anxiety Scale(HAMA)score,total incidence of adverse reactions and clinical effect were compared between the two groups.Results After treatment,the Y-BOCS score,HAMD score and HAMA score in the observation group were lower than those in the control group,the difference was statistically significant(P＜0.01).After treatment,the total effective rate of treatment in the observation group was higher than that in the control group,the difference was statistically significant(P＜0.01).And the total incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.01).Conclusion In clinical treatment of patients with obsessive-compulsive disorder,the rTMS stimulation of multiple brain regions combined with Paroxetine treatment will be more conducive to improve the treatment effect of patients.It is worth clinical application than stimulating the right prefrontal lobe alone,and worthy of clinical application. 2021 Vol. 28 (13): 96-98 [Abstract] ( 41 ) HTML (30 KB)  PDF  (0 KB)  ( 4 ) 99 Application effects of nucleus accumbens combined with anterior limb of internal capsule as the target of deep brain stimulation in the treatment of refractory obsessive-compulsive disorder HE Jun-yan Objective To explore the application effects of nucleus accumbens combined with anterior limb of internal capsule as the target of deep brain stimulation in the treatment of refractory obsessive-compulsive disorder.Methods A total of 60 patients with refractory obsessive-compulsive disorder admitted to Kangning Hospital of Jinzhou City from July 2017 to July 2018 were selected as the control group,and a total of 58 patients with refractory obsessive-compulsive disorder admitted to Kangning Hospital of Jinzhou City from August 2018 to August 2019 were selected as the observation group.The control group treated with anterior limb of internal capsule as the target of deep brain stimulation,and the observation group treated with nucleus accumbens combined with anterior limb of internal capsule as the target of deep brain stimulation.The improvement of symptoms and the mental states of patients were compared between the two groups,and the recurrence was counted within 6 months after treatment.Results Six months after treatment,the Yale-Brown Obsessive Compulsive Scale(Y-BOCS)score of the observation group were lower than that of the control group,the difference was statistically significant(P＜0.05).Six months after treatment,the Hamilton Anxiety Scale(HAMA)score,Hamilton Depression Scale(HAMD)score,and Symptom Check list 90(SCL-90)scores of the observation group were lower than those of the control group,the differences were statistically significant(P＜0.05).Six months after treatment,the total recurrence rate of the observation group was lower than that of the control group,and the difference was statistically significant(P＜0.05).Conclusion Nucleus accumbens combined with anterior limb of internal capsule as the target of deep brain stimulation for refractory obsessive-compulsive disorder can not only improve the compulsive behaviors,but also effectively reduce the recurrence rate of symptoms. 2021 Vol. 28 (13): 99-101-105 [Abstract] ( 35 ) HTML (32 KB)  PDF  (0 KB)  ( 6 ) 102 Clinical effects of intrathecal injection and intravenous drip of antibiotics in the treatment of secondary intracranial infection after severe craniocerebral injury LYU Zhi-gui;LIN Xian-jie Objective To investigate the clinical efficacy of intrathecal injection and intravenous drip of antibiotics in the treatment of secondary intracranial infection after severe craniocerebral injury.Methods A total of 120 patients with severe craniocerebral injury secondary intracranial infection admitted to Zhongshan Torch Development Zone Hospital were selected as the research objects.They were divided into observation group and control group by random number table method,with 60 cases in each group.The control group was given systemic intravenous drip of vancomycin and meropenem on the basis of conventional treatment,while the observation group was given intrathecal injection of vancomycin and meropenem on the basis of conventional treatment.The clinical therapeutic effect,prognosis and safety of the two groups were compared.Results The total effective rate of the observation group was higher than that of the control group,the time of fever reduction,white blood cell return to normal and cure time were shorter than that of the control group,and the total cost of treatment was lower than that of the control group,the differences were statistically significant(P＜0.05).Before treatment,there were no significant differences in the indexes of high mobility group protein-1(HMGB-1)and receptor for advanced glycation end products(RAGE)in cerebrospinal fluid of the two groups(P＞0.05),the HMGB-1 and RAGE indexes of the observation group were lower than those of the control group after 7 days of treatment,the differences were statistically significant(P＜0.05).The incidence of adverse reactions and sequelae in observation group was lower than that in control group,and the difference was statistically significant(P＜0.05).Conclusion Intrasheath injection of antibiotics in the treatment of intracranial infection secondary to severe craniocerebral injury can effectively and quickly control the patient′s infection condition,with more significant clinical efficacy and lower risk of adverse reactions and sequelae after treatment,which has clinical application and promotion value. 2021 Vol. 28 (13): 102-105 [Abstract] ( 41 ) HTML (35 KB)  PDF  (0 KB)  ( 7 ) 106 Efficacy analysis of TUCBDP combined with TURP in the treatment of prostate with more than 1 cm protruding bladder KONG Min;CHEN Jun;YUAN Wu-liang Objective To investigate the effect of transurethral columnar balloon dilation of the prostate(TUCBDP)combined with transurethral resection of prostate(TURP)in the treatment of intravesical protrusion with over 1 cm of hyperplasia of prostate.Methods A total of 40 patients with intravesical protrusion with over 1 cm of prostatic hyperplasia admitted to the First Affiliated Hospital of Jiangxi Medical College from August 2018 to August 2020 were selected as the research subjects,they were divided into the experimental group and the control group according to the overall stratified grouping randomization method,with 20 cases in each group.The control group was treated with TURP,and the test group was treated with TUCBDP combined with TURP.After 6 months of continuous follow-up,the scores of the international prostate symptom scale(IPSS),the quality of life(QOL)assessment scale and the maximum urine flow rate(MFR)were recorded between the two groups.Results The IPSS scores of the two groups after operation were lower than those before operation,the QOL scores of the two groups after operation were higher than those before operation,and the IPSS score of the experimental group after operation was lower than that of the control group,and the QOL score of the experimental group after operation was higher than that of the control group,the differences were statistically significant(P＜0.05).The MFR of the two groups at 1 month after operation were higher than those before operation,and the MFR of the experimental group at 1 month after operation was higher than that of the control group,the differences were statistically significant(P＜0.05).Conclusion TUCBDP combined with TURP in the treatment of intravesical protrusion with over 1 cm of prostatic hyperplasia can effectively improve the symptom relief of patients,and improve their MFR and quality of life. 2021 Vol. 28 (13): 106-108 [Abstract] ( 39 ) HTML (30 KB)  PDF  (0 KB)  ( 6 ) 109 Effect comparison of Leflunomide and Cyclophosphamide in the treatment of lupus nephritis TAN Jing Objective To compare the effect of Leflunomide and Cyclophosphamide in the treatment of lupus nephritis.Methods A total of 72 patients with lupus nephritis admitted to Iron Coal General Hospital of Liaoning Health Industry Group from January to December 2019 were selected as the research objects.They were divided into the control group(36 cases)and the observation group(36 cases)according to simple randomization method.The control group was treated with Cyclophosphamide,and the observation group was treated with Leflunomide.The laboratory-related indicators,systemic lupus erythematosus disease activity(SLEDAI)score,clinical efficacy,and drug safety were compared between the two groups.Results The levels of serum creatinine(SCr),blood urea nitrogen(BUN),cystatin-C(Cys-C),24 h urine protein quantitative(24 h Upr),SLEDAI score and the total incidence of adverse reactions of the observation group after treatment were lower than those of the control group,the differences were statistically significant(P＜0.05).The disease remission rate of the observation group was higher than that of the control group,the difference was statistically significant(P＜0.05).Conclusion Leflunomide is effective and safe in the treatment of patients with lupus nephritis. 2021 Vol. 28 (13): 109-111 [Abstract] ( 49 ) HTML (30 KB)  PDF  (0 KB)  ( 6 ) 112 Influence of transurethral columnar balloon dilation of prostate on urethral function and sexual function in patients with benign prostatic hyperplasia ZHANG Si-zhou；XU Shi-tian；PAN Jun-cheng；HUANG Xiao-long Objective To explore the influence of transurethral columnar balloon dilation of prostate on urethral function and sexual function in patients with benign prostatic hyperplasia.Methods A total of 96 elderly patients with benign prostatic hyperplasia admitted to the Department of Urology of People′s Hospital of Hechuan District in Chongqing City from May 2017 to July 2019 were selected and divided into the control group(n=48)and the observation group(n=48)according to random number table method.The control group was treated with transurethral plasmakinetic resection of prostate,and the observation group was treated with transurethral columnar balloon dilation of prostate.The operation time,intraoperative blood loss,hospitalization time,postoperative indwelling catheter time,continuous bladder irrigation time,residual urine volume(RUV),maximum urinary flow rate(Qmax),quality of life(QOL)score,international prostate symptom score(IPSS),international erectile function index(IIEF-5)and sexual function improvement were compared between the two groups.Results The operation time,hospitalization time,indwelling catheter time and continuous bladder irrigation time in the observation group were shorter than those in the control group,and the amount of bleeding during operation in the observation group was less than that in the control group,and the differences were statistically significant(P＜0.05).The RUV,QOL and IPSS scores of the two groups after operation were lower than those before operation,and the Qmax of the two groups after operation was higher than that before operation(P＜0.05).There were no significant differences in IPSS,QOL,RUV and Qmax between the two groups after operation(P＞0.05).The IIEF-5 score of the observation group after operation was better than that of the control group,and the incidence rates of erectile rigidity,sexual dysfunction and retrograde ejaculation of the observation group after operation were lower than those of the control group(P＜0.05).Conclusion Transurethral columnar balloon dilation of prostate can improve the therapeutic effect of patients with benign prostatic hyperplasia,with less damage and quicker recovery.It is helpful for retention of male sexual function,and improve the patients quality of life,so it can be used for a better choice in the trement of patients with benign prostatic hyperplasia. 2021 Vol. 28 (13): 112-115 [Abstract] ( 30 ) HTML (40 KB)  PDF  (0 KB)  ( 6 ) 116 Effect and safety of Levocarnitine combined with hemodialysis in the treatment of chronic renal failure ZHOU Yuan Objective To analyze the effect and safety of Levocarnitine combined with hemodialysis in the treatment of chronic renal failure.Methods A total of 100 patients with chronic renal failure admitted to Songzi People′s Hospital from January 2019 to January 2020 were selected as the research objects,and they were divided into the control group(50 cases)and the observation group(50 cases)using a random number table method.The control group was treated with hemodialysis,and the observation group was treated with Levocarnitine combined with hemodialysis.The clinical treatment effect,plasma indexes before and after treatment and the total incidence of complications were compared between the two groups.Results The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).The levels of plasma indexes such as tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),and C-reactive protein were lower than those of the control group,and the differences were statistically significant(P ＜0.05).There was no significant difference in the total incidence of complications between the two groups(P＞0.05).Conclusion The treatment of patients with chronic renal failure with Levocarnitine combined with hemodialys can effectively enhance the patient′s renal function,improve plasma indicators,and has high safety.The clinical treatment effect is good,and it is worthy of clinical promotion and application. 2021 Vol. 28 (13): 116-118 [Abstract] ( 40 ) HTML (28 KB)  PDF  (0 KB)  ( 7 ) 119 Effect of Dapagliflozin on neutrophil to lymphocyte ratio,platelet to lymphocyte ratio,C-reactive protein and interleukin 6 in type 2 diabetes mellitus patients with carotid atherosclerosis ZHANG Yao-yi；TIAN Chen-guang Objective To investigate the effect of Dapagliflozin on the neutrophil to lymphocyte ratio(NLR),platelet to lymphocyte ratio(PLR),C-reactive protein(CRP)and interleukin 6(IL-6)in patients with type 2 diabetes mellitus(T2DM)with carotid atherosclerosis.Methods A total of 100 patients with T2DM complicated with atherosclerosis admitted to the Second Affiliated Hospital of Zhengzhou University from August 2019 to January 2020 were selected as the research objects.They were divided into Dap group and Con group according to the random number method,with 50 cases in each group.The patients in the Con group were treated with proglycemic regimen,and the patients in the Dap group were treated with Dapagliflozin in addition to proglycemic regimen for 20 weeks.The levels of NLR,PLR,CRP and IL-6 in the two groups before and after treatment were compared.Results Before treatment,there were no significant differences in the levels of NLR,PLR,CRP and IL-6 between the two groups(P＞0.05).After treatment,the levels of NLR,PLR,CRP and IL-6 in the two groups were lower than those before treatment,and the differences were statistically significant(P＜0.05).After treatment,the levels of NLR,PLR,CRP and IL-6 in Dap group were lower than those in Con group,and the differences were statistically significant(P＜0.05).Conclusion Dapagliflozin can reduce NLR,PLR,CRP and IL-6 levels in patients with T2DM and arteriosclerosis,and improve the body′s low inflammatory state. 2021 Vol. 28 (13): 119-122 [Abstract] ( 52 ) HTML (32 KB)  PDF  (0 KB)  ( 7 ) 123 Intervention effect of "Internet plus" technology optimized medical care model on elderly diabetic patients GUO Yan-qing；CHEN Si-ping；PENG Fang-yi Objective To explore the intervention effect of "Internet plus" technology optimized medical care model on elderly diabetic patients.Methods One hundred patients with diabetes mellitus in Pingxiang Huayuan Community and Jiangwan Community from May 2019 to August 2019 were selected as research subjects,and were divided into the control group(n=50)and the observation group(n=50)according to the odd and even number grouping method.Routine medical care combined with old-age care model was given to the control group,and "Internet plus" optimized medical care model was given to the observation group.The fasting blood glucose(FPG),blood glucose 2 h after breakfast(2 h PG)and glycosylated hemoglobin(HbA1c)in the two groups before intervention and 3,6 months after intervention were compared.The incidence of hypoglycemia was compared between the two groups after 6 months of intervention.The scores of self-management behavior after 6 months of intervention were compared between the two groups.Results There were no statistically significant differences in FPG,2 h PG or HbA1c between the two groups before the intervention(P＞0.05).The levels of FPG,2 h PG and HbA1c at 3 months after the intervention in the observation group were lower than those in the control group,with statically significant differences(P＜0.05).The levels of FPG,2 h PG and HbA1c at 6 months after the intervention in the observation group were lower than those in the control group,with statically significant differences(P＜0.05).The levels of FPG,2 h PG and HbA1c at 3 months and 6 months after the intervention in the observation group were lower than those in the control group,with statically significant differences(P＜0.05).After 6 months of intervention,the self-management behavior scores of observation group were higher than those in the control group,such as reasonable diet,proper exercise,blood glucose monitoring,foot care,taking medicine as prescribed by the doctor,and the differences were statistically significant(P＜0.05).Conclusion The implementation of"Internet plus" technology optimized medical care model can effectively improve the blood glucose compliance rate of elderly diabetic patients,reduce the HbA1c level of patients,reduce the incidence of hypoglycemia,and improve the self-management behavior of diabetic patients. 2021 Vol. 28 (13): 123-126 [Abstract] ( 39 ) HTML (37 KB)  PDF  (0 KB)  ( 5 ) 127 Clinical effect of Liraglutide combined with Metformin in the treatment of obese patients with type 2 diabetes mellitus DING Xiao-hui Objective To explore the clinical effect of Liraglutide combined with Metformin in the treatment of obese patients with type 2 diabetes mellitus.Methods A total of 80 obese patients with type 2 diabetes treated in Changda Hospital of Anshan City from January to June 2019 were selected as the research objects.According to random number table method,they were divided into observation group and control group,with 40 cases in each group.Observation group was treated with Liraglutide combined with Metformin,and control group was treated with Metformin,both groups were treated for 3 months.Hemoglobin A1c(HbA1c),fasting blood glucose(FBG),2 hours postprandial blood glucose(2 h PG),Homeostasis model assessment of insulin resistance(HOMA-IR),Homeostasis model assessment-β(HOMA-β),body mass index(BMI)before and after treatment and the incidence of adverse reactions during treatment in the two groups were compared.Results After treatment,FBG,2 h PG,HbA1c,BMI and HOMA-IR in the two groups were lower than those before treatment,and HOMA-β was higher than that before treatment,the differences were statistically significant(P＜0.05).After treatment,FBG,2 h PG,HbA1c,BMI,HOMA-IR in observation group were lower than those in control group,and HOMA-β was higher than that in control group,the differences were statistically significant(P＜0.05).There was 1 case of gastrointestinal reaction in the observation group and 1 case in the control group,and there was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion The Liraglutide combined with Metformin has obvious therapeutic effect on type 2 diabetes mellitus,which can effectively control blood glucose level,improve insulin function,promote insulin secretion,reduceinsulin resistance and BMI,with fewer adverse reactions,good safety.Therefore which has positive clinical significance.It is worth promoting. 2021 Vol. 28 (13): 127-129 [Abstract] ( 51 ) HTML (30 KB)  PDF  (0 KB)  ( 6 ) 130 Clinical effect of ultrasound-guided femoral nerve block combined with lateral femoral cutaneous nerve block for patella fracture surgery in elderly patients DENG Bi-sheng；GUI Fu-xin；JIANG Long-hua；QIN Kai；WANG Ya Objective To investigate the clinical effect of ultrasound-guided femoral nerve block combined with lateral femoral cutaneous nerve block for patella fracture surgery in elderly patients.Methods A total of 100 elderly patients with patella fractures who were admitted to Guangxin District People′s Hospital from October 2018 to March 2020 were selected as the research objects.According to the random number table method,they were divided into combined spinal-epidural anesthesia group(L group)and combined ultrasound-guided femoral nerve block Lateral femoral cutaneous nerve block group(N group),with 50 cases in each group.The hemodynamic indexes(diastolic blood pressure [DBP],systolic blood pressure [SBP],heart rate [HR])in the two groups at the time of anesthesia entry(T0),at the end of anesthesia(T1),at the beginning of surgery(T2)and at the end of surgery(T3)were compared.The total incidence of postoperative complications in the two groups was compared.Results The DBP and SBP at T1,T2 and T3 of the two groups were lower than those at T0,but the DBP and SBP at T1,T2,and T3 of the N group were higher than those of the L group,the difference in the interaction ratio between groups,time points,and between groups and time points was statistically significant(P＜0.05).At T1,T2 and T3,HR in both groups was lower than that in T0,and the difference at different time points was statistically significant(P＜0.05).There was no significant difference between groups,between groups and time point(P＞0.05).The total incidence of complications in group N was lower than that in group L,and the difference was statistically significant(P＜0.05).Conclusion The use of ultrasound-guided femoral nerve block combined with lateral femoral cutaneous nerve block in elderly patella fracture surgery can effectively control hemodynamics,keep vital signs relatively stable,enhance the analgesic effect and have high safety. 2021 Vol. 28 (13): 130-132-137 [Abstract] ( 44 ) HTML (34 KB)  PDF  (0 KB)  ( 7 ) 133 Comparison of effects of different doses of Desocine on the prevention of hyperalgesia after Remifentanil anesthesia DENG Wei-jie；HOU Jie；QIU Chi-yu；LIN Jie；JIANG Long Objective To investigate the effect of preoperative administration of Dezocine on hyperalgesia after Remifentanil anesthesia,and compare the preventive effect of different doses of Dezocine.Methods A total of 90 patients undergoing laparoscopic cholecystectomy under general anesthesia in Pingshan People′s Hospital from October 2018 to December 2019 were selected as the research subjects,according to the block randomization,they were divided into group A,group B and group C,with 30 cases in each group.The three groups were intravenously injected with the following drugs before surgery: in group A,Dezocine 0.05 mg/kg,in group B,Dezocine 0.1 mg/kg and in group C,normal saline(NS)0.9 mg/kg.The operation time,spontaneous breathing recovery time,consciousness recovery time,extubation time,visual analog scale(VAS)score,tramadol use and postoperative adverse reactions were compared among the three groups.Results There were no significant differences among the three groups in the time of operation,the time of spontaneous respiration recovery,the time of consciousness recovery and the time of extubation(P＞0.05);The VAS score of the patients in group A and B was lower than that in group C at 5 min after awakening,the difference was statistically significant(P＜0.05),while there was no statistically significance in the number of postoperative tramadol in group A and B(P＞0.05).No nausea,vomiting or dizziness occurred in the three groups after operation.There was no significant difference in the incidence of restlessness among the three groups(P＞0.05).Conclusion Since the use of low-dose Dezocine 0.05 mg/kg can achieve the desired effect,intravenous Dezocine 0.05 mg/kg before surgery is the recommended minimum effective dose to prevent hyperalgesia after remifentanil anesthesia. 2021 Vol. 28 (13): 133-137 [Abstract] ( 48 ) HTML (41 KB)  PDF  (0 KB)  ( 7 ) 138 Application of Dexmedetomidine combined with Remifentanil in nasopharyngeal airway placement in painless fiberbronchoscopy YIN Lin；YUAN Hai-bo；LU Fang；TU Wen-cai；LI Jian-hua；WANG Sheng-qiang Objective To investigate the application of Dexmedetomidine combined with Remifentanil in nasopharyngeal airway placement in painless fiberoptic bronchoscope.Methods A total of 60 patients undergoing fiberoptic bronchoscopy in Yichun People′s Hospital from January to July 2019 were selected as the research subjects.According to random drawing,they were divided into control group and observation group,with 30 cases in each group.Both groups were treated with Dexmedetomidine combined with Remifentanil anesthesia,the control group was treated with laryngeal mask anesthesia,and the observation group was treated with nasopharyngeal airway anesthesia.The hemodynamics,operative time,pain score,frequency of respiratory depression and incidence of adverse reactions in different stages were compared between the two groups.Results There was no statistically significant difference in hemodynamic indexes between the two groups of before anesthesia(T0),bronchoscopy mirror into the glottis(T1)(P＞0.05),the average arterial pressure,heart rate,respiratory rate and blood oxygen saturation of batients started bronchoscopy immediatdy(T2)bronchoscopy mirror arrived bulge immediately(T3),fiber mirror check completed immediately(T4)of the two groups were lower than T0,and the differences were statistically significant(P＜0.05).The observation group T2～T4 mean arterial pressure and oxygen saturation was higher than the control group,the difference was statistically significant(P＜0.05).The pain score and the total incidence of adverse reactions in the observation group were lower than those in the control group,and the number of respiratory depression was lower than that in the control group,and the differences were statistically significant(P＜0.05).There was no significant difference in operation time between the two groups(P＞0.05).Conclusion In painless fiberoptic bronchoscope,oxygen delivery through nasopharyngeal airway can reduce the fluctuation of hemodynamic indexes,relieve respiratory depression and pain,and reduce adverse reactions,which is worthy of promotion. 2021 Vol. 28 (13): 138-140-144 [Abstract] ( 42 ) HTML (33 KB)  PDF  (0 KB)  ( 7 ) 141 Effect of preemptive analgesia with Morphine combined low epidural anesthesia in lower limb orthopedic surgery for the elderly ZHOU Jun-qing Objective To explore the effect of preemptive analgesia with Morphine combined low epidural anesthesia in lower limb orthopedic surgery for the elderly.Methods A total of 60 elderly patients who underwent lower limb orthopedic surgery in Kangmei Hospital from March to September 2020 were selected as the research objects.According to the random number table method,they were divided into observation group and control group,with 30 cases in each group.Two groups of patients were routinely fasted and watered for 8 hours before operation,and no analgesics were used before operation.All patients were operated by the same anesthesiologist and given epidural anesthesia,and the control group was given 5 mL/(kg·h)saline intravenously 10 min before anesthesia.The observation group was given Morphine 1-1.5 mg(plus normal saline 5 mL)by intravenous injection.The alertness/sedation score(OAA/S),visual analogue scale(VAS),cognitive function(mini-mentalstateexa mination [MMSE]),analgesic duration and adverse reactions were compared between the two groups.Results OAA/S and VAS scores at 12,24 and 48 h after operation were lower than those at the end of operation,and the differences were statistically significant(P＜0.05).There was no significant difference in OAA/S scores between the two groups at each time point(P＞0.05).The VAS scores of the observation group at the end of operation and at 12 and 24 hours after operation were lower than those of the control group,and the differences were statistically significant(P＜0.05).The MMSE scores of the control group at 1 and 3 days after operation were lower than those before operation,and the differences were statistically significant(P＜0.05).There was no significant difference in MMSE scores at each time point in the observation group(P＞0.05).The MMSE scores of the observation group at 1 and 3 days after operation were higher than those of the control group,the differencse were statistically significant(P＜0.05).The analgesic duration of the observation group was longer than that of the control group,the difference was statistically significant(P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P＞0.05).Conclusion Preemptive analgesia with Morphine combined with low epidural anesthesia can achieve good sedative effects on elderly patients undergoing lower limb orthopedic surgery,and the analgesia lasts for a long time.Meanwhile,it can reduce the incidence of postoperative cognitive dysfunction. 2021 Vol. 28 (13): 141-144 [Abstract] ( 43 ) HTML (35 KB)  PDF  (0 KB)  ( 6 ) 145 Effect of fentanyl and Hegu acupoint injection on rapid recovery after cesarean section SUN Wen-hua；XU Rong-deng；HAN Xiao-yan；LIU Ding Objective To explore the effect of fentanyl Hegu acupoint injection on rapid recovery after cesarean section.Methods From November 2018 to March 2020,200 cases of maternal cesarean section in Gao′an Maternal and Child Health Care Hospital were selected and divided into control group and research group by random number table method,with 100 cases in each group.The control group was treated with fentanyl intravenous injection combined with intravenous analgesia,and the research group was treated with fentanyl acupoint injection combined with intravenous analgesia.The perioperative indexes,analgesia and comfort score,neonatal Apgar score and adverse reactions were compared between the two groups.Results The first exhaust time,eating time and ambulation time of the research group were shorter than those of the control group,and the intraoperative blood loss was less than that of the control group,the differences were statistically significant(P＜0.05).There was no significant difference in the amount of bleeding 24 h after operation between the two groups(P＞0.05);the visual anaglogue scale(VAS）and bruggrmann comfort scale(BCS）of the research group were lower than those of the control group,the differences were statistically significant(P＜0.05);there were no significant differences in the Apgar score of the two groups at 1 min and 5 min after delivery(P＞0.05).The incidence of adverse reactions in the research group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion Fentanyl combined with acupoint injection after cesarean section can effectively relieve maternal pain,improve comfort,with less adverse reactions and high safety.It can be used as the first choice for postoperative analgesia after cesarean section,which is worthy of promotion and application. 2021 Vol. 28 (13): 145-147-151 [Abstract] ( 43 ) HTML (33 KB)  PDF  (0 KB)  ( 7 ) 148 Application of Sevoflurane inhalation anesthesia in the operation of pediatric lower extremity fractures and its effect on hemodynamics YIN Zhi-wei Objective To explore the application of Sevoflurane inhalation anesthesia in the operation of pediatric lower extremity fractures and its effect on hemodynamics.Methods A total of 103 children who underwent lower limb fracture surgery in the Department of Anesthesiology,Zhuhai Center for Maternal and Child Health Care from June 2017 to July 2020 were selected as the research subjects.They were divided into control group(51 cases)and observation group(52 cases)according to the random number table method.The control group was given Ketamine basic anesthesia,while the observation group was given Sevoflurane inhalation anesthesia.The hemodynamic indexes,anesthetic quality and adverse reactions of the two groups were compared.Results There was no significant difference in blood oxygen saturation(SaO2),mean arterial pressure(MAP),heart rate(HR),systolic blood pressure(SBP)and diastolic blood pressure(DBP)between the two groups before anesthesia induction(P＞0.05).SaO2 and MAP in the observation group were higher than those in the control group,while HR,SBP and DBP were lower than those in the control group when eyelash reflex disappeared,immediately after skin incision and 5 min after skin incision,the differences were statistically significant(P＜0.05).SaO2 and MAP in the observation group were higher than those in the control group at the end of operation,and the differences were statistically significant(P＜0.05).There were no significant differences in HR,SBP and DBP between the two groups at the end of operation(P＞0.05).The onset time and awakening time of sensory block in the observation group were shorter than those in the control group,and the differences were statistically significant(P＜0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion Sevoflurane inhalation anesthesia can shorting the onset time and recovery time of anesthesia block in children undergoing lower extremity fracture surgery,reducing the incidence of anaesthesia related adverse reactions,and stabilizing hemodynamics. 2021 Vol. 28 (13): 148-151 [Abstract] ( 42 ) HTML (34 KB)  PDF  (0 KB)  ( 7 ) 152 Clinical value of high frequency ultrasound combined with magnetic sensitive imaging in the diagnosis of brain injury in preterm infants DING Xiao-jun；YANG Hong；ZHOU Cui-cui；XU Song；HUANG Zhi-ping；LIN Lin Objective To explore the clinical value of high-frequency ultrasound combined with magnetic sensitivity imaging(SWI)in the diagnosis of preterm infants with brain injury.Methods A total of 60 premature infants with high risk factors for brain injury who were delivered in Ganzhou People′s Hospital from August 2018 to February 2020 were selected as the research subjects,all preterm infants were examined by high-frequency ultrasound and SWI simultaneously.The positive detection rates,specificity,sensitivity and accuracy of high-frequency ultrasound alone,SWI alone and high-frequency ultrasound combined with SWI were compared,and the imaging findings of SWI in premature infants with brain injury were analyzed.Results The positive rate of preterm brain injury in the high-frequency ultrasound combined with SWI group was 97.50%,which was higher than that in the high-frequency ultrasound group alone(52.50%)and SWI group alone(77.50%),and the differences were statistically significant(P＜0.05).The specificity,sensitivity and accuracy of high-frequency ultrasound combined with SWI were higher than those of high-frequency ultrasound alone and SWI alone,and the differences were statistically significant(P＜0.05).SWI examination of premature infants with white matter injury showed spotty or patchy low signal.The hemorrhage foci of premature infants with intracranial hemorrhage showed low signal on SWI.The SWI of the children with cerebral edema showed different degree of high signal change.Conclusion High-frequency ultrasound is suitable for bedside dynamic monitoring of premature infants with unstable early stage.High-frequency ultrasound combined with SWI has a high diagnostic positive rate for brain injury in preterm infants,which is worthy of clinical promotion. 2021 Vol. 28 (13): 152-155 [Abstract] ( 42 ) HTML (33 KB)  PDF  (0 KB)  ( 7 ) 156 Value analysis of echocardiography in the early diagnosis of Kawasaki disease coronary artery disease HUANG Li-rong Objective To investigate the value of echocardiography in the early diagnosis of coronary artery disease in Kawasaki disease.Methods A total of 40 patients with suspected Kawasaki disease with coronary artery disease admitted to Heyuan Maternal and Child Health Hospital from December 2018 to March 2020 were selected as the research subjects,echocardiography and electrocardiogram(ECG)were performed in all patients.The detection rate,sensitivity,specificity and imaging characteristics of the two detection methods were compared.Results The diagnostic coincidence rate,sensitivity and specificity of echocardiography were 85.00%,88.24% and 66.67%.The diagnostic coincidence rate,sensitivity and specificity of ECG were 52.50%,52.38% and 52.63%,and the differences were statistically significant(P＜0.05).For patients with sinus tachycardia,the time to return to normal was(4.17±0.21)months.In patients diagnosed with coronary aneurysms,the time to return to normal was(20.12±0.17)months.During the follow-up,no lumen ＜1.5 mm cases occurred,and no recurrence cases occurred.Conclusion Echocardiography is very important for early diagnosis of Kawasaki disease patients with coronary artery disease and can improve the detection rate. 2021 Vol. 28 (13): 156-158 [Abstract] ( 42 ) HTML (27 KB)  PDF  (0 KB)  ( 5 ) 159 Value of echocardiography combined with electrocardiogram in the diagnosis of hypertensive heart disease LI Zhi-yong LI Xing HE Zhen LEI Li-qin YE Bao-yong Objective To investigate the value of echocardiography combined with electrocardiogram in the diagnosis of hypertensive heart disease.Methods A total of 50 patients with hypertensive heart disease who were treated in the Second People′s Hospital of Jingdezhen from October 2019 to July 2020 were randomly selected as the research objects.According to the random number table method,they were divided into two groups,with 25 cases in each group.The control group underwent the single echocardiography,and the test group underwent echocardiography combined with electrocardiogram examination.The cardiac examinations and diagnostic results were compared between two groups,at the same time,the angiocardiography diagnosis was used to confirm the diagnosis.Results There were no statistically significant differences in heart-related examination indicators between the two groups(P＞0.05).The detection rates of left ventricular enlargement,left ventricular hypertrophy,rhythm changes,and left ventricular hypertrophy strain in the test group were higher than those in the control group,and the differences were statistically significant(P＜0.05).All patients were hypertensive heart disease by the examination of angiocardiography,and the result of angiocardiography was taken as the "gold standard",the area under the curve(0.864)and sensitivity of the combined detection of myocardial function were higher than those of the single detection of echocardiography,and the diagnostic efficiency was higher.Conclusion Echocardiography combined with electrocardiogram can detect the impaired cardiac function in patients with hypertensive heart disease,which is conductive to early diagnosis and treatment. 2021 Vol. 28 (13): 159-161-165 [Abstract] ( 42 ) HTML (31 KB)  PDF  (0 KB)  ( 5 ) 162 Study on the application value of carotid artery ultrasound in screening high-risk population of stroke TANG Qing-wu；WANG Qing-fei；ZHU Xiang-bao Objective To explore the clinical value of carotid artery ultrasound in screening high-risk population of stroke.Methods From August 2018 to June 2020,360 residents were selected for investigation in Leping City,Jiangxi Province,and the residents surveyed were all over 40 years old.According to 8+2 stroke risk factors,the respondents were divided into healthy group,low-risk group,intermediate-risk group and high-risk group,with 90 cases in each group.The basic living habits and plaque detection rate of residents were investigated.The color Doppler ultrasound detection instrument was used for carotid artery ultrasound detection,and the clinical application value of carotid artery ultrasound detection was analyzed.Results There were 102 cases of neck vascular plaque formation in 360 subjects,with a total detection rate of 28.33%;a total of 101 cases of media thickening were detected,with a total detection rate of 28.06%.The detection rates of neck vascular plaque and media thickening in the high-risk group were higher than those in the intermediate-risk group,low-risk group,and healthy group,and the differences were statistically significant(P＜0.05).The detection rates of neck vascular plaque and media thickening in the intermediate-risk group were higher than those in the low-risk group and healthy group,and the differences were statistically significant(P＜0.05).The detection rates of neck vascular plaque and media thickening in the low-risk group were higher than those in the healthy group,and the differences were statistically significant(P＜0.05).The total detection rates of single and multiple plaques in the high-risk group were higher than those in the intermediate-risk group,low-risk group and healthy group,and the differences were statistically significant(P＜0.05).The total detection rates of single and multiple plaques in the intermediate-risk group were higher than those in the low-risk group and healthy group,and the differences were statistically significant(P＜0.05).The total detection rates of single and multiple plaques in the low-risk group were higher than those in the healthy group,and the differences were statistically significant(P＜0.05).Conclusion The application of carotid artery ultrasound detection in screening high-risk population of stroke can effectively distinguish high-,medium-,and low-risk stroke populations,and clarify the thickening of the media and the nature of plaque,which provides rich imaging data for clinical interventions. 2021 Vol. 28 (13): 162-165 [Abstract] ( 43 ) HTML (34 KB)  PDF  (0 KB)  ( 7 ) 166 Effect comparison between Nimotuzumab combined with intensity-modulated radiotherapy and radiotherapy alone in the treatment of locally advanced nasopharyngeal carcinoma ZHANG Xiao-xiao Objective To compare the effect between Nimotuzumab combined with intensity-modulated radiotherapy(IMRT)and radiotherapy alone in the treatment of locally advanced nasopharyngeal carcinoma.Methods A total of 100 patients with locally advanced nasopharyngeal carcinoma who were admitted to Anshan Cancer Hospital from April 2015 to April 2017 were selected as the research subjects,and they were divided into the control group(50 cases)and the intervention group(50 cases)according to the random lottery method.Patients in the control group received IMRT alone,and patients in the intervention group were treated with Nimotuzumab for targeted therapy on the basis of IMRT.The therapeutic effect,survival period(overall survival [OS],progression-free survival [PFS]),quality of life,and incidence of adverse reactions were compared between the two groups.Results The total effective rate and disease control rate of the intervention group were higher than those of the control group,and the differences were statistically significant(P＜0.05).The OS and PFS of the intervention group were longer than those of the control group,and the quality of life score was higher than that of the control group,the differences were statistically significant(P＜0.05).The total incidence of adverse reactions in the intervention group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion The effect of Nimotuzumab combined with IMRT is significantly better than that of radiotherapy alone in the treatment of locally advanced nasopharyngeal carcinoma.It can improve the local control rate,improve the quality of life of patients,and prolong their survival.It is worthy of popularization and application. 2021 Vol. 28 (13): 166-168-172 [Abstract] ( 72 ) HTML (31 KB)  PDF  (0 KB)  ( 7 ) 169 Clinical effect and safety analysis of CT in the diagnosis of intestinal obstruction TONG Xin Objective To explore the clinical effect and safety of CT in the diagnosis of intestinal obstruction.Methods A total of 100 patients with suspected intestinal obstruction admitted to Fushun Central Hospital from July 2018 to June 2020 were retrospectively selected as the research objects.The X-ray and CT data of all patients were analyzed based on the surgical results as the gold standard.The image clarity,the detection of each type of intestinal obstruction,the detection of the etiology of intestinal obstruction and the comfort of patients during the examination were compared between the two methods.Results The image clarity rate of CT examination was 95.00%,which was higher than that of X-ray examination(83.00%),the difference was statistically significant(P＜0.05).The total detection rate of intestinal obstruction was 84.00% by CT examination and 59.00% by X-ray examination.The total detection rate of intestinal obstruction was 85.00% by CT examination and 61.00% by X-ray examination.There was no significant difference between the two methods in the specificity of various types of intestinal obstruction and the cause of intestinal obstruction(P＞0.05),but the sensitivity and accuracy of CT examination were higher than that of X-ray examination,the differences were statistically significant(P＜0.05).The total comfort rate of CT examination patients was 97.00%,which was higher than that of X-ray examination(89.00%),and the difference was statistically significant(P＜0.05).Conclusion CT examination is effective in diagnosing intestinal obstruction,can accurately detect different types of intestinal obstruction,etiology,and examination of high safety and comfort. 2021 Vol. 28 (13): 169-172 [Abstract] ( 42 ) HTML (32 KB)  PDF  (0 KB)  ( 7 ) 173 Evaluation of the diagnostic effect of conventional electroencephalography and sphenoid electroencephalography combined in different types of epilepsy WANG Huan Objective To explore the diagnostic effect of electroencephalography(EEG)combined with conventional electroencephalography and sphenoid electroencephalography(SPE)in different types of epilepsy.Methods A total of 200 patients with epilepsy admitted to Beijing Yangfangdian Hospital from January 2018 to August 2020 were randomly selected as the research subjects,including 50 patients with general epilepsy and 150 patients with partial epilepsy,of which 50 patients with medial temporal lobe epilepsy and 100 patients with non-medial temporal lobe epilepsy were included in partial epilepsy.All patients underwent conventional EEG and SPE.The detection rate of epileptic discharge in patients with different types of epilepsy was compared by using two EEG methods alone and combining two EEG methods.Results In the diagnosis of patients with general epilepsy,the detection rate of epileptic discharge by combined examination was higher than that by sphenoid electrode examination,and the difference was statistically significant(P＜0.05).In the diagnosis of patients with partial epilepsy,the detection rate of epileptic discharges by the combined examinations was higher than that of the sphenoid electrode examination,and the difference was statistically significant(P＜0.05).In the diagnosis of patients with medial temporal lobe epilepsy,the epileptic discharge detection rate of sphenoid electrode examination and combined examination was higher than that of conventional electrode examination,and the difference was statistically significant(P＜0.05),and there was no significant difference in the detection rate of epilepsy between the combined test and sphenoid electrode test(P＞0.05).In the diagnosis of patients with non-medial temporal epilepsy,the detection rate of epileptic discharge by combined examination was higher than that by sphenoid electrode examination,and the difference was statistically significant(P＜0.05).Conclusion Sphenoid electrode examination is of high diagnostic value in patients with medial temporal lobe epilepsy,but for patients with non-medial temporal lobe epilepsy and generalized epilepsy,combined sphenoid electrode and conventional electrode examinations is required with a favorable effect. 2021 Vol. 28 (13): 173-175 [Abstract] ( 40 ) HTML (29 KB)  PDF  (0 KB)  ( 6 ) 176 Analysis of intervention effect of clinical pharmacists for the irrational parenteral nutrition prescription XIAO Dong-mei；YAO Guo-qiang；WU Si-ping Objective To investigate the intervention effect of clinical pharmacists on unreasonable parenteral nutrition orders.Methods The clinical data of 47 children with parenteral nutrition from June 2019 to July 2019 treated in Pingxiang People′s Hospital were retrospectively analyzed,according to whether there was clinical pharmacist intervention for the review of parenteral nutrition prescription,the research subjects were divided into the control group(n=23)and the observation group(n=24).The parenteral nutrition prescription review in the control group did not have clinical pharmacist intervention,and the parenteral nutrition prescription review in the observation group was intervened by clinical pharmacists.The rational use rate of total nutrient admixtare(TNA)prescription,hospitalization time and hospitalization expenses of each department were compared between the two groups.Results The rationality of TNA prescription of patients in the observation group was higher than the control group,and the difference was statistically significant(P＜0.05);the hospitalization time of the observation group was shorter than the control group,and the expense was lower than the control group,the differences were statistically significant(P＜0.05).Conclusion Clinical pharmacists review the prescriptions of parenteral nutrition solutions,rationally and effectively intervene in unreasonable prescriptions,improve the rationality of prescriptions,reduce the hospital stay and hospitalization expenses of patients,and ensure the safety of patients′medication. 2021 Vol. 28 (13): 176-178 [Abstract] ( 42 ) HTML (28 KB)  PDF  (0 KB)  ( 6 ) 179 Analysis of medication for metformin in the treatment of polycystic ovary syndrome HU Xiao Objective To investigate the application of metformin in polycystic ovary syndrome(PCOS),so as to provide a reference for clinical rational drug use.Methods The outpatient prescriptions of patients with diagnosed PCOS in Fujian Provincial Hospital from January 2018 to December 2019 were selected to analyze the use of metformin in PCOS prescriptions.Results A total of 282 PCOS prescriptions were selected,including 97 prescriptions with metformin monotherapy and 111 prescriptions with metformin combined with other drugs(103 for double combination and 8 for triple combination).The main drugs used in combination included dydrogesterone tablets,ethinylestradiol and cyproterone acetate tablets,pioglitazone hydrochloride tablets and spironolactone tablets.A total of 25 irrational prescriptions were found,mainly with inappropriate usage and dosage.Conclusion Metformin is mainly used in combination with other PCOS drugs in the treatment of PCOS.The combined use of drugs is basically rational,but there are still some unreasonable situations in dosage,frequency of administration and usage. 2021 Vol. 28 (13): 179-182 [Abstract] ( 50 ) HTML (33 KB)  PDF  (0 KB)  ( 5 ) 183 Comparative Study on the Diagnosis and Treatment of Rheumatoid Arthritis JI Sen-guo；ZHANG Xu-ming；WU Di；LIU Ju Objective To explore the application effect of combined traditional Chinese medicine treatment of rheumatoid arthritis(RA).Methods A total of 120 RA patients admitted to the Department of Rheumatology and Immunology of Jiujiang First People′s Hospital from August 2017 to December 2019 were selected as the research subjects.According to random number table method,they were divided into western medicine group and combined group,with 60 cases in each group.The western medicine group was treated with western medicine treatment plan,while the combination group was treated with Chinese medicine treatment plan.Clinical efficacy,improvement of symptoms and signs before and after treatment,laboratory indicators and the incidence of ADR were compared between the two groups.Results The total effective rate of combined group was higher than that of western medicine group,and the difference was statistically significant(P＜0.05).After treatment,the joint pain score,joint tenderness index and joint swelling index of the combined group were lower than those of the western medicine group,and the morning stiffness time was shorter than that of the western medicine group,the differences were statistically significant(P＜0.05).Joint function of the combined group was better than that of the western medicine group,and the difference was statistically significant(P＜0.05).The cell sedimentation rate and C-reactive protein level in the combined group were lower than those in the western medicine group,the differences were statistically significant(P＜0.05).No obvious adverse reactions occurred in two groups during treatment.Conclusion The combined treatment of traditional Chinese medicine has a definite effect on RA,and the patients have a good recovery of joint function,which can promote the recovery of prognosis,and is worthy of clinical promotion. 2021 Vol. 28 (13): 183-186 [Abstract] ( 38 ) HTML (35 KB)  PDF  (0 KB)  ( 5 ) 187 Application effect of Jianpi Yiqi Huashi Recipe in the treatment of radiation enteritis caused by radiotherapy of rectal cancer FU Zu-de Objective To observe the application effect of Jianpi Yiqi Huashi Recipe in the treatment of radiation enteritis caused by radiotherapy of rectal cancer.Methods A total of 68 patients with radiation enteritis caused by radiotherapy for rectal cancer who were admitted to the University of Chinese Academy of Sciences,Shenzhen Hospital from April 2019 to April 2020 were selected as the research objects.They were divided into the reference group and the research group by random number table method,with 34 patients in each group.Patients in the reference group were treated with Glutamine,Montmorillonite Powder,and Metronidazole Injection for symptomatic treatment,while in the research group,Jianpi Yiqi Huashi Recipe was added on the basis of the reference group.After two weeks of treatment,the curative effect,symptom scores and symptom total score of abdominal pain,diarrhea,hematochezia and acute symptoms were compared between the two groups.Results The total effective rate of the research group(91.18%)was higher than that of the control group(76.47%),and the difference was statistically significant(P＜0.05).Before treatment,there were no statistically significant differences in symptom scores and total symptom scores between the two groups(P＞0.05).After treatment,symptom scores of abdominal pain,diarrhea,hematochezia and acute symptoms and symptom total score of the two groups were lower than those before the treatment,the differences were statistically significant(P＜0.05),the symptom scores of abdominal pain,diarrhea,hematochezia and acute symptoms and symptom total score of the research group were lower than those of the control group,the differences were statistically significant(P＜0.05).Conclusion In the treatment of patients with radiation enteritis caused by radiotherapy for rectal cancer,the use of Jianpi Yiqi Huashi Recipe assisted with conventional western medicine treatment can promote the improvement of patients′clinical symptoms and increase the clinical efficacy,which has clinical promotion value. 2021 Vol. 28 (13): 187-189-197 [Abstract] ( 40 ) HTML (31 KB)  PDF  (0 KB)  ( 4 ) 190 Experience of treating high anal fistula by Professor MAO Xi-Yun LI Ming-Yue；MAO Xi-Yun For the treatment of high anal fistula,Professor Mao Xi-yun believes that according to the patient's condition,the green anorectal treatment concept "minimally invasive,painless,safe and effective,humanistic care" should be guided,and comprehensive use of different surgical methods,accurate positioning of fistula and internal orifice,correct treatment of the internal orifice,complete removal of fistula,smooth drainage,and pay attention to protect the anal sphincter complex,to maintain the shape and function of the anus.Attention is paid to postoperative dressing change.Professor Mao Xi-yun believes that the quality of postoperative dressing change determines the success or failure of anal fistula operation.Anal fistula postoperative dressing,should ensure smooth drainage,should also pay attention to the gentle technique,avoid "fierce rub,fierce stab,fierce plug".Make good use of traditional Chinese medicine,Professor Mao Xi-yun believes that traditional Chinese medicine has a significant effect on relieving pain after anal fistula and promoting wound healing after anal fistula.Rational use of characteristic therapies of traditional Chinese medicine can improve patients' postoperative experience and shorten the time of wound healing. 2021 Vol. 28 (13): 190-193 [Abstract] ( 74 ) HTML (37 KB)  PDF  (0 KB)  ( 5 ) 194 Clinical effect of Gushen Antai Pill combined with Dydrogesterone in the treatment of threatened abortion due to kidney yin deficiency XIONG Fei；ZHOU Chao Objective To investigate the clinical effect of Gushen Antai Pill combined with Dydrogesterone in the treatment of threatened abortion due to kidney yin deficiency.Methods A total of 100 patients with early threatened abortion due to kidney yin deficiency who visited First People′s Hospital of Fuzhou City from October 2018 to October 2019 were selected as the research objects.They were divided into the control group and the observation group according to the order of admission,with 50 cases in each group.Both groups received oral administration of vitamin E and folic acid tablets after admission.Patients in the control group were treated with Gushen Antai Pills combined with Intramuscular Progesterone.In the observation group,participants were treated with Gushen Antai Pills combined with oral administration of Dydrogesterone Tablets.The levels of serum progesterone(P),estradiol(E2)and β-human chorionic gonadotropin(β-HCG)in the two groups were compared.After the delivery of the patients,the efficacy of fetal preservation(the success rate of fetal preservation and the rate of live delivery)and the total incidence of adverse reactions were compared between the two groups.Results Before treatment,there were no statistically significant differences in the serum levels of P,E2 and β-HCG levels between the two groups(P＞0.05).After treatment,the levels of serum P,E2 and β-HCG in the two groups were higher than those before treatment,and the serum levels of P,E2 and β-HCG in the observation group were higher than those in the control group,the differences were statistically significant(P＜0.05).The success rate of fetal preservation and live birth rate of the observation group were higher than those of the control group,and the differences were statistically significant(P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P＞0.05).Conclusion For patients with early threatened abortion due to deficiency of kidney yin,Gushen Antai Pill combined with Dydrogesterone Tablets has a more remarkable fetal-preserving effect,which can effectively increase the levels of sex hormones and improve the final pregnancy outcome. 2021 Vol. 28 (13): 194-197 [Abstract] ( 46 ) HTML (34 KB)  PDF  (0 KB)  ( 7 ) 198 Effect of Xiaoqinglong Decoction combined with noninvasive ventilator on blood gas index and lung function in elderly patients with acute exacerbation of chronic obstructive pulmonary disease DU Ting-ting Objective Effect of Xiaoqinglong Decoction combined with noninvasive ventilator on blood gas index and pulmonary function in elderly patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods A total of 90 elderly patients with AECOPD who admitted to the Fourth People′s Hospital of Dalian from January 2019 to February 2020 were selected as the research object,they were divided into the traditional Chinese medicine(TCM)group and the western medicine group according to random numbers table method,with 45 cases in each group.The western medical group was treated with routine therapy combined with noninvasive ventilator,the TCM group was treated with Xiaoqinglong Decoction combined with noninvasive ventilator.The curative effect,blood gas indexes(partial pressure of carbon dioxide [PaCO2],oxygen partial pressure [PaO2])and lung function(forced vital capacity [FVC],forced expiratory volume in the first second [FVC1],and the percentage of forced expiratory volume in the first second to forced vital capacity [FEV1/FVC])were compared between the two groups.Results The total effective rate in TCM group was higher than that in western medicine group,and the difference was statistically significant(P＜0.05).Before treatment,there were no statistically significant differences in blood gas index and lung function index between the two groups(P＞0.05).After treatment,FVC,FEV1,FEV1/FVC and PaO2 in TCM group were higher than those in western medicine group,and PaCO2 was lower than that in western medicine group,and the differences were statistically significant(P＜0.05).Conclusion Xiaoqinglong Decoction combined with noninvasive ventilator is effective in the elderly patients with AECOPD,which can significantly improve the blood gas analysis index and promote the recovery of lung function. 2021 Vol. 28 (13): 198-200-204 [Abstract] ( 43 ) HTML (33 KB)  PDF  (0 KB)  ( 5 ) 201 Clinical effect of Catalysis Decoction combined with Oxytocin in preventing postpartum hemorrhage WU Qian；XU Jie；HAN Yue Objective To observe the effect of Catalysis Decoction combined with Oxytocin in preventing postpartum hemorrhage.Methods A total of 60 cases who delivered naturally without pregnancy and childbirth complications in the Department of Obstetrics,Changde Hospital Affiliated to Hu′nan University of Chinese Medicine from March 2019 to May 2020 were selected as the research objects.The patients were divided into observation group and control group by random number table method,with 30 cases in each group.In the observation group,on the basis of western medicine treatment,the puerpera in the uterine mouth opened for 3 cm,the uterine mouth opened for 2 h and the postpartum orally prepared 1 dose of Catalysis Decoction.The control group was treated with Oxytocin only.The preventive effect of postpartum hemorrhage and the amount of postpartum hemorrhage were compared between the two groups.Results The amount of postpartum bleeding at 2 and 24 h in the observation group were less than those in the control group,and the differences were statistically significant(P＜0.05).The TCM symptom score 24 h after treatment in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).The incidence of postpartum hemorrhage in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).There was no significant difference in the incidence of nausea and vomiting between the two groups(P＞0.05).Conclusion Catalysis Decoction combined with Oxytocin can effectively prevent postpartum hemorrhage,and has less adverse drug reactions. 2021 Vol. 28 (13): 201-204 [Abstract] ( 47 ) HTML (36 KB)  PDF  (0 KB)  ( 9 ) 205 Analysis on compliance of the proton-pump inhibitors for injection in clinical application CHEN Mi-lin；YANG Jing-ran；ZHANG Hui-feng；LIU Yu；WANG Jia-zuo；WANG Ming-xing；DOU Ti-e；GUO Wei-yi Objective To investigate the compliance and rationality of clinical infusion of proton-pump inhibitors in a top three hospital in Yunnan Province.Methods Field research and investigation were used to analyze the irregularities in clinical infusion of proton-pump inhibitors in a top three hospital in Yunnan Province from October 21 to November 20,2019,including infusion flushing tube,infusion time,placement time,etc.Results There were some irregularities in clinical infusion,mainly focusing on drugs with special requirements such as infusion flushing tube,protecting from light and immediate use,which occupied 39.84%.Among them,559 cases(26.17%)failed to meet the requirements under flushing tube requirements,and the PPIs accounted for 70.43%.Among the infusion products,which were placed for a long time,parenteral nutrient solution and reduced glutathione accounted for 17.69% over 3 hours,and PPIs accounted for 35.54% placed for 1 hour.Conclusion According to the characteristics of PPIs,for drugs with infusion flushing tube,infusion time limit and compatibility requirements,the order of use should be adjusted to reduce the waiting time for clinical infusion,so as to avoid potential risks of clinical infusion in detail. 2021 Vol. 28 (13): 205-207 [Abstract] ( 39 ) HTML (31 KB)  PDF  (0 KB)  ( 6 ) 208 Investigation and study on knowledge,attitude and practice of traditional Chinese medicine nursing in Xintai Hospital of Traditional Chinese Medicine YANG Xiao-xue；WANG Yu-jie；WU Ya-jing Objective To investigate and analyze the knowledge,attitude and practice of traditional Chinese medicine nursing among nurses in Xintai City.Methods In December 2017,134 caregivers from Xintai Hospital of Traditional Chinese Medicine were randomly selected for analysis of the current state of knowledge and performance survey of traditional Chinese medicine nursing using a questionnaire survey.Results Among 134 nurses,5(3.7%)were male nurses and 129(96.3%)were female nurses;60(44.8%)were ≤30 years,70(52.2%)were ＞30-40 years,and 4(3.0%)were＞40-50 years.Years of working: 46(34.3%)were 0-5 years,69(51.5%)were ＞5-10 years,and 19(14.2%)were ＞10 years.Education: 26(19.4%)were specialist,108(80.6%)were undergraduate and above.Job title: 33(24.06%),primary carer 62(46.3%),head carer and above 39(29.1%).The nurses scored(15.22±2.40)in traditional chinese medicine nursing knowledge,(32.30±4.16)points in attitude and belief,and(32.86±17.74)points in behavior.Nurses aged ＞30-40 years had higher traditional Chinese medicine nursing knowledge scores than nurses of other ages,nurses with working years ＞10 years had higher scores than nurses of other ages,nurses with undergraduate and above qualifications had higher scores than specialist nurses,nurses in charge and above job titles had higher scores than nurses of other job titles,and the differences were statistically significant(P＜0.05).Female nurses had higher scores for attitude and belief of traditional Chinese medicine nursing than male nurses,nurses aged ＞30-40 years had higher scores than other nurses of all ages,nurses aged ＞10 years had higher scores than other nurses of all years,nurses of undergraduate and above had higher scores than specialist nurses,supervisor nurse and above had higher scores than nurses of other job titles,with statistically significant differences(P＜0.05).There were no significant differences in scores of traditional Chinese medicine nursing behaviors between nurses of different genders,ages,job years,academic qualifications,and job titles(P＞0.05).Conclusion Nurses have a high degree of Knowledge,attitude and practice in traditional Chinese medicine nursing,and there is great room for improvement in traditional Chinese medicine nursing practice.The hospital should increase the training of traditional chinese medicine nursing talents to meet the needs of social development. 2021 Vol. 28 (13): 208-211 [Abstract] ( 45 ) HTML (34 KB)  PDF  (0 KB)  ( 5 ) 212 Analysis of the correct use of insulin in diabetic patients in Fuzhou Maternal and Child Health Hospital LI Hai-yan；HUANG Sheng-cai；CHEN Li-ping；SHAN Guo-lin；ZHOU Xue-qin Objective To analyze the correct use of insulin in diabetic patients in Fuzhou Maternal and Child Health Hospital.Methods From April 2018 to April 2019,355 patients with type 2 diabetes in Fuzhou Maternal and Child Health Hospital(the Second People′s Hospital)were selected,and all of them received insulin treatment for more than 6 months.A questionnaire was designed to investigate the use of insulin and insulin injections.Results A total of 355 questionnaires were distributed and all the questionnaires were collected.The effective response rate was 100%.The results of the questionnaire showed that the patients had a better grasp in insulin pen and insulin match,correctly installing the insulin pen and insulin needle,injection at the prescribed time and number of times in accordance with the doctor′s advice,and injecting insulin to avoid hyperplasia,scars,and infection sites,but poor in storing the insulin pen and insulin correctly,washing hands before injecting insulin,checking the dosage and type of insulin before injecting insulin,disinfecting the skin with alcohol before injecting insulin,injecting insulin at a 90° angle,changing the insulin needle each time,and the distance between the injection site and the last injection more than 3 cm.Conclusion Type 2 diabetes patients in Fuzhou Maternal and Child Health Hospital still have deficiencies in storing the insulin pen and insulin correctly,washing hands before injecting insulin,checking the dosage and type of insulin before injecting insulin,disinfecting the skin with alcohol before injecting insulin,injecting insulin at a 90° angle,changing the insulin needle each time,and the distance between the injection site and the last injection more than 3 cm,and they need continuous improvement to continuously improve their correct use of insulin. 2021 Vol. 28 (13): 212-214 [Abstract] ( 40 ) HTML (29 KB)  PDF  (0 KB)  ( 8 ) 215 Impact of individualized health education on the intervention effect of knowledge,attitude and practice for family close contacts of tuberculosis patients LI Min；GAO Xiu-ping Objective To study the impact of individualized health education on the intervention effect of knowledge,attitude and practice for family close contacts of tuberculosis patients.Methods A total of 200 family close contacts of tuberculosis patients received by Xinzhou Center for Disease Control and Prevention of Wuhan City from August to December 2019 were selected as the research objects.They were divided into the intervention group and the control group according to the random lottery method,with 100 cases in each group.Individualized health education measures were implemented for the intervention group,and the control group was provided with general disease-related knowledge education.A questionnaire survey of knowledge,attitude and practice was conducted after 3 months.The scores of core information awareness,positive attitudes and prevention practice of the two groups were compared.Results After intervention,the scores of core information awareness,positive attitudes and prevention practice of the intervention group were higher than those of the control group,the differences were statistically significant(P＜0.05).Conclusion Individualized health education has a very significant effect on the knowledge,attitude and practice intervention of family close contacts of tuberculosis patients.It can increase the awareness rate of tuberculosis-related knowledge of close contacts,change their attitudes and health practice about tuberculosis prevention and control,and become extremely positive in tuberculosis prevention and control,which is beneficial to the prevention and control of tuberculosis and has promotion value. 2021 Vol. 28 (13): 215-218 [Abstract] ( 44 ) HTML (35 KB)  PDF  (0 KB)  ( 7 ) 219 Epidemiology and clinical characteristics of premature infants JIANG Jun-yu Objective To explore the epidemiological and clinical characteristics of preterm infants.Methods The clinical data of 219 premature infants delivered in the Department of Neonatal Internal Medicine,Dongguan Kanghua Hospital from January 2018 to January 2019 were analyzed retrospectively(the premature infant mortality rate was 0%).The perinatal,gestational age distribution,body weight distribution and complication distribution of the above preterm infants were counted.Results The gestational age of premature infants hospitalized in Dongguan Kanghua Hospital was mainly 33-＜37 weeks(67.5%).The main birth weight was 1500-2499 g(75.7%).Apgar score ranged from 2 to 10 points within 1 minute,with an average score of(7.25±0.50)points.The incidence of asphyxia was 17.8%.The main causes of premature delivery are premature rupture of membranes,pregnancy induced hypertension syndrome,multiple pregnancy,placental abruption,assisted reproductive technology,intrahepatic cholestasis of pregnancy and gestational diabetes mellitus.The incidence of premature rupture of membranes,pregnancy induced hypertension syndrome,multiple pregnancies and gestational diabetes mellitus in premature infants aged 27-＜30 weeks,30-＜33 weeks and 33-＜37 weeks decreased in turn(P＜0.05).The common complications of premature infants are respiratory diseases,infections,circulatory diseases,hyperbilirubinemia,electrolyte disorders and digestive diseases.The incidence of respiratory diseases,infection,hyperbilirubinemia,electrolyte disturbance and digestive system diseases in premature infants aged 27-＜30 weeks,30-＜33 weeks and 33-＜37 weeks decreased in turn(P＜0.05).Conclusion The common causes of premature babies are relatively clear.Complications in children are more common in respiratory diseases.There are some differences in the causes and complications of preterm delivery at different gestational ages. 2021 Vol. 28 (13): 219-221 [Abstract] ( 44 ) HTML (1 KB)  PDF  (0 KB)  ( 7 ) 222 Analysis and suggestions on 3 cases of neurotoxicity induced by Oxaliplatin for injection PEI Ping；SUN Zhan-jun Oxaliplatin is a new platinum derivative,which belongs to the third generation of platinum based broadspectrum antineoplastic drugs.Oxaliplatin has shown a determined curative effectin gastrointestinal cancer as adjuvant chemotherapy or first-line chemotherapy after metastasis.However,due to the toxicity of Oxaliplatin and the long use cycle,adverse reactions occur frequently in patients during the treatment process,and adverse consequences will be caused if no active measures are taken.The incidence of neurotoxicity was higher among all Oxaliplatin adverse reactions.The objective of this paper is to learn the influencing factors of neurotoxicity induced by Oxaliplatin through 3 clinical cases,and to provide suggestions to reduce the incidence rate of neurotoxicity.This case analysis explains that it is particularly important to carry out pharmaceutical care in antineoplastic drug therapies to prevent possible adverse drug reactions. 2021 Vol. 28 (13): 222-224 [Abstract] ( 45 ) HTML (29 KB)  PDF  (0 KB)  ( 6 ) 225 A case analysis of one patient with in-stent thrombosis after percutaneous coronary intervention SU Hong；HAN Rui-lan In this paper,the treatment of a patient with in-stent thrombosis after percutaneous coronary intervention(PCI)was analyzed in order to provide reference for in-stent thrombosis caused by drugs.The patient developed instent restenosis 1 year after coronary stent implantation.The pharmacist analyzed the patient′s drugs and found that it was related to Clopidogrel resistance.It is suggested that the patients should be examined for gene polymorphism.The results showed that the patient was slow metabolic type.It is suggested that Clopidogrel should be replaced with tigrel,and the platelet aggregation rate can reach the standard after replacement of tigrel,indicating that antiplatelet therapy was effective.Clinical pharmacists provide reference for clinical through the analysis of drugs used by patient. 2021 Vol. 28 (13): 225-227-241 [Abstract] ( 43 ) HTML (30 KB)  PDF  (0 KB)  ( 7 ) 228 Application effect of comprehensive nursing in hospitalized children with high risk of malnutrition CAO Juan-juan；DAI Xin-fang；YANG Liang Objective To explore the application effect of comprehensive nursing in hospitalized children with high risk of malnutrition,and to provide references for clinical interventions.Methods A total of 120 hospitalized children with a high risk of malnutrition at the Jiujiang Maternity and Child Health Hospital in Jiangxi Province from October 2018 to August 2019 were selected as the research objects,and were divided into the control group(60 cases)and the study group(60 cases)according to random number table method.The control group received routine nursing,and the study group added comprehensive nursing.After the intervention,the clinical efficacy,hospitalization of children,parental health knowledge mastery and nursing satisfaction were compared between the two groups after intervention,and the results of statistical nutrition evaluation were followed up for 3,6 and 12 months.Results The total clinical effective rate of the study group at discharge was higher than that of the control group,the length of hospital stay was shorter than that of the control group,and the cost of hospitalization was lower than that of the control group,the differences were statistically significant(P＜0.05).The parental health knowledge mastery and total satisfaction of the study group were higher than those of the control group,the risk of malnutrition in the study group was lower than that of the control group after 3 months of intervention,the differences were statistically significant(P＜0.05).Conclusion The implementation of comprehensive nursing in hospitalized children with high risk of malnutrition can improve the clinical effect,shorten the length of hospitalization,reduce hospitalization costs,and at the same time improve the parents of children with nutritional knowledge and nursing satisfaction,and reduce the risk of malnutrition. 2021 Vol. 28 (13): 228-231 [Abstract] ( 41 ) HTML (36 KB)  PDF  (0 KB)  ( 7 ) 232 Application effect of hypoglycemia high risk early warning score guidance nursing in hospitalized reducing the incidence of hypoglycemia WEN Wei Objective To explore the application effect of hypoglycemia high-risk early warning score guiding nursing in hospitalized reducing the incidence of hypoglycemia.Methods A total of 200 cases of DM inpatients treated in Ganzhou People′s Hospital in Jiangxi Province from January to December 2018 were selected as the research objects,and they were divided into the control group and the experimental group according to random number table method,100 cases in each group.The control group was given monitoring blood glucose according to the doctor′s advice and routine nursing scheme,while the experimental group was guided by hypoglycemia high-risk early warning score on the basis of the control group.The incidence of hypoglycemia,quality of life before and after intervention and nursing satisfaction were compared between the two groups.Results After intervention,the incidence of hypoglycemia in the experimental group(6.00%)was lower than that in the control group(26.00%),the difference was statistically significant(P＜0.05).After the intervention,the scores of social function,physical function,psychological function and material life of the experimental group were higher than those of the control group,the differences were statistically significant(P＜0.05).The nursing total satisfaction of the experimental group(92.00%)was higher than that of the control group(70.00%),the difference was statistically significant(P＜0.05).Conclusion The implementation of hypoglycemia risk early warning score guidance nursing in diabetic inpatients can effectively reduce the incidence of hypoglycemia in hospital,and improve the quality of life and nursing satisfaction of patients. 2021 Vol. 28 (13): 232-234 [Abstract] ( 35 ) HTML (30 KB)  PDF  (0 KB)  ( 6 ) 235 Evaluation on the effect of intensive infection nursing on reducing the occurrence of multi-drug resistant bacteria infection in patients with severe respiratory disease CHEN Gen-xiu；CHEN Guan-feng；DENG Wu-xiu；CHEN Shu-wen；WU Xiao-lan Objective To explore the effect of intensive infection nursing on reducing the incidence of multi-drug resistant bacteria infection in severe respiratory patients.Methods Eighty patients with severe respiratory illness admitted to the First Affiliated Hospital of Gannan Medical University from February 2018 to June 2020 were selected as the research objects,and were divided into the observation group(40 cases)and the control group(40 cases)according to the random number table method.The control group adopted anti-infection nursing and the observation group adopted intensive infection nursing.The infection and outcome of multi-drug resistant bacteria,the qualification rate of various indicators,and the total satisfaction of nursing were compared between the two groups.Results The infection rate of multi-drug-resistant bacteria in the observation group was lower than that in the control group,the difference was statistically significant(P＜0.05).There were no significant difference in the cure rate and mortality of multi-drug-resistant bacteria infection between the two groups(P＞0.05).The qualified rates of medical waste disposal,personal protective equipment,and hand hygiene of the observation group were higher than those of the control group,and the differences were statistically significant(P＜0.05).The observation group′s total nursing satisfaction was higher than that of the control group,the difference was statistically significant(P＜0.05).Conclusion Intensified infection nursing can reduce the incidence of multi-drug-resistant bacterial infections in patients with severe respiratory illness,and improve patients′overall satisfaction with nursing work.It is worthy of clinical promotion 2021 Vol. 28 (13): 235-237 [Abstract] ( 42 ) HTML (31 KB)  PDF  (0 KB)  ( 5 ) 238 Effect of optimized sedation and analgesia management on postoperative delirium in neurosurgical patients YANG Xi-mei；DENG Xin-zheng；WANG Jin-hua；CHEN Nuo Objective To explore the application effect of optimized sedation and analgesia management in postoperative delirium(POD)of neurosurgical patients.Methods A total of 82 patients who underwent neurosurgery in Dongguan Chang′an Hospital from October 2017 to December 2019 were selected as the research subjects.According to the random number table method,they were divided into optimization group(41 cases)and routine group(41 cases).The optimization group was given optimized sedation and analgesia management,while the routine group was given routine operation anesthesia and pain management.Duration of delirium,incidence of inadequate sedation,unplanned extubation,effectiveness of sedation(Ramsay sedation scale)analgesia(pain observation instrument [CPOT]scale for the intensive care unit [ICU]),incidence of POD,quality of care and satisfaction were compared between the two groups.Results The duration of delirivon,the incidence of improper sedation and unplanned extubation in the optimization group were lower than those in the routine group,and the differences were statistically significant(P＜0.05).Ramsay and CPOT scores in the optimization group at 10 and 30 min before operation were lower than those in the routine group,and the differences were statistically significant(P＜0.05).The incidence of POD in the optimization group was lower than that in the routine group,and the difference was statistically significant(P＜0.05).The score of nursing activity assessment scale(NAS)and the excellent and good rate of satisfaction in the optimization group were higher than those in the routine group,and the differences were statistically significant(P ＜0.05).Conclusion Optimization of sedation and analgesia management can effectively reduce the adverse events of sedation and analgesia in neurosurgery patients during perioperative period,improve the quality of nursing,reduce the incidence of POD,and have high safety. 2021 Vol. 28 (13): 238-241 [Abstract] ( 46 ) HTML (35 KB)  PDF  (0 KB)  ( 5 ) 242 Effect of detailed nursing on quality of life and complications in acute upper gastrointestinal hemorrhage patients with gastroscopic operation CHEN Bei;RAO Dan-xia;LI Pei-pei Objective To study the effect of detailed nursing on quality of life and complications in acute upper gastrointestinal hemorrhage patients with gastroscopic operation.Methods A total of 80 acute upper gastrointestinal hemorrhage patients with gastroscopic operation who were treated in Fuzhou First People′s Hospital,Jiangxi Province from January 2018 to January 2020 were selected and divided into the control group and the observation group according to random number table method,40 cases in each group.All patients underwent gastroscopic operation,the control group received routine nursing during treatment,and the observation group was given detailed nursing.The quality of life,anxiety,depression and complications of the two groups before nursing and intervention and after 5 days of nursing and intervention were compared.Results The scores of physical function,physical role,social function and mental health in the two groups were higher than those before nursing and intervention,and the scores of physical function,physical role,social function and mental health of the observation group were higher than those of the control group,the differences were statistically significant(P＜0.05).After 5 days of nursing and intervention,the self-rating anxiety,self-rating depression scale scores of both groups were lower than those before nursing and intervention,and the self-rating anxiety,self-rating depression scale scores of the observation group were lower than those of the control group,the differences were statistically significant(P＜0.05).Compared the total incidence of complications between the two groups,the difference was not statistically significant(P＞0.05).Conclusion Detailed nursing can promote the improvement of patients′quality of life after surgery,improve patients′anxiety and depression,and is worthy of popularization and use. 2021 Vol. 28 (13): 242-244-248 [Abstract] ( 47 ) HTML (32 KB)  PDF  (0 KB)  ( 7 ) 245 Application of diet guidance and family support nursing in nutritional improvement of chronic kidney disease patients with maintenance hemodialysis XU Feng-xia;CHNG Ling-ling;LIU Fang;LI Rui-hua;WU Wen-bin Objective To study the value of improving nutritional status of maintenance hemodialysis（MHD）patients with chronic kidney disease through nutritional guidance and family support care.Methods A total of 60 cases end stage renal disease patients who underwent regular MHD in Weifang Yidu Central Hospital in Shandong Province from January 1 to December 31,2019 were selected and divided into nutrition guidance group(group A)and non-nutrition guidance group(group B),30 cases in each group.The patients were followed up for 3 days using the method of dietary follow-up records.The dietary nutritional intake of all patients before guidance was analyzed in combination with the Dietary Guidelines for Chinese Residents(2016)and the Practical Guidelines for Nutritional Therapy of Chronic Kidney Disease(2018).Group A received dietary guidance through dietary counseling guidance and family support care while group B received routine care and health guidance,and the dietary nutritional intake of both groups was reassessed 12 weeks later by the same method.Results The dietary nutrient intake of group A after 12 weeks of intervention was improved compared with that before intervention,and the intake of calories,carbohydrates and fat was better than that of group B,with statistical differences(P＜0.05).Conclusion Dietary guidance and home care are of great significance in nutritional improvement of patients with chronic kidney disease on MHD. 2021 Vol. 28 (13): 245-248 [Abstract] ( 43 ) HTML (34 KB)  PDF  (0 KB)  ( 6 ) 249 Application value of high quality nursing in patients with intracranial aneurysm LIU Xiao-fen;LIU Zhen;JI Hong-ting;CHEN Xu Objective To study the application value of high quality nursing in patients with intracranial aneurysm.Methods Eighty patients with intracranial aneurysm treated in Shangrao People′s Hospital,Jiangxi Province from January 2017 to January 2020 were selected as research subjects,and were divided into the observation group(n=40)and the control group(n=40)by the random number table method.Routine nursing was applied to the control group,and high quality nursing was applied to the observation group.The compliance,nursing satisfaction,life quality score(SF-36)and complication occurrence in the two groups were compared.Results The total good rate of compliance after one week of intervention in the observation group(95.00%)was higher than that in the control group(82.50%),with statistical difference(P＜0.05).The total satisfaction of intervention after one week in the observation group(97.50%)was higher than that in the control group(75.00%),with statistical difference(P＜0.05).There were no statistically significant differences in the scores in terms of vitality,body pain,role emotional,role physical,physiological function,social function,emotional health or general health before the intervention in the two groups(P＞0.05).The scores in terms of vitality,body pain,role emotional,role physical,physiological function,social function,emotional health or general health after the intervention in the two groups were higher than those before the intervention,with statistical differences(P＜0.05).The scores in terms of vitality,body pain,role emotional,role physical,physiological function,social function,emotional health or general health after the intervention in the observation group were higher than those in the control group,with statistical differences(P＜0.05).There was no statistically significant difference in the total occurrence rate of complications in the two groups(P＞0.05).Conclusion High quality nursing after surgery for intracranial aneurysm can significantly improve the treatment compliance,nursing satisfaction and life quality of patients. 2021 Vol. 28 (13): 249-251-255 [Abstract] ( 37 ) HTML (32 KB)  PDF  (0 KB)  ( 7 ) 252 Effect of intensive psychological intervention on psychological status and family function of infertile patients during assisted reproductive technology treatment YE Se-dui Objective To explore the effect of intensive psychological intervention on psychological status and family function of infertile patients during assisted reproductive technology treatment.Methods A total of 88 infertile patients undergoing in vitro fertilization-embryo transplantation(IVF-ET)in Jiangmen Maternal and Child Health Care Hospital from August 2018 to August 2019 were selected as the research subjects.They were divided into control and observation groups according to the random number table method,with 44 patients in each group.The control group was given routine care,and the observation group received psychological intervention on this basis.The psychological status before and after the intervention and the pregnancy rate after the intervention were compared between the two groups.Results Before intervention,there were no significant differences in self-rating anxiety scale(SAS),self-rating depression scale(SDS)and family function scores between the two groups(P＞0.05).After the intervention,SAS and SDS scores of the two groups were lower than those before the intervention,and the scores of family function were higher than those before the intervention,and the differences were statistically significant(P＜0.05).After intervention,the scores of SAS and SDS in the observation group were lower than those in the control group,and the score of family function was higher than that in the control group,and the differences were statistically significant(P＜0.05).The pregnancy rate in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion Strengthening psychological intervention can significantly improve the psychological status and family function of patients with infertility during the treatment of assisted reproductive technology,and improve the pregnancy rate,which is worthy of clinical application. 2021 Vol. 28 (13): 252-255 [Abstract] ( 43 ) HTML (32 KB)  PDF  (0 KB)  ( 7 ) 256 Application of nursing intervention based on the concept of accelerated rehabilitation surgery in patients with gastric cancer undergoing radical gastrectomy LI Hua-juan Objective To explore the application effect of nursing intervention based on the concept of accelerated rehabilitation surgery(FTS)in patients with gastric cancer radical operation.Methods A total of 106 patients with gastric cancer undergoing radical gastrectomy in Maoming People′s Hospital in Guangdong Province from May 2018 to May 2020 were selected and divided into the control group(53 cases)and the observation group(53 cases)according to random number table method.The control group was given routine nursing,while the observation group was given FTS nursing intervention.The levels of nutritional status(serum albumin [ALB],inflammatory factors C-reactive protein[CRP],interleukin-6 [IL-6])before and after the intervention were compared between the two groups,and the incidence of complications was observed and compared between the two groups.Results The anal exhaust time,first time out of bed time and hospitalization time of the observation group were shorter than those of the control group,the differences were statistically significant(P＜0.05).There was no significant difference in nutritional status between the two groups before intervention(P＞0.05).After intervention,ALB in the observation group was higher than that in the control group,CRP and IL-6 in the observation group were lower than those in the control group,the differences were statistically significant(P＜0.05).The total incidence of complications in the observation group was lower than that in the control group,the difference was statistically significant(P＜0.05).Conclusion FTS nursing can improve the nutritional status of patients with gastric cancer radical operation,reduce the incidence of complications,so as to promote the rehabilitation of patients. 2021 Vol. 28 (13): 256-258-262 [Abstract] ( 41 ) HTML (31 KB)  PDF  (0 KB)  ( 7 ) 259 Observation on the effect of breast massage combined with ear acupoint pressing to promote lactation MAI Yan-ling Objective To explore the effect of breast massage combined with ear acupoint pressing to promote lactation.Methods A total of 359 parturients admitted to Foshan Gaoming District People′s Hospital from January to August 2019 were selected as the research objects.According to the odd and eveen number of inclusion order they were divided into the observation group(180 cases)and the control group(179 cases).The observation group used breast massage and ear acupoint pressing to promote lactation.The control group adopted routine post-delivery nursing measures.The lactation initiation time,48 h lactation volume,lactation effect on the 4th day after delivery,and the incidence of breast swelling in the two groups were compared.The effects of the two nursing methods on the lactation effect of the mother were compared.Results The lactation initiation time after delivery of the observation group was shorter than that of the control group,the difference was statistically significant(P＜0.05).The 24-hour lactation volume of the observation group was higher than that of the control group,the difference was statistically significant(P＜0.05).The breast swelling rate of the parturients in the observation group was lower than that of the control group on the 4th day after delivery,the difference was statistically significant(P＜0.05).The breast swelling degree of the parturients in the observation group was lower than that of the control group,the difference was statistically significant(P＜0.05).Conclusion Early breast massage combined with ear acupoint pressing after childbirth can shorten the lactation time,increase lactation and improve the effect of lactation,and can effectively prevent the incidence of maternal breast swelling,which is worthy of promotion. 2021 Vol. 28 (13): 259-262 [Abstract] ( 43 ) HTML (35 KB)  PDF  (0 KB)  ( 6 ) 263 Effect of comprehensive temperature-holding measures on perioperative body temperature and postoperative recovery in patients undergoing gynecological surgeries XIAO Ying;HUANG Wei;XU Chao;FENG Miao-qian Objective To explore the effect of comprehensive temperature-holding measures on perioperative body temperature,postoperative recovery and adverse events in patients undergoing gynecological surgeries.Methods Ninety-six patients undergoing gynecological surgeries admitted to Zhongshan Bo′ai Hospital,Guangdong Province from February 2019 to April 2020 were selected as the research subjects.They were divided into the control group(n=48)and the observation group(n=48)according to the random number table method.In the control group,routine heat preservation care was used,and in the observation group,comprehensive temperature-holding measure was adopted.The body temperature,postoperative recovery indicators,and total incidence of adverse events were compared between the two groups.Results There was no significant difference in body temperature between the two groups when entering the operation room(P＞0.05).The body temperature of the observation group was(36.48±0.47)℃at the end of the operation,higher than that of the control group of(36.12±0.35)℃,and the difference was statistically significant(P＜0.05).The time of postoperative spontaneous breathing,awakening,extubation,peristalsis,and hospital stay were(15.28±3.61),(24.63±4.13),(27.28±4.47)min,(14.28±3.62)h,(5.67±1.23)d,shorter than those of the control group of(19.04±3.33),(29.55±4.06),(34.34±4.69)min,(19.42±3.51)h,and(7.30±1.55)d,with statistical differences(P＜0.05).The total incidence of adverse events in the observation group was 4.16%,lower than that of the control group accounting for 18.75%,and the difference was statistically significant(P＜0.05).Conclusion Comprehensive temperature-holding measures can effectively maintain the perioperative body temperature of patients undergoing gynecological surgeries,shorten the time of awakening from anesthesia and extubation,reduce the incidence of adverse events such as chills and restlessness,and speed up the recovery process after surgery. 2021 Vol. 28 (13): 263-265-269 [Abstract] ( 38 ) HTML (32 KB)  PDF  (0 KB)  ( 7 ) 266 Application effect of predictive nursing intervention in tympanocentesis for secretory otitis media HE Jian-hua Objective To study application effect of predictive nursing intervention in tympanocentesis for secretory otitis media.Methods A total of 240 cases clinical data of secretory otitis media patients in Guangdong Province Zhongshan Xiaolan People′s Hospital from January 2018 to October 2020 were analyzed,which were divided into two group by different intervention,the control group(routine nursing)120 cases and detection group(routine nursing+predictive nursing intervention)120 cases,the treatment result,complication rate,pain symptoms score and daily living capacity score of two groups were compared.Results The total effect rate of detection group was higher than that of the control group,the total complication of detection group was lower than that of the control group,the pain symptoms score of detection group was lower than that of the control group,daily living capacity score was higher than that of the control group,the differences were statistically significant(P＜0.05).Conclusion Application of predictive nursing intervention in tympanocentesis for secretory otitis media could increase treatment result,decrease complication,improve pain and living quality,it is worth to be used. 2021 Vol. 28 (13): 266-269 [Abstract] ( 39 ) HTML (32 KB)  PDF  (0 KB)  ( 7 ) 270 Application effect of ″6A″ nursing management mode in endoscopy center CHEN Xin-mei;CHEN Bin-bin;LIN Yi-huan;HUANG Ming-yu Objective To explore the application effect of ″6A″ nursing management mode in endoscopy center.Methods A retrospective analysis of 33 cases of patients with endoscopic examination in Joint Logistics Support Force 900th Hospital from January to December 2018 was conducted and selected as the research objects(control group),and 40 cases of patients with endoscopic examination in Joint Logistics Support Force 900th Hospital from January to December 2019 were retrospectively analyzed(experimental group).The control group was given routine nursing management method,and the experimental group added with ″6A″ nursing management method.The nursing effect and nursing quality satisfaction of the two groups were compared.Results The score of endoscopic diagnosis and treatment in the experimental group was higher than that in the control group,the difference was statistically significant(P＜0.05).The comfort of endoscopy in the experimental group was higher than that in the control group,the total incidence of endoscopic complications in the experimental group was lower than that in the control group,the total satisfaction of nursing quality in the experimental group was higher than that in the control group,the differences were statistically significant(P＜0.05).Conclusion Adding ″6A″ nursing management method to patients undergoing endoscopic examination in endoscopy center can reduce the total incidence rate of endoscopic complications,improve the comfort of endoscopic examination,improve the endoscopic diagnosis and treatment effect score and nursing quality satisfaction. 2021 Vol. 28 (13): 270-272 [Abstract] ( 39 ) HTML (32 KB)  PDF  (0 KB)  ( 7 ) 273 Application of traditional Chinese medicine characteristic transitional care in stroke convalescent patients GUO Zhong-hua Traditional Chinese medicine characteristic transitional care refers to the traditional Chinese medicine concept,traditional Chinese medicine characteristic therapy and the new transitional care model combined application.In this paper,the characteristics,feasibility and necessity of traditional Chinese medicine characteristic transitional care were systematically expounded from the perspective of stroke convalescent treatment.The paper describes the specific application of this model in the treatment of stroke convalescent common complications,thinking deeply about the specific measures to further promote the traditional Chinese medicine characteristic continuity of nursing and the existing problems in the application of traditional Chinese medicine characteristic transitional care.Advocate the creation of high-quality traditional Chinese medicine characteristic continuous nursing model,realize the integrity of traditional Chinese medicine characteristic transitional care system,standardized operation,and ultimately improve the rehabilitation effect of patients and improve patients′satisfaction. 2021 Vol. 28 (13): 273-276 [Abstract] ( 43 ) HTML (38 KB)  PDF  (0 KB)  ( 6 )

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