腹主动脉旁淋巴引流区预防性放疗对中晚期合并盆腔淋巴结阳性宫颈癌的疗效

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Abstract Objective To investigate the effect of prophylaxis radiotherapy in para-aortic lymphatic drainage area on middle and advanced cervical cancer with positive pelvic lymph nodes.Methods A total of 81 patients with advanced cervical cancer with pelvic lymph node positive admitted to Jiangxi maternal and child health hospital from February 2015 to October 2017 were selected as the research subjects.According to random number table method,they were divided into control group(40 cases)and study group(41 cases).The control group received platinum-based chemotherapy,and the study group received prophylactic radiotherapy in the para-aortic lymphatic drainage area on this basis.The disease control rate,the incidence of adverse reactions of acute radiotherapy and chemotherapy and the survival rate were compared between two groups.Results The disease control rate in the study group was higher than that in the control group,and the difference was statistically significant(P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P＞0.05).The 2- and 3-year cumulative survival rate in the study group were higher than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion In the clinical treatment of middle and advanced cervical cancer complicated with positive pelvic lymph nodes,prophylactic radiotherapy in the para-aortic lymphatic drainage area has good clinical efficacy and high safety,which is worthy of promotion.

Key words： Lymph node Cervical cancer Para aortic lymphatic drainage area Prophylactic radiation

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	WANG Ya-nan
	ZENG Si-yuan
	ZHONG Mei-ling
	YUAN Jian-hui

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WANG Ya-nan,ZENG Si-yuan,ZHONG Mei-ling, et al. Therapeutic effect of prophylactic radiotherapy in para-aortic lymphatic drainage area for middle and advanced cervical cancer with positive pelvic lymph nodes[J]. 中国当代医药, 2021, 28(13): 54-56-60.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I13/54

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