|
|
Clinical effect of Rosuvastatin Calcium Tablets combined with Zhibitai in the treatment of hyperlipidemia |
TAN Bin1 WU Yi-jun2 YU Bo2 |
1.Department of Emergency,the Third People′s Hospital of Jingdezhen City,Jiangxi Province,Jingdezhen 333000,China;
2.Department of Cardiovascular Medicine,the Third People′s Hospital of Jingdezhen City,Jiangxi Province,Jingdezhen 333000,China |
|
|
Abstract Objective To analyze the value of Rosuvastatin Calcium Tablets combined with Zhibitai in the treatment of hyperlipidemia.Methods One hundred and twenty patients with hyperlipidemia treated in the Department of Emergency and Cardiovascular Medicine in the Third People′s Hospital of Jingdezhen City from September 2019 to August 2020 were selected as research subjects,and they were divided into the observation group(n=60)and the control group(n=60)by the random number method.Observation group was treated with Rosuvastatin Calcium Tablets combined with Zhibitai,and control group was treated with Rosuvastatin Calcium Tablets.The levels of total cholesterol(TC),triglyceride(TG),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C)before and after treatment and the total incidence of adverse reactions of the two groups were compared.Results Before treatment,there were no statistical significances in TC,TG,HDL-C and LDL-C between the two groups(P>0.05).The TC and TG of the two groups after treatment were lower than those before treatment,the differences were statistically significant(P<0.05).The TC and TG of observation group were lower than those in the control group after treatment,the differences were statistically significant(P<0.05).The HDL-C of the observation group after treatment was higher than that before treatment,LDL-C of observation group after treatment was lower than that before treatment,the differences were statistically significant(P<0.05).There were no significant differences in the HDL-C and LDL-C of control group before and after treatment(P>0.05).The LDL-C level in observation group after treatment was lower than that in the control group,and HDL-C level was higher than that in the control group,with statistical significances(P<0.05).There was no statistical significance in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Rosuvastatin Calcium Tablets combined with Zhibitai in the treatment of hyperlipidemia has a good effect,not only to improve the level of blood lipid,but also contribute to the stability of atherosclerotic plaque,and does not increase adverse reactions,which is worthy of clinical application.
|
|
|
|
|
[1] |
范燕宾,孙运.血脂康胶囊联合氨氯地平阿托伐他汀钙片治疗高血压合并冠心病的疗效及对炎性因子、血管内皮功能的影响[J].湖北科技学院学报(医学版),2020,34(2):124-126.
|
[2] |
翟晨辉,买热木古·阿布都热依木.氨氯地平阿托伐他汀钙片治疗高血压并高血脂的临床效果[J].中西医结合心血管病电子杂志,2020,8(10):75,89.
|
[3] |
谭斌.阿托伐他汀钙片联合脂必泰治疗冠心病合并高脂血症的效果[J].当代医学,2020,26(3):9-11.
|
[4] |
路峰,白玮炜,李利峰.血府逐瘀胶囊联合阿托伐他汀钙片治疗气滞血瘀型高脂血症的效果[J].中国当代医药,2020,27(14):75-78.
|
[5] |
刘俊,吴继雄.苯扎贝特片联合氨氯地平片治疗高血压合并血脂代谢紊乱患者的临床研究[J].中国临床药理学杂志,2020,36(3):243-245,253.
|
[6] |
江林泽,黄惠娟.比较苯磺酸左旋氨氯地平和瑞舒伐他汀钙片对高血压病合并高脂血症患者的治疗价值[J].临床医药文献电子杂志,2020,7(50):163-164.
|
[7] |
徐高阳,陈竞纬,徐伟.调脂颗粒结合瑞舒伐他汀钙片治疗高脂血症痰瘀互结证临床研究[J].国际中医中药杂志,2020,42(5):437-441.
|
[8] |
臧宇,米志宁,赵贵石.国产和进口阿托伐他汀钙片治疗原发性高脂血症的疗效观察及成本比较[J].中国医院用药评价与分析,2018,18(2):200-201,204.
|
[9] |
郭丽敏,林珊珊,龚晓娟,等.降脂灵片联合阿昔莫司治疗高脂血症的临床研究[J].现代药物与临床,2019,34(6):1673-1677.
|
[10] |
邱少波,肖蕾,郭丹,等.中药自拟方联合阿托伐他汀钙片治疗气虚痰瘀型高脂血症伴颈动脉斑块病人的临床疗效观察[J].中西医结合心脑血管病杂志,2019,17(15):2356-2358.
|
[11] |
林义轩.缬沙坦氨氯地平片联合阿托伐他汀钙片治疗高血压伴高血脂的效果及其对血管与心肌的保护作用[J].中西医结合心血管病电子杂志,2019,7(4):32-33.
|
[12] |
刘婵娟,徐文森,王静.阿托伐他汀钙片与血脂康治疗高脂血症的效果研究[J].中国病案,2018,19(10):92-94.
|
[13] |
孟亚星,张小玲,张灿,等.氟伐他汀缓释片治疗血脂异常合并高血压患者的疗效及安全性[J].安徽医学,2018,39(1):20-24.
|
[14] |
祁兴平,周利民,袁先琢,等.心脉通胶囊联合阿托伐他汀钙片治疗高血压病伴人血浆脂蛋白磷脂酶A2升高的疗效观察[J].中华全科医学,2019,17(7):1142-1145.
|
[15] |
何君杰,姜九,唐文锐,等.心舒宝片联合瑞舒伐他汀治疗高脂血症的临床研究[J].现代药物与临床,2019,34(3):672-676.
|
|
|
|