沙美特罗替卡松粉吸入剂联合无创正压通气治疗慢性阻塞性肺疾病合并呼吸衰竭的效果

Abstract
Figure/Table
References (19)
Related Citation (15)

Download: PDF (0 KB) HTML (38 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the efficacy and safety of Salmeterol Ticasone Powder Inhaler combined with noninvasive positive pressure ventilation(NPPV)in the treatment of chronic obstructive pulmonary disease(COPD)complicated with respiratory failure.Methods A total of 50 patients with COPD complicated with respiratory failure who were treated in the People′s Hospital in Lvyuan District of Changchun City from December 2018 to December 2019 were selected as the research subjects,and they were divided into study group and control group according to random number table method,with 25 cases in each group.Control group was treated with NPPV on the basis of conventional treatment.Patients in the study group received Salmeterol Ticasone Powder Inhaler combined with NPPV in addition to conventional treatment.The therapeutic effect of the two groups was compared and analyzed.Lung function before and after treatment was compared between the two groups.The total incidence of adverse reactions was compared between the two groups.Results The total effective rate in the study group was higher than that in the control group,and the difference was statistically significant(P＜0.05).Before treatment,there were no significant differences in the forced expiratory volume in the first second(FEV1),the ratio of FEV1 to forced vital capacity(FEV1%),the ratio of forced expiratory volume to forced vital capacity(FEV1/FVC)and the 6 min walk test(6MWT)between the two groups(P＞0.05).After treatment,FEV1,FEV1% and FEV1/FVC in the study group were higher than those in the control group,and 6MWT was longer than that in the control group,with statistically significant differences(P＜0.05).After treatment,the total incidence of adverse reactions in the study group was lower than that in the control group,with statistical significance(P＜0.05).Conclusion The use of Salmeterol Ticasone Powder Inhaler combined with NPPV in the treatment of COPD complicated with respiratory failure has outstanding clinical effect,which can significantly improve the pulmonary function indexes of patients,and significantly reduce the total incidence of clinical adverse reactions in patients after treatment.This program is safe and effective,which is worth promoting.

Key words： Salmeterol Ticasone Powder Inhaler Noninvasive positive pressure ventilation therapy Chronic obstructive pulmonary disease Respiratory failure Total effective rate of treatment Lung function

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	DU Lin
	ZHANG Xi-chang

Cite this article:

DU Lin,ZHANG Xi-chang. Effect of Salmeterol Ticasone Powder Inhaler combined with noninvasive positive pressure ventilation in the treatment of chronic obstructive pulmonary disease complicated with respiratory failure[J]. 中国当代医药, 2021, 28(13): 67-70.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I13/67

[1]	陈炜，洪永青，杨冬，等.HNPPV 联合舒利迭长期治疗稳定期重度COPD 合并呼吸衰竭患者的疗效及安全性[J].山东医药，2018，24（5）：7-9.
[2]	任英杰，郭彩霞.舒利迭联合无创通气对老年慢性阻塞性肺疾病合并呼吸衰竭患者肺功能和动脉血气的影响[J].中国老年学杂志，2017，36（10）：2440-2441.
[3]	钱俊峰，王洪源，徐芳，等.喘可治注射液联合舒利迭对老年COPD 急性加重期患者T 淋巴细胞亚群、炎症介质和凝血功能的影响[J].中国老年学杂志，2018，38（20）：72-74.
[4]	中华人民共和国卫生部.慢性阻塞性肺疾病诊断标准[J].国际呼吸杂志，2011，31（1）：1-2.
[5]	魏勇.探讨无创面罩机械通气（NPPV）治疗慢性阻塞性肺疾病（COPD）急性呼吸衰竭（ARF）的疗效[J].临床医药文献电子杂志，2019，4（14）：26.
[6]	赵丽格，闫佳强，李富东，等.COPD 稳定期患者以噻托溴铵联合舒利迭治疗的效果分析[J].国际医药卫生导报，2018，24（12）：1849-1851.
[8]	翟瑞玲，胡国新，何梦璋.舒利迭联合思力华治疗稳定期COPD 患者肺功能的临床效果[J].国际医药卫生导报，2018，24（16）：2537-2540.
[9]	尚丽，丁淑亚.舒利迭联合Bi PAP 治疗COPD 并呼吸衰竭的效果[J].深圳中西医结合杂志，2019，5（12）：98-99.
[10]	耿新普，刘荣，乐兆喜，等.沙美特罗替卡松粉吸入剂配合BIPAP 呼吸机对慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭的影响[J].临床肺科杂志，2018，23（7）：1343-1345.
[7]	Takamasa K，Satoshi M，Hiroshi S，et al.Clinical impact of episodic nocturnal hypercapnia and its treatment with noninvasive positive pressure ventilation in patients with stable advanced COPD[J].Int J Chron Obstruct Pulmon Dis，2018，5（13）：843-853.
[11]	赵波，刘峰，邹小广.茶碱缓释片联合沙美特罗替卡松粉吸入剂对慢性阻塞性肺疾病患者的疗效及对其生活质量的影响[J].中国医药，2018，13（5）：701-705.
[12]	袁一帆，袁楚樊，莫伟良.舒利迭联合无创通气对COPD并呼吸衰竭患者肺功能及动脉血气的影响[J].临床医学工程，2018，25（8）：115-116.
[13]	文小平，周光明，张志豪.无创通气与舒利迭联合治疗慢性阻塞性肺疾病呼吸衰竭的临床疗效[J].吉林医学，2018，39（2）：311-313.
[14]	葛燚.舒利迭、无创通气联合使用对老年急性加重期慢性阻塞性肺疾病并呼吸衰竭（Ⅱ型）的疗效分析[J].医药前沿，2018，8（22）：112.
[15]	胡晓凤，刘前桂，赵黎黎，等.沙美特罗替卡松粉吸入剂慢性阻塞性肺疾病患者血浆脑钠肽水平和健康状况的影响[J].湖南师范大学学报（医学版），2019，16（2）：102-105.
[16]	李晓苏，唐学义.沙美特罗替卡松粉联合噻托溴铵治疗慢性阻塞性肺疾病急性加重期的临床效果[J].药物评价研究，2020，43（2）：141-145.
[17]	黄天赐，罗冬珍，骆玉玲，等.舒利迭联合复方甲氧那明胶囊对COPD 稳定期患者肺功能及氧化应激反应的影响[J].中国医药科学，2019，9（21）：63-66.
[18]	张恩花.无创正压通气在慢性阻塞性肺疾病急性加重期合并急性左心功能不全的疗效分析[J].中国医药科学，2019，9（12）：235-239.
[19]	杜焰家，张伟强，温雅.慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者使用BiPAP 呼吸机通气的疗效观察[J].中国医药科学，2020，10（24）：208-210，244.