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2021 Vol. 28, No. 1
Published: 2021-01-08
4
Meta-analysis of the efficacy and safety of moxibustion in the treatment of cancer-related fatigue
HUANG Shuang-yan;YANG Liu;HAN Qiong;XUE Hui1 XU Li-ping
Objective
To systematily review the efficacy and safety of moxibustion for patients with cancer-related fatigue.
Methods
The computer retrieved nine databases,PubMed,CENTRAL,EMbase,CINAHL,Web of Science,Chinese biomedical literature database (CBM),China national knowledge infrastructure (CNKI),Weipu Chinese science and technology journal full-text database (VIP) and WanFang databases (WanFang),from the database to the published literature until July 26,2020.A randomized controlled trial (RCT) was collected on the efficacy of all moxibustion methods in patients with cancer-induced fatigue.Two researchers independently screened literature,extracted data and assessed the risk of bias of included studies.Then Meta-analysis was performed using Rev Man 5.3 software.
Results
A total of 18 studies involving 1312 patients were included.Meta-analysis showed that compared with the control group,moxibustion was more effective in improving patient fatigue (SMD=-1.30,95%CI[-1.44,-1.16],P＜0.000 01) and quality of life (SMD=1.39,95%CI[0.87,1.90],P＜0.000 01).The reported adverse reactions were mild burns and could be absorbed by themselves without treatment.
Conclusion
Moxibustion can effectively improve the cancer-related fatigue of patients,improve the quality of life of patients and it is safe and worthy of clinical application.However,limited by the number and quality of included studies,the above conclusions need to be verified by more high-quality studies.
2021 Vol. 28 (1): 4-9转15 [
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Effect of hypoxia inducible factor on the expression of related proteins in apoptotic pathway of nucleus pulposus cells in SD rats
LI Xu；YE Fang；LIU Yi-xiu；ZHAO Yu； XIE Xin；YANG Li-qun；TU Guan-jun
Objective
To explore the effect of hypoxia inducible factor-1α (HIF-1α) on the expression of related proteins in apoptotic pathway of nucleus pulposus cells in SD rats.
Methods
The nucleus pulposus cells of SD rats were primary cultured.The expression of HIF-1α was induced in different degrees in different conditions.Group A (hypoxia condition group): O
2
5%,CO
2
5%,N
2
90%;group B (over hypoxia condition group): O
2
2%,CO
2
5%,N
2
93%;group C(hypoxia and CoCl
2
treatment group): O
2
5%,CO
2
5%,N
2
90%;group D (hypoxia and CAY10585 treatment group): O
2
5%,CO
2
5%,N
2
90%.The apoptosis of each group was detected at the same time.Western Blot was used to detect the expression of HIF-1α,p53,Bax,caspase3 and Bcl-2 protein.The relationship between the changes of HIF-1α,p53,Bax,Bcl-2 and caspase3 and apoptosis rate was analyzed.
Results
HIF-1α protein expression was observed in all groups.The expression of HIF-1α protein in group B and group C was higher than that in group A,the expression of HIF-1α protein in group C was the highest,and the lowest in group D,the differences were statistically significant (P＜0.05).The expression trends of p53,Bax,and caspase3 proteins were the same,the highest in group C and higher than those in group A and B,the protein expression in group B was higher than that in group A,while the protein expression in group D was the lowest (P＜0.05).The expression trend of Bcl-2 and Bax was opposite,the lowest in group C,lower than that in group A,the highest in group D,higher than that in group A,the differences were statistically significant (P＜0.05).The results obtained by flow cytometry showed that the apoptotic rate of cells in group C was the highest,while that of group D was the lowest,there was a statistically significant difference between the two groups (P＜0.05).The changes of HIF-1α,p53,Bax,Bcl-2 and caspase3 were positively correlated with the apoptosis rate (P＜0.05).
Conclusion
The increase of HIF-1α expression can induce the apoptosis of nucleus pulposus cells.The expression of apoptosis related factors p53,Bax,Bcl-2 and caspase-3 is detected by HIF-1α expression in different degrees,which indicates the correlation between the expression of HIF-1α and the expression of apoptosis related proteins,thus reveals the effect of HIF-1α on the expression of apoptosis related factors in the mitochondrial apoptosis pathway of SD rat nucleus pulposus cell.
2021 Vol. 28 (1): 10-15 [
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Study on the role of STAT3 and its gene polymorphism on the genesis process of HPV16-induced cervical cancer
MO Xiao-liang ；QIN Gui-rong； JIANG Xiao-li； ZHOU Zhuo-lin ；YUAN Yuan
Objective
To explore the role of signal transducer and activator of transcription 3 (STAT3) and its gene polymorphism on the genesis process of human papillomavirus-16 (HPV16)-induced cervical cancer.
Methods
From January 2015 to December 2017,40 patients with chronic cervicitis,27 patients with cervical intraepithelial neoplasia and 17 patients with cervical cancer admitted to the First Affiliated Hospital of Guangxi Medical University were selected as the research objects,and sample data of 10 health examiners were collected.The polymerase chain reaction(PCR)-reverse dot hybridization and immunohistochemistry were used to detect HPV16 E6 protein,PCR method was used to detect STAT3 expression level,PCR-fragment length polymorphism (RFLP) was used to detect STAT3 gene C1697G polymorphism,and the results were compared and analyzed.
Results
The positive expression rate of E6 protein in patients with cervical cancer was higher than that in patients with chronic cervicitis and cervical intraepithelial neoplasia,and the difference was statistically significant (P＜0.05).The positive expression rate of STAT3 protein in patients with cervical cancer was higher than that in patients with chronic cervicitis and cervical intraepithelial neoplasia,and the difference was statistically significant (P＜0.05).There were statistically significant differences in the proportions of G/G and C/C among patients with cervical cancer,chronic cervicitis,and cervical intraepithelial neoplasia (P＜0.05).There was no statistically significant difference in the proportion of G/C among patients with cervical cancer,chronic cervicitis,and cervical intraepithelial neoplasia (P＞0.05).
Conclusion
STAT3 has close correlations with HPV16-induced cervical cancer,indicating that STAT3 and HPV16 expressions play an important role in the genesis and development of cervical cancer.
2021 Vol. 28 (1): 16-19转26 [
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Systematic evaluation of risk factors for peripheral neuropathy in Chinese population with type 2 diabetes mellitus
QIN Ming；SONG Yu-ling ；ZHANG Ting ；LIU Chang-mei
Objective
To investigate the risk factors associated with type 2 diabetic peripheral neuropathy in Chinese population through systematic evaluation.
Methods
The computer system was used to retrieve the related studies on risk factors for type 2 diabetic peripheral neuropathy in Chinese population in PubMed,EMbase,Chinese biomedical literature database(CBM),China national knowledge infrastructure (CNKI),Weipu Chinese science and technology journal full-text database (VIP) and WanFang databases (WanFang).The retrieval time limit was from January 2000 to February 2020,at the same time,references included in the literature were retrieved complementally.Two reviewers independently selected literatures based on inclusion and exclusion criteria,extracted data,and evaluated the quality using Rev Man 5.3 software for systematic review,using fixed-effect models or random-effect models to combine odds ratio(OR)values and 95%confidence intervals (CI) to analyze various relevant risk factors.Sensitivity analysis was used to evaluate the stability of the results and funnel plot was used to evaluate the publication bias of the literature.
Results
A total of 12 articles were included,with a total sample size of 7886 cases.There were 10 risk factors included in the analysis,including age,glycosylated hemoglobin,duration of diabetes,fasting blood glucose,2-hour postprandial blood glucose,systolic blood pressure,diastolic blood pressure,cholesterol,triglyceride and body mass index.The results showed that age,course of diabetes,glycosylated hemoglobin,fasting blood glucose were risk facters affecting the occurrence of diabetic peripheral neuropathy.
Conclusion
It is preliminarily determined that age,course of diabetes,glycosylated hemoglobin and fasting blood glucose are important independent risk factors affecting the occurrence of diabetic peripheral neuropathy.This study provides an important basis for early prevention and treatment of diabetic peripheral neuropathy.
2021 Vol. 28 (1): 20-26 [
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Application status and research progress on physical restraint
DU Yao-ting； LIU Zhi-qiang；GUAN Xi-hong
Physical restraint is currently a protective measure for patients with restlessness and unplanned extubation in clinical practice.This article summarized the current concepts of physical restraint at both home and abroad on the basis of referring to relevant domestic and foreign literatures,and used a knowledge database to query physical restraint tools to visualize the development process,advantages and disadvantages of restraint tools over time,and finally described the detailed clinical restraint steps,implementation principles,precautions and evaluation scales in combination of clinical research and our own experience,to provide reference for patients and medical workers.At last,the author proposes to design a new intelligent restraint product integrating restraint and monitoring functions by high intelligent technology to reduce the pain of restraining patients and the workload of medical staff.
2021 Vol. 28 (1): 27-30 [
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Research progress of NF-κB in lung cancer with air pollution
SHEN Jun-ting ；LEI Yu-jie
Air pollution is one of the main negative factors affecting human health.Long-term exposure to air pollution has been correlated with many respiratory disorders.Outdoor air pollution,classified as class Ⅰcarcinogen by the International Agency for Research on Cancer,contributes to the occurrence of lung cancer via various mechanisms.Nuclear factor kappa-light-chain-enhancer of activated B cells,also called NF-κB,is a protein complex that regulates DNA transcription.NF-κB is expressed in most cells and plays a significant role in the tumor,inflammation,autoimmune disease,development of the immune system,and viral infection.In recent years,researches on NF-κB have been increased gradually.This article will review the research progress on NF-κB in air pollution-related lung cancer.
2021 Vol. 28 (1): 31-34转49 [
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Application effect of changing body position in capsule endoscopy
Application effect of changing body position in capsule endoscopy
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SU Cheng-xia ；HU Yun-lian；ZHANG Qian； ZHANG Juan-li； NIE Lu
Objective
To explore the application effect of changing body position in capsule endoscopy.
Methods
Eighty patients who underwent capsule endoscopy from January to December 2018 were selected as the research objects.According to the sequence before and after the examination,40 patients were randomly divided into the control group and the observation group.The control group adopted the upright pusition to swallow the capsules,and observation group adopted the method of changing the body position.The time of capsule endoscopy passing through the esophagus,stomach and small intestine and the positive rate of diagnosis of esophagus,stomach and small intestine diseases were observed in the two groups.
Results
The duration of capsule endoscopy in the observation group was longer than that in the control group,and the difference was statistically significant (P＜0.05).There were no statistically significant differences between the two groups by comparing the time of capsule endoscopy in the stomach and small intestine (P＞0.05).The positive rate of gastric diseases in the observation group was higher than that in the control group,and the difference was statistically significant (P＜0.05).There were no statistically significant differences between the two groups in the positive rates of diagnosis of esophageal and intestinal diseases (P＞0.05).
Conclusion
The method of changing the body position can effectively improve the duration and amount of the capsule endoscope in the esophagus,and significantly improve the diagnosis rate of gastric diseases.
2021 Vol. 28 (1): 35-38 [
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Effect of high-dose interferon combined with operation on quality of life and prognosis in patients with malignant melanoma of skin
LI Qing-ren
Objective To investigate the effect of high-dose interferon combined with operation on quality of life and prognosis in patients with malignant melanoma of skin.Methods A total of 80 patients with malignant melanoma of skin who were treated in Dermatology Hospital of Jiangxi Province from January 2014 to January 2019 were divided into two groups according to the random number table method,with 40 cases in each group.The control group was treated with operation and low-dose interferon,and the observation group was treated with operation and high-dose interferon.The quality of life,survival rate and recurrence rate after 12 months were compared between the two groups.Results After 12 months of treatment,the scores of quality of life scale (SF-36) in observation group were higher than those in control group,the survival rate of the observation group was higher than that of the control group and the recurrence rate was lower than that in control group,and the differences were statistically significant (P＜0.05).Conclusion High-dose interferon combined with operation in treatment of patients with malignant melanoma of skin can increase quality of life,decrease postoperative recurrence rate and death rate,and promote prognosis.
2021 Vol. 28 (1): 39-41 [
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Effect observation of acupoint massage combined with tongue exercise in stroke patients with dysphagia
WANG Yue-xia； YU Jie-ming； ZENG Fei； CHENG Yu-ling； ZHAO Qi-fei
Objective
To explore the effect of acupoint massage combined with tongue exercise in stroke patients with dysphagia.
Methods
A total of 80 stroke patients with dysphagia admitted to Yunfu Hospital of Traditional Chinese Medicine from October 2018 to March 2020 were selected,and they were randomly divided into the control group and the study group,40 cases in each group.Both groups were given swallowing function training,the control group was given basic tongue exercise training and related psychological nursing,while the study group was given acupoint massage on the basis of basic tongue exercise training and related psychological nursing.The clinical effect,standard swallowing energy scale score and micronutrient assessment (MNA) rating of the two groups were observed and compared.
Results
The total effective rate of the study group was higher than that of the control group (P＜0.05).The standard swallowing energy scale scores of the study group at 2 and 4 weeks of treatment were lower than those of the control group (P＜0.05).The nutrition of the study group was better than that of the control group (P＜0.05).
Conclusion
Acupoint massage combined with tongue exercise can effectively improve the clinical treatment effect of stroke dysphagia,greatly improve the patients′ own nutritional level and promote the effective recovery of swallowing function of the body,with ideal clinical effect,which is worthy of clinical application and promotion.
2021 Vol. 28 (1): 42-45 [
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Comparison of the effect of Azithromycin and Roxithromycin in preventing acute attack of chronic obstructive pulmonary disease
CHEN Xiao-yun ；TANG Xiao-xiao
Objective
To compare the clinical effect of Azithromycin and Roxithromycin in preventing acute attack of chronic obstructive pulmonary disease.
Methods
A total of 80 patients with chronic obstructive pulmonary disease admitted to Affiliated Zhongshan Hospital of Dalian University from February 2019 to May 2020 were selected as the research objects,and they were divided into the control group and the observation group according to the random number table method,with 40 cases in each group.The observation group was treated with Roxithromycin,the control group was treated with Azithromycin,both groups were treated for 1 week.The changes of St George′s respiratory question(SGRQ) scores were compared before treatment,3 d after treatment and 1 week after treatment,inflammatory indexes(tumor necrosis factor-α[TNF-α],high-sensitivity C-reactive protein[hs-CRP]),pulmonary function indexes (percentage of forced expiratory volume in first second to forced vital capacity[FEV
1
%]and forced expiratory volume in one second/forced vital capacity[FEV
1
/FVC]) before and after treatment and the occurrence of adverse reactions were compared between the two groups.
Results
After treatment for 3 days and 1 week,the SGRQ scores in both groups were lower than those before treatment,and the SGRQ score of the observation group was lower than that of the control group,the differences were statistically significant (P＜0.05).After treatment,the levels of TNF-α and hs-CRP in both groups were lower than those before treatment,and the levels of TNF-α and hs-CRP in the observation group were lower than those in the control group,the differences were statistically significant (P＜0.05).After treatment,the levels of FEV
1
% and FEV
1
/FVC in both groups were higher than those before treatment,and the levels of FEV
1
% and FEV
1
/FVC in the observation group were higher than those in the control group,the differences were statistically significant(P＜0.05).The total incidence of gastrointestinal discomfort,rash,bitter mouth and tinnitus in the observation group was lower than that in the control group,the difference was statistically significant (P＜0.05).
Conclusion
The use of Roxithromycin to prevent the acute attack of chronic obstructive pulmonary disease can effectively improve the clinical symptoms of patients,reduce inflammation,improve lung function,with fewer adverse reactions and high safety.
2021 Vol. 28 (1): 46-49 [
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Clinical effect of high-flow and humidify oxygen therapy device in the treatment of chronic obstructive pulmonary disease combined with typeⅡrespiratory failure
ZHANG Li ；ZHOU Ji-hong； JIAO Xiao-qiang； YAO Kai-nan； LI Jue-hui； LI Zhu-yi
Objective
To study the clinical effect of high-flow and humidify oxygen therapy device in the treatment of chronic obstructive pulmonary disease（COPD）combined with type Ⅱrespiratory failure.
Methods
A total of 64 patients with COPD complicated with type Ⅱrespiratory failure who underwent clinical treatment in Hospital of Traditional Chinese Medicine Group of Bao′an District of Shenzhen City from January 2017 to December 2018 were selected as research objects.They were randomly divided into the treatment group and the control group,32 cases in each group.On the basis of conventional treatment,in the control group,low-flow oxygen was added,while in the treatment group,AIRV O
2
high-flow and humidify oxygen therapy device was added.The therapeutic effect rate,arterial blood gas level between two groups were compared.
Results
The treatment effectiveness rate of the treatment group was 78.13%,higher than that of the control group accounting for 53.13%,the difference was statistically significant (P＜0.05).After treatment,the level of arterial carbon dioxide partial pressure (PaCO
2
) in the treatment group was lower than that in the control group,with statistical significance (P＜0.05).
Conclusion
AIRV O
2
high-flow and humidify oxygen therapy device can reduce the partial pressure of PaCO
2
in blood gas analysis effectively,and worthy of spreading.
2021 Vol. 28 (1): 50-52 [
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Clinical effect of three vasoactive drugs in the treatment of esophageal variceal bleeding caused by cirrhosis
XI Yan
Objective
To investigate the clinical effect and adverse reactions of three vasoactive drugs,Octreotide,Somatostatin and Pituitrin in the treatment of esophageal and gastric variceal bleeding caused by cirrhosis,and to analyze the economy of different drug treatment regimen.
Methods
From July 2017 to December 2019,according to the three vasoactive drugs (Octreotide,Somatostatin and Pituitrin) 20 patients with esophageal and gastric variceal bleeding caused by cirrhosis treated in Lingyuan Central Hospital,Liaoning Province were selected respectively.The three vasoactive drugs corresponded to three different medication methods and different medication.The clinical effect,adverse reactions and drug economy of different drug use methods were compared and analyzed comprehensively.
Results
The total effective rates of clinical treatment in Somatostatin group and Octreotide group were higher than those in Pituitrin group,the differences were statistically significant (P＜0.05);during the treatment period,no significant adverse reactions were found in Somatostatin group and Octreotide group,while in Pituitrin group,abdominal pain and increased stool frequency were found in 7 patients,and 1 patient was intolerable due to pain during the treatment period,1 patient was found nausea and vomiting,1 patient was found dizziness,headaches.The drug costs of Somatostatin group and Octreotide group were higher than those of Pituitrin group,the differences were statistically significant (P＜0.05).
Conclusion
Octreotide and Somatostatin have better clinical effect and lower adverse reactions than Pituitrin in the clinical treatment of patients with esophageal and gastric variceal bleeding caused by cirrhosis，but Pituitrin has price advantage.It is suggested that the clinical treatment plan should be considered comprehensively according to the actual situation of patients.
2021 Vol. 28 (1): 53-55 [
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Effectiveness of application of epidemic surveillance in prevention and control of major infectious diseases
WANG Qian-qian
Objective
To explore the effectiveness and value of epidemic monitoring in the prevention and control of major infectious diseases.
Methods
Altogether 47 medical and health institutions in Donggang City were selected to analyze the situation before and after the epidemic surveillance strengthened from May 2017 to June 2019.The epidemic surveillance was not strengthened from May 2017 to May 2018,it was strengthened from June 2018 to June 2019.The problems existing in the management of epidemic situation were analyzed before and after the strengthening of epidemic monitoring.The targeted and comprehensive epidemic monitoring work was carried out so as to solve the existing problems.A comparison of various indexes was performed before and after the epidemic monitoring,including the reporting rate of major epidemic situation,the accuracy and completeness in filling out the infectious disease reports,the timeliness from diagnosis to reporting and the satisfactory rate of medical and health institutions.
Results
The reporting rate of major infectious diseases was 97.87% after strengthening of epidemic surveillance,which was higher than 72.34%prior to the strengthening of epidemic surveillance,with statistical difference (χ
2
=12.274,P＜0.05).The accuracy and completeness rate in filling out the infectious disease reports were 93.62% and 91.49% after the strengthening of epidemic monitoring,which were higher than 63.83% and 70.21% prior to the strengthening of epidemic monitoring,with statistical differences (χ
2
=14.982,P＜0.05;χ
2
=10.134,P＜0.05),respectively.The timeliness from diagnosis to reporting of the epidemic situation was 95.74% after the improvement of epidemic monitoring,which was higher than 57.45% before the strengthening of epidemic monitoring (χ
2
=18.612,P＜0.05).The satisfaction rate of medical and health institutions was 97.87% after the improvement of epidemic monitoring,which was higher than 85.11% before the strengthening of epidemic monitoring (χ
2
=6.116,P＜0.05).
Conclusion
Strengthening the epidemic monitoring has a positive effect on the prevention and control of infectious diseases.It can reduce the occurrence of infectious diseases,improve the timeliness and accuracy of reporting infectious diseases,provide a reliable guarantee for the prevention and control of major infectious diseases and boost the quality and efficiency of infectious disease prevention and control,which is worthy of promotion and application.
2021 Vol. 28 (1): 56-58转62 [
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Comparison of clinical effect and safety of Duloxetine and Escitalopram in the treatment of patients with depression
ZHANG Jin
Objective
To compare the clinical effect and safety of Duloxetine and Escitalopram in the treatment of patients with depression,so as to provide reference for the treatment of psychiatric depression.
Methods
A total of 120 patients with depression admitted to the Department of Psychiatric of Jinzhou Kangning Hospital from February 2018 to February 2020 were selected as the research objects,and the patients were divided into the control group and the observation group by the random number table method,with 60 patients in each group.Patients in the control group were treated with Escitalopram,while patients in the observation group were treated with Duloxetine.The prognostic outcomes of the two groups were compared,including the total effective rate of treatment,the total incidence of adverse reactions and the depression score.
Results
The total effective rate of patients in the observation group was higher than that in the control group,and the difference was statistically significant (P＜0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,with statistically significant difference (P＜0.05).There was no significant difference in depression score between the two groups before treatment (P＞0.05).At 1,2,4,and 8 weeks after treatment,the depression scores of patients in the observation group were lower than those in the control group,with statistically significant differences (P＜0.05).
Conclusion
Both Duloxetine and Escitalopram can be used in the treatment of depression.However,compared with the treatment effect,safety and symptom improvement,Duloxetine has obvious advantages and is the preferred therapeutic drug.
2021 Vol. 28 (1): 59-62 [
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Reasearch on the role of continuous rehabilitation management on prevention of falls in elderly patients with mild cognitive impairment
WANG Jun-li
Objective
To investigate the role of continuous rehabilitation management in preventing falls in elderly patients with mild cognitive impairment.
Methods
A total of 52 elderly patients with mild cognitive impairment admitted to Fuxin Central Hospital of Liaoning Province from February 2018 to July 2019 were selected as the research subjects.According to the random number table method,the patients were divided into control group and observation group,with 26 cases in each group.The control group underwent routine management,and the observation group underwent continuous rehabilitation management.Two groups were intervened continuously for 6 months after discharge to observe the compliance,the incidence of falls and the ability to take care of themselves.
Results
After 6 months of different management,the incidence of falls in observation group was lower than that in control group,the compliance in the observation group was higher than that in the control group,and the differences were statistically significant (P＜0.05).The observation group′s self-care ability scores at 1 month,3 months and 6 months were lower than those of the control group,and the differences were statistically significant (P＜0.05).
Conclusion
Continuous rehabilitation management can effectively prevent or reduce the incidence of falls in elderly and young patients with cognitive impairment,maximize patient compliance,and improve their self-care ability.
2021 Vol. 28 (1): 63-66 [
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Clinical effect of Tacrolimus Ointment in the treatment of photosensitive skin diseases
LIU Quan-wei
Objective
To explore the clinical effect of Tacrolimus ointment in the treatment of photosensitive skin diseases.
Methods
A total of 100 patients with photosensitive skin diseases admitted to Shenyang Seventh People′s Hospital from January 2018 to December 2019 were selected as the research objects,according to the random number table method,they were divided into the control group (50 cases) and the observation group (50 cases).The control group was treated with conventional treatment of Compound Zinc Oxide Ointment or Hirudoid Ointment externally,the observation group was treated with Tacrolimus Ointment externally.The treatment effect,the occurrence of adverse drug reactions and the conditions of skin lesions,itchy skin and dermatology life quality index (DLQI) scores of patients before and after treatment were compared between the two groups.
Results
In the observation group,the total effective rate of treatment was higher than that in the control group,and the total incidence of adverse reactions was lower than that in the control group,the differences were statistically significant (P＜0.05).After treatment,the scores of skin lesion condition,itchy skin condition and DLQI in the two groups were lower than those before treatment,and the above scores in the observation group were lower than those in the control group,the differences were statistically significant (P＜0.05).
Conclusion
Patients with photosensitive skin diseases treated with Tacrolimus Ointment can obtain good therapeutic effects,relieve skin itching,improve skin lesions,and improve the quality of life of patients,and the adverse reactions of patients are fewer,the safety is good.
2021 Vol. 28 (1): 67-70 [
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Relationship study between the expression and polymorphism of NLRP3 inflammatory bodies and the level of Caspase-1 and the degree of coronary lesions in patients with acute coronary syndrome
WU Wei ；WANG Xiao-ping； SUN Lin； NI Qing； SHAO Bing ；ZHANG Jing； TIAN Xin
Objective
To study the relationship between the expression and polymorphism of inflammatory bodies of Nod like receptor protein 3 (NLRP3) and the level of Caspase-1 and the degree of coronary lesions in patients with acute coronary syndrome (ACS).
Methods
From January 2018 to may 2019,150 patients with ACS diagnosed clinically in the Department of Cardiology of the Second Affiliated Hospital of Shenyang Medical College were selected as the experimental group,50 patients suspected with coronary heart disease admitted to hospital during the same period but who underwent negative coronary angiography examination were selected as the control group.The peripheral blood was collected and the rs10754558 polymorphism of NLRP3 gene was detected.The serum was isolated and the activity index of inflammatory body was measured.Coronary angiography was performed at the same time.The expression levels of NLPR3 and Caspase-1 were compared between the two groups.According to the results of coronary angiography,the expression levels of NLPR3 and Caspase-1 and the Gensini scores of different coronary lesions were recorded.The coronary lesions of different NLRP3 genotypes were observed,and the relationship between the expression and polymorphism of NLRP3 and the level of Caspase-1 and the degree of coronary lesions were analyzed.
Results
The expression levels of NLPR3 and Caspase-1 in the experimental group were higher than those in the control group (P＜0.05).In the experimental group,the expression levels of NLPR3,Caspase-1 and Gensini score in the patients with three vessel lesions were higher than those in the patients with two vessel lesions and single vessel lesion,the expression levels of NLPR3,Caspase-1 and Gensini score in patients with two vessel lesions were higher than those in patients with single vessel lesion,the differences were statistically significant (P＜0.05).Pearson correlation analysis showed that NLPR3 expression level was positively correlated with Caspase-1 expression level and Gensini score (r=0.714,0.781,P＜0.05).Among the rs10754558 genotypes of NLRP3 gene in the experimental group,44 cases (29.33%)were CC genotype,46 cases (30.67%)were GG genotype,and 60 cases(40.00%) were GC genotype.In the rs10754558 genotypes of NLRP3 gene in the control group,40 cases (80.00%) were CC genotype,4 cases (8.00%) were GG genotype and 6 cases (12.00%) were GC genotype.The proportions of GG genotype and GC genotype in NLRP3 gene of the experimental group were higher than those of control group,and the proportion of CC genotype in NLRP3 gene of the experimental group was lower than that of control group,the differences were statistically significant (P＜0.05).In the experimental group,the three branches lesions were mostly seen in the GG and GC types of NLPR3.
Conclusion
The expression of NLPR3 in ACS patients is positively correlated with Caspase-1 expression level and Gensini score.The increase of allele g at rs10754558 of NLRP3 gene can increase the activity of inflammatory bodies,indicating the severity of coronary lesions and poor prognosis.
2021 Vol. 28 (1): 71-74 [
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Analysis of correlative influencing factors of CAD
WANG Hui；ZHANG Kui；WANG Yang
Objective
To investigate the factors influencing of coronary artery disease (CAD).
Methods
A total of 1086 consecutive patients who were enrolled in the Shihezi Municipal People′s Hospital from January 2018 to December 2019 were selected as subjects.In accordance with the World Health Organization (WHO) diagnosis standard of CAD,they were divided into CAD group (666 cases) and non-CAD group (420 cases).General information on all patients was collected.The biochemical characteristics were examined,and multiple factors were analyzed by Logistic regression analysis.
Results
Unifactor analysis showed that the proportion of male,age,the proportion of smoking,the proportion of hypertension,the proportion of diabetes and uric acid level in the CAD group were higher than those in the non-CAD group,and the high-density lipoprotein cholesterol level was lower than that in the non-CAD group,with statistically significant differences (P＜0.05).The results of multivariate Logistic regression analysis showed that male (β=0.452,OR=1.571,95%CI=1.048-2.356),advanced age (β=0.053,OR=1.055,95%CI=1.041-1.068),smoking (β=0.697,OR=2.007,95%CI=1.359-2.963),diabetes (β=0.618,OR=1.856,95%CI=1.352-2.548),high uric acid (β=0.002,OR=1.002,95%CI=1.000-1.003) were the risk factors for CAD (P＜0.05),high density lipoprotein cholesterol (β=-0.708,OR=0.493,95%CI=0.333-0.730) was the protection factor for CAD (P＜0.05).
Conclusion
The present study indicates that high uric acid,being male,advanced age,smoking,and diabetes may be risk factors for CAD,while high density lipoprotein cholesterol may be a protective factor for CAD.
2021 Vol. 28 (1): 75-77 [
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44
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78
Effect of Lipidetine combined with Atorvastatin in the treatment of coronary heart disease with hyperlipidemia
ZHANG Cheng-long
Objective
To investigate the effect of Lipopitride combined with Atorvastatin in the treatment of patients with coronary heart disease with hyperlipidemia.
Methods
A total of 103 patients with coronary heart disease and hyperlipidemia admitted to People′s Hospital of Yunyang District in Shiyan City from July 2018 to July 2019 were selected,and they were divided into Atorvastatin group (n=51) and combined treatment group (n=52) by random digital table method.Atorvastatin group was treated with Atorvastatin orally in the basic treatment,the combined treatment group was treated with Lipopitride combined with Atorvastatin.The control conditions of total cholesterol (TC),triacylglycerol(TG),low-density lipoprotein cholesterol (LDL-C),high-density lipoprotein cholesterol (HDL-C) were compared between the two groups,the levels of hypersensitive C reactive protein (hs-CRP) before and after treatment were measured and compared between the two groups,the adverse reactions of patients during medication were observed.
Results
The TC、TG、LDL-C control compliance rates in the combined treatment group were higher than those in the atorvastatin group (P＜0.05).There was no significant difference in HDL-C control compliance rate between the two groups(P＞0.05).After treatment,the hs-CRP of both groups was lower than that before treatment,and the hs-CRP of the combined treatment group was lower than that of Atorvastatin group (P＜0.05).The total adverse reaction rate in the combined treatment group was 5.77%,which was lower than 19.61% in the Atorvastatin group (P＜0.05).
Conclusion
Patients with coronary heart disease and hyperlipidemia treated with Lipopitride combined with Atorvastatin can play a better lipid-lowering effect,improve their blood lipid indicators,and reduce hs-CRP levels.
2021 Vol. 28 (1): 78-80 [
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64
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Effect comparison of Clopidogrel and Aspirin in the treatment of coronary heart disease
QIU Hong-wei； CHEN Xiao-chun ；LIANG Zhi-hao
Objective
To compare the effect of Clopidogrel and Aspirin in the treatment of coronary heart disease.
Methods
A retrospective analysis was conducted on 100 patients with coronary heart disease treated in Yangjiang Traditional Chinese Medicine Hospital from January 2018 to January 2020.According to the treatment drugs,they were divided into two groups: Clopidogrel group (n=50) and Aspirin group (n=50).The clinical efficacy,coagulation functions and adverse reactions of the two groups were statistically analyzed.
Results
The total effective rate of the Clopidogrel group was 94.0% (47/50),which was higher than the Aspirin group of 62.0% (31/50),the difference was statistically significant (P＜0.05).Comparison of coagulation function indexes before treatment between the two groups showed no statistically significant difference (P＞0.05).After treatment,the platelet aggregation rates of the two groups were lower than those before treatment,and the activated partial thrombin time (APTT) and prothrombin time (PT) were shorter than those before treatment,with statistically significant differences (P＜0.05).The platelet aggregation rate of Clopidogrel group after treatment was lower than that of Aspirin group,and APTT and PT were shorter than those of Aspirin group,with statistically significant differences (P＜0.05).The total incidence of adverse reactions in the Clopidogrel group was 8.0% (4/50),which was lower than 36.0% (18/50) in the Aspirin group,with statistically significant difference (P＜0.05).
Conclusion
The clinical effect of Clopidogrel in patients with coronary heart disease is better than Aspirin,with fewer adverse reactions,which is worthy of clinical application.
2021 Vol. 28 (1): 81-83 [
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49
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84
Diagnostic value of coronary artery calcification detection combined with treadmill exercise test examination in coronary heart disease
ZHANG Gang
Objective
To investigate the diagnostic value of coronary artery calcification detection combined with treadmill exercise test examination in coronary heart disease.
Methods
The clinical data of 249 patients with coronary heart disease from January 2017 to June 2019 in Liaoyang Central Hospital were retrospectively collected.All patients underwent coronary artery calcification score (CACS) and treadmill exercise test (TET),and coronary angiography(CAG) was used as the diagnosis criteria to compare diagnosis results.
Results
The sensitivity,specificity and accuracy of CACS+TET examination were higher than those of two single examinations,the differences were statistically significant (P＜0.05).The coincidence rates of detection of coronary artery stenosis by CACS+TET were higher than those of single examination,the differences were statistically significant (P＜0.05).
Conclusion
CACS combined with TET can improve the diagnostic sensitivity,specificity and accuracy for coronary heart disease,and has high clinical value.
2021 Vol. 28 (1): 84-86 [
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52
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Application efficacy of hemodialysis therapy in chronic renal failure and its influence on renal function
LIN Zhong-jun；YANG Yong-an；SU Yong；LIU Jiang； LIU Yong
Objective
To explore the effect of hemodialysis therapy on the clinical efficacy and renal function of patients with chronic renal failure.
Methods
A total of 102 patients with chronic renal failure who were admitted to the Department of Nephrology of People′s Hospital of Yangjiang from October 2017 to October 2019 were selected,they were divided into two groups according to the random number table method,with 51 cases in each group.The control group used conventional treatment,and the study group combined hemodialysis therapy on the basis of conventional treatment.The application effects of different treatment methods,changes in various indicators of renal function and the incidence of adverse reactions were compared between the two groups.
Results
The total effective rate of clinical treatment in the study group was higher than that in the control group,and the difference was statistically significant (P＜0.05);after treatment,the glomerular filtration,blood urea nitrogen,and serum creatinine levels of the study group were lower than than those in the control group,and the differences were statistically significant (P＜0.05).The total incidence of adverse reactions in the study group was lower than that in the control group,and the difference was statistically significant (P＜0.05).
Conclusion
Conventional therapy combined with hemodialysis therapy significantly improves the cure rate of patients with chronic renal failure and relieves renal function.The prognosis of patients is better,and it can be widely used clinically.
2021 Vol. 28 (1): 87-89 [
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42
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Effect of different hemodialysis regimens on cardiac function in uremia patients with hemodialysis
GUAN Xing-ye
Objective
To investigate the effect of different hemodialysis regimens on cardiac function in uremia patients with hemodialysis.
Methods
A total of 86 patients with uremia who were admitted to Liaoyang Infectious Diseases Hospital from February to December 2019 were selected as the research subjects.All selected cases were divided into two groups according to random number method,with 43 cases in each group.Two groups were given basic treatment,the patients in control group were treated with hemodialysis,and the patients in observation group were treated with hemodialysis and hemoperfusion,with 1 month of treatment in two groups.The cardiac function,renal function,levels of serum indexes and quality of life in the two groups were compared.
Results
After 1 month of treatment,the left ventricular end diastolic volume (LVEDV) and left ventricular end systolic volume (LVESV) levels of the two groups were lower than those before treatment,and the left ventricular ejection fraction (LVEF) levels of the two groups were higher than those before treatment,the differences were statistically significant (P＜0.05);the levels of serum interleukin-6(IL-6),Angiotensin Ⅱ (Ang-Ⅱ) and brain natriuretic peptide (BNP) in the two groups were lower than those before treatment,the differences were statistically significant (P＜0.05);the levels of serum creatinine (SCr) and urea nitrogen(BUN) in the two groups were lower than those before treatment,the differences were statistically significant (P＜0.05);the two groups′ quality of life comprehensive assessment questionnaire (GQOLI-74) scores were higher than those before the treatment,the differences were statistically significant (P ＜0.05).After 1 month of treatment,the levels of LVEDV and LVESV in the observation group were lower than those in the control group,and the LVEF level was higher than that in the control group,the differences were statistically significant (P＜0.05);the levels of IL-6,Ang-Ⅱand BNP in the observation group were lower than those in the control group group,the differences were statistically significant(P＜0.05);the levels of SCr and BUN in the observation group were lower than those of the control group,and the differences were statistically significant (P＜0.05);the GQOLI-74 scores of the observation group were higher than those of the control group,and the differences were statistically significant significance (P＜0.05).
Conclusion
Single hemodialysis or combined with hemoperfusion in patients with uremia can effectively decrease the levels of inflammatory factors,improve cardiac function and renal function,increase quality of life,and hemodialysis combined with hemoperfusion has better efficacy.
2021 Vol. 28 (1): 90-93 [
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50
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Effect of Low Molecular Weight Heparin on balance of coagulation and fibrinolysis in patients undergoing hemodialysis for uremia
CHEN Yi-chen
Objective
To investigate the effect of low molecular weight heparin on balance of coagulation and fibrinolysis in patients undergoing hemodialysis for uremia.
Methods
A total of 124 patients with uremia who were treated with hemodialysis from January 2015 to January 2020 in Ansteel Group General Hospital were selected.They were divided into control group (62 cases) and observation group (62 cases) by random number table method.The control group received unfractionated Heparin anticoagulation therapy,and the observation group received Low Molecular Heparin anticoagulation therapy.Coagulation function indexes and occurrence of adverse hemodialysis events were compared between the two groups.
Results
After intervention,levels of D-dimer,platelet count,activated partial thromboplastin time,prothrombin time and fibrinogen in the observation group were lower than those in the control group,the differences were statistically significant (P＜0.05).The total incidence of instrument or conduit coagulation in the observation group was lower than that in the control group,the difference was statistically significant (P＜0.05).
Conclusion
Compared with unfractionated Heparin,Low Molecular Weight Heparin anticoagulation has a prominent effect on the balance of coagulation and fibrinolysis in uremic hemodialysis patients,and can effectively alleviate hypercoagulability and reduce the risk of hemodialysis failure.
2021 Vol. 28 (1): 94-96 [
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43
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Application effect of intraoperative compound heat preservation nursing model in general surgery patients
GUO Yan-zi
Objective To explore the application effect of intraoperative compound heat preservation nursing model in general surgery patients.Methods A total of 120 patients with general surgery who were admitted to the First People′s Hospital of Fuzhou from February 2018 to March 2020 were selected as research objects.According to the different nursing method,they were divided into the control group (60 cases) and the observation group (60 cases).Patients in the control group received routine nursing,and in the observation group,routine nursing combined with compound heat preservation nursing was used.The perioperative temperature,postoperative infection,comfort and nursing satisfaction scores were compared between the two groups.Results The intraoperative 0.5 h and postoperative body temperatures of the observation group were higher than those of the control group,the differences were statistically significant (P＜0.05).The incidence rates of intraoperative hypothermia and postoperative infection (1.67%,3.33%) in the observation group were lower than those in the control group (16.67%,15.00%),and the differences were statistically significant (P＜0.05).The comfort and nursing satisfaction scores of the observation group were higher than those of the control group,and the differences were statistically significant (P＜0.05).Conclusion The application of intraoperative compound thermal insulation nursing mode in general surgery patients can maintain the patient′s body temperature stability,reduce the incidence of intraoperative hypothermia and postoperative infection,and improve patient comfort and nursing satisfaction.
2021 Vol. 28 (1): 97-99转103 [
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Application effect of peanut rotation skeletonization on the vascular pedicle of the upper thyroid to protect the superior laryngeal nerve
LI Gang； LI Yue-xiang； HUANG You-fang； ZHANG Jian； DING Yong； XIAO Yan； LIU Qi-lin； WANG Tang-xin
Objective
To explore the application effect of peanut rotation skeletalization on the vascular pedicle of the upper thyroid to protect the superior laryngeal nerve.
Methods
A total of 52 patients who underwent thyroid surgery in the Department of Otorhinolaryngology Head and Neck Surgery,Xingguo People′s Hospital from January 2019 to February 2020 were selected as the research objects.According to the random number table method,they were divided into the control group and the experimental group,with 26 cases in each group.The control group received steroid protection;the experimental group received peanut rotation protection.The incidence of supralaryngeal nerve function damage,supralaryngeal nerve function recovery time,complication rate,quality of life score before and after treatment and therapeutic satisfaction were compared between the two groups.
Results
The incidence of supralaryngeal nerve damage in the experimental group was lower than that of the control group,the recovery time of supralaryngeal nerve function was shorter that of the control group,the differences were statistically significant (P＜0.05).The total incidence of complications in the experimental group was lower than that in the control group,the difference was statistically significant (P＜0.05).Before treatment,there were no statistically significant differences in the quality of life scores of the two groups (P＞0.05).After treatment,the quality of life scores of the experimental group were higher than those of the control group,the total therapeutic satisfaction was higher than that of the control group,the differences were statistically significant (P＜0.05).
Conclusion
The application of peanut rotation skeletalization in the vascular pedicle of the upper thyroid to protect the superior laryngeal nerve obtains good effect and high safety.
2021 Vol. 28 (1): 100-103 [
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Clinical effect of laparoscopy in the treatment of complex difficult gallbladder stones
LI Ming； HU Zhen-tao； ZHANG Zhen-ming； XU Wen-shan； YAN Peng TU Song
Objective
To explore the clinical effect of laparoscopy in the treatment of complex difficult cholelithiasis.
Methods
A total of 378 patients with complex difficult cholelithiasis in Zhangye People′s Hospital of Hexi University from January 2012 and December 2019 were selected and divided into experimental group (192 cases) and control group (186 cases) according to random number table method.Experimental group used laparoscopy cholecystectomy,the control group used open cholecystectomy.The operative time and biliary tract injury,choledocholithiasis residue,incidence of incision infection,intraoperative bleeding volume,postoperative hospitalization time and total incidence of postoperative complications were compared between the two groups.
Results
The intraoperative bleeding in the experimental group was less than that in the control group,postoperative hospitalization time was shorter than that in the control group,and total incidence of postoperative complications was lower than that in the control group (P＜0.05).There were no significant differences in the operation time and the incidence of biliary tract injury,choledocholithiasis residue and incision infection between the two groups (P＜0.05).
Conclusion
Compared with open cholecystectomy,laparoscopic cholecystectomy for complex difficult cholelithiasis has lower intraoperative bleeding,postoperative hospitalization time and total incidence of postoperative complications,which is worthy of clinical promotion.
2021 Vol. 28 (1): 104-107 [
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Comparison of the clinical effect of open hernia repair and laparoscopic hernia repair treating initial inguinal hernia of adult
ZHU Yi-sheng； PENG Chuan-lin； LI Dan
Objective
To explore the clinical effect of open hernia repair and laparoscopic hernia repair treating initial inguinal hernia of adult.
Methods
The clinical data of 64 patients with initial inguinal hernia of adult who were admitted to Suzhou First People′s Hospital from January 2017 to December 2018 were retrospectively analyzed.According to the different treatment method,they were divided into group A (34 cases) and group B (30 cases),group A underwent open small incision tension-free hernia repair group (Lichtenstein operation),group B underwent laparoscopic hernia repair group (TAPP operation).The intraoperative bleeding,hospital stay,postoperative pain duration,postoperative anal exhaust time and hospitalization expenses were observed and compared between the two groups.
Results
The operation time of group A was shorter than that of group B,the difference was statistically significant (P＜0.05).The blood loss in group A was more than that in group B,the difference was statistically significant (P＜0.05).The postoperative anal exhaust time of group A was shorter than that of group B,the difference was statistically significant (P＜0.05).The length of stay in group A was longer than that in group B,the difference was statistically significant (P＜0.05).The hospitalization expenses in group A was less than that in group B,the difference was statistically significant (P＜0.05).
Conclusion
Laparoscopic hernia repair and open tension-free hernia repair are safe and effective methods for the treatment of inguinal femoral hernia,but laparoscopic hernia repair will make patients bear high cost of medical treatment,so we should consider the operation plan comprehensively according to the patients′ various conditions and achieve individualized treatment.
2021 Vol. 28 (1): 108-110 [
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53
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Effect comparison of arthroscopic limited and extensive debridement in the treatment of knee osteoarthritis
SONG Wei-hong； XUAN Dong； XIAO Jun-feng
Objective
To compare the effect of arthroscopic limited and extensive debridement in the treatment of knee osteoarthritis.
Methods
A total of 80 patients with knee osteoarthritis admitted to Central People′s Hospital of Zhanjiang City in Guangdong Province from January 2019 to January 2020 were selected as the research objects and divided into the control group and the observation group according to the random number table method,with 40 cases in each group.The control group was treated with extensive debridement under arthroscopy,and the observation group was treated with limited debridement under arthroscopy.The perioperative related indicators,pain scores,knee function scores,clinical efficacy and complications of the two groups were compared.
Results
The operation time and hospitalization time of the observation group were shorter than those of the control group,and the differences were statistically significant (P＜0.05).The visual analogue scale (VAS) score of the observation group at 3 months after operation was lower than that of the control group,the Lysholm score and the knee joint scale score of the hospital for special surgery in the United States (HSS) were higher than those of the control group,and the differences were statistically significant(P＜0.05).There were no statistically significant differences in the excellent and good rate of treatment and the total incidence of complications of the two groups (P ＞0.05).
Conclusion
In the treatment of knee osteoarthritis,limited debridement under arthroscopy and extensive debridement under arthroscopy have the same curative effect,but limited debridement under arthroscopy has the advantages of shorter operation time,less pain and more conducive to postoperative recovery.
2021 Vol. 28 (1): 111-114 [
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38
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Application effect of knee joint closure experiment in minimally invasive treatment of knee osteoarthritis
GONG Liang-jin
Objective
To investigate the application effect of knee joint closure experiment in minimally invasive treatment of knee osteoarthritis.
Methods
A total of 100 patients with knee osteoarthritis admitted to Nanchang Hongdu Hospital of TCM from January 2015 to December 2018 were selected as the research objects and divided into the control group and the observation group according to the random number table method,with 50 cases in each group.Patients in the control group were treated with conventional minimally invasive treatment,and patients in the observation group were treated with minimally invasive knee joint closed experiment.The curative effect,the knee pain degree score,joint Lysholm score,a short form of the arthritis impact measurement scales 2 (AIMS2-SF) score,high-sensitivity C-reactive protein (hs-CRP) level before and after treatment,time for knee osteoarthritis pain to disappear and time for joint range of motion recovery were compared between the two groups.
Results
The total effect rate of the observation group was higher than that of the control group,and the difference was statistically significant (P＜0.05).There were no statistically significant differences in knee pain degree score,joint Lysholm score,AIMS2-SF score and hs-CRP level between the two groups before treatment (P＞0.05).After treatment,the Lysholm score in the observation group was higher than that in the control group,the knee joint pain score,AIMS2-SF score and hs-CRP level were lower than those in the control group,and the differences were statistically significant (P＜0.05).The time for knee osteoarthritis pain to disappear and joint range of motion recovery in the observation group were shorter than those in the control group,and the differences were statistically significant (P＜0.05).
Conclusion
Minimally invasive treatment of knee joint closed experiment for patients with knee osteoarthritis can obtain a favorable effect on alleviating pain,controlling inflammation,improving joint function,and ameliorating the quality of life of the patients.
2021 Vol. 28 (1): 115-117转121 [
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Effect of arthroscopic minimally invasive internal fixation on the rehabilitation of patients with intra-knee fracture
SUN Yue-xian；HOU Yu-tong；GAO Si-si；YU Jing
Objective
To investigate the effect of arthroscopic minimally invasive internal fixation on the rehabilitation of patients with intra-knee fracture.
Methods
A total of 78 patients with intra-knee fracture who were admitted to Mudanjiang Forestry Central Hospital from January 2018 to July 2019 were selected as the research objects and divided into the open reduction group and the minimally invasive reset group by random number table method,with 39 cases in each group.The open reduction group was treated with traditional open reduction treatment,while the minimally invasive reset group was treated with arthroscopy minimally invasive internal fixation treatment.The intraoperative blood loss,duration of operation,length of hospital stay,pain score,knee rehabilitation score,total incidence of complications and fracture healing time were compared between the two groups.
Results
The intraoperative blood loss in the minimally invasive reset group was less than that of the open reduction group,the operative time,hospital stay and fracture healing time were shorter than those of the open reduction group,visual analogue scale (VAS) score and total incidence rate of complications were lower than those of the open reduction group,the knee joint scale score of the hospital for special surgery in the United States (HSS) was higher than that of the open reduction group,and the differences were statistically significant (P＜0.05).
Conclusion
Arthroscopic minimally invasive internal fixation can effectively improve the rehabilitation effect of patients with intra-knee fracture.
2021 Vol. 28 (1): 118-121 [
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Effect of laparoscopic distal gastric cancer D2 radical surgery treating advanced gastric cancer
XIAO Yu
Objective
To explore the effect of laparoscopic distal gastric cancer D2 radical surgery treating advanced gastric cancer.
Methods
A total of 84 patients with advanced gastric cancer who underwent surgical treatment in Anshan Tumor Hospital from April 2017 to April 2019 were selected as observation objects.The clinical data of the patients were retrospectively analyzed.According to the different treatment schemes,the patients were divided into control group (traditional open gastric cancer radical surgery) and observation group (laparoscopic distal gastric cancer D2 radical surgery),with 42 cases in each group.The surgical indexes,prognosis and postoperative complications of the two groups were analyzed.
Results
The operative time of patients in the observation group was longer than that of the control group,the intraoperative blood loss was less than that of the control group,and the anal exhaust time and hospital stay were shorter than those of the control group,with statistically significant differences (P＜0.05).There was no significant difference in the number of lymph node dissection between the two groups (P＞0.05).The total incidence of postoperative complications was 16.67% in the observation group and 19.05% in the control group,and there was no statistically significant difference between the two groups (P＜0.05).
Conclusion
The curative effect of laparoscopic distal gastric cancer D2 radical surgery for advanced gastric cancer is equivalent to that of traditional open gastric cancer radical surgery.Although the operation time is longer,the intraoperative blood loss of patients is less and the safety is higher.The laparoscopic distal gastric cancer D2 radical surgery can also accelerate the recovery of patients and shorten the hospitalization time of patients,which is worthy of clinical application.
2021 Vol. 28 (1): 122-124 [
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Clinical application effect comparison of breast conserving surgery and radical mastectomy in early breast cancer
XUE Feng； JIANG Xue▲
Objective
To explore the clinical application effect of breast conserving surgery and radical surgery in early breast cancer.
Methods
A total of 100 patients with early breast cancer admitted to Dalian Central Hospital from January 2015 to May 2017 were selected as the research objects.They were divided into experimental group (50 cases)and control group (50 cases) by subsection randomization method.The control group was treated with radical mastectomy,while the experimental group was treated with breast conserving surgery.Clinical indicators,complications,disease recurrence,distant metastasis,and 3-year survival were compared between the two groups.
Results
The incision length,operation time and hospital stay of the experimental group were shorter than those of the control group,and the intraoperative blood loss was less than that of the control group,with statistically significant differences (P＜0.05).The total incidence of complications in the experimental group was 4.00%,lower than that in the control group (18.00%),and the difference was statistically significant (P＜0.05).There were no significant differences in disease recurrence rate,distant metastasis rate and 3-year survival rate between the two groups (P＞0.05).
Conclusion
Both early breast cancer patients undergoing breast conserving surgery and radical surgery can obtain good results.The application of breast conserving surgery can reduce the degree of surgical trauma of patients and control the occurrence of complications,which is of great significance.
2021 Vol. 28 (1): 125-127转131 [
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Intervention effect of Cinobufotalin Tablets on coagulation status and quality of life in patients with advanced lung cancer
ZHAO Wei
Objective
To analyze the intervention effect of Cinobufotalin Tablets on the coagulation status and quality of life in patients with advanced lung cancer.
Methods
A total of 122 patients with advanced lung cancer who were admitted to the Department of Oncology of Fushun Central Hospital from October 2018 to October 2019 were selected as the research subjects.According to the random number table method,they were divided into study group and control group,61 cases in each group.In the control group,chemotherapy treatment was used,while in the study group,patients received Cinobufotalin Tablets combined with chemotherapy.The coagulation status,quality of life rating scale(SF-36) score,pain numerical rating scale (NRS) score,and therapeutic efficacy before treatment and after 3 cycles of treatment were compared between the two groups.
Results
Before treatment,there were no significant differences in platelet (PLT),D-dimer,SF-36 score,plasma fibrinogen (FIB) and NRS between the two groups (P＞0.05).After treatment,PLT,D-dimer and FIB of the study group were lower than those of the control group,and the differences were statistically significant (P＜0.05).The treatment effect of the study group was higher than that of the control group,and the difference was statistically significant (P＜0.05).After treatment,the SF-36 score of the study group was higher than that of the control group,and the difference was statistically significant (P＜0.05).The NRS score of the study group was lower than that in the control group,and the difference was statistically significant (P＜0.05).
Conclusion
Treating patients with advanced lung cancer adding Cinobufotalin Tablets can effectively improve the coagulation status of the patients,reduce their pain,and enhance the clinical efficacy and quality of life.
2021 Vol. 28 (1): 128-131 [
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Clinical significance of neutrophil/lymphocyte ratio,serum CA125 and CA199 detection in adenomyosis and endometriosis
SU Jia-lin； ZHANG Yun； LU Chao-xia； WU Hai-gen
Objective
To investigate the clinical significance of neutrophil/lymphocyte ratio (NLR),serum CA125 and CA199 detection in adenomyosis and endometriosis.
Methods
A total of 52 patients with endometriosis and 50 patients with adenomyosis who admitted to Jiangxi Maternal and Child Health Hospital from February 2018 to October 2019 were selected as observation group 1 and 2,and 50 healthy women of childbearing age were selected as control group.NLR,serum CA125 and CA199 were detected in all three groups,and the levels of NLR,serum CA125 and CA199,positive rates of NLR,serum CA125,CA199 and combined detection among the three groups were compared.
Results
The levels of NLR,serum CA125 and CA199 in observation group 1 and 2 were higher than those in control group,and the differences were statistically significant (P＜0.05).The level of serum CA125 in observation group 2 was higher than that in observation group 1,the level of CA199 was lower than that in observation group 1,and the differences were statistically significant (P＜0.05).There were statistically significant differences in levels of NLR,serum CA125 and CA199 in different stages in the observation group 1 (P＜0.05).The positive rates of NLR,serum CA125,CA199 and combined detection in observation group 1 and 2 were higher than those in control group,and the differences were statistically significant (P＜0.05).The positive rate of combined detection in observation group 1 and 2 were higher than those in the single index detection,and the differences were statistically significant (P＜0.05).The positive rate of serum CA199 detection in observation group 1 was higher than that in observation group 2,and the difference was statistically significant (P＜0.05).
Conclusion
The combined detection of NLR,serum CA125 and CA199 in the detection of endometriosis and adenomyosis has significant application value,it can identify the pathological stages of endometriosis,and it is worthy of clinical promotion and application.
2021 Vol. 28 (1): 132-134转138 [
Abstract
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54
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135
Effect of early mother-infant skin contact on newborn breastfeeding and blood glucose
CHEN Lang； XU Juan-juan； ZHENG Xiao-wen
Objective
To explore the effect of early mother-to-child skin contact on newborn breastfeeding and blood glucose.
Methods
Eighty parturients and newborns who gave birth in the Obstetrics Department of Shenzhen Futian Maternal and Child Health Hospital from April to November 2019 were selected as the research subjects.They were divided into a control group (n=40,routine obstetric intervention) and an observation group (n=40,early skin contact) equally according to the simple randomization.The blood glucose,feeding status of the newborns,and the maternal lactation and uterine involution in the two groups were observed.
Results
After the intervention,the blood glucose level of newborns in the observation group was higher than that of the control group,and the incidence of hypoglycemia was lower than that of the control group with statistical significances (P＜0.05).In the observation group,the rate of breastfeeding within 30 minutes after giving birth and the rate of breastfeeding completion within 90 minutes,the rate of exclusive breastfeeding before discharge,and the rate of exclusive breastfeeding for three months were all higher than those of the control group,and the differences were statistically significant (P＜0.05).In the observation group,lactation starting time was shorter than that of the control group.The uterine fundus at 24 h and 48 h was lower than that at 2 h after delivery,but the height of uterine descending at 24 h and 48 h after delivery in the observation group was greater than that of the control group,and the differences were statistically significant (P＜0.05).
Conclusion
Early mother-tochild skin contact can reduce the incidence of neonatal hypoglycemia,improve breastfeeding efficiency,and promote lactation initiation and uterine recovery.
2021 Vol. 28 (1): 135-138 [
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43
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139
Influence of painless labor on induction of COOK balloon and maternal and neonatal outcomes
LI Qiao-chan
Objective
To investigate the effect of painless labor on the induction of COOK balloon and maternal and neonatal outcomes.
Methods
A total of 190 full-term primiparous women who underwent COOK balloon induction in Maternal and Child Health Family Planning Service Center in Wuchuan City,Guangdong Province from August 2017 to August 2019 were selected as the research objects and divided into the control group and the observation group according to the lottery grouping method,with 95 cases in each group.The control group was given routine delivery,and the observation group was given painless delivery.Cervical maturity,pain,pregnancy outcome,labor time,adverse maternal and neonatal outcomes were compared between the two groups.
Results
There was no significant difference in cervical maturity (Bishop) score between the two groups before and after intervention (P＞0.05).The visual analogue scale (VAS)score of the observation group after intervention was lower than that of the control group,and the difference was statistically significant (P＜0.05).The natural delivery rate in the observation group was higher than that in the control group,the cesarean delivery rate was lower than that in the control group,and the differences were statistically significant (P＜0.05).The time of the first labor of the spontaneous labor women in observation group was shorter than that of the control group,and the difference was statistically significant (P＜0.05).The total incidence of adverse maternal and neonatal outcomes in the observation group was lower than that in the control group,and the difference was statistically significant (P＜0.05).
Conclusion
Painless delivery in COOK balloon induced labor can reduce pain,increase the rate of natural delivery,shorten the labor time and improve maternal and child outcomes.
2021 Vol. 28 (1): 139-142 [
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42
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143
Application effect of Tromethamine combined with intrauterine balloon placement in postpartum hemorrhage after cesarean section of placenta previa
YUAN Qiong
Objective
To investigate the application effect of Tromethamine combined with intrauterine balloon placement in postpartum hemorrhage after cesarean section of placenta previa.
Methods
A total of 220 patients with postpartum hemorrhage after cesarean section of placenta previa who were admitted to Yichun Maternal and Child Health Hospital of Jiangxi Province from October 2015 to December 2018 were selected as the research objects and divided into the control group and the observation group by random number table method,with 110 cases in each group.The control group was treated with Oxytocin combined with intrauterine balloon placement.The observation group was treated with Tromethamine combined with intrauterine balloon placement.The hemoglobin contents,postpartum hemorrhage and adverse reactions were compared between the two groups.
Results
The hemoglobin contents in the two groups after surgery were lower than those before surgery,and the differences were statistically significant (P ＜0.05).The hemoglobin content in the observation group after surgery was higher than that in the control group,and the difference was statistically significant (P＜0.05).The blood loss in the observation group at 2 and 24 h postpartum was less than that in the control group,and the differences were statistically significant (P＜0.05).There were no statistically significant differences in the incidence rates of adverse reactions such as nausea and vomiting,transient hypertension,fever,gastrointestinal reactions between the two groups (P＞0.05).
Conclusion
Tromethamine combined with intrauterine balloon placement can reduce the amount of postpartum hemorrhage after cesarean section of placenta previa.
2021 Vol. 28 (1): 143-145转149 [
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41
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146
Effect of Budesonide,Azithromycin and Terbutaline on the treatment of children with acute bronchitis
ZHAO Na
Objective
To investigate the effect of Budesonide,Azithromycin and Terbutaline on the treatment of children with acute bronchitis.
Methods
Clinical data of 96 children with acute bronchitis treated in Tai′an Maternal and Child Health Hospital,Shandong Province from March 2018 to March 2019 were retrospectively analyzed and divided into the control group and the study group according to different treatment methods.The control group was treated with Azithromycin and Terbutaline,while the study group was treated with Budesonide on the basis of the control group.The time of symptom disappearance and hospital stay,blood gas indexes,forced expiratory volume in 1 second (FEV
1
),maximal expiratory flow at 50% of the forced vital capacity (MEF
50
) and peak expiratory flow (PEF) of the two groups were compared.
Results
The time of symptom disappearance and hospital stay in the study group were shorter than those in the control group,and the differences were statistically significant (P＜0.05).There were no statistically significant differences in the fraction of inspiration oxygen (FiO
2
),arterial partial pressure of oxygen (PaO
2
) and partial pressure of carbon dioxide in artery (PaCO
2
) between the two groups before treatment (P＞0.05).After treatment,the FiO
2
and PaCO
2
in the study group were lower than those in the control group,PaO
2
was higher than that in the control group,and the differences were statistically significant (P＜0.05).There were no statistically significant differences in FEV
1
,MEF
50
and PEF between the two groups before treatment (P＞0.05).After treatment,the FEV
1
,MEF
50
and PEF in the study group were higher than those in the control group,and the differences were statistically significant (P＜0.05).
Conclusion
For children with acute bronchitis,Budesonide,Azithromycin and Terbutaline in combination can improve lung function and blood gas indexes,shorten the time of symptom disappearance and hospital stay,and symptoms disappearing in a short period of time,which is worthy of clinical promotion and application.
2021 Vol. 28 (1): 146-149 [
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45
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150
Effect of timing of pregnancy termination on pregnancy outcome in pregnant women with early onset severe preeclampsia
WANG Chen
Objective
To investigate the effect of timing of pregnancy termination on pregnancy outcome in pregnant women with early onset severe preeclampsia.
Methods
The complete clinical data of 82 pregnant women with early onset severe preeclampsia who were admitted to the Maternal and Child Health Care Hospital of Dalian City from January to December 2019 were retrospectively analyzed.The pregnant women with early onset severe preeclampsia were divided into A group (n=40,gestational age＜32 weeks) and B group (n=42,32 weeks≤gestational age≤34 weeks) according to the different time of pregnancy termination.The general situations and pregnancy outcome were compared between the two groups.
Results
The total incidence of adverse pregnancy outcome in B group was lower than that in A group after treatment (P＜0.05).The total incidence of complications in B group was lower than that in A group (P＜0.05).
Conclusion
Pregnant women with early onset severe preeclampsia choose to terminate their pregnancy at gestational age of 32-34 weeks,it is conducive to achieving good mother-fetus outcome and decreasing the incidence of complications,which is worthy of learning.
2021 Vol. 28 (1): 150-152 [
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40
)
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153
Clinical effect of endoscopic transnasal decompression of non-photosensitive traumatic optic canal in the treatment of optic neuropathy
ZHENG Feng； WANG Ying； XU Zhong-yu； CHEN Chun
Objective
To explore the clinical effect of endoscopic transnasal optic canal decompression in the treatment of non-photosensitive traumatic optic neuropathy.
Methods
A total of 61 cases of traumatic optic neuropathy with no light perception were selected in Jieyang People′s Hospital from January 2015 to October 2019.According to different treatment plans,they were divided into observation group (32 cases) and control group (29 cases).The control group was treated with conventional drugs,while the observation group was treated with endoscopic transnasal optic canal decompression based on the control group.3 months after treatment,the clinical efficacy,postoperative complications and quality of life of patients were compared between the tow groups.
Results
The total clinical effective rate of the observation group was higher than that in the control group,the difference was statistically significant (P＜0.05).The total incidence of complications of the observation group was lower than that of the control group,the difference was statistically significant (P＜0.05).The QOL score of the observation group was higher than that of the control group,the difference was statistically significant (P＜0.05).
Conclusion
Endoscopic transnasal optic canal decompression is effective in the treatment of non-photosensitive traumatic optic neuropathy.It can improve the visual acuity of patients,reduce complications and improve their prognosis and quality of life.It is worth popularizing and studying deeply in clinical practice.
2021 Vol. 28 (1): 153-156 [
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47
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157
Clinical application of magnetic attachments in oral restoration
MA Liang
Objective
To explore the clinical application effect of magnetic attachments in oral restoration.
Methods
A total of 78 patients with dentition defect from November 2018 to December 2019 in Liaoning Health Industry Group Iron Coal General Hospital were selected as the study objects,according to the odd and even number of admission order,they were divided into control group (39 cases) and study group (39 cases).The patients in the control group were repaired by routine methods,the patients in the study group were treated with magnetic attachments to restore residual teeth,residual roots and overdentures on residual crowns.The mastication efficiency and fixation force were compared in the two groups.
Results
At the time of cementation and 1.5 months after cementation,the mastication efficiency and fixation force of patients in the study group were higher than those in the control group during the same period,and the differences were statistically significant (P＜0.05).The appearance,comfort and voice scores of patients in the study group were higher than those in the control group after cementation,and the differences were statistically significant(P＜0.05).After 3 months of follow-up,the total incidence of adverse reactions in the study group was lower than that in the control group,and the difference was statistically significant (P＜0.05).
Conclusion
The clinical effect of magnetic attachment in dentition defect patients is good,and the stability of denture is stable,which is worth popularizing.
2021 Vol. 28 (1): 157-159转162 [
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40
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160
Clinical effect of trabeculectomy combined with Mitomycin C in the treatment of glaucoma
YU Jiao
Objective
To explore the clinical effect of trabeculectomy combined with Mitomycin C in the treatment of glaucoma.
Methods
A total of 106 glaucoma patients who underwent surgical treatment in Fushun Ophthalmopathy Hospital from December 2016 to December 2018 were selected as observation objects.According to the simple randomization method,patients were divided into control group and observation group,with 53 cases in each group.Patients in the control group were treated with conventional trabeculectomy.Patients in the observation group were treated with trabeculectomy combined with Mitomycin C.The success rate of treatment,intraocular pressure level and postoperative complication rate of patients in the two groups at different time periods were observed.
Results
The success rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).The postoperative intraocular pressure in the two groups was lower than that before operation,and the difference was statistically significant (P＜0.05).There was no significant difference in IOP between the observation group and the control group before and 1 week after operation (P＞0.05).At 3 months,6 months and 12 months after operation,the intraocular pressure of the patients in the observation group was lower than that of the patients in the control group,and the difference was statistically significant (P＜0.05).There was no significant difference in the total incidence of postoperative complications between the two groups (P＞0.05).
Conclusion
Trabeculectomy combined with Mitomycin C is effective in the treatment of glaucoma.It can improve the success rate of surgery,lower the intraocular pressure of patients better,and does not increase postoperative complications.The treatment effect is safe and reliable,and has high application value.
2021 Vol. 28 (1): 160-162 [
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44
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163
Effect of Dolasetron in enhanced recovery after surgery in preventing postoperative nausea and vomiting in patients with hip replacement
ZENG Geng-hui； TU Xin-xiang； HU Qin-qing
Objective
To investigate the effect of Dolasetron in enhanced recovery after surgery (ERAS) in preventing postoperative nausea and vomiting in patients with hip replacement.
Methods
From January to December 2018,60 patients in the Second People′s Hospital of Shantou who needed artificial total hip replacement were selected as the research objects and they were divided into the study group (n=30) and the control group (n=30) by the random number table method.Both of the two groups were treated with unilateral artificial total hip replacement and had perioperative ERAS intervention,and the patients in the study group received intravenous drip of 12.5 mg Dolasetron Mesylate half an hour before skin incision to prevent postoperative nausea and vomiting.The postoperative nausea and vomiting rate and total incidence rate of complications between the two groups were compared.The visual analogue scale (VAS) was used to evaluate the pain symptoms before and after operation of the two groups,and the Harris hip joint function score was used to evaluate the recovery of hip joint function in the two groups at 3 months after the operation.
Results
The nausea and vomiting rate,total incidence rate of complications,and the VAS scores at 1 and 3 months after operation in the study group were lower than those in the control group,and the Harris hip joint function score at 3 months after operation in the study group was higher that in the control group,with statistically significant differences (P＜0.05).The VAS scores of the two groups at 1 and 3 months after operation were lower than those before operation in the same group,with statistically significant differences (P＜0.05).
Conclusion
Dolasetron has a good effect in the intervention of ERAS,which can effectively prevent nausea and vomiting and promote the recovery of joint function in patients with hip replacement,and is worthy of promotion and application.
2021 Vol. 28 (1): 163-165转169 [
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41
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166
Application effect of bilateral femoral nerve block combined with general anesthesia in double knee arthroplasty
YU Miao； SHANG Yu
Objective
To explore the application value of bilateral femoral nerve block combined with general anesthesia in double knee arthroplasty.
Methods
A total of 68 patients who were scheduled to undergo double knee arthroplasty in Central Hospital Affiliated to Shenyang Medical College from August 2018 to August 2019 were selected as the research objects.The patients were divided into the control group(n=34)and the observation group(n=34)according to the random numerical table method.The patients in the control group received general anesthesia,while the patients in the observation group received bilateral femoral nerve block combined with general anesthesia.The changes of different intraoperative periods of heart rate (HR),mean arterial pressure (MAP),narcotic drug use,consciousness recovery time,extubation time and perioperative adverse reactions in the two groups were observed.
Results
There were no significant differences in HR and MAP between the two groups before anesthesia (T
1
),immediately after tracheal intubation (T
2
),5 min after tourniquet was started (T
3
),5 min after tourniquet was stopped (T
4
) and immediately after tracheal catheter was pulled out (T
5
) (P>0.05).The levels of HR,MAP at T
2
,T
3
and T
4
of patients of the two groups were lower than those at T
1
,and the differences were statistically significant (P＜0.05).The dosages of Propofol and Remifentanil in the observation group were less than those in the control group,the recovery time of consciousness and extubation time in the observation group were shorter than those in the control group,and the visual analogue pain score (VAS) in the observation group was lower than that in the control group (P＜0.05).The usage rate of antihypertensive drugs or heart rate reducing drugs,the incidence rate of choking cough after extubation,the agitation rate during awakening period and the incision pain rate after extubation in the observation group were lower than those in the control group (P＜0.05).
Conclusion
The application of bilateral femoral nerve block combined with general anesthesia in double knee arthroplasty can maintain the stability of patients′ hemodynamics,reduce the use of intravenous analgesic drugs and opioid analgesic drugs,shorten the recovery time of patients′ consciousness and extubation time,and relieve postoperative pain,reduce the risk of complications.
2021 Vol. 28 (1): 166-169 [
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48
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170
Antispasmodic and analgesic effect of Atropine combined with Phloroglucinol before hysterosalpingography
RONG Yu-tian； LIN Liang-chu； LIN Xiao-lian
Objective
To observe the antispasmodic and analgesic effect of Atropine combined with Phloroglucinol before hysterosalpingography (HSG).
Methods
Totally 138 patients (246 fallopian tubes) with infertility who underwent HSG from November 2018 to November 2019 in Outpatient of Taishan People′s Hospital were selected as the research subjects.They were divided into three groups by the random number table method.The Atropine group (46 cases,82 fallopian tubes)was injected with Atropine intramuscularly before HSG,the Phloroglucinol group(46 cases,83 fallopian tubes)was injected with Phloroglucinol intramuscularly before HSG,and the combined group (46 cases,81 fallopian tubes)was injected with Phloroglucinol combined with Atropine intramuscularly before HSG.The HSG examination time,contrast medium dosage,pain degree,cervical softening,and fallopian tube patency of the three groups were recorded,and the total incidence of adverse reactions in the three groups was compared.
Results
The cervical softening rate of the combined group was 97.83%,higher than that of the Phloroglucinol group and the Atropine group accounting for 89.13% and 80.43%,respectively,the cervical softening rate of the Phloroglucinol group was higher than that of the Atropine group,and the differences were statistically significant (P＜0.05).The patency rate of the fallopian tubes in the combined group and the Phloroglucinol group was 75.31% and 69.88%,both higher than that in the Atropine group accounting for 60.98%,and the differences were statistically significant (P＜0.05).The score of visual analogue scale(VAS) in the combined group was lower than that in the Phloroglucinol group and the Atropine group,and the VAS score in the Phloroglucinol group was lower than that in the Atropine group,with statistical significances (P＜0.05).The total incidence of adverse reactions in the combined group and Phloroglucinol group was 19.57% and 13.04%,respectively,which was lower than 32.61% in the Atropine group,and the difference was statistically significant (P＜0.05).There were no statistically significant differences in the HSG examination time and contrast medium dosage of the three groups (P＞0.05).Conclusion The application of Atropine combined with Phloroglucinol before HSG can further soften the cervix and alleviate pain without increasing adverse reactions.It is recommended for promotion.
2021 Vol. 28 (1): 170-173 [
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53
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174
Clinical application of Ropivacaine combined with Sufentanil for continuous subarachnoid block in labor analgesia
FENG Chun-jing
Objective
To explore the application effect of continuous subarachnoid block of Ropivacaine combined with Sufentanil in labor analgesia during labor.
Methods
A total of 100 pregnant women who delivered in the Dalian Maternal and Child Health Hospital Affiliated to Dalian Medical University from January to December 2019 were selected as the research objects.According to the random number table method,they were divided into group A and group B,50 cases in each group.Group A used Ropivacaine combined with Sufentanil for continuous subarachnoid block analgesia.Group B received only Ropivacaine for continuous subarachnoid block analgesia.The duration of labor,pain score,onset time of analgesia,duration of first analgesia,and incidence of adverse reactions were compared in the two groups.
Results
There was no significant difference in the duration of the first and second stages of labor between group A and B (P＞0.05);the pain scores of parturients in group A were lower than those in group B at the 1 h of analgesia,the time of 7-8 cm in uterine opening and the time of full opening in uterine orifice,the differences were statistically significant(P＜0.05);the onset time of analgesia in group A was shorter than that in group B,but the duration of first analgesia was longer than that in group B,the differences were statistically significant (P＜0.05);there was no significant difference in the total incidence of adverse reactions between group A and group B (P＞0.05).
Conclusion
The continuous subarachnoid block of Ropivacaine combined with Sufentanil has a significant analgesic effect in the labor analgesia during labor,which is worthy of clinical promotion.
2021 Vol. 28 (1): 174-176 [
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48
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Application of intermittent breathing combined with positive end-expiratory pressure ventilation in ureteral soft mirror surgery
TANG Tao； LIN Ping
Objective
To explore the clinical application value of intermittent breathing combined with positive end-expiratory (PEEP) pressure ventilation in ureteral soft mirror surgery.
Methods
A total of 80 cases with ureter and kidney stones from November 2019 to May 2020 treated with soft-mirror lithotripsy under tracheal intubation under general anesthesia in Dalian Friendship Hospital were randomly divided into two groups,40 cases in each group.The patients in control group were given intermittent breathing,the patients in observation group were given intermittent breathing combined with low-level PEEP.Then the blood gas analysis was compared and the respiratory mechanics indexes were compared at 10 min minutes of respiratory recovery.The quality indexes of anesthesia flexible ureteroscopy surgery were compared and the respiratory complications were compared.
Results
After 10 minutes of breathing recovery,Pa-CO
2
level in the observation group was lower than that in the control group,PaO
2
level was higher than that in the control group,the differences were statistically significant (P＜0.05).The Ppeak and Pmean were lower in the observation group than those in the control group,the differences were statistically significant (P＜0.05);the time to wake up from anesthesia and the time to remove the tracheal tube in the observation group were shorter than those in the control group (P＜0.05);the total incidence of complications in the observation group during the peri-anaesthesia period was lower than that in the control group,and the difference was statistically significant (P＜0.05).
Conclusion
The application of intermittent ventilation combined with PEEP intervention in ureteral soft-mirror lithotripsy can better maintain respiratory function and promote anesthesia recovery,so it can reduce respiratory-related complications.
2021 Vol. 28 (1): 177-179 [
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43
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180
Correlation analysis of anxiety and depression symptoms and self-efficacy in patients with repeated embryo transplantation failure and nursing countermeasures
ZHANG Xin； LIU Li-ying； SUN Xiao； GUO Shuai-shuai
Objective
To study the correlation between anxiety and depression symptoms and self-efficacy in patients with repeated embryo transplantation failure,and to further explore feasible psychological nursing countermeasures.
Methods
A total of 220 patients with repeated embryo transplantation failure in the Reproductive Medicine Center of Shenyang Women′s and Children′s Hospital from January 2017 to December 2019 were selected as research objects.General information questionnaire,general self-efficacy scale and hospital anxiety and depression scale were used to investigate.
Results
Among 220 patients with repeated embryo transplantation failure,according to the criteria of hospital anxiety and depression form,all the patients were divided into the anxiety group (115 cases) and the non-anxiety group (105 cases),the depression group (148 cases) and the non-depression group (72 cases),the anxiety with depression group (95 cases) and the non-complication group (125 cases).The self-efficacy score of the anxiety group was lower than that of the non-anxiety group,the self-efficacy score of the depression group was lower than that of the nondepression group,and the self-efficacy score of the anxiety with depression group was lower than that of the non-complication group,all the differences were statistically significant (P＜0.05).Both anxiety and depressive symptoms were negatively correlated with self-efficacy (r=-0.172,-0.233,P＜0.05).
Conclusion
Nurses should take positive and correct nursing countermeasures to relieve or eliminate anxiety and depression of patients with repeated embryo transplantation failure,to improve their sense of self-efficacy,and to improve their psychological health.
2021 Vol. 28 (1): 180-183 [
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60
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184
Psychological health survey and intervention strategies of HBV and HCV single-reagent nucleic acid reactive unpaid blood donors
XIAO Hui-fen； YANG Zhuan-xiao； FANG Ying； LI Yun-yun
Objective
To investigate the effect of hepatitis B virus (HBV) and hepatitis C virus (HCV) single-reagent nucleic acid and enzyme-linked immunoassay reactivity results on the psychological behavior status of unpaid blood donors,and explore the necessity of implementing reasonable psychological interventions to increase public trust in unpaid blood donation and avoid blood donor loss.
Methods
Blood donors whose HBV and HCV enzyme-linked immunoassays and nucleic acid tests were blocked in Longgang Blood Station of Shenzhen City from 2015 to 2018 were selected,and 137 among of them who agreed to conduct telephone interviews and self-made questionnaires were selected as the evaluation objects.Psychological survey was conducted in the form of interview with the self-rating symptom scale(SCL-90) and self-made questionnaire to evaluate the psychological impact of single item blood test screening results on 92 blood donors who agreed to follow-up visits and explore the necessity and intervention strategies of implementing rational psychological intervention measures.
Results
A total of 137 unpaid blood donors received a preliminary psychological evaluation during the telephone return visit after blood donation.Most of them had a strong demand for answering questions on professional hotline,publicity brochures for families with relevant knowledge and expecting blood stations to conduct reexamination.Among the 92 blood donors who agreed to conduct the SCL-90 survey,except for the positive symptoms,the scores of depression,hostility,and psychosis at the first evaluation were all lower than those of the national norm,and the scores of physical symptoms,compulsions,interpersonal sensitivity,anxiety,and paranoia were all higher than those of the national norm,the differences were statistically significant (P＜0.05).After psychological intervention,the blood donors′ interpersonal sensitivity,anxiety,and hostility scores were lower than those at the first evaluation,and the differences were statistically significant (P＜0.05).
Conclusion
The implementation of appropriate psychological interventions has a positive effect on alleviating the negative psychology of blood donors.Serological enzyme-linked immunoassay combined with nucleic acid testing provides a basic guarantee for the safety of clinical blood transfusion,but single-reactivity blocked blood donors should be given corresponding re-inspection and return guidance.Paying attention to the psychological demands of blood donors is of great significance for protecting the blood source and enhancing the public′s awareness and enthusiasm for unpaid blood donation.
2021 Vol. 28 (1): 184-187 [
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37
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188
Status and analysis of structured nursing diagnosis terminology in PIO nursing records
MENG Xiang-hong； GU Jian-fang； YU Xiao-juan； ZOU Li-wen； HUANG Yan-hong； BI Ting-ting； QIU Hong
Objective
To discover the status of structured nursing diagnosis in the PIO nursing records of inpatients.
Methods
In this study,objective sampling method was used.In June 2017,131 inpatients discharged from 22 specialties in 2 secondary and tertiary comprehensive medical institutions in Shanghai were collected.Nursing information team members extracted and counted the nursing diagnosis and frequency in nursing records,and compared with the principles of nursing diagnosis terms in International Classification of Nursing Practice (ICNP).
Results
A total of 121 nursing diagnosis were extracted,of which frequency ranging from 1 to 73.Total frequency was 897 times and 81(66.94%) of them met the principle of composition in ICNP.
Conclusion
Nursing diagnosis structure is a part of nursing terminology standardization,which is directly related to the collection of nursing indicators and the sharing of information.Nursing managers should pay more attention to the construction of nursing informatization in medical institutions.
2021 Vol. 28 (1): 188-190转194 [
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35
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191
Analysis and recruitment strategy of apheresis platelets donors in Jining region
ZHANG Hong
Objective
To analyze the population structure of apheresis platelets voluntary blood donors from 2013 to 2017 in Jining Central Blood Station,to formulate recruitment strategies suitable for the Jining region,and to better retain blood donors and ensure blood supply safety.
Methods
Using the information of blood donors in the database of blood information management system,the population structure of 26 977 people who volunteered to donate apheresis platelets in Jining Central Blood Station from 2013 to 2017 was analyzed.
Results
The number of apheresis platelets donors and the amount of therapeutic doses were increasing annually.According to gender statistics,22 694 cases(84.12%) were male,and 4238 cases (15.88%) were female,the majority of the blood donors were male,the average gender ratio was 5.30∶1.The most in the 35 to ＜45 years old group accounted for (40.74%) (10 991 cases),the 45 to ＜56 years old group accounted for (32.28%) (8708 cases).The blood donors with junior middle school education were the most (9100 cases,33.69%),followed by high school education (6875 cases,25.48%).The blood donors were more in the group of workers (11 530 cases,42.74%) and independent profession (7406 cases,27.45%).The number of apheresis platelets donors who donated 1 to 3 times a year accounted for 52.29% (2688/5140).
Conclusion
According to the distribution characteristics of apheresis platelets in Jining area,it is necessary to strengthen publicity for female blood donors,highly educated personnel and national public officials with low blood donation,and formulate different recruitment strategies and service processes according to different groups,so as to ensure clinical use the safety and sufficiency of apheresis platelets and the establishment of long-term mechanism.
2021 Vol. 28 (1): 191-194 [
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Investigation and analysis of influence of isolation mode on psychological health of 2019-nCoV pneumonia residents′ during epidemic prevention
HUANG Cui-yi； CHEN Jun-yong；FENG Hui-yan； CHEN Wen-rong；CHEN Shang-li； SHAN Yan-chun； TANG Zhi
Objective
To understand 2019-nCoV pneumonia in different isolation methods of residents′ mental health.
Methods
From 8 to 14 on February 2020,the community residents who were isolated in three different locations,hospital isolation,hotel isolation and home isolation due to 2019-nCoV pneumonia in Shunde District,Foshan City,Guangdong Province were investigated by symptom checklist 90 (SCL-90),self-rating depression scale (SDS) and self-rating anxiety scale (SAS) respectively.
Results
SCL-90 score showed that the scores of physical,interpersonal,depression,anxiety,hostility,terror and other factors of residents in hospital isolation and hotel centralized isolation were higher than those of residents in home isolation and national adult norm (P＜0.05).The scores of depression and anxiety of residents in hospital isolation were higher than those of residents in hotel centralized isolation (P＜0.05).The scores of anxiety of residents in home isolation were higher than those of residents in national adult norm (P＜0.05).There was no significant difference in the score of SDS between isolated residents in hospitals and those of centralized isolation in hotels (P＞0.05),but which were higher than those of isolated residents at home and national adult norm (P＜0.05).There were significant differences in the scores of SAS between isolated residents in hospitals and those of centralized isolation in hotels (P＜0.05),and the scores of SAS of centralized isolation in hotels were also higher than those of isolated residents at home and national adult norm (P＜0.05).
Conclusion
When dealing the outbreak of the 2019-nCoV pneumonia,the influence of home segregation on residents′ mental health is relatively minimal.Psychological isolation should be strengthened for hospitals and hotel segregated people,and psychological pressure and related problems caused by centralized isolation measures should be reduced.
2021 Vol. 28 (1): 195-197 [
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Relationship analysis among work-family conflict,depression and job burnout in autism practitioners in Guangdong Province
DAI Shi-xia； ZHOU Xu； CHEN Yang-xia
Objective
To explore the relationship among work-family conflict,depression and job burnout in autism practitioners.
Methods
From July to October in 2019,194 autism practitioners in Shenzhen,Huizhou,Heyuan and other areas of Guangdong Province were investigated by convenience sampling method.The self-rating depression scale,job burnout scale and work-family conflict scale were used during survey.Correlation analysis,linear regression analysis and mediation analysis were used to determine the mediating role of depression in work-family conflict and job burnout in practitioners with autism.
Results
In the correlation analysis,work-family conflict was positively correlated with emotional exhaustion and cynicism in job burnout (r=0.530,0.533,P＜0.01).Depression was positively correlated with emotional exhaustion and cynicism in job burnout (r=0.484,0.368,P＜0.01).In linear regression analysis,workfamily conflict and depression positively predicted the emotional exhaustion of job burnout (P＜0.001).Work-family conflict and depression positively predicted the cynicism of job burnout (P＜0.001,P=0.002),depression positively predicted the low sense of accomplishment of job burnout (P=0.001).In mediation analysis of the relationship between work-family conflict and (burnout) emotional exhaustion,depression played a mediating role.In the relationship between work-family conflict and (job burnout) cynicism,depression also played a mediating role.
Conclusion
The depression of autism practitioners is correlated with work-family conflict and job burnout.Management departments can improve the depression of autism practitioners to reduce family-work conflicts and job burnout,and fundamentally enhance the rehabilitation effect in autistic patients.
2021 Vol. 28 (1): 198-201 [
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202
Application effect of self-examination mode of hidden danger in perioperative nursing risk management
WANG Chun-xia； DENG Shu-hong
Objective
To explore the application effect of self-examination mode of safety hidden danger in perioperative nursing risk management.
Methods
A retrospective analysis of 168 cases of surgical treatment in the Fourth Affiliated Hospital of Nanchang University from January 2014 to December 2015 was made.A total of 84 patients who received surgical treatment from January to December 2014 were set as the control group,and 84 patients who received surgical treatment from January to December 2015 were set as the observation group.The incidence of nursing risk events,total hursing satisfaction,perioperative health education awareness rate and nursing staff safety awareness were compared between the two group.
Results
The incidence of nursing risk events in the observation group was 1.19%,lower than 9.52% of the control group,the total nursing satisfaction rate was 96.43%,the awareness rate of perioperative health education was 95.23%,which were higher than 88.10% and 85.71% of the control group,the differences were statistically significant (P＜0.05);the awareness score of safety hazards of nursing staff in the observation group was (25.33±1.52) points,safety hazard management attitude score was（26.51±1.57）points，risk awareness score was（7.98±0.32）points，intention of safety hazard management score was（8.16±0.20）points，positive attitude of nursing work score was（18.30±0.18）points，which were higher than those in control group of (20.54±2.17),(21.74±2.28),(6.56±0.78),(7.42±0.39) and (15.52±1.61) points,with statistical differences (P＜0.05).
Conclusion
The self-examination mode of safety risks can reduce the incidence of perioperative nursing risk events,improve patient′ medical experience,improve nursing satisfaction,and improve the level of patients′ health knowledge,enhance the awareness of safety risks of nursing staff,which is worthy of application.
2021 Vol. 28 (1): 202-204转208 [
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42
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Application of high quality nursing intervention in endoscopic variceal ligation for patients with esophageal and gastric varices during perioperative period
CHEN Bei； RAO Dan-xia ；LI Pei-pei
Objective To investigate the application of high quality nursing intervention in endoscopic variceal ligation for patients with esophageal and gastric varices during perioperative period.Methods A total of 88 patients with esophageal and gastric varices who were admitted to Fuzhou First People′s Hospital,Jiangxi Province from January 2018 to December 2019 were selected as subjects and divided into two groups according to random number table method,44 cases in each group.Two groups underwent endoscopic variceal ligation,control group was given routine nursing,and observation group was given high quality nursing intervention based on the control group,with 2 weeks of intervention in two groups.The psychological status,quality of life and nursing satisfaction in two groups were observed.Results After intervention for 2 weeks,the scores of self-rating anxiety scale (SAS) and self-rating depression scale (SDS) in two groups were lower than those before intervention,and the SAS and SDS scores in observation group were lower than those in control group,the differences were statistically significant (P＜0.05).The scores of social function,physical function,mental function and material life status in two groups were higher than those before intervention,and the scores of observation group were higher than those of control group,the differences were statistically significant (P＜0.05).The total nursing satisfaction of observation group was higher than that of control group,the difference was statistically significant (P＜0.05).Conclusion High quality nursing intervention for esophageal and gastric varices patients with endoscopic variceal ligation during perioperative period can improve psychological status,increase quality of life and nursing satisfaction,which is worthy of clinical promotion.
2021 Vol. 28 (1): 205-208 [
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Effect of high-quality nursing on the treatment attitude,stigma and overall well-being of schizophrenic patients
JIANG Jian-mao；CHEN Ze-qun； CHEN Ze-ying； WU Guang-bing
Objective
To explore the effect of high-quality nursing on the treatment attitude,stigma and overall wellbeing of schizophrenic patients.
Methods
A total of 120 patients with schizophrenia who were hospitalized in Guangzhou Civil Affairs Bureau Psychiatric Hospital from May 2017 to November 2019 were selected as subjects.By the random number table method,they were divided into the control group and the observation group,60 cases in each group.The control group was given psychiatric routine care,and the observation group implemented quality care.The self-perception and treatment attitude questionnaire (ITAQ),the mental disorder assessment scale (ISMI) and the global well-being scale (GWB) were used to evaluate the two groups.
Results
Before intervention,the ITAQ,GWB and ISMI scores of the two groups were compared,the differences were not statistically significant (P＞0.05);the ITAQ,GWB scores of the observation group after intervention were higher than those of the control group,ISMI score was lower than that of the control group,the differences were statistically significant (P＜0.05).
Conclusion
High-quality nursing can effectively improve the patients′ treatment attitude and overall well-being,reduce the stigma,and has good clinical application value.
2021 Vol. 28 (1): 209-211 [
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Influence of fast track surgery combined with postoperative predictive nursing on the prognosis condition of patients undergoing percutaneous nephrolithotomy
CHEN Man-gui；YAN Xiao-yun； WANG Hui-fen；ZHAO Huan；DAI Chang-jun
Objective
To explore the influence of fast track surgery (FTS) combined with postoperative predictive nursing on the prognosis condition of patients undergoing percutaneous nephrolithotomy.
Methods
A total of 80 patients who received percutaneous nephrolithotomy in People′s Hospital of Linchuan District of Fuzhou City,Jiangxi Province from October 2018 to October 2019 were selected as the study objects,and they were divided into the observation group (n=40) and the control group (n=40) according to the random number table method.The patients in the control group received routine nursing during the perioperative period,while the patients in the observation group received routine nursing during the perioperative period,providing them with FTS combined with postoperative predictive nursing.The first postoperative exhaust time,hospital stay,postoperative complications (including bleeding,infection,urinary extravasation,pneumothorax，pleural effusion and ascites) and total nursing satisfaction of the two groups were observed and compared.
Results
The first postoperative exhaust time and hospital stay of patients in the observation group were shorter than those in the control group,there were significant differences (P＜0.05).The total incidence of postoperative complications in the observation group was 7.50%,which was lower than 30.00% of patients in the control group,there was significant difference (P＜0.05).The total satisfaction degree of patients in the observation group was 97.50%，which was higher than 75.00% of patients in the control group,there was significant difference (P＜0.05).
Conclusion
FTS combined with postoperative predictive nursing can significantly improve the prognosis of patients undergoing percutaneous nephrolithotomy,which can shorten the length of stay,reduce the incidence of complications,and improve the satisfaction of nursing.
2021 Vol. 28 (1): 212-215 [
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Application of perioperative psychological nursing in excimer femtosecond laser surgery for myopia
YANG Yi
Objective
To explore the effect of perioperative psychological nursing on excimer femtosecond laser surgery for myopia.
Methods
A total of 81 patients with myopic admitted to Dalian Third People′s Hospital from April 2016 to May 2018 were selected as research subjects.They were divided into control group (n=40) and observation group (n=41) by grasping balls.Patients in the control group received routine perioperative nursing,and in the observation group,psychological nursing was added on the basis of the control group.The scores of self-rating anxiety scale (SAS),selfrating depression scale (SDS) and Connor-Davidson resilience scale (CD-RISC),compliance rate with medical treatment,diopter,uncorrected visual acuity were compared between the two groups.
Results
After nursing,the SAS and SDS scores in the observation group were lower than those of the control group,while the CD-RISC score was higher than that of the control group,the differences were statistically significant (P＜0.05).The total compliance rate in the observation group was 97.6%,higher than that of the control group,accounting for 80.0%,the difference was statistically significant (P＜0.05).The diopter and uncorrected visual acuity between the two groups had no significant differences(P＞0.05).
Conclusion
Perioperative psychological nursing has a significant effect on treating myopia using excimer femtosecond laser surgery.It can reduce patients′ negative emotions and increase their medical treatment compliance,which is worthy of promotion.
2021 Vol. 28 (1): 216-218转222 [
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Application effect of health education in nursing of elderly osteoporotic hip fracture
SUN Gui-fang； DING Ying-ying； RONG Feng-ju ；GAO Xue； LI Dong-yang
Objective
To explore the application effect of health education in nursing of osteoporotic hip fracture in the elderly.
Methods
Sixty-six elderly osteoporotic hip fracture patients admitted to Hongqi Hospital Affiliated to Mudanjiang Medical University from September 2017 to September 2019 were selected as the research objects,and were divided into the control group and the observation group according to the ″dynamic random grouping method″,33 cases in each group.The control group adopted routine nursing intervention,and the observation group adopted health education.The drug knowledge mastery score,fracture incentive and prevention score,quality of life scale (SF-36) score and total nursing satistaction were compared between the two groups.
Results
After nursing,the observation group′s knowledge of osteoporosis drugs scored (74.52±4.61) points,and the score of fracture causes and preventive measures knowledge was (77.86±4.35) points,which were higher than those of the control group of (68.14±3.76) and (71.14±3.87)points (P＜0.05).The observation group′s physiological function score was (31.21±2.24) points,physiological function score was (32.86±2.64) points,vitality score was (31.97±2.74) points,social function score was (31.12±2.14) points,the role function score was (32.21±2.53) points，the cognitive function score was（31.58±1.98）points,the mental health score was (32.66±2.05),and the overall quality of life score was (34.27± 2.32) points,all higher than those of the control group of (28.12±1.35),(29.10±2.31),(28.10±1.33),(28.86±1.62),(29.11±1.10),(27.67±1.22),(28.87±1.55),(31.33±1.99) points (P＜0.05).The nursing total satisfaction of patients in the observation group was 93.94%,which was higher than 66.67% in the control group,the differences were statistically significant (P＜0.05).
Conclusion
The clinical effect of health education in nursing care of elderly osteoporotic hip fractures is significant.It can not only improve patients′health knowledge,but also improve patients′ quality of life and nursing satisfaction.It is suitable for clinical implementation and promotion.
2021 Vol. 28 (1): 219-222 [
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Application of six-handed nursing technology in autologous tooth transplantation
XIAO Qiu-yan； ZHANG Yin-yan
Objective
To explore the application of six-hand operation in autologous tooth transplantation.
Methods
A total of 84 patients undergoing autologous tooth transplantation treated in Stomatological Hospital Affiliated to Fujian Medical University from June 2018 to June 2019 were selected as the research subjects.They were divided into the control group and the experimental group according to the method of random number table,42 cases in each group.The control group was given four-hand technique for autologous tooth transplantation,and the experimental group was given six-hand technique for autologous tooth transplantation.The recovery of chewing function,occlusal function and the occurrence of adverse reactions were compared between the two groups.
Results
In the experimental group,90.48% had higher chance of returning to normal after receiving autologous tooth transplantation than that in the control group(73.81%),the difference was statistically significant (P＜0.05).The total incidence of adverse reactions in the experimental group (0.00%) was lower than that in the control group (14.29%),and the difference was statistically significant(P＜0.05).The total satisfaction of the experimental group was higher than that in the control group,the difference was statistically significant (P＜0.05).
Conclusion
Six-handed nursing for patients with autologous tooth transplantation can effectively reduce the incidence of adverse reactions such.It has a better effect.
2021 Vol. 28 (1): 223-225 [
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Application of high-quality nursing in children with pneumonia
ZHANG Shi-dai
Objective
To explore the application of high-quality nursing in children with pneumonia.
Methods
A total of 92 cases of pediatric pneumonia patients admitted to Shenyang Children′s Hospital from September 2017 to July 2019 were selected as the research objects,and they were divided into reference group (46 cases) and high-quality nursing group (46 cases) according to odd-even grouping.After the implementation of different care models,the effect was compared.
Results
The time of disappearance of cough,the time of disappearance of lung rale,the time of normal body temperature and the length of hospital stay in the high-quality nursing group were shorter than those in the reference group,the differences were statistically significant (P＜0.05).The total incidence of complications in the highquality nursing group was lower than that in the reference group (P＜0.05).After nursing,the first-second forced expiratory volume and forced vital capacity of the high-quality nursing group were higher than those of the reference group,and the differences were statistically significant (P＜0.05).
Conclusion
Compared with the conventional nursing model,high-quality nursing has obvious clinical advantages in pediatric pneumonia nursing,which can shorten the disappearance time of various symptoms,reduce the incidence of complications,and effectively improve the lung function of patients.It is recommended to promote the application.
2021 Vol. 28 (1): 226-228 [
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Effect of traditional Chinese medicine empathy nursing combined with video education nursing model on functional recovery and overall health of patients with rheumatoid arthritis in stable stage
LIU Xin
Objective
To evaluate the effect of combination of traditional Chinese medicine (TCM) empathy nursing and video health education on functional recovery and rehabilitation of patients with rheumatoid arthritis (RA) in stable stage.
Methods
A total of 90 patients with RA in stable stage who were treated in Panjin Liaohe Oilfield Gem Flower Hospital from December 2017 to December 2019 were selected and divided into two groups,45 cases in each group.The control group received routine nursing,the observation group added the TCM empathy intervention and video health education and nursing,the improvement of patients′ psychological state,self-efficacy,self-management ability and joint function were compared between the two groups.
Results
The scores of self-rating depression scale (SDS),selfrating anxiety scale (SAS)in the observation group were lower than those in the control group,and general self-efficacy scale-Schwarzer (GSES)was higher than that in the control group (P＜0.05).After intervention,the score of rating scale of health self-management skill for adults (AHSMRS) in the observation group was higher than that in the control group,the total effective rate of rehabilitation was 93.33%,higher than that in the control group (77.78%),the differences were statistically significant (P＜0.05).The joint function of the observation group was better than that of the control group after intervention,the difference was statistically significant (P＜0.05).
Conclusion
During the treatment of patients with stable RA,TCM empathy nursing and video health education intervention should be strengthened,which can effectively improve the patients′ negative emotion,improve their self-efficacy and self-management ability,promote the improvement of the overall rehabilitation effect of disease,and help patients to get more ideal improvement of joint function.
2021 Vol. 28 (1): 229-232 [
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Application effect of stepwise speech rehabilitation nursing intervention in speech disorder patients with Parkinson′s disease
ZHAO Xue
Objective
To explore the application effect of stepwise speech rehabilitation nursing intervention in speech disorder patients with Parkinson′s disease (PD).
Methods
A total of 84 patients with speech disorder of PD admitted to Shenyang Fifth People′s Hospital,Liaoning Province from July 2016 to July 2019 were selected.According to the admission sequence,they were divided into control group and observation group,42 cases in each group.Routine nursing was used in the control group,stepwise speech rehabilitation nursing intervention was used in the observation group.The noise disturbance index before and after nursing,speech expression ability and satisfaction were compared between the two groups.
Results
There was no statistically significant difference in the score of voice disorder index before nursing between the two groups (P＞0.05).The score of noise disorder index after nursing in the observation group was lower than that in the control group,the difference was statistically significant (P＜0.05).Speech expression ability and total satisfaction in the observation group were higher than those in the control group,and the differences were statistically significant (P＜0.05).
Conclusion
It is of high value to provide stepwise speech rehabilitation nursing intervention for speech disorder patients with PD.
2021 Vol. 28 (1): 233-235 [
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Preventive effect of predictive nursing on adverse events of scalp vein infusion in children
WANG Chun-li
Objective
To explore the preventive effect of predictive nursing on adverse events of scalp vein infusion in children.
Methods
From July 2018 to August 2019，102 children with scalp vein infusion treated in the Second Affiliated Hospital of Dalian Medical University were selected and divided into observation group (51 cases) and control group (51 cases) by drawing lots.The control group was given routine care,and the observation group was given predictive care.After the intervention,the incidence of adverse events of infusion and the nursing satisfaction of the family members of the two groups were compared.
Results
The total incidence of infusion adverse events in the observation group (5.88%) was lower than that in the control group (21.57%),the difference was statistically significant (P＜0.05);after the intervention,the total satisfaction rate of nursing in the observation group (96.08%) was higher than that in the control group (82.35%),the difference was statistically significant (P＜0.05).
Conclusion
The intervention of predictive nursing measures for children with scalp vein transfusion can effectively reduce the incidence of adverse events during the infusion process,improve the nursing satisfaction of the children′s family members,and is worthy of clinical promotion and application.
2021 Vol. 28 (1): 236-238 [
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Application of detailed high-quality nursing in patients with acute cerebral infarction
XU Hui-min； ZHAO Yi-shuang
Objective
To explore the clinical application value of detailed high-quality nursing in patients with acute cerebral infarction (ACI).
Methods
A total of 80 cases of ACI in Jinpu District,the First Affiliated Hospital of Dalian Medical University from June 2019 to April 2020 were selected as subjects and divided into two groups according to the random number table method,40 cases in each group.The control group received routine nursing care,the observation group received detailed high-quality nursing care,all were followed up for 1 month.The neurological function and life quality were compared;the language proficiency test in the two groups was compared;proportion of bad living habits still existing in the two groups after intervention was compared;the treatment compliance in the two groups was counted.
Results
After 1 month,the neurological European stroke score in the observation group was higher than that in the control group,the Barthel index score of improved life quality in the observation group was higher than that in the control group (P＜0.05).The language ability score in the observation group was higher than that in the control group (P＜0.05).The total proportion of smoking,drinking,greasy and spicy diet and staying up late in the observation group was lower than that in the control group (P＜0.05).The total compliance of the observation group was higher than that in the control group,the difference were statistically significant (P＜0.05).
Conclusion
Detailed high-quality nursing for patients with ACI can effectively promote the improvement of neurological function and life quality,so it can promote the recovery of language function after the onset,change bad living habits and improve treatment compliance.
2021 Vol. 28 (1): 239-241 [
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