|
|
Clinical significance of neutrophil/lymphocyte ratio,serum CA125 and CA199 detection in adenomyosis and endometriosis |
SU Jia-lin ZHANG Yun LU Chao-xia WU Hai-gen▲ |
Department of Gynecology and Obstetrics,Jiangxi Maternal and Child Health Hospital,Jiangxi Province,Nanchang 330000,China |
|
|
Abstract Objective To investigate the clinical significance of neutrophil/lymphocyte ratio (NLR),serum CA125 and CA199 detection in adenomyosis and endometriosis.Methods A total of 52 patients with endometriosis and 50 patients with adenomyosis who admitted to Jiangxi Maternal and Child Health Hospital from February 2018 to October 2019 were selected as observation group 1 and 2,and 50 healthy women of childbearing age were selected as control group.NLR,serum CA125 and CA199 were detected in all three groups,and the levels of NLR,serum CA125 and CA199,positive rates of NLR,serum CA125,CA199 and combined detection among the three groups were compared.Results The levels of NLR,serum CA125 and CA199 in observation group 1 and 2 were higher than those in control group,and the differences were statistically significant (P<0.05).The level of serum CA125 in observation group 2 was higher than that in observation group 1,the level of CA199 was lower than that in observation group 1,and the differences were statistically significant (P<0.05).There were statistically significant differences in levels of NLR,serum CA125 and CA199 in different stages in the observation group 1 (P<0.05).The positive rates of NLR,serum CA125,CA199 and combined detection in observation group 1 and 2 were higher than those in control group,and the differences were statistically significant (P<0.05).The positive rate of combined detection in observation group 1 and 2 were higher than those in the single index detection,and the differences were statistically significant (P<0.05).The positive rate of serum CA199 detection in observation group 1 was higher than that in observation group 2,and the difference was statistically significant (P<0.05).Conclusion The combined detection of NLR,serum CA125 and CA199 in the detection of endometriosis and adenomyosis has significant application value,it can identify the pathological stages of endometriosis,and it is worthy of clinical promotion and application.
|
|
|
|
|
[1] |
徐晗.子宫肌瘤手术治疗前后血清CA125 VEGF-C 及性激素水平变化及其与预后的关系[J].河北医学,2019,25(12):1972-1975.
|
[2] |
侯英,张蒙,耿宇宁.血清CA125、CA199 联合脂联素对子宫内膜癌的诊断价值[J].实用癌症杂志,2019,34(11):1760-1763.
|
[3] |
喻茂文,鄢骑兵,陈建军,等.血清CA125、CA19-9、CA724、SCCAg 联合检测在子宫内膜癌中的诊断价值[J].癌症进展,2019,17(17):2074-2078,2104.
|
[4] |
许文丽,邢秀月,徐川微.血清miR-155 水平联合HE4、CA125 对子宫内膜癌的诊断价值[J].热带医学杂志,2019,19(9):1142-1145.
|
[5] |
孟萍.血清CA125 及HE4 诊断子宫腺肌症和子宫肌瘤的临床价值[J].实用妇科内分泌电子杂志,2019,6(23):131-138.
|
[6] |
洪莲,陈旭.超声引导下射频消融治疗子宫腺肌症疗效及对血清CA125 的影响[J].现代中西医结合杂志,2019,28(23):2566-2569.
|
[7] |
杜洪钦,张慧.经阴道超声联合血清CA125 在子宫腺肌瘤中的诊断价值[J].中国保健营养,2019,29(23):297-298.
|
[8] |
杨亚锋,唐鑫强,常萌.阴道超声检查结合血清CA125 检测对子宫肌瘤与子宫腺肌病的诊断价值[J].临床医学研究与实践,2019,4(21):133-134,148.
|
[9] |
兰新志.血清HE4、CA125 和血浆D-二聚体在子宫内膜癌的表达及联合检测的临床价值[J].实验与检验医学,2019,37(5):916-918.
|
[10] |
刘家利,谢小军.子宫内膜癌组织HIF-1α、血清CA125水平在患者病情与疾病预后评估中的价值[J].陕西医学杂志,2019,48(6):800-802.
|
[11] |
霍刚,王艳.NLR、血清CA125及CA199检测在子宫腺肌病和子宫内膜异位症中的临床意义[J].临床医学研究与实践,2019,4(15):91-93.
|
[12] |
吴亚男,李红霞,霍志平,等.不同R-AFS 分期子宫内膜异位症患者血清CA125 及BDNF 检测及其诊断价值[J].临床和实验医学杂志,2019,18(10):1077-1079.
|
[13] |
刘秀玲,贺全勤.血清HE4、CA125、SCC-Ag 联合检测对诊断子宫内膜癌的临床价值[J].实用癌症杂志,2019,34(4):675-677.
|
[14] |
黄益辉,李萍.曼月乐节育环对治疗子宫腺肌症患者月经过多的疗效及对血清CA125 的影响分析[J].首都食品与医药,2019,26(11):10-11.
|
[15] |
王娜娜.TVCDS 联合血清CA125、CA199 水平检测在早期子宫内膜癌诊断中的应用价值[J].河南医学研究,2018,27(24):4534-4535.
|
[16] |
方淑芬,万玉珍.不同种类CA125 浓度测量值对子宫内膜异位症与子宫腺肌症的鉴别诊断价值[J].中国现代医生,2018,56(21):59-63.
|
|
|
|