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Quick Search     Adv Search 2020 Vol. 27, No. 14 Published: 2020-05-18   4 Value of microbiological rapid on-site evaluation in the diagnosis of pulmonary infection under bronchoscope FANG Yu-kun； LI Yu； WANG Jian； CHEN Jin-yao； SONG Jia； SHEN Qing； WU Li-jun； CHEN Qing-yong Objective To explore the value of microbiology rapid on-site evaluation (M-Rose) in the diagnosis of pulmonary infection under bronchoscope.Methods A retrospective analysis was made on 104 patients with bronchoscopic pulmonary infection in the 903th Hospital of PLA in Zhejiang Province from January to August 2018.The secretions of each patient under bronchoscope were evaluated on the spot by microbiology,and the samples were sent to the laboratory for testing at the same time,taking the report of the laboratory as the gold standard.The results of M-Rose and laboratory report are compared.Results Among the 104 cases,92 cases had definite etiology,12 cases had no definite etiology,including 55 cases of Gram-positive bacteria,17 cases of Gram-negative bacteria,3 cases of tuberculosis,4 cases of fungi,and 14 cases of mixed infection (including one case of fungus combined with bacterial infection of unknown etiology).A total of 94 cases of M-Rose had definite etiology,there were 10 cases with no definite etiology,including 56 cases of Gram-positive bacteria,17 cases of Gram-negative bacteria,3 cases of tuberculosis,5 cases of fungi,and 15 cases of mixed infection (including one case of tuberculosis with bacterial infection of unknown etiology,one case of fungus with bacterial infection without definite pathogen).There was no significant difference in the diagnosis rate between the two detection methods (P＞0.05).With the test results as the gold standard,the sensitivity and specificity of M-Rose were 100.00% and 90.91% respectively.The tuberculosis diagnostic accuracy of MRose was 100.00%,the fungus sensitivity of M-Rose was 80.00%,the specificity was 100.00%,and the overall diagnostic accuracy was 98.91%.The results of M-Rose in the diagnosis of pulmonary infection were in good agreement with the results of etiology in the laboratory (Kappa=0.907,P＜0.001).Conclusion M-Rose has a high diagnostic value for patients with pulmonary infection under bronchoscopy,which is helpful for the preliminary evaluation of the etiology of the patients with pulmonary infection,and can provide early treatment basis for the future clinical treatment. 2020 Vol. 27 (14): 4-7转29 [Abstract] ( 94 ) HTML (42 KB)  PDF  (0 KB)  ( 2 ) 8 Establishment of area of limited sampling strategies for the estimation of Mycophenolic acid area under the concentration-time curve in pemphigus patients GUO Sheng-hong ； HE Wen-li Objectives To investigate the establishment of area of limited sampling strategies for the estimation of Mycophenolic acid area under the concentration-time curve (AUC) in pemphigus patients.Methods The peripheral venous blood of 28 patients with pemphigus admitted into our hospital from October 2016 to December 2018 were collected before taking MMF and after taking MMF at 0.5,1,2,4,6,8 and 12 h.The concentration of mycophenolic acid (MPA) in plasma was measured by enzyme amplification immunoassay (EMIT).The MPA-AUC was calculated by linear trapezoid method at 0-12 h after administration.The regression equation and correlation coefficient of MPA-AUC 0-12h were estimated by SPSS software,and the accuracy of the model was evaluated by prediction error.Results A total of 28 patients with pemphigus had the same shape of MPA blood concentration time curve.Among them,the complex correlation coefficient of 1 point and 2 point fitting was lower,and the complex correlation coefficient of 3-5 point fitting was higher.A total of 9 models with high complex correlation coefficient were selected,among which the accuracy of model 3 to model 9 was increased.Conclusion Considering the operability and cost of detection,it is recommended that the mathematical model of 3 and 4 points can be used to estimate the MPA-AUC 0-12h after taking MMF in pemphigus patients. 2020 Vol. 27 (14): 8-14 [Abstract] ( 86 ) HTML (48 KB)  PDF  (0 KB)  ( 9 ) 15 Study on the dissolution of four effective components in Paracetamol,Aminophenazone Phenacetin,Caffeine and Chlorphenamine Maleate Granules GUO Li-rong； XU Song； WU Yin-shuang； LI Na Objective To establish a method for the dissolution of four effective components in Paracetamol,Aminophenazone Phenacetin,Caffeine and Chlorphenamine Maleate Granules.Methods The paddle method was adopted,the rotation rate was 50 r/min,and the volume of dissolution mediums was 900 ml.Hydrochloric acid solution (0.1N),phosphate buffer (pH=6.8),water and acetic acid-sodium acetate buffer solution (pH=4.0) were adopted as dissolution mediums.Results The dissolution of Caffeine,Paracetamol,Chlorpheniramine Maleate and Aminopyrine were all above 85% of the labelled quantity in 1 h.Conclusion The study provides the experimental basis for the consistency evaluation of the dissolution curves of Paracetamol,Aminophenazone Phenacetin,Caffeine and Chlorphenamine Maleate Granules in vitro. 2020 Vol. 27 (14): 15-20 [Abstract] ( 83 ) HTML (48 KB)  PDF  (0 KB)  ( 9 ) 21 Status and drug therapy of common gastrointestinal diseases XIAO Qiu-ping； LI Ying-meng； ZUO Ke-xuan； ZHENG Long-jin； ZHAN Yang； WAN Jian-hua； LIU Wen-jun Gastrointestinal diseases are common and frequently-occurring diseases that seriously affect the life quality of patients.Additionally,long-term relapse may worsen into a tumor.Therefore,the prevention and treatment of gastrointestinal diseases is particularly important.By searching PubMed,China Knowledge Network and Wanfang databases,this paper conducts a literature survey on the incidence/prevalence of common gastrointestinal diseases and the current status of drug treatment,clarifies the incidence of common gastrointestinal diseases,and analyzes the current status of current drug treatment.Furtheremore,the advantages and disadvantages of the current high-selling drugs are expounded in light of the market sales announced by MENET.The aim is to clarify the high incidence of gastrointestinal diseases and discuss better treatment measures,provide a basis for drug development and treatment innovation,and hope to provide reference value for patients,medical care and scientific research personnel. 2020 Vol. 27 (14): 21-25 [Abstract] ( 85 ) HTML (51 KB)  PDF  (0 KB)  ( 11 ) 26 Research progress of PM2.5 on respiratory system injury SUN Jing ； ZHANG Mian In recent years,environmental pollution and haze weather are increasing with the development of industry and the acceleration of urbanization in China.There are more and more inhalable particles in the atmosphere,and the inhalable particles whose aerodynamic diameter is less than or equal to 2.5 μm (PM2.5) do great harm to human body.The increase of PM2.5 in the environment is positively correlated with the increase of the number of patients with respiratory diseases.PM2.5 has the characteristics of small particle size and large specific surface area.It is easy to carry polycyclic aromatic hydrocarbons and other harmful substances and pathogens.If these substances and bacteria are inhaled into the respiratory tract,they can deposit in the bronchi to promote the release of inflammatory factors and destroy the micro ecological balance of the lung,leading to the occurrence or aggravation of a variety of respiratory system diseases such as pneumonia,bronchial asthma,pulmonary fibrosis,lung cancer and chronic obstructive pulmonary disease.Although some studies have showed the relationship of PM2.5 and respiratory diseases,the research foundation is still relatively weak.This paper reviews the effect of PM2.5 on respiratory diseases and the related mechanisms,so as to provide reference for further research. 2020 Vol. 27 (14): 26-29 [Abstract] ( 89 ) HTML (37 KB)  PDF  (0 KB)  ( 14 ) 30 Advances in the value of serum index in early diagnosis of ovarian malignant tumor WANG Zhi-min； LIU Zhi-qiang； GUO Qing-zhi； SUN Li ； SHI Hong-tang For lung cancer,breast cancer,liver cancer,colorectal cancer,pancreatic cancer and many other solid malignancies,serum carbohydrate antigen 125 (CA125),human epididymal protein 4 (HE4),ratio of platelets to lymphocytes (PLR),and the ratio of neutrophil to lymphocytes (NLR) have been widely studied,and their value have been confirmed by a large number of studies,but there have been few studies on ovarian malignancies.Existing studies have found that serum CA125,HE4,PLR and NLR have certain value in the early diagnosis of ovarian malignant tumors,but there is no unified understanding.So far,there is no accepted sensitive indicator for the early diagnosis of ovarian malignancies.The purpose of this review is to summarize the available evidence. 2020 Vol. 27 (14): 30-33 [Abstract] ( 88 ) HTML (41 KB)  PDF  (0 KB)  ( 5 ) 34 Research progress in internal fixation of unstable femoral neck fractures FAN Bing； GAO Shi-chang Femoral neck fractures are a common injury in clinic.Pauwels′ type Ⅲfemoral neck fractures have special biomechanical characteristic,and was known as unstable femoral neck fractures.The main reason of internal fixation failure and nonunion are shear force and varus stress generated between the fracture interfaces.There are various methods of internal fixation to treat unstable femoral neck fractures except to use traditional three cannulated compression screws (CCS),including three cannulated compression screws (CCS) combined with one transverse screw,dynamic hip screw (DHS) combined with de-rotational screw (DS),three cannulated compression screws combined with medial buttress plate,percutaneous compression plate (PCCP) and InterTAN intramedullary nail.Which were reviewed including the biomechanical characteristics,advantages and disadvantages of unstable femoral neck fracture internal fixation,the treatment of nonunion and osteonecrosis of femoral head (ONFH) after surgery,and providing a reference for clinical treatment of unstable femoral neck fractures. 2020 Vol. 27 (14): 34-39 [Abstract] ( 111 ) HTML (60 KB)  PDF  (0 KB)  ( 12 ) 40 Application effect of drug sensitivity test guidance in eradication therapy of Helicobacter pylori CHEN Shao-wen； LI Kai-xue； LIU Ai-jun Objective To explore the application effect of drug sensitivity test guidance in the eradication therapy of Helicobacter pylori.Methods From January 2017 to January 2019,60 patients with Helicobacter pylori infection diagnosed and treated in Kuichong People′s Hospital of Dapeng New District of Shenzhen City were selected as the research objects,according to the method of random number table,the selected patients were divided into the observation group and the control group,30 cases in each group.Both groups were treated with quadruple therapy.The patients in the control group were treated with Bismuth Potassium Citrate Capsules,Omeprazole Enteric Coated Capsules,Amoxicillin Capsules and Clarithromycin according to the doctor′ clinical experience.Patients in the observation group were treated with two antibiotics combined with Omeprazole Enteric Coated Capsules and Bismuth Potassium Citrate Capsules according to the results of drug sensitivity test.The drug sensitivity test results of the observation group were recorded,and the eradication rate and the total incidence rate of adverse reaction of Helicobacter pylori in the two groups after treatment were compared,the therapeutic effect of the two groups was observed.Results Drug sensitivity test results showed that the drug resistances rates of Amoxicillin,Clarithromycin,Metronidazole,Ciprofloxacin and Rifampin were 0.00%,23.33%,80.00%,23.33% and 3.33%,respectively.The eradication rate of Helicobacter pylori in the observation group was 93.33%,which was higher than 66.67% in the control group,the difference was statistically significant (P＜0.05).The total effective rate of the observation group was 96.67%,which was higher than 70.00% of the control group,the difference was statistically significant (P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups (P＞0.05).Conclusion The application and effect of drug sensitivity test guidance in the eradication therapy of Helicobacter pylori is significant,which can improve the eradication rate of Helicobacter pylori,and it is worthy of clinical promotion and application. 2020 Vol. 27 (14): 40-42转64 [Abstract] ( 89 ) HTML (36 KB)  PDF  (0 KB)  ( 13 ) 43 Application of Shentong Zhuyu Decoction in the treatment of degenerative hip arthritis with blood stasis block after total hip replacement CHEN Wen-hui Objective To evaluate the effect of Shentong Zhuyu Decoction on degenerative hip arthritis with blood stasis block after total hip arthroplasty.Methods A retrospective analysis was made on 40 cases of degenerative hip arthritis with blood stasis block treated in our hospital from February 2018 to October 2019.According to different treatment schemes,they were divided into control group and observation group,20 cases in each group.The control group was treated with total hip replacement.The observation group was treated with total hip replacement and oral Shentong Zhuyu Decoction for 2 weeks 24h after operation.The pain scores and hip function scores of the two groups in different time periods after operation were compared.Results The pain scores of the observation group were (7.12±1.06)points at 1 week,(5.76±1.21) points at 4 weeks and (3.15±1.19) points at 12 weeks after operation,which were lower than those of the control group for (8.65±1.12),(6.42±1.12) and (4.63±0.92) points respectively (P<0.05).The hip joint function score of the observation group was (41.02±4.01) points at 1 week after operation,(62.23±3.15) points at 4 weeks and (82.12±5.29) points at 12 weeks after operation,which were higher than those of the control group (33.13±4.08),(51.23±4.35) and (66.56±5.21) points respectively (P<0.05).Conclusion Oral administration of Shentong Zhuyu Decoction 24h after total hip arthroplasty for degenerative hip arthritis with blood stasis block can significantly improve the microcirculation of soft tissues around the hip joint,reduce the production of inflammatory media and promote the absorption of inflammatory media,significantly reduce the pain after total hip arthroplasty and promote the functional recovery after total hip arthroplasty. 2020 Vol. 27 (14): 43-45 [Abstract] ( 83 ) HTML (32 KB)  PDF  (0 KB)  ( 6 ) 46 Relation of serum pepsinogen and gastrin with Helicobacter pylori related peptic ulcer LING Yun-yang; WU Zhi-fen; HUANG Shao-min; ZHANG Xue-zhi; LIU Shao-jun Objective To investigate the relation of serum pepsinogen Ⅰ(PGⅠ),gastrin (GS) with Helicobacter pylori(Hp) related peptic ulcer.Methods A total of 96 patients with peptic ulcer admitted to Xinjian Hospital of Yichun City hospital from January 2018 to January 2019 were selected.According to the results of gastroscopy,68 cases of positive Hp peptic ulcer were taken as the observation group,and 28 cases of negative Hp peptic ulcer were taken as the control group.The levels of PGⅠand GS of all the patients were detected.The observation group was treated with Omeprazole Enteric-Coated Capsules+Clarithromycin Capsules+Amoxicillin Capsules.The levels of PGⅠand GS were compared between the two groups.The levels of PGⅠand GS in the observation group before and after treatment were compared.After the treatment of HP positive patients,the serum PG Ⅰand GS levels were compared between the negative and non-negative patients.The relation of PGⅠand GS levels with Hp related peptic ulcer was analyzed.Results The levels of PGⅠand GS in the observation group were higher than those in the control group (P<0.05).There were 62 cases of negative conversion in 68 cases of the observation after treatment,the levels of PGⅠand GS in the observation group after treatment were lower than those before treatment (P<0.05).The levels of serum PG Ⅰand GS in patients with Hp turning negative patients were lower than those in patients without Hp turning negative,the differences were statistically significant (P<0.05).Logistic regression analysis showed that serum PGⅠand GS levels were risk factors of positive Hp peptic ulcer (OR>1,P<0.05).Conclusion The levels of serum PGⅠand GS in patients with Hp related peptic ulcer are higher.The PGⅠand GS levels are closely related to the occurrence of Hp related peptic ulcer. 2020 Vol. 27 (14): 46-48 [Abstract] ( 88 ) HTML (34 KB)  PDF  (0 KB)  ( 9 ) 49 Effect of multiple intervention modes via anterior tibial vein approach in the treatment of acute deep venous thrombosis of lower extremity MO Can-jun; ZHANG Zhi-cheng▲ Objective To discuss the effect of multiple intervention modes via anterior tibial vein approach in the treatment of acute deep venous thrombosis of lower extremity.Methods A total of 90 patients with acute deep venous thrombosis of lower extremity from January 2014 to December 2017 treated in our hospital were chosen as research subjects.According to the random number table method,the patients were assigned to conventional group and test group,45 cases in each group.The conventional group took the thrombolytic therapy via popliteal vein approach;the test group took the multiple intervention modes via anterior tibial vein approach.The thrombosis removal effect,incidence of complications,hospital stay and follow-up results were compared.Results The thrombosis removal effect in the test group was better than that in the conventional group,with statistically significant difference (P<0.05).The total incidence rate of complications in the test group (4.44%) was lower than that in the conventional group (24.44%),with statistically significant difference (P<0.05).The hospital stay in the test group was shorter than that in the conventional group,with statistically significant difference (P<0.05).The total incidence rate of adverse events in the test group(2.22%) was lower than that in the conventional group (20.00%),with statistically significant difference (P<0.05).Conclusion For patients with acute deep venous thrombosis of lower extremity,the use of multiple intervention modes via anterior tibial vein approach can improve the thrombosis removal effect,reduce the incidence of complications,shorten the hospital stay,and reduce the incidence rate of adverse events,which is worthy of clinical application. 2020 Vol. 27 (14): 49-51 [Abstract] ( 98 ) HTML (33 KB)  PDF  (0 KB)  ( 12 ) 52 Evaluation of bronchoalveolar lavage through bronchoscopy in the treatment of bronchiectasis complicated with pulmonary infection LUO Xiao-lian Objective To explore the effect of bronchoalveolar lavage through bronchoscopy in the treatment of bronchiectasis complicated with pulmonary infection.Methods From March 2016 to March 2018,60 patients of bronchiectasis complicated with pulmonary infection admitted to our hospital were selected as the subjects of study,they were divided into the control group (30 cases) and the observation group (30 cases) by random number table method,the control group was treated with routine treatment,and the observation group received bronchoalveolar lavage through bronchoscopy.The total effective rate of treatment,blood oxygen content (blood oxygen partial pressure [PaO2],blood oxygen saturation [SaO2],PaO2/FiO2 value) before and after treatment,the rehabilitation and recurrence of infection were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant (93.33% vs.73.33%,P<0.05).After 3 days of treatment,the PaO2,SaO2 and PaO2/FiO2 of the two groups were higher than those before the treatment,the above indexes in the observation group were higher than those of the control group,the differences were statistically significant (P<0.05);the fever time,the antibiotic application time,the time of hospitalization were shorter than those of control group and the number of re visits within half a year was lower than that of the control group,the differences were statistically significant (P<0.05).Conclusion Bronchoalveolar lavage through bronchoscopy is a good treatment for bronchiectasis with pulmonary infection,it can significantly improve the blood oxygen content of the patients and shorten the time of treatment.It is worth further promoting. 2020 Vol. 27 (14): 52-54 [Abstract] ( 86 ) HTML (34 KB)  PDF  (0 KB)  ( 11 ) 55 Clinical effect of Terbutaline combined with Ipratropium Bromide in the treatment of chronic obstructive pulmonary disease XU Jing-yi; WEN Xian; FENG Hai-xuan Objective To investigate the clinical effect of terbutaline combined with Ipratropium Bromide in the treatment of chronic obstructive pulmonary disease (COPD).Methods A total of 153 patients with COPD admitted to our hospital from January 1,2017 to December 31,2018 were enrolled in this study.They were divided into reference group (75 cases) and observation group (78 cases) according to the parity grouping method.The reference group was treated with Terbutaline,the observation group was treated with Terbutaline combined with Ipratropium Bromide.The blood gas index,lung function index and clinical efficacy of the two groups of patients were analyzed and compared.Results After treatment,the levels of arterial oxygon sataration (SaO2) and arterial partial pressure of oxgyon (PaO2) in the observation group were higher than those in the reference group,and the level of arterial pantial pressure of carbon dvoxide (PaCO2) was lower than that in the reference group,the differences were statistically significant (P<0.05).The forced expiratory volume in the first second (FEV1),forced vital capacity (FEV1/FVC) and peak expiratony flow (PEF)levels in the observation group were higher than those in the reference group,the differences were statistically significant (P<0.05).The total effective rate of the observation group was 83.33% (65/78),which was higher than that of the reference group (50.67%),and the difference was statistically significant (P<0.05).Conclusion The clinical effect of Terbutaline combined with Ipratropium Bromide in the treatment of COPD is better,which can improve the blood gas index and lung function index of patients,and play a positive role in the stability of the disease. 2020 Vol. 27 (14): 55-57 [Abstract] ( 92 ) HTML (35 KB)  PDF  (0 KB)  ( 11 ) 58 Effect of Shenmai Injection on the improvement of pulmonary fibrosis related indexes in patients with pneumoconiosis YANG Li-qun; HUANG Sheng; DU Ping Objective To investigate the effect of Shenmai Injection on pulmonary fibrosis in patients with pneumoconiosis.Methods A total of 78 patients with pneumoconiosis treated in Hospital of Occupational Disease Prevention and Control in Shaoguan City from March 2017 to March 2019 were selected as the subjects.The patients were divided into experimental group (n=39) and reference group (n=39) by random digital table method.The patients in reference group adopted the routine symptomatic support of spasmolytic,antitussive,expectorant,oxygen-absorbing,anti-inflammatory,fluid infusion and other pneumoconiosis,and the treatment of tetrandrine tablets,and the patients in the experimental group were treated with Shenmai Injection.After treatment,the improvement of pulmonary fibrosis related indexes such as human type Ⅲprocollagen peptide（PⅢP),type Ⅳcollagen (CⅣ) and type Ⅰprocollagen carboxy terminal peptide(PⅠCP) were compared between the two groups,and the clinical efficacy of the two groups was counted.Results Before treatment,there were no significant differences in pulmonary fibrosis indexes such as PⅢP,CⅣand PⅠCP between the two groups (P>0.05).After treatment,the pulmonary fibrosis indexes such as PⅢP,CⅣand PⅠCP in the two groups were lower than those before treatment (P<0.05),and the pulmonary fibrosis indexes such as CⅣand PⅠCP in the experimental group were lower than those in the control group (P<0.05).The total effective rate of treatment in the experimental group was 93.02%,which was higher than that in the control group (74.36%) (P<0.05).Conclusion Shenmai Injection can effectively improve pulmonary fibrosis,delay the development of pneumoconiosis and improve the clinical effect. 2020 Vol. 27 (14): 58-60 [Abstract] ( 94 ) HTML (33 KB)  PDF  (0 KB)  ( 10 ) 61 Application of non-invasive hemodynamics test in diagnosis and treatment of patients with chronic heart failure LIANG Dong-liang Objective To analyze and discuss the application effect of non-invasive hemodynamic test in the clinical diagnosis and treatment of patients with chronic heart failure (CHF).Methods A total of 106 patients with CHF admitted to our hospital from June 2018 to October 2019 were selected as the research objects.According to the coin method,they were divided into the control group (53 cases) and the research group (53 cases).The control group adopted the conventional observation method,and the research group adopted the non-invasive hemodynamic index detection method.The clinical events,length of stay and cardiac function indexes were compared between the two groups.Results The incidence rates of acute heart failure and cardiac death in the study group were lower than those in the control group,with statistically significant differences (P<0.05).The length of stay in the study group was (14.72±6.14) d,which was shorter than that in the control group (18.85±8.24) d,and the difference was statistically significant (P<0.05).At the time of discharge,the left ventricular ejection fraction (LVEF) level of patients in the study group was higher than that of the control group,the level of brain natriuretic peptide (BNP) was lower than that of the control group,and the walking distance of 6 min was longer than that of the control group,the differences were statistically significant (P<0.05).Conclusion In the process of inpatient treatment of CHF patients,non-invasive hemodynamic test can play a good role in guiding the application of various treatment drugs,thus effectively reducing the risk of acute heart failure faced by patients,improving their heart function,and shorten their hospitalization time. 2020 Vol. 27 (14): 61-64 [Abstract] ( 90 ) HTML (33 KB)  PDF  (0 KB)  ( 9 ) 65 Clinical effect of Bisoprolol combined with Irbesartan in the treatment of patients with chronic heart failure HUANG Xiao-qiang； HU Liang-ming Objective To analyze the clinical effect of Bisoprolol combined with Irbesartan on patients with chronic heart failure.Methods A total of 88 patients with chronic heart failure admitted to our hospital from July 2018 to July 2019 were selected as research objects.According to the single or even number of hospital beds,they were divided into treatment group (44 cases) and control group (44 cases).The control group was treated with Irbesartan.The treatment group was treated with Bisoprolol and Irbesartan.The cardiac function index,blood pressure,serum B-type brain natriuretic peptide (BNP) and high sensitivity C-reactive protein (hs-CRP) levels of the two groups were compared.Results The left ventricular ejection fraction (LVEF) level in the treatment group was higher than that in the control group,with statistical significance (P<0.05),while the left ventricular end diastolic diameter (LVEDD) and left ventricular end systolic diameter (LVESD) levels in the treatment group were lower than those in the control group,with statistical significances (P<0.05).The levels of BNP and hs-CRP in the treatment group were lower than those in the control group after treatment,and the differences were statistically significant (P<0.05).The systolic blood pressure (SBP),diastolic blood pressure (DBP) and pulse pressure difference after treatment in the treatment group were lower than those in the control group,with statistically significant differences (P<0.05).The total effective rate of the treatment group was higher than that of the control group,with statistically significant difference (P<0.05).Conclusion The combination of Bisoprolol and Irbesartan has definite effect on the treatment of chronic heart failure,which can effectively improve the cardiac function index of patients,regulate the blood pressure level of patients,optimize the serum BNP and hs-CRP levels of patients,and has higher application value in clinical practice. 2020 Vol. 27 (14): 65-67转71 [Abstract] ( 82 ) HTML (34 KB)  PDF  (0 KB)  ( 10 ) 68 Application of early intra-aortic balloon counterpulsation in acute myocardial infarction complicated with ventricular septal rupture SU Hang Objective To investigate the clinical value of early intra-aortic balloon counterpulsation in acute myocardial infarction complicated with ventricular septal rupture.Methods A total of 40 cases with acute myocardial infarction complicated of ventricular septal rupture admitted in our hospital from January 2017 to July 2019 were selected as subjects and divided into observation group (20 cases) and control group (20 cases) according to whether they agreed to implement intra-aortic balloon counterpulsation or not.The control group was underwent routine medical treatment.The observation group was applied intra-aortic balloon counterpulsation on the basis of conventional treatment.Then the duration of the booster drug and hospital stay were compared between the two groups.The left ventricular ejection fraction and B-type natriuretic peptide levels were compared before and after the treatment.The treatment results in two group were statisticed.Results The duration of the booster drug and hospital stay in the observation group were shorter than those in the control group,the differences were statistically significant (P<0.05).After treatment,the left ventricular ejection fraction of the observation group was higher than that before treatment and the control group,and the difference was statistically significant (P<0.05).After treatment,the level of B-type natriuretic peptide in the observation group was lower than that before treatment and the control group,and the difference was statistically significant (P<0.05).The survival rate of patients in the observation group was higher than that in the control group,and the difference was statistically significant (P<0.05).The proportion of patients who died or gave up treatment after treatment in the observation group was lower than that in the control group,and the difference was statistically significant (P<0.05).Conclusion For the treatment of acute myocardial infarction with ventricular septal rupture,the application of intraaortic balloon counterpulsation on the basis of conventional treatment can better maintain the stability of circulatory function,so it can improve cardiac function and short the hospitalization time and reduce mortality. 2020 Vol. 27 (14): 68-71 [Abstract] ( 75 ) HTML (36 KB)  PDF  (0 KB)  ( 14 ) 75 Effect of Xuefu Zhuyu Capsules combined with Atorvastatin Calcium Tablets in the treatment of hyperlipidemia of Qi stagnation and blood stasis type LU Feng； BAI Wei-wei； LI Li-feng Objective To explore the effect of Xuefu Zhuyu Capsules combined with Atorvastatin Calcium tablets in the treatment of hyperlipidemia of Qi stagnation and blood stasis type.Methods A total of 96 patients with primary hyperlipidemia of Qi stagnation and blood stasis type diagnosed and treated in the department of Neurology clinic of our hospital from January 2017 to November 2019 were selected as the research objects,and they were divided into the control group (48 cases) and the observation group (48 cases) according to the method of random number table methods.Both groups were given diet guidance and lifestyle adjustment.Patients in the control group were given Atorvastatin Calcium tablets orally,The patients in the observation group were given Xuefu Zhuyu Capsules oral capsule on the basis of the treatment in the control group.Both groups were treated for 2 months.The therapeutic effect,the incidence of adverse reactions,the level of blood lipid and the level of traditional Chinese medicine syndrome symptoms before and after treatment of two months were compared between the two groups.Results The total effective rate of the observation group was 95.83%,which was higher than that of the control group (75.00%),the difference was statistically significant(P＜0.05).The levels of total cholesterol (TC),triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) in the two groups after treatment of two months were lower than those before treatment,and the high density lipoprotein cholesterol (HDL-C) level in the observation group after treatment of two months was higher than that before treatment,the difference was statistically significant (P＜0.05).The level of TC,TG and LDL-C in the observation group after treatment of two months were lower than those in the control group,while the level of HDL-C in the observation group after treatment of two months was higher than that in the control group,the difference was statistically significant (P＜0.05).The traditional Chinese medicine symptom scores of the two groups after treatment of two months were lower than before treatment,and the score of traditional Chinese medicine symptoms in the observation group after treatment of two months was lower than that in the control group,the difference was statistically significant (P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups (P＞0.05).Conclusion The treatment of hyperlipidemia patients of Qi stagnation and blood stasis type with Xuefu Zhuyu Capsules combined with Atorvastatin Calcium Tablets can achieve good clinical effect,which can effectively improve the blood lipid index and traditional Chinese medicine symptoms of patients,and does not increase adverse reactions,it is worthy of clinical promotion and application. 2020 Vol. 27 (14): 75-78 [Abstract] ( 284 ) HTML (39 KB)  PDF  (0 KB)  ( 8 ) 79 Clinical effect of minimally invasive gallbladder-preserving lithotomy in the treatment of gallstone WU Zhao-ping Objective To explore the clinical effect of minimally invasive gallbladder-preserving lithotomy in the treatment of gallstone.Methods A total of 70 patients with gallstone admitted to our hospital from May 2018 to July 2019 were selected as the study objects.The patients were divided into the observation group and the control group by random number table method,35 cases in each group.The control group was treated with laparoscopic cholecystectomy.The observation group was treated with minimally invasive gallbladder-preserving lithotomy.The therapeutic effect of the two groups was observed,and the operation time,hospitalization time,intraoperative hemorrhage and the total incidence rate of complication of the two groups were compared.Results There was no significant difference in the total effective rate between the two groups (P>0.05).There was no significant difference in operation time,hospitalization time and intraoperative bleeding between the two groups (P>0.05).There was no significant difference in the total incidence of postoperative complications between the two groups (P>0.05).Conclusion The clinical effect of minimally invasive gallbladder-preserving lithotomy in the treatment of gallstone is the same as that of laparoscopic cholecystectomy,without increasing complications. 2020 Vol. 27 (14): 79-81 [Abstract] ( 83 ) HTML (34 KB)  PDF  (0 KB)  ( 11 ) 82 Effect and safety of different extent endoscopic papillary balloon dilation for common bile duct stones YE Yan-Qing； LIAO Yue-Guang； XIE Jun； WU Xiong-Jian Objective To investigate the effect and safety of different extent endoscopic papillary balloon dilation in the treatment of common bile duct stones.Methods Data of 119 patients with common bile duct stones admitted to our hospital from January 2016 to December 2017 were retrospectively analyzed.According to the surgery,patients were be divided into the duodenal papilla sphincter incision group (EST group,n=61),the duodenal papilla sphincter small incision + small expansion group (sEST+EPBD group,balloon diameter≤9 mm,n=26),the duodenal papilla sphincter small incision + big expansion group (sEST+EPLBD group,10 mm ≤balloon diameter<15 mm,n=32).The surgical success rate,mechanical lithotripsy rate and recent postoperative complications were analyzed.Results The surgical success rates of sEST+EPLBD group and sEST+EPBD group (96.8%,84.6%) were higher than that in EST group(75.4%),the differences were statistically significant (P<0.05).The rates of mechanical gravel in the sEST+EPLBD group and sEST+EPBD group (12.5%,15.4%) were lower than that of EST group (34.4%),the differences were statistically significant (P<0.05).There were no statistically significant differences in the incidence of postoperative hemorrhage,perforation,pancreatitis and cholangitis among the three groups (P>0.05).Conclusion Endoscopic papillary balloon dilation (balloon diameter<15 mm) is safe and effectiveness in the removal of common bile duct stones. 2020 Vol. 27 (14): 82-85 [Abstract] ( 75 ) HTML (36 KB)  PDF  (0 KB)  ( 8 ) 86 Clinical effect of segmental resection and plastic surgery combined with anastomat procedure for prolapse and hemorrhoid in the treatment of circumferential mixed hemorrhoids ZOU Wei-qiang； LI Fa-hui； LI Jin-yuan Objective To investigate the clinical effect of segmental resection and plastic surgery combined with anastomat procedure for prolapse and hemorrhoid (PPH) in the treatment of circumferential mixed hemorrhoids.Methods Eighty-nine patients with circumferential mixed hemorrhoids treated in our hospital from February 2016 to February 2019 were selected as the research objects,and they were divided into observation group (45 cases) and control group(44 cases) according to the the method of drawing lots.The observation group received segmental resection and plastic surgery combined with PPH,and the control group received segmental resection and plastic surgery.Surgical indicators,pain scores at different times,improvement of anal function,and treatment effect were compared between the two groups.Results The operative time,hospitalization time and wound healing time of the observation group were shorter than those of the control group,and the intraoperative blood loss was less than that of the control group,with statistical differences (P<0.05).The pain scores of patients in the observation group were lower than those in the control group 12 h and 1 week after the surgery,the difference was statistically significant (P<0.05).The improvement of anal function in the observation group was better than that in the control group,and the difference was statistically significant(P<0.05).The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant (P<0.05).Conclusion The clinical effect of circumferential mixed hemorrhoids treated with segmental resection and plastic surgery combined with PPH is very significant,and it is highly safe.It can reduce the pain and improve its anal function.It is worthy of research and promotion. 2020 Vol. 27 (14): 86-88转92 [Abstract] ( 76 ) HTML (34 KB)  PDF  (0 KB)  ( 10 ) 89 Effect comparison of vacuum-assisted rotary resection and para-areolar incision on benign breast mass SHI Wen-ting； WANG Dian-song； HUANG Zhen-hua Objective To compare the effect of vacuum-assisted rotary resection and para-areolar incision on the treatment of benign breast mass.Methods A total of 240 patients with benign breast mass treated in Zhanjiang Maternal and Child Health Hospital from February 2016 to March 2019 were selected as the research subjects.They were divided into the control group (n=120) and the observation group (n=120) according to the random paper method.In the control group,surgery in a para-areolar incision was used,and in the observation group,vacuum-assisted rotary resection was applied.The operation time,intraoperative bleeding volume,treatment cost,clinical breast cosmetic effect,and postoperative complications were compared between the two groups.Results The operation time of the observation group was shorter than that of the control group,the amount of bleeding during the operation was less than that of the control group,the treatment cost was higher than that of the control group,the differences were statistically significant(P<0.05).The excellent and good rate of clinical breast cosmetic effect in the observation group was higher than that in the control group,and the difference was statistically significant (P<0.05).The total incidence of postoperative complications in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Vacuum-assisted rotary resection for patients with benign breast masses has fewer traumas,shorter operation time,better breast cosmetic effect,fewer complications,but higher treatment costs compared with those by a para-areolar incision. 2020 Vol. 27 (14): 89-92 [Abstract] ( 78 ) HTML (35 KB)  PDF  (0 KB)  ( 10 ) 93 Application effect of laparoscopic assisted radical gastrectomy in patients with early gastric cancer XIE Guo-yi； WU Xiao-xia Objective To study the application effect of laparoscopic assisted radical gastrectomy in patients with early gastric cancer.Methods A total of 50 patients with early gastric cancer admitted to Yangchun Hospital of Traditional Chinese Medicine from July 2016 to July 2018 were selected as subjects in the study.They were divided into two groups according to the random number table method,with 25 cases in each group.The patients in the control group were treated with routine laparotomy.The patients in the observation group underwent laparoscopic assisted radical gastrectomy.The surgical conditions,the number of lymph node dissection,the postoperative complications and clinical effect ere compared between the two groups.Results The intraoperative blood loss of patients in the observation group was less than that of the control group,the operative time,the first postoperative feeding time and the hospitalization time were shorter than those in the control group,with statistically significant differences (P<0.05).There was no significant difference in the number of lymph nodes dissected between the two groups (P>0.05).The total incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant (P<0.05).The significant efficiency of the observation group was higher than that of the control group,and the difference was statistically significant (P<0.05).Conclusion The implementation of laparoscopic assisted radical gastrectomy in patients with early gastric cancer radical treatment effect is good,although in terms of number of lymph node cleaning effect has no difference with conventional laparotomy,but the improvement of the patients′ surgery-related indicators is obvious,it can reduce the complication rate to some extent,it can improve the safety of operation and promote the follow-up recovery of patients,so it is worthy to be popularized in clinical application. 2020 Vol. 27 (14): 93-95 [Abstract] ( 82 ) HTML (33 KB)  PDF  (0 KB)  ( 9 ) 96 Comparison of clinical effects between percutaneous radiofrequency ablation and laparoscopic liver cancer resection in the treatment of small hepatocellular carcinoma TAN Li-ye； WANG Jing； XIAO Yang； XIA Ling-yang Objective To compare the clinical effect of percutaneous radiofrequency ablation and laparoscopic liver cancer resection in the treatment of small hepatocellular carcinoma.Methods A total of 100 patients with small hepatocellular carcinoma admitted to our hospital from February 2016 to February 2018 were selected as study objects.They were divided into the observation group (n=50) and the control group (n=50) according to the order of admission.In the observation group,percutaneous radiofrequency ablation was used,while in the control group,laparoscopic liver resection was adopted.Liver function indexes,complications,survival time,and tumor-free survival time were compared between the two groups.Results The levels of alanine aminotransferase (ALT) and aspartate aminotransferase(AST) in the observation group after treatment were lower than those in the control group,and the differences were statistically significant (P＜0.05).The total incidence of complications in the observation group was lower than that of the control group,and the difference was statistically significant (P＜0.05).The survival time and tumor-free survival time of the observation group were longer than those of the control group,with statistical differences (P＜0.05).Conclusion Percutaneous radiofrequency ablation is effective in treating small hepatocellular carcinoma,and can reduce the incidence of complications,prolong the survival time of patients,and improve liver function. 2020 Vol. 27 (14): 96-98 [Abstract] ( 76 ) HTML (31 KB)  PDF  (0 KB)  ( 9 ) 99 Effect of hyperbaric oxygen combined with intensity modulated radiotherapy in the treatment of patients with advanced nasopharyngeal carcinoma ZHONG Hai-lin； FU Qian； WANG Wei-zhong； XING Cheng-liang； LIN Dan-ping； ZHONG Wen Objective To investigate the efficacy of hyperbaric oxygen (HBO) combined with intensity modulated radiotherapy (IMRT) on patients with advanced nasopharyngeal carcinoma (NPC).Methods A total of 80 patients with advanced NPC from June 2016 to June 2018 in the First Hospital of Naval Force of Southern Theater Command PLA were selected as the research object.The patients were divided into the HBO combined with IMRT group (34 cases)and the only IMRT group (46 cases) according to their treatment intention.In the HBO combined with IMRT group,HBO treatment was performed first,then intensity-modulated radiotherapy.The only IMRT group was treated with normal IMRT.After the treatment,the patients′ symptoms and signs,Karnofsky performance state score and acute radiotherapy response were observed and recorded in the two groups,and the nasopharyngeal tumor volume regression was compared between the two groups.Results After the completion of the whole treatment course,the regression rate of neurological symptoms and signs of patients in the HBO combined with IMRT group were higher than those in the only IMRT group,and the difference was also statistically significant (P＜0.05).The improvement effect of quality of life in the HBO combined with IMRT group was better than that in the only IMRT group,with statistically significant differences (P＜0.05).The incidence of acute radioactive side reactions equal or greater than grade 3 in the HBO combined with IMRT group was 17.6%,which was much lower than that in the only IMRT group (41.3%),and there was also a statistically significant difference (P＜0.05).MRI was reexamined 1 month after radiotherapy,and the tumor remission rate of patients in the HBO combined with IMRT group was higher than that in the only IMRT group,and the difference was also statistically significant (P＜0.05).Conclusion For the patients with advanced NPC,HBO combined with IMRT can improve the curative effect of radiotherapy,relieve the neurological symptoms and signs,reduce the incidence of acute side effects of radiotherapy,and improve the quality of life of patients. 2020 Vol. 27 (14): 99-102 [Abstract] ( 56 ) HTML (42 KB)  PDF  (0 KB)  ( 6 ) 103 Effects of Yoga combined with nutritional guidance in pregnancy on maternal and infant outcomes of primiparas TAN Shan-xiong； LI Li； ZHANG Yu-feng； ZHOU Hua Objective To investigate the effects on the maternal and infants outcome by Yoga training and nutrition guidance during pregnancy.Methods From March 2019 to September 2019,130 primiparas with single birth who received routine birth examination before 12 weeks of pregnancy were selected as the control group,and 130 primiparas who participated in Yoga training and nutrition guidance during pregnancy on the basis of the control group were selected as the observation group during the same period,the of maternal and infant outcomes in two groups were analyzed.Results The body weight gain,excess rate of weight gain,gestational diabetes incidence and macrosomia incidence rate in the observation group were lower than those in the control group,and the natural childbirth rate in the observation group was higher than which in the control group.the first,second and total stages of labor of the observation group were shorter than those of the control group,and the differences were statistical significances (P<0.05).There was no significant difference in birth rate of full-term low birth weight infants and asphyxia rate of between the two groups (P＞0.05).Conclusion Yoga training combined with nutrition guidance during pregnancy can effectively control excessive pregnancy weight gain,and reduce gestational diabetes incidence and macrosomia incidence rate,which also can improve the natural childbirth rate. 2020 Vol. 27 (14): 103-106 [Abstract] ( 58 ) HTML (36 KB)  PDF  (0 KB)  ( 4 ) 107 Clinical effect of Azithromycin in the treatment of Mycoplasma pneumonia in children YAN Neng-rong; WU Zu-cheng; PENG Xiang-juan; WANG Si-meng Objective To study the clinical effect of Azithromycin on Mycoplasma pneumonia in children.Methods A total of 100 children with mycoplasma pneumoniae from Shiyan People′s Hospital of Baoan District in Shenzhen City from February 2016 to February 2018 were selected as the study subjects.According to their admission order,they were divided into observation group (50 cases) and control group (50 cases).Patients in the observation group were treated with Azithromycin and patients in the control group were treated with Ambroxol.Treatment indicators,C-reactive protein (CRP),tumor necrosis factor-α (TNF-α),interleukin-6 (IL-6),adverse reactions and therapeutic effect were compared between the two groups.Results The temperature recovery time ([2.01±0.23]d),cough disappearance time ([10.23±1.45]d),symptom improvement time ([6.23±1.22]d) and hospital stay time ([12.22±1.82]d) of the observation group were all shorter than those of the control group ([4.66±1.23],[12.56±1.82],[15.56±1.23]d),with statistically significant differences (P<0.05).After treatment,TNF-α ([11.09±1.66]pg/ml),IL-6 ([12.01±1.24]pg/ml) and CRP([7.01±1.24]mg/L) in the observation group were all lower than those in the control group ([15.76±1.02]pg/ml,[15.99±1.04]pg/ml,and [12.77±1.98]mg/L),with statistically significant differences (P<0.05).The total incidence of adverse reactions in the observation group (2.00%) was lower than that in the control group (22.00%),and the difference was statistically significant (P<0.05).The total effective rate (96.00%) of the observation group was higher than that of the control group (72.00%),and the difference was statistically significant (P<0.05).Conclusion Azithromycin is an effective and safe treatment for Mycoplasma pneumonia in children. 2020 Vol. 27 (14): 107-110 [Abstract] ( 68 ) HTML (38 KB)  PDF  (0 KB)  ( 9 ) 111 Screening results and risk factors of retinopathy in 59 premature infants LUO Fang； ZHANG Xu-ping； WEN Xiao-fang Objective To analyze the screening results and risk factors of retinopathy of premature infants (ROP) in our hospital.Methods A total of 59 premature infants (118 affected eyes) who were admitted to the hospital between May 2018 and May 2019 were retrospectively analyzed.Their general data and data about the disease were collected for screening ROP.According to the screening results and the presence of ROP,the subjects were divided into 52 cases in the normal fundus group and 7 cases in the ROP group.The risk factors were analyzed by Logistic regression analysis.Results Of the 59 premature infants,the detection rate of ROP was 11.86%.The birth weight and gestational age of preterm infants in the ROP group were lower than those of the normal fundus group (P＜0.05).There was no significant difference in the mode of delivery or the number of fetuses between the two groups (P＞0.05).The proportions of oxygen inhalation time ≥72 h,using Dexamethasone,using surfactant and infection in the ROP group were higher than those in the normal fundus group (P＜0.05).There was no significant difference in the proportion of hypoxic encephalopathy,anemia,hyperbilirubinemia or intracranial hemorrhage between the two groups (P＞0.05).Logistic regression analysis indicated that low birth weight (β=1.530,OR=4.618,95%CI=2.088-10.214),small gestational age (β=0.886,OR=2.425,95%CI=1.293-4.550) and oxygen inhalation time ≥72 h (β=1.303,OR=3.680,95%CI=1.620-8.350) were risk factors for ROP (P＜0.05).Conclusion Premature infants with low birth weight,small gestational age and oxygen inhalation time ≥72h are key groups of screening to reduce missed diagnosis.Early detection and intervention should be carried out to reduce the rate of blindness caused by ROP. 2020 Vol. 27 (14): 111-113转117 [Abstract] ( 45 ) HTML (32 KB)  PDF  (0 KB)  ( 11 ) 114 Application effect of virtual reality technology in labor analgesia LIANG Hui-lan； LI Zhi-rong； LIANG Ju Objective To explore the application effect of virtual reality (VR) technology in labor analgesia.Methods 60 cases of full-term parturient women who were admitted to our hospital from March 2018 to February 2019 were selected as research objects,according to random number table method,the patients were divided into experimental group(n=30)and control group(n=30).The experimental group adopted VR technology to assist delivery,while the control group adopted routine observation and nursing of delivery.The labor duration,cesarean section rate,depression score and adverse reactions were compared between the two groups.Results The first labor of the experimental group was shorter than that of the control group,with statistical difference (P<0.05).Visual analogue scale (VAS) score in the experimental group was lower than that in the control group,and the difference was statistically significant (P<0.05).The cesarean section rate of the experimental group was 3.3%,which was lower than that of the control group of 20.0%,with statistical difference (P<0.05).Depression score of the experimental group was lower than that of the control group,and the difference was statistically significant (P<0.05).The incidence of maternal adverse reactions in the control group was 10.0%,which was not statistically significant compared with 6.7% in the experimental group (P＞0.05).Conclusion The application of VR technology in the delivery process of pregnant women can reduce the level of pain and depression during delivery,shorten the duration of the first labor,and improve the rate of vaginal delivery,although there are problems of eye focusing and dizziness and discomfort.The overall clinical effect still has significant advantages. 2020 Vol. 27 (14): 114-117 [Abstract] ( 74 ) HTML (38 KB)  PDF  (0 KB)  ( 11 ) 118 Correlation between the expression level of expression of Decoy receptor 3 in cervical lesions and high-risk human papillomavirus infection WANG Bi-xia； BA Jing； HUANG Chun-you Objective To investigate the correlation between the expression of Decoy receptor 3 (DcR3) in cervical lesions and high-risk human papillomavirus (HR-HPV) infection.Methods The clinical data of 80 patients with cervical cancer and cervical intraepithelial neoplasia (CIN) from January 2017 to June 2018 were retrospectively analyzed.The pathological group was divided into 16 cases of CINⅠgroup and 24 cases of CIN Ⅱgroup.For example,27 patients in the CINⅢgroup and 13 patients in the cervical cancer group.The expression levels of DcR3 in each group were compared.The positive rate of HR-HPV infection and the correlation with the degree of carcinogenesis were analyzed.Results The positive rate of HR-HPV in CIN Ⅰgroup was 43.75%,the positive rate of HR-HPV in CIN Ⅱgroup was 62.50%,the positive rate of HR-HPV in CIN Ⅲgroup was 88.89%.the positive rate of HR-HPV in cervical cancer group was 92.31%.The positive rate of DcR3 in CIN Ⅰgroup was 31.25%,the positive rate of DcR3 in CIN Ⅱgroup was 45.83%,and the positive rate of DcR3 in CIN Ⅲgroup was 66.67%,the positive rate of DcR3 was 76.92% in the cervical cancer group.The Spearman analysis showed that the severity of CIN was positively correlated with HR-HPV infection and DcR3 expression（r=0.426,0.324,P<0.05）;and the expression level of DcR3 in cervical lesions and HRHPV infection is positively correlated（r=0.426,0.324,P<0.05）.Conclusion The high-risk HPV infection and DcR3 expression are positively correlated with cervical cancer and cervical intraepithelial neoplasia.The positive rate of HRHPV and DcR3 increases with the degree of CIN lesion,and the expression level of DcR3 in cervical lesions and HRHPV infection is positively correlated. 2020 Vol. 27 (14): 118-120 [Abstract] ( 63 ) HTML (31 KB)  PDF  (0 KB)  ( 11 ) 121 Effect of Jianpi Shengxue Tablets in the treatment iron deficiency anemia during pregnancy SUN Man； ZHOU Li； LIAO Ping-ying Objective To observe the clinical effect of Jianpi Shengxue Tablets in the treatment of iron deficiency anemia during pregnancy（IDA）.Methods From April 2017 to March 2019,164 patients with IDA treated in our hospital were selected and divided into control group and observation group,82 cases in each group.The control group was treated with Polysaccharide Iron Complex Capsules,and the observation group was treated with Jianpi Shengxue Tablets in basic of the control group.Clinical effect,the blood routine indexes and iron metabolism indexes were compared between the two groups.Results There was no significant difference in red blood cell count (RBC),hemoglobin (Hb),hematocrit (HCT),blood mean red cell volume (MCV) level between the two groups before treatment,but RBC,Hb,HCT and MCV levels in the two groups were higher than those before treatment,and the observation group was higher than the control group,the differences were statistically significant (P<0.05).There was no significant difference levels of serum ferritin (SF),transferrin saturation;transferring saturation (TSAT),serum ferritin content (SI) between the two groups before treatment，the levels of SF,TSAT and SI in the two groups were higher than those before treatment，and the observation group was higher than the control group，the differences were statistically significant (P<0.05).The total incidence of adverse reactions in the observation group was compared with that in the control group,the difference was not statistically significant (P＞0.05).Conclusion Jianpi Shengxue Tablets is effective in the treatment of IDA,which can improve the blood routine index and iron metabolism index of the patients,and promote the rehabilitation of the patients,which is worthy of clinical application. 2020 Vol. 27 (14): 121-123 [Abstract] ( 135 ) HTML (34 KB)  PDF  (0 KB)  ( 12 ) 124 Application of transcervical resection of polyp combined with estrogen and progestin in patients with endometrial polyps JIANG Da-mei Objective To investigate the application of trans-cervical resection of polyps (TCRP) regimen combined with estrogen and progestin in patients with endometrial polyps (EP) and evaluate its clinical effect.Methods A total of 106 patients with EP treated in our hospital from July 2016 to March 2018 were selected as the research subjects.They were divided into control group (n=53) and treatment group (n=53) according to the random number table method.TCRP method was used in the control group.In the treatment group,estrogen and progestin method was added on the basis of the control group.The endometrial thickness,menstrual blood loss,estrogen and progesterone,adverse reactions and recurrence were compared between the two groups.Results The thickness of endometrium at 12 months after surgery in the treatment group was thinner than that in the control group,the pictorial blood loss assessment chart(PBAC) score was lower than that in the control group,and the differences were statistically significant (P<0.05).The estrogen level was lower and the progesterone level in the treatment group was higher compared with those in the control group,the differences were statistically significant (P<0.05).There were no statistical differences in the endometrial thickness,PBAC score,estrogen and progesterone levels of the two groups (P＞0.05).The incidence and recurrence rate of prolonged menstrual period,irregular vaginal bleeding，breast distending pain in the treatment group were lower than those in the control group,and the differences were statistically significant (P<0.05).Conclusion TCRP combined with estrogen and progestin is effective in treating patients with EP,and it is safe and reliable.It can effectively reduce the thickness of the endometrium,promote menstrual recovery,and reduces adverse reactions and disease recurrence,which is worthy of reference. 2020 Vol. 27 (14): 124-126 [Abstract] ( 66 ) HTML (32 KB)  PDF  (0 KB)  ( 12 ) 127 Influence of oral muscle training combined with language cognition training on language rehabilitation in children with mental retardation CAI Juan-e； LI Xiao-le； LI Jia-ni Objective To explore the influence of oral muscle training combined with language cognition training on language rehabilitation in children with mental retardation.Methods Totally 41 children with mental retardation who were treated in our hospital from January 1,2016 to June 30,2019 were selected as the research subjects.They were divided into the control group (n=20) and the observation group (n=21) by random number table methods.Pediatric patients in the control group were treated with language cognitive training alone,and the observation group was treated with oral muscle training combined with language cognition training.The effect of language rehabilitation between the two groups was compared.Results After treatment,the score of language development quotient in the 0-7-year-old pediatric examination table of neuropsychological development in the observation group was higher than that of the control group,and the difference was statistically significant (P＜0.05).After treatment,the scores of language performance development quotient and operational capability development quotient in the observation group were both much higher than those of the control group,with statistical significance (P＜0.05).Conclusion Oral muscle training combined with language cognition training can improve the language development quotient,language performance development quotient,and operational capability development quotient of children with mental retardation,which is helpful for the rehabilitation of the language function,and has high clinical application value. 2020 Vol. 27 (14): 127-129转133 [Abstract] ( 65 ) HTML (33 KB)  PDF  (0 KB)  ( 9 ) 130 Effect of placing Mirena intrauterine device after endometrial resection under the control of Nuoshu impedance in the treatment of adenomyosis WEI Jing Objective To investigate the effect of placing Mirena intrauterine device after endometrial resection under the control of Nuoshu impedance in the treatment of adenomyosis.Methods A total of 60 patients with adenomyosis treated in our hospital from February 2017 to March 2019 were selected as the research subjects.They were divided into the control group (n=30) and the observation group (n=30) according to different treatment methods.In the control group,conventional hot-bulb endometrial resection was used,and in the observation group,Mirena intrauterine device was adopted after endometrial resection under the control of Nuoshu impedance.The clinical efficacy,complications,and menstrual volume,dysmenorrhea score,endometrial thickness,uterine volume before and after treatment of the two groups were compared.Results The total effectiveness rate of clinical treatment in the observation group was higher than that in the control group,and the difference was statistically significant (P＜0.05).There was no significant difference in menstrual volume,dysmenorrhea score,endometrial thickness,or uterine volume between the two groups before treatment (P＞0.05).After treatment,the menstrual volume in the two groups was less than that before treatment,the score of dysmenorrhea degree in the two groups was lower than that before treatment,the thickness of endometrium in the two groups was thinner than that before treatment,and the volume of uterus in the two groups was smaller than that before treatment (P＜0.05).The menstrual volume in the observation group after treatment was less than that in the control group,the score of dysmenorrhea degree in the observation group after treatment was lower than that in the control group,the thickness of endometrium in the observation group after treatment was thinner than that in the control group,and the volume of uterus in the observation group after treatment was smaller than that in the control group,and the difference was statistically significant (P＜0.05).There was no statistically significance in the incidence of complications between the two groups (P＞0.05).Conclusion The clinical effect of Mirena intrauterine device after endometrial resection under the control of Nuoshu impedance in the treatment of adenomyosis is obvious,and the improvement of symptoms are better,which is worthy of clinical promotion and application. 2020 Vol. 27 (14): 130-133 [Abstract] ( 92 ) HTML (33 KB)  PDF  (0 KB)  ( 8 ) 134 Diagnostic value of procalcitonin in the treatment of pelvic inflammatory disease FANG Dan-mei； LIN Xiao-jin Objective To investigate the diagnostic value of procalcitonin (PCT) in the treatment of pelvic inflammatory disease.Methods A retrospective analysis was conducted on 120 patients with suspected pelvic inflammatory disease admitted to our hospital from June 2017 to May 2019 were enrolled in the study.The levels of serum PCT and C-reactive protein (CRP) before and after treatment were measured by automatic biochemical analyzer.Specificity,positive predictive value,negative predictive value,and accuracy of PCT and CRP in the diagnosis of pelvic inflammatory disease.Results Of the 120 patients with suspected pelvic inflammatory disease had definite pathogen infection after laboratory examination (all patients had typical clinical symptoms and signs of pelvic inflammatory disease).Finally,49 patients were diagnosed with pelvic inflammatory disease by laparoscopy and 71 patients with non-pelvic inflammatory disease.Serum PCT examination results confirmed 54 patients with pelvic inflammatory disease,including 16 false positives;serum CRP examination results confirmed 51 patients with pelvic inflammatory disease,including 25 false positives.The sensitivity,positive predictive value,negative predictive value and accuracy of PCT diagnosis of pelvic inflammatory disease were higher than serum CRP,the difference was statistically significant (P<0.05).Conclusion PCT has a high diagnostic value for pelvic inflammatory disease and can be used to guide clinical rational selection of treatment options. 2020 Vol. 27 (14): 134-136转140 [Abstract] ( 60 ) HTML (33 KB)  PDF  (0 KB)  ( 12 ) 137 Clinical effect of laparoscopic surgery on ovarian cysts during pregnancy ZHANG Sheng-hua Objective To analyze the effect and safety of laparoscopic surgery on ovarian cysts during pregnancy.Methods A retrospective study was performed on 82 patients with ovarian cysts during pregnancy who underwent surgery in our hospital from January 2017 to December 2018.Patients were divided into the laparoscopic group (n=67)and the open group (n=15) according to the different surgical methods.Intraoperative and postoperative indicators and neonatal outcomes were compared between the two groups.Results The highest proportion of postoperative pathological types in the laparoscopic group were mature teratomas.The operative time,postoperative ventilation time and postoperative hospitalization time of the laparoscopic group were shorter than those in the laparotomy group,and the intraoperative blood loss was less than that of the laparotomy group,with statistically significant differences (P<0.05).There were no significant differences between the two groups in weight,gestational age and Apgar score (P>0.05).Conclusion Laparoscopic surgery for ovarian cyst during pregnancy is safe and effective,and compared with traditional open surgery,it has more advantages.Under the condition of strict evaluation of indications,it can be the first choice for surgical treatment of ovarian cyst during pregnancy. 2020 Vol. 27 (14): 137-140 [Abstract] ( 60 ) HTML (35 KB)  PDF  (0 KB)  ( 9 ) 141 Clinical effect of laser photocoagulation in the treatment of retinal detachment FENG Wei Objective To explore the clinical effect of laser photocoagulation in the treatment of retinal detachment.Methods From August 2016 to April 2019,200 patients with retinal detachment in our hospital were selected as the research objects,and they were divided into the control group (n=100) and the observation group (n=100) according to random number table method.The control group was treated with drug conservative treatment,and the observation group was treated with laser photocoagulation.The visual field changes,visual acuity and intraocular pressure levels,clinical outcomes,and the incidence rates of complication were compared between the two groups.Results The average visual acuity of (MS) and the incidence rates of complication in the observation group were lower than those in the control group,and the average defect value (MD),visual acuity,intraocular pressure and total clinical effective rate in the observation group were significantly higher than those in the control group,the difference was statistically significant(P＜0.05).Conclusion Laser photocoagulation is effective in patients with retinal detachment,the visual acuity is obviously recovered,the postoperative complications are few,and the popularization value is high. 2020 Vol. 27 (14): 141-143 [Abstract] ( 63 ) HTML (33 KB)  PDF  (0 KB)  ( 11 ) 144 Effect comparison of subconjunctival injection and intraocular injection in patients with macular edema caused by uveitis ZHANG Qi Objective To compare the effect of subconjunctival injection and intraocular injection in patients with macular edema caused by uveitis.Methods A total of 72 patients with macular edema caused by uveitis who were treated in our hospital from January 2018 to March 2019 were selected.All patients were randomly divided into the control group (n=36) and the study group (n=36).Patients in the control group received Triamcinolone by subconjunctival injection;and patients in the study group received Triamcinolone by intraocular injection.The optimal corrected visual acuity,macular fovea thickness,and therapeutic effect of patients in two groups were compared.Results The optimal corrected visual acuities in the study group were higher than those in the control group at 1,2,and 3 months after operation with statistical significance (P<0.05).The thickness of macular fovea was thinner than that of the control group at 1,2,and 3 months after operation,and the differences were statistically significant (P<0.05).The total effect rate of the study group was higher than that of the control group,and the difference was statistically significant (P<0.05).Conclusion Intraocular injection of triamcinolone in patients with macular edema due to uveitis can improve the treatment effect,and promote the correction of patient′s vision,which has high clinical application value. 2020 Vol. 27 (14): 144-146 [Abstract] ( 78 ) HTML (31 KB)  PDF  (0 KB)  ( 12 ) 147 Effect of the filling degree of root canal treatment on the treatment effect of patients with acute pulpitis XU Xin Objective To study the effect of the filling degree of root canal therapy on the treatment effect of patients with acute pulpitis.Methods A total of 100 patients with acute pulpitis admitted to our hospital from January 2018 to June 2019 were enrolled in the study.They were divided into two groups according to the random sampling method,50 cases in each group.All patients underwent root canal therapy.On this basis,the control group used roots tube underfill filling method,the study group used the root tube proper filling method.The clinical effect,psychological status score and quality of life score before and after treatment were compared between the two groups.Results The total effective rate of clinical treatment in the study group was higher than that of the control group (P<0.05).There were no significant differences in self-rating anxiety scale (SAS),self-rating depression scale (SDS) scores between the study group and the control group before treatment (P>0.05).The SAS and SDS scores of the two groups after treatment were lower than those before treatment (P<0.05).After treatment,the SAS,SDS scores of the study group were lower than those of the control group (P<0.05).There were no significant differences between the two groups before and after treatment in the scores of quality of life (P>0.05).The scores of quality of life after treatment in the two groups were higher than those before treatment (P<0.05).After treatment,the scores of quality of life in the study group were higher than those in the control group (P<0.05).Conclusion The method of filling the root canal in patients with acute pulpitis can significantly improve the clinical treatment effect,can significantly alleviate its negative emotions and improve its quality of life,and has important value. 2020 Vol. 27 (14): 147-149 [Abstract] ( 74 ) HTML (31 KB)  PDF  (0 KB)  ( 10 ) 150 Application value of transabdominal and transvaginal superbmicro-vascular imaging color Doppler ultrasound in uterine scar pregnancy LI Cai-ping； HUANG Chun-rong； YE Shan-yu； HE Xiao-yan； GONG Yan-tian； JIANG Qi-yao Objective To investigate the application value of transabdominal and transvaginal superbmicro-vascular imaging color Doppler ultrasound (referred to "transabdominal ultrasound combined with transvaginal ultrasound") in uterine scar pregnancy.Methods A total of 96 patients with suspected uterine scar pregnancy admitted to Huangjiang Hospital of Dongguan City,Guangdong Province from July 18,2016 to July 18,2019 were selected as the research objects.All the patients were diagnosed by transabdominal superbmicro-vascular imaging color Doppler ultrasound (referred to "transabdominal ultrasound") and transvaginal superbmicro-vascular imaging color Doppler ultrasound (referred to "transvaginal ultrasound").With the postoperative diagnosis result as the gold standard,the diagnostic accuracy,sensitivity,specificity,misdiagnosis rate and missed diagnosis rate of various examination methods (transvaginal ultrasound,transabdominal ultrasound,transabdominal ultrasound combined with transvaginal ultrasound) were compared.Results The diagnostic accuracy of transabdominal ultrasound combined with transvaginal ultrasound in patients with simple pregnancy cystic type,mixed mass type and uterine scar pregnancy were higher than those of transabdominal ultrasound and transvaginal ultrasound,and the differences were statistically significant (P<0.05).The sensitivity and specificity of transabdominal ultrasound combined with transvaginal ultrasound were higher than those of transabdominal ultrasound and transvaginal ultrasound,and the rates of missed diagnosis and misdiagnosis were lower than those of transabdominal ultrasound and transvaginal ultrasound,with statistically significant differences (P<0.05).Conclusion The diagnostic accuracy,sensitivity and specificity of transabdominal ultrasound combined with transvaginal ultrasound in patients with uterine scar pregnancy are higher,which is worthy of clinical application 2020 Vol. 27 (14): 150-153转157 [Abstract] ( 58 ) HTML (43 KB)  PDF  (0 KB)  ( 15 ) 154 Analysis of 64-slice spiral CT imaging signs and characteristics in patients with blunt abdominal cavity perforation and mesentery injury WU Zhao-liang; TU Wei-lan; ZOU An-min Objective To investigate the imaging signs and characteristics of 64-slice spiral CT in patients with blunt abdominal cavity perforation and mesentery injury.Methods A retrospective analysis of the date of 132 patients with blunt abdominal trauma admitted into our hospital from April 2015 to June 2017 was conducted.According to the injuries of patients,they were divided into the control group (n=65,blunt organ injury confirmed by surgery,without cavity perforation and mesenteric injury) and the observation group (n=67,with cavity perforation and mesenteric injury confirmed by surgery).Patients of both groups were examined with 64-slice spiral CT.The detection of CT signs of abdominal cavity or retroperitoneal pneumatosis,mesenteric thickening,intestinal wall thickening,increased mesangial density,increased abdominal fat gap density and peritoneal thickening were compared.The direct CT imaging signs of blunt abdominal cavity perforation and mesentery injury were analyzed.Results The abdominal cavity or retroperitoneal pneumatosis,mesenteric thickening,intestinal wall thickening,increased mesenteric density,increased abdominal fat gap density,and peritoneal thickening detection rates in the observation group were higher than those in the control group,and the differences were statistically significant (P<0.05).The direct CT signs of patients with blunt abdominal cavity perforation and mesenteric injury were pneumatosis in the abdominal cavity or retroperitoneum,increased density of the abdominal fat gap,and intestinal wall thickening.Conclusion The 64-slice spiral CT imaging features of blunt abdominal cavity perforation and mesenteric injury are manifested as abdominal or retroperitoneal pneumatosis,mesenteric thickening,intestinal wall thickening,increased mesenteric density,increased abdominal fat gap density,and peritoneal thickening,etc.,which are beneficial for diagnosis. 2020 Vol. 27 (14): 154-157 [Abstract] ( 58 ) HTML (36 KB)  PDF  (0 KB)  ( 9 ) 158 Comparison of the application value of magnetic resonance imaging and computed tomography in the diagnosis of senile multiple cerebral infarction LI Zeng-you Objective To compare the value of magnetic resonance imaging (MRI) and computed tomography (CT)imaging in the diagnosis of senile multiple cerebral infarction.Methods From January 2019 to September 2019,50 elderly patients with multiple cerebral infarction were enrolled in our hospital.All patients were examined by MRI and CT.The detection rate of cerebral infarction,the detection status and time of cerebral infarction,the number and area of cerebral infarction were compared between the two methods at different time of onset.Results The detection rate of MRI was higher than that of CT within 24h and 24-72 h after cerebral infarction,the total detection rate was higher than that of CT (P＜0.05).The detection rate of MRI in patients with cerebellum,parietal lobe and basal cerebral infarction was higher than that of CT (P＜0.05).The time of MRI examination was shorter than that of CT,the number of cerebral infarction lesions of MRI was more than that of CT,the detection area of cerebral infarction lesions of MRI was significantly smaller than that of CT (P＜0.05).Conclusion The practical value of MRI imaging in the diagnosis of senile multiple cerebral infarction is significantly higher than CT. 2020 Vol. 27 (14): 158-160 [Abstract] ( 61 ) HTML (31 KB)  PDF  (0 KB)  ( 11 ) 161 Clinical effect of tongxuan acupuncture combined with vestibular rehabilitation training in the treatment of vestibular migraine LIU Ya-fen; ZHAO Zhen; ZHANG Shui-sheng ; SUN Li Objective To explore the clinical effect of tongxuan acupuncture combined with vestibular rehabilitation training in the treatment of vestibular migraine.Methods A total of 80 patients with vestibular migraine who were admitted to our hospital from June 2018 to June 2019 were selected as the research objects,and they were divided into the control group and the treatment group according to the random number table method,40 cases in each group.Patients in the control group were given vestibular rehabilitation training,and patients in the treatment group were given tongxuan acupuncture combined with vestibular rehabilitation training.The Berg balance scale (BBS),vestibular symptom index (VSI),vertigo symptom,function and quality of life (DHI) scores before and after treatment in the two groups of patients were observed,and the treatment effect and recurrence rate of the two groups were compared.Results The total effective rate of treatment in the treatment group was 86.8%,which was higher than that in the control group accounting for 64.8%,and the difference was statistically significant (P<0.05).The BBS scores of the two groups of patients after treatment were higher than those before treatment,the VSI scores were lower than those before treatment,the DHI scores were lower than those before treatment,and the differences were statistically significant (P<0.01).The BBS score of the treatment group after treatment was higher than that of the control group,the VSI score was lower than that of the control group,the DHI score was lower than that of the control group,and the differences were statistically significant (P<0.05).After 1 month of follow-up,the recurrence rate of the patients in the treatment group was 2.6%,and the recurrence rate of the patients in the control group was 5.4%.There was no statistically significant difference in the recurrence rate between the two groups (P>0.05).Conclusion Tongxuan acupuncture combined with vestibular rehabilitation training is ideal for the treatment of vestibular migraine,which can effectively improve the quality of life,improve the symptoms of vertigo,and facilitate the rehabilitation of vestibular function. 2020 Vol. 27 (14): 161-164 [Abstract] ( 75 ) HTML (37 KB)  PDF  (0 KB)  ( 8 ) 165 Observation on the effect of moxibustion combined with health education on sleep disorder of college students LI Quan-yao; CHEN Hong; LONG Zheng-lin; LIU Xiao-zhu; XIA Cong ; ZHANG Ting-ting Objective To investigate the curative effect of moxibustion combined with health education on sleep disorders of college Students.Methods A total of 36 college students who met the diagnostic criteria for sleep disorders from May to July,September to December,2018 in our university were selected as the study subjects,and they were divided into the treatment group (19 cases) and the control group (17 cases) according to stratified randomization.The control group adopted the method of healthy lifestyle publicity and education.In the treatment group,on the basis of health education in the control group,Baihui and Yongquan points were selected for moxibustion.The each component factor,total score and clinical efficacy of Pittsburgh sleep questionaire index (PSQI) were compared between the two groups.Results After treatment,the scores of sleep quality,the time of falling asleep,the length of sleeping,sleep disorder and daytime functional activity in the two groups were obviously lower than those before treatment,the difference was statistically significant (P＜0.01).The scores of sleep quality and the length of sleeping in the treatment group after treatment were lower than those in the control group,and the difference was statistically significant (P＜0.05).The total score of PSQI in the two groups after treatment was significantly lower than that before treatment,and the difference was statistically significant (P＜0.05).The total score of PSQI in the treatment group after treatment was lower than that in the control group,and the difference was statistically significant (P＜0.05).There was no significant difference in the total effective rate between the treatment group (94.7%) and the control group (70.59%) (P＞0.05).Conclusion Moxibustion of Baihui and Yongquan points combined with health education can significantly improve the sleep disorders of college students with heart and kidney disorders,and the effect of this is better than only using health education，and it is worthy of clinical promotion and application. 2020 Vol. 27 (14): 165-168 [Abstract] ( 55 ) HTML (47 KB)  PDF  (0 KB)  ( 10 ) 169 Application effect of Simo Decoction after hysteromyoma operation ZOU Guo-yao Objective To observe the application effect of Simo Decoction after hysteromyoma operation.Methods A total of 100 cases of hysteromyoma admitted to our hospital from August 2017 to March 2019 were selected as the study subjects.According to the random number table method,they were divided into intervention group (50 cases) and control group (50 cases).The control group nceived routine nursing.The intervention group used Simo Decoction on the basis of routine nursing.The intestinal function recovery index,hospitalization time,total complication rate and total nursing satisfaction were compared between the two groups.Results The defecation time,exhaust time,recovery time of bowel sounds and hospitalization time in the intervention group were shorter than those in the control group.The total rate of complications in the intervention group was lower than that in the control group.The total nursing satisfaction of the intervention group was higher than that of the control group.The differences were statistically significant (P<0.05).Conclusion On the basis of routine nursing,the use of Simo Decoction to regulate the intestinal tract of patients with hysteromyoma after surgery,the effect is very significant.Simo Decoction can not only help patients with venting and defecation as soon as possible,but also quickly restore the gastrointestinal function of patients.It can also reduce the incidence of postoperative complications,and improve patients′ satisfaction with nursing intervention. 2020 Vol. 27 (14): 169-171 [Abstract] ( 68 ) HTML (32 KB)  PDF  (0 KB)  ( 12 ) 172 Clinical effect of Banxia Xiexin Decoction in the treatment of children with dyspepsia YI Peng-fei Objective To explore the clinical effect of Banxia Xiexin Decoction in the treatment of children with dyspepsia.Methods Totally 90 children with dyspepsia diagnosed and treated in our hospital from August 2018 to August 2019 were selected as the research objects,and randomly divided into experimental group and control group,45 cases in each group.In the control group,children were treated with Western drugs,and in the experimental group,Banxia Xiexin Decoction on the basis of the control group was added.The clinical efficacy,symptom scores before and after treatment and incidence of adverse reaction of the two groups were compared.Results The total effective rate of treatment in the experimental group was 91.1%,which was higher than that in the control group accounting for 64.4%,and the difference was statistically significant (P<0.05).There were no statistically significant differences in symptom scores between the two groups of children before treatment (P>0.05).After treatment,the scores of upper abdominal pain,early satiety,belching,nausea,vomiting and burning sensation in the upper abdomen of the two groups were lower than those before treatment,and the differences were statistically significant (P<0.05).The scores of upper abdominal pain([1.1±0.2) points],early satiety ([1.0±0.4]points),belching ([1.3±0.4]points),nausea ([1.2±0.6]points),vomiting ([1.0±0.3]points) and burning sensation in the upper abdomen ([0.9±0.3]points) of the experimental group were lower than those of the control group ([2.5±0.8],[1.8±0.6],[2.5±0.9],[2.0±1.1],[1.9±0.9],[1.4±1.1]points),and the differences were statistically significant (P<0.05).The total incidence rate of adverse reactions in the experimental group was 4.4%,which was lower than that in the control group accounting for 22.2%,and the difference was statistically significant (P<0.05).Conclusion The clinical effect of Banxia Xiexin Decoction is definite in the treatment of children with dyspepsia.It can accelerate the recovery of intestinal function in children with high safety,which is worthy of promotion and application. 2020 Vol. 27 (14): 172-174 [Abstract] ( 65 ) HTML (33 KB)  PDF  (0 KB)  ( 12 ) 175 Discussion on clinical trial management system for Good Clinical Practice requirements GUO Zuo-bing; ZAN Ying The drug clinical trial management plays a crucial role in the control of clinical trial data and quality.The“paper quality” of clinical trial data is an important reason for the low efficiency,hard quality control and energy waste of clinical trials.By exploring the qualifications of researchers in drug clinical trial institutions,electronic information management of project review and trial funding,and the need for electronic information management of subjects,test drugs,biological samples,and clinical trial data in clinical trial procedures,the development and application of the electronic data management system in China provides support for the construction of the clinical trial management system that meets the domestic GCP requirements. 2020 Vol. 27 (14): 175-177 [Abstract] ( 61 ) HTML (33 KB)  PDF  (0 KB)  ( 12 ) 178 Application effect of secondary pre-examination and triage management mode in improving outpatient quality management LI Hui-zhen Objective To explore the application effect of the secondary pre-examination and triage management mode in improving the outpatient quality management.Methods A total of 400 outpatients who were treated in our hospital from June 2018 to January 2019 were randomly divided into the control group (using the conventional triage management mode) and the observation group (using the secondary pre-examination and triage management mode),200 cases in each group.The humanistic care scores,professional level scores,waiting time scores,medical environment scores,visit procedure scores,triage accuracy,medical dispute rates,nursing quality scores,and emotional scores (self-rating anxiety scale [SAS],self-rating depression scale [SDS]) were compared between the two groups.Results The humanistic care score,professional level score,waiting time score,medical environment score,visit procedure score,and nursing quality score in the observation group were all higher than those in the control group,the differences were statistically significant (P<0.05).After nursing,the SAS and SDS scores in the observation group were lower than those in the control group,the differences were statistically significant (P<0.05).The triage accuracy in the observation group (97.5%)was higher than that in the control group (73.0%),the difference was statistically significant (P<0.05).The medical dispute rate in the observation group (1.00%) was lower than that in the control group (8.50%),the difference was statistically significant (P<0.05).Conclusion The secondary pre-examination and triage management mode can effectively improve the satisfaction of outpatients and improve the quality of outpatient triages,which is worth promoting. 2020 Vol. 27 (14): 178-180转184 [Abstract] ( 63 ) HTML (34 KB)  PDF  (0 KB)  ( 14 ) 181 Application effect of nosocomial infection control supervision and management in reducing hospital infection LIN Qiu-wei ； LIANG Qun Objective To explore the application effect of nosocomial infection control supervision and management in reducing nosocomial infection.Methods A total of 850 inpatients in our hospital from December 2018 to may 2019 were selected as the research objects.Patients were divided into observation group (n=420) and control group (n=430)according to the different supervision and management schemes of infection control.The control group adopted routine nursing and treatment plan and worked according to the standard of hospital infection prevention.On the basis of the control group,the observation group was supervised and managed by the nosocomial infection control medical staff.The incidence of nosocomial infections,the quality of work quality of medical staff,and the detection rate of multidrug-resistant organisms (MDROs) were compared between the two groups.Results The incidence of nosocomial infection in the observation group was lower than that in the control group,and the difference was statistically significant (P<0.05).The scores of theoretical knowledge,aseptic concept,service quality,hand hygiene and total score of work quality in sense control of the medical staff in the observation group were higher than those in the control group,with statistically significant differences (P<0.05).The detection rates of Staphylococcus aureus,Escherichia coli and Klebsiella pneumoniae MDROs in the observation group were all lower than those in the control group,with statistically significant differences (P<0.05).Conclusion The supervision of medical staff can significantly reduce the incidence of nosocomial infections,improve the quality of medical staff,and reduce the detection rate of MDROs. 2020 Vol. 27 (14): 181-184 [Abstract] ( 62 ) HTML (35 KB)  PDF  (0 KB)  ( 13 ) 185 Analysis of the strategy of refined management applied to hospital management LIU Ying The hospital is a relatively special institution.It is a place for the treatment and rehabilitation of patients.The hospital has more patients per day,and the flow of people is large,which is prone to various adverse events.In the process of rapid development,the hospital needs to strengthen the management of the hospital so that the work of the hospital can be carried out in an orderly and smooth manner,ensuring that patients in each department can receive diagnosis and treatment in time,providing a good medical environment for patients,so that patients can has a high degree of satisfaction for hospital.This paper mainly summarizes the strategies used in the management of refined management. 2020 Vol. 27 (14): 185-187 [Abstract] ( 55 ) HTML (32 KB)  PDF  (0 KB)  ( 10 ) 188 Research on the status quo and problems of the cultivation of nursing graduates in China WEN Hong-juan； WEN Kuo； QIU Yong-liang； CHENG Zhi-fang； ZHANG Yu-wei The current cultivation status quo of nursing graduates in China is expounded,and the advantages and disadvantages for the nursing cultivation are analyzed,in order to improve and increase the cultivation method of nursing graduates.Through the employment department and graduate school of a medical college in Jilin province,the information on the graduation rate and employment rate of nursing majors from 2015 to 2019 was obtained.Data analysis found that the number of graduates of nursing graduates increased year by year.Although the graduation rate fluctuated,it remained at a relatively high level.Insufficient innovation ability,imperfect faculty structure,and inadequate specialist refinement are the main problems that restrict the development of cultivation.Reasonable strategies should be formulated for these problems. 2020 Vol. 27 (14): 188-190转204 [Abstract] ( 66 ) HTML (38 KB)  PDF  (0 KB)  ( 7 ) 191 Exploration and practice of comprehensive experimental teaching mode of tissue engineering LI Li ； TANG Li-Bo Tissue engineering,as a new subject,is becoming an important part of clinical medicine with the development of science and technology.Therefore,it is necessary to explore the teaching mode of tissue engineering course for undergraduate students majoring in clinical medicine.With the teaching goal of training innovative talents for clinical medicine specialty,taking the preparation and transplantation of tissue engineering organs-periosteum as the main line,this study combines many dispersive experiments into serial comprehensive experiments.The teaching effect and the completion of teaching objectives are evaluated according to the feedback and investigations from the students and teachers,as well as the teaching advices from the supervisors. 2020 Vol. 27 (14): 191-194 [Abstract] ( 59 ) HTML (37 KB)  PDF  (0 KB)  ( 11 ) 195 A case report of lethal dose Colchicine poisoning and treatment LU Li-li ； KONG De-hua； WANG Jian-bin ； ZHANG Ze-hua Colchicine is mainly used clinically for the treatment of gout,but its therapeutic dose is not much different from that of poisoning.Colchicine is rapidly absorbed after oral administration,and after poisoning,it will inhibit the mitosis of the cells,resulting in damage to multiple organ functions and even death.Colchicine has no effective antidote,early gastric lavage and symptomatic support treatment is necessary.This patient suffered from multiple organ failure after taking over-lethal dose of Colchicine.After continuous support therapy such as continuous renal replacement therapy,anti-infection,non-invasive ventilation,application of cell colony stimulating factor,blood product infusion,nutritional support,the patient successfully discharged. 2020 Vol. 27 (14): 195-197 [Abstract] ( 63 ) HTML (27 KB)  PDF  (0 KB)  ( 13 ) 198 One case of subserosa pneumatosis cystoids intestinalis LI Rui Pneumatosis cystoides intestinalis (PCI) is characterized by gas-filled cysts in the gastrointestinal submucosa or subserosa,with the development and popularization of imaging techniques and endoscopy,reports of PCI are gradually increased,but most reports are submucosa.Endoscopic examination of a simple subserosa PCI is difficult to find,and there are few reports.The main symptoms of PCI can be abdominal pain,hematochezia,diarrhea,etc,but there is no recognizable specificity.The pneumoperitoneum may appear after rupture of the cyst,and X-ray show free gas under diaphragm,which can be painless perforation.It is safe and intuitive to make a diagnosis by CT and other imaging examinations,depending on the patient′s clinical performances,a multidisciplinary consultation may be required,and then select treatment. 2020 Vol. 27 (14): 198-200 [Abstract] ( 52 ) HTML (31 KB)  PDF  (0 KB)  ( 11 ) 201 Application effect of high quality nursing intervention in phacoemulsification ZHU Jing Objective To investigate the application effect of high quality nursing intervention in phacoemulsification.Methods A total of 78 patients with phacoemulsification who were admitted to our hospital from January to 2018 June were selected and divided into control group and observation group according to random number table,39 cases in each group.The control group was given routine nursing,and the observation group was given high quality nursing intervention based on control group.The best corrected visual acuity,quality of life of visual function,medication compliance,nursing satisfaction,and postoperative complications were compared between two groups.Results After surgery for 1 month,the best corrected visual acuity of two groups was higher than that after surgery for 1 day,the best corrected visual acuity of observation group after surgery for 1 day and 1 month was higher than that of control group,the difference were statistically significant (P<0.05).After surgery for 3 months,the scores of items of the national eye institute 25-item visual function questionnaire (NEI-VFQ-25) scale in observation group were higher than those in control group,the differences were statistically significant (P<0.05).The total medication compliance and nursing total satisfaction of observation group were higher than those of control group,and the total incidence of complications in observation group was lower than that in control group,the differences were statistically significant (P<0.05).Conclusion High quality nursing intervention for patients with phacoemulsification can increase corrected effects of visual acuity,improve medication compliance and nursing satisfaction,prevent complications,and enhance quality of life of visual function. 2020 Vol. 27 (14): 201-204 [Abstract] ( 62 ) HTML (36 KB)  PDF  (0 KB)  ( 10 ) 205 Application effect of comprehensive nursing intervention on voluntary urination after gynecological abdominal surgery WU Jian-ling Objective To analyze the effect of comprehensive nursing intervention on voluntary urination after gynecological abdominal surgery.Methods Sixty-eight patients who were received gynecological abdominal surgery in our hospital from June 2018 to May 2019 were selected as subjects.They were randomly divided into the control group and the study group,34 cases in each group.The control group was given conventional nursing,while the study group was given comprehensive nursing intervention.The total effective rates of voluntary urination,time of first urination,volume of first urination,and quality of life before and after nursing intervention were compared between the two groups.Results The total effective rate of voluntary urination in the study group was higher than that in the control group,with statistical difference (P<0.05).The time of first urination in the study group was earlier than that in the control group,the volume of first urination in the study group was greater than that in the control group,with statistical differences(P<0.05).There were no significant differences in physical function,social function,psychological function,material life scores and total quality of life scores between the two groups before nursing intervention (P＞0.05).The physical function,social function,psychological function,material life scores,and total quality of life scores of the two groups were higher than those before the intervention,with statistical differences (P<0.05).After nursing intervention,the physical function,social function,psychological function,material life score and total quality of life score of the study group were higher than those of the control group,with statistical differences (P<0.05).Conclusion Comprehensive nursing intervention can promote the voluntary urination of patients undergoing gynecological abdominal surgery after removal of urinary catheter,improve the clinical effect,enable patients to achieve voluntary urination as soon as possible,increase the volume of urination,and improve the quality of life of patients. 2020 Vol. 27 (14): 205-207转211 [Abstract] ( 54 ) HTML (33 KB)  PDF  (0 KB)  ( 11 ) 208 Application effect of continuous nursing mode in thrombolytic therapy for patients with acute cerebral infarction FU Qiao-yuan Objective To explore the application effect of continuous nursing mode in thrombolytic therapy for patients with acute cerebral infarction (ACI).Methods A total of 60 patients with ACI treated by thrombolysis in our hospital from January 2018 to March 2019 were selected as the research objects and divided into control group and observation group according to random number table method,30 cases in each group.The control group was treated with conventional nursing methods and the observation group was treated with continuous nursing mode.National Institute of Health stroke scale (NIHSS) score,simplified Fugl-Meyer (FMA) score,functional independence measure (FIM) score,modified Barther index score,compliance behavior of patients,incidence of complications and other related indicators before and after treatment of the two groups were compared.Furthermore,the effect of continuous nursing mode on patients undergoing thrombolytic therapy for ACI was analyzed.Results The NIHSS score of the two groups of patients after nursing were lower than those before nursing,and their FMA score,modified Barther index score and FIM score were higher than those before nursing,with statistical differences (P<0.05).Moreover,the NIHSS score of the observation group after nursing was lower than that of the control group,and its FMA score,modified Barther index score and FIM score were higher than those of the control group,with statistical differences (P<0.05).The proportion of patients in the observation group who followed doctor′s advice after nursing was higher than that in the control group,and the difference was statistically significant (P<0.05).The incidence of complications in the observation group was lower than that in the control group,with statistical difference (P<0.05).Conclusion Continuous nursing mode has significant effect in the nursing of patients with ACI undergoing thrombolytic therapy.It can reduce complications,promote the recovery of patients′ neurological and limb functions,and improve patients′ daily living ability.It is worthy of clinical reference and application. 2020 Vol. 27 (14): 208-211 [Abstract] ( 68 ) HTML (34 KB)  PDF  (0 KB)  ( 10 ) 212 Application effect of evidence-based nursing in patients with breast cancer surgery ZHU Lei Objective To explore the application effect of evidence-based nursing in patients with breast cancer surgery.Methods A total of 200 cases of breast cancer surgery patients admitted to our hospital from November 2017 to November 2018 were selected as research subjects.According to the random number table method,they were divided into routine nursing concept group (n=100) and evidence-based nursing concept group (n=100).The evidence-based nursing concept group adopts the evidence-based concept nursing method,and the conventional nursing concept group adopts the conventional nursing method.The nursing satisfaction,the time of bedtime after breast cancer surgery,the length of hospital stay,the cost of hospitalization,the psychological score of self-evaluation before and after nursing,and the psychological score of self-evaluation of depression between two groups were compared.Results The nursing satisfaction of the evidence-based nursing concept group was higher than that of the conventional nursing concept group,and the difference was statistically significant (P<0.05).The evidence-based nursing concept group anxiety selfassessment psychological,depression self-assessment psychological scores were lower than those of the conventional nursing concept group,the differences were statistically significant (P<0.05).In the evidence-based nursing concept group,the time of bed-out and hospitalization after breast cancer surgery were shorter than those of the conventional nursing concept group,and the hospitalization cost was lower than that of the conventional nursing concept group,and the differences were statistically significant (P<0.05).Conclusion Evidence-based nursing intervention for breast cancer patients has a significant benefit in promoting breast cancer recovery and reducing their medical burden,and breast cancer patients have higher satisfaction with nursing services and is worthy of clinical recommendation. 2020 Vol. 27 (14): 212-214 [Abstract] ( 61 ) HTML (30 KB)  PDF  (0 KB)  ( 10 ) 215 Application effect of optimizing the nursing process of trauma first aid in trauma patients WANG Shi-jing Objective To discuss the application effect of optimizing the nursing process of trauma first aid in trauma patients.Methods A total of 66 cases of trauma emergency patients admitted to our hospital from March 2018 to March 2019 were selected as the research objects.They were divided into control group (n=33) and observation group (n=33)by order of admission.The control group was used routine first aid nursing process,the observation group was used optimize the process of trauma emergencynursing.The first aid time,success rate and nursing satisfaction of the two groups were compared.Results The vehicle time,triage time,intravenous medication time and treatment time in observation group was shorter than those in control group,the differences were statistically significant (P<0.05).The total success rate of the observation group was 96.97%,higher than 81.82% in control group,the difference was significant(P<0.05).The nursing total satisfaction of observation group was 90.91%,higher than 69.70% in control group,the difference was significant (P<0.05).Conclusion Optimizing the process of trauma first aid nursing can shorten the time of emergency nursing,improve the success rate of treatment and nursing satisfaction,then improve the quality of medicalnursing. 2020 Vol. 27 (14): 215-217 [Abstract] ( 51 ) HTML (31 KB)  PDF  (0 KB)  ( 9 ) 218 Effect of children′s health care on the early growth and development of children aged 1-13 months ZHOU Li Objective To explore the effect of child health care on the early growth and development of children aged 1-13 months.Methods A total of 62 cases of children admitted to our hospital from January 2017 to January 2019 were selected as the research objects.According to the random number table method,they were divided into control group (n=31) and observation group (n=31).The control group was given routine health care,while the observation group was given child health care.The physical development,growth and development and nursing satisfaction of the two groups were compared.Results The physical development of the observation group was higher than that of the control group in head circumference,height and weight (P<0.05),the growth and development scores of the observation group were higher than those of the control group in speech communication,big movements,fine movements and environmental adaptability (P<0.05);the nursing satisfaction scores of the observation group were higher than that of the control group,with statistical differences (P<0.05).Conclusion Child health care for children aged 1 to 13 months can improve their early growth and development,and promote their physical development and growth. 2020 Vol. 27 (14): 218-220 [Abstract] ( 64 ) HTML (32 KB)  PDF  (0 KB)  ( 8 ) 221 Application effect of continuous nursing on elderly patients with unstable angina pectoris and coronary heart disease DING Li Objective To explore the application effect of continuous nursing in elderly patients with（CHD）unstable angina pectoris.Methods A total of 98 elderly patients with（CHD）unstable angina pectoris from November 2017 to may 2019 in our hospital were selected as the research objects.According to the random number table method,they were divided into control group (n=49) and observation group (n=49).The control group used the routine discharge guidance method,and the observation group used the continuous nursing guidance method.The changes of Seattle angina evaluation scale,adverse events and negative emotion score were compared between the two groups.Results After intervention,the score of Seattle angina evaluation scale in the observation group was higher than that before intervention and the control group,the difference was statistically significant (P<0.05);the total incidence of adverse events in the observation group was lower than that in the control group,the difference was statistically significant (P<0.05).The negative emotional score of the observation group was lower than that of the control group in anxiety and depression (P<0.05).Conclusion continuous nursing has a good effect on elderly patients with CHD unstable angina pectoris.It can improve the score of Seattle angina evaluation scale,reduce the occurrence of adverse events,and improve the negative emotions of patients. 2020 Vol. 27 (14): 221-223转227 [Abstract] ( 59 ) HTML (32 KB)  PDF  (0 KB)  ( 11 ) 224 Effect of continuous nursing of Wechat enhanced model on drug compliance after percutaneous coronary intervention in patients with coronary heart disease GUAN De-juan； LI Chun-rong▲ Objective To explore the effect of continuous nursing of wechat enhancement model on drug compliance after percutaneous coronary intervention (PCI) in patients with coronary heart disease (CHD).Methods A total of 99 CHD patients and treated with PCI in our hospital from May 2017 to May 2018 were selected as subjects.The patients were divided into the observation group (n=50) and the control group (n=49) according to random number table method.The control group was given routine nursing,and the observation group was given continuous nursing of Wechat enhancement mode on the basis of the control group.The drug compliance and nursing satisfaction of the two groups were observed and compared at 12 months after PCI.Results At 12 months after PCI,the compliance of the observation group was better than that of the control group,the difference was statistically significant (P<0.05).The nursing satisfaction of the observation group was better than that of the control group,the difference was statistically significant (P<0.05).Conclusion The continuous nursing of Wechat enhanced mode is helpful to improve the compliance and nursing satisfaction of CHD patients after PCI. 2020 Vol. 27 (14): 224-227 [Abstract] ( 64 ) HTML (33 KB)  PDF  (0 KB)  ( 13 ) 228 Application effect of whole-course negative pressure superficial suction combined with intratracheal drip in nursing of laryngeal cancer patients after operation SUN Hui Objective To explore the application effect of whole negative pressure superficial sputum suction combined with intratracheal drip in the nursing of laryngeal cancer patients after operation.Methods From January 2017 to June 2019,30 patients with laryngeal carcinoma treated in our hospital were selected as the observation group,and 30 patients with laryngeal carcinoma who underwent routine manual sputum excretion were taken as the control group.The total incidence of nursing adverse events,disposable tracheal catheter cleanliness score,sputum aspiration compliance rate and satisfaction score were compared between the two groups.Results The total incidence of nursing adverse events in the observation group was 6.67%,which was lower than that in the control group (30.00%),with statistical difference (P<0.05).The cleanliness score of disposable tracheal tube in the observation group was higher than that in the control group,with statistical difference (P<0.05).The total compliance rate of sputum aspiration in the observation group was 93.33%,which was higher than 66.67% in the control group,with statistical difference (P<0.05).The satisfaction score in the observation group was higher than that in the control group,with statistical difference (P<0.05).Conclusion The application effect of whole negative pressure sputum suction combined with intratracheal drip in postoperative nursing of laryngeal cancer is helpful to maintain the cleanliness of the catheter,It has the clinical value of popularization. 2020 Vol. 27 (14): 228-230 [Abstract] ( 65 ) HTML (32 KB)  PDF  (0 KB)  ( 4 ) 231 Application effect of targeted nursing on intracranial hypotension syndrome after craniocerebral tumor surgery ZHANG Zhi-hong Objective To investigate the application effect of targeted nursing on intracranial hypotension syndrome(HIS) after craniocerebral tumor surgery.Methods Eighty patients with meningioma operation in our hospital from November 2017 to July 2019 were selected as the research subjects.They were divided into observation group (n=40)and control group (n=40) according to the random number table method.Patients in the control group received routine nursing intervention,and in the observation group,targeted nursing for the HIS on the basis of the control group was added.The clinical symptoms,the time for the intracranial pressure to return to normal,the time for the headache to disappear,and the time to get up and walk between two group were compared.The proportion of post-clinical symptoms including nausea,vomiting,and dizziness,and postoperative hospital stay were calculated.Results The time for the intracranial pressure to return to normal,the headache disappearance time,and the time to get up and walk in the observation group were shorter than those in the control group,and the differences were statistically significant (P<0.05).After nursing,the incidence of nausea,vomiting,and dizziness were lower than those of the control group,the differences were statistically significant (P<0.05).The postoperative hospital stay in the observation group was shorter than that in the control group,the difference was significant (P<0.05).Conclusion Targeted nursing intervention for patients with HIS after craniocerebral tumor surgery can greatly improve the clinical symptoms,reduce the occurrence of discomfort,and promote early rehabilitation and discharge of patients. 2020 Vol. 27 (14): 231-233 [Abstract] ( 56 ) HTML (32 KB)  PDF  (0 KB)  ( 11 ) 234 Effect of continuous nursing combined with 24-hour ambulatory blood pressure monitoring on blood pressure control and nursing satisfaction in patients with essential hypertension GUAN Shao-bin Objective To explore the effect of continuous nursing combined with 24-hour ambulatory blood pressure monitoring (ABPM) intervention on blood pressure control and nursing satisfaction in patients with essential hypertension.Methods 100 patients with essential hypertension in our hospital from April 2017 to January 2018 were selected and randomly divided into control group and experimental group,50 cases in each group.The control group received routine nursing of hypertension and systematic health education.On this basis,the experimental group was given continuous nursing intervention combined with 24-hour ABPM.And then the blood pressure control and the nursing total satisfaction of the two groups were compared.Results There was no significant difference in systolic blood pressure(SBP) and diastolic blood pressure (DBP) between the two groups before intervention (P＞0.05).The SBP and the DBP after intervention 1,3 months were lower than before between the two groups (P<0.05).There was no significant difference in SBP and DBP between the two groups after 1 month of intervention (P＞0.05).After 3 months of intervention,the SBP,DBP in the experimental group were lower than those in the control group,and the differences were statistically significant (P<0.05).The total nursing satisfaction of the experimental group was higher than that of the control group,and the difference was statistically significant (P<0.05).Conclusion Continuous nursing combined with 24-hour ambulatory blood pressure monitoring intervention in patients with essential hypertension can not only improve the nursing satisfaction of patients,but also effectively control their blood pressure level,which is worthy of clinical application. 2020 Vol. 27 (14): 234-236转240 [Abstract] ( 66 ) HTML (32 KB)  PDF  (0 KB)  ( 10 ) 237 Application of psychological intervention based on Wechat platform in young patients with acute myocardial infarction YANG Xue-hui Objective To study the application effect of psychological intervention based on Wechat platform in young patients with acute myocardial infarction acute myocardial infarction (AMI).Methods Seventy-six young patients with AMI treated in our hospital from June 2017 to March 2018 were selected as the research subjects.The patients were divided into an experimental group (n=38) and a control group (n=38) using a random number table.Patients in the control group were given routine psychological intervention,，and in the experimental group,psychological intervention based on Wechat platform was used.The patients were followed up for 12 months after discharge.The compliance,negative emotional changes,and quality of life of the two groups between 6 and 12 months after discharge were compared.Results The compliance with medication,lifestyle,regular follow-up,and control of risk factors 12 months after discharge from the hospital were higher than that of the control group,and the differences were statistically significant(P<0.05).The Hamilton depression scale (HAMD) and Hamilton anxiety scale (HAMA) scores of the experimental group after intervention were lower than those of the control group,the vitality,social function,health status and overall health scores were higher than those of the control group,and the differences were statistically significant (P<0.05).Conclusion The psychological intervention based on Wechat platform is ideally applied to young patients with AMI.It can significantly improve the compliance of patients with medical treatment,improve the depression and anxiety of patients,and enhance the quality of life of patients. 2020 Vol. 27 (14): 237-238 [Abstract] ( 63 ) HTML (32 KB)  PDF  (0 KB)  ( 9 ) 241 Application of ″empathic″ nursing model in psychological nursing of acute myocardial infarction QIU Wen-qian Objective To explore the application of ″empathic″ nursing mode in psychological nursing of acute myocardial infarction (AMI).Methods From April 2017 to August 2018,98 patients with AMI treated in our hospital were selected and divided into observation group and control group according to random number table method,49 cases in each group.The patients in the control group underwent routine psychological nursing intervention.The observation group implemented the ″empathic″ nursing model on the basis of the control group.After the nursing,the psychological and emotional changes and hospitalization time of two groups were compared.Results After the nursing,the scores of self-rating depression scale (SDS) and self-rating anxiety scale (SAS) in the observation group were lower than those in the control group (P<0.05).The length of stay was (7.8±5.9) d in the observation group and (15.9±3.5) d in the control group.The length of stay in the observation group was shorter than that in the control group,the difference was statistically significant (P<0.05).The nursing total satisfaction of the observation group was 100.0%,higher than that of the control group (89.8%),and the difference was statistically significant (P<0.05).Conclusion The ″empathic″ nursing model has a significant application value in the psychological nursing of AMI,which can effectively improve the patient′s psychological and emotional state,maintain the patient′s emotional stability,thereby stabilizing the condition and shortening the hospitalization time of the patient.It is recommended to clinical promotion. 2020 Vol. 27 (14): 241-243 [Abstract] ( 66 ) HTML (32 KB)  PDF  (0 KB)  ( 5 ) 244 Application effect of psychological nursing in obstetric midwifery promoting natural delivery MENG Qing-na Objective To explore the application effect of psychological nursing in obstetrical midwifery to promote natural delivery.Methods A total of 120 pregnant women admitted to our hospital from February 2018 to April 2019 were selected as subjects.They were divided into group A and group B according to the method of drawing lots,60 cases in each group.Group A was treated with routine obstetrical midwifery intervention combined with psychological nursing intervention,and group B was treated with routine obstetrical midwifery intervention.The time of labor,the amount of delivery blood loss,the occurrence of adverse pregnancy outcome,nursing satisfaction score,mental health score,pain score,neonatal Apgar score and quality of life score were compared between the two groups.Results In group A,the time of labor was shorter than that of group B,the differences were statistically significant (P<0.05).The amount of blood loss in group A was (352.32±31.13) ml,which was less than that of group B of (389.52±32.22) ml,and the difference was statistically significant (P<0.05).The total incidence of adverse pregnancy outcome in group A was 1.67%,which was lower than 18.33% in group B,the difference was statistically significant (P<0.05).The scores of the mental health of group A and the scores of pain were lower than those of group B,the differences were statistically significant (P<0.05).The scores of Apgar,quality of life and the nursing satisfaction in group A were higher than those of group B,the differences were statistically significant (P<0.05).Conclusion The effect of psychological nursing in obstetrical delivery is remarkable,which can effectively shorten the labor process,improve the psychological state,maternal and infant outcome,pain degree.It is well recognized and can be popularized in clinical practice. 2020 Vol. 27 (14): 244-246 [Abstract] ( 55 ) HTML (31 KB)  PDF  (0 KB)  ( 6 ) 247 Application of high-quality nursing after cesarean section for primipara YU Hai-yan Objective To discuss the application of high-quality nursing after cesarean section for primipara.Methods A total of 126 parturients admitted to our hospital from January 2018 to April 2019 were selected as the research subjects,they were divided into observation group (n=62) and control group (n=64) according to different nursing methods.Parturients in control group were given routine nursing program,while parturients in observation group were given high-quality nursing intervention on the basis of routine nursing.The breast-feeding skills score,lactation volume,breast-feeding situation and total maternal satisfaction were compared between the two groups.Results The breastfeeding skills score and breast feeding rate in observation group were higher than those in control group,the differences were significant (P＜0.05）.The lactation volume in observation group was higher than that in control group,the difference was statistically significant (P<0.05).The total nursing satisfaction in observation group was higher than that in control group,the difference was significant (P<0.05).Conclusion High-quality nursing can improve primipara breastfeeding skills and breast-feeding rate,and help improve women′s satisfaction. 2020 Vol. 27 (14): 247-249 [Abstract] ( 69 ) HTML (31 KB)  PDF  (0 KB)  ( 13 ) 250 Effect of bedside examination and interactive health education on discharging compliance behavior of patients with double J tube HE Jie-ye； FENG Lu-lu； LI Jie-ting Objective To explore the effect of bedside examination interactive health education on the behavior of patients with double J tubes discharged from hospital following doctor′s advice.Methods A total of 122 patients with indwelling double J tubes admitted to our hospital from December 2016 to December 2018 were selected as research objects,and divided into conventional group and observation group according to the single number and double number of inpatient room.The single number was 60 cases in conventional group,and the double number was 62 cases in observation group.The control group was given conventional health education,while the observation group was given bedside examination interactive health education.The two groups of patients were compared in terms of their knowledge,selfmanagement ability,compliance with doctor′s advice and patient satisfaction.Results The patients in the observation group had a higher degree of knowledge and self-management ability,and the patients′ compliance with doctor′s advice and satisfaction than those in the control group,with statistical differences (P<0.05).Conclusion Bedside examination interactive health education can effectively improve the awareness and self-management ability of patients with indwelling double J tubes to health education mode,make patients consciously abide by doctor′s advice,promote rehabilitation and improve patients′ satisfaction with medical nursing. 2020 Vol. 27 (14): 250-253 [Abstract] ( 51 ) HTML (33 KB)  PDF  (0 KB)  ( 8 )

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