血府逐瘀胶囊联合阿托伐他汀钙片治疗气滞血瘀型高脂血症的效果

Abstract
Figure/Table
References (20)
Related Citation (14)

Download: PDF (0 KB) HTML (39 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To explore the effect of Xuefu Zhuyu Capsules combined with Atorvastatin Calcium tablets in the treatment of hyperlipidemia of Qi stagnation and blood stasis type.Methods A total of 96 patients with primary hyperlipidemia of Qi stagnation and blood stasis type diagnosed and treated in the department of Neurology clinic of our hospital from January 2017 to November 2019 were selected as the research objects,and they were divided into the control group (48 cases) and the observation group (48 cases) according to the method of random number table methods.Both groups were given diet guidance and lifestyle adjustment.Patients in the control group were given Atorvastatin Calcium tablets orally,The patients in the observation group were given Xuefu Zhuyu Capsules oral capsule on the basis of the treatment in the control group.Both groups were treated for 2 months.The therapeutic effect,the incidence of adverse reactions,the level of blood lipid and the level of traditional Chinese medicine syndrome symptoms before and after treatment of two months were compared between the two groups.Results The total effective rate of the observation group was 95.83%,which was higher than that of the control group (75.00%),the difference was statistically significant(P＜0.05).The levels of total cholesterol (TC),triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) in the two groups after treatment of two months were lower than those before treatment,and the high density lipoprotein cholesterol (HDL-C) level in the observation group after treatment of two months was higher than that before treatment,the difference was statistically significant (P＜0.05).The level of TC,TG and LDL-C in the observation group after treatment of two months were lower than those in the control group,while the level of HDL-C in the observation group after treatment of two months was higher than that in the control group,the difference was statistically significant (P＜0.05).The traditional Chinese medicine symptom scores of the two groups after treatment of two months were lower than before treatment,and the score of traditional Chinese medicine symptoms in the observation group after treatment of two months was lower than that in the control group,the difference was statistically significant (P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups (P＞0.05).Conclusion The treatment of hyperlipidemia patients of Qi stagnation and blood stasis type with Xuefu Zhuyu Capsules combined with Atorvastatin Calcium Tablets can achieve good clinical effect,which can effectively improve the blood lipid index and traditional Chinese medicine symptoms of patients,and does not increase adverse reactions,it is worthy of clinical promotion and application.

Key words： Xuefu Zhuyu Capsules Atorvastatin Calcium Tablets Qi stagnation and blood stasis type Hyperlipidemia

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	LU Feng
	BAI Wei-wei
	LI Li-feng

Cite this article:

LU Feng,BAI Wei-wei,LI Li-feng. Effect of Xuefu Zhuyu Capsules combined with Atorvastatin Calcium Tablets in the treatment of hyperlipidemia of Qi stagnation and blood stasis type[J]. 中国当代医药, 2020, 27(14): 75-78.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I14/75

[2]	宁海珊，刘晓堃，安雪聪，等.他汀类药物在高龄患者中的研究进展[J].中西医结合心血管病电子杂志，2018，6（18）：31-32.
[3]	中国成人血脂异常防治指南修订联合委员会.中国成人血脂异常防治指南（2016年修订版）[J].中华心血管病杂志，2016，44（10）：833-853.
[4]	高秀芳，李勇.《中国成人血脂异常防治指南2016 修订版》更新要点解析[J].中华高血压杂志，2017，25（1）：24-27.
[6]	孙海荣，张澜.浅论他汀药物所致不良反应的特点和预防措施[J].世界最新医学信息文摘，2018，18（47）：95.
[7]	陶红.血府逐瘀胶囊联合丁苯酞治疗缺血性脑血管疾病的临床研究[J].现代药物与临床，2018，33（1）：53-56.
[14]	杨思敏，陈盈，方敏.小剂量阿司匹林辅助治疗在老年冠心病患者颈动脉粥样硬化中的效果[J].中国医药科学，2019，9（6）：60-62.
[1]	葛均波，徐永健，王辰.内科学[M].9版.北京：人民卫生出版社，2018.
[5]	马建林，黄文杰.他汀类药物相关不良反应的研究进展[J].中国医药，2019，14（7）：1118-1120.
[8]	刘卉.血府逐瘀胶囊对阿司匹林抵抗脑梗死患者介入术后血小板聚集和颈动脉狭窄程度的影响[J].中国实用医刊，2018，45（21）：118-121.
[9]	中国中西医结合学会心血管病专业委员会动脉粥样硬化与血脂异常专业组.血脂异常中西医结合诊疗专家共识[J].中国全科医学，2017，20（3）：262-269.
[10]	郑筱萸.中药新药临床研究指导原则（试行）[M].北京：中国医药科技出版社，2002：89.
[11]	余莉.老年心脑血管疾病患者心理问题分析及护理[J].临床医药文献电子杂志，2019，6（12）：114，116.
[12]	沈梦园，牛潇晗，王利新.血脂监测在心脑血管疾病诊疗中的应用[J].中华检验医学杂志，2018，41（11）：893-896.
[13]	于莹，张娴.阿托伐他汀强化治疗对急性脑梗死患者血脂代谢、动脉粥样硬化及炎性因子的影响[J].医学理论与实践，2019，32（11）：1671-1673.
[15]	刘娟，汪和贵，王园，等.PCSK9 与动脉粥样硬化性心血管疾病的新研究进展[J].沈阳医学院学报，2018，20（3）：255-259.
[16]	赵冬.中国人群血脂异常流行趋势和治疗控制现状[J].中华心血管病杂志，2019，47（5）：341-343.
[17]	马里君，何青.新型降脂药物的应用研究进展[J].中华全科医师杂志，2019，18（8）：780-784.
[18]	宁观佳，陈漠水.他汀类药物对高血压患者颈动脉斑块、hs-CRP、LDL-C及HbA1c的影响[J].湖南师范大学学报（医学版），2019，16（4）：102-105.
[19]	宋萍，王贺，司春婴，等.冠状动脉支架内新生动脉粥样硬化的发病机制及化痰活血治疗研究进展[J].山东医药，2019，59（27）：94-97.
[20]	陈光，何浩强，胡坤，等.血府逐瘀胶囊干预气滞血瘀证患者前瞻性多中心随机对照试验[J].中医杂志，2019，60（17）：1476-1482.