参麦注射液辅助治疗对肺尘埃沉着病患者肺部纤维化相关指标的改善作用

Abstract
Figure/Table
References (15)
Related Citation (15)

Download: PDF (0 KB) HTML (33 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the effect of Shenmai Injection on pulmonary fibrosis in patients with pneumoconiosis.Methods A total of 78 patients with pneumoconiosis treated in Hospital of Occupational Disease Prevention and Control in Shaoguan City from March 2017 to March 2019 were selected as the subjects.The patients were divided into experimental group (n=39) and reference group (n=39) by random digital table method.The patients in reference group adopted the routine symptomatic support of spasmolytic,antitussive,expectorant,oxygen-absorbing,anti-inflammatory,fluid infusion and other pneumoconiosis,and the treatment of tetrandrine tablets,and the patients in the experimental group were treated with Shenmai Injection.After treatment,the improvement of pulmonary fibrosis related indexes such as human type Ⅲprocollagen peptide（PⅢP),type Ⅳcollagen (CⅣ) and type Ⅰprocollagen carboxy terminal peptide(PⅠCP) were compared between the two groups,and the clinical efficacy of the two groups was counted.Results Before treatment,there were no significant differences in pulmonary fibrosis indexes such as PⅢP,CⅣand PⅠCP between the two groups (P>0.05).After treatment,the pulmonary fibrosis indexes such as PⅢP,CⅣand PⅠCP in the two groups were lower than those before treatment (P<0.05),and the pulmonary fibrosis indexes such as CⅣand PⅠCP in the experimental group were lower than those in the control group (P<0.05).The total effective rate of treatment in the experimental group was 93.02%,which was higher than that in the control group (74.36%) (P<0.05).Conclusion Shenmai Injection can effectively improve pulmonary fibrosis,delay the development of pneumoconiosis and improve the clinical effect.

Key words： Shenmai Injection Adjuvant therapy Pneumoconiosis Pulmonary fibrosis Therapeutic effect

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	YANG Li-qun
	HUANG Sheng
	DU Ping

Cite this article:

YANG Li-qun,HUANG Sheng,DU Ping. Effect of Shenmai Injection on the improvement of pulmonary fibrosis related indexes in patients with pneumoconiosis[J]. 中国当代医药, 2020, 27(14): 58-60.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I14/58

[1]	孙杰，张碧珠，陈铿铿.2016年某院尘肺病住院患者微生物检测的分析[J].中国城乡企业卫生，2017，26（8）：69-71.
[2]	韩静茵，贾仰民，王淑娟.阿魏酸钠治疗尘肺病肺纤维化的效果及其作用机制的临床研究[J].中国临床药理学与治疗学，2016，21（5）：553-557.
[3]	温玉萍，柳美欣，郝翠英.合理情绪护理干预在改善尘肺患者遵医行为及肺功能中的效果观察[J].山西医药杂志，2017，46（19）：2384-2386.
[4]	樊晶光，王雪涛，王海椒，等.83家井工煤矿在岗农民工尘肺病现状调查及预防对策研究[J].中国安全生产科学技术，2017，13（8）：188-192.
[5]	张璐璐，陈亮，杜丽，等.乌司他丁联合参麦注射液治疗创伤后早期急性肺损伤疗效及对血清TNF-α、IL-6 水平的影响[J].现代生物医学进展，2017，17（33）：150-153，158.
[6]	王东红，杜旭芹.参麦注射液联合西医治疗对尘肺病患者肺部纤维化相关血清指标及抗氧化能力的影响研究[J].世界中西医结合杂志，2016，11（4）：551-554.
[7]	李欣，戴伟荣，李莉，等.尘肺病并发肺气肿患者临床特点分析[J].中华劳动卫生职业病杂志，2017，35（11）：865-867.
[8]	胡强，曹云堡.参麦注射液联合沐舒坦雾化吸入治疗老年COPD 并发肺部感染疗效及对血清sTREM-1、PCT、Leptin的影响[J].现代中西医结合杂志，2018，34（26）：2924-2927.
[9]	李欣，戴伟荣，李莉，等.尘肺病并发肺气肿患者临床特点分析[J].中华劳动卫生职业病杂志，2017，35（11）：865-867.
[10]	刘志勇.益气养阴活血化瘀法治疗肺间质纤维化40例临床观察[J].北京中医药，2017，19（4）：25-27.
[11]	姚晓轶.丹芍化纤胶囊联合西药对尘肺病患者肺纤维化及氧化应激的影响[J].北方药学，2018，15（10）：128-129.
[12]	方柯南.参麦注射液联合利奈唑胺治疗儿童重症肺炎临床疗效及对患者炎性因子的影响[J].陕西中医，2018，22（9）：1187-1190.
[13]	胡晓平，徐洪，杨方.肾素血管紧张素系统调节肽Ac-SDKP在尘肺纤维化中的作用[J].中华劳动卫生职业病杂志，2017，35（35）：720.
[14]	罗晓芳，林丽颖.参麦注射液联合汉防己甲素对尘肺病肺纤维化的疗效[J].深圳中西医结合杂志，2018，28（23）：50-52.
[15]	董明霞，庞波，李茜，等.尘肺患者外周血miR-21 表达与细胞因子分泌、胶原代谢及氧化应激的相关性[J].疑难病杂志，2019，18（2）：147-150.