PM2.5对呼吸系统损伤的研究进展

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Abstract In recent years,environmental pollution and haze weather are increasing with the development of industry and the acceleration of urbanization in China.There are more and more inhalable particles in the atmosphere,and the inhalable particles whose aerodynamic diameter is less than or equal to 2.5 μm (PM2.5) do great harm to human body.The increase of PM2.5 in the environment is positively correlated with the increase of the number of patients with respiratory diseases.PM2.5 has the characteristics of small particle size and large specific surface area.It is easy to carry polycyclic aromatic hydrocarbons and other harmful substances and pathogens.If these substances and bacteria are inhaled into the respiratory tract,they can deposit in the bronchi to promote the release of inflammatory factors and destroy the micro ecological balance of the lung,leading to the occurrence or aggravation of a variety of respiratory system diseases such as pneumonia,bronchial asthma,pulmonary fibrosis,lung cancer and chronic obstructive pulmonary disease.Although some studies have showed the relationship of PM2.5 and respiratory diseases,the research foundation is still relatively weak.This paper reviews the effect of PM2.5 on respiratory diseases and the related mechanisms,so as to provide reference for further research.

Key words： PM2.5 Asthma Pulmonary fibrosis Lung cancer Chronic obstructive pulmonary disease

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	SUN Jing
	ZHANG Mian

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SUN Jing,ZHANG Mian. Research progress of PM2.5 on respiratory system injury[J]. 中国当代医药, 2020, 27(14): 26-29.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I14/26

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