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2020 Vol. 27, No. 8
Published: 2020-03-18
 
 
4 Effect of NGF-BMSCs transplantation on the improvement of symptoms in AD animal model and the levels of apoptosis-related genes Bcl-2and Bax in brain tissue
LIANG Jin; GU Xin-yi; JIANG Zhi-hong; MA Qiang
Objective To investigate the effect of nerve growth factor-bone marrow stromal stem cells (NGF-BMSCs)transplantation on the improvement of symptoms in (AD) animal model and the levels of apoptosis-related genes B lymphocyte tumor-2 (Bcl-2) and Bax in brain tissue.Methods Fifty AD rats were randomly divided into five groups,namely the control group, saline injection group, model group, BMSCs transplantation group and NGF-BMSCs transplantation group, with 10 rats in each group.The behavioral changes of AD rats were observed, and the levels of Bcl-2and Bax in hippocampus of rats were detected.Results The escape latency of the model group and the saline injection group from the first day to the sixth day was shorter than that of the control group, with statistically significant differences (P＜0.05).The escape latency of BMSCs transplantation group and NGF-BMSCs transplantation group from the first day to the sixth day was longer than that of the control group, model group and saline injection group, with statistically significant differences (P＜0.05).The escape latency of the NGF-BMSCs transplantation group from the first day to the sixth day was longer than that of the BMSCs transplantation group, and the difference was statistically significant(P＜0.05).The levels of Bcl-2and Bax in the model group, saline injection group, BMSCs transplantation group, and NGF-BMSCs transplantation group were higher than those in the control group, and the differences were statistically significant (P＜0.05).The Bcl-2levels in the saline injection group and the BMSCs transplantation group were higher than those in the model group, the Bax levels were lower than those in the model group, and the differences were statistically significant (P＜0.05).The levels of Bcl-2in the BMSCs transplantation group and NGF-BMSCs transplantation group were lower than those in the saline injection group, and the differences were statistically significant (P＜0.05).The Bcl-2level in the NGF-BMSCs transplantation group was lower than that in the BMSCs transplantation group, the Bax level was higher than that in the saline injection group and in the BMSCs transplantation group, and the differences were statistically significant (P＜0.05).Conclusion NGF-BMSCs transplantation can inhibit neuronal apoptosis in AD animal models by regulating the expression levels of Bcl-2and Bax in hippocampus.
2020 Vol. 27 (8): 4-7 [Abstract] ( 82 ) HTML (39 KB)  PDF  (0 KB)  ( 5 )
8 Influence of Docetaxel combined with Epirubicin regimen chemotherapy on p53 and vascular endothelial growth factor in patients with triple negative breast cancer
CUI Hai； JIN Yong-min； GAO Ai-hua
Objective To study the effect of Docetaxel combined with Epirubicin regimen chemotherapy in the treatment of triple negative breast cancer (TNBC) and influence on tumor suppressor protein p53 (p53) and vascular endothelial growth factor (VEGF).Methods A total of 124 female TNBC patients admitted to our hospital from January 2013 to December 2015 were selected as the research subjects, and they were divided into experimental group (n=62)and control group (n=62) according to the random number table method.The Control group received Cyclophosphamide combined with Epirubicin regimen chemotherapy, while the experimental group received Docetaxel combined with Epirubicin regimen chemotherapy.The levels of serum VEGF subtypes such as VEGF A, VEGF B, VEGF C and p53 positive expression rates were observed before and after treatment in the two groups.The clinical efficacy, 1 to 3-year survival rates and incidence of toxic and side effect in the two groups of patients were compared.Results After treatment, the levels of VEGF A, VEGF B, and VEGF C in the experimental group were lower than those in the control group, and the differences were statistically significant (P＜0.05).After treatment, the positive expression rate of p53 in the experimental group was lower than that in the control group, and the objective response (OR) rate was higher than that in the control group, the differences were statistically significant (P＜0.05).There were no significant differences in the 1-and 2-year survival rates between the two groups of patients (P＞0.05).The 3-year survival rate in the experimental group was higher than that in the control group, and the difference was statistically significant (P＜0.05).There was no significant difference in the incidence of toxic and side effect between the two groups of patients (P＞0.05).Conclusion Neoadjuvant chemotherapy with Docetaxel and Epirubicin can effectively kill TNBC, and inhibit the expression of VEGF subtypes and p53.The 3-year survival rate is high, the toxic and side effect is less, and it is safe and reliable.
2020 Vol. 27 (8): 8-11转15 [Abstract] ( 81 ) HTML (42 KB)  PDF  (0 KB)  ( 9 )
12 Influencing factors of sentinel lymph node metastasis in stage T1 breast cancer
FU Cheng-bin； LIN Shun-guo； XU Chun-sen； HAN Hui
Objective To explore the influencing factors of sentinel lymph node metastasis in stage T1 breast cancer.Methods The clinical data of 58 patients with stage T1 breast cancer treated in our hospital from January to December 2018 were retrospectively analyzed.All patients underwent sentinel lymph node biopsy.Univariate and multivariate analysis was made on the possible influencing factors including age, tumor size, tumor location, preoperative imaging evaluation, molecular typing, histological grade, Ki67 and lymphovascular invasion.Results Among 58 patients, 11 cases had sentinel lymph node metastasis, the positive rate was 18.97%.Univariate analysis showed that there were statistically significant differences in the positive rates of sentinel lymph nodes under different histological grades, Ki67, and lymphovascular invasion (P＜0.05).Multivariate analysis showed that lymphovascular invasion was an independent risk factor for sentinel lymph node metastasis in T1 stage breast cancer (β=1.792, OR=5.999, 95% CI:1.151-31.269, P=0.033).Conclusion Lymphovascular invasion can predict sentinel lymph node metastasis in stage T1 breast cancer.
2020 Vol. 27 (8): 12-15 [Abstract] ( 100 ) HTML (33 KB)  PDF  (0 KB)  ( 9 )
16 Research progress on the safety of testosterone replacement therapy in patients with prostate cancer
WANG Qi-bo； ZHU Shao-xing
Hypogonadism in men is a clinical syndrome caused by androgen deficiency, for whom testosterone replacement therapy (TRT) is the preferred treatment.However, the use of TRT has been controversial in patients with a previous history of prostate cancer.In recent years, studies on the safety of TRT in patients with prostate cancer at different stages have been reported, including pre-cancerous stage, active surveillance, post-radical treatment and advanced prostate cancer.This article reviews the literatures and the progress in the application safety of TRT in patients with prostate cancer.
2020 Vol. 27 (8): 16-18 [Abstract] ( 76 ) HTML (34 KB)  PDF  (0 KB)  ( 9 )
19
Research progress of intra-operative cell salvage in obstetrics
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Research progress of intra-operative cell salvage in obstetrics #br#[J]. 中国当代医药, 2020,27(8): 19-21转25')" href="#"> HE Xue-yi； LIANG Hai-ying； ZHAO Li-na
Intra-operative cell salvage refers to the collection, storage of the patients′ own blood prior to surgery, or the collection of blood from a patients′ surgery or trauma during surgery and return to the patient.At present, the main concerns of intra-operative cell salvage in cesarean section are hemolytic diseases caused by amniotic fluid embolism and fetal red blood cell transfusion, and also include problems such as assessment of red blood cell quality, coagulation dysfunction and leukocyte filtration.Under the premise of correctly grasping the indications and standardizing the operation, intra-operative cell salvage during cesarean section is safe and effective, which can effectively reduce the amount of allogeneic blood transfusion during surgery.
2020 Vol. 27 (8): 19-21转25 [Abstract] ( 83 ) HTML (36 KB)  PDF  (0 KB)  ( 9 )
22 Research progress of self-management skill training combined with music therapy in promoting the rehabilitation of schizophrenics
LU Shen-yan； MO Li-li； LIAO Hai-cen； YANG Dai-lan
Schizophrenia is a serious chronic disease in psychiatry.It is a kind of serious mental disease commonly seen in clinic.At present, it is mainly treated by antipsychotics, which can not be cured.It has a high recurrence rate and disability rate.This paper introduces the related concepts of self-management skill training and music therapy, the importance of carrying out, the research status at home and abroad, the contents and methods of implementation, the main objects and time of intervention, reviews the application of self-management skills training and music therapy in schizophrenic patients and the effect of intervention, so as to provide an effective theoretical basis for further improving self-management skills training combined with music therapy to promote the rehabilitation of schizophrenics.
2020 Vol. 27 (8): 22-25 [Abstract] ( 76 ) HTML (38 KB)  PDF  (0 KB)  ( 10 )
26 Analysis of risk factors for the occurrence of capillary leak syndrome in patients with sepsis
YANG Wen-tao； LIN Leng； CHEN Ning
Objective To study the risk factors for the occurrence of capillary leak syndrome in patients with sepsis.Methods A total of 100 patients with sepsis treated in our hospital from October 2017 to September 2018 were selected as the subjects.According to whether suffering from the complication of capillary leak syndrome, the patients were divided into the leakage group (n=13, with the complication of capillary leak syndrome) and non-leakage group (n=87,without complication of capillary leak syndrome).The clinical data of the two groups were compared and analyzed.The risk factors of capillary leak syndrome in patients with sepsis were also analyzed.Results For patients in the leakage group, the levels of procalcitonin (PCT), C-reactive protein (CRP), angiopoietin-2 (Ang2), angiopoietin receptor 2 antibody (Tie2), fasting blood glucose and lactic acid, and the score of sepsis-related organ failure assessment (SOFA) were higher than those of the non-leakage group, and the angiopoietin-1 (Ang1) level was lower than that of the non-leakage group, the incidence of coagulation disorders and multiple organ dysfunction syndrome (MODS) involved with three organs or more was higher than that of non-leakage group, and the state of sepsis was more serious than that of the non-leakage group, the differences were statistically significant (P＜0.05).Logistic multivariate analysis showed that the level of Ang1 decreased (β=0.363, OR=1.247, 95%CI [1.121, 1.697]), the levels of Ang2 (β=0.964, OR=1.356, 95%CI[1.135, 1.896]) and Tie2 receptor increased [β=0.891, OR=1.289, 95%CI [1.127, 1.731]), high lactic acid level (β=0.569, OR=1.256, 95%CI [1.112, 1.863]), high SOFA score (β=0.921, OR=1.264, 95%CI [1.125, 1.896]), the state of sepsis was severe [β=0.634, OR=1.446, 95%CI [1.141,1.934]), the organs involved by MODS was three or more(β=0.697, OR=1.446, 95%CI [1.256, 1.943]) were risk factors for the occurrence of capillary leak syndrome in patients with sepsis (P＜0.05).Conclusion The decreased Ang1 level, and elevated Ang2 and Tie2 receptor levels, high level of serum lactate, high score of SOFA, severe sepsis, three or more organs involved by MODS are all the risk factor for the occurrence of capillary leak syndrome in patients with sepsis.
2020 Vol. 27 (8): 26-28转36 [Abstract] ( 90 ) HTML (32 KB)  PDF  (0 KB)  ( 13 )
29 Comparison the clinical effect of laparoscopic appendectomy and open appendectomy in the treatment of acute appendicitis
LIU Dian-hua； LIU Yong-ling； LIU Yi-ming
Objective To compare the clinical effect of laparoscopic appendectomy and open appendectomy in the treatment of acute appendicitis.Methods A total of 100 patients with acute appendicitis in our hospital from February 2017 to February 2018 were selected as the study objects, they were divided into observation group (50 cases) and control group (50 cases) according to the random number table method.The observation group was treated with laparoscopic appendectomy, the control group was treated with open appendectomy.Surgical indicators, visual analog scale (VAS) scores before and after surgery, and total complication rate were compared between the two groups.Results The operation time, anal exhaust time and hospitalization time of the observation group were shorter than those of the control group, the amount of bleeding was less than that of the control group, the differences were statistically significant (P＜0.05).There was no significant difference in VAS score before surgery between the two groups (P＞0.05).The VAS scores in the observation group at 6, 12, and 24 hours after surgery were lower than those in the control group, the differences were statistically significant (P＜0.05).The total incidence of complications in the observation group was lower than that in the control group, the difference was statistically significant (P ＜0.05).Conclusion Laparoscopic appendectomy is applied to acute appendicitis, which can shorten the operation time, anal exhaust time and hospitalization time, reduce the amount of bleeding, relieve the patient′s postoperative pain, and reduce the incidence of complications.
2020 Vol. 27 (8): 29-31转44 [Abstract] ( 90 ) HTML (34 KB)  PDF  (0 KB)  ( 13 )
32 Analysis of influencing factors on blood coagulation composite indexes of maternal thromboelastography
LIU Xiao-hua； LYU Zhi-ying； OUYANG Lin； ZHANG Zi-hui； LI Yun； ZHANG Ren-xiu
Objective To investigate the parameters of thromboelastic of pregnant women in different pregnancy periods and analyze the influencing factors of postpartum hemorrhage.Methods From January 2018 to February 2019, 128 pregnant women admitted to our hospital were selected as the pregnancy group.All the pregnant women had no pregnancy complications.Based on whether they had postpartum hemorrhage during delivery, pregnant women in the pregnancy group were divided into two groups, namely, the group without postpartum hemorrhage (90 cases) and the group with postpartum hemorrhage (38 cases).Moreover, 90 cases of pregnant women with different pregnancies who came to our hospital for pregnancy examination at the same time were selected for the study.According to their different gestational ages, they were divided into the early pregnancy group (n=30), the middle pregnancy group (n=30), and the late pregnancy group (n=30).Thirty non-pregnant healthy physical who came to our hospital at the same time for physical examination of antagonism were selected as the non-pregnant group.The related parameters of thromboelastogram, and the reference value of coagulation composite index of thromboelastogram in postpartum hemorrhage were tested.The coagulation function, thromboelastogram index were observed.The related factors affecting patients′ bleeding were analyzed and risk of each independent factor was performed with multi-factor regression analysis.Results In the pregnancy group, the thromboelastography indexes of the clotting time during the initial clotting phase (R value) and clot formation rate (K value) were lower than those in the non-pregnancy group, with statistically significant differences (P＜0.05).The thromboelastography indexes of fibrinogen function (Angle), platelet function (MA value) and comprehensive hemolysis index (CI value) of the pregnancy group were higher than those of the non-pregnancy group, with statistically significant differences (P＜0.05).The thromboelastography indexes of R value and K value in the late pregnancy group were lower than those in the middle pregnancy group and the early pregnancy group, and the differences were statistically significant (P＜0.05).The thromboelastography indexes of Angle, MA value and CI value in the late pregnancy group were higher than those in the middle pregnancy group and the early pregnancy group,with statistically significant differences (P＜0.05).The thromboelastography indexes of R value and K value in the middle pregnancy group were lower than those in the early pregnancy group, with statistically significant differences (P＜0.05).The thromboelastography indexes of Angle, MA value and CI value in the middle pregnancy group were higher than those in the early pregnancy group, with statistically significant differences (P＜0.05).The results of univariate analysis suggested that the thromboelastography indexes of R value and K value postpartum hemorrhage group were higher than those of the non-postpartum hemorrhage group, with statistically significant differences (P ＜0.05).The thromboelastography indexes of Angle and CI value in postpartum hemorrhage group were lower than those in the control group, with statistically significant differences (P＜0.05).The results of Logistic multivariate regression analysis suggested that the influencing factors for postpartum hemorrhage included the thromboelastography indexes of the R value(β=2.015, OR=13.853, 95% CI: 8.876-15.243), K value (β=1.304, OR=8.475, 95% CI: 6.765-10.974), Angle (β=0.742,OR=10.075, 95% CI: 7.391-12.341) and the CI value (β=1.839, OR=10.097, 95% CI: 8.492-13.473), the differences were statistically significant (P＜0.05).Conclusion According to the analysis of clinical data, there are significant differences in R value, K value, Angle, and CI value in the coagulation composite index of thromboelastogram for postpartum hemorrhage women compared with those without postpartum hemorrhage.The R value, K value, Angle, and CI value are influencing factors of postpartum hemorrhage.
2020 Vol. 27 (8): 32-36 [Abstract] ( 95 ) HTML (45 KB)  PDF  (0 KB)  ( 12 )
37 Application effect of community comprehensive rehabilitation intervention on patients with chronic obstructive pulmonary diseases at a stable stage
GUO Xing-hua； ZHANG Wei-qing； LIU Yong ； HE Yong-long； LI Yun-wei； LIU Wei-rong
Objective To explore the application effect of community comprehensive rehabilitation intervention on patients with chronic obstructive pulmonary diseases (COPD) at a stable stage.Methods A total of 84 patients with stable COPD admitted to our hospital from January 2017 to January 2018 were enrolled as subjects.They were divided into observation group and control group by random number table method, 42 cases in each group.In the control group, the patients received routine outpatient rehabilitation.In the observation group, the patients received face-to-face or telephone follow-up for community comprehensive rehabilitation, including health education, persuasion to quit smoking,oxygen therapy intervention, respiratory training, nutritional support, psychological intervention, symptom recognition and medicinal guidance.The hospitalization rate, lung function index and quality of life score were all compared between the two groups after 12 months.Results After the intervention, the rehospitalization rate of the observation group was lower than that of the control group with a statistical difference (P＜0.01).There were no significant differences in the terms of first-second forced expiratory volume (FEV1), percentage of FEV1 in forced vital capacity (FVC) (FEV1/FVC) and peak expiratory flow (PEF) between the two groups before intervention (P＞0.05).After intervention, the levels of the FVC, FEV1, PEF indicators in the observation group were higher than those of the control group, the differences were statistically significant (P＜0.01).There were no significant differences in the scores of life quality, such as ability of daily life, ability of social activities, psychological state of depression and psychological state of anxiety between the two groups before intervention (P＞0.05).The scores of life quality, such as ability of daily life, ability of social activities, psychological state of depression and psychological state of anxiety in the observation group were lower than those of the control group, the differences were statistically significant (P＜0.01).Conclusion Community comprehensive rehabilitation intervention can reduce the rehospitalization rate, and improve the lung function and the quality of life of patients, which is worth promoting.
2020 Vol. 27 (8): 37-40 [Abstract] ( 81 ) HTML (40 KB)  PDF  (0 KB)  ( 11 )
41 Application effect of Carbazochrome Tables combined with Tranexamic Acid Sodium Chloride Injection on hemoptysis patients
OUYANG Zhi-cheng; LIU Xue-wen
Objective To explore application effect of Carbazochrome Tables combined with Tranexamic Acid Sodium Chloride Injection on hemoptysis patients.Methods A total of 70 hemoptysis patients who were admitted to the Department of Respiratory Medicine, Pingxiang People′s Hospital, during the period from January 2016 to December 2018 were selected as subjects.They were divided into control group and experimental group by random number table method, 35 cases in each group.The control group was treated with Carbazochrome Tables, while experimental group was treated with Carbazochrome Tables combined with Tranexamic Acid Sodium Chloride Injection.The clinical curative effect of the two groups was statistically analyzed.The daily hemoptysis volume and stop time of hemoptysis before and after treatment were compared between the two groups.The coagulation function related indexes such as prothrombin time (PT), thrombin time (TT), activated partial thromboplastin time (APTT) and fibrinogen (Fbg) were compared between the two groups.The incidence of adverse reactions during treatment was compared between the two groups.Results The total effective rate was 91.43% in the experimental group, higher than 71.43% in the control group, with statistically significant differences (P＜0.05).The daily hemoptysis volume of the experimental group after treatment was less than that of the control group, and the hemoptysis cessation time was shorter than that of the control group, the differences were statistically significant (P＜0.05).After treatment, PT in the experimental group was longer than the control group, the TT, APTT were shorter than those in the control group, and Fbg level was lower than the control group, with statistically significant differences (P＜0.05).The total incidence of adverse reactions was 8.57% in the experimental group and 20.00% in the control group.There was no statistically significant difference in the total incidence of adverse reactions between the two groups (P＞0.05).Conclusion The curative effect of Carbazochrome Tables combined with Tranexamic Acid Sodium Chloride Injection is significant on hemoptysis, which can reduce daily hemoptysis volume, shorten stop time of hemoptysis, and improve coagulation function.
2020 Vol. 27 (8): 41-44 [Abstract] ( 72 ) HTML (36 KB)  PDF  (0 KB)  ( 11 )
45 Effect comparison of microsurgical operation and flaps free replantation in the treatment of retrograde avulsion of hand skin
YUAN Yong
Objective To explore the clinical effect of microsurgical operation and flaps free replantation in the treatment of retrograde avulsion of hand skin.Methods A total of 80 cases with retrograde avulsion of hand skin in our hospital from October 2015 to October 2017 were selected as subjects.According to the random number table method,they were divided into the control group (n=39) and the observation group (n=41).The control group received flaps free replantation treatment, patients in the observation group received microsurgical operation.The survival of hand skin,hand function and the total incidence of adverse reactions were compared between the two groups.Results The total effective rate of hand skin survival in the observation group was 85.4%, which was higher than that in the control group(64.1%), the difference was statistically significant (P＜0.05).The excellent rate of hand function score of the observation group was 90.2%, which was higher than that of the control group with 66.7%, the difference was statistically significant (P ＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups, which was comparable (P＞0.05).Conclusion Microsurgical treatment of avulsion injury of hand skin has good clinical effect.The skin survival rate of hand is high, hand function is good, and there is no obvious adverse reaction.It is safe and reliable, and is worthy of clinical application.
2020 Vol. 27 (8): 45-47 [Abstract] ( 71 ) HTML (32 KB)  PDF  (0 KB)  ( 14 )
48 Predictive value of combined detection of albumin, cystatin C and bilirubin in acute cerebral infarction complicated with acute kidney injury
CHI Rui-feng； LIN Bing-wei； LIN Xi-chun
Objective To investigate the predictive value of combined detection of albumin (ALB), cystatin C (CysC)and bilirubin (TB) in acute cerebral infarction complicated with acute kidney injury (AKI).Methods A total of 30 patients with acute cerebral infarction and AKI admitted to our hospital from January to December 2018 were selected as the acute cerebral infarction+AKI group, 30 patients with acute cerebral infarction without AKI were selected as the acute cerebral infarction group, and another 30 healthy subjects with healthy physical examinations were selected as the controls group.The serum biochemical indicators and the national institutes of health stroke scale (NIHSS) scores were compared among each group of subjects.Logistic regression analysis was performed on the indicators with differences,and the receiver operating characteristic (ROC) curve was used to evaluate the predictive value of the indicators.Results The levels of ALB, CysC, and high-sensitivity C-reactive protein (hs-CRP) in the acute cerebral infarction+AKI group were higher than those in the acute cerebral infarction group and control group, the TB level was lower than that in the acute cerebral infarction group and control group, the NIHSS score in the acute cerebral infarction+AKI group was higher than that in the acute cerebral infarction group, and the differences were statistically significant (P＜0.05).Multivariate Logistic regression analysis showed that ALB, CysC, and TB were risk factors for acute cerebral infarction with AKI (P＜0.05).ROC curve analysis showed that the area under the curve (AUC) of the combined detection of ALB,CysC, and TB was larger than that of ALB, CysC, and TB detection alone, and the differences were statistically significant (P＜0.05).Conclusion ALB, CysC and TB have high predictive value for acute cerebral infarction complicated with AKI, and combined detection can improve prediction sensitivity and specificity.
2020 Vol. 27 (8): 48-50转55 [Abstract] ( 85 ) HTML (34 KB)  PDF  (0 KB)  ( 12 )
51 Effect of minimally invasive puncture drainage combined with craniotomy hematoma evacuation in the treatment of patients with hypertensive cerebral hemorrhage and cerebral hernia
ZHANG Yong-an; XU Jian-ping; CHEN Xu; GONG Shao-hui; YU Bin; XIONG Cheng-ying; ZHAN Jian
Objective To explore clinical effect of minimally invasive puncture drainage combined with craniotomy hematoma evacuation in the treatment of patients with hypertensive cerebral hemorrhage and cerebral hernia.Methods A total of 214 patients with hypertensive cerebral hemorrhage and cerebral hernia treated in our hospital from March 2013 to September 2017 were selected as the research subjects.They were divided into the control group (103 cases)and the observation group (111 cases) according to different surgical methods.The patients in control group underwent craniotomy hematoma evacuation, while patients in observation group underwent minimally invasive puncture drainage combined with craniotomy hematoma evacuation.The time of relieving brain tissue pressure, postoperative awake time,hospitalization time and incidence of postoperative complications in both groups were recorded.The treatment effect was compared between the two groups.At 6 months after surgery, Glasgow outcome scale (GOS) was applied to evaluate prognosis, and the quality of life was evaluated by the MOS item short from health survey (SF-36).Results The total effective rate of treatment in the observation group was 89.19%, which was higher than 77.67% in the control group,and the difference was statistically significant (P＜0.05).The time of relieving brain tissue pressure and hospitalization time in the observation group were shorter than those in the control group, with statistically significant differences (P＜0.05).The postoperative awake time in the observation group was shorter than that in the control group, and the difference was statistically significant (P＜0.05).The total incidence rate of postoperative complications in the observation group was 15.32%, which was lower than 28.16% in the control group, and the difference was statistically significant(P ＜0.05).The prognosis of the observation group was better than that of the control group, and the difference was statistically significant (P＜0.05).The quality of life scores of patients in the observation group at 6 months after surgery were higher than those in the control group, and the differences were statistically significant (P＜0.05).Conclusion The effect of minimally invasive puncture drainage combined with craniotomy hematoma evacuation is good in patients with hypertensive cerebral hemorrhage combined with cerebral hernia, which can effectively improve their prognosis, and increase quality of life.
2020 Vol. 27 (8): 51-55 [Abstract] ( 91 ) HTML (62 KB)  PDF  (0 KB)  ( 7 )
56 Effect of electric stimulation on dysphagia after stroke
SONG Qin-qin； LUO Zi-rui
Objective To investigate the effect of electric stimulation on dysphagia after stroke (CVA).Methods Fifty patients with post-CVA dysphagia admitted to our hospital from January to June 2018 were enrolled.According to the serial number assigned during the patient consultation, the odd-number group method was used to divide into observation group and control group, 25 cases in each group.The control group was given routine rehabilitation training.The observation group was treated with electrical stimulation on the basis of rehabilitation training.After one course of treatment (20 days), the treatment effect and complications were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group, and the complication rate was lower than that of the control group.The differences were statistically significant (P＜0.05).Conclusion Electric stimulation is effective in the treatment of dysphagia after CVA, which can effectively improve the dysphagia caused by CVA and reduce the probability of complications.Therefore, it is worthy to be selected by hospitals at all levels according to the actual situation of patients.
2020 Vol. 27 (8): 56-58 [Abstract] ( 85 ) HTML (30 KB)  PDF  (0 KB)  ( 11 )
59 Effect comparison of Venlafaxine and Sertraline in the treatment of senile depression
TIAN Ge
Objective To compare the clinical effect of Venlafaxine and Sertraline in the treatment of senile depression,and to evaluate the influence on patients′ cognitive function, so as to provide reference for clinical rational use of drugs.Methods Eighty elderly patients with depression admitted to Kangning Hospital for Demobilized Soldiers in Liaoning Province from August 2017 to April 2019 were selected as the study subjects.They were divided into divided into control group and experimental group according to the random number table method, with 40 cases in each group.The control group was treated with Sertraline, and the experimental group was treated with Venlafaxine.The clinical efficacy and cognitive function of the two groups were compared.Results There was no significant difference in the total effective rate between the experimental group and the control group (90.00% vs.87.50%) (P＞0.05).There was no significant difference between the two groups in the indexes of Wisconsin card sorting test (WCST) before treatment (P＞0.05).After treatment, the total response number, persistent error number and non-persistent error of the two groups were lower than that before treatment, and the correct response number and complete classification number were higher than those before treatment, the differences were statistically significant (P＜0.05).The total response number, persistent error number and non-persistent error number of the experimental group were lower than those of the control group,and the correct response number and complete classification number of the experimental group were higher than those of the control group, the differences were statistically significant (P＜0.05).Conclusion For the elderly patients with depression, clinical use of Venlafaxine and Sertraline can achieve better clinical efficacy, and can effectively improve the depressive symptoms of patients, but the former venlafaxine is more conducive to promoting the recovery of cognitive function of patients, it is worth learning.
2020 Vol. 27 (8): 59-61转65 [Abstract] ( 125 ) HTML (32 KB)  PDF  (0 KB)  ( 13 )
62 Effect of green channel construction on clinical treatment of stroke patients in secondary hospital
HUANG Jun-jie； HUANG Wei-xiong
Objective To explore the effect of green channel construction on clinical treatment of stroke patients in secondary hospital.Methods A total of 56 stroke patients treated in our hospital from January 2018 to February 2019 were selected as the subjects, and divided into reference group and analysis group by random number table method,with 28 cases in each group.The reference group was treated with routine treatment, and the analysis group was treated with the green channel for stroke in the secondary hospital.The pain, neurological deficit, activity, motor function and quality of life of the two groups were compared.The recovery of the two groups was observed, and the treatment cost of the patients was counted.Results The visual analogue scale (VAS) score and neurological deficit scale (NIHSS) score in the analysis group were lower than those in the reference group, the difference were statistically significant (P＜0.05).The life activity scale (Barthel index), motor function scale (FMA) and quality of life scale (QOL) scores in the analysis group were higher than those in the reference group, while the scores of living ability (mRS) and the cost of treatment were lower than those in the reference group, the difference were statistically significant (P＜0.05).Conclusion For the treatment of stroke patients, the construction of stroke green channel in secondary hospital is effective, and this scheme is worth applying.
2020 Vol. 27 (8): 62-65 [Abstract] ( 80 ) HTML (35 KB)  PDF  (0 KB)  ( 8 )
66 Observation on antineoplastic therapy-related hypertension with Apatinib
ZHOU Jun; XU Hai-ling; HUA Min; ZHOU Yuan-feng; PING Xiang-hua
Objective To investigate the clinical effect of Apatinib in the treatment of advanced malignant tumors and its effect on blood pressure.Methods Forty-two patients with advanced malignant tumors admitted to our hospital from January 1, 2016 to December 31, 2017 were enrolled in the study.They were divided into two groups according to random sampling, 21 cases each group.The control group received placebo and nutritional support treatment.The observation group was treated with Apatinib on the basis of the control group, and the total effective rate, adverse reactions,and grade of hypertension were observed and evaluated.Results The total effective rate of the observation group was higher than that of the control group (P＜0.05).The total incidence of adverse reactions in the observation group was higher than that in the control group, the difference was statistically significant (P＜0.05).The total incidence of hypertension in the observation group was higher than that in the control group, and the difference was statistically significant (P＜0.05).There was no significant difference in the grade of hypertension between the two groups (P＞0.05).Conclusion Apatinib has high clinical value in patients with advanced malignant tumors, which is beneficial to prolonging survival.However, the clinical incidence of hypertension is high, and the mechanism of blood pressure elevation needs further discussion.
2020 Vol. 27 (8): 66-68 [Abstract] ( 90 ) HTML (31 KB)  PDF  (0 KB)  ( 12 )
69 Application of vacuum-assisted mammotomy in biopsy screening of suspected breast cancer
WU Hao; LIU De-jian; WANG Jing-pei; HUANG Yan; GAN Yu; ZHANG Shao-wei
Objective To explore the application of vacuum-assisted rotational breast biopsy (VABB) in screening suspicious breast cancer patients.Methods A total of 207 patients with breast tumors treated in our hospital from November 2017 to February 2018 was selected as the research objects.According to the method of voluntary grouping, the patients were divided into study group (106 cases) and control group (101 cases).The study group was given VABB biopsy and the control group was given open surgery biopsy.The incision length, operation time, bleeding volume, bandaging experience, complications, postoperative satisfaction, breast conserving rate and follow-up results were compared between the two groups.Results The incision length and operation time of the study group were shorter than those of the control group, the amount of bleeding was less than that of the control group, and the satisfaction score was higher than that of the control group, the differences were statistically significant (P＜0.05).There was no significant difference in bandaging experience score between the two groups (P＞0.05).There was no significant difference in malignancy,lymphatic positive and breast-conserving rate between the two groups (P＞0.05).Conclusion VABB has the advantages of minimally invasive, aesthetic, puncture biopsy and excision of multiple tumors at one time.It can be standardized in the screening of suspected breast cancer tumors.The treatment of breast cancer deserves further study.
2020 Vol. 27 (8): 69-72 [Abstract] ( 79 ) HTML (37 KB)  PDF  (0 KB)  ( 13 )
73 Expression of metadherin and vascular endothelial growth factor in epithelial ovarian cancer and its relationship with clinical features of epithelial ovarian cancer
ZHENG Wen-ling； HUANG Xiao-ling
Objective To investigate the expression of metadherin (MTDH) and vascular endothelial growth factor(VEGF) in epithelial ovarian cancer and its association with the clinicopathological features of epithelial ovarian cancer.Methods Forty patients with epithelial ovarian cancer who were admitted to our hospital from February 2017 to January 2019 were enrolled as study group, 20 patients with benign epithelial ovarian cancer were enrolled in the routine group,and 20 healthy people were selected as healthy comparison group.The expressions of MTDH, VEGF mRNA and protein in ovarian epithelial tissues of each group were examined by reverse transcription-polymerase chain reaction (RT-PCR)and immunohistochemical SP method.Results The expressions of MTDH mRNA, VEGF mRNA and the positive expression rates of MTDH and VEGF in patients with different International Federation of Gynecology and Obstetrics (FIGO) stage epithelial ovarian cancer were significantly different (P＜0.05).MTDH mRNA and VEGF mRNA in patients with epithelial ovarian cancer with different lymph node spread, there were no significant differences in mRNA expression and positive expression rates of MTDH and VEGF (P＞0.05), and there was a positive correlation between the expression of MTDH and VEGF in epithelial ovarian cancer（P＜0.05）.Conclusion There is a close relationship between VEGF and MTDH and the occurrence and deterioration of epithelial ovarian cancer.
2020 Vol. 27 (8): 73-75转79 [Abstract] ( 91 ) HTML (32 KB)  PDF  (0 KB)  ( 7 )
76 Clinical effect of Oxaliplatin combined with chemotherapy for colorectal cancer
WU Hai-bo
Objective To investigate the clinical effect of Oxaliplatin combined with chemotherapy in the treatment of colorectal cancer.Methods A total of 120 patients with colorectal cancer admitted in our hospital from April 2018 to April 2019 were selected as subjects, and they were divided into the study group (n=78) and the control group (n=42).The patients in the control group were treated with chemotherapy and patients in the study group were treated with chemotherapy combined with Oxaliplatin.The treatment effect, adverse reactions, tumor necrosis factor-α (TNF-α), and interleukin-2 (IL-2) levels were compared between the two groups.Results The total effective rate of patients in the study group was higher than that in the control group, and the difference was statistically significant (P＜0.05).The total incidence of adverse reactions in the study group was lower than that in the control group, and the difference was statistically significant (P＜0.05).Before treatment, there was no significant difference in TNF-α and IL-2between the two groups (P＞0.05).After treatment, the TNF-α levels in both groups were lower than before treatment, and IL-2levels in both groups were higher than those before treatment, and the differences were statistically significant (P＜0.05).After treatment, TNF-α in the study group was lower than that in the control group, and IL-2was higher than that in the control group, with statistically significant differences (P＜0.05).Conclusion The combined application of Oxaliplatin and chemotherapy in the treatment of colorectal cancer can obviously improve the therapeutic effect and reduce the incidence of adverse reactions, which is worthy of application and promotion in various hospitals.
2020 Vol. 27 (8): 76-79 [Abstract] ( 84 ) HTML (39 KB)  PDF  (0 KB)  ( 6 )
80 Effect of thoracoscopic radical resection of lung cancer in the treatment of elderly patients with non-small cell lung cancer and related factors of postoperative survival rate
FENG Yong
Objective To investigate the effect of thoracoscopic radical resection of lung cancer in the treatment of elderly patients with non-small cell lung cancer and related factors of postoperative survival rate.Methods A total of 103 patients with non-small cell lung cancer who accepted radical resection of lung cancer from May 2015 to May 2016 were retrospective analysis, including 54 cases in thoracoscopic group and 49 cases in thoracotomy group.The drainage tube removal days, hospitalization days, incidence of complications and 3-year survival rate were compared between the two groups, and the related factors affecting the survival rate of thoracic patients were analyzed.Results The incidence of postoperative complications was lower than that in the thoractomy group, the number of days after surgery, and the number of days of drainage tube in the thoracoscopic group were shorter than those in the thoracotomy group (P＜0.05).Age ≥65 years old and lymph node metastasis were independent risk factors affecting the survival rate of thoracoscopic surgery group (P＜0.05).Conclusion The thoracoscopic surgery in the treatment of elderly patients with non-small cell lung cancer has less trauma, faster recovery after surgery, and has a significant effect.
2020 Vol. 27 (8): 80-82 [Abstract] ( 77 ) HTML (30 KB)  PDF  (0 KB)  ( 13 )
83 Clinical effect of transverse circular suture of uterus combined with Carboprost Tromethamine in the treatment of hemorrhage during cesarean section
YANG Dong-qun； ZHANG Ying-yu； ZHOU Wen-juan
Objective To explore the clinical effect of transverse uterus ring binding combined with Carboprost Tromethamine in the treatment of postpartum hemorrhage in cesarean section.Methods A total of 383 cases cesarean section hemorrhage patients in our hospital from January to December 2018 were selected and divided into the control group (admitted to hospital from January to May 2018, 189 cases, received the treatment of uterine gauze ring binding combined with Carboprost Tromethamine) and the observation group (admitted to hospital from June to December 2018, 194 cases, received the treatment of transverse uterus ring binding combined with Carboprost Tromethamine) according to the time of admission.The clinical efficacy, operation time, bleeding time, intraoperative blood transfusion rate, uterine excision rate, intraoperative blood loss, blood loss after delivery in 2 and 24 h, lochia debridement time, length of hospital stay and occurrence of postoperative complications were compared between the two groups.Results The total effective rate of observation group was higher than that of the control group(P＜0.05).The operation time,hemostasis time and postoperative hospital stay of the observation group were shorter than that of the control group (P＜0.05).The amount of intraoperative blood loss and the amount of bleeding at 2 and 24 h after operation in the observation group were less than that in the control group (P＜0.05).The intraoperative blood transfusion rate, hysterectomy rate and postoperative complicati on rate in the observation group were lower than those in the control group(P＜0.05）.Conclusion The treatment of transverse uterus ring binding combined with Carboprost Tromethamine is effective and safe in the treatment of postpartum hemorrhage incesarean section with better hemostatic effect, which is worthy to be popularized and applied in clinic.
2020 Vol. 27 (8): 83-86 [Abstract] ( 92 ) HTML (38 KB)  PDF  (0 KB)  ( 4 )
87 Comparison of clinical efficacy between modified vaginal hysterectomy and abdominal hysterectomy and its impact on body stress response
SHA Zhi-liu
Objective To compare the clinical efficacy of modified vaginal hysterectomy and abdominal hysterectomy and its impact on the body′s stress response.Methods From July 2016 to March 2019, 200 patients who were going to undergo hysterectomy in our hospital were selected as subjects.According to the different surgical methods, they were divided into modified vaginal hysterectomy group (n=100) and abdominal hysterectomy group (n=100).The changes of stress response, operation and postoperative complications were compared between the two groups.Results The levels of interleukin-6 (IL-6) and C-reactive protein (CRP) in the modified vaginal hysterectomy group were lower than those in the abdominal hysterectomy group, and the differences were statistically significant (P＜0.05).The levels of IL-6 and CRP were higher than those before operation in the two groups (P＜0.05).The intraoperative bleeding in the modified vaginal hysterectomy group was less than that in the abdominal hysterectomy group.The operation time, postoperative exhaust time and the time of activities after operation were shorter than those of the abdominal hysterectomy group,with statistical differences (P＜0.05).The total incidence of postoperative complications in the modified vaginal hysterectomy group was lower than that of abdominal hysterectomy, with statistical difference (P＜0.05).Conclusion Compared with abdominal hysterectomy, modified vaginal hysterectomy can play an important role in the operation and is applicable for more patients.Because it has less restriction, shortens the operation time, reduces the intraoperative bleeding, decreases the levels of IL-6 and CRP, and effectively control the occurrence of complications.
2020 Vol. 27 (8): 87-89 [Abstract] ( 89 ) HTML (32 KB)  PDF  (0 KB)  ( 9 )
90 Clinical effect of laparoscopic surgery combined with antibiotics in the treatment of pelvic inflammatory disease
WANG Jin-long; DAI Xiao-yun; WEI Shu
Objective To investigate the clinical effect of laparoscopic surgery combined with antibiotics in the treatment of pelvic inflammatory disease.Methods Fifty patients with pelvic inflammatory disease admitted to our hospital from January 2017 to December 2018 were enrolled in the study.They were divided into control group (25 cases) and study group (25 cases) according to the random number table method.The control group was treated with intravenous drug alone, and patients in the study group were treated with laparoscopic and antibiotic therapy.The normal temperature of the two groups of patients, the normal time of white blood cell recovery, the time of disappearance of abdominal pain, the length of hospital stay, the incidence of pelvic pain, the incidence of menstrual disorders, the incidence of dysmenorrhea and the recurrence rate were compared.Results The normal temperature of the study group was (2.55±0.56) d, the normal time of leukocyte recovery was (2.51±0.41) d, the time of disappearance of abdominal pain was(2.11±0.76) d, and the hospital stay was (6.77±1.21) d.They were shorter than that of the control group (6.53±1.56),(5.36±1.57), (4.79±1.22), (12.23±3.66) d, and the differences were statistically significant (P＜0.05).The incidence of pelvic pain (4.00%), incidence of menstrual disorders (8.00%), incidence of dysmenorrhea (4.00%), and recurrence rate(4.00%) were lower than that of the control group (36.00%, 24.00%, 20.00%, 40.00%), the differences were statistically significant (P＜0.05).Conclusion Laparoscopic surgery and drug-only treatment of pelvic inflammatory disease are effective, can cure pelvic inflammatory disease in a short time, and the recurrence rate of the disease is extremely low,and the treatment effect is remarkable.
2020 Vol. 27 (8): 90-92 [Abstract] ( 66 ) HTML (32 KB)  PDF  (0 KB)  ( 13 )
93 Analysis of feasibility and safety of vaginal delivery in scar pregnancy
LIAO Gui-lian; LIU Lan-yun ; GUO Fang-fang
Objective To analyze the feasibility and safety of vaginal delivery in the pregnancy of scar uterus.Methods The clinical data of 200 maternal women admitted to ourhospital from July to December 2018 were retrospectively analyzed.According to the different modes of delivery, the patients were divided into study group (n=100) and the control group (n=100).In the study group, vaginal delivery was used, while in the control group, patients with scar uterus underwent caesarean section delivery.The maternal prognosis, postpartum hemorrhage, incidence of puerperal infection and neonatal prognosis were compared between the two groups.Results The bleeding volume of the study group was(151.54±29.79) ml, less than that of the control group ([296.90±74.25]ml).The hospitalization time was (3.05±0.60) d in the study group,shorter than that of the control group ([7.19±0.59]d).The hospitalization cost was (2962.27±460.45) yuan in the study group, lower than that of the control group ([5526.42±420.70]yuan), with statistical differerces (P＜0.05).There was no uterine rupture in the two groups.The incidence of postpartum hemorrhage in the study group was 4%and the incidence of puerperal infection was 0%, which were lower than those of the control group of 12% and 5% (P＜0.05).The Apgar scores of the newborns and neonatal weight in the study and control groups were (9.22±0.60) and(9.36±0.67) points, and (3322.39±201.05) and (3382.09±246.93) g.The incidence of neonatal wet lung was 0% and 2%in the two groups, without statistical differences (P＞0.05).Conclusion Reasonable grasp of indications, vaginal delivery in pregnant women with scar uterus is feasible and safe, and the effect of postpartum recovery is remarkable.
2020 Vol. 27 (8): 93-95 [Abstract] ( 60 ) HTML (33 KB)  PDF  (0 KB)  ( 11 )
96 Application value of painless delivery technology in clinical delivery of obstetrics
ZHOU Yan; LUO Jian-gang; GUAN Xiu-ying; AI Hong-yun; SONG Zhi-gang
Objective To explore the application value of painless delivery technology in clinical delivery of obstetrics.Methods A total of 120 women who gave birth to our hospital from August 2018 to June 2019 were selected, they were divided into observation group and control group according to the willingness of the mother to give birth, 60 cases in each group.The observation group underwent painless delivery techniques, and the control group underwent routine delivery techniques, the analgesic efficacy, duration of labor, and delivery outcomes of the two groups of women were compared.Results The total effective rate of analgesia in the observation group was higher than that in the control group, and the difference was statistically significant (P＜0.05).The first labor time and total labor time of the observation group were shorter those the control group, and the differences were statistically significant (P＜0.05).The cesarean section rate of the observation group was lower than that of the control group (P＜0.05).There was no significant difference in the incidence of postpartum hemorrhage and neonatal asphyxia between the two groups (P＞0.05).Conclusion Use of painless delivery technology in clinical obstetrics, it can effectively reduce the pain of childbirth, improve the outcome of delivery and reduce the time of labor, and can be used in clinical practice.
2020 Vol. 27 (8): 96-98 [Abstract] ( 74 ) HTML (32 KB)  PDF  (0 KB)  ( 8 )
99 Clinical comparison of vaginal hysteromyoma removal and laparoscopic myomectomy for uterine fibroids
WU Dong-lan; LIANG Yin-hua; LI Chun-ling
Objective To compare the clinical effects of vaginal hysteromyoma removal and laparoscopic myomectomy for uterine fibroids.Methods Eighty patients with uterine fibroids admitted to our hospital from June 2018 to January 2019 were selected as subjects.According to random number table method, they was divided into control group (n=40)and observation group（n=40）.In the control group, laparoscopic myomectomy was performed.Patients in the observation group were treated with vaginal hysteromyoma removal.The therapeutic effects, perioperative related indicators,serum sex hormone levels and adverse reactions were observed in the two groups.Results The operation time of the observation group was shorter than that of the control group, and the intraoperative blood loss was less than that of the control group，the differences were statistically significant (P＜0.05).The levels of follicle stimulating hormone and luteinizing hormone in the two groups were higher than those before surgery and estradiol was lower than that before surgery，the differences were statistically significant (P＜0.05).There was no significant difference in E2 and FSH between the two groups at 6 months after operation (P＞0.05).There was no significant difference in the total effective rate and adverse reactions between the two groups (P＞0.05).Conclusion Both vaginal hysteromyoma removal and laparoscopic myomectomy have significant effects in the treatment of uterine fibroids.The vaginal hysteromyoma removal surgery has a short operation time and less intraoperative blood loss.Yin-type uterine fibroids removal is the preferred treatment option.
2020 Vol. 27 (8): 99-101 [Abstract] ( 68 ) HTML (33 KB)  PDF  (0 KB)  ( 9 )
102 Clinical effect of Pavlik sling in the treatment of developmental dysplasia of hip in infants aged 0-6 months
LIU Zai-xin; GAO Fu-tang
Objective To investigate the clinical effect of Pavlik sling in the treatment of developmental dysplasia of the hip in infants aged 0-6 months.Methods Eighty infants with developmental dysplasia of the hip from 0 to 6 months were selected for diagnosis and treatment in the hospital.By means of random grouping, all the infants were divided into two groups: control group and observation group, 40 cases in each group.The observation group was treated with Pavlik sling, while in the control group, closed reduction and plaster fixation in human position was performed,and the follow-up period was observed.Ultrasound examination of hip joint development was performed every two weeks.Suspension treatment lasted for six to twenty weeks.The average follow-up time ranged from eight months.The total effective rate and complication rate of the two groups after different treatment were compared and observed.Results The total effective rate of the observation group was higher than that of the control group, and the total incidence of complications was lower than that of the control group (P＜0.05).Conclusion Pavlik sling treatment can significantly improve the treatment efficiency of infants reduce the long-term residual deformities of infants in the treatment process,and reduce the incidence of complications, which is worthy of wide promotion and application in the medical field.
2020 Vol. 27 (8): 102-104 [Abstract] ( 59 ) HTML (30 KB)  PDF  (0 KB)  ( 7 )
105 Influence of co-management of physicians, nutritionists and psychologist on blood glucose control and pregnancy outcome in patients with gestational diabetes
LIU Yan-li； ZHONG Yi-chun； CHEN Xiao-zheng； HE Jian-min； LIN Hui-qing； CHEN Xiang-hua
Objective To investigate the effect of co-management of physicians, nutritionists and psychologists on blood glucose control and pregnancy outcome in patients with gestational diabetes mellitus (GDM).Methods A total of 120 patients with gestational diabetes mellitus who were treated and delivered in our hospital from February 2016 to December 2018 were selected as the research objects.The patients were coded in order of visit and divided into observation group and control group by random number table method, with 60 cases in each group.Routine management was adopted in the control group, while co-management of physicians, nutritionists and psychologists were used in the observation group.The fasting blood glucose, 2 h postprandial blood glucose level, treatment compliance before delivery,self-management ability, pregnancy outcomes and neonatal outcomes were compared between the two groups.Results After the intervention, fasting blood glucose and 2 h postprandial blood glucose of the two groups were lower than those before the intervention, and the differences were statistically significant (P＜0.05).After intervention, there was no statistically significant difference in fasting blood glucose and 2 h postprandial blood glucose between the two groups (P＞0.05).The complete compliance rate and total compliance rate of the observation group were higher than those of the control group, and the non-compliance rate was lower than that of the control group, with statistically significant differences (P＜0.05).The scores of self-management attitude, diet compliance, exercise problems and blood glucose monitoring problems in the observation group were higher than those in the control group, with statistically significant differences (P＜0.05).The rate of natural delivery in the observation group was higher than that in the control group, and the rate of cesarean section was lower than that in the control group, with statistically significant differences (P＜0.05).The overall incidence of adverse pregnancy outcomes of puerperae in the observation group was lower than that in the control group, and the difference was statistically significant (P＜0.05).The overall incidence of adverse outcomes of newborn in the observation group was lower than that in the control group, and the difference was statistically significant(P＜0.05).Conclusion Co-management of physicians, nutritionists and psychologists for specific dietary arrangements,exercise guidance, psychological counseling and blood glucose control through Wechat platform, so as to improve the compliance and self-management ability of patients with gestational diabetes mellitus and effectively reduce maternal and infant complications.
2020 Vol. 27 (8): 105-108转112 [Abstract] ( 53 ) HTML (41 KB)  PDF  (0 KB)  ( 11 )
109 Clinical effect of laparoscopic high ligation of sacral sac in the treatment of pediatric inguinal hernia
DENG Fu-qiang； YANG Hai； LI Yi-yu
Objective To investigate the effectiveness of laparoscopic high ligation of sacral sac in the treatment of pediatric inguinal hernia and its effect on complications.Methods A total of 100 children with inguinal hernia who were admitted to our hospital from June 2018 to June 2019 were selected and divided into control group and observation group according to random number table method, 50 cases in each group.The observation group was treated with laparoscopic high-level ligation of the umbilical sac, and the control group underwent classic transumbilical laparoscopic high ligation of the hernia sac.The intraoperative blood loss, operation time, hospital stay, postoperative complication rate, incision scar (scarring rate) and recurrence rate were compared between the two groups.Results There was no significant difference in intraoperative blood loss and operation time between the two groups (P＞0.05).The hospitalization time and incision pain duration in the observation group were shorter than those in the control group (P＜0.05), and the total incidence of postoperative complications in the observation group was lower than that in the control group, the differences were statistically significant (P＜0.05).There was no significant difference in recurrence rate between the two groups at 30 days after operation (P＞0.05).Conclusions Umbilical single-site laparoscopic high ligation of the hernia sac in the treatment of indirect inguinal hernia does not destroy the umbilical ring.The postoperative complications are reduced, and the incision is relatively beautiful and easy to be accepted by patients.It is worthy of promotion, but the operation is relatively more difficult.The surgeon has high technical requirements.
2020 Vol. 27 (8): 109-112 [Abstract] ( 68 ) HTML (36 KB)  PDF  (0 KB)  ( 14 )
113 Relationship between strabismus and ametropia in civil aviation medical selection for student pilots recruitment
SHEN Fu-rong； JIANG Ji-wen； WANG Yi-rong； YANG Ke
Objective To explore the relationship between strabismus and ametropia in medical selection for healthy student pilots of the Civil Aviation Flight University of China.Methods The detection of strabismus in the physical examination of our school from November 2018 to March 2019 was analyzed retrospectively.According to the difference of naked eye far vision, strabismus was divided into three groups: emmetropia group, monocular ametropia group and binocular ametropia group.The strabismus in different groups were compared.According to whether or not to wear glasses for correction, the patients were divided into two groups: the group with glasses for correction and the group without glasses for correction.Results A total of 193 cases of strabismus were detected, including dominant strabismus and recessive strabismus,41 cases(21.24%)of emmetropia group with strabismus,58 cases(30.05%)of monocular ametropia group with strabismus, and 94 cases (48.70%) of binocular ametropia group with strabismus.The exotropia rate of binocular ametropia group and emmetropia group were higher than that of monocular ametropia group, and the exophoria rate were lower than that of monocular ametropia group, and the differences were statistically significant（P＜0.05）.There were 80 cases (41.45%) in the ametropia correction group and 72 cases (37.31%) in the ametropia uncorrection group.The exotropia rate in the uncorrected ametropia group was higher than that in the emmetropia group and ametropia correction group, and the differences were statistically significant (P＜0.05).The implicit slope and upper implicit slope of the uncorrected group were lower than those of the correction ametropia group, and the differences were statistically significant (P＜0.05).Conclusion The strabismus detection rate of the healthy people recruited by our university is mainly ametropia, among which the strabismus detection rate of those who have not been corrected by wearing glasses is higher.Ametropia should be corrected timely and scientifically.
2020 Vol. 27 (8): 113-116 [Abstract] ( 66 ) HTML (36 KB)  PDF  (0 KB)  ( 13 )
117 Clinical effect of auxiliary filling with Ornidazole Mixture in the treatment of endodontic disease
LIU Qing-hua； LIN Qi； LAN Xiao-ting； WEI Hua
Objective To discuss the clinical effect of auxiliary filling with Ornidazole Mixture in the treatment of endodontic disease.Methods A total of 130 endodontic disease patients treated from January 2016 to December 2018 in our hospital were selected as research subjects.Patients were randomly assigned to control group (n=65) and test group(n=65) according to the random grouping mode of the computer terminal.The control group was filled with dry pulp agent; the test group was filled with Ornidazole Mixture.After systematic therapy, the comprehensive effects, 3-month treatment prognosis and overall adverse reactions rate were compared.Results The clinical effective rate in the test group (96.92%) was higher than that in the control group (80.00%), the difference was statistically significant (P＜0.05);the overall adverse reactions rate in the test group (3.07%) was lower than that in the control group (27.69%), the difference was statistically significant (P＜0.05); the chewing efficiency and occlusal force in the test group was higher than that in the control group, the difference was statistically significant (P＜0.05); the activity of daily living scores in the test group were higher than those in the control group, the differences were statistically significant (P＜0.05).Conclusion Theauxiliary filling with Ornidazole Mixture has better effect on endodontic disease, which can reduce the adverse reactions, promote the chewing function recovery and improve the activity of daily living.It can be feasibly applied in clinical practice.
2020 Vol. 27 (8): 117-120 [Abstract] ( 69 ) HTML (40 KB)  PDF  (0 KB)  ( 14 )
121 Effect of Probiotics Buccal Tablets combined with basic periodontal treatment on oral microecology of patients with chronic periodontitis accompanied by bad breath
LI Yan； WU Hai-yan； WANG Yu-e； LI Hui-shan
Objective To explore the effect of Probiotics Buccal Tablets combined with basic periodontal treatment on oral microecology of patients with chronic periodontitis accompanied by bad breath.Methods A total of 74 patients with chronic periodontitis accompanied by bad breath treated in our hospital from February 2016 to February 2019 were selected as the research subjects.They were divided into the observation group (n=37) and the control group (n=37) according to the random number table method.Basic periodontal treatment was used in the control group.In the observation group, Probiotics Buccal Tablets combined with basic periodontal treatment was adopted.The salivary interleukin-6, interleukin-10, oral pathogenic flora, matrix metalloproteinase-9 levels and treatment effect were compared in the two groups.Results The levels of salivary interleukin-6 and matrix metalloproteinase-9 in the observation group were lower than those in the control group, the differences were statistically significant (P＜0.05).The level of interleukin-10 in the observation group was higher than that in the control group, and the difference was statistically significant (P＜0.05).The oral pathogenic bacteria in the observation group were lower than those in the control group, and the differences were statistically significant (P＜0.05).The total effectiveness rate of clinical treatment in the observation group was higher than that in the control group, and the difference was statistically significant (P＜0.05).Conclusion In patients with chronic periodontitis accompanied by bad breath, the use of Probiotics Buccal Tablets combined with periodontal basic treatment can effectively reduce the levels of interleukin-6 and matrix metalloproteinase-9, increase interleukin-10 level, and improve oral pathogenic flora.It can obtain a favorable clinical treatment effect, with certain application value, and should be widely used in the clinic.
2020 Vol. 27 (8): 121-123 [Abstract] ( 67 ) HTML (32 KB)  PDF  (0 KB)  ( 11 )
124 Clinical effect of penetrating resin combined with Beyond cold light whitening instrument in the treatment of severe dental fluorosis
CHEN Jia-xin； HUANG Zhi-chang； LI Kun-jie
Objective To explore clinical effect of penetrating resin combined with Beyond cold light whitening instrument in the treatment of severe dental fluorosis.Methods Fifty patients with severe dental fluorosis treated in our hospital from January 2015 to January 2017 were selected as the research subjects, they were divided into control group(25 cases) and observation group (25 cases) according to the random number table method.The control group was treated with Beyond cold light whitening device, the observation group was treated with penetrating resin combined with Beyond cold light whitening device.After 2 years follow-up, the therapeutic effect and satisfaction of the two groups were compared.Results There was no significant difference the effective rate of the control group at 3 and 6 months after treatment compared with 1 week after treatment (P＞0.05).The effective rate of the control group in the first and second year after treatment was lower than that in the first week, the difference was statistically significant (P＜0.05).There was no significant difference in the effective rate of the observation group at 3, 6 months, 1 and 2 years after treatment compared with 1 week after treatment (P＞0.05).There was no significant difference in the treatment efficiency between the two groups after 1 week, 3 months, and 2 years (P＞0.05).The treatment group at 6 months and 1 year after treatment was more effective than the control group, the difference was statistically significant (P＜0.05).The treatment satisfaction of the observation group was higher than that of the control group, the difference was statistically significant (P＜0.05).Conclusion Penetrating resin combined with Beyond cold light whitening instrument to treat severe dental fluorosis can improve the clinical treatment effect and satisfaction of patients.
2020 Vol. 27 (8): 124-126转130 [Abstract] ( 74 ) HTML (30 KB)  PDF  (0 KB)  ( 12 )
127 Clinical effect of Olopatadine combined with Polyethylene Glycol Eye Drops in the treatment of allergic conjunctivitis
XIU Xin-xin； ZHAO Jian
Objective To explore the clinical effect of Olopatadine combined with Polyethylene Glycol Eye Drops in the treatment of allergic conjunctivitis.Methods Atota of 120 patients (120 eyes) with allergic conjunctivitis who were treated in our hospital from January 2018 to June 2019 were selected, and divided into test group and control group by random number table method, with 60 cases (60 eyes) in each group.The control group was treated with Olopatadine Eye Drops.The test group was treated with Olopatadine and Polyethylene Glycol Eye Drops.The changes of clinical symptoms and signs, break up time (BUT), tear secretion test (Schimer Ⅰtest), corneal fluorescein staining, treatment effect and adverse reaction were compared between the two groups.Results There was no significant difference between the two groups in clinical symptoms and signs, BUT, schimer Ⅰtest and corneal fluorescein staining before treatment(P＞0.05).The symptom and sign scores and corneal fluorescein staining scores of the two groups after 2 weeks of treatment were lower than those before treatment, BUT and SchimerⅠtest were longer than those before treatment, and the differences were statistically significant (P＜0.05).The symptom and sign score and corneal fluorescein staining score of the test group were lower than those of the control group, BUT and SchimerⅠtest were longer than those of the control group, the differences were statistically significant (P＜0.05).The total effective rate of the test group was 91.7%, which was higher than that of control group (78.3%), and the difference was statistically significant (P＜0.05).All patients did not have adverse reactions during treatment, the original disease and ocular symptoms were not aggravated.Conclusion The clinical effect of Olopatadine combined with Polyethylene Glycol Eye Drops in the treatment of allergic conjunctivitis is significant, and with less adverse reactions, easy to operate.So it is a safe and effective treatment, which worth to promote the application in clinic.
2020 Vol. 27 (8): 127-130 [Abstract] ( 85 ) HTML (35 KB)  PDF  (0 KB)  ( 11 )
131 Application of minimally invasive circumcision in patients with oral implant
YANG Yu-wen ； ZHANG Hua； HUANG Wan-li； HUANG Chun-tao； CHEN Jie-min； WEI Rui-tao； ZHOU Jia-xu； CHEN Xiao-luan
Objective To explore the application of minimally invasive circumcision in in patients with oral implant.Methods A total of 60 patients with oral implantation in our hospital from January 2017 to December 2018 were selected as the research objects, they were divided into the control group (30 cases) and the observation group (30 cases) according to the random number table method.The control group used traditional flap implantation, and the observation group used minimally invasive circumcision.After 6 months follow-up, the implant success rate, operation time, visual analog scale (VAS) score on day 1 after operation, alveolar bone absorption, implant stability coefficient, gingival papilla height and aesthetic degree of the two groups were compared.Results The success rate of oral implantation in the observation group was higher than that of the control group, the operation time was shorter than that of the control group,the VAS score on the first day after operation was lower than that of the control group, the differences were statistically significant (P＜0.05).The alveolar zygomatic bone absorption in the observation group was lower than that in the control group, the difference was statistically significant (P＜0.05).There was no significant difference in implant stability coefficient and gingival nipple height between the two groups (P＞0.05).The aesthetic score of the observation group was higher than that of the control group, the difference was statistically significant (P＜0.05).Conclusion Minimally invasive circumcision can improve the success rate of implants and the aesthetics of implants in patients with oral implants,shorten the operation time, reduce the degree of postoperative pain, and reduce the alveolar zygomatic bone absorption.
2020 Vol. 27 (8): 131-133 [Abstract] ( 66 ) HTML (33 KB)  PDF  (0 KB)  ( 10 )
134 Application value of carotid artery ultrasound in early diagnosis of stroke
CHEN Xiao-lan
Objective To analyze the application value of carotid artery ultrasound in the early diagnosis of stroke.Methods From January 2012 to October 2018, 50 patients with early stroke who had undergone carotid ultrasound examination in our hospital were selected as stroke group.In addition, 50 non stroke patients who underwent carotid ultrasound examination at the same time were selected as the healthy group.The carotid artery wall thickness, carotid hemodynamic index and carotid stenosis were compared between the two groups, and the diagnostic value of carotid ultrasound was observed.Results The intima-media thickness of the internal, external and common carotid arteries in stroke group were higher than those in healthy group, and the differences were statistically significant (P＜0.05).The vascular resistance index (RI) and the peak systolic velocity (PSV) of common carotid artery and internal carotid artery in stroke group were higher than those in healthy group, and the differences were statistically significant (P＜0.05).The degree of carotid stenosisin stroke group was heavier than that in the healthy group, and the difference was statistically significant (P＜0.05).Conclusion Carotid artery ultrasound can confirm whether the carotid is stenosed or not and the degree of carotid stenosis, and can well and truly reflect the hemodynamic index of the patients′ carotid artery, which is helpful for the early diagnosis of carotid artery and provides some basis for the treatment of patients in clinics.
2020 Vol. 27 (8): 134-136 [Abstract] ( 69 ) HTML (31 KB)  PDF  (0 KB)  ( 9 )
137 Value of ultrasound elastography and X-ray molybdenum target in the classification of breast masses by BI-RADS
LUO Yu-duan； WANG Jia-xin； CHEN Man-qing； DU Yu-hong
Objective To explore the value of ultrasound elastography and X-ray molybdenum target in the classification of breast masses by BI-RADS.Methods From January 2017 to December 2018, 55 patients with breast masses treated in our hospital were selected as the study objects, and all of them were diagnosed by ultrasound elastography and X-ray molybdenum target BI-RADS classification.The related indicators as well as the value to the diagnosis of breast lumps in different diameter were compared between tultrasound elastography and mammography BI-RADS.Results The histopathologic results showed 35 malignant lesions and 20 benign lesions.There was no significant difference in the accuracy of ultrasound elastography BI-RADS classification in diagnosis of breast masses compared with molybdenum target BI-RADS classification, and the difference was statistically significant (P＞0.05).The sensitivity,specificity and accuracy of ultrasound elastography BI-RADS classification in diagnosing tumors less than 1 cm in diameter were lower than those of X-ray mammography BI-RADS classification, and the difference was statistically significant (P＞0.05).There was no significant difference in sensitivity, specificity and accuracy of diagnosis between 1-2 cm diameter masses and BI-RADS classification (P＞0.05).The sensitivity, specificity and accuracy of diagnosing tumors larger than 2 cm in diameter were higher than those of X-ray mammography BI-RADS classification diagnosis,and the difference was statistically significant (P＞0.05).Conclusion Both ultrasound elastography and X-ray mammography BI-RADS have a high diagnostic value to breast lumps classification, with their own advantages in the diagnosis of breast lumps in different diameter.
2020 Vol. 27 (8): 137-139转143 [Abstract] ( 57 ) HTML (32 KB)  PDF  (0 KB)  ( 15 )
140 Clinical effect of bee acupuncture in the treatment of non-specific low back pain on cold dampness type
NI Shan； LIU Yi-chang
Objective To explore the clinical effect of bee acupuncture in the treatment of non-specific low back pain on cold dampness type.Methods A total of 68 low back pain on cold dampness type patients admitted to the Chinese Medicine Department of Heilongjiang Red Cross (Songong General) Hospital from October 2017 to October 2018 were selected as the research objects, they were divided into observation group (34 cases) and control group (34 cases) according to the random number table method.The observation group was treated with bee acupuncture, the control group was treated with acupuncture, the two groups were treated 24 times.The treatment effect, visual analog scale (VAS)score and Japan orthopaedic association (JOA) score before and after treatment were compared between the two groups.Results The total effective rate of treatment in the observation group was higher than that in the control group, the difference was statistically significant (P＜0.05).After treatment, the VAS score of the two groups was lower than before treatment, the JOA score was higher than before treatment, the VAS score of the observation group was lower than that of the control group, the JOA score was higher than that of the control group, the differences were statistically significant (P＜0.05).Conclusion Bee acupuncture therapy for cold-wet non-specific low back pain can improve the treatment effect of patients, alleviate the pain level of patients, and improve the lumbar spine function of patients.
2020 Vol. 27 (8): 140-143 [Abstract] ( 77 ) HTML (36 KB)  PDF  (0 KB)  ( 13 )
144 Clinical effect of Kidney-warming Monkshood-separated Moxibustion on leukocytopenia caused by chemotherapy
LI Ming-xiu； LIU Yan； ZHANG Cong； LIANG Yi-hui； TANG Hong-mei
Objective To investigate the clinical effect of Kidney-warming Monkshood-separated Moxibustion on leukocytopenia caused by chemotherapy.Methods Sixty patients who were diagnosed as malignant tumors and developed leukocytopenia caused by chemotherapy in our hospital from October 2017 to May 2019 were selected as subjects.They were divided into the control group (n=30) and treatment group (n=30) by envelope method.The control group was treated with Batyl Alcohol, and the treatment group was treated with Kidney-warming Monkshood-separated Moxibustion.The treatment effect, therapeutic indicators, and quality of life were compared between the two groups.Results The total effective rate in the treatment group was higher than that in the control group, the difference was statistically significant (P＜0.05).The hospital stay in the treatment group was shorter than that in the control group, the number of using human granulocyte colony-stimulating factor (G-CSF) and treatment cost were less than those in the control group, the differences were statistically significant (P＜0.05).Before treatment, there were no significant differences in the scores of physical health, mental health, social relations, and surrounding environment between the two groups (P＞0.05).After treatment, the quality of life scores including physical health, mental health, social relationship, and surrounding environment in the treatment group were higher than those in the control group, the differences were statistically significant (P＜0.05).Conclusion The use of Kidney-warming Monkshood-separated Moxibustion for patients with leukocytopenia caused by chemotherapy can effectively enhance the treatment efficiency, further optimize the therapeutic indicators, and greatly improve the quality of life.It is worth promoting in clinical treatment of patients with leukocytopenia caused by chemotherapy.
2020 Vol. 27 (8): 144-146转154 [Abstract] ( 63 ) HTML (37 KB)  PDF  (0 KB)  ( 9 )
147 Clinical effect of honglong moxibustion in the treatment of lumbar intervertebral disc protrusion of cold-dampness type
WANG Hui； LI Ju-lian； WANG Wei； LEI Shou-qing
Objective To explore the clinical effect of honglong moxibustion in the treatment of lumbar intervertebral disc protrusion of cold-dampness type.Methods Sixty patients with lumbar intervertebral disc protrusion of colddampness type treated in our hospital from September 2016 to March 2018 were selected as research subjects.According to the random number table method, the patients were divided into the treatment group (30 cases) and the control group (30 cases).The treatment group was treated with honglong moxibustion, and the control group was treated with warm acupuncture.The clinical effect, scores of Japanese Orthopaedic Association (JOA) and visual analogue scale(VAS) before and treatment in the two groups were observed.Results After treatment, the JOA score of the treatment group was higher than that of the control group, and the difference was statistically significant (P＜0.05).The VAS score after treatment of the treatment group was lower than that of the control group, and the difference was statistically significant (P＜0.05).The cure rate of patients in the treatment group was 70.0%, which was higher than that in the control group accounting for 56.7%, and the difference was statistically significant (P＜0.05).There was no significant difference in the total effective rate of treatment between the treatment group (93.3%) and the control group (90.0%) (P＞0.05).Conclusion The effect of honglong moxibustion in the treatment of the lumbar intervertebral disc protrusion of colddampness type is better, which can effectively relieve the patients′ pain and improve their symptom.
2020 Vol. 27 (8): 147-150 [Abstract] ( 89 ) HTML (42 KB)  PDF  (0 KB)  ( 11 )
151 Clinical effect of Shentong Zhuyu Decoction combined with surgery in the treatment of proximal humerus fracture
YUAN Sheng-chao； LIN Fu-chun； YE Zhong-sen
Objective To investigate the clinical effect of Shentong Zhuyu Decoction combined with surgery in the treatment of proximal humerus fracture.Methods A total of 86 patients with proximal humerus fractures who were treated in our hospital orthopaedics department from January 2017 to March 2018 were selected as the research subjects, they were divided into control group and observation group according to whether the Shentong Zhuyu Decoction was used, with 43 cases in each group.The control group was treated with the proximal humerus anatomic locking plate surgery, the observation group was treated with the Shentong Zhuyu Decoction combined with the proximal humerus anatomic locking plate surgery.The excellent rate of shoulder function, various recovery indexes, and the total incidence of complications were compared between the two groups; the X-ray and 3D CT images of the observation group before and after surgery were analyzed.Results The excellent and good rate of shoulder joint function in the observation group was 95.35%, higher than 79.07% in the control group, the difference was statistically significant (P＜0.05).The swelling resolution time, hospitalization time, epiphyseal appearance time and fracture healing time in the observation group were shorter than those in the control group, the differences were statistically significant (P＜0.05).The total incidence of complications in the observation group was lower than that in the control group, the difference was statistically significant (P＜0.05).Conclusion Treatment of proximal humeral fractures with Shentong Zhuyu Decoction can improve the excellent rate of shoulder joint function, shorten the swelling subsidence time, hospitalization time, epiphyseal appearance time and fracture healing time, and reduce the incidence of complications.Clinical application.
2020 Vol. 27 (8): 151-154 [Abstract] ( 75 ) HTML (36 KB)  PDF  (0 KB)  ( 9 )
155 Discussion on the application of relieving depression in gastroesophageal reflux disease
ZENG Mu-ye； HUANG Liu-xiang
Gastroesophageal reflux disease is a common disease of the digestive system.In the category of traditional Chinese medicine, it belongs to "acid regurgitation" "ructus" "heartburn" "epigastric upset" "dysphagia" "globus hysteriocus", etc.In recent years, the incidence rate has increased year by year.If the effective treatment is not taken in time, the life quality of patients is seriously affected.Although Western medicine treatment can effectively alleviate the symptoms of patients, it has no good effect on the repeatability of symptoms.Traditional Chinese medicine treatment has unique curative effect on the disease, and it has certain advantages in improving patients′ symptoms, reducing recurrence and improving cure rate.In the clinical learning process and reading ancient Chinese books, it is known that the occurrence and development of gastroesophageal reflux disease is related to "depression".This article firstly shows the meaning and development of "depression syndrome", then the etiology and pathogenesis of gastroesophageal reflux disease is demonstrated from the perspective of "depression causing disease".Finally, the treatment based on "relieving depression" is illustrated.Through the differentiation of syndromes, the treatment methods such as dispersing liver and regulating qi, activating qi and promoting blood, clearing heat and resolving dampness, reducing qi and removing phlegm, benefiting qi and replenishing spleen, are flexibly adopted, and the importance to the a djustment of spirit, diet and lifestyle was attached to achieve curative effect.
2020 Vol. 27 (8): 155-158 [Abstract] ( 55 ) HTML (38 KB)  PDF  (0 KB)  ( 10 )
159 Application effect of food coliform indirect counting method in water quality coliform monitoring
ZHAO Wei-hong； XU Qiu-qin； PEI Yong-jun； MAO Yun-bin； HUANG Zeng； ZOU Jin-qun； ZHAN Zhuo-peng
Objective To explore the effect of indirect counting method (MPN method) in GB 4789.3-2016 "National Food Safety Standard for food microbiology test—Coliforms Count" on detecting coliforms in water.Methods The water samples were inciuded urban drinking water, rural drinking water, reservoir water, and water source from Fengcheng city from October 2017 to April 2018.The coliforms in water were detected by the MPN method in GB 4789.3-2016 and the total coliforms MPN method in GB/T 5750.12-2006 "Standard examination methods for drinking water—Microbilolgical parameters", separately.The correlation between the two methods for detecting coliform bacteria was verified.The manpower, material resources, cost, time and the positive rate of coliform bacteria detected by the two methods were compared.Results The consistency of two MPN methods to detect coliform group in water quality was good(Kappa=0.97).There was no significant difference in the positive rate of coliform detected by two MPN methods (P＞0.05).The instrument cost, reagent cost and labor cost of food coliform group MPN method were lower than those of water coliform group MPN method, and the consumption time was shorter than that of water coliform group MPN method, and the differences were statistically significant (P＜0.05).Conclusion MPN method of food coliform group can replace MPN method of water coliform group to detect coliform group of water quality, which can greatly save manpower, material and financial resources.
2020 Vol. 27 (8): 159-161转165 [Abstract] ( 57 ) HTML (33 KB)  PDF  (0 KB)  ( 11 )
162 Comparative study of four items of hemagglutination in different degrees of diffuse intravascular coagulation
JING Feng
Objective Through the detection of prothrombin time (PT), activated partial prothrombin time (APTT), fibrinogen (FIB) content and thrombin time (TT) in different stages of disseminated intravascular coagulation (DIC), to discuss the relationship between the degree of DIC and the four levels of blood coagulation, and to evaluate the value of four items of blood coagulation in the clinical diagnosis of DIC.Methods From March 2018 to April 2019, 90 patients with known DIC related basic diseases were selected.According to early diagnosis, they were divided into hypercoagulable group, the lysozyme group and the fibrinolytic group, with 30 cases in each group.In addition, 30 healthy volunteers in the same period were randomly selected as the control group, and four blood coagulation levels in each group were measured, and the relationship between the four items of hemagglutination and the course of DIC was analyzed.Results PT and APTT of the hypercoagulable group, the lysozyme group and the fibrinolytic group were longer than those of the control group, and the differences were statistically significant (P＜0.05).TT of the lysozyme group and the fibrinolytic group were longer than that of the control group, and FIB was lower than that of the control group, the differences were statistically significant (P＜0.05).There was no significant difference in TT and FIB content between the hypercoagulant group and the control group (P＞0.05).The APTT of the lysozyme group was longer than that of the hypercoagulant group, and the FIB content of the lysozyme group was lower than that of the hypercoagulant group, the differences were statistically significant (P＜0.05).PT, APTT and TT in the fibrinolytic group were longer than those in the hypercoagulant group, and the content of FIB was lower than those in the hypercoagulant group, with statistically significant difference (P＜0.05).PT, APTT and TT in the fibrinolytic group were longer than those in the lysozyme group, and the content of FIB in the fibrinolytic group was lower than that in the lysozyme group, with statistically significant difference (P＜0.05).Linear correlation analysis showed that PT, APTT were positively correlated with the course of DIC (r=0.81, 0.77; P＜0.05).FIB was negatively correlated with the course of DIC (r=-0.72, P＜0.05).TT was not correlated with the course of DIC (P＞0.05).Conclusion The four indexes of hemagglutination have significant differences in different periods of DIC.The early detection and analysis of each index is helpful to the clinical diagnosis of early DIC and the prediction of the development period of DIC.
2020 Vol. 27 (8): 162-165 [Abstract] ( 61 ) HTML (33 KB)  PDF  (0 KB)  ( 16 )
166 Changes and clinical significances of serum amylase, lipase and C-reactive protein levels in patients with acute pancreatitis
LIANG Jian-fu； XIE Xiao-ting
Objective To investigate the changes and clinical significance of serum amylase (AMS), lipase (LPS) and C-reactive protein (CRP) levels in patients with acute pancreatitis (AP).Methods A total of 997 cases of AP patients admitted to our hospital from March 2015 to July 2018 were selected as the AP group, among them, 835 cases were mild and 162 cases were severe.Altogether 1000 cases of healthy subjects who underwent physical examination in our hospital during the same period were selected as the healthy group.The serum AMS, LPS and CRP levels of the two groups were detected and compared.Results The levels of serum AMS, LPS and CRP in the AP group were higher than those in the healthy group, and the differences were statistically significant (P＜0.05).The levels of serum AMS, LPS and CRP of mild and severe patients were higher than those of the healthy group, and the differences were statistically significant (P＜0.05).The levels of serum AMS, LPS and CRP of the severe patients were higher than those of the mild patients, and the differences were statistically significant (P＜0.05).Conclusion The levels of AMS, LPS and CRP of patients with AP are higher.AMS, LPS and CRP can be used as reference indexes in the diagnosis of AP and its severity.
2020 Vol. 27 (8): 166-168 [Abstract] ( 72 ) HTML (32 KB)  PDF  (0 KB)  ( 10 )
169 Evaluation value of serum squamous cell carcinoma antigen, carbohydrate antigen 125 and carbohydrate antigen 199 expression for prognosis of patients with small cell carcinoma of cervix
WANG Qi； WANG Nan； LIU Dan
Objective To explore evaluation value of expression of serum squamous cell carcinoma antigen (SCC), carbohydrate antigen 125 (CA125) and carbohydrate antigen 199 (CA199) for prognosis of patients with small cell carcinoma of cervix (SCCC).Methods A total of 58 patients diagnosed with SCCC in Dalian Maternal and Child Health Hospital from January 2018 to January 2019 were enrolled as the observation group, and 58 healthy women who underwent physical examination during the same period were enrolled as the control group.The levels of SCC, CA125 and CA199 in the control group and in the observation group before and after treatment were detected.According to different prognosis, the SCCC patients were divided into effective treatment group and ineffective treatment group, and the levels of SCC, CA125 and CA199 were compared between the two groups.Results The levels of SCC, CA125 and CA199 in observation group before and after treatment were higher than those in control group, and the differences were statistically significant (P＜0.05).At the fourth month after discharge, of the 58 SCCC patients, there were 36 cases with effective treatment, and 22 cases with ineffective treatment.The levels of SCC, CA125 and CA199 in the ineffective treatment group were higher than those in the effective treatment group, and the differences were statistically significant (P＜0.05).The receiver operating characteristic (ROC) curve analysis showed that the area under the curve (AUC) of the combined detection of SCC, CA125, and CA199 was larger than that of SCC, CA125, and CA199 alone, and the difference was statistically significant (P＜0.05).Conclusion Serum SCC, CA125, CA199 are of relatively higher diagnostic value for SCCC, which can be applied as indexes for prognosis evaluation.
2020 Vol. 27 (8): 169-171 [Abstract] ( 59 ) HTML (32 KB)  PDF  (0 KB)  ( 15 )
172 Application effect of health management in patients with asymptomatic hyperuricemia
LUO Zhen-gen
Objective To explore the application effect of health management in patients with asymptomatic hyperuricemia.Methods A total of 200 patients with asymptomatic hyperuricemia in our hospital from January to December in 2018 were enrolled in the study.The experimental group (n=100) and the control group (n=100) were assigned by computer randomization.In the observation group, routine management was used, while in the experimental group,health management was implemented.The differences in health knowledge awareness rate, body mass index (BMI),blood lipids, hematuria, blood glucose, and blood pressure between the two groups were compared.Results The awareness rates of health knowledge including disease detection, drug use, reasonable exercise, healthy lifestyle, disease hazard, disease risk factors, disease cognition in the experimental group were higher than those in the control group, and the differences were statistically significant (P＜0.05).After intervention, the BMI, blood lipids (triglycerides, cholesterol), blood uric acid, blood glucose, blood pressure (diastolic blood pressure, systolic blood pressure) of the experimental group were lower than those of the control group with statistical differences (P＜0.05).Conclusion Patients with asymptomatic hyperuricemia who receive health management can improve their knowledge of disease and health, and better reduce their levels of blood uric acid, blood lipids, BMI, which is of great significance.
2020 Vol. 27 (8): 172-174 [Abstract] ( 66 ) HTML (31 KB)  PDF  (0 KB)  ( 16 )
175 Application of quality control circle in reducing the number of accidents in automatic dispensing machine in outpatient pharmacy
XU Hua; ZHAO Mei-li; XU Bao-qin
Objective To discuss the application of quality control circle in reducing the number of accidents in automatic dispensing machine in outpatient pharmacy.Methods The staff of outpatient pharmacy set up quality control circle by voluntary registration, the number of failures of automatic dispensing machine before improvement in January to February in 2019 was collected, implemented various activities in strict accordance with the ten steps of quality control circle, analyzed the main causes of failure of automatic dispensing machines from personnel and equipment, drugs, and environmental aspects, formulated corresponding solutions and implemented them, and the number of automatic drug machine failures from June to July in 2019 after improvement was collected.The effectiveness of activities was evaluated.Results The number of failures of the dispensing machine was 330 times before the improvement of the first 14 days,with an average of (24±5) times per day, and the number of failures was 113 times after 14 days of improvement, with an average of (8±2) times per day.Conclusion Through this quality control circle activity, the number of automatic drug delivery machine failures in outpatient pharmacies has been effectively improved, the efficiency of outpatient pharmacies has been improved, and the ability of the circle staff has been strengthened.
2020 Vol. 27 (8): 175-178 [Abstract] ( 88 ) HTML (35 KB)  PDF  (0 KB)  ( 12 )
179 Application value of hospital nursing safety management based on information network platform
LEI Xiao-ping; CHA Hai-yan; PAN Li
Objective To explore the application value of hospital nursing safety management based on information network platform.Methods A total of 24 433 inpatients without information network platform management in our hospital from January to December 2016 were selected as the control group, 23 538 inpatients with information network platform management in our hospital from January to December 2017 were selected as the experimental group.At the same time, there were 301 doctors in each group.The incidence of adverse events in nursing care, the satisfaction of patients and doctors, the rate of qualified nursing were compared between the two groups.Results The incidence rate of warning events, adverse events and uncaused events in the experimental group were lower than those in the control group, the incidence of hidden events was higher than that in the control group, the differences were statistically significant (P＜0.05).The total satisfaction of the patients in the experimental group was higher than that in the control group,the difference was statistically significant (P＜0.05).The qualified rate of nursing quality in the experimental group was higher than that in the control group, the difference was statistically significant (P＜0.05).Conclusion The application of the information network based platform management system in hospital nursing safety management can reduce the occurrence of adverse nursing events, improve the patients′ nursing work satisfaction and the quality of nursing safety management, and is worthy of clinical promotion and application.
2020 Vol. 27 (8): 179-181 [Abstract] ( 64 ) HTML (32 KB)  PDF  (0 KB)  ( 14 )
182 Application of PBL teaching based on "rain classroom" in the course of Adult Nursing of nursing undergraduate
LI Fang; CHEN Xue-lei; CHEN Yun-xiang; YANG Ping; WEI Shao-juan
Objective To investigate the application effect of "rain classroom" combined with PBL teaching in the course of Adult Nursing of nursing undergraduate.Methods From February to June in 2018, 211 full-time nursing undergraduates from two classes of 2016 grade in Guilin Medical University were enrolled as subjects.According to the random sampling method, 107 students in one class were selected as the experimental group, and 104 students in the other class were classified into the control group.In the experimental group, "rain classroom" combined with the PBL teaching was adopted, while in the control group, the PBL teaching alone was used.The final evaluation scores of Adult Nursing were compared between the two groups and the students′ evaluation of teaching in the experimental group was investigated.Results The theoretical results of the final exam showed that the theoretical results of the first and second tests in the experimental group were higher than those in the control group, and the differences were statistically significant (P＜0.05).Most of the participants believed that the "rain classroom" was beneficial to the mastery of knowledge(97.19%), the development of thinking ability (98.13%), the improvement of ability to solve problems (95.33%), the promotion of cooperation and communication between classmates (95.32%), and the improvement of learning enthusiasm(96.26%).Conclusion The PBL teaching based on "rain classroom" can effectively improve the learning enthusiasm and academic record of nursing undergraduates and improve the effect and quality of teaching.
2020 Vol. 27 (8): 182-185 [Abstract] ( 61 ) HTML (42 KB)  PDF  (0 KB)  ( 13 )
186 Application of ideological and political education in the teaching of Neurology
CUI Li; LIU Min; ZHANG Hui; TANG Wei; WANG Wei
Objective To explore the application effect of ideological and political education in the teaching of Neurology.Methods From September 2017 to June 2019, students from the two grades of 2015 and 2016 in Medicine School of Dalian University were randomly selected as the research objects, of whom the students in grade 2015 were used as the control group (60 cases) and the students in grade 2016 were used as the experimental group (60 cases).The control group used traditional teaching methods, and the specific classroom teaching was mainly based on slideshows.The experimental group adopted the curriculum ideological and political teaching method.After the course,the questionnaire survey, test score analysis and peer expert evaluation were used to evaluate.Results The results of the questionnaire survey showed that 85.00% of students thought that ideological and political education could promote the combination of theoretical knowledge and clinical application, 90.00% of students believed that ideological and political education had a certain effect on improving learning motivation and could stimulate learning interest, 81.67% of students reflected that ideological and political education could improve students′ clinical thinking ability, and 88.33%of students reported that ideological and political education could improve the efficiency of knowledge and memory.The scores of the stage test, final exam and additional case analysis questions in the experimental group were higher than those in the control group, and the differences were statistically significant (P＜0.05).Peer experts believed that the application of curriculum ideological and political education in Neurology teaching would be a new way and new method in teaching reform.Conclusion The application of ideological and political education in the teaching of Neurology has a good teaching effect and improves students′ interest in learning.
2020 Vol. 27 (8): 186-189 [Abstract] ( 66 ) HTML (42 KB)  PDF  (0 KB)  ( 8 )
190 Application of mind mapping in the teaching of Traditional Rehabilitation Methodology
DONG Chun-xue; CHEN Peng; HU Bin; CHAI De-jun; LI Liang
As an emerging teaching and learning tool, mind mapping plays an increasingly important role in higher education teaching and has a great positive impact on the teaching process.It helps medical students master relevant learning contents through intuitive and distributed thinking.This paper introduced the mind mapping in rehabilitation professional application of the Traditional Rehabilitation Methodology, analyzed it in teaching and learning efficiency advantages, pointed out that using the mind map would help teachers to expand knowledge network and help students to review the old and new knowledge point, improve the ability to solve clinical problems, by inspiring students′ divergent thinking to develop more clinical practical application ability.The application of mind mapping teaching model has a broad prospect in rehabilitation specialty of higher medical education in China.
2020 Vol. 27 (8): 190-193 [Abstract] ( 58 ) HTML (35 KB)  PDF  (0 KB)  ( 14 )
194 Comparison of the effects between sticking type of insulin pump and traditional insulin pump in the treatment of elderly patients with diabetes mellitus
MAO Yuan-yuan; LIU Xiao-chun
Objective To investigate the clinical effects of sticking type of insulin pump and traditional insulin pump in the treatment of elderly patients with diabetes mellitus (SDM).Methods From January 2018 to May 2019, 60 SDM treat in Yingtan People′s Hospital, Jiangxi Province were selected and divided into study group (n=30) and control group (n=30) according to the different insulin pumps used.The study group was treated with sticking type of insulin pump while the control group were treated with traditional insulin pump.The effects of blood glucose control before treatment and after 2 weeks of treatment, time for blood glucose level reaching the standard, dosage of insulin when blood glucose reached the standard, treatment compliance and satisfaction of the two groups were compared.Results The levels of fasting blood glucose, blood glucose at 2 h after breakfast, blood glucose before sleeping and glycosylated hemoglobin in the study group were lower than those in the control group after 2 weeks of treatment (P＜0.05).The time for blood glucose level reaching the standard in the study group was shorter than that in the control group, and the dosage of insulin when blood glucose reached the standard was less than that in the control group (P＜0.05).The scores of treatment compliance scale and satisfaction scale of the study group were higher than those of the control group (P＜0.05).The incidence of hypoglycemia in the study group was lower than that in the control group, the difference was statistically significant (P＜0.05).Conclusion The application of insulin pump in the treatment of SDM patients has good blood sugar control effect, and the dosage of insulin is small.It can effectively improve patients′ coordination degree, satisfaction and reduce the occurrence of hypoglycemia events.
2020 Vol. 27 (8): 194-196 [Abstract] ( 83 ) HTML (33 KB)  PDF  (0 KB)  ( 13 )
197 Application effect of hierarchical management in bedside wheelchair for patients with severe pneumonia in ICU
XU Zhen-hu； MAO Xiu-lian； LI Shi-peng； ZENG Wei-bo； CHEN Wen-ting； XIE Jia-xin
Objective To explore the application effect of hierarchical management in bedside wheelchair for severe pneumonia patients in ICU.Methods A total of 82 patients with severe pneumonia in our hospital from June 2017 to May 2018 were selected.According to the order of admission, the odd number of patients with severe pneumonia were treated as the experimental group, and the double number were the control group, 41 cases in each group.The experimental group was included in the study after using hierarchical classification criteria, the control group was included in the study after using nurses to evaluate their activity ability independently.The success rate of wheelchair, the effect of early exercise, the change of negative emotions and nursing satisfaction were observed in the two groups.Results The success rate of wheelchair in the experimental group was higher than that in the control group.The difference was statistically significant (χ2=5.51, P＜0.05).Barthel index score, quality of life scale (SAQ)-activity limitation score were compared with the control group at the time of transfer, there was no significant difference (P＞0.05).The Barthel index score and the SAQ-activity limitation score of the experimental group were higher than those of the control group at exit, and the differences were statistically significant (P＜0.05).The self-rating anxiety scale (SAS) score and self-rating depression scale (SDS) score of the experimental group compared with those of the control group at the time of transfer,there was no significant difference (P＞0.05).The SAS score and SDS score of the experimental group at exit were lower than those of the control group and the differences were statistically significant (P＜0.05).The total satisfaction of nursing in the experimental group was higher than that in the control group, the difference was statistically significant (χ2=3.90, P＜0.05).Conclusion The implementation of early activity programs such as bedside wheelchair can decrease the anxiety and depression of patients with severe pneumonia in ICU, and improve the early activity function of patients and raise the satisfaction of nursing, which is worth promoting.
2020 Vol. 27 (8): 197-199转209 [Abstract] ( 59 ) HTML (36 KB)  PDF  (0 KB)  ( 8 )
200 Application effect of bundled airway nursing in patients with mechanical ventilation after operation of hypertensive cerebral hemorrhage
LI Zhu-hua； WU Yu-bao； lIU Gui-xiang
Objective To explore the application effect of bundled airway nursing in patients with mechanical ventilation after hypertensive cerebral hemorrhage.Methods One hundred patients with mechanical ventilation after hypertensive intracerebral hemorrhage treated in our hospital from June 2017 to March 2019 were selected as research objects,they were divided into observation group (50 cases) and control group (50 cases) according to the different admission order.The observation group was given intensive airway nursing, while the control group was given routine nursing.The mechanical ventilation time, ICU stay time, anxiety and depression scores, and the total incidence of nursing adverse events were compared between the two groups.Results The mechanical ventilation time and ICU stay time in the observation group were shorter than those in the control group, the differences were statistically significant (P＜0.05).The scores of anxiety and depression in the observation group were lower than those in the control group, the differences were statistically significant (P＜0.05).The total incidence of nursing adverse events in the observation group was lower than that in the control group, the difference was statistically significant (P＜0.05).Conclusion After the operation of hypertensive intracerebral hemorrhage, the mechanical ventilation time and ICU stay time of the patients can be shortened, the negative emotions of the patients can be improved, and the risk of adverse events can be reduced.It is worthy of clinical application.
2020 Vol. 27 (8): 200-202 [Abstract] ( 67 ) HTML (31 KB)  PDF  (0 KB)  ( 15 )
203 Application of postoperative hierarchy of needs nursing in patients with ovarian cysts
FAN Zhi-jun； PENG You-qing； PENG Jun-lan； WANG Jin； CAI Jing-mei； WANG Zhi-hua； WANG Yu-ling
Objective To investigate the application of postoperative hierarchy of needs nursing in patients with ovarian cysts.Methods A total of 100 patients with ovarian cyst after operation in our hospital from January 2016 to May 2019 were selected as the study objects, they were divided into control group (50 cases) and observation group (50 cases) according to the method of random number table.Routine nursing was used in the control group, hierarchical nursing was used in the observation group.Postoperative recovery, self-care ability assessment scale (ESCA) score, total complication rate, nursing satisfaction score and quality of life score were compared between the two groups.Results The postoperative exhaust time, bedtime activity time, hospitalization time and diet recovery time of the observation group were shorter than those of the control group, the differences were statistically significant (P＜0.05).The ESCA score of the observation group was (114.63±16.21) points, which was higher than (106.05±14.85) points of the control group , the difference was statistically significant (P＜0.05).The total incidence rate of complications in the observation group was 6.00%, which was lower than 20.00% in the control group, the difference was statistically significant (P＜0.05).The nursing satisfaction score and quality of life score in the observation group were higher than those of the control group,the differences were statistically significant (P＜0.05).Conclusion The hierarchy of need nursing can shorten the patients′ postoperative exhaust time, bedtime, hospitalization time and diet recovery time, improve patients′ self-care ability, nursing satisfaction and quality of life, reduce the incidence of patients′ complications, which is worthy of clinical application.
2020 Vol. 27 (8): 203-205 [Abstract] ( 65 ) HTML (33 KB)  PDF  (0 KB)  ( 10 )
206 Effect of early warning safety mechanism on the prevention of adverse events of jaundice neonates with by blue light irradiation
LI Qun
Objective To explore the effect of early warning safety mechanism on the prevention of adverse events of jaundiceneonates with blue light irradiation.Methods A total of 166 children with jaundice in our hospital from December 2017 to December 2018 were selected and randomly divided into control group and observation group by sealed envelope method, 83 cases in each group.The control group was given routine neonatal nursing, while the observation group was given early warning safety mechanism intervention based on the above nursing basis.The clinical effect of the two groups after intervention was observed, and the nursing risks of the two groups were counted.The incidents occurred, and the nursing satisfaction of the family members of the two groups was investigated.Results The total effective rate of intervention in the observation group was 95.18%, higher than 84.34% in the control group, with statistical difference (P＜0.05); the total incidence of adverse nursing risk events in the observation group was 28.92%, lower than 89.16% in the control group, with statistical difference (P＜0.05); the nursing total satisfaction of the family members of the observation group was 96.39%, higher than 87.95% in the control group, the difference was statistically significant(P ＜0.05).Conclusion Early warning safety mechanism intervention can effectively improve the clinical efficacy of neonates with jaundice illuminated by blue light, and has a certain preventive effect on nursing adverse events.The nursing satisfaction of children′s family members is high.
2020 Vol. 27 (8): 206-209 [Abstract] ( 67 ) HTML (34 KB)  PDF  (0 KB)  ( 10 )
210 Influence of nurse patient communication skills on children′s treatment compliance
TAN Chun-miao
Objective To explore the effect of nurse-patient communication skills on pediatric treatment compliance.Methods A total of 100 pediatric inpatients admitted to our hospital from January 2018 to January 2019 were selected as research objects.They were divided into control group and observation group according to the random number table method, 50 cases in each group.Children in the control group were treated with conventional nursing methods, while children in the observation group were trained in communication skills of nurses on the basis of routine nursing, and the treatment compliance of children in the two groups was compared.Results The total score of compliance in the observation group was (4.1±0.7) point, which was higher than that in the control group (3.4±1.0) point, and the difference was statistically significant (P＜0.05).The disease awareness rate, one-time puncture success rate, compliance rate and satisfaction with nursing in the observation group were higher than those in the control group (P＜0.05).The quality of life score of the observation group was higher than that of the control group, the difference was statistically significant(P＜0.05).Conclusion The nursing staff and children through the good communication and communication can greatly help improve children with treatment compliance, more beneficial to the patients′ disease treatment, therefore, nursing staff should pay attention to their own requirements, improve the ability of communication with patients, especially should pay attention to strengthening and pediatric children communication skills.
2020 Vol. 27 (8): 210-212 [Abstract] ( 62 ) HTML (32 KB)  PDF  (0 KB)  ( 7 )
213 Application of quality control circle in reducing the incidence of urine leakage in patients with neurosurgical indwelling urethral catheters
GUO Xiao-li； ZENG Hong-jun； LI Li
Objective To explore the application of quality control circle in reducing the incidence of urine leakage in patients with neurosurgical indwelling urethral catheters.Methods The clinical data of 606 cases of indwelling urinary catheter patients admitted to our department from January to December 2018 were retrospectively analyzed, the current situation of urinary leakage was analyzed using quality control circle management.The countermeasures were formulated and implemented based on the main factors such as the excessively fast rinsing fluid flow rate, improper selection of the urinary tube, improper water injection in the airbag and urinary tube fixation methods.The results before and after improvement were compared and no results were analyzed.Results The incidence of urethral catheters after improvement was 10.2%, which was lower than 23.9% before improvement.Target compliance rate was 106.2%, and progress rate was 57.3%.Teamwork, professional knowledge, communication and coordination, activity confidence, responsibility honors and quality control circle techniques had all improved significantly.Conclusion Carrying out quality control circle activities can effectively reduce the occurrence of urine leakage from indwelling urethral catheter.
2020 Vol. 27 (8): 213-215转218 [Abstract] ( 52 ) HTML (33 KB)  PDF  (0 KB)  ( 7 )
216 Application effect of humanized nursing in the nursing of patients with chronic severe hepatitis B
LI Ting-ting
Objective To explore the application effect of humanized nursing in the nursing of patients with chronic severe hepatitis B.Methods Eighty cases of patients with chronic severe hepatitis B who were admitted to our hospital from January 2017 to November 2018 were selected and divided into control group and observation group according to random number table method, 40 cases in each group.The control group was given routine nursing, the observation group was given humanized nursing, respectively.The scores of adverse emotions, drug compliance and nursing satisfaction between two groups were compared.Results The scores of anxiety and depression after nursing in the observation group were lower than those in the control group (P＜0.05), and the total compliance rate and total satisfaction rate of nursing in the observation group were higher than those in the control group, the differences were statistically significant (P＜0.05).Conclusion Humanized nursing for chronic severe hepatitis B patients can alleviate their bad mood, improve their drug compliance, and make patients more satisfied with nursing services.
2020 Vol. 27 (8): 216-218 [Abstract] ( 68 ) HTML (29 KB)  PDF  (0 KB)  ( 9 )
219 Effect of early rehabilitation nursing intervention in neurology on the prognosis of hemiplegia due to ischemic stroke
YU Jia
Objective To explore the effect of early rehabilitation nursing intervention in neurology on the prognosis of hemiplegia due to ischemic stroke.Methods A total of 80 patients with ischemic stroke admitted in our hospital from November 2017 to March 2019 were selected as the research objects, they were divided into observation group (40 cases) and control group (40 cases) according to different nursing methods.The control group received routine nursing, the observation group received early rehabilitation nursing intervention.The total incidence rate of anxiety and depression,the European stroke scale (ESS) score, the modified Barthel Index (MBI) score before and after intervention and poor eating habits were compared between the two groups.Results The total incidence rate of anxiety and depression in the observation group was lower than that in the control group, the difference was statistically significant (P＜0.05).After intervention, the ESS score of the two groups was higher than before intervention, the ESS score of the observation group was higher than that of the control group, the differences were statistically significant (P＜0.05).After intervention, the MBI score of the two groups was higher than before intervention, the MBI score of the observation group was higher than that of the control group, the differences were statistically significant (P＜0.05).The incidence rates of smoking,drinking, high-fat diet and high-salt diet in the observation group were lower than those in the control group, the differences were statistically significant (P＜0.05).Conclusion Implementing early rehabilitation care for patients with ischemic stroke can alleviate the negative emotions of patients, improve the neurological function and activities of daily living, reduce the incidence rate of poor eating habits.
2020 Vol. 27 (8): 219-221转224 [Abstract] ( 66 ) HTML (34 KB)  PDF  (0 KB)  ( 8 )
222 Effect of full-time obstetrical nursing model on promoting breast feeding
MO Yu-jun； MO Xiao-mei； LIN Feng-mei
Objective To observe the effect of full-course nursing mode on promoting breastfeeding.Methods From January to October in 2018, 200 women who gave birth in our hospital were selected as study objects.The patients were divided into observation group (n=100) and control group (n=100) according to the principle of randomization.The observation group was given full-course nursing mode, the control group was given routine nursing.The knowledge of breastfeeding related to maternal feeding and the breastfeeding rate were comprehensively evaluated.Results After nursing, the observation group, the maternal scores on breastfeeding, milking, feeding skills, nutrition knowledge, breast care, etc.were higher than those of the control group with statistical differences (P＜0.05).The breastfeeding rates at 1,3, and 6 months after maternal nursing in the observation group were higher than those in the control group, and the differences were statistically significant (P ＜0.05).Conclusion The full-course nursing can enhance the maternal knowledge of breastfeeding and promote breastfeeding, which is worthy of promotion and application.
2020 Vol. 27 (8): 222-224 [Abstract] ( 65 ) HTML (31 KB)  PDF  (0 KB)  ( 11 )
225 Application of cardiopulmonary resuscitation targeted nursing in patients with acute myocardial infarction complicated with cardiac arrest
BAI Yan-mei
Objective To explore the application value of targeted nursing with cardiopulmonary resuscitation with acute myocardial infarction (AMI) complicated of cardiac arrest.Methods A total of 80 cases with cardiac arrest with AMI admitted to our hospital from February 2018 to May 2019 were selected as the research objects and divided into control group and observation group, 40 cases in each group.The observation group were implemented the nursing intervention for cardiopulmonary resuscitation, while the control group were received routine nursing, mainly including opening vein according to the doctor′s advice and implementing chest external cardiac compression.Then the changes of blood lactic acid level and myocardial enzyme level in the two groups during the intervention process (before, 30 min after and 6 h after the intervention) and 24 h after the intervention were compared, the occurrence of arrhythmia during cardiopulmonary resuscitation in the two groups was counted, and the recovery effect in the two groups was analyzed.Results 30 min and 6 h after the intervention, the blood lactic acid level in the observation group were lower than that of the control group, the difference was statistically significant (P＜0.05).24 h after the intervention, the lactic dehydrogenase (LDH) and creatine kinase isoenzyme (CK-MB) levels in myocardial enzyme indexes in the observation group were lower than those of the control group (P＜0.05).During cardiopulmonary resuscitation, the life-threatening arrhythmias in the observation group, such as ventricular fibrillation, ventricular tachycardia and atrioventricular block were lower than that of the control group (P＜0.05).The success rate of resuscitation in the observation group was higher than that of the control group, the difference was statistically significant (P＜0.05).Conclusion Targeted nursing intervention for patients with cardiac arrest after AMI can reduce the level of lactic acid, reduce the incidence of myocardial injury and complications, and improve the success rate.
2020 Vol. 27 (8): 225-227转231 [Abstract] ( 60 ) HTML (35 KB)  PDF  (0 KB)  ( 15 )
228 Influence of emotional nursing on negative emotions and self-behavior management of elderly patients with diabetic nephropathy treated by long-term hemodialysis
XIAO Li-ping； YANG Mu-lan
Objective To explore the effects of emotional nursing on negative emotions and self-behavior management of elderly patients with diabetic nephropathy (DN) treated by long-term hemodialysis.Methods Seventy elderly DN patients with long-term hemodialysis in our hospital from June 2016 to June 2018 were enrolled.The patients were divided into control group and observation group according to the random number table method, 35 cases in each group.The control group was given routine nursing, and the observation group was given emotional nursing.The depression,anxiety, self-behavior management score and quality of life diabetes specific quality of life (DSQL) were compared between the two groups before nursing and after 3 months of nursing.Results After 3 months of nursing, the scores of self-rating anxiety scale (SAS) and self-rating depression scale (SDS) in the two groups were lower than those before nursing (P＜0.05), and the SAS, SDS score in observation group were lower than those in control group, the differences were statistically significant (P＜0.05).The scores of self-behavioral management in the two groups were higher than those before nursing, and the score in observation group was higher than that in control group, the differences were statistically significant (P＜0.05).The scores of physiological dimension, psychological dimension, social relationship dimension and treatment dimension and total score of quality of life scale in the two groups were lower than those before nursing, and the scores in observation group were lower than those in control group, the differences were statistically significant (P＜0.05).Conclusion Emotional nursing can effectively improve the negative emotions and self-behavior management and promote the quality of life of elderly DN patients with long-term hemodialysis.
2020 Vol. 27 (8): 228-231 [Abstract] ( 65 ) HTML (35 KB)  PDF  (0 KB)  ( 11 )
232 Influence of Wechat software management on the recovery of hip function and self-nursing ability in the elderly
WEN Li-juan
Objective To explore the influence of Wechat software management on the recovery of hip function and self-care ability in the elderly.Methods A total of 66 elderly patients with femoral intertrochanteric fractures treated in our hospital from March 2016 to March 2019 were selected as the research objects.They were divided into the control group (33 cases) and the study group (33 cases) according to the random number table method.The control group was given routine nursing and discharge follow-up the control group, the study group was managed by Wechat software,and the patients in both groups were followed up for 3 months.The two groups of patients self-management ability,Harris hip score scale, self care ability scale (ADL) score and patient satisfaction between two groups were compared.Results The scores of the self-management ability of the study group were higher than those of the control group, and the difference was statistically significant (P＜0.05).There was no significant difference in the Harris score and ADL score between the two groups at discharge (P＞0.05).The Harris score and ADL score of the two groups at 3 months after discharge were higher than those at discharge (P＞0.05).The Harris and ADL score of the study group at 3 months after discharge was higher than that of the control group, and the difference was statistically significant (P＜0.05).Patients in the study group had higher satisfaction scores in all dimensions than that of the control group, and the differences were statistically significant (P＜0.05).Conclusion The application of Wechat software management in patients with femoral intertrochanteric fractures can improve self-management ability and self-care ability, promote the recovery of hip function of patients, and patients have higher satisfaction.
2020 Vol. 27 (8): 232-234 [Abstract] ( 61 ) HTML (32 KB)  PDF  (0 KB)  ( 10 )
235 Application effect of high quality nursing on diabetic foot patients
LIU Shuang
Objective To explore clinical effect of high quality nursing in patients with diabetic foot.Methods A total of 70 patients with diabetic foot who were admitted to the hospital from January 2017 to December 2018 were enrolled as study objects.They were divided into observation group (35 cases) and control group (35 cases) by random number table method.The control group was given routine nursing.On this basis, observation group was given high quality nursing.Both groups were nursed for 3 months.The disease knowledge level, adverse emotion (self-rating anxiety scale[SAS], self-rating depression scale [SDS]) and level of blood glucose (fasting blood glucose [FPG], postprandial 2 h blood glucose [2 h PG]) were compared between the two groups.Results The scores of mastery level to diabetic foot knowledge such as disease mechanism，diet control, exercise and daily nursing in observation group were higher than those in the control group (P＜0.05).After nursing, SAS and SDS in observation group were lower than those in control group (P＜0.05).The levels of FPG and 2 h PG in observation group were lower than those in the control group, the differences were statistically significant (P＜0.05).Conclusion The application of high quality nursing in patients with diabetic foot can improve their level of disease knowledge，and improve their adverse emotion, thus effectively controlling blood glucose.
2020 Vol. 27 (8): 235-237 [Abstract] ( 71 ) HTML (32 KB)  PDF  (0 KB)  ( 14 )
238 Application effect of systematic oral nursing in chronic periodontitis
GUO Xiao-yan; ZHENG Chun-mei; CUI Yan-ling
Objective To explore the application effect of systemic oral nursing in chronic periodontitis.Methods Ninety patients with chronic periodontitis who were admitted to our hospital from February 2018 to February 2019 were enrolled in the study.They were divided into control group and experimental group, 45 cases in each group.The control group received routine nursing management during the treatment period.The experimental group used systematic oral nursing, The nursing management quality and nursing satisfaction between the two groups were compared.Results The scores of quality of nursing management in the experimental group was higher than that in the control group, and the difference was statistically significant (P＜0.05).The total satisfaction of the patients in the experimental group was higher than that in the control group, and the difference was statistically significant (P＜0.05).Conclusion Systemic oral nursing for patients with chronic periodontitis can effectively promote disease rehabilitation and improve patient nursing satisfaction.The effect is significant and worth promoting.
2020 Vol. 27 (8): 238-240 [Abstract] ( 75 ) HTML (32 KB)  PDF  (0 KB)  ( 10 )
241 Effect of cardiac rehabilitation nursing management on quality of life and adverse cardiovascular events in patients after percutaneous coronary intervention
LENG Rong-rong
Objective To explore the application value of cardiac rehabilitation nursing management in patients after percutaneous coronary intervention (PCI).Methods From September 2017 to December 2018, 82 patients with PCI were selected and divided into control group and experimental group according to random number table method, 41 cases in each group.Routine nursing was carried out in the control group and cardiac rehabilitation nursing management was carried out in the experimental group.quality of life, incidence of adverse cardiovascular events and satisfaction between two groups were compared.Results There was no significant difference between the two groups before the intervention (P＞0.05); the scores of all dimensions of quality of life in the experimental group after 8 months of intervention were higher than those in the control group (P＜0.05); the total incidence of adverse vascular events in the experimental group (9.76%) was lower than that in the control group (39.02%), the difference was statistically significant (P＜0.05); the total satisfaction of the experimental group (95.12%) was higher than that of the control group (78.05%), the difference was statistically significant (P＜0.05).Conclusion Cardiac rehabilitation nursing management can improve the quality of life of patients after PCI, reduce the incidence of adverse vascular events, improve satisfaction, and effectively promote postoperative rehabilitation, which is worthy of application.
2020 Vol. 27 (8): 241-243 [Abstract] ( 62 ) HTML (31 KB)  PDF  (0 KB)  ( 9 )
244 Application of moxibustion combined with traditional Chinese medicine health education in nursing of patients with insomnia during menopause
DU Rong； JIANG Bing； LIU Si-li
Objective To explore the application value of moxibustion combined with TCM health education in the nursing of patients with insomnia during menopause.Methods A total of 118 patients with menopausal insomnia admitted to our hospital from April 2017 to April 2019 were enrolled in the study.They were divided into control group and research group according to random number table method, 59 cases in each group.The control group underwent routine nursing intervention.On the basis of this, the research group used moxibustion combined with traditional Chinese medicine health education for a period of 4 weeks.The psychological status, sleep quality and quality of life of the two groups were compared.Results There were no differences in the pre-treatment Hamiltonian depression scale (HAMD),Hamiltonian anxiety scale (HAMA), Pittsburgh sleep quality index (PSQI) and health survey profile (SF-36) scores (P＞0.05); the HAMD and HAMA scores of the study group were (9.54±3.16) and (10.49±2.96) points, which were lower than those of the control group (11.40±3.32) and (12.52±3.19) points，the differences were statistically significant (P＜0.05).The PSQI score of the study group was (7.45±3.18) points, lower than that of the control group (9.57±3.23)points, and the SF-36 scale was (84.89±9.42) points, which was higher than that of the control group (79.14±9.27)points, and the differences were statistically significant (P＜0.05).Conclusion Moxibustion combined with traditional Chinese medicine health education has high application value in the nursing of menopausal insomnia patients, which can improve patients′ bad mood and improve their sleep quality and quality of life.
2020 Vol. 27 (8): 244-246转250 [Abstract] ( 80 ) HTML (33 KB)  PDF  (0 KB)  ( 3 )
247 Application effect of early emotional nursing model in elderly patients with glioma after operation
YU Xue
Objective To investigate the application effect of early emotional nursing model in elderly patients with glioma after surgery.Methods A total of 73 patients with glioma surgery from January 1, 2018 to February 1, 2019 were selected as the research objects, all the patients were divided into experimental group (37 cases) and control group(36 cases) according to the random number table method.The experimental group adopted early emotional nursing method, and the control group adopted conventional nursing method.The self-care ability, stress response before and after nursing, and compliance with nursing intervention were compared between the two groups.Results The scores of Zung′s anxiety scale (SAS) and Zung′s depression scale (SDS) in the experimental group after nursing were lower than those in the control group, and the differences were statistically significant (P＜0.05).The exercise of self-care agency scale (ESCA) score of the experimental group after nursing was higher than that of the control group, and the difference was statistically significant (P＜0.05).The total compliance of patients in the experimental group was higher than that in the control group, and the difference was statistically significant (P＜0.05).Conclusion Early emotional nursing intervention has definite effect on postoperative stress response of glioma patients after operation, which can effectively relieve adverse stress, improve the self-care ability of patients, and also improve the compliance of patients.It is worthy of clinical application.
2020 Vol. 27 (8): 247-250 [Abstract] ( 63 ) HTML (34 KB)  PDF  (0 KB)  ( 11 )
251 Application value analysis of systematic nursing intervention during continuous blood purification treatment for severe pancreatitis
LIU Yan； ZHENG Qing-xia
Objective To explore the application value of systematic nursing intervention in severe pancreatitis during continuous blood purification therapy.Methods A total of 100 patients with severe pancreatitis treated in our hospital from January 2016 to December 2018 with continuous blood purification therapy were selected as the subjects.They were divided into observation group and control group according to random number table method, 50 patients in each group.The patients in control group were given routine clinical nursing and the patients in observation group were intervened by systematic nursing.The incidence of complications, the improvement of symptoms and the changes of physical signs were compared between the two groups.Results The body temperature, respiratory rate, heart rate, serum amylase value and the total incidence of complications and APACHEⅡscores in the observation group were lower than those in the control group, and the blood oxygen saturation was higher than that in the control group, the differences were statistically significant (P＜0.05).Conclusion The use of systematic nursing intervention in the treatment of severe pancreatitis with continuous blood purification can significantly improve the symptoms and signs of the patients and reduce the incidence of complications.It has great clinical application and promotion value.
2020 Vol. 27 (8): 251-253 [Abstract] ( 66 ) HTML (34 KB)  PDF  (0 KB)  ( 9 )
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