中国当代医药
Home
中文
中国当代医药
Forthcoming Articles
Current Issue
Archive
Advanced Search
Read Articles
Download Articles
Email Alert
Quick Search
Adv Search
2019 Vol. 26, No. 3
Published: 2019-01-28
4
Influence of Nonylphenol on ovary and serum estradiol and progesterone level in mice
MI Xue;HAN Ping;CAO Yan-hua;DING Xiao;WANG Hui;HE Yan-fang
Objective
To study the influence of Nonylphenol(NP)poisoning by intragastric administration on ovary,estrogen(E
2
)and progesterone(P)level in Kunming mice,in order to evaluate the reproductive and developmental toxicity of NP.
Methods
Thirty healthy SPF female mice of Kunming were randomly divided into the control group(corn oil)and 25,100 mg/kg NP group,there were 10 mice in each group.Gastric administration was used for poisoning,the contamination capacity was 0.1 ml/10 g,once a day,5 days a week,12 weeks in a row.Serum E
2
,P and FSH were measured and ovarian histopathological sections were observed.
Results
There was no significant difference in serum E
2
,P and FSH between the 25 mg/kg NP group and the control group(P＞0.05),and the number of primary follicles and mature follicles in ovarian histopathological sections of 25 mg/kg NP group and control group was significantly different(P＜0.05).The level of E
2
,P and FSH in serum and the number of primary follicles and mature follicles in pathological sections of ovary between 100 mg/kg NP group and control group,25 mg/kg NP group were significantly different(P＜0.05),and the primary follicles atrophied,the granulosa cells of ovary loosened,the nucleus of oocyte condensed,and the follicular cavity became smaller in 100 mg/kg NP group.
Conclusion
Increased dose of NP can cause damage to ovarian function in mice having reproductive toxicity and developmental toxicity.
2019 Vol. 26 (3): 4-6-15 [
Abstract
] (
107
)
HTML
(43 KB)
PDF
(0 KB) (
14
)
7
Meta-analysis of FLT3-TKD gene mutation on the prognosis of acute myeloid leukemia
DAI Wei1WANG Yan2NONG Wei-xia2PAN Xin2LONG Zhen-zhu-ma2ZHANG Da-qian2ZHANG Hong-xia2 WU Guang-sheng2▲
Objective
To evaluate the influence of FLT3-TKD mutation on the prognosis of acute myeloid leukemia(AML)using meta-analysis.
Methods
“FLT3-TKD”,“D835” and “Acute Myeloid Leukemia” as English terms were searched in Pubmed.“FLT3-TKD”,“D835” and “Jixing Suixi Baixuebing” (in Chinese characters;acute myeloid leukemia)were searched in China National Knowledge Infrastructure and Wanfang database.The retrieval time was from the inception to April 14,2018.
Results
Eight articles were included,and 7 in English-version and 1 in Chinese,with a total of 3430 patients.Meta-analysis showed that there were no statistical differences in a complete response rate(CR)(HR=1.06,95%CI 0.99-1.14,P=0.07)and disease-free survival(DFS)(HR=1.44,95%CI=0.99-2.09,P=0.06).The overall survival rate(OS)(HR=1.37,95%CI=1.12-1.67,P=0.002)was displayed a statistical difference between the two groups.
Conclusion
FLT3-TKD gene mutation may be a risk factor for poor prognosis in patients with AML.
2019 Vol. 26 (3): 7-11 [
Abstract
] (
125
)
HTML
(44 KB)
PDF
(0 KB) (
15
)
12
Relationship of homocysteine and MTHFR C677T gene polymorphism with morning blood pressure surge
LI Rong1,2WANG Fang2LIAN Zhe-xun1▲
Objective
To explore the relationship between plasma homocysteine(Hcy)and methylenetetrahydrofolate reductase(MTHFR)gene polymorphisms with morning blood pressure surge(MBPS).
Methods
A total of 122 patients with essential hypertension diagnosed and treated in our hospital from November 2015 to December 2016 were selected.According to 24 ambulatory blood pressuremonitoring(ABPM)results,the difference between morning systolic blood pressure and night sleep systolic blood pressure was less than 35 mmHg (1 mmHg=0.133 ka),the control group (n=52)had no MBPS phenomenon,and the observation group(n=70)had MBPS phenomenon.All subjects were tested with blood from the anterior elbow vein on an empty stomach in the morning,and the level of urinary microalbumin,serum uric acid,serum creatinine and blood urea nitrogen were detected by automatic biochemical analyzer.The level of plasma Hcy was detected by circulating enzyme method and MTHFR C677T genotype was detected by PCR fluorescence method.The relationship between the level of plasma Hcy and the distribution of MTHFR C677T genotype with morning peak blood pressure was observed.
Results
The Hcy level of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).The TT frequency of MTHFR C677T genotype in observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).The plasma Hcy level of TT genotype in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).Logistic regression analysis showed that Hcy level was a risk factor for the occurrence of MBPS(P＜0.05).The genotype of MTHFR 677 TT was a risk factor for the occurrence of MBPS(P＜0.05).
Conclusion
Hcy level and MTHFR 677TT genotype were closely related to MBPS,and the pure and mutation of MTHFRC 677T results in the increase of Hcy level,which indirectly participates in the formation of MBPS.
2019 Vol. 26 (3): 12-15 [
Abstract
] (
114
)
HTML
(37 KB)
PDF
(0 KB) (
13
)
16
Research progress of pathogenesis of anti-neutrophil cytoplasmic antibodies associated vasculitis
FAN Ming-hua1,2XING Guang-qun2▲
Anti-neutrophil cytoplasmic antibodies(ANCA)-associated vasculitides (AAV)are systemic autoimmune diseases characterised by inflammation of small blood vessels.The pathogenesis of AAV is complex and remains incompletely understood.Recent advances have been made in the understanding of the pathogenesis of these diseases,including the pathogenic role of ANCA,neutrophil extracellular traps(NETs)and neutrophils as mediators of injury,dysregulation of the complement system,and the role of T cells.The aim of this review is to summarise current information and recent advances in understanding the pathogenesis of AAV.
2019 Vol. 26 (3): 16-18 [
Abstract
] (
117
)
HTML
(32 KB)
PDF
(0 KB) (
18
)
19
Current status of assessment and pain management in special populations
ZHANG Wan-yingWANG Jun▲
Pain is one of the most common symptoms in the clinic.Scientific pain management can reduce the negative effects of pain,and pain assessment is the first step in the pain management.In China,the pain management of special populations is relatively weak,and the main reasons include the neglect of pain in special population by medical staff,the low level of nurses′knowledge of pain management in special population,and the nurses′inadequate grasp of the choice and application of pain assessment tools.This article reviews the current status of pain management and assessment in special populations from the above three aspects,in order to give medical staff a special attention to the pain management of special patients and provide a scientific basis for clinical nurses to accurately assess the pain of special patients,reduce patient suffering and improve pain management.
2019 Vol. 26 (3): 19-21转24 [
Abstract
] (
101
)
HTML
(40 KB)
PDF
(0 KB) (
13
)
22
Clinical effect of Alginate dressing combined with He Ne-laser in the treatment of incision fat liquefaction
DENG Zuo-meiLIU Hua-zhiWU Lian-xiang▲ DUAN Zhen-qiLIU Yue-quan ZHANG Feng-ying
Objective
To investigate the efect of Alginate dressing combined with He-Ne laser in the treatment of incision fat liquefaction.
Methods
A total of 40 patients with abdominal incision fat liquefaction from January 2015 to April 2018 in our hospital were selected as the subjects.According to the random number table method,they were randomly divided into experimental group and control group,with 20 cases in each group.The experimental group was treated with Alginate dressing combined with He-Ne laser irradiation,while the control group was treated with traditional dry dressing change combined with He-Ne laser irradiation.The healing time of the two groups was compared and analyzed.
Results
All the incisions with fat liquefaction completely healed.The wound healing time of the experimental group was(8.23±1.05)d,which was shorter than that of the control group for(11.92±1.24)d,and the difference was statistically significant(P＜0.05).
Conclusion
Alginate dressing combined with He-Ne laser irradiation in the treatment of abdominal incision fat liquefaction can accelerate the healing of incision fat liquefaction,shorten the time of wound treatment,with clinical popularization value.
2019 Vol. 26 (3): 22-24 [
Abstract
] (
90
)
HTML
(28 KB)
PDF
(0 KB) (
8
)
25
Clinical effect of noninvasive positive pressure ventilation in the treatment of chronic obstructive pulmonary disease with respiratory failure
HUANG Zhi-wei1LIN Jie2ZHOU Yu-fei1
Objective
To analyze the clinical effect of noninvasive positive pressure ventilation (NIPPV)in the treatment of chronic obstructive pulmonary disease (COPD)with respiratory failure (RF).
Methods
A total of 120 patients with COPD and RF admitted to our hospital from September 2016 to December 2017 were selected as study subjects.They were randomly divided into observation group and control group,with 60 cases in each group.In the control group,conventional regimen was used,while in the observation group,NIPPV was added on the basis of conventional treatment.The clinical efficacy of the two groups were compared.
Results
The total effective rate of the observation group was significantly higher than that of the control group,with a significant difference (P＜0.05).There was no significant difference in PaO
2
,PaCO
2
,respiratory rate or heart rate between the two groups before treatment(P＞0.05).After treatment,the PaO
2
of the observation group was significantly higher than that of the control group.The PaCO
2
,respiratory rate,and heart rate were significantly lower than those of the control group,with statistical differences (P＜0.05).At the same time,the quality of life scores of the observation group were higher than those of the control group.The hospital stay was significantly shorter than that of the control group,with a significant difference (P＜0.05).
Conclusion
For patients with COPD and RF,NIPPV can obtain a satisfactory effect.It can effectively improve the relevant indicators of patients as well as the quality of life,and ensure patient′s health.
2019 Vol. 26 (3): 25-27 [
Abstract
] (
116
)
HTML
(37 KB)
PDF
(0 KB) (
19
)
28
Clinical effect of traditional Chinese medicine for patients with secondary gastrointestinal dysfunction after control of upper gastrointestinal bleeding
TAN Qi-jia
Objective
To study and determine the clinical effects of traditional Chinese medicine for patients with secondary gastrointestinal dysfunction after control of upper gastrointestinal bleeding.
Methods
One hundred cases of patients with secondary gastrointestinal dysfunction after control of upper gastrointestinal bleeding treated in our hospital from March 2016 to February 2017 were selected as the subjects,and divided into control group and study group,with 50 cases in each group.The control group was given conventional western medicine treatment,and the study group was given traditional Chinese medicine treatment on the basis of control group.The frequency of defecation,number of bowel wheezing,intra-abdominal pressure,gastrointestinal function score and incidence of multiple organ dysfunction syndrome(MODS)were compared between the two groups before and after treatment.
Results
There were no significant differences in the frequency of defecation,number of bowel wheezing,intra-abdominal pressure and gastrointestinal function scores between the two groups before treatment(P＞0.05).The frequency of defecation and number of bowel wheezing in the study group were more than those in the control group afte 3 and 7 days treatment,and the differences were statistically significant(P＜0.05).The intra-abdominal pressure and gastrointestinal function scores in the study group were higher than those in the control group afte 7 days treatment,and the differences were statistically significant(P＜0.05).The incidence of MODS in the study group was lower than that in the control group,and the difference was statistically significant(P＜0.05).
Conclusion
The clinical effect of traditional Chinese medicine for patients with secondary gastrointestinal dysfunction after control of upper gastrointestinal bleeding is significant.It can restore gastrointestinal function and reduce the incidence of complications.It is worthy of promotion in clinical practice.
2019 Vol. 26 (3): 28-30 [
Abstract
] (
97
)
HTML
(35 KB)
PDF
(0 KB) (
15
)
31
Clinical effect of different target pulse radiofrequency in the treatment of post-herpetic neuralgia in elderly patients with thoracolumbar
ZHU Chun-huiWANG Zhe-yin LIN Di-yang
Objective
To investigate the clinical effect of radiofrequency ablation of the dorsal root ganglion(DRG)and radiofrequency ablation of the anterior and posterior branches of the spinal nerve in the treatment of post-herpetic neuralgia in the elderly.
Methods
A total of 60 elderly patients with chest and back herpes zoster neuralgia treated in our hospital from January 2017 to January 2018 were selected as the subjects,and divided into DRG group (n=30)and spinal nerve group (n=30)according to randomized controlled grouping method.The DRG group was treated with DRG pulse radiofrequency.The spinal nerve group was treated with radiofrequency signals of the anterior and posterior branches of the spinal nerve.After 6 months of follow-up after discharge.The differences between visual analog scale(VAS)and analgesic use before and after treatment were compared.The quality of life indicators before and after treatment and the incidence of adverse reactions during treatment were compared.
Results
The improvement rate of the DRG group was significantly higher than that of the spinal nerve group (P＜0.05).The VAS scores of the DRG group were significantly lower than those of the spinal nerve group after the first treatment,the third treatment,1 month,3 months of post-treatmen (P＜0.05).The use rate of tramadol in the DRG group was significantly lower than that in the spinal nerve group at different time points(P＜0.05).The PSQI,anxiety score and depression scores of the DRG group were significantly lower than those of the spinal nerve group at 1,3,6 months after discharge,and SF-36 scores were significantly higher than those of the spinal nerve group (P＜0.05).There were no adverse reactions in the two groups(P＞0.05).
Conclusion
DRG pulse radiofrequency can effectively alleviate post-herpetic neuralgia in the elderly,and improve the quality of life of patients after treatment.
2019 Vol. 26 (3): 31-34 [
Abstract
] (
93
)
HTML
(39 KB)
PDF
(0 KB) (
12
)
35
Effect of Xingnaojing combined with Nalmefene Hydrochloride in the treatment of coma patients with acute alcohol intoxication
LI Ai-lian LIANG Mao-jin ZHANG Sen LIANG Jian-wen LIANG Jie-pei
Objective
To study the effect of Xingnaojing combined with Nalmefene Hydrochloride in the treatment of coma patients with acute alcohol intoxication.
Methods
A total of 82 cases of patients with acute alcohol intoxication in coma treated in our hospital from July 2017 to May 2018 were selected as the subjects,and randomly divided into control group(41 cases)and experimental group(41 cases).The group was only treated with Nalmefene Hydrochloride,and the experimental group was treated with Xingnaojing combined with Nalmefene Hydrochloride.The clinical treatment effect,symptom recovery time and oxidative stress response were compared between the two groups.
Results
The total effective rate of the experimental group was 95.12%,which was higher than that of the control group(80.49%)(P＜0.05).The conscious time and disappearance time of the experimental group were shorter than those of the control group(P＜0.05).After the medication,the MDA level of the two groups decreased,and the SOD level increased,and the MDA in the experimental group was lower than that in the control group,SOD in the experimental group was higher than that in the control group(P＜0.05).
Conclusion
The clinical treatment effect of xingnaojing combined with naomefen hydrochloride in the treatment of acute alcohol intoxication coma is definite,which significantly shortens the patients′mental sobriety and symptom disappearance time,reduces the oxidative stress reaction,and is worthy of clinical promotion.
2019 Vol. 26 (3): 35-37 [
Abstract
] (
116
)
HTML
(33 KB)
PDF
(0 KB) (
16
)
38
Analysis of risk factors for prognosis of patients with Acinetobacter baumannii infection in ICU of our hospital
LIU Hong-shuan ZHANG Qing CAI Yang-ping
Objective
To analyze the risk factors of prognosis in patients with Acinetobacter baumannii infection in our intensive care unit(ICU).
Methods
A retrospective analysis of 158 cases clinical data of patients with Acinetobacter baumannii infection in the ICU of our hospital from January 2014 to December 2017 was conducted.The patients were divided into survival group and death group according to the 28-day prognosis.The univariate analysis(chi-square test and t test)and multivariate logistic regression analysis were used to calculate the odds ratio(OR)value with 95% confidential interval(CI),and to determine the relevant risk factors for the prognosis of infected patients.
Results
The source of Acinetobacter baumannii infection strains in our ICU were mainly from sputum of lower respiratory tract accounting for 91.8%.In these infected patients,the mechanical ventilation rate was 72.8%,the usage of multiple antibiotics was 44.9%,and the drug resistance rate was 65.2%.The univariate analysis showed that multiple antibiotics usage and drug resistance of strains were risk factors for death in patients with Acinetobacter baumannii infection.Multivariate Logistic regression analysis also displayed that the above-mentioned two factors were the prognostic ones leading to death of patients with Acinetobacter baumannii infection.
Conclusion
The patients with Acinetobacter baumannii infection in our hospital characterized advanced age,high mechanical ventilation rate,high antibiotic use rate,and serious drug resistance of strains.It found that the use of multiple antibiotics and drug resistance of strains are risk factors and prognostic factors for death in patients with Acinetobacter baumannii infection.Clinical measures of strengthening infection control,cutting off the route of transmission of Acinetobacter baumannii,intensifying the clinical management of antibacterial drugs,adjusting the antibiotics regimen according to PK/PD,and reducing the resistance of Acinetobacter baumannii should be taken in order to strengthen the prevention and control of Acinetobacter baumannii infection and improve prognosis in infected patients.
2019 Vol. 26 (3): 38-40 [
Abstract
] (
91
)
HTML
(32 KB)
PDF
(0 KB) (
14
)
41
Comparison of the application effects of magnesium sulfate and compound polyethylene glycol electrolyte in colonoscopy for intestinal preparation
OUYANG Sheng1WANG Hong2
Objective
To analyze the application effect of magnesium sulfate and compound polyethylene glycol electrolyte in colonoscopy for intestinal preparation.
Methods
A total of 500 patients who underwent colonoscopy in our hospital from March 2016 to February 2018 were selected as the subjects,and divided into the observation group and the control group,with 250 cases in each group.The group was treated with oral compound polyethylene glycol electrolyte,and the control group was treated with oral magnesium sulfate.The adverse reactions (abdominal distension,nausea and vomiting and diarrhea),the gut preparation cleanliness rate,and patients′satisfaction were compared between the two groups.
Results
The total incidence of adverse reactions in the observation group(1.20%)was lower than that in the control group(12.00%)(P＜0.05).The gut preparation cleanliness rate in the observation group(96.00%)was higher than that in the control group (60.00%)(P＜0.05).The patients′total satisfaction rate in the observation group(98.40%)was higher than in the control group(64.00%)(P＜0.05).
Conclusion
In the colon preparation of colonoscopy,the effect of compound polyethylene glycol electrolyte dispersion is better than that of magnesium sulfate.
2019 Vol. 26 (3): 41-43 [
Abstract
] (
94
)
HTML
(33 KB)
PDF
(0 KB) (
20
)
44
Influence of high-volume continuous renal replacement therapy on PCT,TNF-α,IL-6,and IL-8 in patients with pancreatitis complicated with acute renal failure
LIU Chang-bo LI Mu
Objective
To investigate the influence of high-volume continuous renal replacement therapy (HV-CRRT)on procalcitonin(PCT),tumor necrosis factor-α (TNF-α),IL-6,and IL-8 in acute pancreatitis complicated with acute renal failure.
Methods
Eighty-six patients with acute pancreatitis complicated with acute renal failure who treated by continuous veno-venous hemofiltration (CVVH)in our hospital from September 2014 to September 2017 were selected as the subjects,and divided into two groups by different ultrafiltration rate,with 43 cases in each group.The patients in the control group treated by the normal capacity model with a ultrafiltration rate was 20 ml/(kg·h),and the observation group treated by the HV-CVVH model with a ultrafiltration rate was 35 ml/(kg·h).The levels of PCT,TNF-α,IL-6,and IL-8 in serum were measured by ELISA before and at 2,6,12 h after treatment,and 12 h after CVVH.
Results
The serum PCT,TNF-α,IL-6 and IL-8 levels in the two groups were decreased at 2 h after treatment.The lowest levels appeared at 6 h after treatment,and the PCT,TNF-α,IL-6 and IL-8 levels in the observation group were lower than those in the control group after treatment(P＜0.05).
Conclusion
HV-CRRT can more effectively remove various inflammatory factors and reduce the levels of serum PCT for the treatment of pancreatitis complicated by acute renal failure.Additionally,replacement of the blood filter at appropriate time-points can improve the treatment effect．
2019 Vol. 26 (3): 44-46转50 [
Abstract
] (
102
)
HTML
(34 KB)
PDF
(0 KB) (
15
)
47
Comparison of clinical effects of Methotrexate combined with Tacrolimus and Methotrexate combined with Ilalimide in the treatment of refractory rheumatoid arthritis
CHEN Jin-ji1LIANG Hui-lian2YANG Li-ping3
Objective
To investigate and compare the clinical effects of Methotrexate(MTX)combined with Tacrolimus(TAC)or Ilalimide(IT)in the treatment of refractory rheumatoid arthritis(RRA).
Methods
A total of 92 patients with RRA admitted to our hospital from September 2015 to June 2018 were selected as the subjects,and randomly divided into observation group and control group,with 46 cases in each group.Patients in the control group were treated with MTX plus TAC,and patients in the observation group were given MTX plus IT.The clinical efficacy of the patients of the two groups,the joint pain index before and after treatment,the joint swelling index,the morning stiffness time and the VAS scores,and the incidence of adverse drug reactions were analyzed and compared.
Results
The total remission rate of the observation group was higher than that of the control group (P＜0.05).The postoperative pain index,joint swelling index and VAS scores of the observation group were lower than those of the control group,and morning stiffness time in the observation group was shorter than that in the control group (P＜0.05).There was no significant difference in the total incidence of complications between the two groups(P＞0.05).
Conclusion
MTX combined with IT in the treatment of RRA is superior to tacrolimus combined with TAC in improving patients′clinical symptoms and improving curative effect,and the safety of the two treatments is equivalent.
2019 Vol. 26 (3): 47-50 [
Abstract
] (
123
)
HTML
(34 KB)
PDF
(0 KB) (
12
)
51
Application effect of UE video laryngoscope combined with adjustable tracheal tube in general anesthesia intubation
DONG Fa-xian ZHENG De-zhiZHANG Yong-xin LI Xian-liKUANG Kun-he ZHONG Sen-xing
Objective
To explore the application effect of UE video laryngoscope combined with adjustable tracheal tube in general anesthesia.
Methods
A total of 121 patients with general anesthesia for tracheal intubation from June 2017 to July 2018 in our hospital were selected as the research objects.They were divided into the study group (n=61)and the control group (n=60)according to random number table method.The control group was treated with direct laryngoscope combined with common tracheal tube for tracheal intubation.The study group was treated with UE video laryngoscope combined with adjustable tracheal tube for tracheal intubation.The changes of hemodynamic parameters(including systolic blood pressure,diastolic blood pressure,heart rate,etc.)before and immediately after induction of anesthesia,glottic exposure time,tracheal intubation time,success rate of primary intubation,mis-intubation rate and incidence of complications were compared between the two groups.
Results
Before induction of anesthesia,there was no significant difference in systolic blood pressure,diastolic blood pressure and heart rate between the two groups (P＞0.05).Immediately after intubation,the systolic blood pressure,diastolic blood pressure and heart rate of the study group were lower than those of the control group,the difference was statistically significant(P＜0.05).There was no significant difference in the level of hemodynamics in the study group between immediately after intubation and the anesthesia before induction (P＞0.05).The level of hemodynamics immediately after intubation in the control group were higher than those in the anesthesia before induction,and the difference was statistically significant(P＜0.05).The glottic exposure time and tracheal intubation time of the study group were shorter than those of the control group,the success rate of one intubation in the study group was higher than that in the control group,with significant difference(P＜0.05).The total postoperative complication rate and misinterpretation rate of the study group were lower than those of the control group,with significant difference (P＜0.05).
Conclusion
In patients with general anesthesia tracheal intubation,the use of UE video laryngoscope combined with adjustable tracheal tube for tracheal intubation can not only ensure the success rate of patient intubation,but also shorten the time of tracheal intubation,reduce the influence of tracheal intubation on hemodynamics and reduce the incidence of complications after operation.
2019 Vol. 26 (3): 51-54 [
Abstract
] (
103
)
HTML
(38 KB)
PDF
(0 KB) (
14
)
55
Application value of low-dose epidural anesthesia with Fentanyl and Tetracaine Jelly in percutaneous nephrolithotripsy
YING Chao
Objective
To investigate the application value of low-dose epidural anesthesia with Fentanyl and Tetracaine Jelly in the percutaneous nephrolithotripsy.
Methods
A total of 152 patients who underwent percutaneous nephrolithotripsy in our hospital from October 2016 to October 2017 were enrolled.The patients were divided into the single group (n=76)and tha combined group (n=76)according to a double-blind digital table method.In the single group,epidural anesthesia alone was used,and in the combined group,a small dose of epidural anesthesia with Fentanyl and Tetracaine Jelly was adopted.The occurrence of bradycardia and hypotension,and haemodynamics indexes including mean arterial pressure(MAP),saturation of pulse oximetry(SpO
2
),and heart rate(HR)at different time points including before anesthesia,placement of ureteral catheter,5-min lithotripsy,and 20-min lithotripsy were compared in the two groups.
Results
There was no significant difference in the incidence of bradycardia and hypotension between the two groups (P＞0.05).There was no significant in SpO
2
before anesthesia,at placement of ureteral catheter,5-min lithotripsy,and 20-min lithotripsy in the two groups(P＞0.05).There was no significant difference in MAP and HR between the two groups before anesthesia (P＞0.05).While during the ureteral catheter placement,at 5-min lithotripsy,and 20-min lithotripsy in the combined group,both MAP and HR were lower than those in the single group,with statistical significance (P＜0.05).
Conclusion
In percutaneous nephrolithotripsy,Fentanyl combined with Tetracaine Jelly at a low-dose epidural anesthesia can reduce the impact on hemodynamic stability of patients.It is safe and worthy of promotion and application in clinic.
2019 Vol. 26 (3): 55-57 [
Abstract
] (
106
)
HTML
(31 KB)
PDF
(0 KB) (
11
)
58
Application effects of Propofol combined with Remifentanil in pediatric anesthesia
ZHANG Xiao-hua
Objective
To compare the effects of Propofol combined with Remifentanil and Propofol combined with Sevoflurane in pediatric anesthesia.
Methods
A total of 118 patients who had taken the surgical treatment in our hospital from September 2014 to November 2016 were selected and divided into the observation group (59 cases)and the control group(59 cases).The observation group was anesthetized by Propofol combined with Remifentanyl,and the control group was anesthetized by Propofol combined with Sevoflurane.The anesthesia effects was compared between the two groups.
Results
After the surgery,the anesthesia induction time,the breathing recovery time,extubation time and the consciousness recovery time in the observation group were significantly shorter than those in the control group,and the difference was statistically significant(P＜0.05).The total incidence of adverse reactions in the observation group was 11.86%,which was lower than 27.12%in the control group,and the difference was statistically significant(P＜0.05).
Conclusion
In pediatric surgical anesthesia,Propofol combined with Remifentanil has a good anesthetic effect and is worthy of popularization and application.
2019 Vol. 26 (3): 58-60 [
Abstract
] (
87
)
HTML
(31 KB)
PDF
(0 KB) (
19
)
61
Application effect of different analgesic modes in elderly patients after hip surgery
Objective
To explore the clinical effect of different analgesic modes in elderly patients after hip surgery.
Methods
A total of 100 elderly patients who were accepted hip surgery in our hospital from January 2014 to June 2018 were selected as study subjects and divided into the control group and the observation group according to different analgesic patterns,with 50 cases in each group.Patients in the control group were treated with intravenous analgesia pump(included Sufentanil,Tropisetron Hydrochloride and Saline),and those in the observation group were treated with Parecoxib intravenously.The pain VAS scores,postoperative analgesic satisfaction and the incidence rate of adverse reaction were observed and compared between the two groups.
Results
The VAS scores of the observation group at 2,12,24 h after surgery were significantly lower than those of the control group(P＜0.05).The total satisfaction rate of the observation group was 94.00%,which was significantly higher than that in the control group(80.00%)(P＜0.05).There was no statistical difference in the total incidence rate of adverse reaction between the two groups(P＞0.05).
Conclusion
Parecoxib has obvious curative effect on postoperative analgesia in elderly patients with hip surgery.It can improve the patients′satisfaction while reduce the rate of adverse reactions.It is benefic to promote postoperative physical recovery and functional exercise.It is worthy of clinical promotion and application.
2019 Vol. 26 (3): 61-63 [
Abstract
] (
108
)
HTML
(34 KB)
PDF
(0 KB) (
14
)
64
Application effect of different doses of Butorphanol on epidural labor analgesia
BI Lin HU Ding-hao HUANG Qing-fang ZHU Rui
Objective
To explore the application effect of different doses of Butofenol in epidural labor analgesia.
Methods
A total of 520 single and full-term parturients admitted from March to October in 2017 in our hospital were selected as subjects,and they were divided into group A (130 cases),group B (130 cases),group C (130 cases)and group D (130 cases)according to the random sampling method.All the three groups received different doses of Butopenol for epidural labor analgesia,except group D,which did not receive labor analgesia treatment.The analgesic effect and the incidence of adverse reactions were compared between the four groups.
Results
The analgesic effect of the intervention of group A,B and C was higher than that of group D,and the difference was statistically significant(P＜0.05).The level of PCO
2
in group A,B and D was lower than that in group C,and the level of PO
2
in group A,B and C was higher than that in group D,the difference was statistically significant(P＜0.05).There was no significant difference in pH value and BE value between the four groups(P＞0.05).Compared with group D,the Apgar score of neonates in group A,B and C showed no statistical significance(P＞0.05).Compared with group D,Apgar score in group A,B and C showed no statistical significance(P＞0.05).The total incidence rate of maternal adverse reactions in group A,B,C and D was 1.54%,6.92%,11.54%and 30.00%,respectively,the total incidence rate of maternal adverse reactions in group D was higher than that in group A,B and C,with statistically significant differences(P＜0.05).
Conclusion
Different doses of Butofenol can play a higher analgesic effect in the use of maternal labor analgesia,and the safety is higher,the incidence of adverse reactions after parturition is less,and the impact on the newborn is low,which is worthy of widely recommended clinical application.
2019 Vol. 26 (3): 64-66 [
Abstract
] (
109
)
HTML
(35 KB)
PDF
(0 KB) (
14
)
67
Influence of lung protective ventilation strategy on elderly patients on perioperative arterial oxygenation and the post anesthesia care unit resident time after retroperitoneal laparoscopic radical prostatectomy
JIANG Jin-diHE Ming-feng XU Yu-jie▲
Objective
To explore the influence of lung protective ventilation in elderly patients on lung compliance and oxygenation after retroperitoneal laparoscopic radical prostatectomy.
Methods
A total of 50 patients underwent selective laparoscopic radical prostatectomy from June 2017 to March 2018 in our hospital were selected and divided into group A and group B according to the random number table method,25 cases in each group.Lung protection ventilation was used in group A,and conventional ventilation was used in group B.Perioperative arterial oxygenation at induction(T
0
),30 min during operation(T
1
),60 min during operation(T
2
),90 min during operation(T
3
),30 min after deoxidation were compared between the two groups.The post anesthesia care unit(PACU)resident time,and the incidence of pulmonary complications and subcutaneous emphysema were recorded in the two groups.
Results
The PACU time of group A was shorter than that of group B,the difference was statistically significant(P＜0.05).The total incidence rate of complication of group A was lower than that of group B,the difference was statistically significant(P＜0.05).The arterial partial pressure of oxygen at T
2
and T
3
in group A was statistically higher than that in group B,with significant difference (P＜0.05).The oxygenation index at T
3
in group A was statistically higher than that in group B,with significant difference(P＜0.05).
Conclusion
Lung protection ventilation strategy in elderly patients can improve perioperative oxygenation function,reduce the PACU resident time and decrease the incidence of subcutaneous emphysema.
2019 Vol. 26 (3): 67-69转73 [
Abstract
] (
83
)
HTML
(42 KB)
PDF
(0 KB) (
17
)
70
Application effect of epidural combined general anesthesia in laparoscopic rectal cancer resection
SHEN QiLIU Wen-guang
Objective
To investigate the application effect of epidural combined general anesthesia in laparoscopic rectal cancer resection.
Methods
A total of 50 patients with ASAⅠ-Ⅱ who underwent laparoscopic rectal cancer resection in our hospital from June 2016 to May 2017 were enrolled in the study,the patients were randomly assigned to the observation group and the control group,25 cases in each group.The observation group was given an epidural anesthesia under general anesthesia,and the control group was given general anesthesia.The anesthetic quality of the two groups was compared.
Results
The heart rate(HR)and mean arterial pressure(MAP)of T
1
,T
2
,T
3
and T
4
in the observation group were lower than those in the control group(P＜0.05).The quality of recovery of the correct answer time,extubation time,and blink time in the observation group were shorter than those in the control group,and the incidence of irritability during the recovery period of the observation group was lower than that of the control group(P＜0.05).The Ricker sedation-incitement score of the observation group at 12 hours after anesthesia was lower than that of the control group (P＜0.05).The Ricker sedation-incitement score of the observation group at 24 hours and 36 hours after anesthesia were higher than those of the control group(P＜0.05).The pain scores of the observation group in each period were lower than those of the control group (P＜0.05).
Conclusion
Epidural combined general anesthesia is more stable than general anesthesia in laparoscopic rectal cancer resection.The vital signs are more stable and the quality of recovery is better.It is worthy of popularization and application.
2019 Vol. 26 (3): 70-73 [
Abstract
] (
100
)
HTML
(38 KB)
PDF
(0 KB) (
8
)
74
Application effect of preemptive analgesia with Flurbiprofen Axetil and postoperative analgesia with Pentazocine for laparoscopic radical nephrectomy
Objective
To investigate the application effect of preemptive analgesia with Flurbiprofen Axetil and postoperative analgesia with Pentazocine for laparoscopic radical nephrectomy.
Methods
A total of 40 patients with laparoscopic radical nephrectomy from January 2014 to December 2017 were selected and randomly divided into the observation group and the control group,20 patients in each group.Patients in the observation group were given Flurbiprofen Axetil with 50 mg half an hour before the start and the end of the surgery,while patients in the control group were given the same volume of physiological saline.All patients were treated with intravenous controlled analgesia pump 10 minutes before the end of the operation.Patients in the observation group were treated with Sufentanil with 150 μg+Pentazocine with 60 mg+Tropisetron with 5 mg,while patients in the control group were treated with Sufentanil with 200 μg+Tropisetron with 5 mg.The mean arterial pressure(MAP)and heart rate(HR)were observed before anesthetization(T
0
)and at the time of operation starting(T
1
),operation ending(T
2
)and extubation(T
3
)in the two groups.The levels of interleukin-6 (IL-6)and tumor necrosis factor-α (TNF-α)were detected before anesthetization and at the time of 2,12,24 h after operation in the two groups.The VAS scores and BCS scores were recorded at the time of 2,12,24 h after operation in the two groups.The press times of PCIA and the incidence rate of adverse reactions were observed in the two groups.
Results
At T
1
,T
2
and T
3
,the values of MAP and HR in the observation group were significantly lower than those in the control group(P＜0.05).At the 12 h and 24 h after operation,the level of IL-6 and TNF-α in the observation group were significantly lower than those in the control group(P＜0.05).The VAS scores in the observation group were significantly higher than those in the control group(P＜0.05)at the same time point,while the BCS scores in the observation group were significantly lower than those in the control group(P＜0.05)at the same time point.The press times of PCIA in the observation group were significantly lower than those in the control group(P＜0.05),and the incidence of postoperative nausea in the observation group was significantly lower than those in the control group,with significant difference (P＜0.05).
Conclusion
The analgesic effect of preemptive analgesia with Flurbiprofen Axetil and postoperative analgesia with Pentazocine for laparoscopic radical nephrectomy is definite,which can effectively reduce the stress response and adverse reactions.
2019 Vol. 26 (3): 74-77 [
Abstract
] (
99
)
HTML
(43 KB)
PDF
(0 KB) (
17
)
78
Diagnostic value of transvaginal color Doppler ultrasonography for endometrial lesions
WANG Xin-xin
Objective
To investigate the diagnostic value of transvaginal color Doppler ultrasonography for endometrial lesions.
Methods
A total of 106 patients with endometrial lesions who were admitted to our hospital from January 2016 to December 2017 were selected as study subjects.All patients were given transvaginal color Doppler ultrasonography.The results of the examination were compared with the surgical pathology results.
Results
After study,patients with endometrial cancer were found to have uterine effusion;for the patients with endometrial cancer,endometrial complex hyperplasia,the thickness of the endometrium was＞10 mm;there were no significant differences in resistance index(RI)between endometrial complex hyperplasia and endometrial polyps(P＞0.05);the differences of the RI values of the patients with endometrial complex hyperplasia,endometrial polyps and endometrial cancer were statistically significant(P＜0.05);compared with the results of surgical pathological diagnosis,the diagnostic coincidence rates of transvaginal color Doppler ultrasound diagnosis for endometrial complex hyperplasia,endometrial polyps,and endometrial cancer were 93.75%,100.00%,and 95.00%,respectively.
Conclusion
Transvaginal color Doppler ultrasonography is used to diagnose endometrial lesions,and the detection rate is high.It is a non-invasive examination and has almost no damage to the uterus,which is worthy of further investigation and promotion in clinical practice.
2019 Vol. 26 (3): 78-80 [
Abstract
] (
99
)
HTML
(31 KB)
PDF
(0 KB) (
13
)
81
Effect comparison of CT and MRI in the diagnosis of occult fracture of the knee
CONG Xi-da1，2DING Lei3WEI Wen-zhou1GAO Zhen-hua2，3▲
Objective
To compare the effect of computed tomography (CT)and magnetic resonance imaging (MRI)in the diagnosis of occult fracture of the knee.
Methods
From March 2013 to November 2017,68 patients with clinically suspected occult fracture of the knees were enrolled in the Department of Radiology of Huizhou Zhongda Huiya Hospital or the First Affiliated Hospital of Sun Yat-sen University.All patients underwent CT and MRI within 1 week.The results based on surgical diagnosis and clinical follow-up were used as the diagnostic criteria to compare the sensitivity,specificity and accuracy of CT and MRI in the diagnosis of occult fractures of the knee.
Results
There were 61 subjects in total definitely diagnosed as occult fracture of the knee,and the rest 7 ones suffered from clinical pain due to other reasons.There was no statistical difference in the sensitivity of CT and MRI diagnosis(P＞0.05).The specificity of MRI diagnosis was higher than that of CT diagnosis with a significant difference (P＜0.05).The accuracy of MRI diagnosis was also higher compared with that of CT with statistical significance(P＜0.05).
Conclusion
MRI is superior to CT in the diagnosis of patients with the occult fracture of the knee.
2019 Vol. 26 (3): 81-83转86 [
Abstract
] (
99
)
HTML
(34 KB)
PDF
(0 KB) (
11
)
84
Application value of CT in the diagnosis of diffuse thoracic diseases
LIU Bo ZHONG Zeng-you LI Zeng-you
Objective
To analyze the application value of CT in diagnosing diffuse thoracic diseases.
Methods
From January 2015 to June 2017,50 patients with diffuse chest diseases were examined by X-ray and CT.The CT findings of the patients were summarized and the results of the two methods were compared.
Results
50 cases were examined by chest CT,20 cases had obvious scattered patchy shadow,11 cases had nodular shadow,10 cases had ground glass shadow,4 cases had reticular shadow,3 cases had chestnut high density shadow,2 cases had honeycomb shadow.Compared with X-ray,the excellent and good rate of CT scanning image was significantly higher(P＜0.05),and the positive rate of diagnosis was 100%and 82.00%respectively (P＜0.05).
Conclusion
In the diagnosis of thoracic diffuse diseases,chest CT scanning has high definition and ideal image quality,which is convenient for doctors to observe the imaging features of patients carefully and analyze the types of diseases accurately.
2019 Vol. 26 (3): 84-86 [
Abstract
] (
75
)
HTML
(28 KB)
PDF
(0 KB) (
14
)
87
Study of CT differential diagnosis for cystic lung cancer and thin-walled cavitary lung cancer
GAO FengPENG Rong-huaHUANG Yong-suiSHEN Xiao-bin TAN Chuan-yun
Objective
To analyze the CT findings and pathological basis of complete or most cystic lung cancer and cavitary lung cancer.
Methods
A retrospective analysis of chest CT findings in 30 patients with pathologically confirmed lung cancer from January 2017 to January 2018 and 38 patients with complete or most cystic lung cancer was performed.The pathological manifestations of the two types were comparatively analyzed.
Results
On CT images,in 30 thin-walled cavitary lung cancer,CT images showed wall thickness was 2-4 mm,no “air-liquid level sign”,unsmooth inner wall,and surrounding patch cords in 4 cases.The CT findings of 38 patients with cystic lung cancer were mainly cystic changes in the lung,19 cases were in complete cystic changes with smooth and sharp edges and unified inner density in water-like density,and two of them were combined with “air-liquid level”.For the rest 19 cases,most of them were in cystic changes presenting with uneven wall thickness,and some strip-like and nodular thickening.With regard to pathological changes,in the thin-walled cavitary lung cancer,4 cases were squamous cell carcinoma and 26 cases were adenocarcinoma.Under light microscopy,a large number of cancer cells in the necrotic area,or a large number of cancer cells combined with small necrotic areas.Among the cystic lung cancers,29 were adenocarcinomas and 9 were squamous cell carcinomas.Under light microscopy,there were large necrotic areas or a large number of fibrosis and fibrotic tissue degeneration,and a few pathological sections were presented with a large number of cancer cells combined with small necrotic areas.
Conclusion
CT can identify cystic lung cancer from thin-walled cavitary lung cancer,and the thin wall malignant lesions with irregular inner wall should be alert to lung cancer.
2019 Vol. 26 (3): 87-89 [
Abstract
] (
87
)
HTML
(30 KB)
PDF
(0 KB) (
14
)
90
Application value of ultrasound in prenatal diagnosis of thalassemia fetus
CHEN Hou-hong WU Mei-meiLI Da-hui
Objective
To investigate the application significance of ultrasound in prenatal diagnosis of thalassemia fetus.
Methods
From January 2016 to January 2018,150 pregnant women whose fetuses were diagnosed as thalassemia in our hospital and 150 normal singleton pregnant women with normal fetuses were selected as observation group and control group respectively.Ultrasound was performed on these pregnant women,the detection of thalassemia by ultrasound was calculated.The blood flow velocity of middle cerebral artery,resistance index,biparietal diameter,cardiothoracic ratio and placental thickness of the two groups were measured and compared.The correlation between ultrasound test indexes and thalassemia was analyzed using multivariate Logistic regression.
Results
The detection rate of ultrasound for thalassemia was 94.67%.The detection rates of anemia caused by α-thalassemia,β-thalassemia and ABO blood group incompatibility were 96.34%,93.55%and 91.89%,respectively.The blood flow velocity of the middle cerebral artery,biparietal diameter,cardiothoracic ratio and placental thickness in the observation group were higher than those in the control group (P＜0.05),and the resistance index was lower than that in the control group (P＜0.05).After multivariate Logistic regression analysis,the blood flow velocity of the middle cerebral artery,resistance index,biparietal diameter,cardiothoracic ratio,and placental thickness were all closely related to thalassemia.
Conclusion
The use of ultrasound-related data and indicators for prenatal screening and diagnosis of thalassemia can provide a basis for prenatal diagnosis of thalassemia.
2019 Vol. 26 (3): 90-92 [
Abstract
] (
89
)
HTML
(30 KB)
PDF
(0 KB) (
16
)
93
Effect analysis of combined application of CT and MRI techniques in the diagnosis of intrahepatic cholangiocarcinoma
LIU Guo-ai1LIU Bin1SUN Dai-lin2
Objective
To study the combined application effect of CT and MRI in the diagnosis of intrahepatic cholangiocarcinoma (ICC).
Methods
One hundred patients with ICC admitted to the First People′s Hospital of Xiantao City,Hubei Province from December 2017 to August 2018 were selected as subjects.They were randomly divided into control group(50 cases)and observation group(50 cases)according to computer randomization.The control group underwent CT diagnosis,and the observation group underwent CT and MRI combined diagnosis.The sensitivity,specificity,diagnostic coincidence rate and misdiagnosis rate were compared between the two groups.
Results
There was no significant difference in sensitivity between the two groups (P＞0.05).There was significant difference in specificity between the two groups(P＜0.05).The misdiagnosis rate of patients in the observation group was 2.00%,and the rate of missed diagnosis was 2.00%,which was lower than those of the control group,and the differences were statistically significant(P＜0.05).
Conclusion
The combined application effect of CT and MRI in the diagnosis of ICC is very significant,with high sensitivity and specificity,and can prevent misdiagnosis and missed diagnosis.It is worthy of promotion.
2019 Vol. 26 (3): 93-95 [
Abstract
] (
89
)
HTML
(30 KB)
PDF
(0 KB) (
16
)
96
Application of musculoskeletal ultrasound in traumatic superficial soft tissue injury
SHAO WeiGUAN MinXU Guang-yu
Objective
To study the application value of musculoskeletal ultrasound in traumatic superficial soft tissue injury.
Methods
From January 2017 to September 2018,100 patients suspected with traumatic superficial soft tissue injury in our hospital were selected,all patients were examined by X-ray and musculoskeletal ultrasonography.The results of operative diagnosis were the gold standard,the diagnostic results of X-ray and musculoskeletal ultrasonography for traumatic superficial soft tissue injury were compared,and the consistency between the diagnostic results of X-ray and musculoskeletal ultrasonography and the operative diagnosis results was analyzed.
Results
The diagnostic sensitivity,specificity and accuracy of musculoskeletal ultrasound for traumatic superficial soft tissue injury were higher than those of X-ray(P＜0.05).The diagnostic coincidence rate of musculoskeletal ultrasound for muscle injury,tendon injury,ligament injury and meniscus injury was higher than that of X-ray (P＜0.05).The consistency analysis showed that the diagnostic results of musculoskeletal ultrasonography were in good agreement with those of surgical diagnosis,and the consistency between X-ray and surgical diagnosis was moderate.
Conclusion
The musculoskeletal ultrasound has a good diagnostic value for the diagnosis of traumatic superficial soft tissue injury.It can detect sensitive superficial soft tissue injury and distinguish the type of soft tissue injury.
2019 Vol. 26 (3): 96-98 [
Abstract
] (
73
)
HTML
(32 KB)
PDF
(0 KB) (
17
)
99
Clinical effect of Yiguan Decoction Add or Reduce Medicine combined with Methotrexate and Hydroxychloroquine in the treatment of Sjogren syndrome
HUANG Xun-fang LI Xue-yong LIU Ju▲
Objective
To investigate the clinical effect of Yiguan Decoction Add or Reduce Medicine combined with Methotrexate and Hydroxychloroquine in the treatment of Sjogren syndrome.
Methods
From January 2016 to December 2017,60 patients with Sjogren syndrome admitted to the First People′s Hospital of Jiujiang City in Jiangxi Province were selected as subjects.Patients were divided into control group(30 cases)and treatment group(30 cases)according to random number table method.The control group was treated with Methotrexate combined with Hydroxychloroquine.The treatment group was treated with Yiguan Decoction Add or Reduce Medicine combined with Methotrexate and Hydroxychloroquine.The total effective rate was compared between the two groups after 8 weeks of treatment.The results of eye Schimer test,dry mouth symptom score,dry eyes symptom score,serum C-reactive protein (CRP)level and erythrocyte sedimentation rate (ESR)at 4 and 8 weeks of treatment were compared between the two groups.
Results
The total effective rate of treatment in the treatment group was higher than that in the control group,and the difference was statistically significant (P＜0.05).The results of the Schimer test at 8 weeks of treatment were significantly higher than that at 4 weeks of treatment,the differences were statistically significant(P＜0.05).The results of the Schimer test in the treatment group at 4 and 8 weeks of treatment were significantly higher than those in the control group,the differences were statistically significant(P＜0.05).The scores of dry eyes and dry mouth at 8 weeks of treatment were significantly lower than those at 4 weeks of treatment,the differences were statistically significant(P＜0.05).The scores of dry eyes and dry mouth in the treatment group at 4 and 8 weeks of treatment were significantly lower than those in the control group,the differences were statistically significant(P＜0.05).The CRP and ESR levels at 8 weeks of treatment in both groups were significantly lower than that at 4 weeks of treatment,the differences were statistically significant(P＜0.05).The CRP and ESR levels in the treatment group at 4 and 8 weeks of treatment were significantly lower than those in the control group,with statistically significant differences (P＜0.05).
Conclusion
Yiguan Decoction Add or Reduce Medicine combined with Methotrexate and Hydroxychloroquine in the treatment of Sjogren syndrome,the clinical efficacy is better than Methotrexate combined with Hydroxychloroquine treatment.
2019 Vol. 26 (3): 99-102 [
Abstract
] (
87
)
HTML
(35 KB)
PDF
(0 KB) (
14
)
103
Clinical effect of Alprostadil in the treatment of chronic renal failure
WU Wen-shengZHONG Yu-tingYU Xian-li
Objective
To study the clinical effect of Alprostadil in the treatment of chronic renal failure(CRF).
Methods
Sixty-six patients with CRF admitted from December 2016 to December 2017 were enrolled as study subjects.The participants were divided into control group (n=33)and experimental group (n=33)according to the odd or even number.In the control group,conventional drug was used,while in the experimental group,Alprostadil was adopted.The therapeutic effect,renal function indicators before and after treatment,24 h urine protein,blood rheology indicators before and after treatment were compared in the two groups.
Results
After 14-day drug treatment,the total therapeutic effectiveness rate of the experimental group was 81.82%,which was higher than that of control group (63.64%)with a significant difference(P＜0.05).The renal function indicators such as blood urea nitrogen(BUN),serum creatinine(SCr)and 24 h urine protein after treatment in the experimental group were all lower compared with those before treatment,creatinine clearance rate(Ccr)was higher compared with before treament with significant differences(P＜0.05).The renal function indicators such as BUN,SCr and 24 h urine protein after treatment in the experimental group were lower compared with those of the control group,Ccr was higher than that in the control group with statistical significance(P＜0.05).The blood rheology indicators such as the whole blood low-shear viscosity,whole blood high-shear viscosity,blood cell aggregation index,blood viscosity,haematocrit,erythrocyte deformation index after treatment in the experimental group were lower compared with those before treatment(P＜0.05).The above-mentioned blood rheology indicators in the experimental group after treatment were lower compared with those in the control group with statistical significance (P＜0.05).
Conclusion
The treatment of Alprostadil in patients with CRF can improve patient′s renal function and hemorheology indicators,which is worthy of promotion and application.
2019 Vol. 26 (3): 103-105转109 [
Abstract
] (
84
)
HTML
(34 KB)
PDF
(0 KB) (
17
)
106
Effect of Glucocorticoid combined with Cyclophosphamide on myasthenia gravis
CHEN Xun
Objective
To evaluate the efficacy of Glucocorticoid combined with Cyclophosphamide in the treatment of myasthenia gravis.
Methods
A total of 120 patients with myasthenia gravis treated in our hospital from February 2016 to February 2018 were selected as subjects.According to the computer randomization method,the patients were divided into control group and experimental group,60 cases in each group.The control group was treated with Glucocorticoids.The experimental group was treated with Glucocorticoid combined with Cyclophosphamide.The respiratory function,serum indicators,clinical symptom score,clinical treatment effect and adverse reactions of the two groups were analyzed.
Results
The total effective rate of the experimental group was higher than that of the control group,the difference was statistically significant(P＜0.05).The clinical symptom scores of the experimental group were lower than those of the control group,the differences were statistically significant(P＜0.05).The respiratory muscle endurance,vital capacity and maximum ventilation of the experimental group were higher than those in the control group,but the myasthenic level was lower than that in the control group,the differences were statistically significant(P＜0.05).The interleukin-18(IL-18)level in the experimental group was lower than that in the control group,and the transforming growth factor-β1 (TGF-β1)level was higher than that in the control group,the differences were statistically significant(P＜0.05).The difference in total incidence of adverse reactions was not statistically significant between the two groups(P＞0.05).
Conclusion
Glucocorticoid combined with Cyclophosphamide in the treatment of myasthenia gravis can not only improve the patient′s respiratory function and serum indicators,but also relieve the clinical symptoms and signs with high safety,thus is worthy to be promoted.
2019 Vol. 26 (3): 106-109 [
Abstract
] (
75
)
HTML
(36 KB)
PDF
(0 KB) (
10
)
110
Clinical effect of Entecavir in the treatment of chronic hepatitis B combined with hepatic steatosis
LI Ran
Objective
To investigate the clinical effect of Entecavir in the treatment of chronic hepatitis B with hepatic steatosis.
Methods
Eighty patients with chronic hepatitis B and hepatic steatosis admitted to our hospital from February to November in 2017 were aelected as subjects.The patients were equally divided into observation group and control group according to computer randomization.In the observation group,Entecavir was used,and in the control group,Rosuvastatin was adopted.The serum alanine aminotransferase (ALT),hepatitis B virus-DNA,blood lipid index and therapeutic effect were compared between the two groups.
Results
After treatment,the serum ALT and hepatitis B virus-DNA of patients in the observation group were lower than those in the control group,the differences were statistically significant(P＜0.05).After treatment,the total cholesterol,triglyceride and low density lipoprotein cholesterol in the observation group were lower than those in the control group,and the high density lipoprotein cholesterol was higher than that in the control group,the differences were statistically significant(P＜0.05).The total effectiveness rate of the observation group was higher than that of the control group with a statistical difference (P＜0.05).
Conclusion
The efficacy of Entecavir in the treatment of chronic hepatitis B with hepatic steatosis is very significant,which can improve the blood lipid index,and is worthy of study.
2019 Vol. 26 (3): 110-112 [
Abstract
] (
72
)
HTML
(31 KB)
PDF
(0 KB) (
15
)
113
Analysis on the application of antibiotics in inpatients in our hospital in 2017
CAI Jing LI Ya-tan JIA Man-qing LIU Jun▲
Objective
To investigate the use of antibacterials to the inpatients in the Second Hospital Attached to Xinjiang Medical University(hereinafter referred to as “our hospital”)so as to offer references for rational use of antibacterials.
Methods
A retrospective analysis was done on the application data antibacterial drugs including the total cost,the antibacterial use density(AUD),the defined daily dose system (DDDs),graded use,the submission of specimen and the distribution of detected bacteria in our hospital from January to December 2017.
Results
In terms of total cost and DDDs,Cephalosporin,Penicillin,Cephamycins,Macrolides,Quinolones,Carbopenems ranked the first ten frequently used antibacterials.The highest frequency of antibiotic use occurred in the department of paediatrics.In comparison,antibacterials of restricted use took up the largest proportion while antibacterials of special use accounted the smallest.The submission rate of clinicalpathogenic microorganism specimen of inpatients before the therapeutic use of antibacterials has reached the standard.
Conclusion
The application of antibacterial drugs is reason-able basically,but management still should be strengthened and reasonable selection of perioperative preventivemedicine.To achieve the purpose of safe,effective and economical medication.
2019 Vol. 26 (3): 113-116 [
Abstract
] (
85
)
HTML
(41 KB)
PDF
(0 KB) (
12
)
117
Clinical effects of application of Rehabilitation New Liquid combined with Omeprazole in treatment of non-Helicobacter pylori infection peptic ulcer
SHI Yan-qing1LIU Bin2ZHANG Meng-meng1ZHOU Ting2XU Fang2ZHANG Juan3▲
Objective
To explore the clinical efficacy of Rehabilitation New Liquid combined with Omeprazole in the treatment of non-Helicobacter pylori infection peptic ulcer.
Methods
Altogether 84 patients with peptic ulcer who met the requirements in Affiliated Hospital of Jiujiang University from January 2017 to April 2018 were selected as subjects and randomly divided into case group and control group,with 42 cases in each group.The control group was treated with Omeprazole,while the case group was treated with Rehabilitation New Liquid combined with Omeprazole.The clinical effects of the two groups were observed and compared.The levels of inflammatory cytokines were measured before and after treatment in both groups.The adverse reactions of the two groups were compared.The recurrence of gastric ulcer was compared between the two groups during follow-up.
Results
The total effective rate of the patients in the case group was 95.24%,which was higher than that in the control group (78.57%),and the difference was statistically significant(P＜0.05).The levels of interleukin-6(IL-6),tumor necrosis factor α (TNF-α)and C-reactive protein(CRP)in the two groups before treatment were not statistically significant(P＞0.05),while the levels of IL-6,TNF-α and CRP after treatment were lower than before treatment,and the differences were statistically significant(P＜0.05).The levels of IL-6,TNF-α and CRP in the case group after treatment were lower than those in the control group,and the differences were statistically significant(P＜0.05).There was no statistically significant difference in the overall incidence of adverse reactions between the two groups(P＞0.05).Gastroscopy review after 2 months of follow-up showed that the recurrence rate of patients in the case group(4.76%)was lower than that in the control group(19.05%),and the difference was statistically significant(P＜0.05).
Conclusion
Rehabilitation New Liquid combined with Omeprazole is effective in the treatment of peptic ulcer,which has synergistic effect and is worthy of clinical promotion.
2019 Vol. 26 (3): 117-119 [
Abstract
] (
110
)
HTML
(35 KB)
PDF
(0 KB) (
12
)
120
Clinical effect of Lyophilized Recombinant Human Brain Natriuretic Peptide combined with Levosimendan in the treatment of acute heart failure
YANG Li-hui
Objective
To study the clinical effect of Lyophilized Recombinant Human Brain Natriuretic Peptide combined with Levosimendan in patients with acute heart failure.
Methods
Ninety-two patients with acute heart failure admitted to the First People's Hospital of Hechi City from April 2017 to April 2018 were selected as the data subjects.According to the random number table method,they were divided into study group(n=46)and control group(n=46).Patients in the control group were treated with Levosimendan alone,while those in the study group were treated with Lyophilized Recombinant Human Brain Natriuretic Peptide combined with Levosimendan.The clinical treatment efficiency of the two groups was compared.The changes of B-type natriuretic peptide level,serum uric acid level and cardiac function indexes (left ventricular ejection fraction [LVEF]and left ventricular end-diastolic diameter[LVEDD])before and after treatment in the two groups were compared.
Results
The total effective rate in the study group was higher than that in the control group,and the difference was statistically significant(P＜0.05).Before treatment,there were no statistically significant differences in B-type natriuretic peptide level,serum uric acid level,LVEF and LVEDD between the two groups(P＞0.05).After treatment,the level of B-type natriuretic peptide and serum uric acid in the study group were significantly lower than those in the control group,and LVEF and LVEDD were significantly higher than those in the control group,with statistically significant differences(P＜0.05).After treatment,the level of B-type natriuretic peptide and serum uric acid in the two groups were significantly lower than those before treatment,and LVEF and LVEDD were significantly higher than those before treatment,with statistically significant differences (P＜0.05).
Conclusion
The application of Lyophilized Recombinant Human Brain Natriuretic Peptide combined with Levosimendan in the treatment of acute heart failure is beneficial to the improvement of clinical treatment.
2019 Vol. 26 (3): 120-122 [
Abstract
] (
85
)
HTML
(32 KB)
PDF
(0 KB) (
10
)
123
Clinical effect of moxibustion combined with acupoint sticking in the treatment of senile depression
PENG Jian1OUYANG Wei2LI Mei1▲ ZENG Shen-juan2
Objective
To observe the clinical effect of moxibustion combined with acupoint application in the treatment of senile depression patients.
Methods
From September 2017 to April 2018,64 patients with senile depression who were admitted into the psychiatric department of our hospital and cooperative hospital were randomly assigned(according to the random number table method)to the treatment group and the control group,with 32 patients in each group.The control group was given Sertraline Hydrochloride for treatment,while the treatment group was given moxibustion and acupoint application on the basis of oral Sertraline Hydrochloride Tablets.The score of Hamilton depression scale(HAMD)before and after treatment and the curative effect in the two groups were observed.
Results
The HAMD scores of the two groups were lower than those of the control group after 2,4 and 8 weeks treatment,and the differences were statistically significant(P＜0.05).The HAMD scores of the treatment group after 2,4 and 8 weeks of treatment were lower than those of the control group,and the differences were statistically significant(P＜0.05).After 8 weeks of treatment,the total effective rate was 93.75%in the treatment group,which was higher than that of the control group(84.38%),and the difference was statistically significant(P＜0.05).
Conclusion
Moxibustion combined with acupoint application has a significant effect treating senile depression.
2019 Vol. 26 (3): 123-125 [
Abstract
] (
101
)
HTML
(34 KB)
PDF
(0 KB) (
13
)
126
Effect of simultaneous treatment of heart and gallbladder meridian for acupuncture treating shaoyang headache
LI Kong-zheng1LI Sheng-ju2LI Yu-hong3
[
Abstract
]
Objective
To explore the clinical effect of simultaneous treatment of heart and gallbladder meridian for acupuncture treating shaoyang headache.
Methods
All of 116 patients with shaoyang headache treated by Rehabilitation Physiotherapy Center in Yangjiang People′s Hospital from May 2016 to January 2018 were selected.They were divided into the two groups with 58 cases in each group according to the principle of random drawing lots.The control group was treated with local acupoints for acupuncture while the observation group was treated with simultaneous treatment of heart and gallbladder meridian for acupuncture.After 3 weeks of treatment,the clinical effect between the two groups was compared.
Results
After 3 weeks of treatment,the VAS scores of the two groups were significantly decreased(P＜0.05),and the VAS score of the observation group was significantly lower than that of the control group(P＜0.05).The total effective rate of the observation group was 87.9%,which was significantly higher than that of the control group (75.9%),and the difference was statistically significant(χ
2
=5.887,P=0.0021).
Conclusion
Simultaneous treatment of heart and gallbladder meridian for acupuncture treating shaoyang headache can better improve the headache symptoms of patients,the effect is affirmative,and it is worth promoting.
2019 Vol. 26 (3): 126-128 [
Abstract
] (
76
)
HTML
(35 KB)
PDF
(0 KB) (
14
)
129
Exploration of application of Yun-Qi theory in clinical practice
QIU Feng-xi1SHI Jie-yu2GU LI-hua2ZHANG Hong1▲
The theory of five movements and six qi is an important part of the theoretical system of traditional Chinese medicine,it is widely used in dialectical treatment,prescription,disease prevention and treatment,health care,epidemiological analysis and so on.The core idea of the theory of Yun-Qi is"correspondence between man and universe",and the phenology,the movement of the sun,moon and stars and the human body it containing are in dynamic change,and in this process,the"lung system"plays an important role in linking the internal and external of the human body,communicating natural air and human air,and making human changes consistent with external changes.Therefore,it can also be said that"lung system"is the"medium"of correspondence between man and universe.In addition,this paper draws the corresponding pattern map of correspondence between man and universe in order to provide theoretical basis for clinical treatment based on the theory of five movements and six qi.
2019 Vol. 26 (3): 129-132 [
Abstract
] (
64
)
HTML
(41 KB)
PDF
(0 KB) (
13
)
133
Experience summary of professor ZHANG Yu-qin treating diabetic peripheral neuropathy
CHEN Xi-huiZHANG Yu-qin▲
This paper introduces mainly the clinical experience of professor ZHANG Yu-qin as a famous veteran expert of traditional Chinese medicine treating diabetic peripheral neuropathy (DPN).Professor ZHANG Yu-qin thinks that qi deficiency and blood stasis is the basic pathogenesis of DPN,which is characterized by deficiency in origin and excess in superficiality taking qi deficiency as the origin and qi deficiency is reflected in the difference between lung,stomach(spleen)and kidney qi deficiency,while blood stasis is the superficiality.Although blood stasis is a pathological product,it has become a pathogenic factor when it develops into the disease.In the treatment,professor ZHANG Yu-qin puts forward the treatment principle of invigorating qi and activating blood circulation,removing blood stasis and dredging collaterals.In clinical practice,self-made Tangbikang for plusing and subtraction for oral administration,combined with Tangtong external wash and Tangbi external wash conducting the herbal fumigation,and it improves the main clinical symptoms of pain numbness in DPN patients,and improvs the clinical efficacy.
2019 Vol. 26 (3): 133-135 [
Abstract
] (
80
)
HTML
(32 KB)
PDF
(0 KB) (
15
)
136
Effect of “lifting and shaking hand manipulation”method combined with paired needling in the treatment of diarrhea-type irritable bowel syndrome
YANG Wu-bin SHAN Xing-yu HE Yuan
Objective
To analyze the effect of “lifting and shaking hand manipulation” method combined with paired needling in the treatment of diarrhea-type irritable bowel syndrome (IBS).
Methods
From January 2017 to February 2018,65 eligible patients with diarrhea-type IBS treated in Guangzhou Zengcheng Traditional Chinese Medicine Hospital were selected as study subjects.According to the drawing lots,they were divided into the control group(32 cases)and the treatment group(33 cases).They were treated with western medicine and“lifting and shaking hand manipulation”method combined with paired needling.The total effective rate and IBS-symptom severity score(IBS-SSS)before and after treatment were compared between the two groups.
Results
The total effective rate of the treatment group was 96.97%,which was significantly higher than that of the control group(75.00%),and the difference was statistically significant(P＜0.05).There was no significant difference of IBS-SSS score between the two groups before treatment(P＞0.05).The IBS-SSS score in the treatment group was lower than that in the control group after treatment,and the difference was statistically significant(P＜0.05).
Conclusion
The “lifting and shaking hand manipulation” method combined with paired needling treating diarrhea-type IBS obtains a clear effect,which can effectively improve the severity of the patients′condition and is worthy of clinical promotion.
2019 Vol. 26 (3): 136-138 [
Abstract
] (
61
)
HTML
(31 KB)
PDF
(0 KB) (
17
)
139
Influence of traditional Chinese medicine dietary therapy on blood phosphorus level and quality of life in patients with hemodialysis
ZHENG Jian-qin
Objective
To study the influence of traditional Chinese medicine (TCM)diet therapy on blood phosphorus level and quality of life(QOL)in patients with hemodialysis.
Methods
A total of 100 patients with hemodialysis treated in our hospital from May 2017 to May 2018 were selected as the study subjects.All patients were divided into the two groups using the random number table methosd,with 50 cases in each group.In the control group,routine dietary care was used,while in the experimental group,TCM diet therapy was adopted.The blood phosphorus level,and score of QOL including physiological function,psychological function,social function and health status between the two groups were compared.
Results
The blood phosphorus level of the experimental group was lower than that of the control group,and the scores of physiological function,psychological function,social function and health status of QOL in the experimental group were higher than those of the control group,and the differences were statistically significant(P＜0.05).
Conclusion
The implementation of TCM diet therapy for patients with hemodialysis can effectively improve the blood phosphorus level of patients and improve their QOL.It has a high clinical application value and is worthy of clinical promotion and application.
2019 Vol. 26 (3): 139-141 [
Abstract
] (
78
)
HTML
(30 KB)
PDF
(0 KB) (
10
)
142
Analysis of drug resistance and drug resistance gene of group B streptococcus in perinatal women of Huizhou City
LIN Bao-an
Objective
To analyze the drug resistance and drug resistance gene of group B streptococcus in perinatal women.
Methods
A total of 657 perinatal women admitted into the Department of Obstetrics and Gynecology,Huizhou First Maternal and Child Health Hospital from January 2016 to September 2017 were selected and their genital secretions were taken for culture and detection of group B streptococcus.Group B streptococcus cultured was given drug susceptibility,and its drug resistance was observed and resistance gene were analyzed.
Results
Among 657 perinatal women,213 cases of group B streptococcus were detected,the bacterial bearing rate was 32.4%.Among them,the perinatal women with≥30 years old group had a prevalence rate of 42.3%,and the prevalence rate was 29.8%for perinatal women with ＜30 years old group,and the difference between the two groups was statistically significant(P＜0.05).The resistance rate of group B streptococcus to Penicillin was 0.8%,Erythromycin was 31.2%,Ceftriaxone was 6.3%,and Levofloxacin was 22.5%.Clindamycin was 25.9%,Tetracycline was 63.2%,Vancomycin was 0.0%,Linezolid was 0.3%,Nitrofuranto was 11.3%,Ampicillin was 2.6%,and D-suppressing zone test was 25.0%.The erythromycin resistance gene is mainly ermB,and two or more ermB gene-positive group B streptococci accounting for 13.5%.The Tetracycline resistance genes were mainly teTM and tetO,tetK and tetL.
Conclusion
Infected group B streptococcus in perinatal women is higher resistant to Tetracycline and Erythromycin.It should be avoided in clinical treatment.For Penicillin,Vancomycin,Linezolid,Ampicillin,Nitrofurantoin and Ceftriaxone is highly sensitive,and can be treated according to the specific condition of the patients.
2019 Vol. 26 (3): 142-145 [
Abstract
] (
81
)
HTML
(36 KB)
PDF
(0 KB) (
15
)
146
Analysis of Mycoplasma culture and drug sensitivity results in genitourinary tract
LIU Li-juan WANG Hou-fang SUN Fei
Objective
To know the infection status and drug sensitivity analysis of Ureaplasma urealyticum (Uu)and Mycoplasma hominis(Mh)of genitourinary tract in patients with urogenital tract infection,and recommend empiric drugs to clinic for the treatment of Mycoplasma infection in genitourinary tract.
Methods
A total of 1639 samples in patients with urogenital tract infection from January 2011 to December 2017 were collected.All samples were tested using the Biomerieux Mycoplasma IST 2 culture identification and sensitivity test kit.
Results
The positive rate of Mycoplasma in genitourinary tract of all patients was 39.5%(648/1639),of whom 608 cases(37.0%)were Uu infection,11 cases(0.7%)were Mh infection alone,and 29 cases(1.8%)were mixed infection of Uu and Mh(Uu＋Mh).The results of drug sensitivity showed that Uu had the highest sensitivity to Pristinamycine (99.2%),followed by Doxycycline (98.8%)and Ciprofloxacine (the drug resistance rate was 77.8%)had the strongest resistance.The sensitivity rate of Mh to Doxycycline,Pristinamycine and Josamycine was the highest(100.0%)and Erythromycine was the most resistant(the drug resistance rate was 90.9%).The sensitivity rate of Uu+Mh to Doxycycline and Tetracycline was the highest(100.0%),while Erythromycine and Ciprofloxacine were the most resistant(the drug resistance rate was 82.8%).
Conclusion
Ureaplasma urealyticum is the main cause of urogential mycoplasma infection.Doxycycline should be used as the preferred antibiotic for genital mycoplasma infection.
2019 Vol. 26 (3): 146-149 [
Abstract
] (
75
)
HTML
(35 KB)
PDF
(0 KB) (
12
)
150
Application value of serum cystatin C in diagnosis of glomerular damage in patients with early diabetic mellitus
LI Jian-xiong LIANG Huan-lin SU Hui-cong
Objective
To explore the application value of cystatin C (CysC)in in diagnosis of glomerular damage in patients with early diabetic mellitus (DM).
Methods
All of 196 patients with DM treated in our hospital from March 2016 to March 2018 were retrospectively analyzed,and the patients with diabetic nephropathy(DN)were set as the observation group (102 cases)while patients with simple DM were set as the control group (94 cases).CysC,BUN and SCr level inpatients between the two groups were compared,and ROC curve was used to evaluate the diagnostic value of the above-mentioned indexes for DN.
Results
The level of CysC,BUN and SCr in the observation group were significantly higher than those in the control group,and the differences were statistically significant(P＜0.05).ROC curve analysis showed that the diagnostic efficacy of serum CysC for DN was significantly higher than that of BUN and SCr(P＜0.05),the AUC was 0.885,0.715,0.748 respectively.The Youden index indicated that the best cut-off points of CysC,BUN and SCr expression level for diagnosis of DN was≥0.797 mg/L,≥7.273 mmol/L and ≥127.741 μmol/L respectively.The accuracy,sensitivity,specificity,positive predictive value and negative predictive value of CysC were significantly higher than those of BUN and sCR,and the differences were statistically significant(P＜0.05).
Conclusion
CysC has higher sensitivity and specificity in the diagnosis of glomerular damage in patients with early DM.It is worthy of clinical promotion.
2019 Vol. 26 (3): 150-152 [
Abstract
] (
95
)
HTML
(30 KB)
PDF
(0 KB) (
15
)
153
Diagnostic value of HCG and progesterone test for early threatened abortion
XIAO Shi-bin
]
Objective
To evaluate the clinical value of human chorionic gonadotropin (HCG)and progesterone in the diagnosis of early threatened abortion.
Methods
A total of 120 cases of suspected early threatened abortion treated in the outpatient department of our hospital from February 2017 to February 2018 were selected as the study object and set as the observation group.While 120 healthy pregnant women admitted to our hospital during the same period were selected as the control group.Dynamic monitoring of serum HCG and progesterone levels were performed in both groups to compare the differences between the two groups.
Results
The levels of serum HCG and progesterone in the observation group were significantly lower than those in the control group,and the differences were statistically significant(P＜0.05).The specificity,sensitivity and accuracy of HCG combined with progesterone in the diagnosis of early threatened abortion were significantly higher than those of progesterone and HCG alone(P＜0.05).
Conclusion
Dynamic combined monitoring of serum HCG and progesterone levels in pregnant women is helpful to predict early threatened abortion and prognosis of patients,which is worthy of clinical application.
2019 Vol. 26 (3): 153-158 [
Abstract
] (
75
)
HTML
(30 KB)
PDF
(0 KB) (
12
)
159
Clinical value of serum carbohydrate antigen 125,human epididymal secretion protein 4 and ovarian cancer risk prediction index in the early diagnosis of ovarian cancer
XU Mei-mei1CHEN Ting-jian2FANG Li-shan3
Objective
To explore the clinical value of serum carbohydrate antigen 125(CA125),human epididymal secretion protein 4 (HE4)and ovarian cancer risk prediction index (ROMA)in the early diagnosis of ovarian cancer.
Methods
A total of 50 cases of ovarian cancer,50 cases of benign ovarian lesions and 50 cases of healthy physical examination were selected as study objects from February 2017 to July 2018 in our hospital.Serum HE4 and CA125 in the 3 groups were tested by electrochemical luminescence method and their ROMA were calculated for dynamic comparison.The clinical value of single and combined detection in early diagnosis of ovarian cancer was evaluated.Results HE4 and CA125 and ROMA in ovarian cancer group were significantly higher than those in benign ovarian tumor group and healthy control group,and the differences were statistically significant(P＜0.05).The differences of HE4,CA125 and ROMA between the benign ovarian tumor group and the healthy control group were not statistically significant(P＞0.05).Combined detection of HE4,CA125 and ROMA indec had a significant advantage in diagnosing ovarian cancer.
Conclusion
Combined detection of HE4 and CA125 and ROMA index has important clinical value in early diagnosis of ovary.
2019 Vol. 26 (3): 159-161 [
Abstract
] (
69
)
HTML
(32 KB)
PDF
(0 KB) (
15
)
162
Application effect of teamwork in the management of the medication safety
LI Shu-ying1ZHANG Jin-yan2ZHANG Jia-geng3LI Xiu-ying1LIU Jun-ying1WANG Chun-hua1▲
Objective
To explore the application effect of teamwork in the management of the medication safety.
Methods
The medication error events in our hospital from January 2014 to September 2017 were selected as subjects.Before the rectification from January 2014 to September 2015,the management was carried out according to the conventional management methods and working modes,and after the rectification from January 2016 to September 2017,the management was carried out by the multi-department team cooperation models with the management tools.The rate of medication error events,the rate of active reporting of adverse events,and the qualified rate of stored drugs before and after rectification were compared before and after the rectification.
Results
The rate of medication error events after the rectification was significantly lower than that before the rectification,and the difference was statistically significant(P＜0.05).The rate of active reporting of adverse events and the qualified rate of stored drugs after the rectification were significantly higher than those before the rectification,and the differences were statistically significant(P＜0.05).
Conclusion
The application of teamwork mode can establish an effective inter-department communication and coordination mechanism,form a safety management mode,which improves and prevents the drug management from the system,and improve the safety of clinical medication.
2019 Vol. 26 (3): 162-165 [
Abstract
] (
89
)
HTML
(37 KB)
PDF
(0 KB) (
14
)
166
Application effect of incentive mechanism in hospital nursing management
ZENG Xue-qin HUANG Xiao-mei▲ SHI Ke-qin WEN Sheng-ying
]
Nursing management directly influences the quality of care in hospitals,the total service level and image of medical institutions.In order to better ensure the safety of patients and maintain the good operation of the hospitals,it is of great significance to explore the application of incentive mechanism in nursing management for the development of hospitals.Planning and implementing the incentive mechanism in the allocation of nursing resources can comprehensively improve the quality of clinical medical services and personnel training,and it is an important part of hospital construction and development.
2019 Vol. 26 (3): 166-168 [
Abstract
] (
69
)
HTML
(28 KB)
PDF
(0 KB) (
12
)
169
Discussion of the combined teaching of Basic Chemistry and Physical Chemistry course
WEI Yong-biaoWANG Ya-xuan YE YongDONG Min FENG Jie
Basic Chemistry and Physical Chemistry are the basic courses of pharmacy.At present,the two courses are listed and taught by most pharmacy colleges,separately.In order to allow students more time to study professional courses,it is necessary to reduce the class time of the basic course.To learn more basic chemistry knowledge of Basic Chemistry and Physical Chemistry at a limited time,this article discusses the necessity of integrating teaching of Basic Chemistry and Physical Chemistry,the optimized scheme of the course system and the improvement of teaching methods after the combination of the two courses.
2019 Vol. 26 (3): 169-171 [
Abstract
] (
79
)
HTML
(30 KB)
PDF
(0 KB) (
16
)
172
Construction and practice of college-enterprise cooperative training mode for eye optical technology major
WANG Rui
With the increasing demand for optometry talents in the optometry industry,how to cultivate professional and technical talents for industrial and regional economic development has become an urgent problem for optometry vocational education.College-enterprise cooperation is an effective way to solve this problem.Based on the goal of cultivating the professional talents of optometry,this study has established a college-enterprise cooperation training model.Through the construction of the curriculum system,the construction of the teaching staff,the cultivation of professional skills,and the ability of social services,the college-enterprise cooperation training mode will be implemented.It has improved the competitiveness of students′employment,won a good reputation for the school,and reserved a large number of talents for the company,contributing to the development of the regional economy.
2019 Vol. 26 (3): 172-174 [
Abstract
] (
81
)
HTML
(32 KB)
PDF
(0 KB) (
3
)
175
Application study of GMP practice in course of pharmacy administration lessons
JIANG Yun-fang ZHANG Ke-ren LI Xiang-ling HE Xun WU Hong-yan CUI Xing▲
The course of Pharmacy Administration was a required course of pharmacy and related specialties in medical colleges and university.Good Manufacturing Practice (GMP)was an important chapter in the course of Pharmacy Administration and a mandatory standard suitable for pharmaceutical and food industry.In order to enrich the content of Pharmacy Administration,stimulate the interest in learning,and to promote the understanding of GMP,GMP practice teaching has been applied in the course ofpharmacy administration.Students participate in the work of weighing,washing and drying,dispensing,sealing,sterilization and lamp inspection in the form of cosplay,to learn GMP operation process of small-volume injection,promote the study of theoretical knowledge,enhance the ability of practical operation,and lay a foundation for drug production after graduating.
2019 Vol. 26 (3): 175-177 [
Abstract
] (
68
)
HTML
(33 KB)
PDF
(0 KB) (
4
)
178
Meta analysis of the application effect of CP teaching in medical clinical teaching
CHEN Jing1HOU Yong2TAO Yong3
Objective
To evaluate the application effect of CP teaching in medical clinical teaching.
Methods
A total of 38 randomized controlled trials(RCTs)were collected from the full-text database of Chinese journals in the past five years(2012-2017).Literatures were independently selected and data were extracted according to inclusion and exclusion criteria.Data were analyzed by using RevMan 5.3 software.
Results
A total of 29 RCTs were included and more than 1000 students were enrolled.The results showed that CP teaching had significant effects on students′theoretical test scores(SMD=1.82,95%CI[1.70-1.94],P＜0.01),practical skill operation scores(SMD=1.57,95%CI[1.45-1.69],P＜0.01)and case analysis ability test scores(SMD=1.51,95%CI[1.30-1.73],P＜0.01),which were better than general clinical teaching.
Conclusion
CP teaching is a relatively scientific teaching method and can be applied to clinical teaching.
2019 Vol. 26 (3): 178-180转184 [
Abstract
] (
70
)
HTML
(37 KB)
PDF
(0 KB) (
15
)
181
Application effect of situational teaching mode in nursing teaching in our hospital
LI Min-hua PENG Xiang-fu CHEN Ge-ting
Objective
To analyze the application effect of situational teaching mode in nursing teaching in our hospital.
Methods
A total of 56 nursing staff in our hospital were selected as subjects.By randomized grouping,they were divided into control group(n=28)and observation group(n=28).In the control group,traditional teaching method was used from December 2017 to May 2018,while in the observation group,the situational teaching method was adopted during the same period.The differences in teaching effects between the two groups were compared.
Results
On the evaluation of teacher′s teaching quality,in the observation group,the scores of items such as clear explanation of concept and key points highlighting,high preference for such teaching mode,the language was vivid,concise and organized,reflecting the new progress of clinical nursing model,the combination of theory and practice was batter,combining with practical clinical problems,the degree of explaining difficult problems was better,the lively teaching mode arouses students'initiative,the blackboard writing was neat and the explanation sequence was reasonable,the teaching progress was well controlled and the time allocation was reasonable,and teachers play a guiding role rather than indoctrinating knowledge,with statistical difference,etc.were significantly higher than those of the control group(P＜0.05).On regard to student behavior evaluation,the professional nursing behavior level,flexible learning,clinical analysis ability,questioning ability,knowledge expansion,creative thinking and immediate response,cooperation,and thinking ability from patients′perspective were significantly higher in the observation group than those in the control group,with statistical difference(P＜0.05).
Conclusion
Compared with the traditional teaching mode,application of scenario simulation teaching mode in nursing teaching can effectively improve teachers′teaching quality and students′behavioral ability,and promote nursing staff to change from passive acceptance to active learning,thereby enhancing the overall quality of care in the hospital and reducing the incidence of nurse-patient disputes,which has a clinical application value.
2019 Vol. 26 (3): 181-184 [
Abstract
] (
75
)
HTML
(33 KB)
PDF
(0 KB) (
15
)
185
Research on the change of medical informatics education in the big data environment
ZHAO Yu-hui
Medical informatics is an interdisciplinary science,which includes hospital information,clinical information,nursing information,medical education information,biomedical information and so on.From the point view of discipline,medical informatics mainly studies the application of information technology and information science in the field of medicine.It is an important subject oriented to medical application.With the rapid development of information technology,medical informatics education has been faced with unprecedented opportunities and challenges.Therefore,this paper mainly describes the background of large data,the relationship between big data and medical informatics,and analyzes the reform of medical information education in the big data environment from the latest goals,contents and standards of medical information education.
2019 Vol. 26 (3): 185-187转191 [
Abstract
] (
86
)
HTML
(33 KB)
PDF
(0 KB) (
11
)
188
Treatment and thinking of multi-drug resistant infection in a patient with trauma
The article reviewed and discussed the treatment of multi-drug resistant infection in a patient with trauma.By reviewing the literature,multidisciplinary consultations,and looking for laboratory evidence,it suggests feasibility suggestions and assisted on the formulation of medication regimen.After admission,on the basis of clinical microbiological tests combined with the drug sensitivity test,and medication discussion from multidisciplinary professionals in the hospital,symptoms were improved and infections were controlled.Clinical pharmacists found the drug-resistant strains in time in the diagnosis and treatment process,and formulated individualized medication regimen,which ensures the drug safety,effectiveness and economy in patients.
2019 Vol. 26 (3): 188-191 [
Abstract
] (
80
)
HTML
(36 KB)
PDF
(0 KB) (
16
)
192
Analysis of 1 case of invasive pulmonary aspergillosis treated by Voriconazole combined with Amphotericin B
MENG Xiao1CHEN Wen-yin2LAO Hai-yan2▲
Analysis a successful case of Voriconazole combined with Amphotericin B in the treatment of invasive pulmonary aspergillosis(IPA),and through consulting literature to study the safety,efficacy and rationality of combination therapyin the treatment of IPA.By consulting literature,the efficacy of combination therapy better than monotherapy are still uncertain.Polyene or triazoles combined with echinocandins maybe synergies,but polyene combined with triazoles maybe antagonisms.Combination therapy maybe increase adverse reaction which related to drug dose and course and properties.In the absence of sufficient clinical evidence,combination therapy is not recommended for initial treatment but as remedial treatment.
2019 Vol. 26 (3): 192-195 [
Abstract
] (
84
)
HTML
(37 KB)
PDF
(0 KB) (
14
)
196
A case report and literature review about low fibrinogen hemorrhage af-ter percutaneous nephroscopy caused by Agkistrodon Snake Venom Hemocoagulase
HE Lin LAI Bing-wang
Minimally invasive percutaneous nephralithotomy lithotripsy (MPCNL)is a common method for the treatment of upper ureteral calculi and renal calculi.Postoperative bleeding is one of the most common and major complications,it is a complication caused by multiple factors.Commonly used conservative hemostatic schemes are bed rest,closed the renal fistula tube,balloon compression and drug hemostasis.This paper reports a case of a patient with ureteral calculi and renal calculi,who is treating by MPCNL and the operation was smooth.After the operation,Agkistrodon Snake Venom Hemocoagulase was used to treat the patients with hypoproteinemia and hemorrhage,and the patients developed hypofibrinogenemia and bleeding.Literature review was conducted in this case to explore the causes of postoperative hemorrhage after MPCNL,methods of hemostasis,matters needing attention and suggestions for the application of Agkistrodon Snake Venom Hemocoagulase.
2019 Vol. 26 (3): 196-198 [
Abstract
] (
86
)
HTML
(29 KB)
PDF
(0 KB) (
16
)
199
Clinical effect observation of pain nursing for patients with femoral neck fracture
CHEN Hong-manCHEN HongZHAO De-qun HUANG Hong-genZHOU MinXIA Lin-bo
Objective
To explore the effect of pain nursing on relieving pain symptoms of patients with femoral neck fracture after operation.
Methods
A total of 65 patiens with femoral neck fracture treated in our hospital from September 2015 to December 2017 were selected as the research objects,they were divided into observation group(n=33)and control group(n=32)according to random number table method.The control group was given routine nursing,while the observation group was given pain nursing on the basis of the control group.Number Rating Scale(NRS)was used to evaluate and compare the degree of pain,the pain relief,disappearance time,hospitalization time and total nursing satisfaction were compared between the two groups.
Results
The NRS score of the two groups was lower than that of 24 hours after operation,the difference was significant(P＜0.01).The NRS score of the observation group was lower than that of the control group at half and one month after operation,the differences were significant(P＜0.01).The pain relief,disappearance time and hospitalization time of patients in the observation group were shorter than those in the control group,the differences were statistically significant(P＜0.01).The total nursing satisfaction of patients in the observation group was higher than that of the control group,and the difference was statistically significant (P＜0.01).
Conclusion
Accurate pain nursing for patients with femoral neck fracture is helpful to reduce the degree of pain after operation,improve patient satisfaction,shorten hospitalization time and pain relief and disappearance time.
2019 Vol. 26 (3): 199-202 [
Abstract
] (
73
)
HTML
(35 KB)
PDF
(0 KB) (
8
)
203
Application effect of rapid rehabilitation surgical nursing in perioperative period of total knee arthroplasty
ZHANG Li-chun YU Long-ying ZHANG Xian-yu HUANG Hui-juan LI Jian FU Bao-fang WU Xiu-qin
Objective
To explore the application effect of rapid rehabilitation surgical nursing in perioperative period of total knee arthroplasty.
Methods
Sixty patients with total knee arthroplasty treated in our hospital from March 2017 to June 2018 were selected,they were randomly divided into experimental group and control group,with 30 cases in each group.The experimental group was given rapid rehabilitation nursing,while the control group was given routine nursing.Number score of pain (NRS)was used to evaluate and compare the degree of pain on the 1
st
,2
nd
and 3
rd
day after operation between the two groups.The knee joint function score (HSS)was used to compare the knee joint recovery of the two groups on the 3
rd
,7
th
and 10
th
day after operation.Hospitalization time and hospitalization expenses were compared between the two groups.
Results
The NRS scores of the experimental group were lower than those of the control group on the 1
st
,2
nd
and 3
rd
day after operation,and the HSS scores on the 3
rd
,7
th
and 10
th
day after operation were higher than those of the control group,the differences were statistically significant(P＜0.05).The hospitalization days in the experimental group were shorter than those in the control group,and the hospitalization expenses were significantly lower than those in the control group,the differences were statistically significant(P＜0.001).The total incidence of complications in the experimental group was significantly lower than that in the control group,the difference was significant(P＜0.05).
Conclusion
Rapid rehabilitation surgical nursing for patients undergoing total knee arthroplasty can relieve pain,shorten hospitalization time,reduce treatment costs and complications,and improve knee joint recovery and rehabilitation speed.
2019 Vol. 26 (3): 203-205 [
Abstract
] (
88
)
HTML
(33 KB)
PDF
(0 KB) (
14
)
206
Application effect of standardized hemostasis program for arteriovenous catheterization and extubation
CHENG Fen1ZHENG Xiao-fang1CHENG Li-mei1YU Ji-lan1FANG Jia1XIONG Ming-gui1XU Yue-yuan2
Objective
To explore the effect of standardized hemostasis scheme of arteriovenous catheterization and extubation in nurses.
Methods
A total of 260 patients who needed arterial catheterization and deep venous catheterization in Yingtan of Jiangxi Province from January 2017 to January 2018 were selected as the research subjects,they were divided into control group and research group according to random number table method,with 130 cases in each group.The control group was treated with routine hemostasis after extubation,and the research group was treated with improved hemostasis after extubation,the total satisfaction of nursing and the total incidence of complications after extubation were compared between the two groups.
Results
The total nursing satisfaction of the study group was significantly higher than that of the control group,the difference was significant(P＜0.05).The total incidence of complications after extubation in the study group was significantly lower than that in the control group,the difference was significant(P＜0.05).
Conclusion
The improved standard hemostasis method can reduce the probability of complications such as subcutaneous hematoma and hemorrhage after extubation,reduce patients′pain,improve patients′nursing satisfaction,and reduce the consumption of medical equipment and save resources.
2019 Vol. 26 (3): 206-208 [
Abstract
] (
83
)
HTML
(32 KB)
PDF
(0 KB) (
12
)
209
Application effect of respiratory training in patients after massive lung lavage
ZHONG Yan
Objective
To explore the application effect of respiratory training in patients after massive lung lavage.
Methods
A total of 44 patients with massive lung lavage successfully treated in our hospital from January 2015 to January 2018 were selected as the research objects,according to the different nursing methods,they were divided into observation group and control group,with 22 cases in each group,oxygen supply time was 4 h,patients in the control group were given routine nursing and natural breathing,while patients in the observation group were given breathing training mainly with lip contraction breathing.The nursing comfort,direct medical expenses,outpatient expenses,hospitalization expenses and total medical expenses were compared between the two groups.
Results
The comfort degree of patients in the observation group was higher than that in the control group,the direct medical expenses,outpatient expenses,hospitalization expenses and total medical expenses in the observation group were significantly lower than those in the control group,the differences were statistically significant(P＜0.05).
Conclusion
Respiratory training for functional exercises after large volume lung lavage is effective and worthy of popularization and application.
2019 Vol. 26 (3): 209-211 [
Abstract
] (
65
)
HTML
(31 KB)
PDF
(0 KB) (
10
)
215
Effect of Hospital-Community-Family integrated management on quality of life of elderly patients with chronic obstructive pulmonary disease
PAN Guang-huiWANG Jin-zhiHE Qiong
]
Objective
To explore the effect of Hospital-Community-Family integrated management on the quality of life of elderly patients with chronic obstructive pulmonary disease.
Methods
A total of 80 elderly patients with chronic obstructive pulmonary disease(COPD)admitted to our center and Jianshe Community Health Service Center From May to December 2016 were selected as the study subjects,they were divided into control group and research group by random number table method,with 40 cases in each group.The control group was given routine nursing intervention,while the research group was given Hospital-Community-Family integrated management on the basis of the control group.Blood gas index,lung function index and quality of life score were compared between the two groups.
Results
The arterial partial pressure of oxygen (PaO
2
)after implementation was higher than before,and the partial pressure of carbon dioxide(PaCO
2
)and pH were lower than before,the differences were statistically significant(P＜0.05).The PaO
2
of the study group was higher than that of the control group,and the PaCO
2
and pH of the study group were lower than that of the control group,the differences were statistically significant(P＜0.05).The forced expiratory volume(FEV
1
),forced vital capacity (FVC),the ratio of FEV
1
to FVC (FEV
1
%),peak expiratory flow (PEF)and FEV
1
/FVC were significantly higher in the two groups than before,the differences were statistically significant(P＜0.05).The pulmonary function indexes in the study group were higher than those in the control group,the differences were statistically significant(P＜0.05).The total average score of quality of life(TMS)and each dimension score of the two groups after implementation were lower than those before implementation,the differences were statistically significant(P＜0.05).The total average score of quality of life (TMS)and the scores of each dimension in the study group were lower than those in the control group,the differences were statistically significant(P＜0.05).
Conclusion
The application of Hospital-Community-Family integrated management in elderly patients with chronic obstructive pulmonary disease can effectively improve pulmonary function and blood gas index,and improve the quality of life of patients with high clinical value.
2019 Vol. 26 (3): 215-219 [
Abstract
] (
84
)
HTML
(47 KB)
PDF
(0 KB) (
15
)
220
Application effect of systematic rehabilitation nursing in humeral surgical neck fracture
XU Wan-yiHUO Li-weiWANG Guang-weiFAN Li-yun XIAO Can TAN Cheng-yi
Objective
To explore the application effect of systematic rehabilitation nursing in the treatment of humeral surgical neck fracture.
Methods
Eighty patients with humeral surgical neck fracture admitted to the emergency department of our hospital from June 2016 to May 2017 were randomly divided into routine nursing group and systematic rehabilitation nursing group,with 40 cases in each group.The routine nursing group was treated with manipulative reduction and modified over-shoulder splint fixation,after operation,the patients were treated with small splint fixation,postural nursing and dietary nursing.On this basis,the systematic rehabilitation nursing group cooperated with rehabilitation training guidance and psychological nursing.The shoulder Constant-Murley score (C-M score),fracture healing time and total nursing satisfaction were compared between the two groups before and after treatment.
Results
The C-M scores of the two groups after nursing were higher than those before nursing,and the C-M scores of the systemic rehabilitation nursing group after nursing were higher than those of the conventional nursing group,the differences were statistically significant(P＜0.05).The healing time of fracture in the systemic rehabilitation nursing group was(7.80±1.56)weeks,which was shorter than (9.68±1.33)weeks in the routine nursing group,the difference was statistically significant(P＜0.05).The nursing satisfaction rate of the systematic rehabilitation nursing group was 85.60%,which was higher than 78.50%of the routine nursing group,the difference was statistically significant(P＜0.05).
Conclusion
Systematic rehabilitation nursing for the treatment of humeral surgical neck fracture can effectively improve the clinical efficacy,shorten the healing time of fracture,and improve the patient's nursing satisfaction.
2019 Vol. 26 (3): 220-223 [
Abstract
] (
65
)
HTML
(39 KB)
PDF
(0 KB) (
13
)
224
Application effect of humanistic nursing care in the nursing of patients with kidney stone surgery
ZHANG Xin
Objective
To explore the application effect of humanistic nursing care in the nursing of patients with kidney stone surgery.
Methods
A total of 128 patients with renal calculi treated by operation in our hospital from December 2016 to February 2018 were selected as the research objects,according to the different nursing methods,they were divided into observation group and control group,with 64 cases in each group.The control group was given routine nursing intervention,while the observation group was given humanistic nursing care on the basis of routine nursing.Postoperative pain score,sleep efficiency score,incidence of complications and nursing satisfaction were compared between the two groups.
Results
The pain scores of the observation group at 12,24 and 48 hours after operation were significantly lower than those of the control group,the differences were statistically significant(P＜0.05).The sleep efficiency score and nursing satisfaction of the patients in the observation group were significantly higher than those in the control group,and the incidence of complications was significantly lower than that in the control group,the differences were statistically significant(P＜0.05).
Conclusion
The application of humanistic nursing care for patients with renal calculi can effectively relieve the pain after operation,improve the sleep quality and nursing satisfaction of patients,and reduce the occurrence of complications.It has clinical application value.
2019 Vol. 26 (3): 224-226 [
Abstract
] (
74
)
HTML
(31 KB)
PDF
(0 KB) (
17
)
227
Application effect of comfortable nursing in holistic nursing of hemodialysis room
LIU XiLUO Qian LI Xiao-qiong
[
Abstract
]
Objective
To explore the application effect of comfortable nursing in holistic nursing of hemodialysis room.
Methods
Sixty patients with chronic renal failure treated by blood purification in our hospital from February 2017 to February 2018 were selected as the research objects,they were randomly divided into observation group and control group by drawing lots,with 30 cases in each group.Two groups of patients were given holistic nursing,while the observation group was given comfortable nursing on the basis of the control group.Anxiety,depression and comfort scores were compared between the two groups.
Results
The anxiety score of the observation group was(5.6±0.3)points,lower than that of the control group(9.4±0.8)points,the difference was statistically significant(P＜0.05).The depression score of the observation group was(5.3±0.3)points,lower than that of the control group(10.1±1.1)points,the difference was statistically significant(P＜0.05).The comfort score of the observation group was(87.3±3.4)points,higher than that of the control group (74.2±2.6)points,the difference was statistically significant(P＜0.05).
Conclusion
Comfort nursing applied in holistic nursing of hemodialysis room can alleviate patients'negative emotions and improve patients'nursing comfort.It is worth popularizing and applying.
2019 Vol. 26 (3): 227-229 [
Abstract
] (
91
)
HTML
(31 KB)
PDF
(0 KB) (
13
)
230
Effect of nursing intervention on improving gastrointestinal function and reducing complications in patients undergoing laparoscopic cholecystectomy
FENG Li-yan HUANG Le-qingGUO Chun-ling HE Di-hua
Objective
To explore the effect of nursing intervention on improving gastrointestinal function and reducing complications in patients undergoing laparoscopic cholecystectomy.
Methods
Fifty patients undergoing laparoscopic cholecystectomy from March 2017 to March 2018 in our hospital were selected as research objects,and they were divided into the control group(25 cases)and the study group(25 cases)according to the random number table method.In the control group,patients were given the routine nursing,and in the study group,patients were given the nursing intervention on the basis of the control group.The gastrointestinal function recovery (recovery time of bowel sounds,anal exhaust time,anal defecation time,hospitalization time),postoperative complications,psychological status (self-rating depression scale [SDS],self-rating anxiety scale [SAS])and satisfaction with nursing were compared between the two groups.
Results
The recovery time of bowel sounds,anal exhaust time,anal defecation time and hospitalization time in the study group were shorter than those in the control group,and the differences were statistically significant(P＜0.05).The total incidence rate of postoperative complications in the study group was 16.00%,which was significantly lower than that in the control group accounting for 48.00%,and the difference was statistically significant(P＜0.05).There were no significant differences in SDS and SAS scores between the two groups before intervention (P＞0.05).The SDS and SAS scores of the two groups after intervention were lower than those before intervention,and the differences were statistically significant(P＜0.05).The SDS and SAS scores after intervention in the study group were lower than those in the control group,and the differences were statistically significant(P＜0.05).The total satisfaction of patients in the study group was 96.00%,which was significantly higher than that in the control group(60.00%),and the difference was statistically significant(P＜0.05).
Conclusion
Nursing intervention can significantly shorten the recovery time of gastrointestinal function in patients undergoing laparoscopic cholecystectomy,improve their psychological status and reduce the incidence of complications.Patients have higher nursing satisfaction.
2019 Vol. 26 (3): 230-232 [
Abstract
] (
83
)
HTML
(34 KB)
PDF
(0 KB) (
8
)
233
Application effect of intracranial pressure monitor to guide clinical nursing in patients with severe craniocerebral injury
HUANG Ping
Objective
To investigate the application effect of intracranial pressure monitor to guide clinical nursing in patients with severe craniocerebral injury.
Methods
A total of 42 patients with severe craniocerebral injury admitted to our hospital from January to October 2017 were selected as research subjects.The patients were divided into the conventional group(21 cases)and the experimental group(21 cases)according to the envelope random grouping method.In the conventional group,traditional nursing was used,while in the experimental group,intracranial pressure monitor guiding the clinical nursing was adopted.The mortality,rebleeding rate,disability rate,hospitalization time,and quality of life scores between the two groups were compared.
Results
The mortality,rebleeding rate and disability rate in the experimental group were lower than those in the conventional group,and the differences were statistically significant(P＜0.05).The hospitalization time in the experimental group was shorter than that in the conventional group,and the difference was statistically significant(P＜0.05).The score of life quality in the experimental group was higher than that in the conventional group,and the difference was statistically significant(P＜0.05).
Conclusion
The intracranial pressure monitor guiding the clinical nursing in patients with severe craniocerebral injury obtains a remarkable effect,which can reduce the disability rate and mortality of patients and improve the prognosis.
2019 Vol. 26 (3): 233-235 [
Abstract
] (
71
)
HTML
(32 KB)
PDF
(0 KB) (
13
)
236
Application effect of comprehensive nursing mode in the peripherally inserted central venous catheters in the children with acute leukemia
HUANG Yong-xian TANG Si-an LUO Xiao-wei
2019 Vol. 26 (3): 236-238 [
Abstract
] (
71
)
HTML
(30 KB)
PDF
(0 KB) (
14
)
239
Application effect of self-adhesive elastic bandage in the fixation of intravenous indwelling needle for newborns
CAO Juan CHEN Rong-yan GUO Juan PENG Li-yuan
Objective
To investigate the application effect of self-adhesive elastic bandage in the fixing intravenous indwelling needle for newborns.
Methods
A total of 240 cases of newborns who took intravenous indwelling needle in our hospital from February 2016 to June 2017 were selected as research subjects,and all of them were divided into the observation group and the control group according to the different fixation methods,with 120 cases in each group.Newborns in the observation group were given self-adhesive elastic bandage fixing method,and newborns in the control group were given routine fixing methods.Time of intravenous indwelling needle,adverse reactions and satisfaction of venous puncture care between the two groups were compared.
Results
The rate of indwelling needle retention time＞72 h in the observation group was 92.50%,which was significantly higher than that in the control group (71.67%),the indwelling time in the observation group was(5.73±0.94)d,which was significantly longer than that in the control group accounting for(2.75±0.75)d,and differences were statistically significant(P＜0.05).The total incidence rate of adverse reactions of intravenous indwelling needles in the observation group was 2.50%,which was significantly lower than that in the control group accounting for 28.33%,and the difference was statistically significant(P＜0.05).The total satisfaction of venipuncture care of the neonatal family in the observation group was 96.67%,which was higher than that in the control group(90.00%),and the difference was statistically significant(P＜0.05).
Conclusion
Self-adhesive elastic bandage in the fixation of intravenous indwelling needle for newborns can significantly prolong the fixing time,decrease the adverse reaction rates and improve satisfaction of venous puncture care,which is worthy of clinical promotion and application.
2019 Vol. 26 (3): 239-241转245 [
Abstract
] (
87
)
HTML
(35 KB)
PDF
(0 KB) (
12
)
242
Application effect of PDCA nursing mode in cesarean section of pernicious placenta previa
WU Jia-huiWAMG Min
Objective
To explore the application effect of PDCA nursing mode in cesarean section of pernicious placenta previa(PPP).
Methods
From June 2013 to June 2018,a total of 72 puerpera with PPP treated in our hospital were selected as study objects,and all of them underwent cesarean section combined with intervention.They were divided into the observation group and the control group according to the random number table method,with 36 cases in each group.The control group received routine nursing methods,and the observation group received PDCA nursing mode on the basis of the control group.The incidence of complications(postpartum hemorrhage,anemia and puerperal infection)between the two groups was compared.The self-rating anxiety scale(SAS)and the self-rating depression scale(SDS)were used to evaluate the emotional status before and after surgery between the two groups.
Reslults
All puerpera successfully completed cesarean section,and the degree of completion was 100%.The incidence rates of postpartum hemorrhage,anemia and puerperal infection in the observation group were lower those in the control group,and the differences were statistically significant(P＜0.05).There were no significant differences in the SAS and SDS scores between the two groups before surgery(P＞0.05).The SAS and SDS scores of the two groups after surgery were lower than those before surgery,and the differences were statistically significant(P＜0.05).The SAS and SDS scores after surgery in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).
Conclusions
PDCA cycle nursing mode can effectively improve the degree of surgical completion of puerpera with PPP,reduce the occurrence of postoperative complications,effectively promote postoperative recovery and improve mental state.
2019 Vol. 26 (3): 242-245 [
Abstract
] (
74
)
HTML
(35 KB)
PDF
(0 KB) (
15
)
246
Application effect of system nursing intervention in the nursing of elderly patients with hypertensive
DAI Yu1YANG Shu-ping2
Objective
To investigate the application effect of system nursing intervention in the nursing of elderly patients with hypertensive.
Methods
Altogether 100 elderly hypertensive patients admitted to our hospital from February 2016 to January 2018 were selected as subjects.They were divided into the control group(50 cases)and the observation group (50 cases)according to double-blind randomization method.Patients in the control group were given the routine nursing intervention,and patients in the observation group were given the system nursing intervention.Blood pressure,compliance behavior scores,and quality of life scores were compared between the two groups.
Results
There were no significant differences in diastolic blood pressure and systolic blood pressure between the two groups before intervention(P＞0.05).The diastolic blood pressure and systolic blood pressure of the two groups after 3 and 6 months of intervention were significantly lower than those before intervention,and the differences were statistically significant(P＜0.05).The diastolic blood pressure and systolic blood pressure in the observation group after 3 and 6 months of intervention were significantly lower than those in the control group,and the differences were statistically significant(P＜0.05).The scores of self-monitoring of blood pressure ([85.25±4.19]points),medication according to doctor′s advice([86.63±5.34]points),reasonable exercise([86.96±5.05]points),standardized diet([87.42±4.15]points),and control emotion ([89.56±1.10]points)in the observation group were respectively higher than those in the control group accounting for(76.52±5.12),(78.63±6.31),(77.52±5.28),(78.13±5.01),(79.56±2.16)points,and the differences were statistically significant(P＜0.05).The scores of general health status([86.63±2.15])points,physical pain([89.15±1.10]points),physiological operation([88.59±2.05]points),physiological function([87.49±1.16]points),emotions function([88.52±2.05]points),life vitality([87.46±3.14]points),mental health([88.59±2.01]points),and social function([87.49±2.33]points)of the observation group were respectively higher than those of the control group accounting for(79.52±3.15),(78.56±2.10),(77.52±3.16),(78.28±2.05),(77.96±3.31),(75.52±2.15),(76.64±2.31),(75.59±2.05)points,and the differences were statistically significant(P＜0.05).
Conclusion
System nursing intervention for elderly patients with hypertensive can effectively control blood pressure,correct their wrong life behaviors,and improve quality of life.
2019 Vol. 26 (3): 246-248转252 [
Abstract
] (
72
)
HTML
(36 KB)
PDF
(0 KB) (
15
)
249
Application effect of high quality nursing in patients undergoing debridement and suture in emergency department
ZHANG Wei
Objective
To investigate the application effect of high quality nursing in patients undergoing debridement and suture in emergency department.
Methods
A total of 42 patients in the emergency department who underwent debridement and suture treatment in our hospital from January to December 2017 were selected as subjects.According to the order of admission,they were divided into the reference group(21 cases)and the study group(21 cases).Patients in the reference group were given the routine nursing,and patients in the study group were given the high quality nursing.Preoperative and intraoperative systolic blood pressure,diastolic blood pressure,and heart rate were compared between the two groups.And preoperative and postoperative self-rating anxiety scale (SAS)score and self-rating depression scale (SDS)score were also compared between the two groups.
Results
There were no significant differences in preoperative systolic blood pressure,diastolic blood pressure,and heart rate between the two groups(P＞0.05).The intraoperative systolic blood pressure,diastolic blood pressure,and heart rate in the reference group were significantly higher than those in the preoperative period,and the differences were statistically significant(P＜0.05).There were no significant differences in systolic blood pressure,diastolic blood pressure and heart rate of the study group between preoperative and intraoperative (P＞0.05).The intraoperative systolic blood pressure,diastolic blood pressure,and heart rate in the study group were significantly lower than those in the reference group,and the differences were statistically significant(P＜0.05).There were no significant differences in SAS and SDS scores between the two groups before operation(P＞0.05).The SAS and SDS scores of the two groups after operation were lower than those before operation,and the differences were statistically significant(P＜0.05).The SAS and SDS scores after operation in the study group were lower than those in the reference group,and the differences were statistically significant(P＜0.05).The total satisfaction of patients in the study group was 100.00%,which was significantly higher than that in the reference group(80.95%),and the difference was statistically significant(P＜0.05).
Conclusion
High quality nursing for emergency debridement and suture patients will not have adverse effects on vital signs such as heart rate and blood pressure,and the stress response is small.It can also improve the psychological status of patients and enhance the satisfaction of nursing.The curative effect is determined and the popularization and application value is high.
2019 Vol. 26 (3): 249-252 [
Abstract
] (
100
)
HTML
(35 KB)
PDF
(0 KB) (
9
)
Copyright © Editorial Board of 中国当代医药
Supported by:
Beijing Magtech
