中国当代医药
Home
中文
中国当代医药
Forthcoming Articles
Current Issue
Archive
Advanced Search
Read Articles
Download Articles
Email Alert
Quick Search
Adv Search
2017 Vol. 24, No. 19
Published: 2017-07-08
4
Clinical，pathological and imaging analysis of 21 cases of gastrointestinal stromal tumors
REN Ping；DING Chang-qing；LIU Wen
ObjectiveTo investigate the clinical,pathological and images features of gastrointestinal stromal tumors (GIST).MethodsFrom March 2012 to December 2015,the complete data of 21 patients with GIST in our hospital were enrolled and the data of them were also analyzed retrospectively.Among them,10 males and 11 females,aged from 35 to 84 years,average age was 58.29 years.ResultsThe main symptoms were abdominal pain and abdominal discomfort(20 cases), gastrointestinal bleeding(6 cases)and abdominal mass(7 cases).The lesions located in the stomach (15 cases)and in the small intestine (6 cases).On the MSCT images,the tumor diameter was less than 5 cm in 17 cases(81%),the tumor border was clear in 18 cases(86%),the tumor border was not complete and were surrounded by the tissue infiltration in 3 cases(14%),the tumors were accompanied by vascular passage in 2 cases(9.5%).Immunohistochemical features:CD117 were positive in all the cases,the positive rate of CD34 was 81% (17/21)and the positive rate of DOG1 was 86%(18/21).ConclusionThe clinical manifestation of GIST is lack of specificity,MSCT imaging with certain characteristics features, and the high expression of DOG1,CD117 and CD34 is the important basis for diagnosis.
2017 Vol. 24 (19): 4-06转10 [
Abstract
] (
183
)
HTML
(39 KB)
PDF
(0 KB) (
36
)
7
Risk factors study of central retinal vein occlusion
FAN Li-min；YANG Bo；JI Qing；LI Nai-yang
ObjectiveTo investigate the risk factors of central retinal vein occlusion.MethodsThe clinical data of 258 cases of outpatients and inpatients in our hospital from January 2013 to December 2016 were retrospectively analyzed in this study.Among them,there were 132 cases of central retinal vein occlusion(the study group),and 126 cases was non central retinal vein occlusion(the control group).The level of blood glucose,blood lipid(triglyceride,cholesterol,high density lipoprotein,low density lipoprotein),platelet count,fibrinogen and blood D-dimer in the two groups was compared.ResultsUnivariate analysis showed that there was significant difference in the level of hypertension,diabetes,smoking and D-dimer between the two groups(P＜0.05).After adjusting for age,smoking and other factors,Logistic regression analysis showed that the hypertension,diabetes and D-dimer levels were independent risk factors for central retinal vein occlusion(D-dimer:OR=1.31,95%CI:1.028-1.894,P=0.041;hypertension:OR=1.24,95%CI:1.094-1.672,P=0.039;diabetes:OR=1.37, 95%CI:1.128-1.933,P=0.046).The level of D-dimer was significantly different between ischemic and non-ischemic central retinal vein occlusion(P＜0.05).ConclusionThe increase of D-dimer,hypertension and diabetes are independent risks factor for central retinal vein occlusion.D-dimer,hypertension and diabetes may be the predictor of central retinal vein occlusion.The level of D-dimer may be related to ischemic central retinal vein occlusion.
2017 Vol. 24 (19): 7-10 [
Abstract
] (
184
)
HTML
(39 KB)
PDF
(0 KB) (
37
)
11
The pharmaceutical application research progress of industrial production of Human serum albumin
WANG Zong-tai；MA Ning-ning
Human serum albumin（HAS）is the most abundant in human plasma，is a protein，in the plasma total protein accounted for about 60%of the proportion of physiological function is not only important，but also more，but also the pharmaceutical industry The most important of a kind of raw auxiliary materials.Most of the HSA sold in the current market is extracted with human plasma，but the risk of blood is greater，which makes the recombinant human serum albumin（rHSA）a preferred alternative to HSA.The pharmaceutical application research progress of industrial production of rHSA were reviewed in this article.
2017 Vol. 24 (19): 11-14 [
Abstract
] (
195
)
HTML
(41 KB)
PDF
(0 KB) (
55
)
15
Correlation study ofbetween oxidativestressrelated factors,tumor necrosis factor and disease activity of psoriasis vulgaris
MAI Li-li；LUO Xiao-yuan；HE Hai-chun；ZHENG Li-xiong
ObjectiveTo investigate the correlation between oxidative stress related factors,tumor necrosis factor(TNF) and and disease activity of psoriasis vulgaris.MethodsFrom July 2014 to June 2015,46 cases with psoriasis vulgaris treated in the Second People′s Hospital of Longgang District in Shenzhen City were selected and according to the psoriasis area and severity index (PASI),the patients were divided into the mild to moderate group (29 cases)and severe group(17 cases),the other 30 cases of normal controls(healthy control group).Serum total antioxidant capacity(T-AOC) level,superoxide dismutase (SOD),catalase (CAT),glutathione peroxidase (GSH-Px),tumor necrosis factor(TNF-α), osteopontin (OPN)expression level were detected.ResultsSerum T-AOC,SOD and GSH-Px level in the mild to moderate group and severe group were significantly lower than the healthy control group,the serum CAT level was significantly higher than that of the control group(P＜0.01),serum T-AOC,SOD,GSH-Px in the severe group was significantly lower than that of the mild to moderate group,the serum CAT level was significantly higher than that of the mild to moderate group (P＜0.01,P＜0.05).TNF-α and OPN level in the mild to moderate group and severe group were significantly higher than those in healthy control group(P＜0.01),serum TNF-α and OPN level in the severe group were higher than those in the mild to moderate group(P＜0.01,P＜0.05).PASI grading was negatively correlated with T-AOC,SOD,GSH-Px classification(P＜0.05);and was positively correlated with CAT,TNF-α,OPN (P＜0.05).ConclusionThe oxidative stress level and inflammatory reaction are closely related to the severity of psoriasis vulgaris,and serum T-AOC,SOD,CAT,GSH-Px, TNF-α,OPN can be used as a reference index to evaluate the disease severity and prevention of psoriasis vulgaris.
2017 Vol. 24 (19): 15-17 [
Abstract
] (
195
)
HTML
(35 KB)
PDF
(0 KB) (
40
)
18
Short-term efficacy of interventional therapy in type 2 diabetic patients with superficial femoral artery occlusion
TANG Hai-tao；ZHOU Yu-bin；WU Dan-ming；WANG Cheng-gang；YI Wei
ObjectiveTo explore the short-term efficacy of interventional therapy in patients with type 2 diabetes mellitus complicated with superficial femoral artery occlusion.Methods117 type 2 diabetes mellitus patients with superficial arterial occlusion were selected in our research,who
received：
interventional therapy in our hospital from June 2014 to May 2016.The levels of ABI and TBI were compared before and after operations and the vascular patency rate was measured at the 1st,3rd and 6th month.ResultsThe levels of ABI and TBI were(0.98±1.13)and(0.62±0.11)respectively significantly higher than those before operation[(0.38±0.28),(0.25±0.03)](P＜0.05).The vascular patency rate of patients were 94.87%,87.18%,64.96%at the 1st,3rd and 6th month respectively.ConclusionInterventional therapy possesses the advantage of minimally invasive and our research shows an ideal short-term efficacy,thus it provides a reliable option for type 2 diabetes patients with superficial femoral artery occlusion.
2017 Vol. 24 (19): 18-20 [
Abstract
] (
158
)
HTML
(32 KB)
PDF
(0 KB) (
43
)
21
Clinical effect analysis of automatic hemorrhoid ligation in the treatment of hemorrhoid bleeding
CHEN Chu-hang； QIU Hai-min ；ZHU Da-kang
ObjectiveTo investigate the clinical effect of automatic hemorrhoid ligation in the treatment of hemorrhoid bleeding.Methods96 patients with hemorrhoid bleeding treated in our hospital from March 2015 to March 2017 were selected and randomly divided into observation group and control group,and each group contained 48 patients.Observation group
received：
automatic ligation of hemorrhoids while control group received traditiona lligation.The treatment effect,average operation time and the incidence of complication were compared between the two groups.ResultsThe total effective rate of the observation group(93.7%)was significantly higher than that of the control group(68.7%),while the average operation time[(7.1±1.4)min]was significantly lower than that of the control group[(10.6±1.1)min],and the tota lincidence of complications(4.2%)was significantly lower than that of the control group(25.0%),and the differences were statistically significant(P＜0.05).ConclusionThe effect of automatic hemorrhoid ligation in the treatment of hemorrhoids bleeding is good,the operation time is short and the complications are few,so it can be popularized and applied in clinic.
2017 Vol. 24 (19): 21-23 [
Abstract
] (
177
)
HTML
(32 KB)
PDF
(0 KB) (
43
)
24
Effect comparison of laparoscopic cholecystectomy in emergency and open cholecystectomy treating acute cholecystitis
CHEN Chu-qun
ObjectiveTo discuss the effect of laparoscopic cholecystectomy in emergency and open cholecystectomy treating acute cholecystitis.MethodsClinical data of 120 cases with acute cholecystitis treated in general surgery department of our hospital from January 2013 to December 2016 were analyzed and they were divided into two groups by different operation methods:open group(open cholecystectomy in emergency,n=60)and laparoscopic group(laparoscopic cholecystectomy in emergency,n=60).The treatment condition,the total effective rate,the incidence of complications after operation in patients between the two groups were compared.ResultsThe operation time[(31.7±5.9)min],stomach intestine functional recovery time[(18.1±2.9)h]and hospital stays[(4.5±1.0)d]in laparoscopic group were shorter than those of open group[(63.5±10.2)min,(28.4±3.6)h,(9.5±3.4)d],intraoperatve blood soss[(55.9±7.5)ml]was fewer than that of control group[(136.8±16.7)ml](P＜0.05).The total effective rate(100%)was higher than that of control group(80%),the incidence of complications after operation in laparoscopic group(6.7%)was lower than that of open group(20.0%),and the differences were statistical significance(P＜0.05).ConclusionThe injury of laparoscopic cholecystectomy in emergency treating acute cholecystitis is little,recovery is good,prognosis is good.
2017 Vol. 24 (19): 24-26 [
Abstract
] (
191
)
HTML
(32 KB)
PDF
(0 KB) (
54
)
27
Clinical observation of Caspofungin treating neutrophil deficiency combined with deep fungal infection after chemotherapy used for malignant hematologic disease
ZHENG Fang-ying
ObjectiveTo analyze the clinical effect of Caspofungin treating neutrophil deficiency combined with deep fungal infection after chemotherapy used for malignant hematologic disease.Methods69 patients with neutrophil deficiency combined with deep fungal infection after chemotherapy used for malignant hematologic disease treated in our hospital from December 2013 to November 2015 were selected and they were divided into experimental group(37 cases) and control group(32 cases)according to order of admission.Control group was treated with Amphotericin B,while experimental group was treated with Caspofungin.The therapeutic effect between the two groups was compared.Resultsthe total effective rate was 86.5%in experimental group and it was 81.2%in control group,and there was no significant difference between the two groups(P＞0.05).The total incidence rate of adverse reaction of experimental group was 8.1%,which was significantly lower than that of the control group(21.8%),and the difference was statistically significant(P＜0.05).ConclusionCaspofungin
received：
in early stage treating neutrophil deficiency combined with deep fungal infection after chemotherapy used for malignant hematologic disease can obtain satisfactory effect,and adverse reaction is few,and it has the value of popularization.
2017 Vol. 24 (19): 27-29 [
Abstract
] (
181
)
HTML
(31 KB)
PDF
(0 KB) (
69
)
30
Clinical application analysis of botulinum toxin type A in cosmetic surgery
HAN Ling
ObjectiveTo explore the clinical efficacy of botulinum toxin type A combined with non stripped 1550 nm dot matrix laser and Hyaluronic Acid improving facial wrinkles.Methods114 patients given wrinkle removal in our hospital from March 2014 to August 2016 were collected and they were divided into the three groups according to the random number table method:laser combined treatment group,Hyaluronic Acid combined treatment group and injection control group.The laser treatment group was injected with botulinum toxin type A and given 1550 nm dot matrix laser of three times after 2 weeks,each time had a interval of 4 weeks.Hyaluronic Acid combined treatment group was treated with different levels of subcutaneous injection of Hyaluronic Acid,then botulinum toxin type A was injected.The injection control group was only injected botulinum toxin A.VISIA skin tester was used to evaluate the treatment effect and facial state of patients was recorded after 4,12,24 weeks.ResultsThe difference of VISIA score among the three groups before and after treatment was statistically significant(P＜0.05).There was a statistical difference of VISIA score between the Hyaluronic Acid combined treatment group and injection control group(P=0.037),and there was no statistical difference of VISIA score between the laser combined treatment group and injection control group(P=0.758).After 4,12,24 weeks operation,there was a statistical difference of the effective rate between the Hyaluronic Acid combined treatment group (92.1%,86.8%,78.9%)and injection control group(86.8%,81.6%,71.1%),and there was a statistical difference of the effective rate between the Hyaluronic Acid combined treatment group(86.8%,81.6%)and injection control group(81.6%, 71.1%)(P＜0.05).ConclusionBotulinum toxin type A can effectively and safely reduce facial wrinkles,and its effect was better combined with dot matrix laser and Hyaluronic Acid.
2017 Vol. 24 (19): 30-32 [
Abstract
] (
179
)
HTML
(37 KB)
PDF
(0 KB) (
64
)
33
Study on the correlation between the gene polymorphism of heme oxygenase-1 promoter and the coronary heart disease and the quality of life after stenting
ZHANG Ying-xi；CHEN Jun-yu；CHEN Rong-song；CHEN Song-ming；YANG Bao-jun
ObjectiveTo study the correlation between the gene polymorphism of heme oxygenase-1(HO-1)promoter and the quality of life after stenting in the patients with coronary heart disease.Methods58 patients with coronary heart disease who were admitted to our hospital from August 2015 to August 2016 were clinically enrolled.They were assigned to the coronary heart disease group.All patients were given the intervention of stenting.Another 58 volunteers who were given physical examination in our hospital during the same period of time were selected as the control group.The distribution of HO-1 promoter gene polymorphism was observed in the two groups of subjects.The quality of life was observed in both groups,and the correlation between gene polymorphism of HO-1 promoter and the patients with coronary heart disease was analyzed.ResultsThere were significant differences in the distribution of SS,SL,LL genotypes and S,L alleles between the patients in the coronary heart disease group and the control group(P＜0.05);while the distribution of long and short genotypes was not different(P＞0.05).The scores of QOL and ADL in the coronary heart disease group were significantly lower than those in the control group(P＜0.05).SS,SL genotypes and S allele were significantly negatively correlated with the quality of life of patients with coronary heart disease(P＜0.05);LL genotype and L allele were positively correlated with the quality of life of patients with coronary heart disease(P＜0.05).ConclusionThe quality of life of patients with coronary heart disease after stenting is closely correlated to the HO-1 promoter gene polymorphism.Patients carrying with SS,SL genotypes and S allele generally have a better quality of life,while the patients carrying with LL genotype and L allele have a poorer quality of life.
2017 Vol. 24 (19): 33-35 [
Abstract
] (
135
)
HTML
(37 KB)
PDF
(0 KB) (
45
)
36
Influence of Shensong Yangxin Capsule combined with low-dose Metoprolol Succinate Sustained-release Tablets on arrhythmia and inflammatory factors after percutaneous coronary intervention
YE Shao-qiang；JIANG Shou-tao；HUANG Rui-na
ObjectiveTo observe the effect of Shensong Yangxin Capsule combined with low-dose Metoprolol Succinate Sustained-release Tablets on arrhythmia and inflammatory factors after percutaneous coronary intervention(PCI).MethodsFrom May 2013 to May 2016，134 patients with arrhythmia after PCI in Guangzhou Traditional Chinese and Western Medicine Hospital and the Affiliated Hospital of Guangdong Medical University were divided into three groups by a random number table including Metoprolol Succinate Sustained Release Tablet group(group A;n=46;47.5 mg each time，and once per day)，Shensong Yangxin Capsule group(group B;n=45;3 capsules each time and thrice per day)，and Shensong Yangxin Capsule combined with low-dose Metoprolol Succinate Sustained Release Tablets(group C;n=43;3 Shensong Yangxin capsules each time and three times per day together with 23.75 mg Metoprolol Succinate Sustained release tablet，once per day).The follow-up visits were lasted for 3 months.The incidence of arrhythmia and inflammatory factor levels including high-sensitivity C-reactive protein(hs-CRP)，tumor necrosis factor-α(TNF-α)and interleukin-6 (IL-6)before and after therapy were compared.ResultsCompared with prior treatment，the incidence of arrhythmia and inflammatory factor levels after surgery among three groups were all lower(P＜0.05).By inter-group comparisons，the incidence of arrhythmia was lowest in group C(P＜0.05)，and the levels of hs-CRP，TNF-α and IL-6 in group C were significantly decreased(P＜0.05).ConclusionCombination of Shensong Yangxin Capsule and low-dose of Metoprolol Succinate Sustained Release Tablets can effectively reduce the incidence of arrhythmia after PCI and decrease the inflammatory response.
2017 Vol. 24 (19): 36-38转43 [
Abstract
] (
187
)
HTML
(37 KB)
PDF
(0 KB) (
63
)
39
Impact of Metoprolol combined with Atorvastatin on heart rate variability and long-term effect in patients with heart failure
XIE Yang；ZHOU Hao-yue；HUANG Wei-peng； LIN Yu-peng ；ZHANG Hua-di
ObjectiveTo discuss the impact of Metoprolol combined with Atorvastatin on heart rate variability and long-term effect in patients with heart failure.MethodsA case-control study design was used.Patients with chronic heart failure treated in our hospital from January 2011 to December 2012 were retrospectively selected according to the certain entry criteria.The case group was patients matching the entry criteria and given Atorvastatin treatment and the control group was patients matching the entry criteria and had no Atorvastatin treatment.The timing of initiation of statin use was used as a basic matched condition for including control(within 1 weeks of admission),while matching age and sex.120 patients were included with 60 cases in case group and 60 cases in control group.Standardized treatment including Metoprolol of CHF was used in each group.After 12-month follow-up,each index change of heart function and heart rate variability before treatment and after 6 months treatment in patients of the two groups were observed.Before treatment and after 12 months treatment,SF-36 scale was used to evaluate the quality of life score in patients of the two groups.The survival state and adverse reactions of 6 and 12 months during treatment were compared between the two groups.ResultsLVEF was(49.38±6.42)%in case group after 6-months treatment,which was higher thanthat in control group[(43.34±6.18)%],and the difference was statistically significant(P＜0.05).LVEDD and LVESD were (60.39±3.02)mm and (41.25±5.68)mm in case group after 6-months treatment,which were lower than that in control group [(63.94±2.67),(46.73±5.76)mm]and the difference was statistically significant(P＜0.05).SDNN,SDANN,rMSSD and PNN50 were(116.79±20.54)ms,(108.22±13.04)ms,(22.74±6.12)ms and(12.76±4.83)%in case group after 6-months treatment,which were all higher than that in control group [(92.38±18.72)ms,(92.31±12.58)ms,(15.73±5.78)ms,(8.29± 2.74)%]and the difference was statistically significant(P＜0.05).After 12 months,physiological function,physiological function,body pain,general health,vitality,social function,emotional function and mental health score of 8 dimensions in patients of case group patients were higher than those in control group,there was significant difference between the two groups(P＜0.05).The survival rate of 12 month in case group was 88.33%,which was higher than that(73.33%)of control group,but the difference between the two groups was not statistically significant(P＞0.05).Conclusion Metoprolol combined with atorvastatin can effectively improve cardiac function in patients with CHF,improve the heart rate variability,but also can improve the quality of life of patients,and it is safe and effective,although the survival rate of patients with has no obvious improvement,but in clinical practice,patient status given individual analysis to conduct the discretionary use.
2017 Vol. 24 (19): 39-43 [
Abstract
] (
194
)
HTML
(45 KB)
PDF
(0 KB) (
64
)
44
The effect of CT three-dimensional reconstruction in the treatment of HICH with minimally invasive intracranial hematoma puncture and drainage
PENG Hai-ling；FANG Xiao-hong；XU Wei-guang
ObjectiveTo analyze the clinical effect of minimally invasive intracranial hematoma puncture and drainage in the treatment of HICH with three-dimensional reconstruction of CT.Methods176 cases of HICH in our hospital from January 2012 to June 2016 were selected and divided into simple CT positioning patients(control group)and spiral CT localization patients(observation group)according to the three-dimensional reconstruction,there were 89 cases in the control group and the other in the observation group (n=87).The effect of two methods on the localization of intracranial hematoma,appropriate puncture point using hose puncture,drainage efficiency were observed.ResultsThe effective rate in patients of observation group(93.10%)was higher than that in patients of control group(86.52%)(P＜0.05).The success rate of observation group was 93.10%,which was significantly higher than that of control group (86.52%,P＜0.05).The postoperative complications were compared between the two groups,the patients with spiral CT localization,the rate of postoperative rebleeding(6.90%)was significantly lower than that of the patients with simple CT(13.80%)(P＜0.05).ConclusionApplication of CT 3D reconstruction in soft channel minimally invasive intracranial hematoma drainage in patients with HICH,the clinical effect of spiral CT 3D reconstruction method is obviously better than that of simple CT three-dimensional reconstruction,the accuracy of positioning is high,the patient′s postoperative complications are less, and can significantly improve the prognosis of patients.
2017 Vol. 24 (19): 44-46 [
Abstract
] (
178
)
HTML
(33 KB)
PDF
(0 KB) (
36
)
47
Clinical study on the treatment of primary trigeminal neuralgia by retrosigmoid approach
LUO Fei；YANG Rui-jin
ObjectiveTo investigate the clinical effect of retrosigmoid approach for the treatment of primary trigeminal neuralgia.Methods84 patients with primary trigeminal neuralgia in our hospital from December 2014 to December 2016 were randomly divided into the observation group(n=42)and the control group(n=42),the observation group was treated with posterior decompression via retrosigmoid approach,the control group was treated with percutaneous semilunar ganglion radiofrequency thermocoagulation,the therapeutic effect,postoperative complications and recurrence were compared between the two groups.ResultsThe total effective rate of the observation group was 88.09%,which was higher than that of the control group(66.67%),the incidence of postoperative complications(23.80%)was less than that of the control group (47.61%),the cure rate and recurrence after operation were significantly better than those of the control group,and the differences were statistically significant(P＜0.05）.ConclusionThe treatment of primary trigeminal neuralgia by retrosigmoid approach has significant curative effect.It has high cure rate,less recurrence and less postoperative complications.It is worthy of clinical promotion and application.
2017 Vol. 24 (19): 47-49转77 [
Abstract
] (
150
)
HTML
(36 KB)
PDF
(0 KB) (
44
)
50
Research on serum correlation of neurotrophin and clinical symptoms in first episode Schizophrenia
WAN Jing ；HUANG Cai-ying ；XUE Kun-xi；HU Jing； PING Jun-jiao； DU Bao-guo
ObjectiveTo study the correlation among brain-derived neurotrophic factor(BDNF),nerve gowth factor(NGF) and the clinical manifestation in first episode schizophrenia.MethodsDouble antibody sandwich enzyme-linked immunosorbentassay(ELISA)was adopted to quantitate BDNF and NGF serum levels of 38 first episode schizophrenic patients hospitalized in Department of Early Intervention of our Hospital from September 2015 to November 2016 and 50 healthy people for medical examinations.Positive and negative syndrome scale(PANSS)was used to evaluate the clinical state of the patients.BNDF and NGF serum concentration of the two groups was analyzed.Pearson correlative analysis was adopted to analyze the correlation between BDNF,NGF serum concentrations and PANSS scores in patient group.ResultsNo statistical differences was found in age,gender or years of education in two groups.Lower BDNF serum levels[(2913.19± 638.30)pg/ml]were found(t=4.465,P＜0.01)in the patient group than in healthy subjects[(355.3±685.98)pg/ml].Lower NGF serum concentrations[(36.96±8.28)pg/ml]were found(t=3.450，P＜0.01)in the patient group than in the controls[(44.30± 10.94)pg/ml].BDNF serum concentrations and PANSS scores were not correlated in patient group.There were no correlations found among,PANSS-positive scores,PANSS-general scores and PANSS-Total scores in the patient group,however, NGF serum levels were negatively related to PANSS-negtive scores in patient group(r=-0.256,P＜0.05).BDNF was found positively related to NGF serum levels(r=0.378,P＜0.01).ConclusionCognitive impairments occurred in schizophrenic patients,and NGF in the serum may impact growth and development of nervous system.BDNF and NGF may play similar role on nosogenesis of schizophrenia.
2017 Vol. 24 (19): 50-52 [
Abstract
] (
193
)
HTML
(31 KB)
PDF
(0 KB) (
36
)
53
Effect observation of hybrid renal replacement therapy in the treatment ofelderly patientswith systemicinflammatory responsesyndrome accompanied with acute kidney injury
CUI Meng-bi；WANG Song；HU Shan-shan；SU Feng-xian；ZHA Yan
ObjectiveTo investigate the clinical efficacy of hybrid renal replacement therapy in the treatment of elderly patients with systemic inflammatory response syndrome accompanied with acute kidney injury.MethodsFrom May 2012 to May 2014,38 cases of systemic inflammatory response syndrome accompanied with severe acute kidney injury in elderly patients with severe pneumonia,heart disease and cerebrovascular accident were selected and divided into the HRRT group(20 cases)and the control group(18 cases)according to the different treatment methods.The HRRT group was given routine treatment combined with continuous veno venous hemofiltration plus plasma exchange(CVVHDF+PE),the control group was given routine treatment.The APACHEⅡscore,renal function,blood gas analysis,inflammatory factors and immune function index(CD4+,CD8+,CD4+/CD8+)and the half year survival rate in the two groups were compared.ResultsThe levels of CD8+,IL-10,IL-6 and TNF-α in the HRRT group after treatment was lower than that before treatment and in the control group after treatment,and the levels of CD4+,CD4+/CD8+in the HRRT group after treatment was higher than that before treatment and the control group after treatment,with significant difference(P＜0.05).The levels of pH and HCO3-in the HRRT group after treatment was higher than that before treatment and in the control group after treatment,the level of PCO2,serum Cr,serum BUN and APACHEⅡ score in the HRRTgroup after treatment was lower than that before treatment and in the control group after treatment,with significant difference(P＜0.05).The half year survival rate of the HRRT group was 85.0%,which was higher than 44.4%of the control group,with significant difference(P＜0.05).ConclusionFor systemic inflammatory response syndrome complicated with acute kidney injury due to severe pneumonia,heart disease and cerebrovascular accident syndrome,on the basis of routine treatment,early application of HRRT can effectively remove various toxins and inflammatory mediators,correct the imbalance of acid-base balance,improve the immunosuppressive status and clinical symptoms,and ultimately improve the success rate of treatment of elderly patients.
2017 Vol. 24 (19): 53-56 [
Abstract
] (
198
)
HTML
(41 KB)
PDF
(0 KB) (
36
)
57
Effect comparison of flexible ureteroscopy lithotripsy and percutaneous nephrolithotomy for renal calculi combined with complicated urinary tract infection
XIE Qing-ling； LI Xun ；HE Yong-zhong ；LI Tian ；XU Gui-bin
ObjectiveTo compare the efficacy of flexible ureteroscopic lithotripsy and percutaneous nephrolithotomyin the treatment of renal calculi combined with complicated urinary tract infection.MethodsFrom February 2014 to February 2017,110 cases of renal calculi combined with complicated urinary tract infection in our hospital were selected and randomly divided into the observation group and the control group,55 cases in each group.The observation group was treated with flexible ureteroscope lithotripsy,and the control group was treated with percutaneous nephrolithotomy. The intraoperative blood loss,operation time,hospitalization time,stone clearance rate,infection reduction rate,the incidence rate of complication and the change of T lymphocyte subsets were compared between the two groups.ResultsThe amount of intraoperative blood loss in the observation group was less than that in the control group,and the operation time and hospitalization time in the observation group was shorter than that of the control group,with significant difference (P＜0.05).There was no significant difference between the two groups in the rate of stone clearance and the rate of infection remission (P＞0.05).The incidence rate of postoperative complications in the observation group was 3.64%, which was significantly lower than 16.36%in the control group,with significant difference(P＜0.05).There was no significant difference between the two groups before and after the operation in the level of CD8+(P＞0.05).There was no significant difference between before and after the operation in the observation group in the levels of CD3+,CD4+and CD4+/ CD8+(P＞0.05).The levels of CD3+,CD4+and CD4+/CD8+in the control group after the operation at 1 and 24 h was significantly lower than that before the operation,with significant difference (P＜0.05).The level of CD3+,CD4+and CD4+/ CD8+was recovered until 72 after operation.ConclusionCompared with percutaneous nephrolithotomy,flexible ureteroscopic lithotripsy has no significant advantage in the rate of stone clearance and the remission rate of infection,but the complication rate is lower and the injury is less.
2017 Vol. 24 (19): 57-60 [
Abstract
] (
201
)
HTML
(46 KB)
PDF
(0 KB) (
46
)
61
Evaluation of efficacy of transurethral plasmakinetic resection of prostate of benign prostatic hyperplasia
JIANG Hong-tao1QIN Guo-qing；LIU Luo-gen；ZHANG Yun-sheng；ZHOU Ming-shu；ZHANG Hong；WANG Yi
ObjectiveTo investigate the effects of transurethral resection of prostate on intraoperative blood loss，therapeutic effect and postoperative complications of patients with benign prostatic hyperplasia(BPH).MethodsThe clinical data of 80 cases of patients with benign prostatic hyperplasia in our hospital from January 2015 to January 2017 were retrospectively analyzed，these patients were divided into TURP group(study group，n=40)and open surgical gland resection group（control group，n=40)two groups according to the treatment methods，the operation time，intraoperative blood loss，indwelling catheter time，IPSS scores，Qmax，RUV，QOL scores，therapeutic effects，postoperative complications of the two groups were statistically analyzed.ResultsThe operation time，indwelling catheter time of the study group were significantly shorter(P＜0.05)，the intraoperative blood loss was significantly less(P＜0.05)，the IPSS score，RUV were significantly lower(P＜0.05)，the Qmax，QOL score were significantly higher(P＜0.05)，the total treatment efficiency [92.5%(37/40)]was significantly higher than that of the control group[75.0%(30/40)](P＜0.05)，the postoperative complications rate[17.5%(7/40)]was significantly lower than that of the control group[35.0%(14/40)](P＜0.05).ConclusionTransurethral resection of prostate is more effective in reducing the intraoperative blood loss，improving the therapeutic effect，reduce the postoperative complications of patients with benign prostatic hyperplasia than open surgical gland resection.
2017 Vol. 24 (19): 61-64 [
Abstract
] (
176
)
HTML
(42 KB)
PDF
(0 KB) (
40
)
65
Effect of suspended traction bed in the treatment of lumbar disc herniation
WANG Zhi-juan；GUO Yong；JIA Guo-qing
ObjectiveTo investigate the effect of suspended traction bed in the treatment of lumbar disc herniation.Methods130 patients with lumbar disc herniation treated in our hospital from January 2013 to December 2014 were selected and randomly divided into the treatment group(n=67)and the control group(n=63).The treatment group was treated with suspended traction bed,while the control group was treated with traditional technique.The effects of the two groups were compared.ResultsThe total scores of symptoms and daily activities in the two groups were significantly lower than those before treatment,with significant difference(P＜0.05).The total scores of symptoms and daily activities after treatment in the treatment group were lower than those in the control group after treatment,with significant difference(P＜0.05).The symptom score,daily activity score and total score of the treatment group after discharge at 1 year were significantly lower than those of the control group,with significant difference(P＜0.05).ConclusionThe long-term effect of the treatment of lumbar disc herniation by suspended traction bed is better than that of not use suspended traction bed.
2017 Vol. 24 (19): 65-67 [
Abstract
] (
157
)
HTML
(37 KB)
PDF
(0 KB) (
33
)
68
Etiological study and preventive measures of wound infection in patients with open fracture of tibia and fibula
YANG Zheng-yan； LI Zong-ze ；LIU Wen-jun； HU Hai-quan
ObjectiveTo investigate the etiological study and preventive measures of wound infection in patients with open fracture of tibia and fibula so as to provide valuable reference information for future clinical work.MethodsThe clinical data of 56 patients with open fractures of tibia and fibula who were treated from July 2014 to January 2016 in our hospital was collected and their infection conditions were statistically analyzed;then,isolation,identification and drug susceptibility test of pathogens were performed to summarize the targeted intervention measures.ResultsAmong 56 patients that were involved in the survey,there were 4 cases of wound infections,with the infection rate accounting for 7.14%; according to the pathogen detection results,7 strains of pathogens were isolated,including Gram-positive and Gramnegative bacteria,the proportion of the former was higher than that of the latter(P＜0.05).Staphylococcus aureus and Coagulase negative staphylococci had low drug resistance on clinically commonly-used antibiotics such as Vancomycin; Escherichia coli and Pseudomonas aeruginosa had relatively low drug resistance on Cefoperazone/Sulbactam.ConclusionPatients with open fractures of tibia and fibula have low incidence but great risk of wound infections,mostly with Gram-positive bacteria as the pathogens.In the future clinical work,great attention should be paid to strengthened aseptic operation,close monitoring of drug-resistant bacteria and rational use of antibiotics so as to reduce the incidence of wound infections and to improve the clinical therapeutic effect and the quality of clinical medical care.
2017 Vol. 24 (19): 68-70 [
Abstract
] (
150
)
HTML
(33 KB)
PDF
(0 KB) (
40
)
71
Clinical effect observation of percutaneous vertebroplasty and percutaneous kyphoplasty in the treatment of osteoporotic thoracolumbar vertebral compression fractures
CHEN Xu-hong；WANG Ju；LIU Yang-can；XIE Shi-long；YANG Lin
ObjectiveTo explore the clinical efficacy of percutanous vertebroplasty(PVP)and percutanous Kyphoplasty (PKP)in patients with osteoporotic thoracolumbar vertebral compression fractures.MethodsFrom October 2015 to October 2016,120 patients with osteoporotic thoracolumbar vertebral compression fractures were enrolled in this study,and were treated with surgical treatment,and all patients were divided into the PVP group(n=60)and the PKP group(n=60) according to the procedure of patients′selection.Patients in the PVP group were treated with vertebroplasty.The patients in the PKP group were treated with kyphoplasty.The operation status of the patients was analyzed statistically.The patients were followed up for 6 months,and the postoperative rehabilitation status and operation safety of the two groups were analyzed statistically.ResultsThere was no significant difference between the two groups in the amount of bleeding and the operation time(P＞0.05).The hospitalization expenses in the PKP group was higher than that in the PVP group,with significant difference(P＜0.05).The vertebral height of the two groups at 6 months after operation was significantly higher than that before operation,and the Cobb angle of the scoliosis of the two groups at 6 months after operation was less than that before operation,and the pain condition of the two groups at 6 months after operation was lower than that before operation,with significant difference(P＜0.05).The vertebral height of the PKP group at 6 months after operation was higher than that in the PVP group,with significant difference(P＜0.05).There was no significant difference in the Cobb angle and pain score between the two groups at 6 months after operation (P＞0.05).There was no significant difference in the incidence rate of complication between the two groups(P＞0.05).ConclusionThe prognosis of patients with osteoporotic thoracolumbar vertebral compression fractures treated with PKP is better,but the cost of treatment is higher.
2017 Vol. 24 (19): 71-73转80 [
Abstract
] (
147
)
HTML
(36 KB)
PDF
(0 KB) (
41
)
74
Effect study of acupuncture and exercise therapy combined with rehabilitation training as an intervention on treating knee osteoarthritis in middle-aged and elderly patients
LI Xiu-hong ；HE Yong-chang ；LUO Jian-hua ；LIANG Bi-sen
Objective To explore the effect of acupuncture and exercise therapy combined with acu-moxibustion and rehabilitation training in the treatment of knee osteoarthritis.MethodsA total of 90 patients with knee osteoarthritis treated in rehabilitation department in our hospital from February 2014 to February 2016 were selected as research objects. By random,they were evenly divided into the acupuncture and exercise therapy combined with rehabilitation training group,rehabilitation group and the medication group.In the acupuncture and exercise therapy combined with rehabilitation training group,warm needling,exercise therapy during acupunctural insertion combined with rehabilitation training were used.In the rehabilitation group,only rehabilitation training was used.In the medication group,glucosamine sulfate and Xianling Gubao for oral administration was applied.The HSS score of knee joint and the index of severity for osteoarthritis(ISOA)were selected as evaluated indicators for assessing the therapeutic effect.ResultsThe scores of HSS and ISOA after treatment in the three groups were both higher than those before treatment,with significant difference (P＜0.05).The scores of HSS and ISOA in the acupuncture and exercise therapy combined with rehabilitation training group after treatment was higher than that in the rehabilitation group and the medication group,with significant difference(P＜0.05). There was no significant difference in the scores of HSS and ISOA between the rehabilitation group and the medication group after therapy(P＞0.05).The total effective rate in the acupuncture and exercise therapy combined with rehabilitation training group was higher than that in the rehabilitation group and the medication group,with significant difference (P＜0.05).There was no significant difference in the total effective rate between the rehabilitation group and the medication group after therapy(P＞0.05).ConclusionAcupuncture and exercise therapy combined with rehabilitation training can effectively treat knee osteoarthritis,and is worthy of clinical application and promotion.
2017 Vol. 24 (19): 74-77 [
Abstract
] (
181
)
HTML
(41 KB)
PDF
(0 KB) (
48
)
78
Effect and safety comparison of screw-in self-locking nail and compression plate for internal fixation in the treatment of Pilon tibial fractures
ZHA Rui-rui；LIN Kun-shan
ObjectiveTo analyze the effect and safety of screw-in self-locking nail and compression plate for internal fixation in the treatment of Pilon tibial fractures.MethodsFrom June 2015 to July 2016,58 patients suffering from Pilon tibial fractures admitted into our hospital were selected and evenly divided into the control group and the research group according to the different surgical methods,29 cases in each group.The control group was treated with compression plate,while the research group was given screw-in self-locking nail.The clinical therapeutic effect of the two groups was compared.ResultsThe recovery excellent and good rate of the research group was 96.6%,which was higher than 72.4%of the control group,with significant difference(P＜0.05).The operation time,hospital stay,time being off bed and fracture healing time of the research group was shorter than that of the control group,and the amount of bleeding during operation of the research group was less than that of the control group,with significant difference (P＜0.05).The incidence rate of complication in the research group was 3.4%,which was lower than 24.1%of the control group,with significant difference(P＜0.05).ConclusionThe effect of screw-in self-locking nail in the treatment of Pilon tibial fracture is ideal, which not only reduces the incidence rate of postoperative complications,but also promotes the rehabilitation of the patients,it is worthy of clinical promotion and application.
2017 Vol. 24 (19): 78-80 [
Abstract
] (
198
)
HTML
(32 KB)
PDF
(0 KB) (
28
)
81
Application effect of bone cement injection treatment in osteoporotic spinal compression fractures
CHEN Shuai；YU Li-qin
ObjectiveTo explore the application effect of bone cement injection in osteoporotic spinal compression fractures.Methods80 patients with osteoporotic spinal compression fractures admitted from January to December in 2015 in our hospital were selected and randomly divided into the sparse group and the intensive group,40 cases in each group.The sparse group was injected with bone cement in the dilated vertebral vein,while the intensive group was injected bone cement in the vein concentrated area.The parameters of vertebral body,pain,daily living ability and bone cement leakage were compared between the two groups before and after treatment.ResultsThere was no significant difference in the spine height and Cobb anglebetween the two groups(P＞0.05).The VAS scores and OLBPDQ scores of the two groups after treatment were lower than those before treatment,with significant difference(P＜0.01).The VAS scores and OLBPDQ scores of the sparse group after treatment were significantly lower than those in the intensive group,with significant difference(P＜0.01).The incidence rate of total cement leakage in the sparse group was 22.5%,which was significantly lower than that in the intensive group(47.5%),with significant difference(P＜0.05).ConclusionIt is better to inject bone cement in sparse vertebral vein in osteoporotic vertebral compression fractures,and the leakage rate is lower.
2017 Vol. 24 (19): 81-83 [
Abstract
] (
171
)
HTML
(32 KB)
PDF
(0 KB) (
33
)
84
Clinical effect comparison of open reduction and internal fixation with locking plate fixation and semi shoulder arthroplasty in the treatment of proximal humeral fractures in elderly patients
ZHANG Bin-shan
ObjectiveTo explore the clinical effect of open reduction and internal fixation with locking plate fixation and semi shoulder arthroplasty in the treatment of proximal humeral fractures in elderly patients.Methods80 cases of elderly patients with proximal humeral fractures treated in our hospital from September 2014 to December 2015 were selected and divided into the internal fixation group and the replacement group according to the different operation methods,40 cases in each group.The internal fixation group was used open reduction and locking plate fixation,the replacement group was used semi shoulder arthroplasty,and the clinical therapeutic effect of the two groups were compared.ResultsThere was no statistical difference between the two groups in the operation time(P＞0.05).The amount of intraoperative bleeding in the replacement group was significantly less than that in the internal fixation group,with significant difference(P＜0.05).There was no significant difference between the two groups in the Neer score before treatment (P＞0.05).The Neer scores of the two groups after treatment was significantly higher than that before treatment,with significant difference(P＜0.05).The Neer score in the replacement group after treatment was significantly higher than that in the internal fixation group,with significant difference(P＜0.05).The excellent and good rate of the replacement group was significantly higher than that of the internal fixation group,with significant difference(P＜0.05).The incidence rate of complications in the replacement group was significantly lower than that in the internal fixation group,with significant difference(P＜0.05).The follow-up period was 3 months,the incidence rate of complications such as internal fixation loosening, dislocation,incision infection and chronic pain in the replacement group was significantly lower than that in the internalfixation group,with significant difference(P＜0.05).ConclusionOpen reduction and locking plate fixation and semi shoulder arthroplasty in the treatment of elderly patients with proximal humeral fractures have a good clinical treatment effect, and the amount of blood loss and postoperative Neer score were superior to open reduction and locking plate fixation in this study,which is wortyhy of clinical promotion and application.
2017 Vol. 24 (19): 84-87 [
Abstract
] (
146
)
HTML
(37 KB)
PDF
(0 KB) (
56
)
88
Clinical analysis of AO titanium elastic intramedullary screw in the treatment of femoral shaft fracture in children
HUANG Guang-chang；WU Sheng-peng；CHEN Yin； LIAO Wan-hua；ZHANG Jing-yu； WEN Chun-lin
ObjectiveTo explore the clinical effect of AO titanium elastic intramedullary screw in the treatment of femoral shaft fractures in children.MethodsAltogether 69 children with femoral shaft fractures who were treated in our hospital from March 2015 to March 2016 were involved as the object of this study and divided into the control group (34 cases)and the study group (35 cases)according to the random number method.The control group was treated with open reduction therap,the study group was treated with AO titanium elastic intramedullary screws.The curative effect of the two groups was compared.ResultsThe excellent and good rate of the study group was 100.00%,which was significantly higher than that of the control group(85.29%),with statistically significant difference(P＜0.05).The clinical fracture healing time and bony healing time of the study group was significantly lower than that of the control group,with statistically significant difference(P＜0.05).The incidence rate of complications of the study group was 5.71%,which was significantly lower than that of the control group(23.53%),with statistically significant difference(P＜0.05).Conclusion Application of AO titanium elastic intramedullary screw has a significant clinical effect in the treatment of femoral shaft fractures in children,and can promote the early recovery of fracture.
2017 Vol. 24 (19): 88-90 [
Abstract
] (
144
)
HTML
(30 KB)
PDF
(0 KB) (
30
)
91
The efficacy and safety of Bevacizumab combined with Paclitaxel and Carboplatin for recurrent ovarian cancer
LIU Hong-mei；LIU Shi-zhuan
ObjectiveTo explore the efficacy and safety of Bevacizumab combined with Paclitaxel and Carboplatin for recurrent ovarian cancer.MethodsFrom June 2014 to January 2016,82 recurrent ovarian cancer patients were randomly divided into treatment group(41 cases)and control group(41 cases),the control group were treated by Paclitaxel and Carboplatin,and the treatment group were treated by Bevacizumab combined with Paclitaxel and Carboplatin.The clinical efficacy(such as overall response rate,complete response rate,partial response rate),progression free survival,overall survival and the adverse reaction rate were comparatively analyzed.ResultsThe overall response rate of treatment group was 85.37%,and the overall response rate of control group was 65.85%with signifant difference.The progression free survival and overall survival of treatment group were significantly higher than those of control group（P＜0.05）.There was no statistical difference in the adverse reaction rate between two groups（P＞0.05）.ConclusionComparing with the treatment of Paclitaxel and Carboplatin,combined with Bevacizumab in the treatment of recurrent ovarian cancer have an obviously improved efficacy,significantly improved progression-free survival and overall survival in patients,there is no significant difference in safety.
2017 Vol. 24 (19): 91-93 [
Abstract
] (
194
)
HTML
(34 KB)
PDF
(0 KB) (
32
)
94
Efficacy of age and menstrual cycles on human serum HE4 and CA125 levels
LIU Yuan-ling；HUANG Xiao-fen；NIE Shi-chan；CHEN Cai-xiang；HUANG Ping
ObjectiveTo investigate the effects of age and menstrual cycle in human serum carbohydrate antigen 125 (CA125)and the human epididymis protein 4(HE4).Methods160 healthy women checked physical examination center in our hospital from January 2015 to August 2015 were divided into premenopause group(114 cases)and control group (46 cases),the premenopause group was divided into two groups,age≤35 years old(61 cases)and age＞35 years old(53 cases). Serum CA125 and HE4 levels at different stages during menstrul cycle of the groups were compared,serum CA125 and HE4 levels of the groups≤35 years old and＞35 years old at different stages during menstrul cycle were compared.ResultsThere was no statistically significant difference in serum CA125 level of the premenopause group at different stages during the menstrual cycle(P＞0.05),and there was statistically significant difference in serum HE4 level(P＜0.05), compared the luteal phase with the follicular phase,there was not statistically significant difference(P＞0.05),the follicular phase and the luteal phase were lower than those of the ovulation phase,the differences were statistically significant (P＜0.05);the serum HE4 level in the ovulation phase of the women of the group≤35 years old were higher than that of the women in the follicular phase and the luteal phase(P＜0.05),and there were no statistically significant difference in serum HE4 level at various stages during the menstrual cycle of the group＞35 years old at various stages during the menstrual cycle(P＞0.05).There were no statistically significant differences in serum CA125 level at various stages during the menstrual cycle of the group≤35 years old and the group＞35 years old at various stages during the menstrual cycle.The serum CA125 and HE4 levels in the menopause were higher than those at various stages during the menstrual cycle of the premenopause(P＜0.05),the difference was statistically significant.ConclusionThe serum HE4 level of healthy women is affected by the menstrual cycle and age,the serum CA125 level is influenced by age,the clinical definition of HE4 and CA125 in diagnosis of threshold should be considered these factors.
2017 Vol. 24 (19): 94-96转118 [
Abstract
] (
157
)
HTML
(34 KB)
PDF
(0 KB) (
35
)
97
Clinical effect of breast massage combined with postpartum rehabilitation instrument in primiparas
SHI Dan-hong； WU Li-ping ；XIAO Shu-zhu ；ZOU Dan-ling ；WANG Cun-hua
ObjectiveTo investigate the effect of breast massage combined with postpartum rehabilitation instrument in primiparas.MethodsA total of 200 cases primiparas in our hospital from July 2015 to June 2016 were randomly divided into study group and control group by means of random number table,100 cases in each group.Primiparas in control group were given breast massage,while primiparas in study group were given breast massage combined with postpartum rehabilitation instrument from the day of postpartum.Initial time of lactation,lactation volume,breast feeding condition, lactating function and hardness&tenderness breast in two groups were evaluated and compared.ResultsInitial time of lactation in study group was better than that in control group,the difference was statistically significant(P＜0.01);the rates of breast feeding and enough lactation yield in study group were 95.0%and 97.0%,and those in control group were 82.0%and 85.0%,the differences were statistically significant(P＜0.01);the scores of lactating function after 24 h and 48 h postpartum in study group were better than those in control group,the differences were statistically significant(P＜0.01);the hardness&tenderness breast condition in study group were better than those in control group,the differences were statistically significant(P＜0.01).ConclusionIt is positive to improve lactation in primiparas by using breast massage combined with postpartum rehabilitation instrument,and it has a promotion in increasing lactation yield and breast feeding rate.At the same time,it can alleviate breast hardness and tenderness.
2017 Vol. 24 (19): 97-99转131 [
Abstract
] (
149
)
HTML
(35 KB)
PDF
(0 KB) (
36
)
100
Diagnostic value of the application of MRI combined with color ultrasound or MRI alone in diagnosis of the dangerous type of placenta previa complicated with placenta accreta
LIN Hua-lan ；LAN Liu-bing ；ZHONG Jing
ObjectiveTo compare the application value of MRI combined with color ultrasound or MRI alone in diagnosis of the dangerous type of placenta previa complicated with placenta accretes.MethodsSeventy suspected cases of pernicious placenta previa complicated with placenta accrete in Meizhou People′s Hospital from October 2010 to October 2015 were selected as the research object,all of whom were examined by ultrasound and MRI in vagina.The pathological results of postpartum surgery were used as a"gold standard".The diagnostic sensitivity,specificity and accuracy of using MRI alone and MRI combined with color Doppler ultrasound in diagnosis of the dangerous type of placenta previa complicated with placenta accreta.Results58 cases were confirmed by pathological examination in the diagnosis of pernicious placenta previa complicated with placenta accrete.The coincidence rate of using MRI alone in diagnosis of placenta previa complicated with placenta accreta was 75.86% (49/70).But the coincidence rate of MRI combined with color ultrasound in diagnosis of placenta previa complicated with placenta accreta was significantly higher than that of MRI alone (χ2=10.324,P=0.001).The diagnostic sensitivity and specificity rates of using MRI alone in diagnosis of placenta previa complicated with placenta accreta were 75.86%(44/58),41.67%(5/12).But diagnostic sensitivity and specificity rates of using MRI combined with color ultrasound in diagnosis of placenta previa complicated with placenta accreta were 93.10%(54/58),83.33%(10/12)respectively,which were significantly higher than those by using MRI alone(χ2= 6.576,4.444,P=0.010,0.045).ConclusionUsing MRI combined with ultrasound and comprehensive analysis of characteristics of ultrasonography,clinical manifestations and medical history in the clinical diagnosis of placenta previa complicated with placenta accreta is helpful to reduce the misdiagnosis rate and avoid the occurrence of bleeding,uterine rupture and other serious consequences.
2017 Vol. 24 (19): 100-102 [
Abstract
] (
148
)
HTML
(32 KB)
PDF
(0 KB) (
44
)
103
Effect of laparoscopy combined with gestrinone in treatment of endometriosis and influence of patients with ovarian function
XIA Zhen；Maidiniyeti；ZHANG Lin
ObjectiveTo probe into the effect of laparoscopy combined with gestrinone in treatment of endometriosis and influence of patients with ovarian function.Methods150 cases of patients with endometriosis and who accepted treatments in our hospital from December 2014 to February 2016 were selected,and according to the different treatment methods were divided into control group and observation group,with 75 cases in each group.Patients of the control group were treated with laparoscopic surgery,while in the observation group,on the basis of treatment in the control group,they were treated with oral administration of gestrinone.Then,the clinical efficacy and the changes of patients in the two groups were compared.ResultsThere was no significant difference in operation time and blood loss during the operation between the two groups(P＞0.05).The hospitalization time in the observation group was(6.7±1.7)d,which was significantly better than that in the control group[(8.7±1.5)d](P＜0.05);the clinical effective rate in the observation group was 98.7%, which was significantly higher than that in the control group(89.3%)(P＜0.05);the recovery of ovarian function was significantly better than that of the control group(P＜0.05).ConclusionThe clinical effect of laparoscopy combined with gestrinone in treatment of endometriosis and influence of patients with ovarian function is good,which can improve the function of the ovary,and the effect is better than the patients with laparoscopic surgery.
2017 Vol. 24 (19): 103-105 [
Abstract
] (
164
)
HTML
(33 KB)
PDF
(0 KB) (
38
)
106
Related factors analysis and early diagnosis of missed abortion in elderly women
ZOU Qing-peng
ObjectiveTo explore the older pregnant women missed abortion related factors and early diagnostic methods.Methods80 cases of normal pregnant women (control group)and 80 cases of missed abortion (observation group) were selected from February 2016 to February 2017.The patients were treated with Ureaplasma Urealyticum and Chlamydia Trachomatis infection and detection of PAPP-A and progesterone were measured.The infection rate of Chlamydia Trachomatis,Uu+Ct infection rate,Ureaplasma Urealyticum infection rate,PAPP-A and P content,and serum PAPP levels at different gestational weeks(≤9 weeks,10 weeks,11 weeks,12 weeks,13 weeks,≥14 weeks)were analyzed.ResultsThe infection rate of Uu+Ct,Ureaplasma Urealyticum and Chlamydia Trachomatis in the observation group was higher than that in the control group (P＜0.05).The content of PAPP and pregnendione in the observation group was lower than that of the control group (P＜0.05).The PAPP content of pregnant women at different gestational weeks in the ob servation group was lower than that of the control group(P＜0.05).ConclusionInfection is one of the main reasons cause pregnant women missed abortion,and strengthen the determination of clinical PAPP-A and progesterone can control the incidence of miscarriage.
2017 Vol. 24 (19): 106-108 [
Abstract
] (
144
)
HTML
(33 KB)
PDF
(0 KB) (
68
)
109
Evaluation of the feasibility and safety of laparoscopic surgery for ovarian cysts in pregnancy and its impact on pregnancy outcome
MO Jin-feng
ObjectiveTo study and discuss the feasibility and safety of laparoscopic surgery in the treatment of pregnancy complicated with ovarian cyst and its influence on the pregnancy outcome.MethodsFrom January 2010 to May 2016,80 cases of pregnancy patients with ovarian cyst were selected as the research object,the patients were randomly divided into two groups by taking computer single blind randomization method,the control group was given the conventional ovarian cystectomy treatment,the observation group was given laparoscopic ovarian cyst resection treatment.The operation condition and outcome were compared between two groups.ResultsOperation situation:the operation time in the observation group was significantly shorter than the control group (P＜0.05),the amount of bleeding during operation was significantly less than the control group(P＜0.05);postoperative ambulation time and exhaust time for the first time in the observation group were significantly earlier than the control group(P＜0.05);the postoperative hospital stay in the observation group was significantly shorter than the control group(P＜0.05);pain score in the observation group after surgery was significantly lower than the control group(P＜0.05);the rate of postoperative complications in the observation group was significantly lower than the control group(P＜0.05);sex hormone,luteinizing hormone,follicle stimulating hormone and estradiol glycol in the observation group after surgery were significantly increased and higher than the control group after surgery(P＜0.05).Pregnancy outcomes:the cesarean section rate in the observation group was significantly lower than that of the control group(P＜0.05),while the rate of premature delivery,the rate of miscarriage and the rate of neonatal asphyxia were compared between the observation group and the control group,there were no significant differences(P＞0.05).Conclusion For patients with ovarian cyst of pregnancy by laparoscopic ovarian cyst resection treatment is feasible,not only has less surgical trauma,faster postoperative recovery,less complications and other advantages,can effectively ensure the safety of pregnancy outcomes,avoid adverse pregnancy outcomes.
2017 Vol. 24 (19): 109-111转138 [
Abstract
] (
152
)
HTML
(39 KB)
PDF
(0 KB) (
65
)
112
Influence of strengthening gestational standardized management on pregnancy outcome in advanced maternal age
PAN Yan-jun
ObjectiveTo investigate the influence of strengthening gestational standardized management on pregnancy outcome in advanced maternal age (AMA).Methods190 AMA patients
received：
antenatal examination in our hospital from February 2014 to August 2016 were selected as observation group,and they were given gestational standardized management;and another 190 AMA outpatients without gestational standardized management in our hospital were selected as control group.The accompany diseases during pregnancy,complications and pregnancy outcomes of two groups were compared.ResultsThe incidence of gestational diabetes mellitus,gestational hypertension,anemia during pregnancy, postpartum hemorrhage,premature rupture of membrane,puerperal infection of observation group was lower than that of the control group(P＜0.05);there was no statistical difference in the incidence of placenta previa between two groups(P＞0.05);the incidence of low birth weight infant,premature birth,macrosomia,birth defect,neonatal asphyxia,fetal malformation,perinatal mortality of observation group significantly decreased compared with control group(P＜0.05).Conclusion Strengthening gestational standardized management for AMA can effectively decrease adverse pregnancy outcomes,which is worthy of clinical promotion.
2017 Vol. 24 (19): 112-114 [
Abstract
] (
133
)
HTML
(30 KB)
PDF
(0 KB) (
62
)
115
Clinical application of hysteroscopy in patients with endometrial thickening lesions
YIN Xiao-jun ；LI Ran
ObjectiveTo investigate the clinical application significance of hysteroscopy in patients with endometrial thickening lesions.Methods120 patients from May 2015 to December 2016 in our hospital were selected,all the patients
received：
transvaginal ultrasound examinations because of abnormal vaginal bleeding and the ultrasound results showed endometrial thickening.60 cases who were given the diagnostic curettage were selected as the diagnostic curettage group,60 cases received hysteroscopy in in-patient department were selected as the hysteroscopy group.The differences of diagnostic results of the two groups were compared and analyzed.ResultsThe detection rate of endometrial polyp, submucosal myoma of uterus and uterine adhesions in hysteroscopy group was higher than that in the diagnostic curettage group respectively,the difference was statistically significant(P＜0.05);the sensitivity,specificity,positive predictive value and negative predictive value of the endometrial polyp,submucosal myoma of uterus and endometrial hyperplasia in the hysteroscopy group was statistically higher than that in the diagnostic curettage group.ConclusionHysteroscopy has the advantage of direct sight of intrauterine lesions,drawing target materials and higher diagnosis accuracy,it is worth for the diagnosis of endometrial thickness.
2017 Vol. 24 (19): 115-118 [
Abstract
] (
127
)
HTML
(36 KB)
PDF
(0 KB) (
37
)
119
Effect of application of different ovarian stimulation protocols on women with decreased ovarian reserve functions
WANG Bin ；LIANG Jian-di；PENG Yu-hong； CHEN Hui-nan； LIU Zhi-gang ；MO Yu-qin
ObjectiveTo study the effect of application of different ovarian stimulation protocols in women with decreased ovarian reserve functions.MethodsAltogether 56 cases of female patients with decreased ovarian reserve functions who were treated in our hospital from June 2015 to May 2016 were selected as the study object and divided into two groups according to the ovarian stimulation protocols;28 patients who underwent ovarian stimulation in the late luteal phase were involved as observation group;while,another 28 patients who underwent short-acting long protocol stimulation were involved as control group.The endometrial thickness,E2level at the day of HCG administration,number of oocytes and the number of high-quality embryos were compared between the two groups.ResultsThe Diphereline usage days, E2level at the day of HCG administration,the number of oocytes and the number of high-quality embryos of observation group were(10.15±0.37)d,(1734.12±165.61)pg/ml,(8.30±1.17)eggs and(4.60±0.82)embryos,significantly better than those of control group[(25.45±1.65)d,(1308.87±143.30)pg/ml,(7.20±0.76)eggs and(2.60±0.50)embryos](P＜0.05).There was no statistically significant difference in the LH and P level at the day of HCG administration,endometrial thickness and total Gn between two groups(P＞0.05).ConclusionApplication ovarian stimulation at the late stage of luteal phase can improve the number of obtained oocytes,available embryos and high-quality embryos,which can shorten the Diphereline usage days and reduces the cost of treatment.
2017 Vol. 24 (19): 119-121 [
Abstract
] (
130
)
HTML
(32 KB)
PDF
(0 KB) (
38
)
122
Efficacy of angelica chicken decoction diet conditioning combined with breast massage on milk accumulation in community
ZHANG Dan ；REN Su-ying；ZHOU Guo-hua
ObjectiveTo observe the efficacy efficacy of angelica chicken decoction diet conditioning combined with breast massage on milk accumulation in community.MethodsA total of 400 postpartum labored in our hospital from June 2016 to May 2017 and with milk accumulation in community were selected and divided into the observation group and the control group according to different intervening method,with 200 cases in each group.The fade time of breast tenderness,breast hardness,breast pain and the breastfeeding rate were compared between two groups.ResultsThe fade time of breast tenderness in the observation group[(2.0±0.6)d]was shorter than that in the control group[(4.2±1.1)d]. 14 days after delivery,the breast hardness and the score of breast pain in the observation group[(2.4±1.1)points]were lower than those in the control group[(3.7±0.8)points],the breastfeeding rate(98.0%)was higher than that in the control group (90.0%),and the differences were statistically significant(P＜0.05).ConclusionMaternal postpartum diet conditioning with breast massage can effectively reduce maternal milk accumulation.
2017 Vol. 24 (19): 122-124 [
Abstract
] (
155
)
HTML
(31 KB)
PDF
(0 KB) (
38
)
125
Efficacy of pregnancy health care on pregnancy and labor complications and pregnancy outcomes in elderly puerpera
LI Qing-hua；LIANG Yin-hua；LI Cui-li
ObjectiveTo explore the efficacy of pregnancy health care on pregnancy and labor complications and pregnancy outcomes in elderly puerpera.MethodsA total of 780 elderly puerpera who were given antenatal care in our hospital from January 2016 to January 2017 were selected,and their clinical data were retrospectively analyzed.390 pregnant women with the number of antenatal care of more than 7 times(including 7 times)were assigned to the observation group,and 390 pregnant women with the number of antenatal care of less than 7 times were assigned to the control group.The neonatal complications and gestational outcome were compared and analyzed between the two groups during pregnancy and labor.ResultsThe incidence rates of intrahepatic cholestasis of pregnancy(ICP),pregnancy-induced hypertension and diabetes mellitus,premature rupture of membranes,preeclampsia,advanced abortion rate,postpartum hemorrhage and perinatal infection in the observation group were lower than those in the control group;the incidence rates of neonatal asphyxia,hypoglycemia,macrosomia,erythrocytosis and hyperbilirubinemia were lower than those in the control group，and the differences were statistically significant(P＜0.05).ConclusionThe application of standardized pregnancy health care in elderly puerpera during pregnancy and labor can significantly reduce the incidence rate of complications,and effectively improve the prognosis of delivery,which is suitable for promotion.
2017 Vol. 24 (19): 125-127 [
Abstract
] (
163
)
HTML
(31 KB)
PDF
(0 KB) (
41
)
128
Analysis on the pregnancy outcomes of fetal isolated enlarged cisterna magna
LIN Yu-jiao； LIU Juan； ZHONG Jin
ObjectiveTo explore the pregnancy outcomes in fetuses with isolated enlarged cisterna magna(IECM).Methods48 fetuses with IECM(the study group)and 60 normal fetuses(the control group)at our hospital from January 2011 to June 2015.All infants were assessed the gross motor,fine motor,adapting abilities,language and social interaction by the Gesell Developmental Schedules,and also evaluated the development quotient.ResultsThe Gesell developmental value of gross motor and adapting abilities and the development quotient of infants in the study group were lower than those in the control group,and the differences were statistically significant(P＜0.05).There were no significant differences between the Gesell developmental value of fine motor,language and social interaction in two groups(P＞0.05).In the study group, the Gesell developmental value of gross motor of male infants was higher than that of the female infants,and the difference was statistically significant(P＜0.05).There were no significant differences between the other four Gesell developmental values (fine motor,adapting abilitieslanguage and social interaction)and development quotient in two groups(P＞0.05).ConclusionThe developmental abilities of infants with prenatal IECM are similar to those of normal fetuses,except for some subtle deficits in adapting and gross motor abilities.
2017 Vol. 24 (19): 128-131 [
Abstract
] (
129
)
HTML
(39 KB)
PDF
(0 KB) (
31
)
132
Correlation analysis of influencing factors of coronary artery diameter in children aged 3 years in Pingxiang area
XIAO Feng ；ZHANG Yi；LI Hua-ping
ObjectiveTo measure the normal value of coronary artery in children under 3 years old in Pingxiang,and to analyze the results and explore the influencing factors.Methods300 cases of children under the age of 3 were selected from October 2014 to October 2016 in five maternal and child health hospital were divided into three groups according to age,0-1 years old group,＞1-2 years old group and＞2-3 years old group.Measured the height and weight of all children, and calculate the surface area.The left coronary artery(LCA),right coronary artery(RCA)and total dry aortic root diameter(AO)was measured in children total dry by ultrasound.The statistical analysis software SPSS 18.0 was used to analyzedthe calculation of LCA/AO and RCA/AO value in normal healthy children with coronary artery diameter within 3 years old statistics in Pingxiang area.ResultsThe children under 3 years of age in Pingxiang the coronary artery diameter measurement increases with age,there was significant difference in different age groups(P＜0.05);there was no significant difference between the 0-1 years old group with＞1-2 years old group and＞1-2 years old group with＞2-3 years old)group of LCA/AO and RCA/AO(P＞0.05);Logistic linear regression analysis showed that LCA were related to theage, height,weight and body surface area(r=0.904,0.912,0.916,0.942,P＜0.05),RCA were related to the age,height,weight and body surface area(r=0.861,0.922,0.928,0.905,P＜0.05).ConclusionIn Pingxiang,3 years old children of coronary artery diameter is relate with age,height,weight,body surface area.The coronary artery diameter and the diameter ratio of AO changed a little,it can bea ideal index for coronary artery dilatation.To further expand the scope of domestic children′s coronary artery normal value is necessary.
2017 Vol. 24 (19): 132-134 [
Abstract
] (
124
)
HTML
(32 KB)
PDF
(0 KB) (
46
)
135
Etiological characteristics analysis of community-acquired pneumonia in children from 2013 to 2016 in Shanwei City
CHEN Qiu-yang；ZHUANG Cheng-lin； ZHOU Si
ObjectiveTo analyze the etiological characteristics of community-acquired pneumonia(CAP)in children in Shanwei city in recent years.MethodsA total of 1254 children with CAP from January 2013 to December 2016 were collected from outpatient clinics.They were divided into preschool group,infant group,and neonatal group based on different ages.The detection of common bacteria,virus,mycoplasma and mixed infection was compared as well as the distributions of these bacteria,virus,and mycoplasma among four seasons.ResultsThe positivity rate of bacterial detection was 55.50%,and 696 strains were detected.Among these detected strains,Hemophilus parainfluenzae took up for 41.67%,followed by Streptococcus pneumoniae accounting for 25.00%,which were higher than the other bacteria.The viral positivity rate was 35.01%,of which 68.34%for RSV and 17.77%for ADV,higher than other viruses in significant differences.The proportion of detections of virus and mycoplasma in the neonatal group was the highest.There were great differences in Staphylococcus aureus,Escherichia coli,RSV,and PIV3 among three groups.54.79%children suffering from bacterial and viral infection,which was the highest in the neonatal group.The positivity rate of mycoplasma was 33.25%. The total detection rates of bacteria in spring and winter were the highest.The Hemophilus influenza was detected in spring in highest detection rate.In winter,the total detection rate of virus was highest,of which RSV,PIV3,and ADV were frequently detected in winter,spring,and summer respectively(all P＜0.05).The possibility of mycoplasma detection is higher inspringcomparedwithother seasons(P＜0.05).ConclusionMycoplasma infection in CAP children in Shanwei city is common in recent years.Haemophilus paragallinus is the primary bacterial pathogen,RSV as the primary viral pathogen,and the main mixed infection pathogen is virus combining with bacterium.Spring and winter are the active periods for bacteria,viruses,mycoplasmas in higher detection rates.
2017 Vol. 24 (19): 135-138 [
Abstract
] (
137
)
HTML
(37 KB)
PDF
(0 KB) (
37
)
139
Analysis of ultrasonographic features and clinical characteristics in children with temporary small intussusception
LIN Shu-lian ；JIANG Shuang-lan ；BU Qiu-qiang ；YU Feng ；XIAN Yun-kai
ObjectiveTo study the ultrasonographic and clinical features of temporary small intussusception in children.MethodsRetrospective analysis of 440 children of abdominal discomfort in our hospital from January 2015 to November 2016 was performed.By ultrasonography,88 children patients were diagnosed as temporary small intussusception.The clinical manifestations,characteristics of ultrasonography and therapeutic methods were analyzed and summarized.ResultsWith regard to correlation of the length and diameter of intussusception and the age,the older the children patient was,the larger the length and diameter of intussusception were.ConclusionTemporary small intussusception in children is caused by transient intussusception of the small intestine,which is commonly seen in children with intussusception. Characterized by spontaneous reduction,non-special treatment,and non-surgery,repetitive ultrasonography for these children patients is necessary in clinic.Conservative therapeutic regimen is adopted after a comprehensive understanding of the small intussusception.
2017 Vol. 24 (19): 139-141 [
Abstract
] (
136
)
HTML
(30 KB)
PDF
(0 KB) (
42
)
142
Clinical value analysis of speckle tracking imaging in evaluation of changes of cardiac function in pregnancy-induced hypertension patients in different pregnancy phase
QIU Shun-ping ；WANG Ya； WU Cheng-bai
Objective To investigate the clinical value of speckle tracking imaging(STI)in evaluation of changes of cardiac function in pregnancy-induced hypertension(PIH)patients in different pregnancy phase.Methods62 PIH patients in our hospital from July 2014 to June 2016 were selected as the observation group,and 62 pregnant women with pregnancy examination were selected as the control group at the same time.The imaging of left ventricular cardiac base (MV)level,apex(AP)level of two groups were collected,and which was analyzed by STI.The rotation angle,twist angle of the two groups in different pregnancy phase were compared.ResultsThe peak value of twist angle(Ptw),peak apical rotation angle(Prot-AP)of the observation group in early,mid-pregnancy phase were larger than those of the control group,with significant difference(P＜0.05).Compared with early pregnancy phase,the Ptw,Prot-AP value of the observation group and the control group in mid-pregnancy increased,and the Prot-AP value in late phase decreased,with significant difference(P＜0.05).Compared with mid-pregnancy phase,the Ptw value of late pregnancy phase in the two groups increased,with sig nificant difference(P＜0.05).There was no significant differencein the peak rotation-MV(Prot-MV),peak time-MV(Pti-MV) levelsintheeachphase between the two groups(P＞0.05).The percent of peak time-MV(Perc-Pti-MV)in early pregnancy,midpregnancy,late pregnancy,Perc-Pti-MV,Pti-AP in late pregnancy phase of the observation group were larger than those of the control group,with significant difference(P＜0.05).ConclusionThe early application of STI in PIH patients can effectively observe left ventricular torsion and rotation motion,facilitate early evaluation of cardiac function of PIH patients.
2017 Vol. 24 (19): 142-144 [
Abstract
] (
145
)
HTML
(33 KB)
PDF
(0 KB) (
44
)
145
Clinical effect of Thymosin Injection combined with Azithromycin treating the secondary pulmonary infection of chronic obstructive pulmonary disease in the elderly
XIA Kou-ping；ZHOU Ying-yong
ObjectiveTo evaluate the clinical effect of Thymopeptide Enteric Injection combined with Azithromycin treating the secondary pulmonary infection of chronic obstructive pulmonary disease in the elderly.MethodsFrom June 2016 to February 2017,data of 80 patients with the secondary pulmonary infection of chronic obstructive pulmonary disease were selected and counted and analyzed.All the patients were divided into the Azithromycin group and combined treatment group by the random number table method,and there were 40 cases in each group.Azithromycin group was given Azithromycin treatment,and the combined treatment group was treated with Thymopeptide Enteric Injection on the basis of Azithromycin group.The treatment effect,blood gas analysis index improvement,pulmonary function improvement,adverse drug reaction rate and cure time were compared between the two groups.ResultsTreatment effect, blood gas analysis indicators improvement,pulmonary function improvement were better than Azithromycin group(P＜0.05). The incidence rate of adverse drug reactions in combined treatment group was lower than that of Azithromycin group (P＜0.05).Cure time of combined therapy group was shorter than that of the Azithromycin group (P＜0.05).Conclusion Treatment effect of Thymopeptide Enteric Injection combined with Azithromycin in treating the secondary pulmonary infection of chronic obstructive pulmonary disease in the elderly is prominent,and the improvement of blood gas analysis and lung function indicators are better,and the cure time is short,adverse drug is few.It is worthy of clinical reference.
2017 Vol. 24 (19): 145-147 [
Abstract
] (
144
)
HTML
(36 KB)
PDF
(0 KB) (
38
)
148
The clinical study of low dosage of Losartan combined with the Prescription of Strengthening Kidney and Reducing Acid treating the early primary gouty nephropathy
LIU Han-wei；TANG Ji-wen；ZOU Li-e；LING Jia-sheng
ObjectiveTo investigate the clinical effect of low dosage of Losartan combined with the Prescription of Strengthening Kidney and Reducing Acid treating the early uric acid nephropathy.MethodsA total of 100 patients with early uric acid nephropathy admitted into our hospital from September 2014 to September 2016 were selected and divided into two groups:control group and observation group with 50 cases in each group according to the principle of randomized controlled classification.Based on the basis of the same treatment,the patients of the control group was treated with Allopurinol and the patients of the observation group was treated with low dosage of Losartan combined with the prescription of Strengthening Kidney and Reducing Acid.After 3 months of continuous treatment,the clinical symptoms improvement,the improvement of clinical indexes and the clinical efficacy between the two groups were compared.ResultsAfter treatmrent,the improvement of clinical symptoms,renal function index and 24 h urine protein quantitative were significantly better than those of the control group after treatment and the difference was statistically significant(P＜0.05).After treatment,the total effective rate of the observation group was significantly higher than that of the control group and the differencewasstatisticallysignificant(P＜0.05).ConclusionLowdosageofLosartancombinedwiththe PrescriptionofStrengtheningKidney and Reducing Acid treating the early uric acid nephropathy can clinical symptoms, renal function,uric acid,24 h urinary protein and other short-effect index,and it can protect renal function,improve the total efficiency rate of clinical treatment,and it is a feasible treatment method.It is worthy of further clinical application and promotion in clinic.
2017 Vol. 24 (19): 148-150 [
Abstract
] (
122
)
HTML
(35 KB)
PDF
(0 KB) (
35
)
151
Efficacy and safety study of Infliximab combined with Methotrexate in the treatment of active rheumatoid arthritis
XIA Zhi-gao；LIU Cai-yang
ObjectiveTo investigate the clinical therapeutic effect and safety of Infliximab combined with Methotrexate treating active rheumatoid arthritis(RA).Methods70 patients with active RA admitted into some hospital from Septem ber 2015 to September 2016 were selected and they were randomly divided into study group and control group,and there were 35 cases in each group.The patients of control group were given Methotrexate for treatment,and patients of research group were given Infliximab combined with Methotrexate.The clinical effect,the improvement of clinical symptoms,the change of the related clinical indexes and adverse reaction were compared in two groups.ResultsAfter treatment,the changes of clinical treatment effect,symptom improvement and related indicator level were significantly better than those of the control group and the differences were statistically significant(P＜0.05).ConclusionThe combination of the two medicines has the characteristics of good clinical effect,fast action,speedy symptom control rate and strong antiinflammatory action and so on.It is safe and efficient so that it can be greatly promoted in clinic.
2017 Vol. 24 (19): 151-153 [
Abstract
] (
161
)
HTML
(35 KB)
PDF
(0 KB) (
39
)
154
Influence of system intervention on cognition and behavior of high risk patients with stroke in Nanchang City
ZHOU Feng ；CHEN Xiao-hong ；LIU Xing-yuan； YU Shu-qin； LUO Li-hua ；ZENG Mei-hong ；DENG You-qing
ObjectiveTo explore the influence of system intervention on the cognition and behavior of high risk patients in stroke in Nanchang City.Methods172 people were selected from 1359 faculty members aged over 40 years old(including 40 years old)from Nanchang City Education System from January 2015 to December 2015 in our hospital according to the National Health Commission"Risk Assessment Table for High Risk Population of Stroke"high risk of stroke, and systematic intervention was carried out for these high-risk populations.The improvement of awareness rate of stroke prevention and treatment,the improvement of bad habits before and after intervention were compared.ResultsThe awareness rate of stroke prevention and control knowledge among 172 high-risk stroke patients was 87.8%(151/172),which was significantly higher than that of 25.6%(44/172)before intervention,the difference was statistically significant(χ2=19.660, P＜0.05).After the intervention,the risk of living habits of 172 high-risk workers was significantly reduced,the moderate exercise rate was significantly increased,the difference was statistically significant(P＜0.05).ConclusionSystem intervention can effectively improve the awareness rate of disease prevention and control in high risk population of stroke and correct the bad living habits of the target population,and it is worthy tof promotion and application.
2017 Vol. 24 (19): 154-156 [
Abstract
] (
162
)
HTML
(32 KB)
PDF
(0 KB) (
30
)
157
Investigation and analysis of training on nursing staff providing for the aged developed in fresh graduate with nursing specialty and employment state
MA Xin-ling； HUANG Fang-yan；YOU Ai；LYU Hui
Objective To understand the training effect of nursing staff providing for the aged developed in fresh graduate with nursing specialty and employment state to provide a reference for the further training and employment guidance.MethodsA total of 92 fresh graduate with nursing specialty attended to the training on nursing staff providing for the aged in our school and obtained the quality of nursing staff from May 2013 to May 2015 were selected as objects. Questionnaires and telephone follow-up were used to collect the training related information and employment.The influence factors were analyzed integrally.ResultsMost of graduates(97.8%)attended to the training on nursing staff providing for the aged in their own will.However,their expectation of employ turned to be different from their real employment. 47 cases(51.1%)of them worked in the third-class hospital and others worked in medical institutions under grade three. No one worked in a professional pension institution.The factors influencing students′job hunting rank as follows:salary level,career development prospects,work intensity,social status,professional counterparts,etc.ConclusionIt is popular to carry out the training on nursing staff providing for the aged in fresh graduate with nursing specialty,however,graduates who have obtained the qualifications of the nursing staff have not selected the employment of the professional pension institutions as the first choice.Thus,trainers should pay attention to the selecting the training personnel and training methods,and the government and employers should formulate corresponding measures to guide employment.
2017 Vol. 24 (19): 157-159转169 [
Abstract
] (
109
)
HTML
(36 KB)
PDF
(0 KB) (
33
)
160
Comparative analysis of disease control in patients with severe mental disorder in different educational level
KE Qiang；ZHANG Wen-feng；WENG Hua；XU Qiong
ObjectiveTo compare the disease control in patients with severe mental disorder in different educational levels.MethodsFrom September to December in 2016,patients with severe mental disorders who were in follow-up service information registration in the National Severe Mental Disorder Management System were selected as objects.According to different educational levels including high school,technicalschool,and technical secondary school and superior ones,junior high school,and primary school and inferior ones,they were divided into high school group,junior high school group,and primary group,and there were 300 patients in each group.The disease control among the three groups was compared.ResultsThe awareness of the patients in the junior high school group was significantly higher than that in the primary school group,but lower than that in the high school group with statistical difference(P＜0.05).The control rate of disease in the junior high school group was 50.0%,and it was significantly higher than that of the primary school group (36.7%);the control rate of disease in the high school group was 66.7%,and it was significantly higher than that of the junior high school group(50.0%)and primary school group(36.7%)with statistical difference(P＜0.05).The incidence of behavior disorders in the junior high school was lower than that in the primary school group,and the incidence of behavior disorders in the high school group was the lowest with statistical difference(P＜0.05).ConclusionThe disease control in patients with severe mental disorders is different based on different educational level.Patients with higher educational levels,the disease control is better,viceversa.The corresponding health education is necessary targeting on severe mental disorders patients in different educational level in order to improve the disease control rate.
2017 Vol. 24 (19): 160-162 [
Abstract
] (
149
)
HTML
(33 KB)
PDF
(0 KB) (
36
)
163
Discussion on the relationship between work empowerment of and work stress source in nurses
DING Xue-mei；YU Hui-xia；TAN Li-mei
ObjectiveTo explore the relationship between work empowerment and stress sources of clinical nurses,so as to provide bases for clinical improvement of nursing quality and management effectiveness.Methods500 clinically registered nurses who directly provided nursing services for the patients for over one year in the departments of emergency, internal medicine,surgery,gynecology and obstetrics,pediatrics and other departments in some hospitals in Baoan District and community health service centers from January 2011 to December 2014 were randomly selected,and the questionnaire survey was carried out in the nurses.ResultsThe education background,title,working years and monthly income had significant effect on the working empowerment of the nurses(P＜0.05).Age,marital status,departments and other factors did not have significant effect on the working empowerment of nurses(P＞0.05).All the scores of working empowerment structures were above the moderate level with opportunity score was the highest[(3.23±0.98)points]and resources score was the lowest[(2.67±0.78)points].The overall pressure level score[(2.62±1.21)points]was higher according to the stress sources of working empowerment of nurses.Various dimensions of working empowerment of nurses were correlated with a variety of reasons.They were negatively correlated with work shift,heavy workload,tense nurse-patient relationship,excessive useless paper work,worries about errors in the stress sourses,and they were positively correlated with duties of nursing care,poor benefits for the patients and few opportunities of further study.ConclusionThe construction of a working environment for the working empowerment of nurses is beneficial to relieving the pressure from the work.
2017 Vol. 24 (19): 163-165 [
Abstract
] (
139
)
HTML
(31 KB)
PDF
(0 KB) (
40
)
166
Analysis on the adverse reactions and safety medication of Misoprostol in our hospital in 2016
ZHONG Jie-xia；LI Jun；YU Bi-xia；HUANG Xiang-zhen
ObjectiveTo compare the adverse reactions of Misoprostol in our hospital in 2016 and the past four years (2012-2015),and to understand the current status of adverse reactions of Misoprostol in our hospital,so as to make suggestions for the future clinical safety medication,and to promote the reasonable application of Misoprostol.MethodsThe information of adverse reactions of Misoprostol in our hospital in 2016 and the past four years(2012-2015)was collected, retrospectively analyzed and compared in table.ResultsIn the past four years(2012-2015),only 1 case of Misoprostol induced adverse reactions was reported in 2015,and the type of reaction was moderate.5 cases were reported in 2016,and the number of cases showed a sharp upward trend,and the adverse reactions were all new moderate adverse reactions.The reasons for the increase in the number of cases might be related to the continuous improvement of the monitoring work of adverse reactions,the increasingly wide use of drugs,the clinical route of administration,and patients′medication.ConclusionDue to the increase in the number of adverse reactions and the emergence of new types of adverse reactions,it is necessary to strengthen the medication safety works of Misoprostol.
2017 Vol. 24 (19): 166-169 [
Abstract
] (
158
)
HTML
(38 KB)
PDF
(0 KB) (
29
)
170
Study on the influence of psychological resilience for bad psychological problems of the old age patients with cardiovascular disease.
NIU Jun-zhi
ObjectiveTo explore the influence of psychological resilience on bad psychological problems of the old age patients with cardiovascular disease.Methods200 old age patients with cardiovascular disease who were treated in the department of cardiology of our hospital from October to December 2016 were selected.The level of psychological resilience of them was evaluated using CD-RISC,and their bad psychological problems was evaluated using SCL-90,the result was compared with the national norm.ResultsThe total score of CD-RISC was(65.49±11.41)points,Totality showed the medium level,the total score of SCL-90 was(148.79±29.52)points,it was higher than[(129.96±38.76)points]of the national norm(t=6.60,P＜0.01).Correlation analysis showed that the score values of SCL-90 showed a negative correlation with the score values of CD-RISC(r=-0.458,P＜0.01).Regression analysis showed psychological resilience had a quite strong predictive effect for psychological problems(β=0.634,P＜0.01),it could explain 29.7%of amount of variation of psychological symptoms.Conclusion Psychological resilience is a predictive factor of psychological problems,and improving positive psychological resilience can help preserve body and mind health of the old age patients with cardiovascular disease.
2017 Vol. 24 (19): 170-173 [
Abstract
] (
145
)
HTML
(41 KB)
PDF
(0 KB) (
43
)
174
Influence of health self-management ability on life quality of elderly patients with chronic disease in country
CHENG Xiang-dong
ObjectiveTo explore the influence of health self-management ability on life quality of elderly patients with chronic disease in country.MethodsFrom October to December 2016,1000 elderly patients with chronic disease in country and 1000 healthy elderly people were investigated using AHSMSRS and GQOLI-74.ResultsThe total score of AHSMSRS of the elderly patients with chronic disease in country was(117.24±10.42)points,and it was lower than that of the healthy elderly people[(130.58±11.24)points](t=48.16，P＜0.01).The total score of GQOLI-74 of the elderly patients with chronic disease in country was(169.70±12.25)points,and it was lower than that of the healthy elderly people[(195.03± 15.62)points](t=40.35,P＜0.01).Correlation analysis showed that the score value of GQOLI-74 scale had a positive correlation with the score value of AHSMSRS scale(r=0.458,P＜0.01).Multivariate regression analysis showed that health self-management ability had a quite strong predictive effect for life quality(β=0.0717,P＜0.01).ConclusionHealth self-management skill of the old age patients with chronic in country ware more lower,their life quality are not high,aand health self-management ability is the predictive factor influencing the life quality.
2017 Vol. 24 (19): 174-177 [
Abstract
] (
140
)
HTML
(40 KB)
PDF
(0 KB) (
29
)
178
Family doctors interfere with the quality of life in patients with gouty arthritis
YANG En-yi
ObjectiveTo explore the effect of family intervention on the quality of life of patients with gouty arthritis.MethodsIn Guangzhou City,Liwan District Hualin street community health service center of patients with gouty arthritis in 200 cases,the object of study selected time for the January 2016 to December,were grouped according to their different ways of intervention,the contrat group and experimental group,with 100 cases in each group.The control group
received：
routine nursing intervention,the experimental group received the intervention of the family doctor,compared two groups of gouty arthritis patients of intervention effectiveness and quality of life.ResultsThe two groups of patients with gouty arthritis after intervention than before intervention to improve the quality of life,improve the quality of life in the experimental group than control group(P＜0.05);the total efficiency after the intervention ofthe experimental group(92.00%)was significantly higher than that of the control group(64.00%),P＜0.05.ConclusionIntervention by family physicians of patients with gouty arthritis，can promote the clinical symptoms，improve the environment，social，psychological,physiological and related quality of life,so that patients can maintain a more positive state of treatment,improve the prognosis.
2017 Vol. 24 (19): 178-180 [
Abstract
] (
135
)
HTML
(31 KB)
PDF
(0 KB) (
52
)
181
Application observation of comprehensive nursing intervention in patients with cerebral thrombosis
PENG Ying-ying ；GAN Wen-jie； FENG Li-mian ；CHAO Shan-shan
ObjectiveTo investigate the efficacy of comprehensive nursing intervention in patients with cerebral thrombosis.Methods240 patients with cerebral thrombosis treated in Department of Neurologyin our hospital from February 2015 to February 2016 were selected and divided into the control group and the observation group according to the different nursing measures,with 120 cases in each group.The control group was given basic nursing measures,while the observation group was given comprehensive nursing intervention.The average delayed thrombolytic time,average hospitalization time,pre-and post-nursing neurological deficit score,Barthel index score as well as of the recurrence rate and patients′satisfaction degree were compared between two groups.ResultsThe average delayed thrombolytic time and average hospitalization time in the observation group were shorter than that in the control group,and the differences were statistically significant(P＜0.05).Before nursing,there were no significant differences between the scores of neurological deficit and Barthel index in two groups(P＞0.05);after nursing,the scores of neurological deficit in two groups were all decreased,the scores of Barthel index in two groups were all increased,and compared with those before nursing,the differences were statistically significant(P＜0.05).And the score of neurological deficit in the observation group was lower than that in the control group,the score of Barthel index was higher than that in the control group,and the differences were statistically significant(P＜0.05).The recurrence rate in in the observation group was lower than that in the control group,the patients′satisfaction degree was higher than that in the control group,and the differences were statistically significant(P＜0.05).ConclusionApplication of comprehensive nursing intervention in patients with cerebral thrombosiscan improve the treatment efficiency,neurological functions,life ability and patients′satisfaction,and reduce the recurrence rate,which is worthy of clinical application.
2017 Vol. 24 (19): 181-183转186 [
Abstract
] (
147
)
HTML
(35 KB)
PDF
(0 KB) (
41
)
184
Exploration of nursing strategies on patients with permanent artificial pacemaker
LUO Hui-hong
ObjectiveTo explore the nursing strategies on patients with permanent artificial pacemaker.Methods46 patients who were implanted with permanent artificial pacemakers from April 2015 to February 2017 were selected in the study.According to the random number table,they were evenly divided into the control group ang the observation group, with 23 cases in each group.The control group was given conventional nursing strategy,while the observation group was given detailed nursing.The before and after nursing,nursing satisfaction,the incidence of complications were compared between two groups.ResultsBefore nursing,there were no significant differences among the scores of indexes in emotional state in two groups(P＞0.05);after nursing,the scores of indexes in two groups were all decreased,and compared with those before nursing,the differences were statistically significant(P＜0.05),and those in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).The nursing satisfaction in the observation group was higher than that in the control group,the incidence of complications was lower than that in the control group,and the differences were statistically significant(P＜0.05).Conclusion The detailed nursing strategy on permanent artificial pacemaker can obtain a definite effect by alleviating bad emotions,reducing the occurrence of complications after implanatation,and improving nursing satisfaction,which is worthy of extensive application.
2017 Vol. 24 (19): 184-186 [
Abstract
] (
122
)
HTML
(31 KB)
PDF
(0 KB) (
72
)
187
Efficacy evaluation of humanized nursing applied to maternal natural childbirth
CHEN Xiu-tian ；CHEN Ya-lan ；LIN Wei；CHEN Gui-mei
ObjectiveTo explore the efficacy evaluation of humanized nursing applied to maternal natural childbirth.Methods80 puerperaes in our hospital from January 2015 to January 2017 were selected as the research objects,according to random number table,they were randomly divided into the observation group and the control group,with 40 cases in each group.The observation group was given humanized nursing,and the control group was given traditional nursing.The delivery mode,the amount of postpartum bleeding,stages of labor,the incidence of fetal distress,the Apgar score of newborns and nursing satisfaction were compared between two groups.ResultsThe natural childbirth rate (72.5%)and nursing satisfaction(90.0%)in the observation group were higher than those in the control group(52.5%, 72.5%),the incidence of caesarean section(12.5%)and fetal distress(15.0%)were lower than those in the control group (32.5%,30.0%),the amount of postpartum bleeding[(276.4±58.1)ml]was lower than that in the control group[(355.6± 60.2)ml],the stages of labor[(8.1±2.4)h]was shorter than that in the control group[(9.8±3.9)h],the Apgar score of newborns[(9.4±0.3)points]was lower than that in the control group[(8.1±1.0)points],and the differences were statistically significant(P＜0.05).ConclusionThe humanized nursing appliedto maternal natural birth has the good clinical effect,which can effectively improve natural birth rate,and reduce postpartum hemorrhageamount,andbenefit the newborn,and improve nursing satisfaction,so it is worthyof clinical promotion.
2017 Vol. 24 (19): 187-189转193 [
Abstract
] (
155
)
HTML
(39 KB)
PDF
(0 KB) (
45
)
190
Application effect of integrated nursing model in patients with inguinal hernia surgery
ZHONG Hong-mei；DENG Yang-dan；ZHANG Hua-na
ObjectiveTo explore the application effect of integrated care model in the nursing of patients with inguinal hernia surgery,and to provide scientific and effective solutions for clinical nursing work.Methods 100 patients with inguinal hernia
received：
tension-free hernioplasty in our department from January 2015 to December 2016 were selected as the research objects and were divided into the control group and the observation group according to the random number table method.Patients in the control group(n=50)were given routine nursing intervention,while patients in the observation group(n=50)were given nursing intervention on the basis of the control group.The visual analogue scale(VAS)was used to assess the degree of pain,the Pittsburgh sleep quality index(PSOI)was used to determine the sleep quality of the patients.The VAS score,PSOI score,length of hospital stay and nursing satisfaction were compared between two groups.ResultsBefore nursing,there were no significant differences between the scores of VAS and PSOI in two groups(P＞0.05); after nursing,the scores of VAS and PSOI in two groups were all decreased,and compared with those before nursing,the differences were statistically significant(P＜0.01).And those in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.01).The length of hospital stay in the observation group were shorter than that in the control group,the nursing satisfaction was higher than that in the control group,and the differences were statistically significant(P＜0.01).ConclusionThrough the integration of medical and nursing intervention,the patients′pain is reduced,the hospitalization time is shortened,the sleep quality is improved,and the patient satisfaction is improved.
2017 Vol. 24 (19): 190-193 [
Abstract
] (
156
)
HTML
(36 KB)
PDF
(0 KB) (
51
)
194
Efficacy of telephone follow-up continuous nursing on recurrent febrile convulsion in children
YANG Yan-fei；LIN Shao-qun ；YE Xia； ZHOU Xue-xia
ObjectiveTo explore efficacy of telephone follow-up continuous nursing on recurrent febrile convulsion in children.Methods96 pediatric patients with febrile convulsion admitted to our hospital from January 2014 to June 2016 were selected and randomly divided into the observation group and the control group according to the random number table,with 48 cases in each group.The control group was given routine discharge instructions,and the observation group was given telephone follow-up continuous nursing in addition to routine discharge instructions.The awareness of the related knowledge among the patients′parents at 6 months post-discharge and the recurrence rate within 6 months were compared between two groups.ResultsThe score for awareness of related knowledge among patients′parents at discharge was(81.36±10.58)points in the observation group and(82.64±11.39)points in the control group,without statistically significant difference between the two groups(P＞0.05)；the score for awareness of related knowledge among patients′parents at 6 months post-discharge in the observation group [(93.34±6.85)points]was higher than that in the control group [(88.19±7.16)points],with statistically significant difference between the two groups(P＜0.05);the recurrence rate within 6 months in the observation group(6.25%)was lower than that in the control group(22.92%),with statistically significant difference between the two groups(P＜0.05).ConclusionTelephone follow-up continuous nursing is effective for raising the awareness of the related knowledge among parents of pediatric patients with febrile convulsion,thus reducing the recurrence rate.
2017 Vol. 24 (19): 194-196 [
Abstract
] (
147
)
HTML
(32 KB)
PDF
(0 KB) (
39
)
Copyright © Editorial Board of 中国当代医药
Supported by:
Beijing Magtech
