中国当代医药
      Home                              中文
中国当代医药
 
Forthcoming Articles
Current Issue
Archive
Advanced Search
Read Articles
Download Articles
Email Alert
 
Quick Search  
  Adv Search
2017 Vol. 24, No. 14
Published: 2017-05-18

 
 
4 Expression and clinical significance of homologous gene IRX1 in primary hepatocellular carcinoma
XU Hai-tao;LIU Liang-tian;TANG Yong-hua;LI Ping
ObjectiveTo explore the expression and clinical significance of homologous gene IRX1 in primary hepatocellular carcinoma.Methods30 patients with liver cancer who were treated by operation in People′s Hospital of Guangming New District in Shenzhen City and Shiyan People′s Hospital of Shenzhen City from May 2014 to May 2016 were selected as observation group,at the same period,30 volunteers or patients with benign liver diseases were selected as control group.Detection of mRNA transcription level and detection of IRX1 protein expression in liver tissue after IRX1 gene was prepared,and the differences of IRX1 expression were compared between the two groups.ResultsThe expression and transcription level of IRX1 protein in the liver tissue of the control group were significantly different from that of the control group (P<0.05).In the observation group,the expression of IRX1 protein in high,middle and low differentiation was 1.90 times,3.31 times and 3.33 times of control group respectively.In the observation group,high,middle and low differentiation transcription level was 2.95 times,1.83 times,4.46 times as compared with that in control group,the difference was statistically significant(P<0.05).The positive rate of IRX1 in the observation group was significantly higher than that in the control group,the difference was statistically significant(P<0.05).There was no significant difference of complications between the two groups(P>0.05).ConclusionIRX1 is involved in the incidence and devel opment process of hepatocellular carcinoma,and its expression is correlated with the degree of differentiation of liver cancer.IRX1 can be used as an indicator for judge the state of an illness in clinic.
2017 Vol. 24 (14): 4-6 [Abstract] ( 154 ) HTML (33 KB)  PDF  (0 KB)  ( 42 )
7 Correlation between vascular endothelial growth factor+936C/T polymorphism and colorectal cancer risk:a Meta analysis
ZHOU Chun-hua;YUAN Song-quan;LI Mei-zhen
ObjectiveTo investigate the association between the vascular endothelial growth factor(VEGF)gene+936C/T polymorphisms and colorectal cancer(CRC)risk.MethodsRelevant published case-control studies were searched in PubMed,Embase and Medline databases,and all documents were updated to October 2016.A comprehensive meta-analysis was then performed with Review Manager 4.2 and Stata 11.0 software in this work.ResultsFinally 10 studies including 2860 cases and 3080 controls were brought into our meta-analysis.The association between VEGF+936C/T polymorphisms and CRC risk were calculated with OR and their corresponding 95%CI,and stratified analysis was also conducted with respect to ethnicity.Combined analysis revealed that no significant association between VEGF+936C/T polymorphismandCRCriskwasidentifiedinallcomparisonmodelsincludingTallele vs.Callele[OR=1.04,95%CI(0.87,1.25), P=0.63],CT+TT vs.CC[OR=1.06,95%CI(0.86,1.30),P=0.61],TT vs.CC+CT[OR=1.10,95%CI(0.85,1.41),P=0.47],and TT vs. CC[OR=1.17,95%CI(0.91,1.52),P=0.22].Moreover,a similar result was obtained in the subgroup analysis that no significant association with CRC risk was found in all comparison models of VEGF+936C/T polymorphism in both Caucasian and Asian populations.ConclusionIt has been proved that VEGF+936C/T polymorphism might not be a risk factor for colorectal cancer,but further studies with larger sample sizes are required to make a better assessment of above association.
2017 Vol. 24 (14): 7-11转36 [Abstract] ( 152 ) HTML (50 KB)  PDF  (0 KB)  ( 38 )
12 Study process of surgical treatment of mixed hemorrhoids
DING Chao ;WANG Chen
Hemorrhoid is a common and prevalent disease in clinic.As for the treatment of Hemorrhoids,more than 80% of hemorrhoids just need conservative treatment in the modern idea.Only a few cases invalid by the conservative treatment,orⅢ,Ⅳdegree of hemorrhoids which having irreversible pathological anatomy and physiological function,then surgical operation is considered to use.The primary aim of the operation is eliminating lesions,relieving symptoms and reserving normal mucosa as much as possible.By searching and review the related literature at home and abroad in recent years,this article reviews some progresses in the surgical treatment of hemorrhoids in order to provide some reference and reference significance.
2017 Vol. 24 (14): 12-14 [Abstract] ( 156 ) HTML (36 KB)  PDF  (0 KB)  ( 35 )
15 The origin and inheritance of CHEN apitherapy
ZU Xiang-meng;WEI Yi-wei;CHEN Hai-yan;DENG Jing-xi;GUO Shen-guo;GUO Wen-chao;GUO Le;LIU Qi
As the fourth batch of provincial intangible cultural heritage representative program,CHEN apitherapy has been in inheritance for a long time and is a comparably more complete clinical diagnosis and treatment in the apitherapy field of traditional Chinese medicine.This has a close relationship with its unique theoretical system formed in the process of inheritance and development of its each inheritor.Sorting out the inheritance tree and academic theory system of CHEN apitherapy will contribute to its preservation and development.
2017 Vol. 24 (14): 15-17 [Abstract] ( 181 ) HTML (37 KB)  PDF  (0 KB)  ( 43 )
18 Treatment of intrahepatic bile duct stones with systemic liver segment under ultrasound guidance
LIAO Cheng-wen;ZHENG Ai-hua;ZHENG Hui-hua;LIU Da-mao
ObjectiveTo investigate the clinical effect of intraoperative ultrasonography in the treatment of intrahepatic bile duct stones by systematic hepatic segment resection.Methods48 patients with systemic hepatic resection were enrolled in our hospital from April 2014 to September 2016.The patients were divided into two groups:the control group (n=44)were treated with choledocholithotomy,the observation group(n=45)were underwent ultrasound-guided systemic liver resection,the effect in two groups were compared.Results①The intraoperative blood loss[(126.73±32.87)ml],the operation time[(82.25±3.17)min]and the hospitalization time[(9.72±1.63)d]were significantly lower than those in the control group[(289.95±21.39)ml,(138.63±19.25)min,(13.76±2.26)d](P<0.05).②The total effective rate was 93.33% in the observation group and higher than 72.73%in the control group.③The incidence of complication in the observation group(8.88%)was significantly lower than that of the control group(29.55%)(P<0.05).ConclusionUltrasound-guided treatment of intrahepatic bile duct stones in patients with systemic liver resection,can improve the removal rate of stones, shorten the recovery time of patients,and the safety is good,worthy of promotion.
2017 Vol. 24 (14): 18-20 [Abstract] ( 148 ) HTML (35 KB)  PDF  (0 KB)  ( 35 )
21 Clinical efficacy and effects on quality of life and self-rating scale of sleep laparoscopic surgery in the treatment of adhesive intestinal obstruction
SONG Guo-lang
ObjectiveTo discuss the clinical efficacy of laparoscopic surgery in the treatment of adhesive intestinal obstruction,and analysis the effect on quality of life and self-rating scale of sleep.MethodsA total of 62 patients with adhesive intestinal obstruction in our hospital from June 2014 to June 2016,which were numbered based on the time of admission,were randomly classified into two groups according to random number table,with observation group(n=31) treated with laparoscopic surgery,and control group(n=31)treated with laparotomy.Then the incidences of incision infection, intestinal fistula,urinary tract infection and recurrence were compared,and quality of life and self-rating scale of sleepstatus were analyzed.ResultsThe recurrence rate(0)and total complications incidence rate(3.2%)in observation group were markedly lower then those in control group(12.9%,25.8%)(P<0.05);the environmental status[(78.4±5.6)scores],social acceptability[(71.3±5.8)scores],physiological function[(67.5±5.7)scores],mental ability[(78.4±5.4)scores]of the observation group,were remarkably higher then those in control group[(65.1±5.4),(61.8±5.6),(57.2±4.3),(66.1±5.9)scores](P<0.05);the score of each item of SRSS in observation group were statistically lower then those in control group,(P<0.05)。ConclusionThe laparoscopic surgery has significant clinical effect in the treatment of adhesive intestinal obstruction, and can improve quality of life and sleep status.
2017 Vol. 24 (14): 21-23 [Abstract] ( 146 ) HTML (32 KB)  PDF  (0 KB)  ( 36 )
24 Application of sequential non-invasive mechanical ventilation in pulmonary rehabilitation of patients with stable severe COPD
PENG Yong-sheng;LAI Yong-hui;ZHU Qi-cheng
ObjectiveTo investigate the clinical effect of sequential non-invasive mechanical ventilation in pulmonary rehabilitation of patients with stable chronic obstructive pulmonary disease(COPD).MethodsA total of 80 patients with stable severe COPD treated in our hospital from November 2011 to November 2016 were randomly divided into the observation group(n=40,given routine pulmonary rehabilitation combined with sequential noninvasive mechanical ventilation treatment)and the control group(n=40,given routine pulmonary rehabilitation).Pulmonary function,blood gas analysis indexes and quality of life were compared between the two groups.ResultsAfter treatment,the levels of FEV1/FVC, PaO2,PaCO2,pH and RR in the observation group were significantly better than those before treatment,and the improvement was better than that in the control group(P<0.05).After treatment,QOL score,6 MWD and Borg score in the observation group were significantly better than those before treatment,and the improvement was better than that in the control group(P<0.05).ConclusionSequential non-invasive mechanical ventilation combined with pulmonary rehabilitation therapy can significantly improve lung function in patients with stable severe COPD and hypoxia symptoms,regulating acid-base balance,improve the life quality of patients and endurance activities,and is worthy of popularization.
2017 Vol. 24 (14): 24-26 [Abstract] ( 158 ) HTML (32 KB)  PDF  (0 KB)  ( 10 )
27 Research on effect of bilateral craniotomy bone flap decompression treating severe craniocerebral injury
LI Wei-jun
ObjectiveTo explore the effect of bilateral craniotomy bone flap decompression treating STBD.Methods45 patients with severe craniocerebral injury treated in our hospital from January 2012 to June 2014 were selected as the control group,and 45 cases with severe craniocerebral injury treated in our hospital from September 2014 to March 2017 were selected as the observation group.The clinical data of two groups was analyzed retrospectively.The control group was treated with the conventional unilateral craniotomy,and the observation group was treated with bilateral craniotomy bone flap decompression.ResultsAfter treating with different methods,the good recovery condition after operation of the observation group was better than that of the control group.For the improve condition of GCS score,there was no evident difference for GCS score before operation between two groups(P>0.05).After treating with different methods, GCS score of the observation group was(10.22±0.99)scores,and that of the control group was(6.77±1.65)scores.The difference between two groups was evident(P<0.05).ConclusionApplying bilateral craniotomy bone flap decompression to treat STBD not only can evidently improve the life quality of patients and reduce the mortality rate,but also achieves better treatment effect,which is worthy of promotion and application in clinical practice.
2017 Vol. 24 (14): 27-29 [Abstract] ( 174 ) HTML (32 KB)  PDF  (0 KB)  ( 62 )
30 Effect of blood purification therapy (CRRT)on patients with multiple organ dysfunction syndrome(MODS)and its relationship with prognosis
REN Yan-hua ;CAI Ying-li;LI Hai-bin; GAO Ming-xia; LI Zhong-zhan
ObjectiveTo investigate the effect of blood purification therapy(CRRT)on patients with multiple organ dysfunction syndrome (MODS)and its prognosis.Methods40 patients with multiple organ dysfunction syndrome from June 2015 to June 2016 were divided into two groups:observation group and control group.20 samples were obtained from each group.The control group was given the patients were treated with routine blood therapy,and the patients were treated with blood purification treatment.The treatment effect,hospitalization time,improvement of heart rate,improvement of psychiatric symptoms and improvement of gastrointestinal function were observed and analyzed.ResultsThe total effective rate of the treatment group was higher than that of the control group.The hospitalization time was significantly shorter than that of the control group.The improvement of heart rate,improvement of psychiatric symptoms and improvement of gastrointestinal function were better than those of the control group(P<0.05),the improvement of heart rate,the improvement of psychiatric symptoms and the improvement of gastrointestinal function were statistically significant (P<0.05).ConclusionThe treatment of multiple organ dysfunction syndrome patients with blood purification treatment, treatment effect is outstanding,shorter hospital stay,heart rate,mental symptoms and gastrointestinal function improved better,worthy of clinical reference.
2017 Vol. 24 (14): 30-32 [Abstract] ( 149 ) HTML (33 KB)  PDF  (0 KB)  ( 41 )
33 Clinical observation of intestine microecologic agents in the treatment of dialysis constipation
ZHOU Yang; SHEN Jiang-shan;YIN Jin-feng
ObjectiveTo exploring methods for the treatment of long-term dialysis patients with constipation.Methods52 cases of patients with chronic kidney disease(CKD)5 were selected,who were taken with maintenance hemodialysis treatment in our hospital from Delember 2015 to Delember 2016,were treated with oral bifidobacterium triple viable enteric capsules for 4 weeks,the stool frequency,character of stool integral,and defecate difficulty were compared between before and after treatment.ResultsAfter treatment for 2 weeks and 4 weeks compared with before treatment,the patient′s stool frequency and defecate difficulty points were obviously increased,the defecate difficulty points were significantly dropped,the difference was statistically significant(P<0.05).But 4 weeks after treatment compared with 2 weeks after treatment,only defecate difficulty point was statistically significant(P<0.05).ConclusionIntestine microecologic agents can treat dialysis patients with chronic constipation safly and effectively.
2017 Vol. 24 (14): 33-36 [Abstract] ( 151 ) HTML (41 KB)  PDF  (0 KB)  ( 30 )
37 Feasibility analysis of continuous renal replacement therapy for severe sepsis
OU Yuan ;WANG Ling
ObjectiveBy observing the clinical effect of continuous renal replacement therapy in patients with severe sepsis to analysis the feasibility of continuous renal replacement for severe sepsis.Methods13 patients with severe sepsis who received:continuous renal replacement therapy in our hospital from March 2015 to March 2016 were selected as observation group,13 patients with severe sepsis who had undergone continuous renal replacement therapy without conventional therapy were selected as the control group,the clinical data of the two groups were recorded before and after treatment,including lactic acid,procalcitonin,oxygenation index,urine output and so on,to compare the treatment and mortality of two groups.ResultsThere was a significant difference between the two groups in the severity of disease(APCHEⅡ score)and organ failure(SOFA score),the difference was not statistically significant(P>0.05);Comparison of the two groups of patients in the short term lactate,procalcitonin decreased,increased oxygenation index and urine recovery,the observation group was significantly better,their difference was statistically significant(P<0.05);The mortality rate in the acute phase (7 days)was 7.69%,and significantly decreased compared with the control group (38.46%),the difference was statistically significant(P<0.05).ConclusionContinuous renal replacement therapy can improve the success rate of acute sepsis in patients with severe sepsis,has a certain feasibility,can be applied in clinical practice.
2017 Vol. 24 (14): 37-39 [Abstract] ( 158 ) HTML (33 KB)  PDF  (0 KB)  ( 37 )
40 The Prevalence and Risk factor analysis of fatty liver disease in Shantou Health Examination Crowd
YAO Ying-hua;ZHENG Qiang
ObjectiveTo know shantou health examination crowd incidence of fatty liver and its major risk factors,to explore the epidemiological characteristics and to provide evidence for the prevention of fatty liver.MethodsA complete data including 1916 cases of medical test results were collected between December 2009 and November 2011 in Shantou Hospital of TCM analysis the prevalence of fatty liver and related risk factors.ResultsThe incidence of fatty liver was 47%,the incidence of male was significantly higher than female (P<0.01).Age,BMI,DPB,TG,ALT,AST,FPG, TBIL,DBIL values in fatty liver group were significantly higher than those in non-fatty liver group(P<0.05).The Logistic regression analysis results showed that BMI,FPG,TG,TC,ALT,AST were risk factors of fatty liver disease(P<0.05).ConclusionThe incidence of fatty liver in Shantou health examination crowd is higher and associated with obesity,blood glucose,blood lipid and liver function closely.
2017 Vol. 24 (14): 40-42 [Abstract] ( 147 ) HTML (34 KB)  PDF  (0 KB)  ( 36 )
43 Application of PTCD and ERCP in the treatment of obstructive jaundice
XIONG Xiang
ObjectiveTo research the application of PTCD and ERCP in the treatment of obstructive jaundice.Methods36 cases with obstructive jaundice in our hospital from January 2014 to December 2016 were selected as research objects and then they were divided into two groups according to physical conditions of patients and the principle of voluntariness,18 cases in each group.Treated with Percutaneous Transhepatic Choledochus Drainage (PTCD)in the PTCD group and treated with Endoscopic Retrograde Cholangiopancreatography (ERCP)in the ERCP group.The clinical effects of patients were compared in pairs.ResultsIn the treatment of benign obstructive jaundice,thedeclining level of 5 d serum total bilirubin and the complication occurring rate after operation in ERCP group were better than that in the PTCD group,the difference between the two groups was statistically significant(P<0.05).The operative success rates of two groups had no significant differences(P>0.05).In the treatment of malignant obstructive jaundice,the operative success rate and declining level of 5 d serum total bilirubin after operation in PTCD group were better than ERCP group, the difference between the two groups was statistically significant(P<0.05).The complication occurring rates of two groups had no significant differences(P>0.05).ConclusionERCP and PTCD have their own advantages.In the clinical treatment, the reasonable choice should be made based on the actual conditions of patients to improve the clinical effects of treatment.
2017 Vol. 24 (14): 43-45 [Abstract] ( 181 ) HTML (31 KB)  PDF  (0 KB)  ( 31 )
46 Effect of fluprofen tromethamine for refractory non-erosive gastroesophageal reflux disease
LIU Feng;LI Jun
ObjectiveTo investigate the clinical effect of fluprofen tromethamine for refractory non-erosive gastroesophageal reflux disease.Methods80 cases with refractory non-erosive gastroesophageal reflux disease from January 2015 to January 2017 were randomly divided into two group,each 40 cases.The control group were treated with rabbits and the observation group were used flupaphene tromethamine tablets,and all were taken for 8 weeks for a course,then tolerance(RDQ)questionnaire,24 h and 48 h after treatment,pH values,adverse reactions and total hospital stay were compared.ResultsThe RDQ scores with heartbeat,posterior sternal pain,acid reflux and belching in the observation group were significantly lower than control group (P<0.05),the pH value in the observation group with 24 h and 48 h were significantly higher than control group (P<0.05).There had no significant difference in the incidence with dry mouth,tachycardia and vertebral body reaction between the two group (P>0.05),the hospital stay time in the observation group was significantly shorter than control group (P<0.05).ConclusionFor the treatment of refractory non-erosive gastroesophageal reflux disease,the treatment with fenaprozethillin can relieve the clinical symptoms and improve the pH value in the stomach and short the hospitalization time and the treat has less adverse reactions,so it is safe.
2017 Vol. 24 (14): 46-48 [Abstract] ( 167 ) HTML (36 KB)  PDF  (0 KB)  ( 37 )
49 A study between ferritin and insulin resistance and its sex differences in type 2 diabetes mellitus
ZHANG Wei
ObjectiveTo investigate the correlation between serum ferritin(SF)and insulin resistance and its sex differences in patients with type 2 diabetes mellitus(T2DM).Methods49 patients with T2DM treated in our hospital of department of endocrinology from July 2014 to December 2015 were selected.According to the sex,patients were divided into the male group including 25 patients and the female group including 24 patients.50 healthy subjects receiving physical examination at the same period were included in the control group.Total cholesterol(TC),triglyceride (TG),low-density lipoprotein-cholesterol(LDL-C),high-density lipoprotein-cholesterol(HDL-C),C-reactive protein(CRP),HbA1c,fasting insulin(FINS),SF,and fasting plasma glucose(FPG)were detected in various group.ResultsTC,TG,LDL-C,HDL-C,CRP, HbA1c,FBG,FINS,SF,and homeostasis model assessment-insulin resistance(HOMA-IR)were significantly higher in the T2DM group than in the control group(P<0.05).SF presented positive correlation with TC,TG,LDL-C,and FBG(P<0.05), and significant positive correlation with HbA1c,HOMA-IR,FINS,and CRP(P<0.01).The correlation between HOMA-IR and SF was higher in male patients than in female patients with T2DM.ConclusionSF is elevated in patients with T2DM,and to some extent correlated with insulin resistance.The correlation between HOMA-IR and SF in male patients is more better.
2017 Vol. 24 (14): 49-51 [Abstract] ( 145 ) HTML (32 KB)  PDF  (0 KB)  ( 40 )
52 Effect of Telmisartan on the level of serum Omentin and IL-18 in the aged diabetic patients with hypertesion
LI Zhao-lei;YUE Wei;WANG Hong;SUN Wei;CUI Qiu-zi;CHAI Guo-lu
ObjectiveTo study the changes of serum Omentin,IL-17 and IL-18 level,to studay the possible effect of of serum Omentin,IL-17 and IL-18 change in the develpment of hypertension,to investigate the effect of Telmisartan on the level of serum Omentin,IL-17 and IL-18 in the aged diabetic patients with hypertension.Methods126 aged patients with type 2 diabetes mellitus were selected from January 2015 to June 2016 in our hospital,and they were divided into two group:72 cases of type 2 aged diabetic patients with hypertension (diabetic patients with hypertension group) and 54 cases of type 2 aged diabetic patients with normal blood pressure (diabetic patients with normal blood pressure group).30 cases of normal aged individuals with physical examination during the same period were as the control group (control group).The level of serum Omentin,IL-17 and IL-18 were measured in the three groups.The relatoinshp between the serum Omentin level and serum IL-17,IL-18 level were analyzed in the aged diabetic patients with hypertension.The change of seroum Omentin,IL-17and IL-18 level were investigated in the aged diabetic patients with hypertension after treatment with Telmisartan.ResultsSerum Omentin level in the aged diabetic patients with hypertension group was significantly lower than those in the diabetic patients with normal blood pressure group,the serum IL-17 and IL-18 level in the aged diabetic patients with hypertension group were significantly higher than those in the aged diabetic patients with normal bloodpressure group,the differences were statistically significant(P<0.01).A negtive correlation was found between serum Omentin level and serum IL-17,IL-18 level in the aged diabetic patients with hypertension group (r=-0.527,r=-0.602, P<0.01).Serum Omentin level was significantly increased,the levels of IL-17 and IL-18 were significantly decreased after treatment with Telmisartan in the aged diabetic patients with hypertension group,the differences were statistically significant(P<0.01).ConclusionThe low serum level of Omentin and increased serum level of IL-17,IL-18 might play an important role in the development of hypertension in the aged diabetic patients.The serum Omentin level was significantly increased,the level of IL-17 and IL-18 were significantly decreased after treatment with Telmisartan in the aged diabetic patients with hypertension.
2017 Vol. 24 (14): 52-55 [Abstract] ( 172 ) HTML (40 KB)  PDF  (0 KB)  ( 42 )
56 Clinical observation of vacuum sealing drainage combined with medical three oxygen water repairing the wound surface of diabetic foot
WANG Hong-bin;CHENG Jie
ObjectiveTo evaluate the effect of vacuum sealing drainage(VSD)combined with medical three oxygen water treating the wound surface of diabetic foot.Methods56 hospitalized patients diabetic foot meeting the inclusion criteria in Department of Endocrinology of Wuhai People′s Hospital in Inner Monggol Autonomous Region from July 2013 to July 2016 were collected.Patients were randomly divided into the routine group (20 patients),the control group(17 patients)and the observation group (19 patients).The routine group was given the routine VSD combined with normal saline flushing,the control group was given the routine VSD combined with oxygen-containing fluid flushing,while the observation group was given the routine VSD combined with medical three oxygen water flushing.The general situation of the wound,the number of bacteria in the wound,the blocking rate of the drainage tube,the coverage rate of granulation tissue,the partial pressure of oxygen in the local tissue of the wound and the survival rate of the second stage wound healing were observed and measured.ResultsThe general situation of the wound showed that necrotic tissues were found on the wound surface of patients in three groups before debridement having no or a few of granulation tissues.After treatment for 7 days,necrotic tissue were significantly reduced and granulation tissue were significantly increased in three groups,but the degree of improvement in the observation group,the control group and the conventional group was slightly worse.Drainage tube blockage rate among three groups was not statistically significant(F=2.21,P>0.05),wound coverage rate of granulation tissue,local tissue oxygen pressure of wound,wound bacterial clearance rate and the survival rate of wound repairing at phase-II was statistically significant(F=19.58,86.52,30.47,10.34,P<0.01).ConclusionVSD combined with medical three oxygen water can accelerate the wound healing of diabetic foot,reduce wound infection and improve the quality of phase-II surgery.
2017 Vol. 24 (14): 56-58转64 [Abstract] ( 136 ) HTML (35 KB)  PDF  (0 KB)  ( 42 )
59 Value of serum CRP and PCT in assessment of severity and prognosis of diabetic foot infection
LI Chang-lin;ZOU-Xu;ZHU Huan-jin;XIE Yue
ObjectiveTo explore the value of serum procalcitonin(PCT)and C-reaction protein(CRP)in assessment of severity and prognosis of diabetic foot infection.Methods165 cases with diabetic foot infection treated in our hospital from January 2015 to January 2017 were selected as objects,and all patients were divided into the mild infection group with 45 cases,the moderate infection group with 93 cases,and the severe infection group with 27 cases according to the severity of the infection,the enrolled patients were divided into cured group(n=63),the improved group(n=78),and the ineffective group(n=23)according to the curative effect of diabetic foot.The level of PCT and CRP were determined in various group.ResultsThe level of PCT and CRP in the mild group were lower than those in the moderate group and the severe group(P<0.05).The level of PCT and CRP in the moderate group were lower than those in the severe group(P<0.05).The level of PCT and CRP of the three groups were remarkably lower after treatment than before treatment(P<0.05).The level of PCT and CRP in the cured group were lower than those in the improved group and the ineffective group after the treatment(P<0.05).The level of PCT and CRP in the improved group were lower than those in the ineffective group (P<0.05).ConclusionSerum PCT and CRP have certain clinical value in assessment of severity and prognosis of diabetic foot infection.
2017 Vol. 24 (14): 59-61 [Abstract] ( 127 ) HTML (31 KB)  PDF  (0 KB)  ( 39 )
62 Diagnostic value of endoscopic NBI technique in early gastric cancer
ZHAI Jun-hou
ObjectiveTo study the diagnostic value of endoscopic narrow band imaging (NBI)in early gastric cancer.MethodsFrom January 2013 to August 2015,80 cases of early gastric cancer patients in our hospital were selected,and ordinary white light endoscopy,NBI magnification endoscopy were given.The diagnostic results of two methods were compared according to the standard of pathological results.ResultsThe sensitivity,specificity and histopathological findings of NBI examination method was significantly higher than that of ordinary white endoscopy,with significant difference(P<0.05).The image quality score of contours of the lesion,the morphology of the pueraria and microvascular morphology of the NBI examination method was significantly higher than that of the ordinary white endoscopy,with significant difference(P<0.05).ConclusionIn the digestive medicine,NBI diagnosis of patients can accurately identify the early gastric cancer and precancerous lesions,which is conducive to the diagnosis and treatment as soon as possible,it is worthy of clinical promotion application.
2017 Vol. 24 (14): 62-64 [Abstract] ( 150 ) HTML (29 KB)  PDF  (0 KB)  ( 33 )
65 Clinical efficacy and safety analysis of laparoscopic assisted vaginal surgery and simple laparoscopic surgery in the treatment of endometrial carcinoma
XU Li;HUANG Si-min
ObjectiveTo observe the clinical efficacy and safety of laparoscopic assisted vaginal surgery and simple laparoscopic surgery in the treatment of endometrial carcinoma.Methods86 patients with endometrial carcinoma admitted in our hospital from January 2011 to January 2012 were selected as the study subjects.According to the different methods of operation,the patients were divided into the control group and the observation group,43 cases in each group.The control group was treated with simple laparoscopic surgery,and the observation group was treated with laparoscopic assisted vaginal surgery.The clinical effect and the postoperative complications of the two groups were compared.ResultsThe operation time,intraoperative blood loss,catheter retention time,exhaust time,lymph node clearance number and hospitalization time in the observation group was better than that in the control group,with significant difference(P<0.05).The incidence rate of postoperative complications in the observation group was 4.65%,which was lower than that of the control group(16.28%),with significant difference(P<0.05).The survival rate at 1,2,3 years of the observation group(93.02%, 83.72%69.77%)was higher than that of the control group(79.07%,65.12%,48.84%),with significant difference(P<0.05).ConclusionThe clinical effect of laparoscopic assisted vaginal surgery in the treatment of endometrial carcinoma is superior to that of laparoscopic surgery alone.It has the advantages of small surgical trauma,quick recovery and good safety.It is worthy of clinical promotion and application.
2017 Vol. 24 (14): 65-67转96 [Abstract] ( 131 ) HTML (36 KB)  PDF  (0 KB)  ( 37 )
68 Effect of Mirena in the treatment of complex endometrial hyperplasia
ZHANG Ji;LI Xue-nian ;HUANG Ping;WANG Ling
ObjectiveTo explore the clinical effect of Mirena in the treatment of complex endometrial hyperplasia.MethodsFifty patients with complex endometrial hyperplasia treated in our hospital from January 2014 to March 2016 were evenly assigned to the two groups according to the parity of the admission order:observation group(even)and control group (odd).The control group was given routine treatment,the observation group was given the conventional treatment based on the use of Mirena treatment.The pathological changes of endometrium were observed by hysteroscopy before treatment,and after 3,6,9 months of treatment,and the clinical effect of treatment was evaluated.ResultsAfter 3,6,9 months of treatment,hemoglobin,menstrual score,and endometrial thickness was better than that before treatment,and over time,the indicators was better than the previous one(P<0.05).After 3,6,9 months of treatment,the indexes of the observation group were better than those of the control group,the differences were statistically significant(P<0.05).The total effective rate was 96.00%in the observation group,was higher than 68.00%in the control group,the difference was statistically significant(P<0.05).ConclusionThe effect of using Mirena is significant in the treatment of complex endometrial hyperplasia,and it has obvious effect in improving the hemoglobin value,menstrual score and endometrial thickness.It has clinical application and popularization value.
2017 Vol. 24 (14): 68-70 [Abstract] ( 167 ) HTML (32 KB)  PDF  (0 KB)  ( 18 )
71 Effect observation of electrical stimulation biofeedback therapy combined with self consolidating training on the rehabilitation of pelvic floor muscle function in postpartum women
ZHOU Zu-mei;XU Qing-yun ;MO Jie-zhen
ObjectiveTo observe the effect of electrical stimulation biofeedback therapy combined with self consolidating training on the rehabilitation of pelvic floor muscle function in postpartum women.Methods120 cases of primiparas were selected,who were hospitalized in Yangjiang Maternal and Child Health Care Hospital of Guangdong Province from September 2015 to September 2016,volunteered for the detection of pelvic floor and pelvic floor rehabilitation therapy, the primiparas were divided into observation group(60 cases)and control group(60 cases)according to whether use the self consolidating training during the treatment of electrical stimulation biofeedback therapy.The observation group was divided into observation group 1(30 cases)and observation group 2(30 cases);the observation group 1 was treated by electrical stimulation biofeedback therapy combined with pelvic floor muscle exercise,the observation group 2 was treated by electrical stimulation biofeedback therapy combined with vaginal dumbbell training;while the control group was only accepted electrical stimulation and biofeedback therapy.The pelvic electrical diagnosis was used in each groups before and after treatment,the pelvic floor muscle fiber,the maximum muscle voltage ofⅠ,Ⅱpelvic floor muscle and fatigue state were compared and analyzed.ResultsAfter rehabilitation treatment,muscle strength and the maximum muscle voltage ofⅠ,Ⅱpelvic floor muscles of the observation group and control group were higher,and the mean value of fatigue were lower;the differences before and after treatment intra-group had statistical significance (P<0.05).Curative effect in the observation group was better than that in the control group,the difference had statistical significance(P<0.05);curative effect in the observation group 2 was better than that in the observation group 1,the difference had statistical significance(P<0.05).ConclusionElectrical stimulation biofeedback therapy combined with self consolidating training can improve the curative effect of rehabilitation of pelvic floor muscle function in primiparas;compared with pelvic floor muscle exercise,the vaginal dumbbell training has better curative effect in the electrical stimulation biofeedback therapy.
2017 Vol. 24 (14): 71-75 [Abstract] ( 118 ) HTML (49 KB)  PDF  (0 KB)  ( 41 )
76 Clinical study of laparoscopic assisted vaginal hysterectomy for the treatment of giant uterine leiomyoma
MIN Li
ObjectiveTo study the clinical efficacy of laparoscopic assisted vaginal hysterectomy in the treatment of patients with giant uterine fibroids.MethodsFrom June 2014 to June 2016,90 cases with giant uterine leiomyoma in our hospital were divided into two groups by random number table method,45 cases in each group.The experimental group was treated by laparoscopic assisted vaginal hysterectomy,while the control was treated by laparotomy hysterectomy. The therapeutic effect of two groups was observed,and the operation time,ambulation time,postoperative anal exhaust time and hospitalization time were compared.ResultsBleeding and wound healing rate in the two groups had no significant difference(P>0.05),while the hospital time,operation time,anus exhaust time,ambulation time of the experimental group was respectively significantly shorter than that of the control group,rate of postoperative fever of the experimental group was lower than that of the control group,the differences were statistically significant(P<0.05);the incidence of postoperative complications in the two groups had no significant difference (P>0.05).ConclusionThe use of giant uterine fibroids patients undergoing laparoscopic assisted vaginal hysterectomy treatment can effectively reduce the impact on the patient,also can achieve significant clinical effect,is conducive to the recovery of patients,worthy of clinical application
2017 Vol. 24 (14): 76-78 [Abstract] ( 134 ) HTML (31 KB)  PDF  (0 KB)  ( 36 )
79 Effect of Clomiphene citrate direct ovulation plus ethinylestradiol cyproterone acetate in the treatment of polycystic ovary syndrome
CHEN Xiu-hua
ObjectiveTo investigate the clinical effect of Clomiphene citrate direct ovulation combined with ethinyl estradiol cyproterone acetate in the treatment of polycystic ovary syndrome (PCOS).Methods86 patients with PCOS treated in our hospital from January 2015 to August 2016 were randomly divided into observation group and control group according to the ratio of 1∶1,and the control group was treated with Clomiphene direct ovulation induction therapy,the observation group was treated with the Clomiphene based on the addition of ethinylestradiol cy proterone treatment.The levels of serum sex hormones,the number of mature follicles,endometrial thickness,cervical mucus score,ovulation rate and pregnancy rate were compared between the two groups.ResultsAfter 3 months of treatment,the levels of LH,FSH,T and E2were significantly lower in the observation group than those in the control group,the differences were statistically significant(P<0.05);the number of mature follicles,endometrial thickness and cervical mucus score of the observation group were better than those of the control group,the differences were statistically significant(P<0.05);the ovulation rate and pregnancy rate of the observation group were significantly higher than those of the control group,the differences were statistically significant(P<0.05).ConclusionThe application of Clomiphene citrate direct ovulation method in the treatment of PCOS based on the addition of ethinylestradiol cyproterone acetate can effectively improve the ovulation rate of patients,reduce the level of sex hormones in patients to promote pregnancy success,with good clinical reference value.
2017 Vol. 24 (14): 79-81 [Abstract] ( 182 ) HTML (33 KB)  PDF  (0 KB)  ( 34 )
82 Comparison of the effects of conventional therapy and Budesonide inhalation in the treatment of pneumonia in children
HU Ting ;ZHONG Liang ;LI Hao-hua ;YANG Wei-si;XU Bai-hua
ObjectiveTo explore the value of routine therapy and Budesonide inhalation therapy in children with pneu monia.Methods400 children with infantile pneumonia in our hospital from January 2010 to January 2016 were selected as the study objects,according to the different treatment methods they were divided into two groups,200 cases in the control group were received:conventional therapy,200 cases of the experimental group was received Budesonide inhalation treatment,the treatment outcome of the two groups was compared.ResultsThe total efficiency of the experimental group (94.00%)was significantly higher than the control group (65.00%),the difference was statistically significant(P<0.05);inflammatory factors of the experimental group compared with the control group,the difference was statistically significant (P<0.05);disappeared time of cough,fever,pulmonary rales of children in the experimental group was significantly shorter than the control group,the difference was statistically significant(P<0.05);there was no obvious adverse reaction in the two groups.ConclusionBudesonide inhalation in treatment of pediatric pneumonia curative effect is superior to conventional therapy,can effectively inhibit inflammatory reaction,shorten the duration of remission of symptoms,and has high security.
2017 Vol. 24 (14): 82-84 [Abstract] ( 128 ) HTML (34 KB)  PDF  (0 KB)  ( 37 )
85 Clinical comparison of laparoscopic surgery combined with Triptorelin or Gestrinone in the treatment of endometriosis
ZHANG Xiao-lin
ObjectiveTo compare the clinical effects of laparoscopic surgery combined with Triptorelin or Gestrinone in the treatment of endometriosis.Methods70 patients with endometriosis in our hospital from September 2015 to November 2016 were selected as research object.All the patients were divided into two groups by random number table,35 cases in each group.Patients of the two groups were given laparoscopic surgery,after surgery,observation group was given intramuscular injection of Triptorelin,control group was given Gestrinone orally.All the patients were given 5-month follow-up.The clinical efficacy,treatment situation,incidence of adverse reactions and recurrence rate of two groups were compared.ResultsThe curative effective rate of observation group was94.29%,which was significantly higher than 71.43%of the control group(P<0.05);the recovery time of menstruation and ovulation of the observation group were shorter than those of the control group (P<0.05);the total incidence of adverse reactions and recurrence rate of observation group(11.43%,5.71%)were lower than those of the control group(31.43%,22.86%),the differences were statistically significant(P<0.05).ConclusionCompared with Gestrinone,laparoscopic surgery combined with Triptorelin in the treatment of endometriosis has more significant clinical effects,with high safety and low recurrence rate,promote prognostic recovery,which is worthy of promotion in clinical application.
2017 Vol. 24 (14): 85-87 [Abstract] ( 146 ) HTML (32 KB)  PDF  (0 KB)  ( 39 )
88 Effect of Budesonide combined with Salbutamol inhalation combined with Montelukast in the treatment of infants with asthmatic bronchitis
YANG Ji-hong
ObjectiveTo study and explore the clinical effect of oral administration of Montelukast in the treatment of atomization and inhalation of infantile asthmatic bronchitis.Methods100 children with asthmatic asthmatic bronchitis who enrolled in our pediatric outpatient department from January 2013 to October 2016 were selected as research object,the subjects were randomly divided into two groups by single blind random grouping method,50 cases in the control group was treated with inhalation of Budesonide and Salbutamol,50 cases in the observation group was treated with Montelukast oral treatment which based on the control group,the asthmatic bronchitis clinical treatment effect,symptom relief time,outpatient treatment time and the incidence of adverse reactions were compared between two groups.ResultsThe total effective rate of treatment in the observation group (96%)was significantly higher than that in the control group(80%),the difference was statistically significant(P<0.05);symptom relief time of respiration[(4.10±1.85)d],cough [(2.01±0.96)d],wheeze[(4.59±1.94)d]and outpatient treatment time[(6.13±1.72)d]of the observation group was significantly shorter than that in the control group [(6.73±2.42),(3.36±1.28),(7.23±2.60),(8.49±2.38)d]respectively,the dif ference was statistically significant(P<0.05);the incidence of adverse reactions was 8%in the observation group and 6% in the control group,there was no significant difference between the two groups(P>0.05).ConclusionIn the treatment of children with asthmatic bronchitis,oral Montelukast treatment can effectively improve the effect of children inhalation therapy,promote its clinical symptoms more effectively,and with less adverse reactions,the safety is reliable.
2017 Vol. 24 (14): 88-90 [Abstract] ( 175 ) HTML (32 KB)  PDF  (0 KB)  ( 46 )
91 Analysis of screening results of retinopathy of premature babies
LIN Hai-bo ;LI Wen-lin ;ZHUO Xiao; CHEN Mu-dan; ZENG Ai-neng
ObjectiveTo analyze the incidence of retinopathy of premature babies(ROP)in this area and to explore the related factors so as to provide the basis for establishing screening criteria for retinopathy of premature babies.Methods438 premature infants with ROP screening criteria in our hospital from January 2015 to December 2016 were screened and the detection of ROP was analyzed.The detection of ROP in preterm infants with different birth weight and gestational weeks were analyzed and compared.ResultsThe detection rate of ROP in this area was 12.10%,and there was significant difference in the detection rate of ROP in different body weight range(χ2=33.973,P=0.000).Children with ROP were mainly in preterm infants with birth weight less than 1500 g.There was significant difference in the ROP detection rate in different birth weeks(χ2=30.643,P=0.000),and the prevalence of ROP was higher in preterm infants within 30 weeks.ConclusionThe prevalence rate of ROP is closely related to the birth weight and gestational age of pregnancy.The lower the birth weight is,the shorter the gestational age is and the higher the prevalence rate is.
2017 Vol. 24 (14): 91-93 [Abstract] ( 145 ) HTML (35 KB)  PDF  (0 KB)  ( 31 )
94 Comparative study on the clinical efficacy of different desensitizers in the treatment of dentin hypersensitivity after subgingival scaling of the root surface planing
YAN Xiang-ren; HONG Zhuo-zhuo; HUO Xiao-ling
ObjectiveTo investigate the effect of different desensitizers in the treatment of dentin hypersensitivity after subgingival scaling of the root surface planing.Methods150 cases of dentin hypersensitivity after subgingival scaling of the root surface planing from March 2015 to September 2016 in our hospital were selected and randomly divided into the experimental group(n=38)and the control group(n=37),75 cases in each group.The experiment group was treated with Gluma treatment,the control groupwas treated with oral desensitized paste treatment.The clinical efficacy of 15 min,1 month,and 3 months after treatment were compared between the two groups.ResultsThe total effective rate of 15 min,1 month,and 3 months after treatment in the experiment group was higher than that in the control group,with significant difference(P<0.05).ConclusionGluma treatment in dentin hypersensitivity after subgingival scaling of the root surface planing is better than that the oral desensitized paste treatment,and has the guiding sense to the clinical.
2017 Vol. 24 (14): 94-96 [Abstract] ( 131 ) HTML (32 KB)  PDF  (0 KB)  ( 38 )
97 Application efficacy of periodontal initial therapy combined with orthodontic treatment for periodontal disease
LIANG De-feng ;ZHOU Xin-cai;WEI Di-xin
ObjectiveTo compare the curative effects of simple periodontal initial therapy and combined orthodontic treatment for periodontal disease.MethodsFrom October 2015 to October 2016,68 periodontal disease patients were selectes and randomly divided into the simple treatment group and the combined treatment group,each group contained 34 patients.Patients in the simple treatment group were treated with simple periodontal initial therapy.The combined treatment group was treated by periodontal initial therapy combined with orthodontics treatment.The curative effect index,such as gingival index(GI),bleeding on probing(BOP),probing depth(PD),tooth mobility(TM)and alveolar bone density (ABD),and the aesthetical index such as dental aesthetic index (DAI),measured value of smile photograph and patient satisfaction were evaluated.ResultsThe GI,BOP,PD and TM after treatment in the two groups was lower than that before treatment,with significant difference(P<0.05).There was no significant difference in the GI after treatment between the two groups(P>0.05).The BOP,PD and TM after treatment in the combined treatment group was lower than that in the simple treatment group,with significant difference (P<0.05).The ABD after treatment in the combined treatment group was significantly higher than that before treatment and in the simple treatment group after treatment,with significant difference(P<0.05).The improvement of aesthetic index after treatment of the combined treatment group was better than that before treatment and of the simple treatment group,with significant difference (P<0.05).ConclusionThe combined orthodontic treatment for periodontal disease can significantly reduce periodontal inflammation,tooth mobility and the destruction in alveolar bone,obviously improve the dental esthetics of patients,it is worthy of promotion.
2017 Vol. 24 (14): 97-99 [Abstract] ( 133 ) HTML (36 KB)  PDF  (0 KB)  ( 35 )
100 Application of Flurbiprofen Axetil combined with lateral recess block in preemptive analgesia in elderly patients undergoing the orthopedics operation of lower limb
ZENG Jian-feng;HUANG Zhi-si;LIU Jiang-mei;HU Zhao-yun;TANG Chao
ObjectiveTo observe the application effect of Flurbiprofen Axetil combined with lateral recess block in preemptive analgesia in elderly patients undergoing the orthopedics operation of lower limb.Methods60 elderly patients scheduled for lower extremity orthopedic surgery from Janurary to December 2016 in our hospital were selected and they were divided into group A,B and C by random number table,and there were 20 cases in each group.Group A was given Flurbiprofen Axetil combined with lateral recess block for preemptive analgesia.Group B was given lateral recessive obstruction and postoperative continuous lateral recess analgesia.Group C was given simple continuous epidural block.The success rate of puncture for lateral recessive obstruction and continuous epidural block,and puncture time, postoperative VAS pain score,hospital stay and hospitalization cost and so on were observed.ResultsThe VAS score of group A were significantly lower than those of group B and group C at 1,4,16,24,48 h after operation(P<0.05).The VAS score of group B was lower than that of group C,but the difference was not statistically (P>0.05).The success rate of group A was 95.0%,which was significantly higher than that of group B and group C(85.0%and 80.0%),and the time of puncture was shorter than that of group B and C,the difference was statistically significant(P<0.05).The time of hospitalization and hospitalization in group A were significantly shorter than those in group B and group C,the difference was statistically significant(P<0.05).ConclusionThe clinical application of Flurbiprofen Axetil combined with lateral recessive obstruction in elderly patients with orthopedic surgery is simple,safe and effective.The success rate of puncture is high and the complication is less.
2017 Vol. 24 (14): 100-102 [Abstract] ( 118 ) HTML (36 KB)  PDF  (0 KB)  ( 39 )
103 Influence of Remifentanil and Propofol for total intravenous anesthesia on cognitive function in elderly patients undergoing laparoscopic cholecystectomy
XU Jian-li
ObjectiveTo explore the influence of Remifentanil and Propofol for total intravenous anesthesia on cognitive function in elderly patients undergoing laparoscopic cholecystectomy.Methods84 elderly patients given laparoscopic cholecystectomy in our hospital from June 2015 to December 2016 were selected and randomly divided into two groups, and there were 42 cases in each group.The control group was given Sevoflurane for balance anesthesia,while the experimental group was given Remifentanil and Propofol for total intravenous anesthesia.The anesthetic effect and its influence on cognitive function of the two groups were observed.ResultsAfter operation,the operation time,extubation time between two groups had no statistical difference (P>0.05),while the recovery time,spontaneous breathing and the recovery time of directive force in the experimental group were significantly shorter than those of the control group(P<0.05). In addition to there was no statistical difference(P>0.05)of conscious state 24 hours after extubation,then at other time slot,the conscious state in the experimental group were significantly better than those of the control group (P<0.05).In addition there was no significant difference (P>0.05)between the cognitive function of two groups of patients before 24 hours and 24 hours after extubation (P>0.05),and at other time slot,cognitive function in the experimental group were significantly better than those of the control group(P<0.05).ConclusionRemifentanil and Propofol for total intravenous anesthesia applied in elderly patients undergoing laparoscopic cholecystectomy can increase the stable degree of vital signs during operation and effectively reduce the stress of patients,and can achieve significant effect on the recovery of cognitive function,and it is worthy of clinical wide promotion.
2017 Vol. 24 (14): 103-105 [Abstract] ( 131 ) HTML (34 KB)  PDF  (0 KB)  ( 41 )
106 Effect of commonly used western medicine combined with traditional Chinese medicine in the treatment of chronic pelvic inflammatory disease in department of gynecology and obstetrics
ZHANG Zhong-yang
ObjectiveTo investigate the effect of commonly used drugs in the treatment of chronic pelvic inflammatory disease in department of gynecology and obstetrics.Methods168 cases of patients with chronic pelvic inflammatory disease in our hospital from January to December in 2016 were selected and divided into the treatment group and the contrast group according to the medical record number,with 84 cases in each group.The treatment group was treated with western medicine combined with Kangfu Xiaoyan Suppository,Fukeqianjin Tablets and traditional Chinese medicine decoction,while the contrast group was treated with routine western medicine.The symptom scores,the levels of serum tumor necrosis factor before and after treatment and therapeutic effects were compared between the two groups.ResultsThe clinical symptom score of the treatment group was significantly lower than that of the contrast group,with significant difference (P<0.05).The total effective rate of the treatment group was 96.43%,which was higher than 83.33%of the contrast group,with significant difference (P<0.05).The level of serum tumor necrosis factor in the treatment group was lower than that in the contrast group,with significant difference (P<0.05).ConclusionTreatment of chronic pelvic inflammatory disease with traditional Chinese medicine can improve the treatment effect and improve the symptoms of patients,and is worthy of clinical promotion and application.
2017 Vol. 24 (14): 106-108 [Abstract] ( 122 ) HTML (32 KB)  PDF  (0 KB)  ( 47 )
109 Clinical effect of Sucralfate Tablets combined with Bifidobacterium Triple Viable Capsule in the treatment of diarrhea type irritable bowel syndrome
XIE Jun-feng ;HU Yun-shu
ObjectiveTo explore the clinical effect of Sucralfate Tablets combined with Bifidobacterium Triple Viable Capsule in the treatment of diarrhea type irritable bowel syndrome.Methods220 patients with diarrhea type irritable bowel syndrome who were treated in our hospital from February 2011 to February 2016 were selected and randomly divided into the experimental group and the control group,110 cases in each group.The control group was treated with Bifidobacterium Triple Viable Capsule,the experimental group was treated with Sucralfate Tablets on the basis of the control group.The two groups were treated for 6 cycles,and after 4 weeks of withdrawal,the clinical efficacy of the two groups was observed.ResultsThe total effective rate of the experiment group was 92.73%,which was higher than 80.91%of the control group,with significant difference (P<0.05).The abnormal clinical symptoms after treatment in the experimental group were significantly relieved,compared with the control group,the difference was statistically significant(P<0.05).There was no significant difference in the incidence rate of adverse reactions between the two groups(P>0.05).The recurrence rate at 1 months and 2 months of the experimental group was 0.91%and 4.55%,which was significantly lower than that of the control group(5.45%and 12.73%),with significant difference(P<0.05).ConclusionSucralfate Tablets combined with Bifidobacterium Triple Viable Capsule in the treatment of diarrhea type irritable bowel syndrome is safe and effective,the clinical symptoms of the patients can be significantly improved,and the adverse reactions is less,and it is worthy of clinical promotion and application.
2017 Vol. 24 (14): 109-111 [Abstract] ( 143 ) HTML (33 KB)  PDF  (0 KB)  ( 37 )
112 Efficacy and safety analysis of Clozapine combined with Amisulpride in the treatment of refractory schizophrenia
ZENG Hui-ying; SONG Dan-xing ;WU Zhong-jian
ObjectiveTo explore the efficacy and safety of Clozapine combined with Amisulpride in the treatment of refractory schizophrenia.Methods80 patients with refractory schizophrenia admitted in our hospital from June 2015 to June 2016 were selected and divided into the control group and the observation group according to the random number table method,40 cases in each group.The control group was treated with Clozapine,the observation group was treated with Clozapine combined with Amisulpride.The PANSS and TESS were used to evaluate the clinical efficacy and adverse drug reactions of the two groups after 12 weeks of the treatment.ResultsThe total effective rate after treatment of the observation group was 80.0%,which was significantly higher than that of the control group (62.5%),with significant difference (P<0.05).The total score of PANSS,the negative and positive symptom scores after treatment in the observation group was significantly lower than that in the control group,with significant difference (P<0.05).There was no significant difference in the incidence rate of adverse reactions between the two groups(P>0.05).ConclusionThe curative effect of Clozapine combined with Amisulpride in the treatment of refractory schizophrenia is significant,it is safe with less adverse reaction.
2017 Vol. 24 (14): 112-114 [Abstract] ( 191 ) HTML (33 KB)  PDF  (0 KB)  ( 39 )
115 Clinical effect of Clarithromycin and Azithromycin in the treatment of Mycoplasma pneumonia in children and its influence on the scores of symptoms and signs
YE Xu-fang
ObjectiveTo explore the clinical effect of Clarithromycin and Azithromycin in the treatment of Mycoplasma pneumonia in children and its influence on the scores of symptoms and signs.MethodsFrom February 2015 to December 2016,110 cases of Mycoplasma pneumonia in our hospital were selected as the research object,and divided into the control group and the combined group according to different treatment methods,55 cases in each group.The control group was given Azithromycin treatment,the combined group was given Azithromycin and Clarithromycin combined treatment.The clinical efficacy,symptom and sign score,clinical symptom disappearance time and the incidence rate of adverse reaction were compared between the two groups.ResultsThe total effective rate of the combined group was 96.36%,which was higher than 80.00%of the control group,with significant difference (P<0.05).The scores of fever, cough,pulmonary rale and dyspnea in the combined group was lower than that in the control group,with significant difference(P<0.05).The disappearance time of fever,cough,pulmonary rale and dyspnea in the combined group was shorter than that in the control group,with significant difference (P<0.05).The incidence rate of adverse reactions in the combined group was 5.45%,which was lower than 20.00%in the control group,with significant difference(P<0.05).ConclusionThe clinical effect of Azithromycin combined with Clarithromycin in the treatment of children with Mycoplasma pneumonia is better.It can significantly improve the clinical symptoms of patients and reduce the incidence of adverse reactions.It is worthy of clinical promotion and application.
2017 Vol. 24 (14): 115-117转121 [Abstract] ( 149 ) HTML (38 KB)  PDF  (0 KB)  ( 44 )
118 Effect observation of Telbivudine in the treatment of child-bearing period male patients with chronic hepatitis B
Song Hui ping
ObjectiveTo investigate the effect and adverse reaction of Telbivudine in the treatment of child-bearing period male patients with chronic hepatitis B.Methods68 cases of chronic hepatitis B from January to December in 2013 in our hospital were selected and divided into the treatment group(36 cases)and the control group(32 cases)according to different treatment methods.The treatment group was given Telbivudine therapy on the basis of liver protection and enzyme reduction,the control group was given only liver protection and enzyme reduction.The effect of the two groups was compared.ResultsThe level of HBV-DNA in the treatment group at 12,24 and 48 weeks was lower than that in the control group,with significant difference(P<0.01).There was no significant difference in the ALT recover normal rate between the two groups at 4 and 8 weeks(P>0.05).The recovery normal rate of ALT in the treatment group at 12 and 24 weeks was higher than that in the control group,with significant difference(P<0.05).There was no significant difference in the HBsAg positive rate of the two groups at birth,6 months after birth and 12 months after birth (P>0.05). There were 2 cases with elevated creatine kinase in the treatment group,all of which were elevated below grade 2,and there was 1 case of dizziness and nausea at first weeks of treatment.ConclusionTelbivudine has antiviral effect with relatively high efficiency,with less adverse reaction,it is safe for male of childbearing age.
2017 Vol. 24 (14): 118-121 [Abstract] ( 120 ) HTML (40 KB)  PDF  (0 KB)  ( 45 )
122 Effect comparison of Amlodipine Besylate combined with Chaihu plusing Longgu Oyster Decoction or Flupentixol and Melitracen treating primary hypertension complicated with anxiety
HUANG Wei-ming
ObjectiveTo compare the effect of Amlodipine Besylate combined with Chaihu plusing Longgu Oyster Decoction or Flupentixol and Melitracen treating primary hypertension complicated with anxiety.Methods196 patients with primary hypertension complicated with anxiety diagnosed and treated in our department from January 2015 to December 2016 were selected and they were divided into Chaihu plusing Longgu Oyster Decoction group and Flupentixol and Melitracen Tablets group.Two groups were given Amlodipine Besylate,while Chaihu plusing Longgu Oyster Decoction group was added Chaihu plusing Longgu Oyster Decoction,and Melitracen Tablets group was added Flupentixol and Melitracen Tablets.The level of blood pressure and anxiety and depression score of two groups were compared before and after treatment.ResultsCompared with before treatment,the systolic blood pressure,diastolic blood pressure,SAS score and SDS score of the two groups were decreased,the difference was statistically significant(P<0.05).After treatment,the difference between the two groups was statistically significant about the above-mentioned indexes (P<0.05).ConclusionAmlodipine Besylate combined with Chaihu plusing Longgu Oyster Decoction or Flupentixol and Melitracen treating primary hypertension complicated with anxiety.
2017 Vol. 24 (14): 122-124 [Abstract] ( 139 ) HTML (31 KB)  PDF  (0 KB)  ( 39 )
125 Analysis the clinical effect and safety of Sanren Decoction adding and subtracting for adjuvant treatment of western medicine treating chronic heart failure caused by coronary heart disease
HE Mu-long
ObjectiveTo explore the clinical effect and safety of Sanren Decoction adding and subtracting for adjuvant treatment of western medicine treating chronic heart failure caused by coronary heart disease.Methods68 inhospital patients who diagnosed as chronic heart failure caused by coronary heart disease treated in our hospital from January 2015 to December 2016 were randomly selected.Patients were divided into observation group and control group by random number table method,and each group was 34 cases.The control group was used basic treatment of western medicine,and the observation group was used basic treatment of western medicine combined with Sanren Decoction adding and subtracting.Before and after treatment,the change of walking distance of 6-MWT,LVEF and LVESD were observed in two groups.After treatment,the treatment effect between two groups were compared.ResultsThe total effective rate in observation group and control group were respectively 94.11%and 70.60%,and the difference was significant(P<0.05).After treatment,compared with the control group,the walking distance of the 6 min walking test increased,LVEF increased,and the LVESD decreased (P<0.05).ConclusionSanren Decoction adding and subtracting for adjuvant treatment of western medicine treating chronic heart failure caused by coronary heart disease has good clinical effect and safety.
2017 Vol. 24 (14): 125-127 [Abstract] ( 141 ) HTML (32 KB)  PDF  (0 KB)  ( 33 )
128 The status of community home care model,and its role and impact on management of chronic diseases in the elderly
ZHU Fei-ying; PAN Gui-xing ;MIN Ya-ting; WANG Xiao ;GONG Zhi-wu ;ZHONG Qing-ling
ObjectiveTo study the status of community home care model,and its role and impact on management of chronic diseases in the elderly.MethodsFrom July 2016 to December 2016,some of the communities were selected from party of Jiangxi,Ningxia,Shanghai,Guizhou,Xinjiang and other cities.The questionnaire was used to investigate the health status of the elderly,current situation of community home care model and management of chronic diseases.ResultsThe prevalence rate of chronic diseases was high in elderly patients,cardiovascular and cerebrovascular diseases(68.1%),diabetes mellitus(40.3%),and osteoporosis(28.7%)were the highest incidence of the three major diseases in the elderly population.Community home care model was common in China,which provides physical examination, health counseling,intravenous fluids,medical treatment and other services for the elderly.There are still some problems such as single service mode,insufficient health resources.However,this service could enhance the elderly′s awareness of chronic diseases,delayed the development of the disease and reduced the cost of medical treatment.ConclusionThe health status of the elderly is not satisfactory,and the prevalence of chronic diseases is high.Although there are some deficiencies in the model of community home care,it provides a number of services for the management,prevention and treatment of chronic diseases in the elderly has a positive significance,which can reduce the cost of care,improve the quality of life of the elderly.
2017 Vol. 24 (14): 128-130转137 [Abstract] ( 126 ) HTML (38 KB)  PDF  (0 KB)  ( 45 )
131 Application effect of PDCA cycle in the pharmacy intravenous admixture services
YANG Jin-yuan; GAN Mei-chan ;LIANG Guang-bin ;LU Jian-chun
ObjectiveTo understand the satisfaction degree of the pharmacy intravenous admixture services(PIVAS), and to explore the feasibility of PDCA cycle in optimizing the workflow of PIVAS.MethodsThe satisfaction questionnaire was designed for the PDCA activities from July 2015 to June 2016,and the satisfaction survey was conducted in the second half of 2016 on the doctors,the nurses and the patients.The survey results were summarized and analyzed, and compared with the satisfaction survey data of clinical department and satisfaction survey data of patient in 2015.ResultsThe overall satisfaction rate was 97.92%in the clinical department,compared with 2015 increased by 14.92%, and the overall satisfaction rate of patients was 83.83%,compared with 2015 increased by 1.33%.ConclusionPDCA cycle is benefited to improve the workflow of the PIVAS continuously,which can improve the satisfaction of clinical departments and patient,and will contribute to assist the daily work of clinical.
2017 Vol. 24 (14): 131-133 [Abstract] ( 138 ) HTML (33 KB)  PDF  (0 KB)  ( 32 )
134 Investigation on mental health status and its influencing factors among medical staff of Bureau of Prison in Jiangxi Province
LUO Xuan;YUAN Zhao-kang;TU Hui
ObjectiveTo observe the mental health status of medical staff of Bureau of Prison in Jiangxi Province and analyze the influencing factors,and to develop targeted psychological counseling strategies to improve their psychological health.Methods350 medical staff of Bureau of Prison in Jiangxi Province from July to October in 2016 were enrolled to investigate,and the mental health status were surveyed by the self-assessment lists of symptom scale(SCL-90) and Campbell happiness index,then the single factor descriptive analysis and multi-factor Logistic regression analysis were carried out to determine the influencing factors among medical staff of Bureau of Prison in Jiangxi Province.The targeted psychological counseling strategies according to the results of the analysis were formulated.ResultsThe recovery rate was 90.86%in 350 subjects,among which there were 155 cases with mental health problems.The univariate analysis showed that the male,wrinkly,married,undergraduate education,clinical prison medical workers had more psychological problems.Multivariate analysis showed that both of gender,standard of culture,marital status,age,length of service were the mental health factors that affected the psychological problems of the prison medical staff.ConclusionThe mental health status of medical staff of Bureau of Prison in Jiangxi Province is not ideal,and there are many influencing factors,so psychological counseling should be targeted to improve their mental health status.
2017 Vol. 24 (14): 134-137 [Abstract] ( 114 ) HTML (36 KB)  PDF  (0 KB)  ( 47 )
138 Early warning effect of clinical nutrition index on pressure ulcer in patients with ICU
HUO Wan-jun;LIU Rong-min;XIONG Xiao-ling
ObjectiveTo explore the relationship between pressure ulcers and common clinical nutritional indexes in ICU patients.Methods256 hospitalized patients in ICU of a three class A hospital in Guangdong Province from May 2016 to February 2017 were investigated by using self-designed questionnaire for risk factors of decubitus ulcers in ICU patients.ResultsUnivariate analysis showed that there were significant differences in hemoglobin,red blood cell, hematocrit,albumin,total protein,mid-upper arm circumference,calf circumference and body mass index between two groups(P<0.05).Logistic regression analysis showed that,the decrease of albumin level and calf circumference were independent risk factors for pressure ulcer in ICU patients.ConclusionThe medical staff should pay attention to the early warning effect of the decrease of albumin level and calf circumference on pressure ulcers.
2017 Vol. 24 (14): 138-140 [Abstract] ( 129 ) HTML (35 KB)  PDF  (0 KB)  ( 40 )
141 The application of PDCA mode in 5S management of three rooms
XU Hua ;MA Xin-cui;MA Xiu-hua; TIAN Kun
ObjectiveTo explore the application effect of PDCA mode in 5S management of three rooms.MethodsBefore management,from June 2016 to August,the goods standardized management of the three rooms (therapeutic room, treatment room,nurse′s Office)in the 23 wards of our hospital were selected as the control group.After management,from September 2016 to November,23 wards taken 5S management of our hospital were selected as the observation group. The 5S management was promoted by using PDCA mode.The effect before and after 5S management was compared by calculating the meetting requirements ward compliance rate of three rooms standard management.ResultsThe reduced rate of base drugs,rescue drugs and specialty drugs in the observation group were respectively 42.1%,9.09%and 62.5%.Compared with the control group,the type of medicine in the wards of observation group decreased significantly, with significant difference (P<0.05).The meetting requirements ward compliance rate of three rooms management in the observation group was 91.3%,which was higher than that in the control group (67.4%),with significant difference (P<0.05).ConclusionThe application of PDCA mode in the management of three rooms 5S has good effect,which can effectively improve the management of the three room articles and the quantitative and positioning of drugs,not only improves the room environment,but also improves the quality of nursing staff.
2017 Vol. 24 (14): 141-143 [Abstract] ( 150 ) HTML (34 KB)  PDF  (0 KB)  ( 44 )
144 Discipline evolution of urinology from the perspective of scientific management
WANG Xu-kun;CHEN Shi-jing
Since the early 1980s,the urinology has been developing steadily in China.A number of books were published using the urinology and its branches as the keywords of their titles.This article categorizes the urinology′s branch disciplines built and being built into seven discipline sub-groups,and tries to construct the discipline structure of urinology.Then a countermeasures is proposed that will promote the orderly evolution of the urinology discipline in the near future.
2017 Vol. 24 (14): 144-148 [Abstract] ( 146 ) HTML (49 KB)  PDF  (0 KB)  ( 47 )
149 Evaluation on the effect of nursing professional management in improvement of nursing quality in operation room
DENG Rui
ObjectiveTo explore the effect of nursing professional management in nursing quality in the operation room.MethodsThe operation rooms and nurses in our hospital from January 2015 to January 2016 were selected as the object of this research and were divided into 6 major groups in accordance with the characteristics of operation rooms and disease department.At the mean while,in combination of the number of operations in each group and the degree of difficulty,all the nurses were re-allocated to achieve the purpose of detailed division of labor with in the professional division,which formed a specialized surgical nurse management model.The patients and doctors′satisfaction as well as nurses′self-evaluation before and after implementation of specialized management were observed.ResultsAfter implementation of professional management,the certain proportion in nurses′self-evaluation content was increased in comparison with post-implementation,with statistically significant difference (P<0.05);the post-implementation patients and doctors′nursing satisfaction was significantly higher than pre-implementation one,with statistically significant difference(P<0.05).ConclusionApplication of the professional management mode in the operation room achieves significant effect,which is conducive to the nurses′self-evaluation,theoretical knowledge and professional skills in the operation room;at the same time,it can promote the patients and doctors′high evaluation of nursing work so as to successfully improvethe overall level of nursing quality,which is worthy of popularization and application.
2017 Vol. 24 (14): 149-151 [Abstract] ( 125 ) HTML (31 KB)  PDF  (0 KB)  ( 38 )
152 PDCA cycle management model was applied to prevent fall in the patients with digestive internal medicine discharge correlation effect of management
ZHU Yu-lan;CHEN Shu-qin;LUO Zhi-ling
ObjectiveTo study the application of PDCA cycle management model in prevention of patients with digestive internal medicine discharge correlation fall nursing effect.Methods100 patients were selected,and had been hospitalized in our hospital digestive internal medicine from October 2015 to October 2016.They were randomly divided into control group and experimental group,50 cases in each group.Two groups of patients were given routine nursing care of digestive diseases.In addition,the experimental group patients were given the PDCA cycle management;the incidence rate of two groups of patients were compared the stumble.According to stumble,this paper was analyzed the reasons of events,surveyed of general nursing staff to prevent falls within relevant knowledge,through analysis,the summary,find the cause of the fall in the correlation evacuation and influencing factors,and formulate relevant measures, and inspection,analysis and improvement.ResultsPDCA circulation department paramedics were found after the application in the knowledge level about preventing falls significantly promoted,the difference was statistically significant (P<0.05);patient discharge correlation significantly was lower incidence of falls,the difference was statistically significant(P<0.05);satisfaction of patients to nursing improved obviously,the difference was statistically significant(P<0.05).ConclusionPDCA cycle management model,after the application can improve the patient and family nursing staff knowledge of fall prevention,reduce the incidence rate of discharge correlation stumble,improve nursing satisfaction.
2017 Vol. 24 (14): 152-154 [Abstract] ( 150 ) HTML (32 KB)  PDF  (0 KB)  ( 39 )
155 Efficacy of nursing intervention on prethrombotic state in gynecologic laparoscopic surgery
PAN Jia-jia ;CHEN Zhi-lin
ObjectiveTo explore the efficacy of nursing intervention on prethrombotic state in gynecologic laparoscopic surgery.Methods600 gynecological patients underwent laparoscopic surgery from January 10th2014 to December 10th2015 were selected and randomly divided into the observation group and the control group,with 300 cases in each group.Patients in the observation group were given preventive nursing intervention,while patients in the control group were given routine nursing.The PT,APTT,the level of FIB,the incidence of pain,the time of intestinal exhaust and activity time were compared between two groups.ResultsAfter nursing,the PT[(9.45±0.36)s]and APTT[(23.04±2.36)s]in the observation group were shorter than those in the control group[(11.02±0.52),(25.74±2.51)s],the level of FIB[(5.48±1.45)g/L] was higher than thai in the control group[(3.58±1.03)g/L],the incidence of pain(1.67%)was lower than that in the control group(24.67%),the time of intestinal exhaust[(2.36±0.45)d]and activity time[(1.03±0.06)d]were shorter than those in the control group[(4.85±1.05),(3.14±0.98)d],and all the differences were statistically significant(P<0.05).ConclusionThe efficacy of nursing intervention on prethrombotic state in gynecologic laparoscopic surgery is definite.It can shorten the PT and PTT and can improve the level of FIB of patients,also can relieve pain and promote patients recover.
2017 Vol. 24 (14): 155-157 [Abstract] ( 108 ) HTML (33 KB)  PDF  (0 KB)  ( 35 )
158 Efficacy observation of compound salvia injection wet dressing in newborns with infusion extravasation
MAI Hui-qiong
ObjectiveTo explore the efficacy observation of compound salvia injection wet dressing in newborns with infusion extravasation.Methods82 cases of neonatal patients with infusion extravasation from March 2015 to March 2016 in our hospital were selected and randomly divided into the observation group (42 cases)and the control group (40 cases).Patients in the control group were given wet dressing with 50%magnesium sulfate solution;while the observation group were given wet dressing with compound salvia injection.The time of swelling disappear,treatment effect and the incidence of adverse reaction were compared between two groups.ResultsThe beginning swelling disappear time, markedly effective time and totally swelling disappear time in the observation group were shorter than those in the contrl group;the total effective rate(97.62%)was higher than that in the control group(75.00%),the differences were statistically significant(P<0.01).During treatment,there was no adverse reaction in the observation group,while the incidence of adverse reaction in the control group was 10.0%,the difference was statistically significant(P<0.05).ConclusionThe treatment effect of compound salvia injection wet dressing in treating newborn infusion extravasation is better than 50% magnesium sulfate solution wet dressing,which with short onset time,no obvious adverse reactions and suitable for clinical application.
2017 Vol. 24 (14): 158-160 [Abstract] ( 103 ) HTML (34 KB)  PDF  (0 KB)  ( 39 )
161 Nursing observation of postoperative recovery period of general anesthesia for cesarean section in obesity puerpera
FU Yi
ObjectiveTo explore nursing observation of postoperative recovery period of general anesthesia for cesarean section in obesity puerpera.Methods66 obesity puerperas who underwent cesarean section in our hospital from June 2013 to May 2015 were selected and divided into the observation group and the control group according to random number table,with 33 cases in each group.Puerperas in the observation group were given targeted nursing intervention according to the puerperas′characteristics during postoperative recovery period;while puerperas in the control groupwas were given traditional nursing intervention.The levels of blood pressure,heart rate,the incidence of dysphoria and recover condition after general anesthesia were compared between two groups.ResultsThe levels of blood pressure and heart rate of puerperas and the incidence of dysphoria in the observation group were lower than those in the control group,the time of eye opening,making a fist after calling,autonomous respiration and tube drawing in the observation group were shorter than that in the control group,and all the differences were statistically significant(P<0.05).ConclusionApplication of targeted clinical nursing for obesity puerperas during post-operative recovery period who underwent cesarean section under general anesthesiafor maternal obesity can effectively control the incidence of dysphoria during the recovery period and quickly stabilize the puerperas′life index.Moreover,comprehensive nursing intervention model can also effectively reduce the puerperas′recovery time and regain puerperas′consciousness in a fast manner,which has a positive impact on the subsequent treatment.
2017 Vol. 24 (14): 161-163 [Abstract] ( 127 ) HTML (33 KB)  PDF  (0 KB)  ( 35 )
164 Application of mind mapping in the nursing of complication in patients with cerebral apoplexy in acute phase
YAN Guo-hui
ObjectiveTo application of mind mapping in the nursing of complication in patients with cerebral apoplexy in acute phase.Methods48 nurses worked in the department of neurology in our hospital from March 2013 to March 2016 were selected and randomly divided into two groups,with 24 cases in each group.The nurses in the control group were trained without mind mapping,while the nurses in the experiment group were trained with mind mapping,nurses in two group gave patients specialist nursing and health education.120 patients with cerebral apoplexy in acute phase admitted into our hospital at the same were selected and were given specialist nursing and health education by nurses in two groups,60 cases in each group.The incidence of complications of patients,the cognitive level and nursing ability of complications were compared between two group.ResultsThe incidence of complications of patients in the experiment group(25.00%)was lower than that in the control group(10.00%),and the difference was statistically significant(P< 0.05).Before training,there were no significantly different among the scores of cognitive level and nursing ability of complications in two groups(P>0.05);after training,the scores of two indexes in the experiment group[(91.35±6.13),(92.43± 6.85)points]were higher than those in the control group[(64.68±5.18),(66.52±5.42)points],and the differences were statistically significant(P<0.05).ConclusionMind mapping in nursing of cerebral apoplexy in acute phase with complications has significant application value,it can obviously improve the cognitive level and nursing ability of nurses to cerebral apoplexy with complications,and decrease the incidence of complications.
2017 Vol. 24 (14): 164-166 [Abstract] ( 133 ) HTML (33 KB)  PDF  (0 KB)  ( 38 )
167 Efficacy of psychological hypnotic implication on the anesthesia with small and medium dose Ropivacaine in cesarean section
XU Guo-cheng;CHEN Yan;YANG Qing-geng
ObjectiveTo explore the efficacy of psychological hypnotic implication on the anesthesia with small and medium dose Ropivacaine in cesarean section.Methods70 cases of cesarean section patients with scar uterus characteristics in our hospital from August 2015 to December 2016 were selected and randomly divided into the control group and the observation group,with 35 cases in each group.Patients in the control group were given topical anesthesia with 1%Ropivacaine 1.0 ml(10 mg),while patients in the observation group were given hypnosis on the basis of the control group.The pain degree,the onset time of sensory and motion,time of postoperative analgesia and neonatal Apgar scores were compared between two groups.ResultsThe VAS scores at 10 min,30 min on intraoperation and 10 min,1 h,24 h on postoperation in the observation group were lower than those in the control group;the onset time of sensory and motion in the observation group were shorter than those in the control group,time of postoperative analgesia was longer than that in the control group,and the differences were statistically significant(P<0.05).There were no significant difference on neonatal Apgar scores between two groups(P>0.05).ConclusionThe anesthesia effectiveness which combines the ropivacaine with hypnosis is well-tried in the patients with cesarean section scar uterus characteristics,which effectively reduce postoperative pain and psychological discomfort.
2017 Vol. 24 (14): 167-169 [Abstract] ( 123 ) HTML (33 KB)  PDF  (0 KB)  ( 41 )
170 Efficacy of hospital-community self-management education model on patients with diabetes mellitus
LIN Hui-qing; CHEN Xiao-zheng; HE Jian-min ;CHEN Xiang-hua
ObjectiveTo explore the efficacy of hospital-community self-management education model on patients with diabetes mellitus.Methods120 patients with diabetes mellitus in our hospital from September 2015 and September 2016 were selected and randomly divided into the observation group and the control group.Patients in the control group were given traditional education mode,while patients in the observation group were given hospital-community self-management education model.The levels of metabolic indexes,quality of life and cognition degree of diabetes knowledge were compared between two groups.ResultsBefore intervention,there were no significantly different among the levels of random blood glucose,total cholesterol,high-density lipoprotein cholesterol and glycosylated hemoglobin in two groups (P>0.05);after intervention,the levels of those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The scores of all indexes in quality of life and cognition degree of diabetes knowledge in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).ConclusionThe hospital-community self-management education pattern in patients with diabetes is effective,and it is worthy of clinical application.
2017 Vol. 24 (14): 170-172 [Abstract] ( 111 ) HTML (34 KB)  PDF  (0 KB)  ( 38 )
173 Efficacy of comprehensive intervention of hand hygiene on nosocomial infection in patients in department of oncology
ZHONG Hong-ying
ObjectiveTo explore the efficacy of comprehensive intervention of hand hygiene on nosocomial infection in patients in department of oncology.Methods200 patients with oncology from January 2015 to December 2016 in our hospital were selected and divided into the observation group and the control group according to the random number table method,with 100 cases in each group.The control group were given routine clinical nursing,while the observation group were given the comprehensive intervention of hand hygiene.The rate of hospital infection,the rate of hand hygiene,the qualified rate of hand microbiological examination,the qualified rate of hand disinfection,the time of hospital stay,the antibiotic expenses,the anxiety status and the quality of life were compared between two group.ResultsThe rate of hospital infection in the observation group were lower than that in the control group;the rate of hand hygiene,the qualified rate of hand microbiological examination,the qualified rate of hand disinfection were higher than those in the control group,the time of hospital stay was shorter than that in the control group,the antibiotic expenses were less than that in the control group,the level of anxiety was lower than that in the control group,the quality of life was higher than that in the control group,and all the differences were statistically significant(P<0.05).ConclusionThe comprehensive intervention of hand hygiene has great influence on nosocomial infection in patients with oncology,which can effectively improve the hygienic performance of hand hygiene,and check the qualified condition of hand and microbiological examination,reduce the incidence of nosocomial infection,and keep the patients′good mental state and high the quality of life,and can shorten the hospital stay,reduce medical expenses.It is worthy of clinical promotion.
2017 Vol. 24 (14): 173-175 [Abstract] ( 123 ) HTML (31 KB)  PDF  (0 KB)  ( 32 )
176 Application efficacy of humanistic care in nursing of malignant tumor
ZOU Yu-fen;FENG Ling
ObjectiveTo explore the application efficacy of humanistic care in nursing of malignant tumor.Methods120 cases of patients with malignant tumor who hospitalized in the First Affiliated Hospital of Gannan Medical College from January 2015 to December 2016 were selected as the subjects and randomly divided into the obsevation group and the control group,with 60 cases in each group.The control group was given conventional nursing plan,while the observation group was given humanistic care on the basis of the control group.The levels of anxiety and depression,quality of life and the degree of nursing satisfaction were compared between two groups.ResultsBefore nursing,there were no significantly different between the scores of SAS and SDS in two groups(P>0.05);after nursing,the scores of SAS and SDS in the observation group were lower than those in the control group,and the differences were statistically significant(P< 0.05).After nursing,the physical function,pain and discomfort,mental state and behavior state in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.01).The degree of total, service attitude and technical satisfaction in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).ConclusionThe application of humanistic care in patients with malignant tumor not only can improve the negative emotions and the quality of life of patients,but also to improve the level of care services from all aspects.
2017 Vol. 24 (14): 176-178 [Abstract] ( 108 ) HTML (34 KB)  PDF  (0 KB)  ( 43 )
179 Efficacy of flexible management in clinical nursing management in Department of Gynecology and Obstetrics
YU Long-ying
ObjectiveTo explore the efficacy of flexible management in clinical nursing management in Department of Gynecology and Obstetrics.Methods280 puerperas in the Department of Gynecology and Obstetrics in our hospital from Jaunuary 2015 to January 2016 were selected and divided into the observation group(n=140)and the control group (n=140)according to the different treatment time.The control group was implemented routine nursing management,while the experimental group was implemented flexible management.The incidence of adverse event,nursing error and complaint,nursing quality and satisfaction were compared between two groups.ResultsThe incidence of adverse event,nursing error and complaint in the observation group(2.86%,0.71%,0.00%)were lower than those in the control group(13.57%, 5.00%,2.86%);the nursing quality[(92.4±6.1),(9.4±0.5)points]and satisfaction were higher than those in the control group [(84.1±2.1),(6.4±0.6)points],and the differences were statistically significant(P<0.05).ConclusionThe application of flexible management in the nursing management of Department of Obstetrics and Gynecology can reduce the incidence of infection,dystocia,neonatal asphyxia and nursing error and complaint and can improve the nursing quality and satisfaction.
2017 Vol. 24 (14): 179-181 [Abstract] ( 130 ) HTML (32 KB)  PDF  (0 KB)  ( 32 )
182 Application of continuous nursing in patients after operation with hypertensive cerebral hemorrhage
LAI Pin-ying; GU Yan; LI Yan-qun; LIANG Yan-qiong
ObjectiveTo explore the application of continuous nursing in patients after operation with hypertensive cerebral hemorrhage.Methods90 cases of patients diagnosed with hypertensive cerebral hemorrhage in our hospital from January 2014 to January 2016 were selected and randomly divided into the observation group and the control group,with 45 cases in each group.All the patients were given the same treatment method in hospital,the observation group were given continuous nursing intervention,while the control group were given no nursing intervention.The health behavior,the blood pressure,the rate of rebleeding were compared between two groups.ResultsThe scores of all indexes of health behavior in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).Before nursing,there were no significantly different among the levels of blood pressure(systolic and diastolic pressure),the score of MBI in two groups(P>0.05);after nursing,the levels of blood pressure in the observation group were lower than those in the control group,the score of MBI in the observation was higher than that in the control group,and the differences were statistically significant(P<0.05).The rate of rebleeding in the observation was lower than that in the control group,and the difference was statistically significant(P<0.05).ConclusionThe application of continuous nursing care to patients with hypertensive cerebral hemorrhage,help patients to establish good health behavior after discharge,more help to control blood pressure,reduce the occurrence of bleeding time,it is worth promoting.
2017 Vol. 24 (14): 182-184 [Abstract] ( 118 ) HTML (31 KB)  PDF  (0 KB)  ( 23 )
185 Efficacy of family centered maternity care in prevention of puerperal maternal postpartum depression
CHEN Lan-fang
ObjectiveTo explore efficacy of family centered maternity care in prevention of puerperal maternal postpartum depression.Methods150 puerperas received:natural childbirth in our hospital from October 2015 to October 2016 were selected and randomly divided into the control group and the experiment group,with 75 cases in each group.The control was given routine nursing,while the experiment group was geiven family centered maternity care on the basis of the contrl group.The depression and anxiety degree and the incidence of depression were compared between two groups.ResultsBefore nursing,there were no significantly different among the scores of EPDS and SAS in two groups(P>0.05); after nursing,the scores of EPDS and SAS in two groups were all decreased,and compared with those before nursing,the differences were statistically significant(P<0.05).And those in the experiment group were lower than those in the control group,and the differences were statistically significant(P<0.05).ConclusionNatural childbirth maternal depression using a family-centered obstetric care can significantly control and improvement,reduce maternal heart pressure,to improve women's quality of life.Make the lying-in woman and puerperium mood to relax,feel the warmth of family and care,for applying this maternal care is of great significance,is worth for clinical use.
2017 Vol. 24 (14): 185-187 [Abstract] ( 137 ) HTML (30 KB)  PDF  (0 KB)  ( 10 )
188 Observation on the Effect of Humanized Nursing Service Mode in Nursing Care Management of Ophthalmology
WU Li-ying ;ZHOU Ping ;LIANG Dong-hong; ZHU Zhao-hua ;WANG Guang-xiu
ObjectiveTo explore the application effect of humanized nursing service model in ophthalmic outpatient nursing management.Methods132 cases of ophthalmology outpatients were randomly divided into our department from June 2015 to May 2016.The routine group used the routine nursing service mode in the nursing management work.The humanized group applied the humanized nursing service mode in the nursing management work.The scores of nursing management,the quality of care received:,the attitude of nursing staff,the score of operation skills,the score of mission work,the incidence of eye care and nursing,and the change of mental state before and after nursing were compared between the two groups.ResultsThe satisfaction rate of nursing management in the humanized group was higher than that in the conventional group(P<0.05).The score of the quality of the humanized group,the attitude of the nursing staff,the score of the operation skill and the score of the mission were better than those in the conventional group (P<0.05).The incidence of eye care in the group was lower than that in the conventional group (P<0.05).Before treatment,there was no significant difference in psychological anxiety and depression between the two groups(P>0.05);after nursing,the degree of anxiety and depression in the humanized group was significantly lower than that in the conventional group (P< 0.05).ConclusionThe application of humanized nursing service model in the management of ophthalmic outpatient nursing care can be achieved by providing good nursing service,effectively reducing the bad mood of patients,reducing the occurrence of nursing errors and improving patient satisfaction.
2017 Vol. 24 (14): 188-190 [Abstract] ( 140 ) HTML (32 KB)  PDF  (0 KB)  ( 43 )
191 The role of humanistic care in reducing the complications of elderly infusion and improving patient satisfaction
SONG Jie-ru
ObjectiveTo explore the application of humanistic care in reducing the complication of elderly patients with infusion and improving patient satisfaction.MethodsFrom January 2016 to September 2016,hospitalized patients who were treated with infusion in our hospital were randomly divided into control group and experimental group,55 cases in each group.The patients in the control group were treated with routine infusion care.The patients in the experimental group were given humanistic care and nursing care.The intervention time was 1 month.After the intervention,the complications of the infusion were observed by clinical observation and the nursing satisfaction degree was investigated by questionnaire.ResultsThe incidence of adverse reactions such as leakage injury,air embolism,phlebitis and infusion reaction were lower in the experimental group than in the control group (P<0.05).The satisfaction rate of the patients in the experimental group was higher than that those in the control group (P<0.05).ConclusionThe use of humanistic care in elderly infusion patients is conducive to reducing the incidence of complications of infusion,at the same time,to enhance the recognition of patients and their families on nursing services.
2017 Vol. 24 (14): 191-193 [Abstract] ( 126 ) HTML (32 KB)  PDF  (0 KB)  ( 32 )
194 Analysis of application of evidence-based nursing in patients with chronic nephritis
CHEN Xiao-he; GUO Huan-kai;ZHENG Shao-li;LONG Rui-yin ;ZENG Ling-ling
ObjectiveTo study the application effect of evidence-based nursing on patients with chronic nephritis.MethodsAltogether 43 cases of chronic nephritis patients who were treated in our hospital from February to August 2015 were selected as control group and provided with routine treatment and nursing service;another 43 cases of chronic nephritis patients who were treated in our hospital from September 2015 to March 2016 were selected as observation group and provided with evidence-based nursing services on the basis of conventional nursing;the nursing satisfaction, quality of life,24-hour urine protein,BUN,SCr of two groups were evaluated,summarized and compared.ResultsThe satisfaction rate of observation group was 95.35%,was higher than that of control group (65.12%)(P<0.05).The compliance consciousness and behavior score,daily activities,harmonious relationship between family members and psychological emotion of patients in the observation group was(90.08±1.02),(91.45±1.06),(92.30±1.04)and(91.48±1.05)scores respectively,was higher than that of the control group[(75.26±1.40),(76.80±1.02),(74.10±1.01),(73.56±1.07)scores](P<0.05). Before intervention,there was no statistically significant difference in 24-hour urine protein,BUN and SCr betwee two groups(P>0.05);after intervention,24-hour urine protein,BUN and SCr of the observation group was lower than that of the control group(P<0.05).ConclusionProviding clinical nursing service to patients with chronic nephritis,can improve the 24-hour urine protein,BUN and SCr,and with high nursing satisfaction degree and quality of life.
2017 Vol. 24 (14): 194-196 [Abstract] ( 111 ) HTML (34 KB)  PDF  (0 KB)  ( 42 )
Copyright © Editorial Board of 中国当代医药
Supported by:Beijing Magtech