ObjectiveTo explore efficacy of family centered maternity care in prevention of puerperal maternal postpartum depression.Methods150 puerperas received：natural childbirth in our hospital from October 2015 to October 2016 were selected and randomly divided into the control group and the experiment group,with 75 cases in each group.The control was given routine nursing,while the experiment group was geiven family centered maternity care on the basis of the contrl group.The depression and anxiety degree and the incidence of depression were compared between two groups.ResultsBefore nursing,there were no significantly different among the scores of EPDS and SAS in two groups(P>0.05); after nursing,the scores of EPDS and SAS in two groups were all decreased,and compared with those before nursing,the differences were statistically significant(P<0.05).And those in the experiment group were lower than those in the control group,and the differences were statistically significant(P<0.05).ConclusionNatural childbirth maternal depression using a family-centered obstetric care can significantly control and improvement,reduce maternal heart pressure,to improve women's quality of life.Make the lying-in woman and puerperium mood to relax,feel the warmth of family and care,for applying this maternal care is of great significance,is worth for clinical use.