瑞芬太尼和异丙酚全凭静脉麻醉对老年腹腔镜下胆囊切除术后认知功能的影响

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Abstract ObjectiveTo explore the influence of Remifentanil and Propofol for total intravenous anesthesia on cognitive function in elderly patients undergoing laparoscopic cholecystectomy.Methods84 elderly patients given laparoscopic cholecystectomy in our hospital from June 2015 to December 2016 were selected and randomly divided into two groups, and there were 42 cases in each group.The control group was given Sevoflurane for balance anesthesia,while the experimental group was given Remifentanil and Propofol for total intravenous anesthesia.The anesthetic effect and its influence on cognitive function of the two groups were observed.ResultsAfter operation,the operation time,extubation time between two groups had no statistical difference (P>0.05),while the recovery time,spontaneous breathing and the recovery time of directive force in the experimental group were significantly shorter than those of the control group(P<0.05). In addition to there was no statistical difference(P>0.05)of conscious state 24 hours after extubation,then at other time slot,the conscious state in the experimental group were significantly better than those of the control group (P<0.05).In addition there was no significant difference (P>0.05)between the cognitive function of two groups of patients before 24 hours and 24 hours after extubation (P>0.05),and at other time slot,cognitive function in the experimental group were significantly better than those of the control group(P<0.05).ConclusionRemifentanil and Propofol for total intravenous anesthesia applied in elderly patients undergoing laparoscopic cholecystectomy can increase the stable degree of vital signs during operation and effectively reduce the stress of patients,and can achieve significant effect on the recovery of cognitive function,and it is worthy of clinical wide promotion.

Key words： Remifentanil Propofol Total intravenous anesthesia Cholecystectomy

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XU Jian-li. Influence of Remifentanil and Propofol for total intravenous anesthesia on cognitive function in elderly patients undergoing laparoscopic cholecystectomy[J]. 中国当代医药, 2017, 24(14): 103-105.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I14/103

[1]	李红宝，何建国.七氟烷吸入麻醉和丙泊酚全凭静脉麻醉对老年患者肝肾功能的影响[J].中国现代医生，2014，52 （15）：71-74.
[2]	Hocker J，Stapelfeldt C，Leiendeeker J，et al．Postoperative dysfunctioninelderlypatientsafterxenonversuspropofolanesthesia for major noneardiac surgery：a double-blinded randomized controlled pilot study[J]．Anesthesiology，2009，110 （5）：1068-1076．
[3]	郭媛媛.全身麻醉的不同方法对老年患者术后认知功能障碍的影响[J].中国现代药物应用，2014，8（1）：15-16.
[4]	Jung KT，Kim SH，Lee HY，et al.Effect on thermoregulatory responses in patients undergoing a tympanoplasty in accordance to the anesthetic techniques during PEEP：a comparison between inhalation anesthesia with desflurane and TIVA Korean[J].Korean J Anesthesiol，2014，67（1）：32-37.
[5]	王桂兰，廖林，李应清.不同全身麻醉方法对老年患者术后认知功能的影响分析[J].医学综述，2014，20（7）：1304-1305.
[6]	Folstein MF，Folstein SE，Mchugh PR."Mini-mental state". A practical method for grading the cognitive state of patients for the clinician[J].J Psychiatr Res，1975，12（3）：189-198.
[7]	吴昱，袁军.经皮穴位电刺激辅助吸入麻醉对老年患者腹腔镜胆囊切除术后认知功能的影响[J].中国内镜杂志，2014，20（3）：247-251.
[8]	陈益君，巩继勇，陆正荷，等.乌司他丁对老年人七氟烷吸入麻醉术后认知功能的影响[J].中国基层医药，2011，18 （2）：147-150.
[9]	刘兴建.瑞芬太尼全凭静脉麻醉在对腹腔镜手术中的应用[J].当代医学，2012，18（22）：45.
[11]	杨秀林.比较全凭静脉麻醉与吸入麻醉对老年患者术后认知功能的影响[J].当代医药论丛，2014，12（2）：97-98.
[12]	许艳淑，陈琦，王英伟.全凭静脉麻醉与吸入麻醉对老年患者术后认知功能影响的比较[J].上海医学，2009，32（1）：50-53.
[13]	徐桂萍，郭强，伍湘伊，等.瑞芬太尼与芬太尼对老年患者术后认知功能的影响[J].临床麻醉学杂志，2012，28（24）：131-133．
[15]	李红波，严蕾，张溶，等.瑞芬太尼复合异丙酚全凭静脉麻醉在老年患者腹腔镜胆囊切除术中的应用效果[J].实用临床医学，2013，14（7）：60-61.
[10]	Chen J，Yan J，Han X.Dexmedetomidine may benefit cognitive function after laparoscopic cholecystectomy in elderly patients[J].Exp Ther Med，2013，5（2）：489-494.
[14]	Goswami U，Babbar S，Tiwari S.Comparative evaluation of the effects of propofol and sevoflurane on cognitive function and memory in patients undergoing laparoscopic cholecystectomy：a randomised prospectivestudy[J].Indian J Anaesth，2015，59（3）：150-155.