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Quick Search     Adv Search 2016 Vol. 23, No. 3 Published: 2016-01-28   4 Cognitive investigation and relative factors analysis on delayed treatment for patients with acute ischemic stroke CHEN Xiao-ming;CHEN Jin-li;YE Xiao-xiang;LU Ya-qin;LIU Ning Objective To investigate the cognition of risk factors and symptoms of stroke for patients with acute ischemic stroke on and potential factors affecting visit time.Methods From January 2014 to June 2015，a prospective survey using structured questionnaire for patients with acute ischemic stroke was conducted to investigate the cognition of stroke knowledge and the time of each stage of the medical treatment after the onset of the disease.The relations between visit time and sociology data of population，past medical history，state of onset，measures taken at onset of disease，the first-episode symptoms，the defect degree of neural function，cognition of stroke was analyzed respectively.The related factors affecting visit time were screened by multiple linear regression analysis method.Results 133 patients with acute ischemic stroke received by department of neurology in the First Hospital of Lanzhou University were enrolled，age of onset was (63.20±11.46) years old，86 cases (64.7%) were male.The risk factor of acute ischemic stroke with highest cognitive rate was hypertension (66.2%)，the symptom of acute ischemic stroke with highest cognitive rate was limb weakness (59.4%).24.1% of patients could recognize more than 4 risk factors of stroke and 15% of them could recognize more than 3 symptoms ofstroke.Proportion of could recognize more than 4 risk factors (P=0.021) and more than 3 symptoms (P=0.044) of stroke in rehospitalization group was obviously higher than that of first hospitalization group respectively.The onset-to-needle time (ONT) was (2327.27±2157.30) min，with a median was 1440.00 min.The average onset-to-door time (ODT) was 1352.89 (10.00-8730.00) min，with a median was 400.00 min.The average door-to-needle time (DNT) was 641.16 (8.00-5760.00) min，with a median was 360.00 min.The ONT (P=0.000) and ODT (P=0.000) in the emergency hospitalization group was significantly shorter than that in the clinic hospitalization group.Multiple linear regression analysis showed age bracket (P=0.082)，housing state (P=0.061)，first-episode dizziness symptom (P=0.017)，measures taken at onset of disease (P=0.053)，cognition of time window for thrombolytic therapy (P=0.090) was significantly associated with ONT respectively，and elder age，living alone，had no first-episode dizziness symptom，no emergency call after onset of disease and ignorance of time window of thrombolytic therapy indicated that extension of ONT.Conclusion Delayed treatment phenomenon is generally exist in patients with acute ischemic stroke received by department of neurology in our hospital，when exsits older age，living alone，had no first-episode dizziness symptom，no emergency call after onset of disease and ignorance of time window of thrombolytic therapy，and it indicates that extension of ONT. 2016 Vol. 23 (3): 4-10 [Abstract] ( 159 ) HTML (65 KB)  PDF  (0 KB)  ( 34 ) 11 The effect of propolis on wound healing of skin in rats BIAN Ming-xin;SHEN Ruo-wu;LIU Xiao-tong;LI Chun-xue;LI Ling;YANG Yong-hua Objective To discuss the influence of propolis on wound healing and study preliminarily on the mechanism of wound healing.Methods 60 healthy and male Wistar rats were randomly divided into experimental group (wound model+propolis，n=20)，control group (wound model+povidone iodine，n=20) and blank group (wound model+physiological saline，n=20).Each group was then randomly divided into 5 time points:3 d，5 d，7 d，10 d and 14 d with there were 4 rats in each time point.The wound model was established by full-thickness skin injury in rats' back in size of 1 cm×1 cm，changed dressings every day.The rats were executed in every time point and the injuried skin tissues were cut to calculate the wound healing rate，and the change of wound histology was observed by hematoxylin-eosin (HE) staining and the dyanmic change of vascular endothelial growth factor(VEGF) and platelet-derived growth factor(PDGF) was detected by immunohistochemical staining method respectively.Results Compared with control group，the experimental group could obviously improve the healing speed and healing rate of wound in rats (P＜0.05 or P＜0.01).Compared with blank group，HE staining revealed that remarkable capillary and collagen fiber hyperplasia，and complete epidermal regeneration was observed in experimental group.Immunohistochemical staining revealed that the expression level of VEGF in experimental group was significantly higher than that of control group in 3 d (P＜0.05).The expression level of PDGF was greatly higher than that of control group in 5 d (P＜0.05).Conclusion The propolis plays a significant promotion role in healing and repair of wound，it may be related to promoting angiogenesis，the role of promoting proliferation of granulation tissue and scar tissue.promote the rebuilding of capillaries，acceletate the regeneration of the epidermis and facilitate the formation of scar. 2016 Vol. 23 (3): 11-14 [Abstract] ( 118 ) HTML (50 KB)  PDF  (0 KB)  ( 32 ) 15 The effects of alcohol on cardiac function and related mechanism progresses XU Juan;ZENG Li-qun From ancient to modern times，alcohol consumption has been an integral part of social culture in human beings.The consumption of ethanol can have both beneficial and detrimental effects on the function of the heart and cardiovascular system，depending on the amount consumed.moderate amounts of ethanol intake are associated with improvements in cardiac function.On the other hand，ethanol chronically consumed in large amounts acts as a toxin to the heart and vasculature.The cardiac injury produced by alcohol can progress to alcoholic cardiomyopathy.In recent years，the effects of alcohol on cardiac function and related mechanisms have been widely concerned.The purposes of this review are to outline the association between cardiovascular diseases and alcohol，focusing on the related pathophysiology of cardiac function effects of alcohol。 2016 Vol. 23 (3): 15-18 [Abstract] ( 133 ) HTML (49 KB)  PDF  (0 KB)  ( 36 ) 19 Clinical research progress of hemifacial spasm WANG Fang;MA Ting-ting;HAN Hui-min Hemifacial Spasm，also called facial tic is one side facial muscular paroxysm non-spontaneous and non-pain recurrent rigidity or tic caused by abnormal excitement of the same side facial nerves.The pathogenesisof the disease is still unclear with slow symptoms progression and progressive development.With the widespread application of microvascular decompression，the pathogenesis of hemifacial spasm is more profoundly understood.In this article，a review is made about clinical diagnose and progress of medical and surgical treatment to improve the standardized clinical treatment of facial spasm. 2016 Vol. 23 (3): 19-21 [Abstract] ( 166 ) HTML (41 KB)  PDF  (0 KB)  ( 33 ) 22 Effect and significance of large volume lung lavage on T lymphocyte subgroup in patients with pneumoconiosis WAN Yin;XU Man-qing;ZHANG Ai-mei Objective To explore the effects and significance of large volume lung lavage on CD3+，CD4+and CD8+T lymphocytes in the peripheral blood in patients with pneumoconiosis.Methods 50 patients with pneumoconiosis who were hospitalized in our hospital from May 2014 to September 2015 and given large volume lung lavage were randomly collected.30 healthy males undergone physical examination in the community clinic in our hospital at the same period of time were also collected.The expression level of CD3+，CD4+and CD8+T lymphocytes in the peripheral blood in patients with pneumoconiosis before lung lavage and 1 week after lung lavage was tested.The expression level of CD3+，CD4+and CD8+T lymphocytes in the peripheral blood in healthy males was also tested.Their expression levels were compared and the comparison results were analyzed.Results Compared with the healthy control group，CD3+，CD4+，CD8+T lymphocytes，and CD4+/CD8+ratio in the peripheral blood in patients with pneumoconiosis was reduced respectively (P＜0.05)；After 1 week of large volume lung lavage，CD3+，CD4+T lymphocytes，and CD4+/CD8+ratio was increased respectively(P＜0.05)，and CD8+T was reduced(P＜0.05).Conclusion The cellular immune function in patients with pneumoconiosis is reduced，and large volume lung lavage is able to increase CD3+，CD4+T lymphocytes，and CD4+/CD8+ratio and reduce CD8+T lymphocytes for patients with pneumoconiosis，so as to improve the cellular immune function of patients with pneumoconiosis. 2016 Vol. 23 (3): 22-24 [Abstract] ( 157 ) HTML (42 KB)  PDF  (0 KB)  ( 27 ) 25 Influence of laparoscopic cholecystectomy under different pneumoperitoneum pressure on postoperative liver function in elderly patients LI Han Objective To explore the influence of laparoscopic cholecystectomy under different pneumoperitoneum pressure on postoperative liver function in elderly patients as well as its possible mechanism.Methods One hundred and ten elderly patients undergone laparoscopic cholecystectomy in our hospital from November 2012 to November 2014 were retrospectively analyzed.According to different levels of pneumoperitoneum pressure in carbon dioxide，they were divided into low pneumoperitoneum pressure group (LP group)，standard pneumoperitoneum pressure group(SP group)，and high pneumoperitoneum pressure group (HP group).The serum alanine aminotransferase (ALT) and aspartate aminotransferase(AST) were tested by drawing venous blood before surgery and one and four days after surgery.The two indicators were also monitored and analyzed.Results The level of ALT and AST was greatly increased one day after surgery in SP and HP group respectively (P＜0.01).The increase in HP group was more obvious than that in SP group.In HP group，the level of lactate dehydrogenase (LDH) and total bilirubin (TBIL) was increased respectively in the first day after surgery (P＜0.05).The level of ALT and AST returning to be normal after surgery in SP group was sooner than that of HP group respectively.Conclusion Pneumoperitoneum pressure of carbon dioxide in laparoscopic cholecystectomy can lead to transient abnormal liver functions after surgery in elderly patients，especially for patients with high pneumoperitoneum pressure or pneumoperitoneum pressure maintaining for a longer time. 2016 Vol. 23 (3): 25-27 [Abstract] ( 166 ) HTML (36 KB)  PDF  (0 KB)  ( 38 ) 28 Study on blood DD,BNP,TnI,CRP in patients with acute pulmonary embolism XING Guo-yan;ZHAO Shu-bo Objective To explore the concentration change and clinical meaning of DD，BNP，TnI and CRP in acute pulmonary embolism(APE) patients.Methods 56 APE patients from June 2013 to June 2015 of our hospital were selected as experimental group，and 50 healthy examined people at the same period of physical examination center were selected as control group.The concentration of DD，BNP，TnI and CRP was compared respectively.After treatment for 2 weeks，the concentration of DD，BNP，TnI and CRP in APE patients were compared with experimental group.Results The concentration of DD，BNP，TnI and CRP in experimental group was higher than that of control group respectively，and the difference was statistical significance(P＜0.01).The concentration of DD，BNP，TnI and CRP in experimental group was higher than that of effectively treatment group respectively，and the difference was statistical significance (P＜0.01).The concentration mean value of DD，BNP，TnI and CRP in experimental group was higher than that of ineffective treatment group respectively，while the difference between two groups had no statistical significance(P＞0.05).Conclusion Combination detection the concentration of DD，BNP，TnI and CRP has great clinical meaning for diagnosis，condition judgment，effective evaluation and prognosis development of patients. 2016 Vol. 23 (3): 28-30 [Abstract] ( 155 ) HTML (42 KB)  PDF  (0 KB)  ( 27 ) 31 Application research of trauma index in the assessment of patients with acute trauma HE Lin-heng Objective To investigate the application value of trauma index (TI) in the assessment of acute trauma patients.Methods 2168 hospitalized patients with acute trauma in our hospital from October 2012 to October 2015 were selected，the TI and injury severity score (ISS) were performed.In order evaluate the application value of TI score in patients with acute trauma，the TI score and ISS score were compared.Results The scores of TI and ISS of the survival group was significantly lower than that of the death group respectively，the difference was statistically significant (P＜0.05).The mortality of TI and ISS was significantly lower than that of severe group respectively，the difference was statistically significant(P＜0.05).The sensitivity of TI score was significantly higher than that of ISS，the difference was statistically significant (P＜0.05).Conclusion The TI has a certain degree of prediction and assessment in the assessment of patients with acute trauma.It can be popularized in clinical application. 2016 Vol. 23 (3): 31-33 [Abstract] ( 156 ) HTML (40 KB)  PDF  (0 KB)  ( 32 ) 34 Levels of 8-isoprostane and leukotriene B4 in exhaled breath condensate and its clinical significance in interstitial lung disease HUANG Li-xia;LI Xiao-li;HUANG Xiao-xing;WU Cui-hua;HONG Yong-zhong;ZHONG Chun;ZHU Yi-xin Objective To investigate the levels of 8-isoprostane(8-iso-PG) and leukotriene B4(LTB4) in exhaled breath condensate(EBC)and its clinical significance in interstitial lung disease(ILD).Methods 20 ILD patients in our department from August 2012 to December 2013 were selected as the ILD group，20 healthy subjects matched with age and body mass index were selected as control group.The levels of 8-iso-PG and LTB4 in EBC were measured by ELISA.Results The level of 8-iso-PG in ILD group was (9.69+2.8) ng/L，which was higher than that in control group(4.86+1.9) ng/L，with significant difference (P＜0.05).The level of LTB4 in EBC of ILD group was (15.46+6.6) ng/L，higher than that in control group (8.55+4.4) ng/L，the difference was statistically significant(P＜0.01).The specificity of LTB4 and 8-iso-PG was 85% respectively，and the sensitivity was 90% and 60% respectively.Conclusion 8-iso-PG and LTB4 increases in EBC of ILD patients.Measuring biomarkers in EBC may be useful to evaluate inflammatory response of ILD. 2016 Vol. 23 (3): 34-36 [Abstract] ( 170 ) HTML (41 KB)  PDF  (0 KB)  ( 29 ) 37 Evaluation values of simplified pulmonary embolism severity index combining with biochemical markers on pulmonary embolism severity and prognosis LIU Li-fen Objective To discuss the evaluation values of simplified pulmonary embolism severity index combined with biochemical markers on pulmonary embolism severity and prognosis.Methods 154 patients with pulmonary embolism treated in our hospital from March 2011 to March 2013 were selected，and primary endpoints and secondary endpoints were sieved.The severity index of applying simplified pulmonary embolism was evaluated，and blood biochemical parameters and images were tested in order to explore values of each index on the pulmonary embolism severity and prognosis.Results sPESI，BNP≥514 pg/ml，and hs-TnI≥0.1 μg/L was influence factor of primary endpoints respectively，and only sPESI was considered as an influence factor of secondary outcome event.Conclusion In short-term prognosis evaluation of pulmonary embolism，sPESI，BNP，and hs-TnI are excellent evaluation indexes，and can reflect the overall risk of pulmonary embolism.However，in long-term prognosis evaluation，sPESI is the only one at a higher value and can be integrated into a comprehensive risk evaluation of pulmonary embolism. 2016 Vol. 23 (3): 37-39 [Abstract] ( 157 ) HTML (37 KB)  PDF  (0 KB)  ( 34 ) 40 Effect of reasonable combined enteral and parenteral nutrition in the early stage on the nutritional status and prognosis of patients with long period of coma after the surgery on severe craniocerebral injury ZHANG Long Objective To investigate the effect of reasonable combined enteral and parenteral nutrition in the early stage on the nutritional status and prognosis of patients with long period of coma after the surgery on severe craniocerebral injury.Methods 118 patients diagnosed severe craniocerebral injury and hospitalized in the surgical department of our hospital from August 2014 to September 2015 were enrolled into the study and randomly divided into the control group and observation group.The 60 patients in the control group were treated with enteral nutrition，while the 58 patients in the control group were treated with combined enteral and parenteral nutrition.The improvement of hemoglobin，albumin，total protein and Glasgow Coma Scale (GCS score) of the two groups before and after treatment were observed.The improvement of immune function (IgA，IgM，IgG)and the incidence of complicated pulmonary infection and gastrointestinal dysfunction were compared between the two groups.Results After treatment，the level of hemoglobin，albumin，total protein，GCS score，immune function indexes of the observation group was higher than that of the control group respectively，while the incidence of complications was lower (P＜0.05).Conclusion The reasonable combined enteral and parenteral nutrition in the early stage can improve the nutritional status of patients with long period of coma after the surgery on severe craniocerebral injury，enhance their immunity and reduce the incidence of complications such as pulmonary infection，which is worth promoting. 2016 Vol. 23 (3): 40-42转45 [Abstract] ( 160 ) HTML (41 KB)  PDF  (0 KB)  ( 33 ) 43 Clinical effect comparison of tissue-selecting therapy stapler and procedure for prolapse and hemorrhoids with stapler in the treatment of haemorrhoids HOU Hui Objective To explore the clinical value of tissue-selecting therapy stapler (TST) and procedure for prolapse and hemorrhoids with stapler (PPH) on treating hemorrhoids.Methods From January 2013 to July 2014，100 patients with hemorrhoids admitted into our hospital were selected and divided into treatment group and control group by random number table.In the treatment group，TST was used，while in the control group，PPH was adopted.The therapeutic effect and adverse reaction were compared.Results In the treatment group，the average operative time，hospital stay at average，and mean wound healing time was greatly shorter than that in the control group respectively，with statistical differences(P＜0.05).Pain sensation 6，12，and 24 h after surgery in the treatment group was lower than that in the control group respectively，which displayed a statistical difference (P＜0.05).Follow up visits were carried out one month after surgery，there was no stricture of anus or anal incontinence occurred in the treatment group.In the control group，no anal incontinence was found，but two cases were presented with stricture of anus.Index finger could pass through in digital rectal examination.The shape of stool became fine，and could be defecated smoothly.After 3 months follow up visits，no case was recurred between two groups.Conclusion Effect of TST on treating hemorrhoids is superior to that by PPH，which is worthy of clinical application and promotion. 2016 Vol. 23 (3): 43-45 [Abstract] ( 121 ) HTML (34 KB)  PDF  (0 KB)  ( 36 ) 46 Effect analysis of small dose and light specific gravity of combined spinal epidural anesthesia applied in lower limb fracture surgery in elderly patients MA Tao Objective To analyze the clinical effect of small dose and light specific gravity of combined spinal epidural anesthesia applied in lower limb fracture surgery in elderly patients.Methods 66 elderly patients receiving lower limb fracture surgery in our hospital from December 20，2013 to March 20，2015 were selected and randomly divided into observation group (n=33) and control group (n=33).Control group was given continuous epidural anesthesia while observation group was given small dose and light specific gravity of combined spinal epidural anesthesia.The anesthetic effect between two groups was compared.Results The drug dose used in observation group was lower than that in control group，and there was a statistical difference (P＜0.05).The time of maximum sensory block and time of anesthesia onset in observation group was significantly shorter than that in control group respectively，and there was a statistical difference (P＜0.05).The excellent rate in observation group was higher than that in control group，and the good rate was lower than that in control group，and there was a statistical difference (P＜0.05).The incidence rate of adverse reaction in observation group (6.06%) was lower than that of control group (48.48%)，and there was a statistical difference (P＜0.05).Conclusion Small dose and light specific gravity of combined spinal epidural anesthesia has a satisfactory effect with high safety，which is very appropriate for elderly patients with lower limb fracture. 2016 Vol. 23 (3): 46-48 [Abstract] ( 154 ) HTML (42 KB)  PDF  (0 KB)  ( 33 ) 49 Application effect comparison of minimally spinal anesthesia,epidural anesthesia and caudal anesthesia in anorectal operation anesthesia WANG Yong;HE Chun-yan Objective To compare the application effect of minimally?spinal anesthesia，epidural anesthesia and caudal anesthesia in anorectal operation anesthesia.Methods 150 patients conducted anorectal operation by our hospital from September 2012 to August 2015 were retrospectively selected.50 cases given minimally spinal anesthesia were set as group A，50 cases given epidural anesthesia were set as group B，and 50 cases given Sacral anesthesia were set as group C.The operation time，the incidence rate of headache after operation，the successful rate of anesthesia puncture，onset time of anesthesia，usage dose of local anesthetics，anesthesia effect，cycle stability and so on among threes was compared respectively.Results There was no statistical difference of operation time，the incidence rate of headache after operation in patients among three groups (P＞0.05).The successful rate of anesthesia puncture in group A was higher than that of group B，the pain rate of anesthesia puncture，the incidence rate of low back pain was obviously lower than that of group C，usage dose of local anesthetics was obviously fewer than that of group B and C，onset time of anesthesia was obviously shorter than that of group C，anesthesia effect，cycle stability was better than that of group B and C (P＜0.05).Conclusion Minimally spinal anesthesia technology used in anorectal operation anesthesia has small puncture injury，patients more comfortable，fewer usage dose of local anesthetics，papid onset，good cycle stability and its effect is exact. 2016 Vol. 23 (3): 49-51转54 [Abstract] ( 145 ) HTML (40 KB)  PDF  (0 KB)  ( 37 ) 52 Influence of dyclonine mortar used for painless urethral catheterization on recovery period restlessness in male patients with general anesthesia SANG Xu-ming;LIU Yan-yan;LOU Cui-hua Objective To investigate influence of dyclonine mortar used for painless urethral catheterization on recovery period restlessness in male patients with general anesthesia.Methods 120 male patients with general anesthesia diagnosed and treated by our hospital from August 2013 to August 2014 were selected，and they were randomly divided into two groups.60 cases in control group were given sterile paraffin oil used for painless urethral catheterization，while 60 cases in observation group were given dyclonine mortar used for painless urethral catheterization.Change of heart rate，blood pressure and recovery period restlessness was compared between two groups respectively.Results Heart rate at T1，T2，T3，T4in observation group was significantly slower than that of control group，and diastolic blood pressure，systolic blood pressure at T1，T2，T3，T4in observation group was significantly lower than that of control group respectively (P＜0.05).Incidence rate of restlessness and restless score in observation group was significantly lower than that of control group respectively，and restless rating in observation group was significantly better than that of control group (P＜0.05).Conclusion Dyclonine mortar used for painless urethral catheterization can significantly reduce recovery period restlessness in male patients with general anesthesia，which is more conducive to stable hemodynamics and worthy of clinical promotion and application. 2016 Vol. 23 (3): 52-54 [Abstract] ( 128 ) HTML (37 KB)  PDF  (0 KB)  ( 36 ) 55 Application value of ultrasonic detection in the carotid intima -media thickness of different parts in the diagnosis of cardiovascular and cerebrovascular disease FAN Xing;GUO Jian-feng;GU Jun;HUANG Min Objective To explore the clinical value of ultrasonic detection in the carotid intima-media thickness of different parts in the diagnosis of cardiovascular and cerebrovascular disease.Methods 144 cases with hypertension，coronary heart disease，cerebral infarction (complicated with diabetes) in our hospital from November 2013 to June 2014 were selected as research subjects，and 22 normal persons were selected as the control group.All people were given color Doppler ultrasonography of bilateral carotid artery，the difference of carotid intima-media thickness of carotid artery in different groups was compared.Results 144 cases of patients with cardiovascular and cerebrovascular diseases，50.69% of the patients were detected carotid artery intima-media structure abnormalities，and the detection rate of hypertension complicated with coronary heart disease was higher，which was 63.33%.The value of carotid intima-media thickness in the patients group was higher than that in the control group，with significant difference (P＜0.05).There was no significant difference in the carotid intima-media thickness in the carotid bulb，proximal carotid artery bifurcation 1 cm and the proxima internal carotid artery (P＞0.05).Conclusion Carotid intima-media thickness can provide the basis for clinical diagnosis and treatment of cardiovascular and cerebrovascular disease. 2016 Vol. 23 (3): 55-57 [Abstract] ( 132 ) HTML (39 KB)  PDF  (0 KB)  ( 33 ) 58 Application value of ultrasound elastography and conventional ultrasound in the identifying of benign or malignant thyroid nodule WEI Bo Objective To explore the application value of ultrasound elastography and conventional ultrasound in the identifying of benign or malignant thyroid nodule.Methods 64 thyroid nodules lesion patients from 1 May 2014 to 1 July 2015 in our hospital were selected as the research group，all patients were used ultrasound elastography and conventional ultrasound.The sensitivity and specificity of two examinations was compared respectively.Results The sensitivity of ultrasound elastography for identifying benign or malignant thyroid nodules was 86.36%，the specificity was 89.28% and the accuracy rate was 88.46%.The sensitivity of conventional ultrasound for identifying benign or malignant thyroid nodules was 66.36%，the specificity was 78.57% and the accuracy rate was 74.35%.There was significant difference in the sensitivity，specificity and accuracy rate between two examination methods (P＜0.05).Conclusion Ultrasound elastography can accurate identify and diagnose the nature of thyroid nodules，can make up for the shortcoming of conventional ultrasound and then can more clearly show the disease focus，at the same time，which has higher sensitivity and accuracy rate that can provide valuable information for patients'early diagnosis，therapy method and prognosis. 2016 Vol. 23 (3): 58-60 [Abstract] ( 154 ) HTML (39 KB)  PDF  (0 KB)  ( 40 ) 61 Analysis of chest imaging characteristics of human infection with H7N9 avian influenza SHI Xiao-ping;ZOU Zi-yi;ZOU Jia-ji ;ZHANG Mei-shun;CHEN Kang-ping Objective To analyze the chest imaging characteristics of human infection with H7N9 avian influenza and to provide evidence for clinical reasonable diagnosis and disease evaluation.Methods 20 cases of human infection with H7N9 avian influenza from October 2013 to January 2015 were selected as the research group，chest imaging material and characteristic was analyzed.Results Main chest imaging features included 4 cases of patchy shadows，8 cases of groud-glass opacity，3 cases of consolidation，2 cases of air bronchogram，1 case of reticular changes，2 cases of pleural effusion，1 cases of enlargement of mediastinal and hilar lymph nodes.8 cases of involvement of the bilateral lung and 12 cases of involvement of the single lung.Conclusion Features of chest images of patients with human infection H7N9 avian influenza shows some characteristics with no apparent specificities，which has important significance for clinical timely treatment. 2016 Vol. 23 (3): 61-63 [Abstract] ( 135 ) HTML (44 KB)  PDF  (0 KB)  ( 8 ) 64 Application value of susceptibility-weighted magnetic resonance imaging sequences in the diagnosis of cerebral microbleeds patients GUO Jiang-yuan;GUO Ai-ting Objective To explore the clinical application value of susceptibility-weighted magnetic resonance imaging sequences in the diagnosis of cerebral microbleeds (CMBs) patients.Methods 68 CMBs patients diagnosed by clinical and surgical pathology from January 2012 to May 2015 in our hospital were selected as the research group，susceptibilityweighted imaging (SWI) and routine sequence (T1WI，T2WI and FLAIR) was given respectively，and the result was compared.Results The detection rate of T1WI，T2WI and FLAIR was 8.8%，16.1% and 55.9% respectively in routine sequence，the detection rate of SWI in CMBs was 97.1%，there was significant difference (P＜0.05).Results SWI in CMBs diagnosis has important application value，which can used as one of the complementary sequencein the diagnosis of CMBs. 2016 Vol. 23 (3): 64-66 [Abstract] ( 142 ) HTML (43 KB)  PDF  (0 KB)  ( 23 ) 67 Feature and analysis of MRI in knee training injury of new recruits from different altitudes region ZHAO Yong-dong;CHEN Zhu-hong;CHEN Hai-long;CUI Hong;XU Qiang Objective To explore the feature and reason of MRI in knee training injury of new recruits from different altitudes region and to provide a theoretical basis for reducing the incidence of knee injury.Methods 180 new recruits from October 2013 to October 2014 in a unit were selected and divided into the low altitude group and the high altitude group according to the altitude of the recruitment place.MRI scan for the right knee joint was given in the first，second，third months of recruit training.The bone of knee joint，meniscus，ligament and joint cavity injury of the two groups was compared between the three stages and the different training stages.Results The incidence rate of bone marrow edema and joint effusion at the early stage and the middle stage in the low altitude group was higher than that in the high altitude group，with significant difference (P＜0.05).The incidence rate of meniscal injury at the middle stage and the late stage in the low altitude group was higher than that in the high altitude group，with significant difference (P＜0.05).There was significant difference in the incidence rate of bone marrow edema，meniscus injury and joint effusion between different training stages in the low altitude group (P＜0.05).There was significant difference in the incidence rate of bone marrow edema and joint effusion in different training stages of the high altitude group (P＜0.05).Conclusion The incidence rate of the knee joint injury of new recruits training in the low altitude region is higher than that in the high altitude region，proper protective measure and scientific training strategy should be developed to reduce its occurrence.Knee injury rate increases significantly with increasing amount of training，which is mostly significant in the late stage. 2016 Vol. 23 (3): 67-70 [Abstract] ( 173 ) HTML (53 KB)  PDF  (0 KB)  ( 29 ) 71 Appliacation of CT -guided localization with a manual Hook -wire for sub-centimeter small pulmonary nodule punctured in the video-assisted thoracic surgery CUI Hua-zi;CHEN Ai-lin;YE Yong-qiang;ZHANG Shou-lin;WEN Mei-ru;HE Hong-hong Objective To explore the value of CT-guided localization with a manual Hook-wire for sub-centimeter small pulmonary nodule punctured in the video-assisted thoracic surgery.Methods 46 patients with video-assisted thoracic surgery in our hospital from May 2013 to August 2015 were selected as the research group，there were altogether 46 sub centimeter small pulmonary nodules.All patients were divided into group A (agreed and signed the agreement) and group B (disagreed and did not sign the agreement) according to whether or not localization with manual Hook-wire.The average operation time，the incidence rate of open chest surgery，the average length of stay in the two groups was compared respectively.Resullts The incidence rate of open chest surgery in group A was lower than that in group B，with significant difference (P＜0.01).The average operation time and the average length of stay in group A was shorter than that in group B，with significant difference (P＜0.01).Conclusion CT-guided localization with a manual Hook-wire for sub-centimeter small pulmonary nodule punctured can significantly reduce the incidence rate of conversion to open chest surgery，shorten the operation time and the average length of stay in the hospital，which has a very good clinical value in the diagnosis and treatment of the sub-centimeter small pulmonary nodule. 2016 Vol. 23 (3): 71-74 [Abstract] ( 136 ) HTML (53 KB)  PDF  (0 KB)  ( 34 ) 75 RP-HPLC determination of syringin in Ilex rotunda Thunb. WANG Yan;LEI Li;LI Fu-jun Objective To establish a method for RP-HPLC determination of syringin in Ilex rotunda Thunb..Methods A Kromasil-C18Column (250 mm×4.6 mm) was used with gradient elution using methanol-0.5% acetic acid as mobile phase.The detection wavelength was 290 nm and the column temperature was 30℃with the flow rate of 1.0 ml/min，the samplem injection was 10 μl.Results Linear ranges of syringin was 0.3051-6.102 μg (r=0.9992)，respectively.Its average recoveries was 99.67%.Conclusion The RP-HPLC method established in this experiment can be used to determine the contents of syringin in Ilex rotunda Thunb..The method can also be used as the standard for the quality control of Ilex rotunda Thunb.because of simplicity，reliability and accuracy. 2016 Vol. 23 (3): 75-76 [Abstract] ( 140 ) HTML (34 KB)  PDF  (0 KB)  ( 30 ) 77 Process study of Ganmao Qingre Granule LI Jun;SUN Yong-hui;WANG Chun-min;YAN Chun-feng;GUO Jin-jia Objective To detect optimal preparation of Ganmao Qingre Granule (3 g per bag).Methods Volatile oil was extracted by CO2- supercritical fluid.The extraction technology was optimized targeting on oil extraction rate.The best process of volatile oil β-cyclodextrin (β-CD) inclusion was determined by orthogonal experimental design.Puerarin transfer rate as an indicator，extraction process was optimized.The granulation was processed by dry granulating.Results The optimal process on volatile oil extracting was 20 MPa in extraction pressure，35℃in extraction temperature，and 120-minnute extraction under the condition of 30 kg/h CO2flow rate.The best inclusion process of cyclodextrin was that the ratio of oil and β-CD being 1∶8，40℃in constant temperature，and stirring inclusion for 1.5 h.The optimal decoction process included 8 times of water，twice in decoction，and 1.5 h each time.Conclusion Preparation technics of Ganmao Qingre Granule is stable and feasible. 2016 Vol. 23 (3): 77-80 [Abstract] ( 110 ) HTML (57 KB)  PDF  (0 KB)  ( 33 ) 81 Clinical efficacy of Rifapentine in the treatment of pulmonary tuberculosis ZHANG Li-juan Objective To analyze the clinical effect of Rifapentine in the treatment of pulmonary tuberculosis (TB).Methods From January to December in 2013，80 TB patients admitted into our hospital were selected and evenly divided into observation group and control group in random.In the control group，drug therapy of Rifampin，Levofloxacin and Pyrazinamide was used，while in the observation group，on the basis of the control group，Rifapentine was added.The therapeutic effect in the two groups was compared.Results The sputum negative conversion rate in the observation group was 87.50%，which was significantly higher than that in the control group accounting for 67.50% with a statistical difference (P＜0.05).The improvement rate of X-ray examination result in the lungs in the observation group was 92.50%，which was much higher than that in the control group accounting for 75.00% with a statistical difference (P＜0.05).The main adverse reactions during medication in the two groups were abdominal pain，vomiting，liver dysfunction，and abnormal routine urine test，but there was no statistical difference after comparison in the two groups (P＞0.05).After 6-month follow-up visits，the recurrence rate of sputum bacteria in the observation group was 10.00%，which was much less than that in the control group of 30.00% with a statistical difference (P＜0.05).Conclusion Rifapentine as a second-line TB drug obtains a good effect and is safe in medication，which is worthy of extensive application. 2016 Vol. 23 (3): 81-82转85 [Abstract] ( 117 ) HTML (33 KB)  PDF  (0 KB)  ( 35 ) 83 Detection method of improvement the Cimetidine Capsule dissolution rate QIN Song;ZHANG Bei Objective To explore the detection method of improvement the Cimetidine Capsule dissolution rate.Methods HPLC was used to determine the dissolutionrate of Cimetidine Capsule.The measurement results of improved method were compared with Chinese Pharmacopeia.Results On the concentrationscale from 0.02 to 0.2 mg/ml，the peak area had nice linear relationship with concentration，and r，recovery rate and RSD were respectively 0.9998，99.82% and 0.33%　(n=6).Conclusion The improved method has advantages of more accurate，more exact，more scientific and strong specificity. 2016 Vol. 23 (3): 83-85 [Abstract] ( 126 ) HTML (36 KB)  PDF  (0 KB)  ( 34 ) 86 Preparation process and content determination of Norcantharidin tablets WANG Qin;XUE Ming-dao;JIN Zhi-hua Objective To establish a preparation method of Norcantharidin tablets，and to detect content of Norcantharidin Tablets by using HPLC method.Methods Norcantharidin tablets were prepared with norcantharidin as the main drug，microcrystalline cellulose (MCC) and lactose as the fillers，sodium carboxymethyl starch (CMS-Na) as the disintegrating agent，polyvinylpyrrolidone K30(PVP-K30) as adhesive.Content of Norcantharidin tablets was detected with the method of HPLC；HPLC chromatographic conditions were: Spherigel ODS C18chromatographic column；mobile phase: acetonitrile - pH 3.1 phosphoric acid aqueous solution (10∶90) (V/V)；the flow rate of 1.0 ml/min；column temperature 25℃；detection wavelength of 210 nm；sample quantity 20 μl.The factors A (starch)，B (MCC) and C (CMS-Na) were selected，U7(73) uniform design was adopted，and preparation of Norcantharidin tablets was optimized through the dissolution index.Results HPLC standard curve equation: Y=925.374X-1778.8 (r=0.9999)；linear range: 20～800 μg/ml.The intra-day precision RSD were 1.880%，0.172%，0.945%；inter-day precision RSD were 1.420%，1.126% and 1.468%.Coefficient of recovery in low，medium and high concentrations were separately (98.77±1.24)%，(100.08±1.14)%，(99.59± 0.58)% (n=5).Uniform design regression equation was K=-0.107-0.004A+0.017B-0.025C-0.0002B2+0.007C2(F=245.312，P＜0.05)；the optimized prescription composition was 10% starch，40% MCC，43% lactose and 7% CMS-Na；dissolution rate constant K was validated of (0.332±0.019)/min.Conclusion Norcantharidin tablets prepared with the optimized prescription preparation are with beautiful shape，good liquidity，lubricity and compression formability；HPLC method can effectively control the quality of tablets. 2016 Vol. 23 (3): 86-88转92 [Abstract] ( 100 ) HTML (44 KB)  PDF  (0 KB)  ( 36 ) 89 Analysis of adverse drug reaction report in 114 cases in our hospital ZENG Teng-yi Objective To provide reference for rational and safe drug usage in clinic by analyzing adverse drug reaction (ADR) reports in our hospital.Methods From January to December in 2014，ADR reports from every department were collected by our pharmacy department，and were calculated and analyzed in order to explore the characteristics and general law.Results There were 114 cases occurred with ADR in total in 2014.Forty-two kinds of drugs involved in ADR.The anti-infective drug was in the first place followed by Chinese patent medicine.Intravenous dripping was the most likely to lead to ADR accounting for 85.96%.Conclusion ADR monitoring should be strengthened in clinic and rational drug use should be paid attention in order to reduce and avoid its recurrence. 2016 Vol. 23 (3): 89-92 [Abstract] ( 109 ) HTML (48 KB)  PDF  (0 KB)  ( 33 ) 93 Clinical study of traditional Chinese medicine on toxicity reducing and efficacy enhancing of infusion chemotherapy after bladder cancer surgery LUO Song-tao;JI Mei-ying;HAN Li;WANG Ming-jie Objective To explore the clinical effect of traditional Chinese medicine (TCM) on toxicity reducing and efficacy enhancing of infusion chemotherapy after bladder cancer surgery.Methods From March 2013 to March 2015，60 early-stage superficial bladder cancer patients undergone transurethral resection of the prostate (TURP) were admitted into our hospital and divided into experimental group and control group by the random number table.In the control group，only chemotherapy drug from bladder infusion was used，while in the experimental group，Chinese decoction based on syndrome differentiation and treatment was added.The comprehensive scoring of symptoms，occurrence of side effect，and postoperative recurrence rate before and after treatment between two groups were compared.Results The comprehensive scoring of symptoms after therapy in both groups was much less than that before treatment respectively(P＜0.05).The comprehensive scoring of symptoms after therapy in the experimental group was lower than that in the control group (P＜0.05).There were no statistical differences in side effects including fever，gastrointestinal side effect，bone marrow suppression，hepatic and renal functions damaging，rash，hair loss，or mild electrocardiogram change (P＞0.05).The duration of above mentioned side effects in the experimental group was greatly shorter in comparison with that in the control group (P＜0.05).In the control group，recurrence rate one or three years after surgery was 36.67%(11/30) and 46.67% (14/30) respectively，while in the experimental group，it was 13.33%(4/30) and 26.67%(8/30) respectively，which displayed statistical differences (P＜0.05).Conclusion TCM's effect of toxicity reducing and efficacy enhancing on infusion chemotherapy after bladder cancer surgery is remarkable in clinic with short duration of toxic and side effects. 2016 Vol. 23 (3): 93-95 [Abstract] ( 122 ) HTML (44 KB)  PDF  (0 KB)  ( 41 ) 96 Modern condition improvement of traditional Chinese medicine external use stains collapse treatment to chronic obstructive lung disease patients on the stable phase WANG Dong-mei Objective To certify the selection proper position of traditional Chinese medicine external use stains collapse treatment can effective improvement the modern condition of COPD patients on the stable phase and enhance the life quality of patients.Methods 60 COPD patients on the stable phase，SAS and SDS scores had no significant difference(P＞0.05)，from January 2014 to March 2015 were average divided into treatment group and control group.The treatment group was treated with salbutamol，theophylline sustained -release tablets and topical stains collapse Chinese medicine liver and lung in two parts of treatment.The control group was treated with salbutamol，theophylline sustained-release tablets and topical treatment of lung collapse stains.Anxiety，depression and life quality of patients between two groups were compared before and after treatment.Results After treatment，the SAS and SDS scores in treatment group was lower than that of control group respectively(P＜0.05).Before treatment，the GQOLI-74 score between two groups had no significant difference，but GQOLI-74 score in treatment group was obvious higher than that of control group after treatment(P＜0.05).Conclusion Selection proper position of traditional Chinese medicine stains collapse can effective improve the modern condition of COPD patients on the stable phase and enhance the life quality of patients. 2016 Vol. 23 (3): 96-98 [Abstract] ( 132 ) HTML (42 KB)  PDF  (0 KB)  ( 34 ) 99 Clinical effects of yin-nourishing and heat-clearing decoction combined with Baofukang suppository in treatment of cervical ectopic columnar epithelium XU Xiao-hui;HE Xiao-hong Objective To analyze the clinical effects of yin-nourishing and heat-clearing decoction combined with Baofukang suppository in treatment of cervical ectopic columnar epithelium.Methods 106 patients with cervical ectopic columnar epithelium from April 2013 to April 2015 were selected and randomly divided according to odd-even numbers into the observation group and the control group，with 53 patients in each group.Patients in the control group were treated by external use of Baofukang suppository；While patient in the observation group were treated by external use of Baofukang suppository combined with oral medication of yin-nourishing and heat-clearing decoction.The curative effects was compared between the two groups after four weeks of treatment.Results The total effective rate in the observation group was higher than that of the control group (P＜0.05)；The symptom scores (erosion area，erosion degree，lower abdominal pain degree，leucorrhea，and total score) of the observation group was lower than that of the control group respectively after treatment(P＜0.05)，which were without significant difference before treatment (P＞0.05).The incidence of adverse reactions between two groups were compared，the difference was not statistically significant (P＞0.05).Conclusion Combined application of yin-nourishing and heat-clearing decoction and Baofukang suppository in treatment of cervical ectopic columnar epithelium can effectively relieve the clinical symptoms and signs of patients and accelerate the healing of erosion，which plays an important role in the improvement of therapeutic effects and life quality of patients. 2016 Vol. 23 (3): 99-101 [Abstract] ( 135 ) HTML (42 KB)  PDF  (0 KB)  ( 18 ) 102 The influence of mtDNA deletion mutantion on the ototoxicity susceptibility of cisplatin LI Yu-fang;YANG Zhi-hang;YANG Yu;NI Yue-qiu;XING Ai-ping Objective To establish an animal model of mitochondrial DNA (mtDNA) deletion mutantion and to investigate the influence of mtDNA deletion mutantion on the ototoxicity susceptibility role of cisplatin.Methods Wistar rats were randomly divided into experimental group and control group，and there were 20 rats in each group.Doxorubicin (DOX) was subcutaneously injected at dose of 2 mg/kg twice per week for 3 months in experimental group.Control group was identical to experimental group，except normal saline was substituted for DOX.Cisplatin was intraperitoneally injected 2 mg/kg per day for 6 consecutive days in both groups.Auditory brainstem response (ABR) threshold was tested and 4834 bp deletion mutantion of mtDNA in inner ear membranous labyrinth for rats was tested by PCR technique.Results In experimental group，13 of the 20 rats were demonstrated 4834 bp mtDNA deletion，while control group was negative.ABR threshold was improved before and after cisplatin used in rats，and there was a statistical difference of mean between two groups (P＜0.05).Conclusion In the inner ear tissue of the rat，DOX can induce mtDNA deletion mutantion.mtDNA deletion of the inner ear tissue of the rat can increase its sensitivity of ototoxicity role of cisplatin. 2016 Vol. 23 (3): 102-104 [Abstract] ( 136 ) HTML (47 KB)  PDF  (0 KB)  ( 28 ) 105 Research of TNF-α and IL-1β expression in cerebral contusion and laceration complicated with subdural hematoma in rats HUANG Min-dong;ZOU Jian-dan Objective To explore the expression of TNF-α and IL-1β in cerebral contusion and laceration complicated with subdural hematoma in rats.Methods One hundred and twenty rats were evenly divided into normal group and model group in random.The cerebral contusion and laceration complicated with subdural hematoma model was established by rapid decompression after injecting water using sacculus.Brain tissue was taken by craniotomy at 6 h，12 h and 24 h in model group.The expression of TNF-α and IL-1β in brain tissue were detected by SP immunohistochemistry.Results The TNF-α and IL-1β expression level in brain tissue at 6 h，12 h and 24 h in model group was greatly improved respectively，while the corresponding expression level in normal group was obviously decreased respectively，and there was a statistical difference between two groups (P＜0.05).Conclusion In the model of cerebral contusion and laceration complicated with subdural hematoma，expression level of TNF-α and IL-1β is greatly increase after 6 h，12 h and 24 h trauma，and it indicates that cerebral injury or edema. 2016 Vol. 23 (3): 105-107转110 [Abstract] ( 113 ) HTML (50 KB)  PDF  (0 KB)  ( 35 ) 108 Analysis the female genital tract Mycoplasma infection status and drug resistance ZHANG Shu;XU Qi;ZHANG Li;HE Jun Objective To understand the genital tract Mycoplasma infection status and sensitivity of Mycoplasma antibacterial drugs of female patients with non-gonoccus vaginitis to guide clinical rational drug use.Methods 3902 genital tract secretions samples inspected by department of gynecology from January 2014 to December 2014 were selected.Mycoplasma isolation culture drug sensitivity kit produced by Zhuhai Deere biological engineering co.，Ltd.，was used to conduct type identification and drug sensitive test.Results The total positive infection rate of Mycoplasma was 55.1% and positive rate of Uu，Mh and mixed infection of Uu+Mh was 67.4 %，4.7% and 27.9% respectively.The drug sensitivity results showed that josamycin，minocycline and doxycycline had higher sensibility to Mycoplasma and the sensitive rate was100%，91.6% and 91.2% respectively.Ciprofloxacin had the highest drug resistance rate (82.8%) in Mycoplasma.Large ring lactone class commonly used drugs liked azithromycin，roxithromycin and clarithromycin，through had higher sensitive to simple Uu infection，they had poor antibacterial activity to Mh infection.So it should be considered when applied.Conclusion Josamycin，minocycline and doxycycline can be the empirical antibiotics for Mycoplasma infection.For different types of Mycoplasma infection，the doctors should be chose antimicrobial reasonable according to drug sensitive test report. 2016 Vol. 23 (3): 108-110 [Abstract] ( 112 ) HTML (34 KB)  PDF  (0 KB)  ( 33 ) 111 The change and affecting factors of blood lipid and glucose level in patients with subclinical thyroid dysfunction CHEN Si-mei Objective To explore the change and affecting factors of blood lipid and glucose level in patients with subclinical thyroid dysfunction.Methods 300 subclinical thyroid dysfunctional patients with TSH＜0.350 mU/L received by our hospital were set as subclinical hyperthyroidism group，75 cases with TSH＞5.500 mU/L were set as subclinical hypothyroidism group，and 300 healthy examined persons were set as healthy control group from July 2011 to June 2015，then t test was used to compare the LDL，HDL，TG，TC，and GLU level between subclinical hyperthyroidism group，subclinical hypothyroidism group and healthy control group，while Pearson analysis method was used to detect the relationship between these indictors with TSH，T4，T3，FT4，and FT3，and Logistics regression was used to analyze the affecting factors for blood lipid and glucose level.Results Compared with healthy control group，HDL level in subclinical hyperthyroidism group was significantly rised (t=2.119，P=0.034)，and TC level in subclinical hypothyroidism group was significantly rised (t=2.036，P=0.042).In subclinical hyperthyroidism group，FT3level was positively correlated with HDL level (r= 0.107，P=0.009)，while in subclinical hypothyroidism group，T4level was negatively correlated with GLU level (r=-0.104，P=0.044)，FT3level was positively correlated with HDL level (r=0.105，P=0.042)，but negatively correlated with GLU level (r=-0.113，P=0.028).Smoking history was the risk factor for abnormal TG level in patients with subclinical thyroid dysfunction (P=0.023，OR=1.547，95%CI:0.740-1.806).Conclusion Blood lipid level is abnormal in patients with subclinical thyroid dysfunction，and it is related to partly indictors of thyroid function，and smoking is a risk factor in patients with dyslipidemia. 2016 Vol. 23 (3): 111-114 [Abstract] ( 121 ) HTML (49 KB)  PDF  (0 KB)  ( 31 ) 115 Clinical value of joint detection of Cys-C and β2-MG in blood and m-Alb in urine in early diagnosis of diabetic nephropathy CHEN Shao-lin Objective To explore the clinical value of joint detection of Cys-C and β2-MG in blood and m-Alb in urine in early diagnosis of diabetic nephropathy.Methods From March 2012 to May 2014，58 patients with diabetic nephropathy admitted into our hospital were selected as research object and set as research group.Another group of 58 healthy people after physical examination in our hospital was selected as control group at the same period.The content of Cys-C，β2-MG，and m-Alb in the two groups was observed respectively.The positive rate，sensitivity，and specificity between single detection and joint detection was compared respectively.Results The content of Cys-C and β2-MG in blood and m-Alb in urine in research group was obviously higher than that of control group，and there was a statistical difference between two groups (P＜0.05).The positive detection rate of Cys-C，β2-MG in blood and m-Alb in urine was 72.4%，56.9% and 62.1% respectively in patients of research group.The positive rate of joint detection of these three indicators reached 89.7%.The positive rate and sensitivity of joint detection was obviously higher than that of any single detection，and there was a statistical difference (P＜0.05).The specificity between single detection and joint detection was basically in coincidence，and there was no statistical difference (P＞0.05).Conclusion Cys-C，β2-MG in blood，and m-Alb in urine can be considered as important indicators in early diagnosis of diabetic nephropathy.Joint detection of these three indicators has a higher clinical value，which is applicable for application and promotion in clinic. 2016 Vol. 23 (3): 115-117 [Abstract] ( 121 ) HTML (46 KB)  PDF  (0 KB)  ( 25 ) 118 Study on the correlation between quality of life and self management behavior of patients with coronary heart disease after percutaneous coronary intervention LIAO Min-yuan;WANG Ming-zhu;TANG Qun-ying Objective To analyze the correlation between the quality of life and self management behavior of patients with coronary heart disease after percutaneous coronary intervention.Methods 150 patients with CHD who received PCI for the first time in the hospital during October 2013 to October 2014 and were followed up within a year after discharge were selected as the research objects.The general information questionnaire，health status questionnaire and chronic disease self management behavior study measuring table were used to grasp the patients' general information，quality of life and self management status.The correlation between the quality of life and self management behavior of patients with CHD after PCI was analyzed.Results The overall self management of patients with CHD were in the lower-middle level.The scores of dimension management levels from high to low were medical management of disease，daily life management and emotional management，successively.The lowest dimension of quality of life score in patients with CHD was emotional function while the highest was physiological function.The quality of life SF-36 dimension of patients with CHD and each dimension of self management behavior were positively related（r=0.132～0.417）.Conclusion High-level self management behavior can promote the quality of life of patients after PCI. 2016 Vol. 23 (3): 118-120 [Abstract] ( 138 ) HTML (40 KB)  PDF  (0 KB)  ( 40 ) 121 Discussion on safety management of hospital information system WANG Lei With the rapid development of hospital information，information system security has been promoted to an unprecedented height.In recent years，the author has been engaged in the hospital information system security management work，accumulated some work experience.This paper analyzes the existing problems in the current safety management.In this paper，from two aspects of safety technology and safety management to illustrate how to do a good job of safety management，better to ensure the safety of medical order and medical data. 2016 Vol. 23 (3): 121-124 [Abstract] ( 111 ) HTML (51 KB)  PDF  (0 KB)  ( 40 ) 125 Effect value of group management pattern in diabetes health management HUANG Ying-hua;CHEN Xue-yun;HU Gui-fang Objective To explore the role of group management pattern in diabetes health management.Methods 300 type 2 diabetes mellitus of our hospital were selected.Patients were randomly divided into intervention group and control group.arious index of diabetes mellitus were observed and compared.Results The awareness of diabetes mellitus in intervention group obvious increased than that of control group (P＜0.01)；In the respect of healthy body various index measurement improvement，the intervention group was better than that of control group，with significant difference (P＜0.01).Conclusion Applying group management pattern to diabetes health management can help patients better to understand the disease，control blood glucose，change the bad behavior and provide reference and basis for diabetes health management. 2016 Vol. 23 (3): 125-127 [Abstract] ( 152 ) HTML (40 KB)  PDF  (0 KB)  ( 34 ) 128 Application effect of dynamic management in more nursing unit human resources YANG Xiu-ling Objective To explore the dynamic management of more nursing unit nursing human resources to make full use of human resources，enhance nursing quality and patients' satisfaction.Methods From January 2013 to December，departments that used traditional personnel allocation method to manage ward nursing were selected as control group；from January 2014 to December，departments that used dynamic management method to manage ward nursing were selected as observation group.Nursing quality liked nursing record，classification nursing，healthy education，ward management and patient satisfaction were analyzed retrospectively，and the application effects of human resources in two groups were compared.Results It maked full use of human resources after conducting human resources dynamic management.The nursing record score was increased to (97.87±2.23) points，classification nursing score was increased to（97.81± 3.42）points，healthy education score increased to (97.02±2.33) points，ward management score was increased to（99.36± 2.97）points and patient satisfaction was increased to (97.12±3.88) points.Apart from healthy education，all of the others had statistical significance (P＜0.01).Conclusion Conducting human resources dynamic management can make full use of human resources，improve the work efficiency maximum and enhance nursing quality and patient satisfaction. 2016 Vol. 23 (3): 128-130 [Abstract] ( 107 ) HTML (45 KB)  PDF  (0 KB)  ( 39 ) 131 Problem and countermeasure of occupational disease prevention and control work SUN Yong-xin;GUO Jun At present，China's industrialization and urbanization have developed rapidly，but the work of prevention and control of occupational disease is also very serious，which is not consistent with the rapid development of our country's economic level，occupational disease has become a major public health and social problems in China.This paper analyzes the current situation of occupational disease prevention and control in China，and put forward some suggestions and countermeasures for the problems，hope to provide help for the comprehensive development of occupational disease prevention and control work. 2016 Vol. 23 (3): 131-133 [Abstract] ( 128 ) HTML (43 KB)  PDF  (0 KB)  ( 33 ) 134 Application effect of infection control intervention in the control of multidrug-resistant bacteria with hospital infection MA Shi-hong Objective To explore the application effect of infection control intervention in the control of multidrugresistant bacteria with hospital infection.Methods 1000 cases of multidrug-resistant bacteria infection from January 2010 to June 2014 in our hospital were selected and randomly divided into the observation group and the control group.The observation group was given infection control intervention of multidrug-resistant bacteria，the control group was implemented with conventional treatment.The inspection rate of bacterial culture，the qualified rate of hand hygiene，the timely isolation rate in the two group was recorded，and the infection rate of different parts in the two groups was compared.Results The inspection rate of bacterial culture，the qualified rate of hand hygiene，the timely isolation rate in the observation group was higher than that in the control group，with significant difference (P＜0.05).The inspection rate of urinary system and blood system in the observation group was lower than that in the control group，with significant difference (P＜0.05).The total inspection rate in the observation group was lower than that in the control group，with significant difference (P＜0.05).Conclusion Effective infection control intervention in hospital infection has positive implication to prevent and reduce multidrug-resistant. 2016 Vol. 23 (3): 134-136 [Abstract] ( 99 ) HTML (39 KB)  PDF  (0 KB)  ( 38 ) 137 Effect of electronic standardized patients in the clinical practice teaching of traditional Chinese medicine college and university ZHAO Xian-min;ZHANG Li-ping;LI Nan;LIU Yong;ZHANG Ming-hao;ZHU Yan-qin This article discusses the effect of electronic standardized patients (ESP) in the medical clinical practice teaching of traditional Chinese medicine (TCM) college and university through analyzing advantages and disadvantages of the ESP，and puts forward some meliorative advice such as increasing the joint of student standardized patients and ESP，increasing ESP in the TCM college and university，changing thoughts and concept，strengthening the early clinical practice education of medical students. 2016 Vol. 23 (3): 137-140 [Abstract] ( 111 ) HTML (47 KB)  PDF  (0 KB)  ( 35 ) 141 Practice and exploration on the construction of ophthalmology elaborate course WANG Rui The construction of elaborate course is the major measure of college course reform and construction，and also the important reflection of professionals training model.This article describes forming of the excellent teaching team，teaching reform and building quality control system etc.in the process of the construction of ophthalmology elaborate course in Changchun Medical College in order to form the vertical course features of the length，width and height.The construction of elaborate course can improve the teachers'teaching level and play a promoting role in training applied talents with solid foundation of ophthalmology eye optical technology. 2016 Vol. 23 (3): 141-143 [Abstract] ( 102 ) HTML (38 KB)  PDF  (0 KB)  ( 34 ) 144 Discussion about teaching method reform of human anatomy HE Zu-jiang;WANG Xiang-jun As one of essential elements of medical professional teaching，human anatomy is a required course of all medical educational majors.With rapid development of modern medical technology，requirement for medical students is growing，which leads to a substantial increase in the amount of information within the limited classroom time，and knowledge that students need to master increases accordingly.Defect of traditional anatomy teaching methods exist，so that it cannot meet needs of modern educational development and social development.Anatomy teaching methods need to be reformed with the progress of society and the development of higher education.This paper discusses the teaching methods of human anatomy reform measure from how to improve effectiveness of human anatomy teaching and to motivate initiative of students and to discuss reform measures of anatomy teaching methods by combining with micro-class，PBL，case study and other teaching ways，so that medical students entered the medical school in the first time can learn anatomy well easily，seriously and rigorously，improve teaching quality，lay a good foundation for the latter part of medical education. 2016 Vol. 23 (3): 144-146 [Abstract] ( 94 ) HTML (48 KB)  PDF  (0 KB)  ( 33 ) 147 Preliminary exploration of personnel training mode of combination traditional Chinese medicine with western medicine LI Sheng;CHEN Xiao-fang;LIN Zheng-wen;CHEN Liang;CHEN Zhu-qin;CHEN Xi;YAN Zi-xing;ZHENG Xue-feng At present，the cooperation train of Chinese and western medicine is still in the exploratory stage.In this paper，through the analysis of the problem and puzzle in teaching practice of combination Chinese and western medicine，solution strategy is proposed，such as enhancing learning interest and awareness of students，improvement teaching methods，increasing practical skills training，combination teaching and research and reforming examination and examination mode to reform the teaching mode of Chinese and western medicine，optimizing teaching plan，in order to form a new and practical personnel training mode of combination traditional Chinese medicine with western medicine. 2016 Vol. 23 (3): 147-150 [Abstract] ( 128 ) HTML (46 KB)  PDF  (0 KB)  ( 29 ) 151 Effect observation of high quality nursing applied to surgical operation on outpatients LI Rui-yi;FENG Mei-juan;LUO Li-li Objective To investigate the clinical effect of high quality nursing applied to surgical operation on outpatients.Methods 50 patients in surgical operation on outpatients from in November 2013 to July 2014 after the implementation of the quality of nursing service were chose as the observation group，from January 2013 to October before implementation of the quality of nursing service 50 cases were chose as control group.The control group were given conventional nursing，and observation group were given high quality nursing.The two groups were observed in the blood pressure change.The pain of patients were observed by VAS.The negative emotions of patients were investigated with the Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS).The satisfaction of nursing service in two groups were observed by way of questionnaire survey.Results After the high quality nursing service，DBP and SBP preoperative and intraoperative of patients in the observation group were significantly lower than control group(P＜0.05)，The scores of SAS and SDS after nursing of the observation group were significantly lower than those of the control group (P＜0.05)，The scores of VAS in the control group were significantly higher than that of the observation group (P＜0.05)，The satisfaction rate of observation group was 98.0%，was significantly higher than that(84.0%) control group (P＜0.05).Conclusion High quality nursing can promote the work of outpatient surgical nursing，improve negative emotions of patients，further improve the quality of outpatient surgical nursing.It not only can improve the psychological status of patients，also can ease the pain of patients，and improve the satisfaction of patients. 2016 Vol. 23 (3): 151-153转156 [Abstract] ( 111 ) HTML (47 KB)  PDF  (0 KB)  ( 34 ) 154 Influence of psychological nursing intervention before anesthetization on emergence agitation by general anesthesia GUO Xiao-jun;XU You-fang Objective To observe the influence of psychological nursing intervention before anesthetization on emergence agitation (EA) by general anesthesia，and to provide reference for surgical patients through the recovery period of general anesthesia.Methods 120 patients with laparoscopic hysterectomy and general anesthesia in our hospital from September to December in 2014 were selected.They were randomly divided into control group and observation group，with 60 cases in each group.In the control group，conventional nursing before surgery was applied，while in the observation group，on the basis of the conventional nursing，psychological nursing intervention before anesthetization was provided.The blood pressure，heart rate and emergence agitation in the two groups was observed during general anesthesia.Results The blood pressure，heart rate and restlessness during recovery in observation group was lower than the control group，the difference between two groups was significant (P＜0.05).Conclusion Psychological nursing intervention before anesthesia can effectively alleviate the occurrence of EA，and anesthesia surgery patients' blood pressure and heart rate are more stable when awakening，which is worthy of clinical reference and promotion. 2016 Vol. 23 (3): 154-156 [Abstract] ( 116 ) HTML (39 KB)  PDF  (0 KB)  ( 34 ) 157 Application effect of comprehensive nursing intervention in the nursing of infantile diarrhea QIU Hai-yan Objective To explore the application effect of comprehensive nursing intervention in the nursing of infantile diarrhea.Methods 92 infantile patients with diarrhea admitted into our hospital from March 2013 to March 2015 were selected and randomly divided to the observation group and the control group，with 46 cases in each group.The control group was given regular nursing intervention，and the observation group was given comprehensive nursing intervention.The nursing effect between the two groups was compared.Results The total effective rate in the observation group was 95.7%，which was higher than 76.1% of control group，the difference between two groups was statistically significant (P＜0.05).The recovery time of diarrhea，length of stay in observation group was shorter than the control group，and medical expenses in the observation group was less than the control group，the difference between the two groups was statistically significant(P＜0.05).Conclusion Comprehensive nursing intervention in the treatment of infantile diarrhea can significantly improve the clinical efficiency，and promote the recovery of children in a timely manner. 2016 Vol. 23 (3): 157-158转161 [Abstract] ( 111 ) HTML (38 KB)  PDF  (0 KB)  ( 38 ) 159 Application effect of clinical nursing pathway on the children with bronchial asthma LI Ling Objective To study the application effect of clinical nursing pathway on the children with bronchial asthma.Methods 92 children with bronchial asthma in our hospital from February 2014 and March 2015 were selected and randomly divided into study group and control group，with 46 cases in each group.The control group was given conventional nursing intervention，while the study group was given personal nursing intervention on the basic of the clinical nursing pathway strictly.The quality of life，hospitalization days，hospitalization expenses，health knowledge score，treatment compliance，nursing satisfaction in two groups was observed after the nursing intervention.Results The quality of life score in two groups was significantly higher than that of before admission（P＜0.05），and quality of life score in study group was higher than that of control group（P＜0.05）.The hospitalization days in study group was significantly shorter than the control group，the hospitalization expense was significantly lower than the control group，and the guardian health education score was higher than the control group，the differences between two groups were significant (P＜0.05).The treatment compliance and nursing satisfaction in study group was significantly higher than the control group (P＜0.05).Conclusion The clinical nursing pathway for nursing in children with bronchial asthma can significantly shorten the hospital stay，improve the nursing satisfaction and the quality of life after the intervention.It is worth extending in clinical. 2016 Vol. 23 (3): 159-161 [Abstract] ( 160 ) HTML (43 KB)  PDF  (0 KB)  ( 30 ) 162 Application effect of humanistic care in endoscopic examination of E.N.T. MO Cai-yin;GUAN Cai-ju;OUYANG Shao-ji Objective To study the application effect of humanistic care in endoscopic examination of E.N.T..Methods 154 cases of patients with endoscopic examination of E.N.T.in our hospital from February 2013 to June 2014 were selected and randomly divided into control group and experimental group，each group had 77 cases.The control group was given routine nursing，while the experimental group was given humanistic care nursing on the basis of routine nursing.Emotion status and nursing satisfaction in two groups were observed.Results The incidence of adverse emotional in experimental group was 32.5%　(25/77)，which was lower than 80.5%(62/77) of control group，and the difference was statistical significance (P＜0.05).The nursing satisfaction in experimental group was 96.1%(74/77)，which was higher than 64.9%(50/77) of control group，and the difference was statistical significance (P＜0.05).Conclusion During endoscopic examination of E.N.T.，using humanistic care nursing can obvious enhance patient's satisfaction with the hospital service，remission the relationship between doctors and patients.It is worthy of clinical popularization and Application. 2016 Vol. 23 (3): 162-163转166 [Abstract] ( 120 ) HTML (40 KB)  PDF  (0 KB)  ( 38 ) 164 Impact of mental nursing on nerve function recovery of patients with acute ischemic stroke LIU Jing-jing Objective To explore the impact of mental nursing on nerve function recovery of patients with acute ischemic，and to provide thinking for clinical nursing work in the future.Methods 100 patients with acute ischemic stroke admitted into neurology department of our hospital from January to December in 2014 were selected.They were divided into control group (n=50) and observation group (n=50) by using random sampling method.The control group was given routine nursing，and observation group was conducted mental nursing on the basis of routine nursing.The neurologic deficits in two groups was evaluated by the National Institute of Health stroke scale (NIHSS) at admission，1 week and 4 weeks after admission，and therapy effects was compared.Results The NIHSS score had no difference between two groups at admission (P＞0.05).1 week and 4 weeks after admission，the NIHSS score in observation group was respectively (7.39±1.51) and (3.53±1.61) points，which was significantly decreased compared with the time of admission，and the NIHSS score in observation group was lower than that of the control group，the difference was statistical significance (P＜0.05).The total effective rate in observation group was 92%，which was higher than 80% of control group (P＜0.05).Conclusion Mental nursing can obvious improve the nerve function of patients with acute ischemic stroke，and improve the treatment effect，promote the rehabilitation for patients. 2016 Vol. 23 (3): 164-166 [Abstract] ( 99 ) HTML (39 KB)  PDF  (0 KB)  ( 39 ) 167 Influence of humanized nursing intervention on patients with severe hemorrhagic shock FENG Ying-qing Objective To explore the influence of humanized nursing intervention on patients with severe hemorrhagic shock.Methods 200 patients with severe hemorrhagic shock admitted into our hospital from January 2011 to January 2014 were selected and randomly divided into control group and observation group，with 100 cases in each group.In control group，conventional nursing was used，while in observation group，humanized nursing intervention was applied.The rescue success rate，blood loss，satisfaction with doctors and nurses，quality of life in two groups were compared.Results There was no significant difference between the two groups of the success rate and blood loss (P＞0.05).The satisfaction with doctors and nurses in observation group was higher than the control group，the difference was significant(P＜0.05).There was no significant difference in two groups in quality of life score before nursing (P＞0.05).After nursing，the quality of life score in two groups was improved，and quality of life score in observation group was higher than the control group，the difference was significant (P＜0.05).Conclusion Humanized nursing intervention can quickly reverse the symptoms in patients with severe hemorrhagic shock，prevent adverse reactions，ensure successful treatment and smooth discharge from hospital，and improve satisfaction and quality of life. 2016 Vol. 23 (3): 167-169 [Abstract] ( 116 ) HTML (45 KB)  PDF  (0 KB)  ( 34 ) 170 Traditional Chinese medical nursing intervention in community elderly constipation LI Qiu-hong;GU Yan-ping;HE Su-hong Objective To explore the effect of traditional Chinese medical nursing intervention in community elderly constipation.Methods 100 cases of elderly patients with constipation treated in our center from June 2014 to May 2015 were selected and randomly divided into experimental group and control group，50 cases in each group.The control group was given routine nursing，the experimental group was given traditional Chinese medical nursingtechnology liked acupressure，acupuncture and diet regulation on the basis of routine nursing.Nursing effect，nursing satisfaction and relapse status in two groups was observed.Results The total effective rate in control group was 52%，total satisfaction was 38%，and relapse rate was 86%.The total effective rate in experimental group was 96%，total satisfaction was 96%，and relapse rate was 12%.The differences between two groups were statistical significance (P＜0.01).Conclusion Traditional Chinese medical nursing intervention can effectively alleviate the symptorn in elderly patients with constipation，enhance therapy satisfaction and has better late result. 2016 Vol. 23 (3): 170-172 [Abstract] ( 106 ) HTML (44 KB)  PDF  (0 KB)  ( 37 ) 173 Value effect study of risk management in the application of dental implantation nursing REN Xiao-yun Objective To explore the value effect of risk management in the application of dental implantation nursing.Methods 120 patients who conducted dental implantation in Shaoguan stomatological hospital from January 2014 to January 2015 were selected.Patients were randomly divided into control group and observation group.Patients in control group were treated with routine nursing and patients in observation group were used risk management intervention method.Value effect contained incidence rate of risk events，patient satisfaction and service quality were compared between two groups.Results The incidence rate of risk hazards in observation group was obvious lower than that of control group.The patient satisfaction was 85% in observation group，obvious higher than that was 21.67% in control group （X2=48.35，P＜0.05）.The value of nursing quality in observation group was (81.5±0.2)，higher than that was (60.1±0.3) in control group.the difference statistical significance (t=111.67，P＜0.05).Conclusion Conducting risk management during the nursing of dental implantation operation is helpful to reduce the incidence rate of risk hazards，enhance nursing quality and improve the relationship between doctors and patients. 2016 Vol. 23 (3): 173-175 [Abstract] ( 132 ) HTML (41 KB)  PDF  (0 KB)  ( 29 ) 176 Effect analysis of nursing cooperated in flexible ureteroscope and holmium laser in the treatment of kidney stone HUANG Ming-jun;LI Ming-zhu;LIU Ting Objective To explore application of high quality nursing and its clinical effect after kidney stone treated by flexible ureteroscope and holmium laser.Methods From April 2013 to January 2015，135 patients with kidney stones by surgical treatment in our hospital were selected.According to a random number table，they were divided into nursing group（n=78）and control group（n=77）.The clinical conditions by different nursing methods were compared.The occurrence of patients' complications and nursing satisfaction were recorded by medical staff in order to compared and explain the clinical effect by high quality nursing after surgery.Results In the nursing group，there was inflammation in 3 cases，inappropriate pressure control in 1 case，and residual calculi in 1 case.In the control group，the number of inflammation，inappropriate pressure control，and residual calculi was 15，7，and 6.After comparison，the occurrence of complications in the nursing group was greatly lower than that of control group（X2=20.75，P=0.000）.In the nursing group，the number of extreme satisfaction，satisfaction，and dissatisfaction was 45，30，and 3 in turn，and the rate of satisfaction was 96.2%.In the control group，they were 21，29，and 27 respectively，and the rate of satisfaction was 64.9%.After comparison，the rate of satisfaction in the nursing group was superior than that of control group（X2=24.19，P=0.000）.Conclusion Surgical high quality nursing can effectively improve the clinical effect of kidney stone treated by flexible ureteroscope and holmium laser as well as increase patient's satisfaction. 2016 Vol. 23 (3): 176-178 [Abstract] ( 126 ) HTML (43 KB)  PDF  (0 KB)  ( 33 ) 179 Application research of nursing intervention in improving the quality of life of elderly patients with hypertension in community WEI Xiao-min Objective To explore the effect of community nursing intervention on quality of life in elderly patients with hypertension.Methods 113 elderly patients with hypertension in our community from December 2013 to March 2015 were selected as research object.The health record card was established for patients，and community nursing intervention such as health education，psychological counseling，diet，exercise and behavior guidance，medication guidance were used for a period of 2 months.The awareness rate of hypertensive disease，compliance rate，blood pressure control rate and the grade of life quality evaluation questionnaire were compared before and after intervention.Results After intervention，the awareness rate of hypertensive disease，compliance rate，blood pressure control rate and the grade of life quality evaluation questionnaire in patients was significantly higher than before intervention，and the difference was significant (P＜0.05).Conclusion Community nursing intervention can effectively increase the treatment effect of elderly patients with hypertension，improve the clinical symptoms and the quality of life. 2016 Vol. 23 (3): 179-181转184 [Abstract] ( 132 ) HTML (44 KB)  PDF  (0 KB)  ( 35 ) 182 Impact of early nursing intervention on prognosis of neonatal hypoxic ischemic encephalopathy WEI Juan-juan Objective To explore the impact of early nursing intervention on prognosis of neonatal hypoxic ischemic encephalopathy.Methods 90 neonatal hypoxic ischemic encephalopathy from April 2012 to November 2014 of our hospital were selected as study object.Patients were divided into control group and study group according to the admission number，and each group was 45 cases.Patients in two groups were given different nursing mode，patients in control group were given routine nursing and patients in study group were given early nursing intervention.Clinical condition of two groups were compared.Results After nursing for 6 months，exercise and mental development index in study group were better than that of control group，and the difference was statistical significance (P＜0.05).The DQ after nursing in study group was better than that of control group，and the difference was statistical significance (P＜0.05).Conclusion Early nursing interventioncan use for neonatal hypoxic ischemic encephalopathy and can well control sign and clinical symptom of neonatal，improve the prognosis of neonatal and enhance survival rate.It has great clinical application value. 2016 Vol. 23 (3): 182-184 [Abstract] ( 101 ) HTML (40 KB)  PDF  (0 KB)  ( 35 ) 185 Impact of dietary intervention on esophageal and variceal bleeding patients with cirrhosis ZHANG Gui-juan;WANG Jin-hua;YANG Shuang;WANG Li-li Objective To explore the effects of esophageal varices patients with dietary intervention on gastrointestinal bleeding.Methods 90 patients with cirrhosis complicated by esophageal and gastric varices bleeding from January 2011 to June 2013 of our department were selected，and were divided into contrast group (n=45) and intervention group (n=45) according to hospital chronologically.The contrast group was cared by conventional methods.The intervention group was on the basis of the active treatment original disease.From the enter hospital assessment，one guidance，dietary intervention，self-management，and other aspects of comprehensive follow-up of institutionalized dietary intervention.The initial bleeding rebleeding rate and mortality between two group was compared.Results The initial bleeding rate of the patients in intervention group was 28.9%，which was lower than that of the contrast group，which rate was 33.3%，there was no significant difference between two groups (P＞0.05).The bleeding rate of the intervention group was 31.1%，which was significantly lower than 64.4% in the control group，with significant difference (P＜0.05).The death rate of intervention group was 4.4%，lower than 15.6% in the control group，with significant difference (P＜0.05).Conclusion The patients of esophageal varices with cirrhosis，primary disease need a timely standard treatment，and a reasonable diet intervention，which can prevent rebleeding in patients and reduce mortality. 2016 Vol. 23 (3): 185-188 [Abstract] ( 127 ) HTML (53 KB)  PDF  (0 KB)  ( 35 ) 189 Application effect of targeted nursing in the elderly patients with hypertension BAO Feng-juan Objective To explore the application effect of targeted nursing in the elderly patients with hypertension.Methods 100 elderly patients with hypertension in our hospital from February 2013 to February 2015 were selected and randomly divided into observation group and control group，with 50 cases in each group.The control group was received routine nursing care.The observation group was given the targeted nursing.The changes of blood pressure in the two groups was observed before and after nursing，and the incidence of hypertension complications，quality of life score in the two groups was recorded.Results After intervention，the blood pressure in two groups was decreased，and the blood pressure in observation group was lower than that of the control group，the difference was statistically significant (P＜0.05).The incidence of cerebral hemorrhage，cerebral infarction，angina，myocardial infarction and renal injury in observation group were lower than those of control group，the differences were statistically significant (P＜0.05).The quality of life score in observation group was higher than that of control group，the difference was statistically significant (P＜0.05).Conclusion The targeted nursing can help to control the blood pressure in elderly patients with hypertension，which can reduce the complications and improve the quality of life.Its nursing effect is remarkable. 2016 Vol. 23 (3): 189-191 [Abstract] ( 106 ) HTML (42 KB)  PDF  (0 KB)  ( 41 ) 192 Influence of comprehensive nursing intervention in patients with tuberculous pleurisy FENG Xiao-ying;LU Jie Objective To explore the influence of nursing intervention on treatment compliance and therapeutic effect in patients with tuberculous pleurisy.Methods 96 patients with tuberculous pleurisy treated in our hospital February 2013 to August 2014 were selected and randomly divided into observation group and control group，with 48 cases in each group.In the control group，conventional nursing was used，while in the observation group，comprehensive nursing intervention was adopted.The treatment compliance and therapeutic effect in two groups was compared.Results After nursing intervention，the treatment compliance and clinical efficacy in the observation group were higher than those in the control group with statistical differences (P＜0.05).Conclusion Comprehensive nursing intervention can greatly improve treatment compliance and therapeutic effect in patients with tuberculous pleurisy，decrease the recurrence and drug resistance，and better patient's prognosis. 2016 Vol. 23 (3): 192-194 [Abstract] ( 121 ) HTML (45 KB)  PDF  (0 KB)  ( 32 ) 195 Effect of psychological nursing in bad mood and nursing satisfaction on the patients with induced abortion with scar uterus in lactation CAI Li-na Objective To investigate the effect of psychological nursing care in bad mood and nursing satisfaction on the patients with induced abortion with scar uterus in lactation.Methods 120 patients with induced abortion with scar uterus in lactation from January 2014 to June 2015 were randomly divided into observation group and control group，60 cases in each group.The control group received routine nursing care.The observation group used psychological nursing intervention on the base of the control group.The bad mood of the two groups of patients was evaluated by anxiety self rating anxiety scale (SAS) and self rating depression scale (SDS).Results There was no significant difference in SAS and SDS scores between the two groups (P＞0.05).The SAS and SDS scores in the observation group were significantly lower than those in the control group (P＜0.05).The nursing satisfaction of the observation group was 95.00%，it was significantly higher than that of the control group (75.00%) (P＜0.05).The operation time of the observation group was (6.83±1.54) min，it was significantly lower than that of the control group (7.78±1.67) min (P＜0.05).There was no difference between the two groups of the incidence of abortion syndrome (P＞0.05).Conclusion The nursing intervention measures for the patients with painless induced abortion in uterine scar can effectively reduce the anxiety and depression of patients，improve nursing satisfaction.It is worthy of extensive promotion in clinical practice. 2016 Vol. 23 (3): 195-197 [Abstract] ( 132 ) HTML (43 KB)  PDF  (0 KB)  ( 34 )

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