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Quick Search     Adv Search 2016 Vol. 23, No. 33 Published: 2016-11-28   4 Study standard app lication ofβ-lactam antibiotics to reduce AUD by PDCA YANG Jiang-de;XU Ting-lan;YANG Shao-lin;LIU Yong-hua;XU Jing ObjectiveTo explore the measures in the management of antibiotic use density（AUD）.MethodsPDCA （plan,do,check,action）management cycle was introduced in AUD management,formulate managenentmeasunes by the investigation and analysis of the cause,such as target searches after the correct processing aud final evaluation results.ResultsThrough the implementation of PDCA cyclemethod,the reject ratio use ofβ-lactam antibiotics had a distinct improvement in treatment，typeⅠincision antibiotic prevention use,dischargemedication were compared,the differences were siginificant(P<0.05).The antibiotic use density(AUD)tended to bemuch lower(P<0.05).ConclusionPDCA management cycle is effective for the rational use ofβ-lactam antibiotics and the reduction of AUD. 2016 Vol. 23 (33): 4-07 [Abstract] ( 160 ) HTML (58 KB)  PDF  (0 KB)  ( 29 ) 8 The quantity analysis of qingrekaiyin teabag(Ⅱ)by UV and FTIR LIJiang;ZHANG Ya-nan ObjectiveTo analysis the quality of qingrekaiyin teabag(Ⅱ).MethodsThe quality of four batches of samples and a group of control sample of qingrekaiyin teabag(Ⅱ)was analyzed by the method of ultraviolet spectroscopy (UV)and fourier transform infrared spectroscopy (FTIR).ResultsUV showed that the maximum deviation of UV absorption peaks were 1.6,1.8 and 0.8 in three kinds of solvents (distilled water,95%ethanol and petroleum ether).The position of themaximum absorption peakswere basically consistent of four batches of samples and the control sample,and there were no significant difference.The infrared spectrum and infrared first derivative spectra were similar in shape of four batches of samples and the control sample.There were 7 common characteristic peaks of infrared spectrum,in 3353 cm-1,2926 cm-1,1632 cm-1,1418 cm-1,1035 cm-1,777 cm-1,613 cm-1respectively.There were 12 common characteristic peaksof infrared firstderivative spectra,in 2926 cm-1,2853 cm-1,1741 cm-1,1514 cm-1,1464 cm-1, 1161 cm-1,1107 cm-1,1081 cm-1,1031 cm-1,991 cm-1,777 cm-1,610 cm-1respectively.ConclusionUV is used to evaluate the quality of the samples accurately,according to absorption degree(A);FTIR can be used to measure out the differences between the composition of the sample.Both methods had strong specificity,good reproducibility,high sensitivity,and can be used to analysis the quality of qingrekaiyin teabag(Ⅱ). 2016 Vol. 23 (33): 8-10转30 [Abstract] ( 164 ) HTML (51 KB)  PDF  (0 KB)  ( 31 ) 11 Advances in imaging diagnosis of acute cerebral infarction in super acute stage GUO Jiang-yuan;WANG Bao-jun;GUO Ai-ting Cerebral infarction is a common and frequently occurring disease.It is very important to diagnose the disease in early stage.In this paper,research progress of inspection method of several common imaging are discussed,using CT plus MRI or MRI-DWI plus PWI combined with imaging methods,not only is simple,easy to accept patients,but also can improve the diagnostic accuracy,accuracy of diagnosis,accurate treatment purposes. 2016 Vol. 23 (33): 11-15 [Abstract] ( 141 ) HTML (59 KB)  PDF  (0 KB)  ( 32 ) 16 Research progress of m TOR signal pathway effect in ischem ic heart disease YANG Zi-jian;QIN Fu-zhong The increase in themorbidity and mortality of ischemic heart disease（IHD）is a serious threat to the health ofmankind.Mammalian target of rapamycin(mTOR)is a kind of conservative serine/threonine protein kinase,which can regulate the cell size,cell growth,protein synthesis,cytoskeleton,nutrition and energy transfer.Research have shown that mTOR plays a key regulating role in the occur and process of ischemic heart disease.This articlemainly discuss the role of mTOR in ischemia-reperfusion,myocardial infarction myocardial remodeling and ischemic heart failure. Furthermore，combining with the development of the mTOR inhibitors-rapamycinto to explore its clinical application prospect. 2016 Vol. 23 (33): 16-19 [Abstract] ( 203 ) HTML (45 KB)  PDF  (0 KB)  ( 38 ) 20 Effect observation of continuous negative pressure drainage in the treatment of large amount of subcutaneous effusion in the incision ZHONG Yong-fu;LI Ying;XIAOMing-gen;WANG Xiao-lan ObjectiveTo discuss the clinical effect of continuous negative pressure drainage in the treatment of large amount of subcutaneous effusion in the incision.MethodsFrom May 2010 to May 2016,36 patients with subcutaneous infection empyema or other reasons causing simple large effusion were divided into negative pressure ball group(n=15) and open dressing group(n=21)according to different incision treatmentmethods in our hospital.Patients in the negative pressure ball group were taken continuous negative pressure drainage treatment and in the open dressing group were used traditionalmethods of open drainage dressing treatment，healing time,dressing change times and scarwidth of two groupswere compared.ResultsTime from the negative pressure ball drainage treatment to extubation in the negative pressure ball group was 7-12 d,the average length of stay was 9 d;2-4 times of dressing change in each case;all wound healing were linear scar.Time of wound healing in the open dressing group ranged from 15 to 25 d,the average length of stay was 15 d;9 to 26 times of dressing change in each case,with an average of 15 times.Dressing change times in the negative pressure ball group was significantly less than that in the open dressing group,healing time and scar width was significantly better than that in the open dressing group,and the difference was statistically significant (P<0.05).ConclusionNegative pressure ball group are effective in shortening time of healing,reducing times of dressing change,easing pain of patients,decreasing workload of doctors,healing with litter scar and beautiful appearance,so it is worthy of clinical application. 2016 Vol. 23 (33): 20-22 [Abstract] ( 183 ) HTML (37 KB)  PDF  (0 KB)  ( 25 ) 23 Effect of fatty liver on the efficacy of HBeAg positive chronic hepatitis B patients WANG Yan-ling;ZHANG Bing;LIBing-qing;HE Pei-yuan;SHIJun-li;WANG Lei ObjectiveTo investigate the impact of fatty liver on antiviral efficacy of Adefovir dipivoxil and the HBsAg′s predictive value in chronic hepatitis B(CHB)patientswith e antigen(HBeAg)positive.Methods71 CHB patientswith HBeAg positive in the hospital outpatient clinic from January 2012 to December 2014 were selected as study subjects,among which,40 cases were simple hepatitis B group,31 cases of hepatitis B with nonalcoholic fatty liver disease (NAFID)were hepatitis B with fatty liver group.Patients of two groups were given oral Adefovir dipivoxil 10 mg/d antiviral therapy for 24 weeks and 36 weeks,negative conversion rate(complete virological response)of HBV-DNA in two groups were observed.According to whether or not to obtain a viral response,simple hepatitis B group and hepatitis B with fatty liver group were divided into complete viral response group and non response group,the change trends of HBV-DNA and HBsAg of two subgroups in two groupswere respectively observed in the treatment process.ResultsAfter treatment for 24 weeks and 36 weeks,HBV-DNA negative conversion rate in the hepatitis B with fatty liver group was 48.4%and 61.3%respectively,significantly lower than 75.0%，82.5%in the simple hepatitis B group,and the difference was statistically significant(P<0.05).In the simple hepatitis B group,HBsAg level of two subgroups after treatment for 24 weeks and 36 weeks was gradually decreased with HBV-DNA level,serum HBV-DNA and HBsAg values after treatment for 24 weeks and 36 weeks in the complete viral response group was significantly lower that in non response group,and the difference was statistically significant(P<0.01).In the hepatitis B with fatty liver group,HBV-DNA level of two subgroups patients after treatment for 24 weeks and 36 weeks decreased significantly,and the difference was statistically significant(P<0.01);HBsAg level during treatment in the hepatitis B with fatty liver group was decreasing,but complete viral response group compared with the non response group after treatment for 24 weeks and 36 weeks,there was no statistically significant difference (P>0.05).Conclusion HBV-DNA negative conversion rate in patientswith hepatitis B can be influenced by complicated with fatty liver;hepatitis B complicated with fatty liver,the change of HBsAg value can not reflect the situation of viral response after treatment. 2016 Vol. 23 (33): 23-26 [Abstract] ( 165 ) HTML (44 KB)  PDF  (0 KB)  ( 39 ) 27 Effect of M ontelukast combined with Salmeterol Fluticasone on the expression of cytokines related to Th17 cells in patientswith bronchialasthma FENG Xiu-li;DING Chang-jun ObjectiveTo observe effect of oral Montelukast combined with Salmeterol Fluticasone inhalation on experssion levels of cytokines related to T helper(Th)17 cells transforming growth factor beta(TGF-beta),interleukin(IL)-17 and IL-23 in patients with new-onset bronchial asthma.MethodsAccording to different treatmentmethods，sixty patientwith new-onset bronchial asthma admitted into our hospital from October 2014 to April 2016 were divided into routine treatment group(n=20)and Montelukast combined with Salmeterol Fluticasone group whom received Montelukast combined with Salmeterol Fluticasone (n=40).Another 20 health people were selected as healthy group.The serum and sputum supernatan levels of inflammatory factors such as TGF-β,IL-17 and IL-23 were measured by ELISA before and after outpatient treatment for 3 months.ResultsCompared with healthy group,the serum and sputum supernatan levels of inflammatory factors such as TGF-β,IL-17 and IL-23 was higher that in the routine treatment group and the Montelukast combined with Salmeterol Fluticasone group,and the difference was statistically significant(P<0.01).After treatment for 3 months,the expression level TGF-βand IL-23 of two groups was significantly lower than that before treatment(P<0.05);compared with routine treatment group,expression levels of serum TGF-βand IL-23 in the Montelukast combined with Salmeterol Fluticasone group decreased significantly (P<0.05).There was no significant change in the expression of IL-17 in the serum and sputum supernatant of two groups before and after treatment for 3 months (P>0.05).ConclusionCytokines related cytokines Th17 cellsmay play important roles in the development of asthma,and using of Montelukast combined with Salmeterol Fluticasone can inhibit the experssion of cytokines related to Th17 in patientswith asthma. 2016 Vol. 23 (33): 27-30 [Abstract] ( 155 ) HTML (39 KB)  PDF  (0 KB)  ( 44 ) 31 Application research of reduced glutathione combined with antiinflammatory analgesic mixture in the treatment of acute radiation esophagitis LIJing-xia;MU Shuang-feng;WANG Xiao-hong;MU Li-xiang ObjectiveTo observe effect of reduced glutathione combined with anti-inflammatory analgesic mixture in the prevention and treatment of acute radiation esophagitis during the radiotherapy for esophageal carcinoma.Methods72 cases of esophageal carcinoma patientswith thoracic radiotherapy in the First Affiliated Hospital of Henan University of Science and Technology from May 2014 to November 2015 were randomly divided into experimental group and control group.Patients in the experimental group group received reduced glutathione combined with anti-inflammatory analgesic mixture during radiotherapy,while patients in the control group received anti-inflammatory alone.The incidence of actue radiation esophagitis,tolerance dose of esophagealmucosal and the proportion of patients for whom antibiotics were used in two groups were experimentald and evaluated.Results72 patients all completed the treatment course.The incidence of gradeⅡor above actue radiation esophagitiswas 100.0%in two groups,The incidence of grade Ⅱor above actue radiation esophagitis in the experimental group and the control group was 33.3%and 63.9%respectively,and the difference was statistically significant(χ2=6.727,P<0.01),there were no gradeⅣacute esophagealmucosal injury in the two group.The tolerance dose of esophagealmucosa in the experimental group was higher than that in the control group (P<0.01).Use proportionof antibiotics in the treatment of radiation esophagitis in the experimental group was 13.9%,with 44.4%in the control group,and the difference was statistically significant(χ2=8.314,P=0.004).ConclusionReduced glutathione has a good effect on the prevention and treatment of acute esophagealmucosal injury in patientswith esophageal carcinoma.It can reduce the incidence and severity of acute radiation esophagitis. 2016 Vol. 23 (33): 31-33 [Abstract] ( 151 ) HTML (37 KB)  PDF  (0 KB)  ( 34 ) 34 Research of the clinical value of AIMS65 scoring system in the evaluation of upper gastrointestinal hemorrhage WANG Fei;ZHANG Dan;WANG Yun-ye ObjectiveTo explore the clinical predictive value of AIMS65 scoring system in upper gastrointestinal hemorrhage through retrospective analysis its mortality,rate of blood transfusion,rebleeding rate.MethodsClinical data of 567 cases of upper gastrointestinal hemorrhage admitted into our hospital from January 2011 to December 2015 were retrospectively analyzed.According to the score (0 to 5 points),which were divided into 6 groups,mortality,rate of blood transfusion,rebleeding rate among groupswere compared.The ROC curve was used to calculate the area under the curve (AUC)to evaluate the value of the scoring system in predicting the death,blood transfusion and rebleeding of upper gastrointestinal hemorrhage.ResultsThe mortality of 1-6 groups was 0.0%,2.9%,12.7%,29.2%,42.9%and 94.4%respectively;rate of blood transfusion rate was 9.3%,17.1%,27.1%,44.1%,50.0%,72.2%respectively;rebleeding rate was 3.3%,6.4%,5.4%,11.8%,13.3%,22.2%respectively.The AUC ofmortality,rate of blood transfusion,rebleeding rate was 0.888,0.723 and 0.649 respectively.When AUC≥0.7,scoring system had good diagnostic value.ConclusionAIMS65 scoring system for upper gastrointestinal bleeding mortality,blood transfusion rate has a good diagnostic value,the rebleeding rate of diagnosis is low,the score is simple,easy to clinical collection,has a good clinical value. 2016 Vol. 23 (33): 34-36转49 [Abstract] ( 153 ) HTML (37 KB)  PDF  (0 KB)  ( 39 ) 37 Effect observation of thrombus aspiration combined with Tirofiban Hydrochloride for coronary injection in emergency intervention for acute m yocardial infarction LIUMu-sheng ObjectiveTo explore the application effect of thrombus aspiration combined with Tirofiban Hydrochloride for coronary injection in emergency intervention for acute myocardial infarction.Methods48 patients with acute ST segment elevation and given emergency percutaneous coronary intervention(PCI)from January 2013 to December 2015 were selected.Coronary angiography showed significant thrombus burden,and patients were divided into two groups according to treatmentmethod.Observation group (n=20)was given thrombus aspiration combined with Tirofiban Hydrochloride for coronary injection while control group (28 cases)was given only PCI.Clinical efficacy and safety was observed.ResultsIn observation group,TIMI3 level of blood flow,the percentage of ST segment fell after 2 h operation and enzyme peak time were better than those of control group (P<0.05).The incidence rate of no reflow or slow flow of IRA was lower than that of control group(P<0.05).At 3months,LVEF and LVEDd in observation group were better than those of control group (P<0.01),and during hospitalization,the incidence rate of MACE in observation group was lower than that of control group(P<0.05).The incidences of bleeding of the two groups was not statistically significant(P> 0.05).ConclusionThrombus aspiration combined with Tirofiban Hydrochloride treating acutemyocardial infarction with ST segment elevation can reduce no-reflow or slow flow,improvemyocardial perfusion and improve the prognosis. 2016 Vol. 23 (33): 37-39 [Abstract] ( 138 ) HTML (38 KB)  PDF  (0 KB)  ( 34 ) 40 Relationship between acute left heart failure,m itral stenosis com p licated with acute pulmonary edema and circulation N-term inal pro-brain natriuretic peptide WEN Liang-fa;FU Xiang;XIEQun-xing;FU Xiao-ding ObjectiveTo explore the relationship between acute left heart failure,mitral stenosis complicated with acute pulmonary edema and circulation N-terminal pro-brain natriuretic peptide(NT-proBNP).MethodsFrom January 2013 to January 2016,patientswith acute left heart failure(the study group,n=72)ormitral stenosis complicated with acute pulmonary edema (the control group,n=27)in our hospital were selected.The cardiac function and plasma NT-proBNP concentration were analyzed,and the relationship between different cardiac functional grading and plasma NT-proBNP concentration in the study group was analyzed.ResultsThere was no significant difference for percentage of patients with different cardiac functional grading between two groups (χ2=29.9332,P<0.01).There was no significant difference for percentage of patients with NYHA gradeⅢ (χ2=2.905,P=0.088).Percentage of patients with NYHA gradeⅡand Ⅳin two groups had a statistical difference(χ2=29.236,14.243,P<0.01),and variance analysis showed that there was a significant difference of plasma NT-proBNP concentration in patients with different cardiac functional grading (P< 0.01).ConclusionExamination of plasma NT-proBNP concentration is easy and simple with good accuracy,which can be considered as one of reliable indexes to quickly distinguish acute left ventricular failure and mitral edema associated complicated with pulmonary edema and it has a better practicability to reflect and evaluate cardiac function of patients. 2016 Vol. 23 (33): 40-43 [Abstract] ( 138 ) HTML (42 KB)  PDF  (0 KB)  ( 37 ) 44 Application of Furosem ide combined with Enalapril in treating heart failure due to chronic pulmonary heart disease ZOU Bin;ZOU Rong ObjectiveTo study the clinical effect of Furosemide combined with Enalapril treating heart failure due to chronic pulmonary heart disease.Methods92 patientswith heart failure due to chronic pulmonary heart disease treated by our hospital from May 2014 to May 2016 were selected and they were randomly divided into control group and treatment group,and each group had 46 cases.Control group was treated by Enalapril,while treatment group was treated by Furosemide combined with Enalapril.The improvement degree of related biochemical index level before and after treatment,drug treatment effect,disappear time of heart failure symptom,total time of drug treatment for heart disease and related adverse reaction during treatment between two groupswas compared respectively.ResultsThe improvement degree of related biochemical index level before and after treatment in treatment group were obvious larger than those in control group and disappear time of heart failure symptom and total time of drug treatment for heart disease in treatment group were obviously shorter than those in control group,and drug treatment effect in treatment group was obviously better than that of control group (P<0.05).There was no statistical difference of incidence of adverse reaction between two groups(P＞0.05).ConclusionFurosemide combined with Enalapril treating heart failure due to chronic pulmonary heart disease has a very obvious clinical effect. 2016 Vol. 23 (33): 44-46 [Abstract] ( 157 ) HTML (37 KB)  PDF  (0 KB)  ( 38 ) 47 Effect observation of Am lodipine besylate in the treatment of m ild to moderate hypertension in community LIYan-qin ObjectiveTo evaluate the clinical efficacy of Amlodipine besylate in the treatment ofmild tomoderate hypertension in community,and to provide reliable data for clinical treatment.MethodsA total of 110 patientswithmild to moderate hypertension treated by Community Health Centre of Liangxiang Region from May 2014 to May 2016 were selected as object.They were simply and randomly divided into the control group(n=55)and the observation group(n= 55).After patients were given healthy life guidance,control group was given treatment plan of oral Nifedipine,while observation group was treatment plan of oral Amlodipine besylate.After treatment,the blood pressure control level,total effective rate and incidence of adverse reaction in two groupswere observed.ResultsAfter 8 weeks treatment,the diastolic blood pressure of the patients in observation group was(86.25±4.15)mmHg,the systolic blood pressure was (118.20± 2.13)mmHg,the total effective ratewas 94.55%,and the incidence of adverse reaction was 3.64%.The above-mentioned 4 sets of data in observation group were better than those of control group[(95.23±5.30)mmHg,(143.35±5.92)mmHg, 80.00%,20.00%](P<0.05).ConclusionAmlodipine besylate is effective in the treatment ofmild tomoderate hypertension in community.It has fewer adverse reaction and convenient administration.It isworth to be promoted and applied in community. 2016 Vol. 23 (33): 47-49 [Abstract] ( 145 ) HTML (40 KB)  PDF  (0 KB)  ( 26 ) 50 Effect of behavior modification training on reducing the bad behavior of patientswith chronic schizophrenia LIANGMei-juan;WANG Hai-xia ObjectiveTo study the effects of behavior modification training on life quality of chronic schizophrenia.MethodsSixty patients with chronic schizophrenia from January to December in 2015 in our hospital were randomly divided into observation group and control group,30 patients in each group.Control group was given the normal treatment and nursing,and the observation group was given the behavior modification training in addition,the two groups were observed for 6 months,the results were evaluated by IPROS and NOSIE-30.ResultsThe scores of IPROS in the observation group were significantly lower than those of the control group,the differences were statistically significant (P<0.01).In NOSIE-30 score,the scores of total positive factors in the observation group was higher than those of the control group and the scores of total negative factorswas lower than those of the control group,the differenceswere statistically significant(P＜0.01).ConclusionThe behaviormodification training can effectively improve the social function of patientswith chronic schizophrenia. 2016 Vol. 23 (33): 50-52 [Abstract] ( 148 ) HTML (38 KB)  PDF  (0 KB)  ( 35 ) 53 Effect of early high strength functional exercise on postoperative rehabilitation of patientswith cerebral hemorrhage LU Xi-zhang ObjectiveTo explore the curative effect of early high strength functional exercise on the rehabilitation of patients with cerebral hemorrhage after operation.MethodsClinical data of 68 patients with cerebral hemorrhage from July 2014 to July 2016 in our hospitalwere retrospectively analyzed,patients of the two groupswere given postoperative limb function training,34 cases of the passive exercise were selected as control group,and 34 patients of the active exercise were selected as the observation group,mainly for the early strength of physical function training,and the relevant indexes and effect of patients in the two groups before and after exercise were compared.ResultsThere was no significant difference between the two groups in human albumin and CD4/CD8 before exercise (P>0.05),with functional exercise,each index of two groupswere significantly increased after 14 d of exercise,the level of human albumin in the observation group and control group was(40.18±3.30),(36.16±6.77)g/L respectively,and the CD4/CD8 was(2.22±0.51)and (1.32±0.71)respectively,the difference was statistically significant(P<0.05);the incidence of complications in the observation group was significantly lower than that of the control group(P<0.05).ConclusionThe early strength of limb function exercise can reduce the complications of patientswith cerebral hemorrhage,promote the recover of patients,and enhance the immunity. 2016 Vol. 23 (33): 53-55 [Abstract] ( 151 ) HTML (35 KB)  PDF  (0 KB)  ( 15 ) 56 Change study of blood procalcitonin,interleukin-6,endotoxin Limulus after m ini-percutaneous nephrolithotom y DU Chuan-ce;WU Xiao-yuan;SONG Le-ming;LIQi-shan ObjectiveTo explore the changes of procalcitonin(PCT),interleukin-6 (IL-6)and endotoxin limulus after suctioningmini-percutaneous nephrolithotomy(SMPCNL).Methods122 patients with percutaneous nephrolithotomy indications in our hospital from July 2014 to July 2015 were selected as study object,no surgical contraindications. According to odd and even numbers of admission time,patients were divided into two group,patients in SMPCNL group was given SMPCNL,with a total of 62 cases;patients in traditionalmini-percutaneous nephrolithotomy (MPCNL)group were given MPCNL,with no negative pressure suction,a total of 60 cases.The levels of PCT,IL and endotoxin limulus weremeasured and compared before and after operation for 1 day.ResultsThe level of PCT,IL-6 and endotoxin limulus was(0.056±0.011)ng/ml,(5.4±3.9)pg/ml and (0.56±0.34)EU/ml respectively in SMPCNL group before operation,with (0.336±0.230)ng/ml,(6.9±4.5)pg/ml,(1.68±0.57)EU/ml respectively after operation for 1 day;and the levels of PCT,IL-6 and endotoxin limuluswas(0.050±0.021)ng/ml,(5.2±4.1)pg/ml,(0.55±0.27)EU/ml respectively in MPCNL group before operation,with (3.652±1.680)ng/ml,(8.9±5.6)pg/ml,(3.27±2.12)EU/ml respectively after operation for 1 day,there was no significant difference in PCT,IL-6 and endotoxin limulus value between two groups before operation(P>0.05); serum PCT,IL-6,endotoxin limulus values in two groups after operation for 1 day was higher than that before operation (P<0.05);serum PCT,IL-6 and endotoxin Limulus value in the SMPCNL group after operation for 1 day was lower than that in the MPCNL group after operation for 1 day,and the difference was statistically significant(P<0.05).ConclusionSerum PCT,IL-6 and endotoxin limulus concentration are good indicators formonitoring percutaneous nephrolithotomy as an indicator of inflammatory reaction.Inflammatory response after SMPCNL is lower than that of MPCNL. 2016 Vol. 23 (33): 56-58 [Abstract] ( 169 ) HTML (38 KB)  PDF  (0 KB)  ( 36 ) 59 Analysis of the effect and safety of Tam sulosin in the treatment of patientswith benign prostatic hyperp lasia LUO Ling-jian;CHENWei;FU En-jun ObjectiveTo explore the effect and safety of Tamsulosin in the treatment of patients with benign prostatic hyperplasia.Methods60 cases of benign prostatic hyperplasia in our hospital from May 2013 to May 2016 were selected as study objectand randomly divided into two groups,30 cases in each group.Patients in the control group was treated with Terazosin hydrochloride,while patients in the experimental group received Tamsulosin treatment,quality of life score(QOL),international prostate symptom score(IPSS),maximum urinary flow rate(MFR)before and after treatment in two groups and adverse reaction incidence rate were compared.ResultsAfter treatment,QOL,IPSS and MFR in two groupswas significantly improved (P<0.05),but QOL and IPSS in the experimental group was significantly better than that in the control group(P<0.05),and MFR between two groups had no significant difference(P>0.05).Adverse reaction rate in the control group was 30.00%,significantly higher than 6.67%in the experimental group,and the difference was statistically significant(P<0.05).ConclusionTamsulosin in the treatment of benign prostatic hyperplasia has significant clinical effect and higher safety. 2016 Vol. 23 (33): 59-61 [Abstract] ( 158 ) HTML (38 KB)  PDF  (0 KB)  ( 21 ) 62 Clinical study on acupoint plant line in the treatment of knee osteoarthritis ZHAO Chang-wei;ZHAOWen-hai;WEN Hui;HUANG Dan-qi ObjectiveTo observe the clinical efficacy of acupoint plant line in the treatment of knee osteoarthritis (KOA).Methods60 patients diagnosed with KOA in our hospital from May 2014 to June 2015 were selected and treated by acupoint plant line,after treatment for 15 days,according to special checking of pain,activity and pain,functional activity,patientswere scored,all indexes before and after treatmentwere compared.ResultsAfter treatment,the total efficiency was 93.33%;after treatment,the clinical observation index score was lower than that before treatment,and the difference was statistically significant(P<0.05).ConclusionAcupoint plant line in the treatment of KOA can obviously improve the symptoms and signs,the operation is simple and easy to popularize. 2016 Vol. 23 (33): 62-64 [Abstract] ( 134 ) HTML (37 KB)  PDF  (0 KB)  ( 33 ) 65 Effect observation of open tibial fractures of Gustifo grade-ⅢA treated by internal fixation inⅠstage HUANG Ji-jia;CHEN Ge-hai;HUANGWei-zhen;JIANGQin-wen;LAIPei-qun ObjectiveTo explore the effect difference of open tibial fractures of Gustifo grade-ⅢA patients treated by internal fixation inⅠstage and external fixation.Methods82 patients with open tibial fractures of Gustifo grade-ⅢA in Departmentof Orthopedics of Our Hospital from January 2014 to March 2016 were seleted and divided into observation group(41 cases)and control group(41 cases),Patients in the observation group were givenⅠstage internal fixation,while patients in the control group received external fixation treatment,healing effects in two groupswere compared.ResultsThe recovery of affected limb function in the observation group was better than that in the control group,and the differencewas statistically significant(P<0.05);the fracture healing rate was 97.56%in the observation group,significantly higher than 73.17%in the control group,and the difference was statistically significant(P<0.01);the infection rate of wound and external fixator in the observation group was 4.88%,significantly lower than 24.39%in the control group,and the difference was statistically significant(P<0.01).ConclusionPatientswith open tibial fractures of Gustifo grade-ⅢA treated withⅠstage fixation can significantly improve the functional recovery of affected limb and fracture healing rate,which is beneficial to the recovery of the fracture after treatment. 2016 Vol. 23 (33): 65-67 [Abstract] ( 149 ) HTML (36 KB)  PDF  (0 KB)  ( 30 ) 68 Clinical effect analysis of m inimally invasive DHS in the treatment of femoral intertrochanteric fracture LI Yong ObjectiveTo explore the clinical efficacy ofminimally invasive dynamic hip screw (DHS)in the treatment of femoral intertrochanteric fractures.Methods64 cases of elderly patientswith femoral intertrochanteric fracture treated in our hospital clinic from January to June 2016 were selected as research targets.Patientswere divided into observation group(32 cases)and control group(32 cases)by random number table.The observation group was givenminimally invasive DHS surgery treatment and the control group was given traditional DHS surgery treatment.Clinical data of operation condition,postoperative complication and Harris hip scores between two groups were compared after postoperative followed up for 1 month.ResultsThe operation time,intraoperative blood loss and the length of incision in the observation group was superior to that in the control group,and the difference was statistically significant(P＜0.01).The postoperative nonunion and avascular necrosis of femoral head in the observation group was respectively 0 cases,2 cases of postoperative wound infection;2 cases of nonunion,1 cases of avascular necrosis of femoral head,3 cases of incision infection after operation was in the control group.The postoperative complication rate in the observation group was 6.25%,lower than 18.75%in the control group,and the differencewas statistically significant(P＜0.05).In Harris hip scores,the excellent rate of the observation group(96.88%)was higher than that of the control group(75.00%),and the difference was statistically significant(P＜0.05).ConculsionAs for femoral intertrochanteric fracture,minimally invasive DHShas the advantage ofminimal trauma and a low occurrence of complication,and it isworthy of clinical promotion. 2016 Vol. 23 (33): 68-70 [Abstract] ( 167 ) HTML (37 KB)  PDF  (0 KB)  ( 7 ) 71 Effect observation of hip arthrop lasty in the treatment of femur intertrochanteric fracture with severe comm inuted dislocation HUA Han ObjectiveTo analyze the effect of hip arthroplasty in the treatment of femur intertrochanteric fracture with severe comminuted dislocation.Methods82 patientswith femur intertrochanteric fracture with severe comminuted dislocation were in our hospital from May 2014 to June 2016 divided into treatment group and reference group according to the parallel controlmethod,41 cases in each group.Patients in the reference group were treated with internal fixation, and patients in the treatment group were treated with hip arthroplasty.The clinical therapeutic effects of two groups were compared.ResultsTime of postoperative joint activity returning to normal,fracture healing time and Harris score in the treatment group was significantly better than that in the reference group,therewas significant difference[(7.23±1.74) d vs(13.82±2.39)d,(92.56±9.35)d vs(103.78±10.56)d,(95.45±7.23)scores vs(81.56±14.75)scores,P<0.01].ConclusionThe clinical effect of hip arthroplasty in patientswith femur intertrochanteric fracture with severe comminuted dislocation ismore significant than that of internal fixation,which can effectively improve the healing effect of fracture and accelerate the rehabilitation of patients.It isworthy to bewidely used in clinic. 2016 Vol. 23 (33): 71-73 [Abstract] ( 175 ) HTML (35 KB)  PDF  (0 KB)  ( 16 ) 74 Application effect of AO special plate in the treatment of proximal joint fractures WANG Shui-bin;WANG Guo-liang;HAO Qun-yu ObjectiveTo explore the treatment effect of AO special plate in the treatment of proximal joint fracture.Methods67 cases of proximal joint fractures treated in our hospital from July 2014 to July 2015 were selected and the clinical data were retrospectively analyzed.The patients were divided into two groups according to the different treatmentmethods,33 patients treated with traditional steel plate were as traditional group,34 patients treated with AO special plate were as study group.All patientswere followed up for 12 months,operation-related indexes,joint function and postoperative complications were observed.ResultsOperation time,hospitalization time and fracture healing time in the study group was significantly shorter than that in the traditional group (P<0.05);the excellent and good rate of joint function in the study group was 94.12%,which was significantly higher than 75.75%in the traditional group (P<0.05); the incidence of postoperative complications in the study group was 8.82%,which was significantly lower than 30.30% in the traditional group (P<0.05).ConclusionAO special steel plate in the treatment of proximal joint fracture can shorten surgery time and hospitalization time,which is conducive to fracture healing,joint function recovery,less complications,and is a safe and effective treatmentmeasures. 2016 Vol. 23 (33): 74-76 [Abstract] ( 156 ) HTML (39 KB)  PDF  (0 KB)  ( 30 ) 77 Clinical effect of DHS spiral blade in the treatment of Evans-Jensen type Ⅰ,Ⅱintertrochanteric fractures LIU Li-jin;TANGWu-bin ObjectiveTo study the clinical significance of dynamic hip screw(DHS)spiral blade in the treatment of sta ble femoral intertrochanteric fracture.Methods48 elderly patients with Evans-JensenⅠ,Ⅱfemoral intertrochanteric fracture in our hospital from January 2011 to September 2015 were selected as study object and divided into DHS spiral blade group (n=28）and proximal femoral nail antirotation (PFNA)group (n=20)according to different treatment methods,DHS spiral blade group were treated by DHS spiral blade,while PFNA group was treated by PFNA.Treatment effects between two groups were compared.ResultsAfter 12 months followed-up,there was no statistical difference in operation time,length of hospital stay,healing time of fracture,blood loss volume during operation between two groups (P＞0.05);perioperative total blood loss,intraoperative fluoroscopy time in the DHS spiral blade group was obviously less than that in the PFNA group,and the difference was statistically significant(P<0.05).There was no statistical difference in excellent and good rate of hip joint function after operation between two groups(P＞0.05).ConclusionThe therapeutic effect of PFNA and DHS spiral blade are good in the treatment of stable femoral intertrochanteric fracture.DHS spiral blade has advantages to reduce perioperative total blood loss and intraoperative fluoroscopy time. 2016 Vol. 23 (33): 77-79 [Abstract] ( 120 ) HTML (41 KB)  PDF  (0 KB)  ( 30 ) 80 The app lication of"three-dimensional orthopedic idea"in the treatment of double forearm fracture WANG Guang-wei;HUO Li-wei;YUWei-zhong;YE Yong-liang;HUANG Chong-bo ObjectiveTo observe the effect"three-dimensional orthopedic idea"and suegery in the treatment of double forearm fractures,reveal"three-dimensional orthopedic idea"treatmentmechanism and promote the clinical application of"three-dimensional orthopedic idea".MethodsIn accordance with the principle of randomization,86 patients with double forearm fracture from July 2010 to July 2015 were included in this study and randomly divided into two groups. 43 cases of experimental group were treated with"three-dimensional orthopedic idea",43 cases of control group were treated with internal fixation.After treatment for 3 months and 6 months respectively,fracture reduction,healing,forearm function recovery and curative effectwere compared.ResultsAfter treatment for 3months,fracture healing,functional recovery and overall efficacy in the experimental group was better than that in the control group,and the difference was statistically significant(P<0.01).After treatment for 6months,functional recovery and overall efficacy in the experimental group was better that in the control group,and the difference was statistically significant(P<0.01);after treatment for 6 months,there was no significant difference in fracture healing between the experimental group and the control group (P=0.080).Fracture alignment in the control group was better than that in the experimental group,and the difference was statistically significant(P=0.000).ConclusionThe use of"three-dimensional orthopedic idea"treating double forearm fractures has the advantages of shorter fracture healing time and good functional recovery etc.,which isworthy of clinical popularization and application. 2016 Vol. 23 (33): 80-84 [Abstract] ( 155 ) HTML (64 KB)  PDF  (0 KB)  ( 38 ) 85 Effect observation of Shenyi Capsules in the maintenance treatment of advanced non-small cell lung cancer LIU Zun-tao;LIHong-yan ObjectiveTo invesigate the effect of Shenyi Capsules for advanced non-small cell lung cancer(NSCLC) maintenance treatment.MethodsFrom July 2013 to October 2015,90 cases of advanced NSCLC patients with stage Ⅲb~Ⅳ were divided into control group and study group according to the random number table method,45 cases in each group.Control group was treated with pemetrexed,study group was treated with Shenyi Capsules.Patients of the two groups were treated for four cycles.The rate of total effective,rate of treatment benefit,KPS score,and immune function indexes such as CD3+,CD4+,CD8+,CD4+/CD8+of the two groups before and after treatmentwere compared;the adverse reactions of the two groupswere compared.ResultsThe total effective rate of the study group was 53.33%,and the rate of therapeutic benefitwas 84.44%,which were significantly higher than those of the control group (31.11%,66.67%),the differenceswere statistically significant(P<0.05).After treatment,the total increase rate of KPS score in the study group was significantly higher than that of the control group,and the immune function indexes of the two groups were significantly lower than those before treatment,and study group was higher than those of the control group,the differenceswere statistically significant(P<0.05);there was no serious adverse reactions in two groups.ConclusionShenyi Capsules maintenance treatment can significantly improve the efficiency,the quality of life and immune function of patients with advanced NSCLC,so it isworthy of clinical application. 2016 Vol. 23 (33): 85-87转97 [Abstract] ( 141 ) HTML (41 KB)  PDF  (0 KB)  ( 35 ) 88 Clinical study of the application of vertebroplasty in neuro spinal tumor surgery FENG Kai-ming;ZHU Fu-bin ObjectiveTo explore the clinical effect of vertebroplasty in neuro spinal tumor surgery.MethodsClinical data of 40 patientswith spinal tumor treated in the People′s Hospital of Ganzhou City from February 2014 to May 2016 were retrospectively analyzed,according to the surgicalmethods they were divided into two groups:experimental group (half laminectomy and anatomic reduction)and control group(half laminectomy butwithout anatomic reduction),20 cases in each group.The incidence of spine deformation and iatrogenic spinal stenosis,and quality of life in two groups were compared.ResultsThe bone fusion time,VAS score and Cobb angle in the experimental group were all lower than the control group (P<0.05).The incidence of spine deformation in the experimental group and control group was 10% and 20%respectively,while the incidence of iatrogenic spinal stenosis was 5%and 15%respectively.The incidence of spine deformation and iatrogenic spinal stenosis between two groups had no statistical difference (P>0.05).ConclusionCompared with the half laminectomy,half laminectomy and anatomic reduction show a significant effect in neuro spinal tumor surgery,which can effectively preserve spinal instability,reduce the incidence of postoperative spine deformation and iatrogenic spinal stenosis and improve the quality of life of patients. 2016 Vol. 23 (33): 88-90 [Abstract] ( 144 ) HTML (38 KB)  PDF  (0 KB)  ( 37 ) 91 Expression and clinical significance of serum free am ino acids and pulmonary surfactant proteins of patientswith pulmonary cancer CHENG Ting ObjectiveTo study and analyze the expression and clinical significance of serum free amino acids and pulmonary surfactant proteins of patients with pulmonary cancer.MethodsSeventy patients with pulmonary cancer from July 2015 to May 2016 in the Second People′s Hospital of Wuxi City were selected as the observation group,and 70 healthy personswere selected as the control group,then the serum free amino acids and pulmonary surfactant proteins of two groupswere detected and compared,then the serum free amino acids and pulmonary surfactant proteins of observation group with different types and stages of pulmonary cancer were compared too,and the relationship between the serum free amino acids,pulmonary surfactant proteins and pulmonary cancer were analyzed by the Logistic analysis.ResultsThe serum free amino acids of observation group were all worse than those of control group,serum pulmonary surfactant proteins A,B,C were all higher than those of control group(P<0.05),and the detection results of serum free amino acid and pulmonary surfactant proteins of patientswith different clinical stages of pulmonary cancer had statistically significant differences (P＜0.05),while the detection results of serum free amino acid and pulmonary surfactant proteins of patients with different types had no statistically significant differences (P＞0.05);Logistic analysis showed that,the serum free amino acids and pulmonary surfactant proteins all had close relationship with the pulmonary cancer(P＜0.05).ConclusionThe detection value of serum free amino acids and pulmonary surfactant proteins of patients with pulmonary cancer are higher,and its clinical significance for the stages of pulmonary cancer is higher too. 2016 Vol. 23 (33): 91-93 [Abstract] ( 134 ) HTML (38 KB)  PDF  (0 KB)  ( 41 ) 94 Analysis of the clinical efficacy and safety of Gem citabine combined with Capecitabine in the treatment of advanced breast cancer with Anthracycline resistance GUOQing-sen ObjectiveTo explore the clinical efficacy and safety of Gemcitabine combining with Capecitabine in the treatment of advanced breast cancer with Anthracycline resistance.MethodsFrom June 2013 to November 2015,79 patients definitely diagnosed as advanced breast cancer with Anthracycline-resistant in our hospital were enrolled in the study and randomly assigned to control group (n=39)and observation group (n=40).In the control group,patientswere treated with Docetaxel and Capecitabine,while in the observation group,Gemcitabine combined with Capecitabine was used.After 2 cycles of treatment,the difference of clinical curative effect,the digestive tract discomfort inⅢandⅣdegrees and the occurrence of side effects such as bonemarrow suppression were compared between the two groups.ResultsThe total remission rate in the observation group was 47.50%,was higher than that in the control group (25.64%), the difference was statistically significant(P<0.05);the clinical total benefit rate in the control group was 76.92%,while the observation group was 80.00%,had no statistically significant difference between two groups(P>0.05);the incidence of digestive tract discomfort in degreeⅢ andⅣ and myelosuppression in the observation group was 17.50%and 22.50%,was lower than those of the control group (38.46%,43.59%),and the overall incidence of the digestive tract discomfort in degreeⅢandⅣand myelosuppression between the two groups had statistically significant difference (P< 0.05).ConclusionCombination of Gemcitabine and Capecitabine in the treatment of advanced breast cancer with Anthracycline-resistanthas a great effect,with few adverse reactions,it isworthy of promotion. 2016 Vol. 23 (33): 94-97 [Abstract] ( 148 ) HTML (40 KB)  PDF  (0 KB)  ( 30 ) 98 Clinical analysis of Docetaxel combined with Nedaplatin in the treatment of advanced esophageal cancer WANG Lei ObjectiveTo observe the curative effect and adverse reaction of Docetaxel combined with Nedaplatin in treatment of advanced esophageal cancer.MethodsFifty-four patients with advanced esophageal from March 2013 to November 2015 were randomly divided into two groups.The patients in treatment group were given Docetaxel combined with Nedaplatin，and the patients in control group were given Docetaxelwith Cisplatin.The curative effectwas evaluated after the end of two cycles of treatment and the adverse reaction was observed.ResultsThe effective rate in the treatment group was 55.56%，and the control group was 48.15%.The disease control rate in the treatment group was 85.19%，and the control group was 81.48%，there was no statistically significant differences in effective rate and disease control rate between two groups （P>0.05）.The adverse reactions were maily vomiting，leucopenia，thrombocytopenia，kidney dysfunction，and the degree of adverse reactions of them in the treatment group was lower than that of the control group（P<0.05）.ConclusionCompared with the Docetaxel and Cisplatin，the treatment of advanced esophageal cancerwith Docetaxel and Nedaplatin has a similar curative effect，few adverse reactions and good tolerance of patients. 2016 Vol. 23 (33): 98-100 [Abstract] ( 123 ) HTML (36 KB)  PDF  (0 KB)  ( 36 ) 101 Effect of mobile message service on im proving of the treatment effect of community children with im paired glucose tolerance MAO Hua CAO Xue-mei ObjectiveTo explore the effectofmobilemessage service(MMS)on improving of the treatmenteffectof community children with impaired glucose tolerance.MethodsFrom January 2013 to December 2015,120 children with impaired glucose tolerance from our hospital under the jurisdiction of seven community centers(total population 160,000) were selected.They were numbered according to the order of treatment and allocated by SPSS software in random.Children were divided into control group and observation group averagely by single-blind method,and he age,gender,and course of disease in each group or between groups had no great difference.In the control group,traditional teaching method was used to normalize the diet and the exercise as a cooperation,while in the observation group,on the basis of the control group,MMSwas added.The total effective rate of intervention and score of satisfaction on nursing service by children′s parents in the two groups were compared.ResultsThe total effective rate of intervention in the observation group was remarkably higher than that in the control group (P<0.01).The score of satisfaction on nursing service by children′s parents in the observation group was alsomuch higher than that in the control group (P<0.05).ConclusionOn the basis of normalizing diet and exercise as a cooperation,application of MMS can improve the treatment effect of children with impaired glucose tolerance in community,and get a higher satisfaction from children′s parents,it isworthy of promoting. 2016 Vol. 23 (33): 101-103 [Abstract] ( 106 ) HTML (36 KB)  PDF  (0 KB)  ( 41 ) 104 Clinical study of gestational hypertension retinopathy and prognosis of perinatal infants WANG Ying;CAIXin;YAO Xiao-li;AIGuo-hua;RU Hai-yan;QUMei-yu;QIU Xiao-mei ObjectiveTo provide an effective examination and treatmentways for gestational hypertension in clinical by analyze the relationship between retinopathy and its classification of the gestational hypertension with prognosis of perinatal infants.Methods2388 pregnant women in our hospital from June 2013 to June 2015 were selected,with which 150 cases got gestational hypertension and 6 caseswere lost.150 patientswith gestational hypertension were divided into the following four groups:gestational hypertension group,mild preeclampsia group,severe preeclampsia group and eclampsia group.The incidence and stage of retinopathy in the four groupswere analyzed.The prognosis of perinatal infantswere evaluated with the Apgar score.The relationship between the retinopathy stage and the development of high blood pressure in pregnancy,the prognosis of perinatal infantswere analyzed.ResultsOf the 150 patientswith gestational hypertension,there were 60 cases in the gestational hypertension group,38 cases in the mild preeclampsia group, 29 cases in the severe preeclampsia group and 23 cases in the eclampsia group,and the number of patientswith retinopathy was 46(76.7%),33(86.8%),28(96.5%)and 23(100.0%),respectively,the incidence of retinopathy with different stage: stageⅠ was 63.3%,34.2%,10.3%,respectively,0;stageⅡ was 26.7%,55.3%,27.6%,14.8%,respectively;stageⅢ was 10.0%,10.5%,62.1%,82.6%,respectively.The incidence of fetal with poor prognosis of patients with different stage of retinopathy was 7.4%(stageⅠ),12.1%(stageⅡ),26.8%(stageⅢ),respectively,the difference was statistically significant(P<0.05).ConclusionThe development of retinopathy of patients with gestational hypertension is close related with the prognosis of fetus,thus the evaluation of illness condition timely and take correspondingmeasures can reduce the incidence of retinopathy and severity. 2016 Vol. 23 (33): 104-106转110 [Abstract] ( 108 ) HTML (43 KB)  PDF  (0 KB)  ( 30 ) 107 Clinical analysis of IVF-ET in infertility patients after cervical conization WANGMei-xian;WANG Lei;TAN Hai-ying;SHAO Xiao-guang ObjectiveTo examine the effect of cervical conization on in vitro fertilization-embryo transfer(IVF-ET)and pregnancy.MethodsThe IVF-ET scheme,laboratory index,and pregnancy outcome of 36 patients with cervical conization (study group)from January 2012 to December 2014 in our center were analyzed,and were compared with 350 patientswithout cervical conization (control group)at the same period.ResultsThere were no statistically significant differences in IVF-ET scheme,the number of retrieved oocytes,and the rate of oocyte-obtained,fertilization,good quality embryo,pregnancy,early abortion,ectopic pregnancy of fresh cycle transplantation between two groups(P>0.05).The number of transferred embryos in the study group was significantly less than that of the control group (P<0.01),however,the rate of embryo reduction was higher(P<0.01).The rate of cesarean section had no statistically significant difference between the two groups(P>0.05),the rate of premature rupture ofmembrane,preterm birth,low birth weight children rate in study group was a little higher than that of the control group,but had no statistically significant difference (P>0.05).ConclusionThere is no significant difference in IVF-ET protocol between patients with cervical conization and other patients,itwould not affect the pregnancy rate usingmore less of embryos in order to reducemultiple pregnancy. 2016 Vol. 23 (33): 107-110 [Abstract] ( 139 ) HTML (42 KB)  PDF  (0 KB)  ( 37 ) 111 Clinical study of Ganciclovir combined Naloxone in the treatment of 60 children with viral encephalitis LONG Chun-gen ObjectiveTo investigate the clinical effect of the treatment with Ganciclovir combined Naloxone on pediatrics of viral encephalitis.MethodsAccording to the draw method 60 children with viral encephalitis admitted in our hospital from March 2012 to August 2015 were randomly divided into experimental and control group,30 cases in each group.Statistical analysiswas used to analyze the disappearance time of the related clinical symptoms,clinical effects, relevant laboratory results of patients after the treatment in the two groups.ResultsThe time of the experimental group which was related to clinicalmanifestations disappeared or reduced was significantly shorter than the control group(P< 0.05);the clinical efficacy of the experimental group was superior than the control group (P<0.05);the condition of liver function and renal damage of patients in the experimental group was obviously better than that of the control group(P< 0.05).ConclusionGanciclovir combined with Naloxone can significantly improve the clinical efficacy of children with viral encephalitis,and improve the prognosis and reduce the complications. 2016 Vol. 23 (33): 111-113 [Abstract] ( 111 ) HTML (39 KB)  PDF  (0 KB)  ( 39 ) 114 Com parative study of M agnetostrictive comprehensive and traditional basic treatment of periodontal in the treatment of chronic periodontitis LIYan;LIHui-shan;WANG Ruo-li;LIXiao-ming ObjectiveTo explore the comparative subjective evaluation and the efficacy of Magnetostrictive comprehensive treatment in periodontal therapy for the treatment of chronic periodontitis between Bangwo ultrasonic subgingival scaler and conventional periodental ultrasonic subgingival scaler.MethodsFifty-six patients with periodontitis from November 2014 to May 2016 in our hospital were chosen and divided into two groups according to their registered numbers,with 28 cases in each group.Bangwo ultrasonic subgingival scaler ofmagnetostrictive comprehensive therapeutic instrument was used in the observation group,while the conventional multifunction dentistry treatment instrument (Suprasson P5 newtron)was used in the control group.Gingival index (GI),periodontal depth (PD),bleeding on probing (BOP)and dental fear survey (DFS)score before the operation and 3months after the operation of the two groupswere compared.ResultsAfter treatment,GI,PD and BOP of the two groupswere improved significantly than those before treatment(P<0.05),therewas no significant difference between two groups(P＞0.05).Before treatment,there was no significant difference in score of DFS between the two groups(P＞0.05);DFS score of the experimental group after treatmentwas significantly lower than that of the control group,the difference was statistically significant(P<0.05).ConclusionBangwo magnetostrictive comprehensive therapeutic instrument can achieve effective result in treating chronic periodontitis,and reduce pain of patient,whichmakes itmore acceptable by patients. 2016 Vol. 23 (33): 114-116 [Abstract] ( 122 ) HTML (39 KB)  PDF  (0 KB)  ( 5 ) 117 Clinical observation of phacoemulsification cataract extraction in the treatment of angle-closure glaucoma WANG Hai-yan ObjectiveTo study the clinical effect of phacoemulsification in the treatment of angle closure glaucoma.MethodsEighty-two patients with angle closure glaucoma treated in our hospital from June 2014 to May 2016 were selected as the research objects.All patients were randomly divided into two groups,the study group and the control group,41 cases in each group.Patients of the control group were treated with trabeculectomy,and the study group was given phacoemulsification cataract extraction.The visual acuity,intraocular pressure,the anterior chamber depth and the adhesion and closure of angle in the two groups before and after treatmentwere compared.ResultsVision and intraocular pressure of the research group after treatment[(0.78±0.10)°,(12.39±7.60)mmHg]was better than thatbefore treatment [(0.23±0.12)°,(35.89±11.50)mmHg]and the control group after treatment[(0.56±0.07)°,(16.52±9.67)mmHg],the differenceswere statistically significant(P<0.05);the anterior chamber depth and the adhesion and closure of angle of the research group after treatment[(3.52±0.50)mm,(58.56±26.27)°]was better than that before treatment[(1.60±0.32)mm, (284.11±37.30)°]and the control group after treatment[(1.79±0.38)mm,(206.21±38.74)°],the difference was statistically significant(P<0.05).ConclusionThe phacoemulsification for patientswith angle closure glaucoma treatment is safe and reliable,with good clinical effect,and can effectively improve the visual acuity and intraocular pressure,should be widely used in clinical practice. 2016 Vol. 23 (33): 117-119 [Abstract] ( 89 ) HTML (40 KB)  PDF  (0 KB)  ( 34 ) 120 Application of Dexmedetom idine in the induction and maintenance of patientswith acute coronary syndrome ZHENGHai-tao;SU Xin-juan;HU Jie ObjectiveTo explore the safety and the effects of Dexmedetomidine on acute coronary syndrome patients during induction.Methods25 patientswith acute coronary syndromes who underwent surgery in our hospital from January to December 2015 were selected as experimental group,20 patientswith acute coronary syndromes from January to December 2014 were selected as control group.The patients in the experimental group were injected with 1μg/kg Dexmedetomidine for 15 minutes and then injected with 0.3μg/kg·h of the same volume of saline for 15 minutes,then Etomidate,Sufentanil,Vecuronium slowly induced intubation.Propofol and sufentanil were maintained by target-controlled infusion,and bispectral index (BIS)wasmaintained at 40 to 60.Blood pressure and heart rate were recorded at T1,T2,T3,and T4.Cortisol concentration wasmeasured by 3 ml blood collection.ResultsThe concentration of cortisol in experimental group was significantly lower than that of control group at T3and T4,and the heart rate at T1,T2and T3was slower than that of control group (P<0.05).Conclusion Dexmedetomidine can induce and maintain acute coronary syndrome,and the circulation ismore stable andmore effective in suppressingmyocardial stress response. 2016 Vol. 23 (33): 120-122 [Abstract] ( 115 ) HTML (36 KB)  PDF  (0 KB)  ( 32 ) 123 Clinical observation on 150 cases of epidural analgesia delivery LIU Hui-ling ObjectiveTo investigate the clinical effect of labor analgesia observed epidural anesthesia and analgesia on mother and child labor.Methods150 primiparae from April to June 2015 were selected in our hospital and had no contraindication of obsterics and anesthesia department,they would be given labor analgesia as the observation group,150 primiparaewere chosed in the same period and had no contraindication of obsterics and anesthesia department,but they would not be given labor analgesia as a control group.The rate of cesarean section,postpartum hemorrhage,the time of labor and neonatal Apgar score were compared between two groups.ResultsThe labor time and cesarean section rate of the observation group were significantly lower than those of control group,there were significant differences(P<0.05),and postpartum hemorrhage,comparing of two groupswere compared,the difference were not significant(P>0.05).ConclusionEpidural anesthesia for labor analgesia,can effectively promoted the progress of labor,ease puerpera childbirth pain,reduce the neonatal asphyxia and cesarean section rate,and has no effectonmaternal and child safety. 2016 Vol. 23 (33): 123-125 [Abstract] ( 100 ) HTML (38 KB)  PDF  (0 KB)  ( 42 ) 126 An observation of the efficacy of levonorgestrel releasing intrauterine system in the treatment of patientswith postoperative endometriosis MU Jing ObjectiveTo explore the application effect of the levonorgestrel releasing intrauterine system(LNG-IUS)on postoperative endometriosis (EMs)patients.MethodsA retrospective study wasmade of the 72 cases of patients who were diagnosed as having endometriosis and underwent laparoscopic conservative surgery from January 2015 to January 2016.They were divided into two groups according to admission time:36 cases were treated with LNG-IUS as group A, and the other 36 caseswere treated with gestrinoneas as group B.Follow-up of 6months,before and after treatment the changes of serum high sensitive C reactive protein(hs-CRP)and vascular endothelial growth factor(VEGF)were compared.ResultsThe hs-CRP of group A after treatmentwas(3.7±1.0)mg/L,the group B was(7.2±1.5)mg/L,the difference was siginificant(P<0.05);the VEGF of group A was(100.20±14.9)pg/ml,the group B was(148.5±17.5)pg/ml,both decreased significantly compared with before treatment,and compared with group B,the group A was decreased significantly,and the differenceswere significant(P<0.05).ConclusionLNG-IUS can effectively reduce the levels of inflammatory factors and vascular endothelial growth factor in patientswith endometriosis,and has achieved good therapeutic effect,which has the prospectof research and development. 2016 Vol. 23 (33): 126-128 [Abstract] ( 118 ) HTML (38 KB)  PDF  (0 KB)  ( 37 ) 129 Effectsobservation ofKetotifen Tabletscombinedwith Carbocisteine Tablets in treating the control of chronic obstructive pulmonary disease ZENGGuo-gen;XIAOCai-hong;CHEN Qi-wen ObjectiveTo explore the effects of Ketotifen Tablets combined with Carbocisteine Tablets in treating the control of chronic obstructive pulmonary disease.Methods100 chronic obstructive pulmonary disease patents from January 2015 to March 2016 of Guangzhou Integrated Traditional Chinese and Western Medicine Hospital were selected.Patients were randomly divided into treatment group and control group,and each group was 50 cases.Patients in control group were used administration Carbocisteine Tablets on the basis of cough and asthma,and patients in treatment group were given Ketotifen Tablets on the basis of control group,and administration for 6months.The blood biochemical index (hs-CRP,FIB,PaCO2and PaO2)of patients before and after treatment was observed.The lung function,6 minute walk distance,BODE score and CAT score of patients before and after treatmentwas compared.ResultsAfter treatment for 6 months,each blood biochemical index,lung function,6 minute walk distance,BODE score and CAT score of patients in treatment group were obvious better than those of control group,and the differenceswere significant(P<0.05).ConclusionKetotifen Tablets combined with Carbocisteine Tablets in treating chronic obstructive pulmonary disease has better effects in improving symptoms and controlling outbreak,which can prolong the interval time of disease onset,reduce the degree of attack,improve the lung function of patients and isworth to popularize. 2016 Vol. 23 (33): 129-131转134 [Abstract] ( 115 ) HTML (46 KB)  PDF  (0 KB)  ( 34 ) 132 Clinical effect of tacrolimus on senile hormone-resistant nephrotic syndrome LIU Gan-yan;CHEN Bang-ming;LIU Yong-fang;WANG Jin-xiang;WU Hui-xin;XU Ying;YAO Zi-rui;LIN Xue-fei ObjectiveTo explore the clinical effect of Tacrolimus in the treatment of senile steroid-resistant nephrotic syndrome.Methods78 cases of elderly patients with steroid-resistant nephrotic syndrome from January 2014 to January 2015 were selected and randomly divided into control group and observation group,with 39 cases in each group. The patients of the control group were given routine treatment combined with cyclophosphamide,and observation group were treated with conventional therapy combined with Tacrolimus.The therapeutic effects of the two groups were compared.ResultsThe levels of 24 h urinary protein,albumin and total cholesterol in elderly patientswith steroid-resistant nephrotic syndrome were significantly lower than those of control group(P<0.05).The effective rate of observation group was 89.74%,higher than that of control group(71.79%)(P<0.05).ConclusionThe combination of conventional therapy and Tacrolimus in treatment of elderly patients with steroid-resistant nephrotic syndrome has a significant clinical effect and isworthy of popularization and application in clinic. 2016 Vol. 23 (33): 132-134 [Abstract] ( 114 ) HTML (39 KB)  PDF  (0 KB)  ( 38 ) 135 Analysis of fatty acids com ponents in Fritillaria cirrhosa D.Don by GC-MS SHANWen-jing;WU Jian ObjectiveTo analyzed Fatty Acids components in Fritillaria cirrhosa D.Don by GC-MS.MethodsThe contents and chemical compositions of the Fatty Acids in Fritillaria cirrhosa D.Don were investigated and determined in this paper.Fatty oil was extracted with petroleum ether.The oil was determined by GC-MS after the preparation of the methyl esters with BF3-CH3-OH.ResultsThe experimental results showed that there were seperated 7 peaks,5 components of fatty acids in the oil of Fritillaria cirrhosa D.Don.There were Hexadecanoic acid，Octadecanoic acid，Tetradecanoic acid，Butanoic acid,Stearicacid.ConclusionThe exepriment reveals that there are some impotent fatty acids in Fritillaria cirrhosa D.Don.These results provide a theoretical basis formanagement and utilization of atty acids in FritillariacirrhosaD.Don． 2016 Vol. 23 (33): 135-136转139 [Abstract] ( 135 ) HTML (38 KB)  PDF  (0 KB)  ( 38 ) 137 The content determ ination of astragaloside in Naoxueshu Oral Liquid by HPLC WANG Qing-xue;HAN Lin ObjectiveTo establish an assay method of astragaloside in Naoxueshu Oral Liquid by HPLC.MethodsThe contentofastragaloside in Naoxueshu Oral Liauid wasdetected by HPLC,and ShimadzUVP-ODS（5μm,250mm×4.6mm）Column was used.18 alkyl bonding silica gel as the filling agent.Themobile phase was amixture of acetonitrile-water (17∶33).According to the theory of number of astragalus armor plate tower peak computation should not below 4000.ResultsA good linear relationship of Astragalosidewas in the rangeof injection volumewas from 1.78 to24.92μg(r=0.9998), the average recovery rate was 101.02%,RSD=4.03%.The constancy was good within 8 hours under common temperature.ConclusionThe HPLCmethod is convenient,sensitive and accurate.It can be amethod for quality control of Naoxueshu Oral Liquid in production. 2016 Vol. 23 (33): 137-139 [Abstract] ( 114 ) HTML (38 KB)  PDF  (0 KB)  ( 39 ) 140 Determ ination of AstragalosideⅣin Jianyaotong Granules by HPLC SUN Yong-hui;ZHAO Jing;SUN Nan ObjectiveTo establish themethod for the determination of astragalosideⅣin Jianyaotong Granules.MethodsHPLC was used the quality of astragalosideⅣ in Jianyaotong Granules,analytical column was Diamonsil C18(4.6 mm×250 mm,5μm).Mobile phase was Acetonitrile-Water(30∶70).Flow rate was 1.0 ml/min,the parameter of ELSD detector：the flow rate of N2was 2.5 L/min;the temperature of drift tube was 105℃.ResultsThe linear range of astragalosideⅣ was from 0.56 to 4.20μg(r=0.9994).The average recovery was 95.83%(RSD=1.39%,n=5).ConclusionThis method is proved to be sensitive and reliable.It can be the quality detectionmethod of Jianyaotong Granules. 2016 Vol. 23 (33): 140-142 [Abstract] ( 129 ) HTML (37 KB)  PDF  (0 KB)  ( 13 ) 143 Theexperienceof the famous TraditionalChineseMedicine Doctor ZHANG Zhaoyuan useW ulingsan to cure dizziness and cerebrovascular disease ZHU Ting-ting;GAO Si-yan Wulingsan iswidely used in clinic,but few doctors use it to treatwith dizziness and cerebrovascular disease, the famous Traditional Chinese Medicine Doctor ZHANG Zhaoyuan,has rich clinical experience of using Wulingsan to treatwith dizziness and cerebrovascular disease.This article is sharing four cases. 2016 Vol. 23 (33): 143-146 [Abstract] ( 147 ) HTML (47 KB)  PDF  (0 KB)  ( 8 ) 147 Clinical effect of Chang Yuan Zhiyi Prescription in treating infantile enuresis MIHong-tu;LIPing;LUO Zhi-zhao ObjectiveTo explore the clinical effectof Chang Yuan Zhiyi Prescription in treating infantile enuresis.Methods60 infantile enuresis patients from October 2014 to July 2016 in our hospital were selected.Patients were divided into observation group and control group according to random number table,and each group was 30 cases.Patients in control group were given Suoquan pill,and the observation group were given Chang Yuan Zhiyi Prescription thatmade in our hospital on the basis of control group.The treatment effects in two groupswere compared.ResultsAfter treatment, daytimemicturition frequency,number of nocturnal enuresis and night awakening times in observation group were less than those of control group[(1.24±0.26)times vs(2.30±0.31)times;(0.67±0.14)times vs(1.46±0.36)times and(0.76± 0.16)times vs(1.65±0.26)times](P＜0.01).The incidence rate of adverse effects in observation group during treatment was lower than that of control group[3.33%（1/30）vs 23.33%（7/30）]（P＜0.05）.The results of 2 months followed-up showed that recurrence rate in observation group was lower than that of control group[3.33%（1/30）vs 20.00%（6/30）], and the difference was statistical significance(P<0.05).ConclusionUsing Chang Yuan Zhiyi Prescription in treating infantile enuresis with effective effects,which can improve enuresis symptoms effectively,with high safety and low recurrence rate and isworth to popularize. 2016 Vol. 23 (33): 147-149 [Abstract] ( 126 ) HTML (38 KB)  PDF  (0 KB)  ( 32 ) 150 The observation of curative effect of Zusanli point acupuncture therapy combined with prickingblood?and cupping therapy on scapulohumeral periarthritis DENG Yu-ling;LIAO Qiong;LIJiao ObjectiveTo explore the therapy of acupuncture Zusanli joint sting clinical efficacy inflammation around the shoulder joint network bloodletting cupping.Methods90 patients with periarthritis from February 2014 to March 2016 treated in our hospital were randomly divided into control group 1,control group 2,observation group,30 cases in each group.The control group 1 were received bloodletting and cupping therapy based on original treatment,the control group 2 were received exercise therapy acupuncture Zusanli,observation group were received exercise therapy of acupuncture zusanli combined with local pain points bloodletting cupping,for 10 days as a course,continuous treatment of 2 courses,the effects were evaluated.ResultsThe effective rate of control group 1 was 56.67%,the control group 2 was 70.00%,the observation group was 96.67%,the difference was siginificant(P<0.05);follow-up for half a year,the control 1 group recovered was 8 cases,6 cases of recurrence,the recurrence rate was 75.00%,the control 2 recoverde was 13 cases,6 cases of recurrence,the recurrence rate was 46.00%,2 cases of the observation group recovered was 22 cases,2 cases of recurrence,the recurrence rate was 9.00%,the control group were higher than that of observation group,with differences statisticant(P<0.05).ConclusionZusanli acupoint combined with prickingblood and cup-ping therapy is a simple and effective way to treat scapulohumeral periarthritis and the clinical effect is significant.It′sworth popularized in clinic. 2016 Vol. 23 (33): 150-152转155 [Abstract] ( 134 ) HTML (42 KB)  PDF  (0 KB)  ( 28 ) 153 Clinical observation on 30 Cases of urem ic pruritus treated with Jiawei Jiedu Huoxue Decoction WU Fu-xian ObjectiveTo explore the clinical effect of Jiawei Jiedu Huoxue decoction in the treatment of uremic pruritus.Methods60 cases of uremic pruritus in our blood purification room from January 2015 to April 2016 were selected and randomly divided into the treatment group and the control group,30 cases in each group.Ppatients of two groups were given hemodialysis 2 to 3 times/week,joint blood perfusion 1 time/week,and low-salt low-fat low-phosphorus high-quality and low-protein diet,correcting acidosis and anemia,calcium,phosphorus,control blood pressure and other basic treatment,on the basis of the above treatment control group was given oral cetirizine hydrochloride 10 mg/d,the treatment group were given oral Jiawei Jiedu Huoxue decoction,the therapeutic effect of two groupswere compared.ResultsThe total effective rate of the treatment group was 90.0%,which was higher than 70.0%of the control group,difference was statistical significant(P<0.05).Before and after treatment the itch level(VASscore)of two groupswere compared,the treatment group pruritus to reduce degree was better than that of control group,the difference was significant (P<0.05).ConclusionJiawei Jiedu Huoxue decoction is effective prescription in the treatment of uremic pruritus,it is worth further research and promote the use in the clinical practice. 2016 Vol. 23 (33): 153-155 [Abstract] ( 125 ) HTML (38 KB)  PDF  (0 KB)  ( 22 ) 156 Clinical effect of Buyang Huanwu Decoction combined with Tianma Gouteng Drink treating cerebral infarction GU Feng ObjectiveTo explore the clinical effect of Buyang Huanwu Decoction combined with Tianma Gouteng Drink treating cerebral infarction.Methods90 patientswith cerebral infarction treated by our hospital from July 2014 to July 2016 were randomly divided into the control group and the observation group,each group had 45 patients.The control group was given symptomatic support treatment,intravenous infusion of Edaravone and oral Aspirin,while the observation group was added Buyang Huanwu Decoction combined with Tianma Gouteng Drink on the basis of control group. After a course treatment,the related index of NIHSS score,ethanol(ET),lipid peroxides(LPO),superoxide dismutase(SOD) and glutathione peroxidase(GSH-Px)and so on and treatmenteffect in two groupswere observed.ResultsAfter a course treatment,NIHSS score of the observation group was(7.62±2.03)points,the related index of ET,LPO,SOD and GSH-Px each index and so on in the observation group was better than that of the control group respectively(P<0.05);the total effective rate in the observation group(95.56%)was higher than that of the control group(73.33%)(P<0.05).Conclusion The clinical effect of Buyang Huanwu Decoction combined with Tianma Gouteng Drink treating cerebral infarction is remarkable,and it isworthy of promotion and application in neurology clinic. 2016 Vol. 23 (33): 156-158 [Abstract] ( 131 ) HTML (41 KB)  PDF  (0 KB)  ( 7 ) 159 Effect observation of integrated traditional Chinese and western medicine treating early inflammatory small bowel obstruction after abdom inal surgery GUAN Guo-qing;CHEN Hai-yan;HUANG Cheng-cong;HUANGQi-shan;KE Yong-guo;GONGGuo-rong ObjectiveTo study the effect of integrated traditional Chinese and western medicine treating early inflammatory small bowel obstruction after abdominal surgery.Methods86 patients with early inflammatory small bowel obstruction after abdominal surgery treated from November 2012 to November 2015 were selected.They were randomly divided into control group(n=43)and study group(n=43)according to the random number tablemethod.Control group was treated with conventional western medicine,and the study group was treated with integrated traditional Chinese and western medicine.Clinical effect,complete disappearance time of symptom and the time of exhaust recovery,eating and bowel sound recovery and hospital stay,and serum level of IL-6,TNF-αand CRP in patients between two groups was compared respectively.ResultsThe total effective rate of treatment in study group was 95.35%,while itwas 81.40%in control group,and therewas a significant difference between two groups(P<0.05).The time of exhaust recovery,eating and bowel sound recovery and hospital stay in study group was obviously shorter than that of control group,and the differencewas statistically significant(P<0.05).After the twelfth days treatment,IL-6,TNF-α,CRP levelwas obviously lower than that of control group,and the difference was statistically significant(P<0.05).ConclusionThe effect of integrated traditional Chinese and westernmedicine treating early inflammatory small bowel obstruction after abdominal surgery is remarkable,it is superior to westernmedicine treatment,and it isworthy of clinical popularization and application. 2016 Vol. 23 (33): 159-161 [Abstract] ( 115 ) HTML (37 KB)  PDF  (0 KB)  ( 23 ) 162 Experience of orthodontics resident standardization training ZHAOWei-ping Resident standardization training is an important part of medical students education after graduation.It is very important for strengthening construction of health talent team,improving quality and level ofmedical and health work.Because orthodontics is one of the important branch of oralmedicine,orthodontics resident standardization training is the important supplement of oralmedical education.In order to improve quality of orthodontics of resident standardization training,this paper analysed the characteristics of orthodontics and the difficulties of resident standardization training,and summarized the teaching experience of resident standardization training.Orthodontics resident standardization trainingmethods had been discussed from the training plan,optimizing the training content,strict standardized examination,in order to improve quality of standardized training of orthodontic residents. 2016 Vol. 23 (33): 162-164 [Abstract] ( 118 ) HTML (36 KB)  PDF  (0 KB)  ( 35 ) 165 Application effect of multimedia education in the diet education of patientswith type 2 diabetesmellitus YANG Guo-hua;WEN Yi;ZHANG Qi-ping;LIJing;ZHONGMing-mei ObjectiveTo analyze effect ofmultimedia education on diet education in patientswith type 2 diabetesmellitus.Methods120 patientswith 2 type old diabetesmellitus admitted into our hospital from May 2013 to August 2014 were randomly selected as research object and divided into two groups according to 1∶1 proportion,60 patients in control group were implemented traditional diet education mode,while 60 patients in observation group were given multimedia education based on traditional diet education mode,blood glucose levels,self-care ability score and diet knowledge score in two groups after different educationalmethods were evaluated.ResultsAfter intervention,blood glucose levels in two groups were significantly different than those before intervention (P<0.05).Fasting blood glucose and postprandial 2 h blood glucose level in the observation group was(6.0±2.3),(8.5±1.9)mmol/L,compared with(7.8±3.2), (10.2±3.6)mmol/L in the control group therewas statistical difference (P<0.05).Self-care ability scores in the observation group was superior to that in the control group;diet knowledge score in the observation group was(94.1+2.3)scores, significantly higher than(82.4+3.1)scores in the control group,and the difference was statistically significant(P<0.05).ConclusionMultimedia diet education for patients with type 2 diabetesmellitus can significantly improve the understanding of diet-related knowledge,more control blood glucose levels and has notable effect. 2016 Vol. 23 (33): 165-167 [Abstract] ( 113 ) HTML (41 KB)  PDF  (0 KB)  ( 36 ) 168 Influence of physiological rhythm on venous thrombosis associated with PICC catheterization FAN Bin;MEIGan-hong;HUANG Fen;ZHANG Yu-hong ObjectiveTo analyze the influence of physiological rhythm on venous thrombosis associated with peripherally inserted central catheterization (PICC).MethodsFrom January 2015 to June 2016,180 patients were randomly selected from patients with malignant tumor and given PICC catheterization in our hospital and they were divided into two groups according to their venous catheterization time.Under the ultrasound guidance,basilic vein or brachial vein puncture in two groups were conducted after inserting PICC tube.In the observation group (n=90), catheterization was carried out from 15:00 to 17:00,while in the control group,itwas from 8:00 to 10:00.ResultsIn the observation group,the incidence rate of phlebothrombosiswas obviously lower than that in the control group (4.44%vs 18.89%)(P<0.05),and the severity of venous thrombosiswasmilder than that in the control group (gradeⅡ1.11%vs 7.78%,gradeⅢ 0 vs 6.67%) (P<0.05).The incidence rate of complication between two groups had no statistical differenc (P>0.05).ConclusionThe incidence rate of venous thrombosis after PICC catheterization is different in different time period.In comparison of PICC catheterization performed during the low-coagulation time window(around 15:30 in the afternoon)and hypercoagulable time window (from 6:00 of early morning to noon),the former one can decrease the incidence of venous thrombosis. 2016 Vol. 23 (33): 168-170 [Abstract] ( 115 ) HTML (39 KB)  PDF  (0 KB)  ( 39 ) 171 Effect com parision and observation of whole course education and routine nursing in management of diabetes nursing DENG Ying-hui;GU Xiao-yan;ZHAO Ru-ru ObjectiveTo analyze the application effect of whole course education and routine nursing in nursingmanagement of diabetes.Methods100 patients with diabetes in accordance with the relevant standards of the study were randomly selected from January 2015 to January 2016,and according to the random number tablemethod,they were divided into observation group and control group,each group had 50 cases.In observation group,the whole course educationmodel was adopted,and control group was given the routine nursingmode.Blood glucose control rate before and after the nursing between two groups was observed.The tailor-made questionnaire was use to observe the mastering for diabetes knowledge in patients of two groups before and after the nursing between two groups.Quality life questionnaire was used to observe the change of quality life in patients of two groups before and after the nursing.The hospital rating scale of our hospitalwas used to observe the satisfaction degree for nursing in patients of two groups.ResultsTherewas no statistical difference of the rate of blood glucose control before nursing between two groups (P＞0.05).The rate of blood glucose control in observation group(68%)after nursing was significantly higher than that of control group(40%) (P<0.01).There was no statistical difference ofmastering for diabetes knowledge and quality of life score before nursing between two groups (P＞0.05).Mastering for diabetes knowledge and quality of life score after nursing in observation group [(86.9±15.2)points,(81.6±14.6)points]was significantly better than that of control group [(71.6±12.6)points, (73.5±12.5)points](P<0.01).Nursing satisfaction rate of observation group and control group was 94%,80%respectively, and there was significant difference between two groups(P<0.05).ConclusionThe whole education has better application effect in diabetes nursing management,and it can effectively improve the awareness ability of diabetes-related knowledge in patients,improve quality of life and satisfaction degree of nursing. 2016 Vol. 23 (33): 171-173 [Abstract] ( 153 ) HTML (39 KB)  PDF  (0 KB)  ( 28 ) 174 Application effect com parison of enteral immune nutrition and total nutrition therapy in postoperative nursing of patientswith gastroenteric tumor FAN Shi-yuan ObjectiveTo explore and compare the application effect of enteral immune nutrition and total nutrition therapy in postoperative nursing of patientswith gastroenteric tumor.Methods64 patientswith gastrointestinal tumor treated by our hospital from February 2013 to January 2015 were evenly and randomly divided into observation group(n=32, given enteral immune nutrition nursing after surgery)and control group(n=32,given total nutrition therapy after surgery). The physical condition,and level of serum protein (Alb),hemoglobin (Hb),and immunoglobulin G,A,and M (IgG,IgA, IgM)in different period of patients in two groupswere observed and recorded.ResultsAfter intervention,the physiological indexes including body condition index,Alb,Hb,and immunoglobulins in observation group were superior to those in control group,and there was a statistical differences(P<0.05).ConclusionPostoperative enteral immune nutrition therapy for patientswith gastrointestinal tumor can improve the organism immune and nutritional status of patients and protect their postoperative healing and quality of life. 2016 Vol. 23 (33): 174-176 [Abstract] ( 126 ) HTML (37 KB)  PDF  (0 KB)  ( 35 ) 177 Effect of different oralmotion intervention on oral feeding of premature infant TU Man-mei;XIN Ping;WANG Li-li;YU Ying LICui ObjectiveTo explore the effect of different oral motor interventions on oral feeding of premature infant.MethodsFrom January 2015 to June 2016,76 premature infants with gestational age treated by premature infant ward were selected as object in our hospital.After randomly numbering,they were evenly divided into observation group (n= 38)and control group(n=38)based on the parity of themantissa.In the control group,non-nutritional sucking intervention was carried out on the basis of routine nursing,and the observation group was given oralmassage intervention on the basis of control group.The related index of feeding progress,feeding performance,and body weight growth were compared between two groups.ResultsIn the observation group,the transition time and tube feeding time were significantly shorter than those in the control group (P<0.01).The feeding efficiency in oral initially,themilk intake ratio in oral initially,and feeding efficiency in oral completely were all remarkably higher than those in the control group(P<0.05).The bodymass in oral feeding completely was greatly higher than the latter(P=0.000).ConclusionCombination of oralmassage intervention and non-nutritive sucking intervention can significantly improve the feeding progress,feeding performance and promote body weightgrowth. 2016 Vol. 23 (33): 177-179 [Abstract] ( 129 ) HTML (39 KB)  PDF  (0 KB)  ( 32 ) 180 Effect analysis of late delivery of shoulder m idw ifery preventing shoulder dystocia and neonatal birth injury ZHU Hui-juan ObjectiveTo study the effect of late delivery of shouldermidwifery preventing shoulder dystocia and neonatal birth injuryinnatural childbirth.MethodsFrom January to September 2015,4030 caseswith natural childbirth wereselected observation group.Late delivery of shouldermidwifery was conducted:Not delivered shoulder immediately after the delivery of fetal head,butwaiting for the delivery of fetal head shoulder reseting naturally or next contraction arriving to deliver shoulder;3977 caseswith natural childbirth selected before conduction of new method to deliver from January to September 2014 were set as control group,and they were deliveried according to routine deliverymethod.The incidence rate of shoulder dystocia,neonatal clavicular fracture,brachial plexus injury,neonatal asphyxia between two groupswas compared respectively.ResultsIn the observation group,the incidence rate of shoulder dystocia(0.67%)was significantly lower than that of the control group(1.68%)(P<0.01).In the observation group,the incidence rate of neonatal clavicular fracture rate (0)waswas significantly lower than that of control group (0.15%)(P<0.05).There was no neonatal brachial plexus injury in two groups(P>0.05).The incidence rate of neonatal asphyxia in the observation group and the control group,was 0.17%,0.30%respectively,and there was no statistical difference (P>0.05).ConclusionLate delivery of shouldermidwiferycan reduce the occurrence of shoulder dystocia,and reduce the incidence rate of neonatal clavicular fracture. 2016 Vol. 23 (33): 180-182转182 [Abstract] ( 140 ) HTML (41 KB)  PDF  (0 KB)  ( 30 ) 183 Research of psychological assessment tool in patients with surgery before operation and application effect CHEN Yan-hui;YIHong-yan;PENG Yan-mei ObjectiveTo explore the application method and effect of"psychological assessment tool in patients with surgery before operation".Methods1000 patientswith surgery treatment treated by Shajing People′s Hospital of Baoan District in Shenzhen City from January to June 2015 were selected as study object.Self-rating anxiety scale,trait anxiety questionnaire and“psychological assessment tool in patientswith surgery before operation”was used respectively to evaluate the anxiety degree of patients and the reliability and validity analysis was conducted,and all data were analyzed and treated statistically.ResultsThe scoreand the total score′s correlation reached a significant level,the correlation coefficientwas above 0.4;Cronbach alpha coefficientwas 0.809,the split half reliability was 0.863,the test-retest reliability was 0.611,and the self-rating anxiety scale of all factorswere significantly correlated,correlation coefficientwas from 0.162 to 0.603;"preoperative anxiety evaluation table and the total score of trait anxiety questionnaire were significantly correlated,the correlation coefficient was from 0.290 to 0.371.ConclusionRevised"preoperative anxiety evaluation scale"has good reliability and validity,provides the evaluation index and reference basis for assessment of preoperative anxiety,and it isworthy of clinicalwide promotion and application. 2016 Vol. 23 (33): 183-185 [Abstract] ( 120 ) HTML (37 KB)  PDF  (0 KB)  ( 7 ) 187 Nursing demands investigation of em pty nest elderly patientswith chronic disease and research of im p lementation holistic nursing HUANG Dong-ying ObjectiveTo understand the health status of the empty nest elderly patientswith chronic disease and its demand for community nursing,and to evaluate the effect of implementation of holistic nursing.MethodsFrom June 2014 to May 2016,1016 empty nest elderly patientswith chronic disease of three communities extracted in Sanxiang Town of Zhongshan City were given questionnaire investigation by systematic training of investigator.3 above-mentioned communitieswere selected as observation group,and holistic nursing intervention was conducted for 3months,while the other community(497 empty nest elderly patientswith chronic disease)were selected as control group at the same period, and any nursing intervention was done during study period.ResultsChronic disease of empty nest elderly patients with chronic disease in the top 5 was hypertension(31.3%),diabetes(28.3%),coronary heart disease(18.9%),COPD(18.3%) and chronic gastrointestinal disease (17.4%)respectively.The demand for community nursing services in the top 3 was provide on-site service when illness,prevention and treatment and nursing of chronic disease and first aid knowledge and nursing.Integrated nursing intervention for 3months,the hospitalization rate of patients in observation group was obviously lower than that in control group,and the differencewas statistical significance (P<0.01).ConclusionImplementation of holistic nursing intervention can enhance daily life ability of empty nest elderly patients with chronic disease and decrease hospitalization rate. 2016 Vol. 23 (33): 187-188 [Abstract] ( 121 ) HTML (35 KB)  PDF  (0 KB)  ( 21 ) 189 Influence of collaborative nursing on limb function and psychological status in patientswith hem iplegia after cerebral infarction CHEN Xiao-ling ObjectiveTo investigate the influence of collaborative nursing on limb function and psychological status in patientswith hemiplegia after cerebral infarction.Methods80 caseswith hemiplegia after cerebral infarction treated by our hospital from January 2013 to March 2015 were randomly divided into two groups according to the random number method,and each group had 40 cases.The observation group were given collaborative nursing,while the control group was given routine nursing.The improvement of bad life habits after intervention in patients between two groups was compared.European stroke score(ESS),improved Barthel index and change of Fugl-Meyermotor function and change of anxiety and depression was counted respectively.ResultsAfter intervention,the ratio of still smoking,drinking,high-salt eating and staying up in the observation group were lower than those of control group (P<0.01),after intervention,ESS, Barthel index and Fugl-Meyer score in the observation group were lower than pre-intervention and post-intervention of control group (P<0.05).After the intervention,the HAMD and HAMA score in the observation group were lower than pre-intervention and post-intervention of control group (P<0.05).ConclusionCollaborative nursing can effectively improve the bad habitswith hemiplegia after cerebral infarction,and improve the treatment effect,reduce the incidence of anxiety and depression. 2016 Vol. 23 (33): 189-191转194 [Abstract] ( 155 ) HTML (42 KB)  PDF  (0 KB)  ( 42 ) 192 Effect of heat preservation nursing on the intraoperative stress of patients in operating room HU Dan ObjectiveTo investigate the effect of heat preservation nursing on the intraoperative stress of patients in operating room.MethodsA total of 220 surgical patients treated by our hospital from January 2014 to January 2016 were collected as objects.All patientswere randomly divided into control group(110 patients)and observation group(110 patients)using the random numbermethod.The control group was given routine nursing,while the observation group was given heat preservation nursing on the basis of control group.The intraoperative stress of the patients between the two groupswas compared.ResultsNo significant difference was observed in basal body temperature of the patients between two groups,aswell as the the temperature after 10min anesthesia(P>0.05).The temperature after 20min operation were significantly decreased in control group (P<0.01).The control of blood pressure,the level of NE,E and heart rate in the observation group are significantly better than those in the control group (P<0.01).ConclusionThe heat preservation nursing can effectively control the temperature of the patients,prevent the patients from intraoperative hypothermia cases,reduce the adverse effect caused by the sympathetic nervous excitement,and alleviate intraoperative stress response. 2016 Vol. 23 (33): 192-194 [Abstract] ( 103 ) HTML (37 KB)  PDF  (0 KB)  ( 27 ) 195 Analysis of clinical nursing in chemotherapy treatment of cervical cancer by Paclitaxel combined with Cisp latin TU Xiao-juan ObjectiveTo explore the clinical nursing methods of Paclitaxel combined with Cisplatin chemotherapy in the treatment of cervical cancer.MethodsClinical data of 60 patients with cervical cancer in our hospital from June 2014 to June 2015 were retrospectively analyzed,according to the nursingmethods they were divided into experimental group and control group,each of 30 cases,they were treated with Paclitaxel combined with Cisplatin,patients in the intervention group were received the routine nursing care,observation group on the base of control group were received comprehensive nursing intervention.After nursing,SAS scores and SDS scores of two groupswere compared.ResultsThe SAS scores and SDS scores in the observation group were significantly lower than those of the control group,the differences were significant(P<0.05).The overall satisfaction rate of observation group was significantly higher than that of control group,the difference was significant(P<0.05).ConclusionThe nursing intervention can effectively improve the psychological status of patients with cervical cancer,improve patients'satisfaction,the effect is significant,and can be promoted in the chemotherapy of cervical cancer patients. 2016 Vol. 23 (33): 195-197 [Abstract] ( 119 ) HTML (37 KB)  PDF  (0 KB)  ( 34 )

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