微造瘘经皮肾镜吸引取石术后血降钙素原、白介素-6、内毒素鲎变化研究

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Abstract ObjectiveTo explore the changes of procalcitonin(PCT),interleukin-6 (IL-6)and endotoxin limulus after suctioningmini-percutaneous nephrolithotomy(SMPCNL).Methods122 patients with percutaneous nephrolithotomy indications in our hospital from July 2014 to July 2015 were selected as study object,no surgical contraindications. According to odd and even numbers of admission time,patients were divided into two group,patients in SMPCNL group was given SMPCNL,with a total of 62 cases;patients in traditionalmini-percutaneous nephrolithotomy (MPCNL)group were given MPCNL,with no negative pressure suction,a total of 60 cases.The levels of PCT,IL and endotoxin limulus weremeasured and compared before and after operation for 1 day.ResultsThe level of PCT,IL-6 and endotoxin limulus was(0.056±0.011)ng/ml,(5.4±3.9)pg/ml and (0.56±0.34)EU/ml respectively in SMPCNL group before operation,with (0.336±0.230)ng/ml,(6.9±4.5)pg/ml,(1.68±0.57)EU/ml respectively after operation for 1 day;and the levels of PCT,IL-6 and endotoxin limuluswas(0.050±0.021)ng/ml,(5.2±4.1)pg/ml,(0.55±0.27)EU/ml respectively in MPCNL group before operation,with (3.652±1.680)ng/ml,(8.9±5.6)pg/ml,(3.27±2.12)EU/ml respectively after operation for 1 day,there was no significant difference in PCT,IL-6 and endotoxin limulus value between two groups before operation(P>0.05); serum PCT,IL-6,endotoxin limulus values in two groups after operation for 1 day was higher than that before operation (P<0.05);serum PCT,IL-6 and endotoxin Limulus value in the SMPCNL group after operation for 1 day was lower than that in the MPCNL group after operation for 1 day,and the difference was statistically significant(P<0.05).ConclusionSerum PCT,IL-6 and endotoxin limulus concentration are good indicators formonitoring percutaneous nephrolithotomy as an indicator of inflammatory reaction.Inflammatory response after SMPCNL is lower than that of MPCNL.

Key words： Mini-percutaneous nephrolithotomy Procalcitonin Interleukin-6 Endotoxin Limulus

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	Articles by authors
	DU Chuan-ce
	WU Xiao-yuan
	SONG Le-ming
	LIQi-shan

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DU Chuan-ce,WU Xiao-yuan,SONG Le-ming, et al. Change study of blood procalcitonin,interleukin-6,endotoxin Limulus after m ini-percutaneous nephrolithotom y[J]. 中国当代医药, 2016, 23(33): 56-58.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2016/V23/I33/56

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