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2019 Vol. 26, No. 27
Published: 2019-09-28
 
 
7 Study on boiling and dispersing technology of Tongbi Huoluo Decoction
ZHU Wei-xing;ZHANG Min; GAN Guo-xing; LONG Guo-bin; YU Wen-xin
Objective To explore the decoction technology of Tongbi Huoluo Decoction.Methods The content of osthole and paeoniflorin in Tongbi Huoluo Decoction were determined by high performance liquid chromatography (HPLC)with XBridge C18 column,acetonitrile-water (49：51) as mobile phase,detection wavelength at 330,230 nm and column temperature at room temperature of 25℃.The contents of total solids and index components were used as evaluation indexes,and orthogonal test was used to screen the decoction process.By comparing the quality of decoction with that of traditional decoction pieces,the dosage of decoction was screened.Results Ostholewas in the range of 0.1224-4.0800 μg,with a good linear relationship (r=0.9999),the average recovery rate was 101.14%,RSD was 1.42%.Paeoniflorin has a good linear relationship in the range of 0.8194-16.3880 μg (r=0.9999),with an average recovery of 99.55% and RSD of 1.79%.The best decocting process was to add 12 times of water,soak for 5 min,decocting for 20 min each time,and decocting once.Through screening the clinical recommended dose test of decoction,the decoction dose equivalent to 35% of the traditional decoction pieces of Tongbi Huoluo Decoction was selected as the clinical recommended dose.Conclusion The optimized decocting process is simple,rapid,stable and feasible,and the selected dosage can provide guidance for clinical application.
2019 Vol. 26 (27): 7-11 [Abstract] ( 392 ) HTML (41 KB)  PDF  (0 KB)  ( 19 )
12 Meta-analysis on the effect of blood glucose control and behavior management in patients with type 2 diabetes using mobile App
LUO Sha; LI Jun-wen; CAO Lu-lu; WEN Yi3;YANG Jun
Objective To comprehensively evaluate the effectiveness of applying mobile App on blood glucose control and behavior management in patients with type 2 diabetes in foreign countries by using Meta-analysis.Methods PubMed,Cochrane Library,Web of Science,OVID,MEDLINE,EMBASE with the keywords as “type 2 diabetes/T2DM,mobile health/telehealth/mHealth/smartphone,App/application,and self-management” were searched.The literature retrieving from these databases were limited to April 28,2018.Revman 5.3 software was used for statistical analysis.Results A total of 13 studies were included with the involvement of 1217 subjects.Meta-analysis showed that the hemoglobin A1c(HbA1c) level was significantly improved after the intervention of the mobile App in the observation group (MD=-0.41,95% CI： -0.56： -0.25,P＜0.000 01).Mobile App had a good effect on patient diet management (MD=1.58,95%CI：0.26-2.90,P=0.02).In terms of patient′s exercise management and medication compliance,the effect of the mobile App was not superior to regular care (MD=0.49,95%CI： -0.97-1.94,P=0.51;MD=-0.31,95%CI： -2.10-1.49,P=0.74).Subgroup analysis showed that the HbA1c levels in the observation group were significantly lower than those in the control group after 3,6,9,and 12-month intervention (P＜0.05),and there was no statistical difference between the different durations of intervention (P＞0.05).Conclusion Mobile App intervention can effectively improve glycosylated hemoglobin levels in patients with type 2 diabetes,but the duration of intervention has no effect on glycemic control.The mobile App improves patients′ diet management but has no obvious advantage in exercise and medication.
2019 Vol. 26 (27): 12-16 [Abstract] ( 529 ) HTML (44 KB)  PDF  (0 KB)  ( 16 )
17 Study on applicability test of microbial limit test method for Fukang Gel
GAN Can-yun; CHEN Hai-hong; YANG Hai-yan
Objective To establish a suitable microbial limit test method for Fukang Gel.Methods According to the 4 general principles 1105,1106,and 1107 of Chinese Pharmacopoeia 2015 edition,routine method and medium dilution method were used respectively to verify the microbial limit test of Fukang Gel.The recovery rates of five test bacteria,Staphylococcus aureus,Pseudomonas aeruginosa,Bacillus subtilis,Candida albicans and Aspergillus niger were used as indicators,the total number of Aerobic bacteria,Fungi and Yeasts was investigated,and the detection methods of Staphylococcus aureus and Pseudomonas aeruginosa were established.Results The total number of Aerobic bacteria counted by conventional plate method showed that the recovery rates of Staphylococcus aureus and Pseudomonas aeruginosa were low,which were not in the range of 0.5-2.0 stipulated in the Pharmacopoeia and did not meet the requirements.The total number of Aerobic bacteria counted by medium dilution method showed that the recovery rates of Staphylococcus aureus,Pseudomonas aeruginosa,Bacillus subtilis,Candida albicans and Aspergillus niger all met the requirements.The average recoveries of Candida albicans and Aspergillus niger counted by the total number of fungi and yeasts by plate method and medium dilution method were within the range of 0.5-2.0 prescribed in the Pharmacopoeia,which met the requirements.Two kinds of control bacteria were not detected in the test solution group and negative group by routine method.Staphylococcus aureus was not detected in the test group,Pseudomonas aeruginosa could be detected,and there was interference of bacteriostasis,so the method was not feasible.Pseudomonas aeruginosa and Staphylococcus aureus could be detected in the test group by medium dilution method.Both the test solution group and the negative control group showed negative,no interference,and the method was feasible.The results of three batches of samples validation showed that the total number of Aerobic bacteria,Fungi and Yeasts were in accordance with the standard,but Staphylococcus aureus and Pseudomonas aeruginosa were not detected.Conclusion Fukang Gel can be used for microbial limit test by medium dilution method.
2019 Vol. 26 (27): 17-21 [Abstract] ( 335 ) HTML (41 KB)  PDF  (0 KB)  ( 14 )
22 Research advances in indications and treatment timing of continuous renal replacement therapy in critically ill patients
LI Ji; CHEN Xiao-lan; ZHANG Xiao-ming; LI Yang-ping; MA Feng; BAI Ming
Acute kidney injury (AKI) is one of the common complications of critically ill patients.The incidence rate of AKI patients requiring renal replacement therapy (RRT) has increased significantly in recent years.For patients with hemodynamic instability,continuous renal replacement therapy (CRRT) is the most commonly used RRT mode.At present,although some clinical studies have conducted in-depth discussions on the treatment indications and timing of initiation and discontinuation for CRRT,there are still some controversies on some results.This article reviews the research advances of treatment indications timing of initiation and discontinuation for CRRT in critically ill patients,so as to provide important information for clinical work and clinical research related to CRRT.
2019 Vol. 26 (27): 22-25 [Abstract] ( 325 ) HTML (39 KB)  PDF  (0 KB)  ( 16 )
26 Research advances in the epidemiology of childhood obesity in China
ZHOU Fang-yi
In recent years,the incidence rate of childhood obesity has been increasing in all regions of China.Childhood obesity affects the development and health of children,causes the dysfunction of brain,the body′s multiple systems and multiple organ functions,and also increases the incidence of multiple chronic diseases (such as hypertension,coronary heart disease,diabetes,etc.) in adulthood.Therefore,it is very important to analyze the epidemiological characteristics of childhood obesity for the prevention of childhood obesity.In this paper,the etiology of childhood obesity in China and the incidence in different regions were reviewed to provide a theoretical basis for future research on childhood obesity.
2019 Vol. 26 (27): 26-29 [Abstract] ( 279 ) HTML (41 KB)  PDF  (0 KB)  ( 8 )
30 Research progress of nasal feeding for stroke
ZHANG Hong-bin; ZHENG Mei
Because stroke patients are prone to dysphagia,some stroke patients need to undergo nasal feeding.This article studies the effect of nasal feeding on the rehabilitation process of stroke patients with dysphagia from the following aspects,such as the methods of catheterization,depth,fixation,pre-feeding evaluation,nasal feeding related treatment methods,nasal feeding position,nasal feeding time,nutritional preparations,nasal feeding temperature,quantity,speed,time and interval time,complications,effective standards,etc.The use of nasal feeding in stroke patients with dysphagia is very common.To improve the quality of nursing services,reduce the incidence of complications,and improve satisfaction of patients,the methods of catheterization,insertion depth,fixation methods,assessment,treatment methods,posture,time,and preparation during nasal feeding must be paid attention to improve the operating techniques of nasal feeding.For common complications in nasal feeding,this article also combes and reviewes the solutions.The aim of this article is to improve the effect of nasal feeding and to summarize the experience of nasal feeding in the nursing of patients with dysphagia in stroke.
2019 Vol. 26 (27): 30-34 [Abstract] ( 302 ) HTML (63 KB)  PDF  (0 KB)  ( 19 )
35 Effect of lactobacillus intervention on expression of α -synuclein in Parkinson′s disease rats
ZHANG Ping;SHAO Liang;CAI Xin-yong;XIAO Bin;MEI Song-bei
Objective To investigate the effect of lactobacillus intervention on the expression of α-synuclein in rats with Parkinson′s disease.Methods A total of 50 SD rats were selected as subjects to establish an animal model of Parkinson′s disease,and randomly divided into control group and observation group,25 rats in each group.The control group was treated with normal saline,while the observation group was treated with lactic acid bacteria.The expression of α-synuclein,interleukin-6 (IL-6),interleukin-1β (IL-1β),and tumor necrosis factor-α (TNF-α) in the two groups were observed.Results The expression level of α-synuclein in the observation group was lower than that in the control group,with statistically difference (P<0.05).Before intervention,serum IL-6,IL-1β,TNF-α in the control group and the observation group showed no significant difference (P＞0.05).At 2 weeks after intervention,IL-6,IL-1β,TNF-α were lower in both groups than before intervention and the observation group was lower than the control group,the differences were statistically significant (P<0.05).Conclusion The application of lactic acid bacteria can reduce the level of α-synuclein in rats and inhibit its expression,but whether it can promote its reverse transmission from the intestine to the brain still needs to be further explored.
2019 Vol. 26 (27): 35-37 [Abstract] ( 310 ) HTML (31 KB)  PDF  (0 KB)  ( 15 )
38 Detection and correlation analysis of cadmium in rabbit blood，synovium，cartilage and subchondral bone
MA Xiang-hui;LI Ming;GUO Lei
Objective To study the content and correlation of cadmium in blood,synovium,cartilage and subchondral bone of rabbits after drinking water with cadmium gradually.Methods Twenty-eight New Zealand white rabbits (equal proportion of male to female) aged two and a half months old,were randomly selected from female and male groups alternatively.They were divided into control group and experimental group,14 rabbits in each group.They were fed in every single cage.In the control group,rabbits were fed with normal drinking water,and in the experimental group,they were fed with water containing 40 mg/L cadmium chloride.After three months,all rabbits were sacrificed.The cadmium content in the specimens was determined by atomic absorption spectrometry.Results The cadmium content in the blood,synovium，cartilage and subchondral bone of the experimental group was significantly higher than that of the control group (P<0.05).The cadmium content of the articular cartilage in the experimental group was positively correlated with the cadmium content in the subchondral bone,synovium and blood (r=0.959,0.556,0.942;P<0.05),respectively.ConclusionChronic poisoning of drinking water containing cadmium can cause cadmium accumulation in blood,synovium,articular cartilage and subchondral bone.Cadmium in articular cartilage is derived from subchondral bone,synovium,and blood,but mainly from subchondral bone.Cadmium accumulates in these tissues and may eventually lead to osteoarthritis.
2019 Vol. 26 (27): 38-40 [Abstract] ( 283 ) HTML (32 KB)  PDF  (0 KB)  ( 16 )
41 Effect of Tifentai on secretion of HBsAg in 2.2.15 cells
XIAO Jin-xin;YAN Yun;DU Li-bo;YU Xiu-lan;CHEN De-sheng;PAN Yu-jie
Objective To explore the effect of Tifentai (TFT) on secretion of Hepatitis B surface antigen (HbsAg) in 2.2.15 cells.Methods Hepatitis B virus deoxyribonucleic acid (HBV-DNA) clones were used to transfect human hepatoma cells HepG2 2.2.15 cell line as experimental model,and TFT was prepared into 102,51,25.5 μm solution.Lamivdine (LAM) 218 μm positive control group (referred to as LAM 218 μm group) and virus control group were established,and they were added to 24-well cell culture plates,0.6 ml/well,4 wells per concentration.The solution was changed once every 4 days,and the cell supernatant was collected on the eighth day.The titer of HBsAg in the cell supernatant was determined by enzyme-linked immunosorbent assay (ELISA),and the OD values of the three batches in each group were compared,and the average inhibition rate was recorded.Results The OD value of the LAM 218 μm group was significantly lower than that of the virus control group,and the difference was statistically significant (P<0.05).The OD values of the TFT 102,51,and 25.5 μm group were significantly lower than those of the virus control group,and the differences were statistically significant (P<0.05).The average inhibition rates of the LAM 218 μm,TFT 102,51,and 25.5 μm group were 37.49%,56.26%,47.33%,and 36.82%,respectively.Conclusion TFT can effectively inhibit the secretion of HBsAg,thereby exerting its anti HBV effect,and can provide data support and reference for further research and development of TFT to become a new anti-HBV drug.
2019 Vol. 26 (27): 41-43 [Abstract] ( 264 ) HTML (31 KB)  PDF  (0 KB)  ( 16 )
44 Study on quality standard of Corydalis Rhizoma Chewable Tablets
JIANG Li;ZHAO Sen;JI Kai-yi;ZOU Ming;SUN Yong-jin;XU Bao-li
To establish thin layer and high performance liquid phase determination methods for Corydalis Rhizoma Chewable Tablets.Methods The silica gel G plate was prepared with 1% NaOH,and the Corydalis Rhizoma Chewable Tablets were identified by tetrahydropalmatine,with n-hexane-chloroform-methanol (7.5：4：1) as the developing agent.It was determined by reversed phase high performance liquid chromatography (RP-HPLC).The column was Hypersil BDS C18 (5 μm,4.6 mm×150 mm),the mobile phase was methanol-0.1% phosphoric acid (pH adjusted to 6.0 with triethylamine) (60：40),and the detection wavelength was 280 nm.Results The thin layer of Corydalis Rhizoma Chewable Tablets was identified and placed under ultraviolet light (365 nm).In the chromatogram of the test sample,the same color fluorescent spot was displayed at the same position as the reference substance,and the negative control did not have this spot.The content of tetrahydropalmatine in the Corydalis Rhizoma Chewable Tablets was determined by HPLC.The linear range of tetrahydropalmatine was 0.0832-0.4160 μg,r=0.9997,and the average recovery rate was 99.94% (RSD=0.52%).Conclusion The qualitative and quantitative quality control methods of the Corydalis Rhizoma Chewable Tablets are easy to operate with good reproducibility and high specificity,and can be used as quality control methods.
2019 Vol. 26 (27): 44-46-50 [Abstract] ( 222 ) HTML (34 KB)  PDF  (0 KB)  ( 15 )
47 Clinical effect of Tiotropium Bromide combined with Salmeterol and Fluticasone Inhalation in the treatment of silicosis complicated with chronic obstructive pulmonary disease
LI Ming;ZHANG Zu-hua
Objective To investigate the clinical efficacy of Tiotropium Bromide combined with Salmeterol and Fluticasone Inhalation in the treatment of silicosis complicated with chronic obstructive pulmonary disease.Methods From January 2017 to October 2018,60 patients with silicosis and chronic obstructive pulmonary disease in stable stage treated in Ping Ming General Hospital of Pingxiang City in Jiangxi Province were selected.They were divided into the control group,the observation group and the treatment group according to random number table methods.The control group was given symptomatic treatment,while the observation group was given Tiotropium Bromide Powder inhalation on the basis of the above treatment.On the basis of the observation group,the treatment group received regular inhalation of Salmeterol and Roticasone Inhalation.After 3 months,all subjects completed lung function detection again,such as forced vital capacity (FVC),forced expiratory volume (FEV1),FEV1/FVC,the percentage of forced expiratory volume in the first second to the normal predicted value (FEV1%),and the walking distance of the 6-minute walking test was measured.Results The results of FVC,FEV1,FEV1/FVC,FEV1% and 6-minute walking test in the treatment group after intervention were higher than those in the observation group and the control group,the differences were statistically significant (P＜0.05).The results of FVC,FEV1,FEV1% and 6-minute walking test in the observation group after intervention were higher than those in the control group,the differences were statistically significant (P＜0.05).Conclusion Tiotropium Bromide combined with Salmeterol and Fluticasone Inhalation is effective in the treatment of silicosis complicated with chronic obstructive pulmonary disease.The pulmonary function of patients recovers better.The walking distance of 6-minute walking test is longer,which can be used as the optimal treatment.
2019 Vol. 26 (27): 47-50 [Abstract] ( 263 ) HTML (39 KB)  PDF  (0 KB)  ( 18 )
51 Clinical effct of Dandelion and Second-generation Cephalosporin in the treatment of early acute mastitis
CAI Yu-feng
Objective To explore the clinical efficacy of Dandelion and Second-generation Cephalosporin in the treatment of early acute mastitis.Methods A total of 120 outpatients and emergency patients from department of obstetrics and gynecology of the First Affiliated Hospital of Gannan Medical University from May 2017 to November 2018 were selected.They were randomly divided into the experimental group (60 cases) and the control group (60 cases) according to the digital lottery method.The experimental group was treated with Dandelion combined with Second-generation Cephalosporin (Cefuroxime Sodium),while the control group was treated only with Second-generation Cephalosporin(Cefuroxime Sodium).Both groups were treated for one week.The therapeutic effect and the time of body temperature returning to normal were compared between the two groups.Serum white blood cell count (WBC) and neutrophil count(NEUT) in the two groups were measured before and after treatment.Results The treatment effect of the treatment group was better than that of the control group,the difference between the two groups was statistically significant(P＜0.05).The temperature recovery time of the treatment group was obviously shorter than that of the control group (P＜0.05).The level of WBC and NEUT in the two groups after treatment had decreased significantly compared with that before treatment (P＜0.05),and the level of WBC and NEUT in the treatment group were significantly lower than those in the control group (P＜0.05).There were no obvious adverse reactions in both groups.Conclusion Dandelion combined with Second-generation Cephalosporin is effective in the treatment of early acute mastitis.
2019 Vol. 26 (27): 51-53 [Abstract] ( 346 ) HTML (33 KB)  PDF  (0 KB)  ( 13 )
54 Clinical effect of acupuncture at Baliao point combined with electroacupuncture in the treatment of neurogenic bladder
ZHU Yong-feng;CHENG Jun;SHAO Feng
Objective To investigate the clinical effect of acupuncture at Baliao point combined with electroacupuncture in the treatment of neurogenic bladder.Methods A total of 50 patients with neurogenic bladder from April 11,2017 to December 1,2018 were selected as the subjects,and divided into two groups by dynamic random method,with 25 patients in each group.The two groups were treated routinely.On the basis of those,the control group received nerve electrical stimulation,and the observation group was treated with acupuncture at Baliao point combined with electroacupuncture.The urination,quality of life,adverse events and patients′ satisfaction were compared between the two groups.Results After treatment,the number of urination,the number of urine leakage,and the residual urine volume in the observation group were less than those in the control group,and the amount of spontaneous urination was more than that in the control group,and the differences were statistically significant (P<0.05).There was no statistically different in total adverse events rate between the two groups (P>0.05).After treatment,the quality of life score in the observation group was (82.87±4.25) points,which was higher than that in the control group for (75.06±3.98) points,and the difference was statistically significant (P<0.05).The total satisfaction probability of the observation group (100.00%)was higher than that of the control group (76.00%),and the difference was statistically significant (P<0.05).Conclusion Acupuncture at Baliao Point combined with electroacupuncture is effective in the treatment of neurogenic bladder,which can effectively control the disease,and is worthy of clinical promotion.
2019 Vol. 26 (27): 54-56 [Abstract] ( 245 ) HTML (34 KB)  PDF  (0 KB)  ( 16 )
57 Clinical application effect comparison of expanded sponge,gelatin sponge tamponade and expanded sponge tamponade alone after endoscopic sinus surgery
CHEN Sheng-wei;CHEN Wei-dong;LIN Chu-biao;FANG Zhong-hong
Objective To investigate the clinical application effect of expanded sponge,gelatin sponge packing and expanded sponge packing alone after endoscopic sinus surgery.Methods From June 2017 to August 2018,80 patients treated in our hospital after endoscopic sinus surgery were selected as the research objects,and were divided into observation group (40 cases) and control group (40 cases) by double-color ball random grouping method.Patients in the observation group were stuffed with expanded sponge and gelatin sponge,while patients in the control group were stuffed with expanded sponge.Two groups of patients were compared in terms of various filling indexes (visual analogue scale [VAS]score of nasal cavity 24 h after operation,amount of bleeding during filling,amount of bleeding during extraction of nasal packing,difficulty in extraction of nasal packing),subjective pain score(sleep disorder,headache,nasal obstruction and nasal obstruction) and degree of nasal mucosa swelling.Results There was no significant difference in nasal cavity VAS score between the two groups at 24 h after operation (P>0.05).The bleeding volume of patients in the observation group during the filling period and the bleeding volume when nasal packing was extracted were both less than those in the control group,and the difficulty degree score when nasal packing was extracted was lower than that in the control group,the differences were statistically significant (P<0.05).The sleep disorder,headache,nasal obstruction and nasal obstruction scores of the patients in the observation group were lower than those in the control group,and the differences were statistically significant (P<0.05).The swelling degree of nasal mucosa in the observation group was lighter than that in the control group,and the difference was statistically significant (P<0.05).Conclusion Expanded sponge combined with gelatin sponge nasal packing has high application value after endoscopic sinus surgery,and can relieve patients′ subjective pain,which is worthy of clinical application and promotion.
2019 Vol. 26 (27): 57-60 [Abstract] ( 242 ) HTML (36 KB)  PDF  (0 KB)  ( 4 )
61 Comparison of the application effect of modified walking test and 6-minute walking test in patients with moderate to severe COPD of stable phase
ZHONG Yi-hua;WEN Yue-xiu;YI Na;LIU Xiao-xia
Objective To compare the application effect of modified walking test and 6-minute walking test in patients with moderate to severe chronic obstructive pulmonary disease (COPD) of stable phase.Methods Forty patients with moderate to severe COPD of stable phase in Ganzhou State Hospital of Jiangxi Province from July 2017 to July 2018 were selected as the study subjects as the study subjects,they were divided into control group and observation group according to different monitoring methods,with 20 cases in each group.The control group was given 6 minutes walking test,while the observation group was given improved walking test.The blood oxygen saturation (SpO2),heart rate (HR),respiratory rate (RR),diastolic blood pressure (DBP),systolic blood pressure (SBP),6-minute running distance,British MRC dyspnea index (mMRC),respiratory function Borg scale (Borg) and the incidence of adverse events were compared between the two groups.Results There were no significant differences in SpO2,HR,RR,DBP,SBP and 6-minute walking distance between the two groups(P>0.05).There was no significant difference in Borg score between the two groups(P>0.05).The mMRC score of the observation group was lower than that of the control group,the difference was statistically significant (P<0.05).The total incidence rate of adverse events in the observation group was lower than that in the control group,the difference was statistically significant (P<0.05).Conclusion The effect of modified walking test and 6-minute walking test in patients with moderate or severe COPD in stable stage is comparable,but the modified walking test reduces the degree of dyspnea and the incidence of adverse events.The appropriate intervention methods can be selected according to the specific conditions.
2019 Vol. 26 (27): 61-63 [Abstract] ( 266 ) HTML (34 KB)  PDF  (0 KB)  ( 14 )
64 Clinical effect of hemoperfusion combined with Cyclophosphamide and Ambroxol on paraquat poisoning
CHEN Qun-yan;HUANG Shu-wei;LIANG Juan-qing;LIU Jiong
Objective To explore the clinical effect of hemoperfusion combined with Cyclophosphamide and Ambroxol on paraquat poisoning.Methods A total of 92 patients with paraquat poisoning admitted to our hospital from January 2017 to January 2019 were enrolled,they were divided into observation group (46 cases) and the control group (46 cases) according to the computer randomization method.The observation group was treated with hemoperfusion combined with Cyclophosphamide and Ambroxol.The control group was treated with hemoperfusion combined with Cyclophosphamide.Laboratory parameters,incidence of acute respiratory distress syndrome (ARDS),and treatment outcome were compared between the two groups.Results The levels of white blood cells,serum creatinine,alanine aminotransferase and serum creatine kinase in the observation group were lower than those in the control group,the differences were statistically significant (P<0.05).The incidence of ADRS in the observation group was lower than that in the control group,the difference was statistically significant (P<0.05).The treatment survival rate of the observation group was higher than that of the control group,the difference was statistically significant (P<0.05).Conclusion Hemoperfusion combined with Cyclophosphamide and Ambroxol in the treatment of paraquat poisoning can regulate the level of leukocyte,creatinine,alanine aminotransferase and creatine kinase in patients,reduce the incidence of ARDS and improve the survival rate of patients,which is worthy of clinical application.
2019 Vol. 26 (27): 64-66 [Abstract] ( 203 ) HTML (33 KB)  PDF  (0 KB)  ( 14 )
67 Analysis the feasibility of rehabilitation training for motor dysfunction of children with cerebral palsy
GU Li-mei;YE Zhi-wei;CHEN Xiao-ling;PAN Jie;ZHOU Bing-feng
objectiveTo analyze the feasibility of rehabilitation training for motor dysfunction of children with cerebral palsy.Methods Fifty children with cerebral palsy admitted to our hospital from October 2017 to February 2019 were selected as the research objects,they were divided into observation group (25 cases) and control group (25 cases) according to random number table method.The control group was treated with acupuncture and moxibustion,while the observation group was treated with rehabilitation training on the basis of the control group.The ADL score,GMFM score,WeeFIM score and clinical therapeutic effect of the two groups were compared before and after treatment.Results The ADL score of the observation group after treatment was higher than that of the control group,the difference was statistically significant (P<0.05).The GMFM score of the observation group after treatment was higher than that of the control group,the difference was statistically significant (P<0.05).The WeeFIM score of the observation group was higher than that of the control group after treatment,the difference was statistically significant (P<0.05).The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).Conclusion Rehabilitation training can improve the daily living ability,functional independence and gross motor function of children with motor dysfunction of cerebral palsy.It has a definite therapeutic effect and is worthy of clinical promotion.
2019 Vol. 26 (27): 67-69 [Abstract] ( 237 ) HTML (32 KB)  PDF  (0 KB)  ( 15 )
70 Clinical effect of inhaled corticosteroid combined with Tiotropium Bromide in the treatment of asthma-chronic obstructive pulmonary disease overlap syndrome
XU Shuo
Objective To investigate the therapeutic effect of inhaled corticosteroid combined with Tiotropium Bromide in the treatment of patients with asthma-chronic obstructive pulmonary disease (COPD) overlap syndrome.Methods Sixty patients with asthma-COPD overlap syndrome who were admitted to our hospital from June 2017 to June 2018 were selected as the subjects.They were divided into the control group and the observation group by random number table method,with 30 cases in each group.In the control group,corticosteroid inhalation alone was used,while in the observation group,Tiotropium Bromide was added on the basis of corticosteroid inhalation.The pulmonary function,asthma control test (ACT) score,COPD assessment test (CAT) score,and the occurrence of complications after medication were compared between the two groups.Results There were no significant differences in the forced expiratory volume in one second (FEV1),residual volume/total lung capacity (RV/TLC),and inspiratory capacity/total lung capacity (IC/TLC),ACT score or CAT score between the two groups before the treatment (P>0.05).After treatment,the ratio of IC/TLC and FEV1 in the observation group were higher than those in the control group,and RV/TLC was lower compared with that in the control group,with statistical significance (P<0.05).The total incidence of palpitations,dry mouth,inhibited urination,and oral candida infection was lower than that of the control group after treatment (P<0.05).The ACT score of the observation group was higher than that of the control group,and CAT score was lower than that of the control group after treatment,and the differences were statistically significant (P<0.05).Conclusion The application of inhaled corticosteroid combined with Tiotropium Bromide in the treatment of patients with asthma-COPD overlap syndrome is better than inhaled corticosteroid therapy alone,and can reduce the incidence of complications and promote the recovery of lung function,and reduce the occurrence of asthma and COPD patients,which has high clinical value and is worthy of widespread promotion.
2019 Vol. 26 (27): 70-72 [Abstract] ( 195 ) HTML (32 KB)  PDF  (0 KB)  ( 16 )
73 Clinical effect of Total Glucosides of Paeony Capsules combined with Acitretin Capsules in the treatment of refractory psoriasis
CHEN Li;WEI Ming
Objective To explore the clinical effect of Total Glucosides of Paeony Capsules combined with Acitretin Capsules in the treatment of refractory psoriasis.Methods A total of 68 patients with refractory psoriasis treated in our hospital from January 2016 to December 2018 were selected and randomly divided into the control group and the observation group,34 cases in each group.Patients in the control group were given Acitretin Capsules,and patients in the observation group were given Total Glucosides of Paeony Capsules combined with Acitretin Capsules.The levels of Interleukin 4 (IL-4),Interleukin 8 (IL-8),and tumor necrosis factor-α (TNF-α),psoriasis area and severity index (PASI),and adverse reactions were compared between the two groups.Results After 8 weeks of treatment,the levels of IL-4,IL-8,and TNF-α in the observation group were significantly lower than those in the control group,the difference was statistically significant (P＜0.05).After 8 weeks of treatment,the PASI score in the observation group was significantly lower than that in the control group,the difference was statistically significant (P＜0.05).The total incidence of adverse reactions was 5.88% in the observation group and 17.65% in the control group,there was no significant difference between the two groups (P＞0.05).Conclusion Total Glucosides of Paeony Capsules combined with Acitretin Capsules in the treatment of refractory psoriasis can effectively relieve the inflammatory reactions,help to reduce the severity of skin lesions,and has a certain degree of safety.
2019 Vol. 26 (27): 73-75 [Abstract] ( 236 ) HTML (31 KB)  PDF  (0 KB)  ( 15 )
76 Influence of early continuous blood purification on prognosis of heat stroke
DING Dao-yin;HU Quan;HU Wang-ping;LI Xue
Objective To explore the influence of early blood purification on prognosis in patients with heat stroke.Methods The clinical data of 23 patients with heat stroke admitted to our department from June 2017 to September 2018 were analyzed retrospectively.The patients were divided into the observation group(12 cases)and the control group(11 cases) according to whether they were given continuous blood purification treatment in the early stage or not.The observation group was given continuous blood purification treatment in the early stage,while the control group was given routine treatment.The changes of blood pressure,respiration,heart rate,body temperature,creatinine(Cr),alanine aminotransferase (ALT),creatine phosphorylase-isoenzyme (CK-MB) and the final prognosis were compared between the two groups after 24 and 48 hours of treatment.Results The body temperature and heart rate of the two groups after 24 hours of treatment were lower than those before treatment,and the blood pressure and oxygenation index of the two groups after 24 hours of treatment were higher than those before treatment,the differences were statistically significant (P＜0.05).The body temperature and heart rate of the observation group were lower than those of the control group after 24 hours of treatment,and the blood pressure and oxygenation index of the two groups after 24 hours of treatment were higher than those of the control group,the differences were statistically significant (P＜0.05).There was no significant difference in body temperature,heart rate,blood pressure and oxygenation index between the two groups after 48 hours of treatment (P＞0.05).The biochemical indexes of CR,ALT and CK-MB in the observation group were lower than those in the control group after 24 and 48 hours of treatment,the differences were statistically significant (P＜0.05).There was no death in the observation group,and the mortality rate was 0.0%.There were 3 cases of deaths in the control group,and the mortality rate was 27.3%.There was significant difference between the two groups (P＜0.05).Conclusion Early continuous blood purification therapy can improve symptoms in patients with heat stroke,and reduce the mortality rate.
2019 Vol. 26 (27): 76-78 [Abstract] ( 275 ) HTML (37 KB)  PDF  (0 KB)  ( 13 )
79 Value of restrictive fluid management strategy in the prevention of early pulmonary complications during early stage after severe burn
LIN Feng-juan;YAO Song-zhen
Objective To evaluate the value of restrictive fluid management in the prevention of early pulmonary complications after severe burns.Methods A total of 60 cases of patients with severe burns admitted to the burn department of our hospital from January 2015 to January 2019 were selected as the subjects,and divided into control group and observation group,with 30 cases in each group,they were treated with conventional liquid management and restricted liquid management respectively.The extra vascular lung water index (EVLWI),pulmonary vascular permeability index (PVPI) and oxygenation index (PaO2/FiO2) at different time of burn recovery period and the incidence of complications were recorded and compared.Results At the end of shock,there was no significant difference in ELWI between the two groups （P>0.05）.After treatment,EVLWI of the observation group at each time point were significantly lower than those in the control group (P<0.05).There were no significant differences in PVPI between the two groups at the end of shock and at each time point after treatment (P>0.05).At the end of shock,there was no significant difference in PaO2/FiO2between the two groups (P>0.05).After treatment,PaO2/FiO2 of the observation group at each time point was significantly higher than that in the control group (P<0.05).During the treatment,the ventilator utilization rate,lung infection rate and acute respiratory distress syndrome (ARDS) rate in the observation group were significantly lower than those in the control group (P<0.05).Conclusion Restrictive fluid management in the early stage of severe burns can significantly improve EVLWI and PaO2/FiO2,reduce adverse reactions,and play an important role in the prevention of pulmonary complications.
2019 Vol. 26 (27): 79-81-85 [Abstract] ( 207 ) HTML (39 KB)  PDF  (0 KB)  ( 15 )
82 Influence of dynamic monitoring PCT on prognosis in patients with serious secondary peritonitis after surgery
JIANG Zi-xin;XIONG Xu-min;ZHANG Zhen-hui;WEN Yi-chao;LI Zhi-bo
Objective To investigate the influence of serum procalcitonin (PCT) levels and changes after treatment on the prognosis and survival of patients with severe secondary peritonitis.Methods The clinical data of 118 patients with severe secondary peritonitis after operation admitted to ICU of the Second Affiliated Hospital of Guangzhou Medical University from January 2016 to January 2018 were analyzed retrospectively.According to 28-day survival or not,they were divided into the survival group (95 cases) and the death group (23 cases).One week after treatment,108 surviving patients were divided into the PCT value decreased greater than or equal to 80% group (68 cases) and the PCT value decreased less than 80% group (40 cases).A total of 200 non-infected patients in the same period were selected as the normal control group.The PCT values of 1,3 and 7 days were observed dynamically,and the relationship between PCT values and severity and survival rate was summarized.Results The median of initial PCT values in the death group,the survival group and the normal control group were 9.10,7.91 and 0.04 ng/L,respectively,there was significant difference among the three groups (P＜0.05).The area under the ROC curve of 7-day PCT value was the largest.The cut-off point was 9.3 ng/L,the sensitivity was 0.933,and the specificity was 0.968.There was a positive correlation between the CT value on 3 and 7 day and the length of stay in ICU (P＜0.05).The change of APACHE Ⅱscore was positively correlated with CT value at 3 and 7 days (P＜0.05).The monthly survival rate of the PCT value decreased greater than or equal to 80% group after one week of treatment was significantly higher than that of the PCT value decreased less than 80% group (P＜0.05).Conclusion Dynamic monitoring of serum PCT can evaluate the prognosis of patients with severe secondary peritonitis after surgery.
2019 Vol. 26 (27): 82-85 [Abstract] ( 238 ) HTML (34 KB)  PDF  (0 KB)  ( 13 )
86 Value of neutrophil to lymphocyte ratio in predicting the prognosis of patients with sepsis
LUO Hui-jun;WU Shu-guo;DU Zhi-xiang;ZHANG Wei-xing
Objective To study the value of neutrophil to lymphocyte ratio in predicting the prognosis of sepsis patients.Methods The clinical data of 50 patients with sepsis treated in Chashan Hospital of Dongguan City from July 2017 to March 2019 were retrospectively analyzed.A total of 12 patients died of ineffective treatment at 28 days after the onset of sepsis were taken as the death group,and 38 patients who survived at 28 days after the onset of sepsis were taken as the survival group.The severity of sepsis and clinical indicators (including blood lactate test value,acute physiology and chronic health score system score value,neutrophil to lymphocyte ratio,procalcitonin test value,platelet count test value,white blood cell number test value) of the two groups were compared.Results The proportion of septic shock in the death group was higher than that in the survival group,and the proportion of sepsis in the death group was lower than that in the survival group,the difference was statistically significant (P＜0.05).The values of blood lactate,acute physiology and chronic health score system,neutrophil to lymphocyte ratio in the death group were higher than those in the survival group,and the differences were statistically significant (P＜0.05).There was no significant difference in procalcitonin,platelet count and white blood cell count between the two groups (P＞0.05).Conclusion The ratio of neutrophil to lymphocyte is of important value in predicting the prognosis of sepsis patients.
2019 Vol. 26 (27): 86-88 [Abstract] ( 222 ) HTML (32 KB)  PDF  (0 KB)  ( 21 )
89 Value of pulmonary alveolar lavage fluid Mycobacterium tuberculosis RNA combined with Xpert detection in the diagnosis of smear-negative pulmonary tuberculosis
ZHOU Zheng-hua;LIANG Zhi-yong;DENG Xiao-dong
Objective To investigate the clinical value of pulmonary alveolar lavage fluid Mycobacterium tuberculosis RNA combined with Xpert detection in the diagnosis of smear-negative pulmonary tuberculosis.Methods A total of 348 patients with smear-negative pulmonary tuberculosis treated in the Department of Respiratory Medicine of Chronic Disease Prevention Hospital of Qingyuan City from February 2017 to October 2018 were selected as research subjects.All patients were detected by pulmonary alveolar lavage fluid Mycobacterium tuberculosis RNA combined with Xpert.Taken the culture of pulmonary alveolar lavage fluid Mycobacterium tuberculosis as the gold standard for diagnosis,the sensitivity,specificity,accuracy,Youden index,positive likelihood ratio and negative likelihood ratio of the combined detection and single detection of smear-negative pulmonary tuberculosis were compared.Results The sensitivity,specificity,accuracy,Youden index,and positive likelihood ratio of the combined detection of pulmonary alveolar lavage fluid Mycobacterium tuberculosis RNA and Xpert were significantly higher than those of single detection,the negative likelihood ratio was lower than that of single detection,and the differences were statistically significant (P<0.05).Conclusion The pulmonary alveolar lavage fluid Mycobacterium tuberculosis RNA combined with Xpert detection has an important clinical value in the diagnosis of smear-negative pulmonary tuberculosis and it is worthy of wide application.
2019 Vol. 26 (27): 89-91-95 [Abstract] ( 170 ) HTML (34 KB)  PDF  (0 KB)  ( 14 )
92 Influence of mindfulness based cognitive therapy on social function and quality of Life in patients with depressive disorder
XIE Ji-qun;WANG Mei;TAN Feng-ling;HAO Jun-feng;LI Gui-lan
Objective To investigate the influence of mindfulness based cognitive therapy (MBCT) on quality of life and social function in patients with depressive disorder.Methods A total of 94 patients with depressive disorder admitted to psychiatry department of our hospital from June 2017 to June 2018 were selected as the research objects.According to the random number table method,they were randomly divided into the intervention group and the control group,47 cases in each group.The control group was given routine treatment,while the intervention group was given MBCT intervention on the basis of routine treatment.The Hamilton depression scale (HAMD-17),personal and social function scale(PSP-CHN) and World Health Organization quality of life scale-bref (WHOQOL-BREF) were used to evaluate blindly before and after the intervention for 8 weeks.Results The HAMD-17 score of the intervention group after 8 weeks of intervention was lower than that of the control group,and PSP-CHN was higher than that of the control group,with significant difference (P＜0.05).The scores and total scores of WHOQOL-BREF of the intervention group after 8 weeks of intervention were higher than those of the control group,with significant difference (P＜0.05).Conclusion MBCT can effectively improve depressive symptoms,social function and quality of life in patients with depression.
2019 Vol. 26 (27): 92-95 [Abstract] ( 249 ) HTML (33 KB)  PDF  (0 KB)  ( 14 )
96 Comparison of therapeutic effect between extensive lumpectomy and local lumpectomy for phyllodes tumor of breast
HUANG He-qing;ZHONG Mu-yi
Objective To explore the effect between extensive lumpectomy and local lumpectomy for phyllodes tumor of breast.Methods A total of 100 patients with phyllodes tumor of breast admitted to our hospital from January 2011 to May 2013 were selected as the research objects.According to different surgical methods,they were divided into observation group and control group,50 cases in each group.Patients in the observation group were treated with extensive lumpectomy,while patients in the control group were treated with local lumpectomy.The limb function (flexion,extension,internal rotation,abduction,external rotation,touch height) of the affected side 1 year after operation,disease recurrence rate and survival rate 5 years after operation were compared between the two groups.Results There were no significant difference in muscle strength,flexion,extension and pronation between the observation group and the control group (P>0.05).The abduction degree,abduction degree and touch height of the affected limb in the observation group were higher than those in the control group,and the differences were statistically significant (P<0.05).The disease recurrence rate in the observation group (12.0%) was compared with that in the control group (14.0%) at 5 years after operation,and the difference was not statistically significant (P>0.05).The 5-year survival rate of the observation group(12.0%) was not statistically significant compared with that of the control group (10.0%) (P>0.05).ConclusionIn the treatment of breast phyllodes tumor,extensive lumpectomy has a better prognosis than local lumpectomy,which is worthy of clinical application.
2019 Vol. 26 (27): 96-98 [Abstract] ( 175 ) HTML (32 KB)  PDF  (0 KB)  ( 16 )
99 Effect of high-frequency electrocoagulation and electric snare in the treatment of colorectal polyps under electronic colonoscope
QU Jian;PAN Xin-zhi;GUO Li-mei
Objective To investigate the effect of high-frequency electrocoagulation and electric snare under enteroscopy in the treatment of colorectal polyps.Methods A total of 172 patients with colorectal polyps admitted to our hospital from January 2017 to June 2018 were selected as research objects and divided into observation group and control group according to different treatment methods,86 cases in each group.Patients in the observation group were treated with high-frequency electrocoagulation and electric snare under electronic colonoscopy,while patients in the control group were treated with endoscopic biopsy forceps.The polypectomy,perioperative complications,operation time and hospitalization time of the two groups were compared.Results The total removal rate of polyps in the observation group (97.67%) and the overall resection rate (100.00%) were higher than those of the control group (82.56%,97.67%),the differences were statistically significant (P<0.05).The total incidence of complications in the observation group(18.60%) was lower than that in the control group (26.74%),and the difference was statistically significant (P<0.05).The operation time ([41.85±10.36]min) and hospitalization time ([5.32±1.63]d) in the observation group were shorter than those in the control group ([47.67±8.45]min,[7.25±1.24]d),the differences were statistically significant (P<0.05).Conclusion The treatment of colorectal polyps by high frequency electrocoagulation and electric snare under electronic colonoscopy has the characteristics of high safety factor and low incidence of complications.It can speed up wound healing time of patients,shorten hospitalization time,reduce patients′ body and life burden,and has high clinical application value.
2019 Vol. 26 (27): 99-101 [Abstract] ( 215 ) HTML (32 KB)  PDF  (0 KB)  ( 13 )
102 Application effect of Metoprolol in the treatment of patients with septic shock
CHEN Da-yang;GAO Yong-you;CEN Zhong-ran;GUAN Yuan-zhi
Objective To investigate the effect of Metoprolol in the treatment of patients with septic shock.Methods From July 1,2017 to March 31,2019,40 patients with septic shock admitted to Yangjiang Traditional Chinese Medicine Hospital,Zhujiang Hospital in Guangzhou City and Yangchun People′s Hospital were selected as research objects,the patients were divided into conventional treatment group and Metoprolol group by random number table method,with 20 cases in each group.Patients in the conventional treatment group received routine treatment,while patients in the Metoprolol group received Metoprolol treatment on the basis of routine treatment.The heart rate,mean arterial pressure,central venous pressure (CVP),central venous oxygen saturation (ScvO2) and urine volume before and after treatment were compared between the two groups.The cardiac index (CI) and peripheral vascular resistance index(SVRI) of the two groups were compared at different time after treatment (4,8,16,24,36,48,72,96 h after treatment).The incidence of heart failure and death in 28 d were compared between the two groups.Results Before treatment,there were no significant difference in heart rate,mean arterial pressure,CVP,ScvO2,urine volume,CI and SVRI between the two groups (P>0.05).There was no significant difference in the mean arterial pressure between the two groups before and after treatment (P>0.05).The heart rate of Metoprolol group after treatment was slower than that before treatment,the difference was statistically significant (P<0.05).There was no significant difference in heart rate before and after treatment in conventional treatment group (P>0.05).After treatment,the CVP,ScvO2 and urine volume of the two groups of patients were higher than before treatment,the differences were statistically significant (P<0.05).After treatment,the heart rate of Metoprolol group was slower than that of the conventional treatment group,and the CVP,ScvO2 and urine volume were higher than those of the conventional treatment group,the differences were statistically significant (P<0.05).There was no significant difference in the mean arterial pressure between the two groups (P>0.05).There were no significant difference between the two groups in CI (4,8,16,24,36,48,72,96 h after treatment) and SVRI (8,16,24,36,48,72,96 h after treatment) (P>0.05).SVRI of Metoprolol group was lower than that of conventional treatment group 4 h after treatment,the difference was statistically significant (P<0.05).The incidence of heart failure(40.0%) and 28 d mortality (10.0%) in Metoprolol group were lower than those in conventional treatment group (75.0%and 40.0%),the differences were statistically significant (P<0.05).Conclusion The application of Metoprolol to sepsis on the basis of full fluid resuscitation and stable hemodynamics can effectively reduce heart rate,heart failure rate and 28 d mortality,which is worthy of promotion.
2019 Vol. 26 (27): 102-105 [Abstract] ( 190 ) HTML (39 KB)  PDF  (0 KB)  ( 17 )
106 Clinical effect of Bifid triple viable bacteria combined with Montmorillonite Powder in the treatment of acute enteritis
HU Jun;HUANG Xiao-mei
Objective To explore the clinical effect of Bifid triple viable bacteria combined with Montmorillonite Powder in the treatment of acute enteritis.MethodsEighty-eight patients with acute enteritis admitted to our hospital from February 2016 to February 2018 were selected as the study subjects,they were divided into observation group (30 cases) and control group (30 cases) according to random number table method.The observation group was treated with Bifid triple viable bacteria combined with Montmorillonite Powder,while the control group was treated with Montmorillonite Powder.The serum biochemical indexes,total effective rate and symptom score before and after treatment were compared between the two groups.Results After treatment,the levels of Procalcitonin (PCT),interleukin-8 (IL-8) and interleukin-6 (IL-6) in the observation group were lower than those in the control group,the differences were statistically significant (P<0.05).The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant (P<0.05).The scores of diarrhea,vomiting,abdominal pain and total symptoms in the observation group were lower than those in the control group,the differences were statistically significant (P<0.05).Conclusion Bifid triple viable bacteria combined with Montmorillonite Powder in the treatment of acute enteritis clinical effect is significant,can effectively reduce the level of inflammatory factors in patients,improve the treatment effect of patients,improve the symptoms of patients,which is worthy of clinical application.
2019 Vol. 26 (27): 106-108-112 [Abstract] ( 206 ) HTML (33 KB)  PDF  (0 KB)  ( 20 )
109 Effect of Salmeterol Fluticasone Propionate in the treatment of bronchial asthma
SONG Qing-jun;DU Lin;SHEN Ting-dong;XIAO Tao
Objective To explore the effect of Salmeterol Fluticasone Propionate in the treatment of bronchial asthma.Methods A total of 103 patients with bronchial asthma admitted to our hospital from March 2017 to November 2018 were selected as the study objects,and they were divided into control group (51 cases) and observation group (52 cases)according to the random number table method.The control group was treated with Salmeterol Hydroxynaphthoate Powder for Inhalation combined with Fluticasone Propionate Inhaled Aerosol,and the observation group was treated with Salmeterol Fluticasone Propionate.The therapeutic effect,pulmonary function (forced expiratory volume in the first second [FEV1),ratio of FEV1 occupational forced vital capacity [FVC][FEV1/FVC],peak expiratory flow [PEF]) and maximum peak expiratory flow rate in the morning (PEFam) before and after treatment were compared in the two groups.Results There were no significant differences in FEV1,FEV1/FVC and PEF between the two groups before treatment(P>0.05).The FEV1,FEV1/FVC and PEF of the two groups after treatment were higher than those before treatment,and the differences were statistically significant (P<0.05).The FEV1,FEV1/FVC and PEF of the observation group after treatment were higher than those of the control group,and the differences were statistically significant (P<0.05).There was no significant difference in PEFam between the two groups before treatment (P>0.05).The PEFam at the first,second,third,and fourth weeks after treatment in both groups were significantly higher than those before treatment,and the differences were statistically significant (P<0.05).The PEFam at the first,second,third,and fourth weeks after treatment in the observation group were significantly higher than those in the control group,and the differences were statistically significant (P<0.05).The total effective rate of the treatment in the observation group was 94.23%,which was significantly higher than that in the control group (84.31%),and the difference was statistically significant (P<0.05).Conclusion The use of Salmeterol Fluticasone Propionate in the treatment of bronchial asthma can effectively improve the pulmonary function of patients,increase the flow rate of the exhalation,relieve clinical symptoms,and the treatment effect is more obvious.
2019 Vol. 26 (27): 109-112 [Abstract] ( 180 ) HTML (38 KB)  PDF  (0 KB)  ( 14 )
113 Application effect ultrasound-guided transabdominal transverse muscle plane nerve block combined with intravenous analgesia pump in the treatment of cholangiocarcinoma after radical operation
LIU Miao
Objective To explore the application effect of ultrasound-guided transabdominal transverse muscle plane nerve block combined with intravenous analgesia pump in the treatment of cholangiocarcinoma after radical operation.Methods Seventy-four patients with cholangiocarcinoma radical operation admitted to our hospital from August 2017 to December 2018 were enrolled in the study,they were divided into control group (n=37) and study group (n=37) according to the random number table method.The control group was treated with intravenous analgesia pump analgesia.The study group underwent ultrasound-guided transabdominal transverse muscle plane nerve block combined with intravenous analgesia pump analgesia.The pain visual analog scale (VAS) scores before and after surgery,the incidence of postoperative analgesic drug adverse reactions,postoperative recovery and psychological status before and after surgery were compared.Results The VAS scores of the study group at 2,6,12,and 24 h after operation were lower than those of the control group,the differences were statistically significant (P<0.05).The total incidence of postoperative analgesic drug adverse reactions in the study group was lower than that in the control group,the difference was statistically significant (P<0.05).The time of getting out of bed,exhaust time and recovery time were shorter in the study group than those of the control group,the differences were statistically significant (P<0.05).The positive emotion scores of the study group at 24 h after operation were higher than those of the control group,and the negative emotion scores were lower than those of the control group,and the differences were statistically significant (P<0.05).Conclusion Ultrasound-guided transabdominal transverse muscle plane nerve block combined with intravenous analgesia pump can improve the pain level of patients after cholangiocarcinoma radical resection,reduce the occurrence of analgesic drug adverse reactions,and regulate the psychological state of patients.
2019 Vol. 26 (27): 113-116 [Abstract] ( 1712 ) HTML (37 KB)  PDF  (0 KB)  ( 14 )
118 Application value of ultrasound-guided transversal abdominis plane block in combined spinal-epidural anesthesia of cesarean section
WEN Ri-xin;WANG Xing-gao;LIAO Rong-zhen;ZHUO Rui;CHEN Guang-tian
Objective To explore the application value of ultrasound-guided transversal abdominis plane (TAP) block in combined spinal-epidural anesthesia of cesarean section.Methods Sixty puerpera who underwent cesarean section with combined spinal and epidural anesthesia from March 2017 to March 2018 admitted to our hospital were divided into experimental group and control group according to the random number table method,with 30 cases in each group.The control group was given combined spinal-epidural anesthesia + traditional TAP block anesthesia,while the experimental group was given combined spinal-epidural anesthesia + ultrasound-guided TAP block.The heart rate,mean arterial pressure and pain score (visual analogue scale [VAS]score) before the incision,at the time of delivery and at the end of the operation of the two groups were compared.The pain scores at 2,4,8,16,24,and 36 h after surgery of the two groups were compared.The occurrence of intraoperative traction reaction,adverse reactions (nausea and vomiting)of the two groups were compared.The number of times that the analgesic pump was pressed,and the time required for the first time to go to the ground of the two groups were compared.Results The heart rate,mean arterial pressure and VAS scores of the experimental group were lower than those of the control group before skin incision,at the time of fetal delivery and at the end of the operation,and the differences were statistically significant (P<0.05).There was no significant difference in VAS score between the two groups 2 h after operation (P>0.05).The VAS scores of the experimental group at 4,8,16,24,36 h after delivery were lower than those of the control group,the differences were statistically significant (P<0.05).The incidence of traction reaction and adverse reactions during operation in the experimental group were lower than those in the control group,the number of times that the analgesic pump was pressed was fewer than that in the control group,and the time required for the first time to go to the ground was shorter than that in the control group,the differences were statistically significant (P<0.05).ConclusionUltrasound-guided TAP block is more effective in cesarean section combined with spinal and epidural anesthesia.It can effectively reduce the incidence of adverse reactions and relieve postoperative pain,thus it is worthy of promotion and application.
2019 Vol. 26 (27): 118-120 [Abstract] ( 163 ) HTML (36 KB)  PDF  (0 KB)  ( 11 )
121 Application value of color Doppler ultrasonography in detecting uterine artery blood flow spectrum in middle and late pregnancy-induced hypertension syndrome
LIANG Zhen;ZHOU Ting;YIN Chun-hui
Objective To explore the application value of color Doppler ultrasonography in detecting uterine artery blood flow spectrum in middle and late pregnancy-induced hypertension syndrome.Methods Sixty cases of pregnant women in the middle and late pregnancy were selected as the research objects from October 2018 to January 2019,All pregnant women were examined by color Doppler ultrasound,they were divided into control group and observation group according to whether there was pregnancy-induced hypertension syndrome (PIH),30 cases in each group.The control group was healthy pregnant women in the second and third trimesters of pregnancy,while the observation group was pregnant women with hypertension syndrome in the second and third trimesters of pregnancy,the observation group included 8 cases of gestational hypertension,12 cases of preeclampsia and 10 cases of preeclampsia.The arterial pulsation index (PI),resistance index (RI),the ratio of systolic and diastolic blood pressure of fetal umbilical artery (S/D) and the positive rates of PI,RI and S/D were compared between the two groups.Results The PI,RI and S/D of pregnant women in the observation group were higher than those in the control group,the differences were statistically significant(P<0.05).The PI,RI and S/D values of preeclampsia pregnant women were higher than those of preeclampsia and pregnancy-induced hypertension pregnant women,and the PI,RI and S/D values of preeclampsia pregnant women were higher than those of pregnancy-induced hypertension pregnant women,the differences were statistically significant (P<0.05).The positive rates of PI,RI and S/D of pregnant women in the observation group were 93.33%,90.00% and 86.67% respectively,which were higher than those in the control group 6.67%,10.00% and 6.67%,respectively,the differences were statistically significant (P<0.05).Conclusion Prenatal examination in middle and late pregnancy can provide reliable side reference for physicians to differentiate pregnancy-induced hypertension syndrome according to the color Doppler ultrasound of uterine artery blood flow of pregnant women,it has good application value.
2019 Vol. 26 (27): 121-123 [Abstract] ( 185 ) HTML (33 KB)  PDF  (0 KB)  ( 18 )
124 Ultrasound features of gallbladder examination in patients with cirrhosis and ascites
XIONG Mei-e;LIU Rong;CHEN Qing
Objective To explore the value of ultrasonography in gallbladder examination in patients with cirrhosis and ascites.Methods A total of 30 patients with ascites due to cirrhosis (study group) and 30 healthy persons (control group) received in our hospital from June 2015 to October 2018 were selected as objects.They were underwent ultrasound gallbladder examination.The gallbladder thickness,gallbladder volume and postprandial gallbladder excretion were compared between the two groups.Results The thickness of gallbladder in the study group was larger than that in the control group,and the volume of gallbladder in fasting and postprandial periods were smaller than those in the control group,and the amount of gallbladder excretion in different postprandial periods were less than those in the control group,the differences were statistically significant (P<0.05).Conclusion The results of gallbladder ultrasonography in patients with cirrhosis and ascites are different from those in normal people,which can provide reference for clinical diagnosis.
2019 Vol. 26 (27): 124-126 [Abstract] ( 179 ) HTML (31 KB)  PDF  (0 KB)  ( 16 )
127 Application value of vaginal ultrasound and abdominal ultrasound in gynecological diseases
CHEN Jun-ying;WU Xiao-lu;LIU Chan
Objective To explore the application value of vaginal ultrasound and abdominal ultrasound diagnosis in obstetrics and gynecology diseases.Methods A total of 126 patients suspected with gynecologic diseases admitted to our hospital from May 16,2017 to May 16,2018 were selected as the research objects.Each patient was examined by vaginal ultrasound and abdominal ultrasound.Taking pathological biopsy results as gold standard,the diagnostic accuracy,specificity,sensitivity,misdiagnosis rate and missed diagnosis rate of the two ultrasound examination methods were compared.Results The diagnostic accuracy of vaginal ultrasound for placenta previa,acute pelvic inflammatory disease,ectopic pregnancy,corpus luteum rupture,adenomyosis (100.00%,93.75%,94.74%,100.00%,98.25%) were higher than those of abdominal ultrasound (60.00%,62.50%,63.16%,83.33%,71.93%),the differences were statistically significant (P<0.05).The sensitivity and specificity of vaginal ultrasound in the diagnosis of obstetrics and gynecology diseases (97.09%,95.65%) were higher than those of abdominal ultrasound (68.93%,69.57%),the differences were statistically significant (P<0.05).The misdiagnosis rate and the missed diagnosis rate of vaginal ultrasound in the diagnosis of obstetrics and gynecology diseases (4.35%,2.91%) were lower than those of abdominal ultrasound (30.43%,31.07%),the differences were statistically significant (P<0.05).Conclusion Vaginal ultrasound examination can provide more reliable basis for the diagnosis of diseases and the formulation of diagnosis and treatment plans,can improve the correct diagnosis rate of diseases and reduce the misdiagnosis rate and missed diagnosis rate.
2019 Vol. 26 (27): 127-129-133 [Abstract] ( 171 ) HTML (33 KB)  PDF  (0 KB)  ( 15 )
130 Clinical effect of Paroxetine combined with Olanzapine in the treatment of long-term hospitalized schizophrenia patients with anxiety symptoms
XIE Sui-feng;LI Lun;YE Fen
Objective To investigate the clinical effect of Paroxetine combined with Olanzapine in the treatment of long-term hospitalized schizophrenia patients with anxiety symptoms.Methods A total of 80 long-term hospitalized schizophrenia patients with anxiety symptoms treated in our hospital from July 2017 to December 2018 were selected as the subjects,they were divided into two groups according to the random number table method,with 40 cases in each group.The control group was treated with Olanzapine tablets,while the study group was treated with Paroxetine on basis of the control group.The clinical efficacy,anxiety,severity of illness and occurrence of adverse reactions were compared between the two groups.Results The total effective rate of the study group was 95.00%,which was higher than that of the control group (80.00%),with statistical significance (P<0.05).The self-rating anxiety scale (SAS) score of the study group was (31.65±7.98) point,which was lower than that of the control group ([45.78±9.23]point),with statistical significance (P<0.05).The negative symptoms,positive symptoms,general psychiatry and total scores of the study group were lower than those of the control group,the differences were statistically significant (P<0.05).There was no serious adverse reactions occurred in both groups during the treatment.Conclusion Paroxetine combined with Olanzapine can effectively alleviate anxiety symptoms and severity of anxiety symptoms in long-term hospitalized schizophrenia patients with anxiety symptoms,without increasing toxicity and side effects,and with high safety.
2019 Vol. 26 (27): 130-133 [Abstract] ( 186 ) HTML (33 KB)  PDF  (0 KB)  ( 13 )
134 Clinical effect of Argatroban combined with Clopidogrel in the treatment of acute posterior circulation cerebral infarction
GUO Li-sha;SUN Qiang;XING Hui-juan;LIU Xiao-lin;FANG Xiao
Objective To analyze the clinical effect of Argatroban combined with Clopidogrel in the treatment of acute posterior cerebral infarction.Methods Sixty-seven patients with acute posterior circulation cerebral infarction admitted to our hospital from January 2017 to February 2018 were selected as the subjects.They were divided into control group(35 cases) and observation group (32 cases) by random number selection method.The control group received Aspirin plus Clopidogrel.The observation group received Argatroban plus Clopidogrel.The clinical efficacy,total adverse reaction incidence,neurological deficit (NIHSS) score and quality of life (BI) score were compared between the two groups.Results The total effective rate of the disease in the observation group was higher than that in the control group,and the difference was statistically significant (P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups (P>0.05).The NIHSS score of the observation group was lower than that of the control group,and the difference was statistically significant (P<0.05).The BI score of the observation group was higher than that of the control group,and the difference was statistically significant (P<0.05).Conclusion Patients with acute posterior circulation cerebral infarction receiving Argatroban combined with Clopidogrel can significantly improve the patients′ condition and has fewer adverse reactions,which is worthy of being promoted and applied.
2019 Vol. 26 (27): 134-136 [Abstract] ( 204 ) HTML (34 KB)  PDF  (0 KB)  ( 19 )
137 Clinical effect of acupuncture combined with manipulation in treatment of vertebral artery type cervical spondylosis
LIAN Zhen-biao;LIANG Qi;YOU Rong-hua;LI Zi-yan
Objective To explore the clinical effect of acupuncture combined with manipulation in treatment of vertebral artery type cervical spondylosis.Methods All of 100 patients with vertebral artery type cervical spondylosis admitted to our hospital from January 5,2016 to January 5,2019 were selected as study subjects.They were divided into the observation group (50 cases) and control group (50 cases) according to the random number table method.The observation group was treated with acupuncture combined with manipulation,while the control group was treated with acupuncture.The mean blood flow velocity,pulsation index,peak systolic blood flow,resistance index,TCM syndrome score,clinical assessment scale for cervical spondylosis(CASCS)score and total effective rate were compared between the two groups.Results The mean blood flow velocity was (27.85±2.16) cm/s,peak systolic blood flow was (63.44±3.68) cm/s,CASCS score was (68.98±3.25) points,and the total effective rate was 96.00% in the observation group,which were higher than those in the control group ([20.29±2.54]cm/s,[51.58±2.19]cm/s,[51.17±2.33]points,72.00%),pulsation index was 0.52±0.13,resistance index was 0.33±0.08,TCM syndrome score was (1.16±0.22) points in the observation group,which were lower than those in the control group ([1.61±0.26],[0.86±0.22],[2.76±0.43]points) (P＜0.05).Conclusion The effect of acupuncture combined with manipulation in treatment of vertebral artery type cervical spondylosis is remarkable.
2019 Vol. 26 (27): 137-139 [Abstract] ( 195 ) HTML (33 KB)  PDF  (0 KB)  ( 18 )
140 Clinical effect of ear acupoint seed embedding in the treatment of perioperative insomnia in department of orthopaedics
FENG Mei-ying
Objective To investigate the clinical effect of ear acupoint seed embedding in the treatment of perioperative insomnia in department of orthopaedics.MethodsSixty patients with perioperative insomnia admitted to our hospital from January to March 2019 were selected as study objects and they were divided into the control group (30 cases) and observation group (30 cases) according to the random number table method.The control group was treated with conventional guidance and acupoint massage.The observation group was given ear acupoint seed embedding on the basis of the control group.The clinical efficacy,sleep quality and emotional state between the two groups were compared.Results The total effective rate of treatment in the observation group was significantly higher than that of the control group(P<0.05).Before treatment,there was no significant difference in the total Pitts burgh sleep quality idex (PSQI) score between the two groups (P>0.05),after treatment,the total PSQI score of the two groups were lower than those before treatment,and the observation group was significantly lower than that of the control group (P<0.01).After treatment,the SAS and SDS scores of both groups decreased,and the observation group was lower than the control group (P<0.01).Conclusion Ear acupoint seed embedding of traditional Chinese medicine can play an active role in improving sleep quality of patients with perioperative insomnia and alleviating patients′ bad mood.The effect is ideal and can be popularized and applied.
2019 Vol. 26 (27): 140-142 [Abstract] ( 179 ) HTML (31 KB)  PDF  (0 KB)  ( 16 )
143 Early diagnostic value of neutrophil gelatinase-associated lipid-carrying proteins in cardiorenal syndrome
SONG Xing-liang;CHENG Yan-mei;HUANG Jun;SHAO Xiang;XU Jing-lan;YAN Fei-ben
Objective To investigate the early diagnostic value of neutrophil gelatinase-associated lipid-carrying proteins (NGAL) in cardiorenal syndrome (CRS).MethodsA total of 165 patients with heart failure (HF) who were admitted to Shangrao People′s Hospital from November 2017 to October 2018 were seleted as the research objects.According to the CRS diagnostic guidelines,38 patients with acute decompensated heart failure (ADHF) and new acute kidney injury (AKI) were selected as the CRS group,and the remaining 127 patients were assigned as the control group.The urine NGAL (uNGAL),N-terminal pro-brain natriuretic peptide (N-proBNP),cystatin (Cys-C),urea nitrogen (BUN),and creatinine (SCr) levels were compared between the two groups.The levels of uNGAL,SCr,Cys-C and BUN at 0(baseline),2,4,8,18,48 h of CRS group were detected respectively.The value of uNGAL in the diagnosis of CRS was analyzed by receiver operating characteristic (ROC) curve.Results The levels of SCr,BUN,uNGAL,Cys-C and NTproBNP in the CRS group were higher than those in the control group,and the differences were statistically significant(P<0.05).The SCr and BUN levels in the CRS group at 48 h were significantly higher than those at the baseline,and the differences were statistically significant (P<0.05).The levels of uNGAL in the CRS group at 2,4,8,18,and 48 h were significantly higher than those at the baseline,the differences were statistically significant (P<0.05),and peaked at 2 and 4 h.The Cys-C levels at 4,8,18,and 48 h in the CRS group were higher than those at the baseline,and the differences were statistically significant (P<0.05).The ROC curve analysis showed that the AUC of the diagnosis of AKI at 2,4,8,and 18 h were 0.879,0.862,0.848,and 0.813,95% CI was 0.768-0.981,0.735-0.977,0.723-0.971,and 0.741-0.954,respectively.When 169.1 ng/ml was used as the cut-off value for the diagnosis of AKI,the sensitivity and specificity were 95.61% and 87.52%,respectively.Conclusion The uNGAL is associated with AKI in patients with ADHF during hospitalization,and it is an early independent predictor of renal function deterioration during hospitalization of HF patients,which is of great significance in the early diagnosis and early intervention of CRS patients.
2019 Vol. 26 (27): 143-146 [Abstract] ( 207 ) HTML (39 KB)  PDF  (0 KB)  ( 10 )
147 Analysis of influencing factors of prognosis of coronary heart disease
RUAN Xiao-yun;HU Wei-bo;AO Xi-hong
Objective To investigate the relationship between prothrombin fragment 1+2,D-dimer,Gensini score and prognosis of coronary heart disease(CHD).Methods A total of 114 patients with CHD admitted to our hospital from January 2017 to February 2018 were enrolled.According to the different prognosis of CHD,they were divided into the major adverse cardiovascular events (MACE) group (n=34) and the non-MACE group (n=80).The influencing factors of prognosis of CHD were analyzed.The risk factors of MACE were analyzed using COX model.Results The D-dimer and prothrombin fragment 1+2 in the non-MACE group were lower than those in the MACE group,the Gensini score in the non-MACE group was higher than that in the MACE group,with statistical significance (P＜0.05).There was no significant difference in male ratio,hypertension ratio,or left ventricular ejection fraction between the two groups (P＞0.05).A COX regression model was established.The occurrence of MACE was set as a dependent variable.The corrected multivariate COX regression analysis indicated D-dimer,prothrombin fragment 1+2,and Gensini score were independent predictors of MACE events,with statistical significance (P＜0.05).Conclusion Prothrombin fragment 1+2,D-dimer and Gensini score are independent predictors of CHD.Strengthening monitoring can provide a reliable theoretical basis in the guidance of clinical treatment.
2019 Vol. 26 (27): 147-149 [Abstract] ( 197 ) HTML (30 KB)  PDF  (0 KB)  ( 16 )
150 Application of thinprep cytologic test combined with HPV-DNA detection in diagnosis of cervical lesions
ZHUANG Jian;SHI Feng-quan;LI Wen-zhong;YUAN Yuan-ying;FENG Xu-fen;LI Li-li
Objective To investigate the application effect of thinprep cytologic test (TCT) combined with HPV-DNA detection in the diagnosis of cervical lesions.MethodsSixty-six patients with suspected cervical lesions enrolled in the Department of Obstetrics and Gynecology of our hospital from June 2017 to May 2018 were selected as the subjects.The TCT test and HPV-DNA test were performed respectively.The results of cervical biopsy were used as the gold standard.The sensitivity,specificity,and accuracy of TCT alone,HPV-DNA alone,and joint detections in cervical lesions were analyzed.Results The accuracy,sensitivity and specificity of detections in combination were 95.45%,95.83%,and 94.44%,higher than those of TCT alone accuracy,sensitivity and specificity (63.64%,68.75%,and 50.00%)and HPV-DNA alone (68.18%,72.92%,and 55.56%) in turn,with significant differences (P<0.05).There was no significant difference in sensitivity,specificity or sensitivity of TCT alone and HPV-DNA alone (P>0.05).Conclusion In the diagnosis of patients with early cervical lesions,the combined use of TCT and HPV-DNA tests is beneficial to the early diagnosis of its nature.The diagnostic accuracy is high,and can provide a reliable reference for clinical treatment.It is worth further in clinical practice.
2019 Vol. 26 (27): 150-152 [Abstract] ( 191 ) HTML (29 KB)  PDF  (0 KB)  ( 18 )
153 Influence of improved cleaning procedures on the cleaning quality of high-risk oral instruments
ZHANG Kai-li;ZHANG Zhi-qin;GUO Wen-juan
Objective To analyze the influence of improved cleaning procedures on the quality of high-risk oral instruments.Methods A total of 150 high-risk oral instruments used in the Department of Stomatology in our hospital from December 2017 to December 2018 were selected as the study samples.They were randomly divided into the observation group (n=75) and the control group (n=75) according to the random number table method.In the control group,conventional instrument cleaning procedure was used,while in the observation group,improved cleaning procedure was adopted.The cleaning effect and functional quality of oral instruments of the two groups were compared.Results The qualified rates of the protein residue assay,the 5x magnifying glass assay and the ATP fluorescence assay were 98.67%,97.33%,96.00%,which were higher than those of the control group accounting for 82.67%,80.00%,and 77.33%,with statistical significance (P＜0.05).The qualified rate of functional quality of oral instruments after cleaning in the observation group was 100.00%,which was better than that of the control group accounting for 86.67%,with significant difference (P＜0.05).Conclusion Improved cleaning procedure can effectively improve the cleaning effect and functional quality of high-risk oral instruments,and reduce the loss of equipment quality,which is worth promoting.
2019 Vol. 26 (27): 153-155 [Abstract] ( 156 ) HTML (31 KB)  PDF  (0 KB)  ( 14 )
156
Analysis of AIDS epidemic trend and characteristics in Xinjian District of Nanchang City from 2014 to 2018
Analysis of AIDS epidemic trend and characteristics in Xinjian District of Nanchang City from 2014 to 2018[J]. 中国当代医药, 2019,26(27): 156-158')" href="#"> WANG Fen
Objective To investigate the epidemic trend of AIDS in Xinjian District of Nanchang City,in order to take corresponding epidemic prevention and control measures,achieve the effect of AIDS transmission and spread prevention and control.Methods AIDS epidemic data in the Center for Disease Control and Prevention of Xinjian District of Nanchang City,Jiangxi Province from 2014 to 2018 were analyzed.Results The epidemic situation of AIDS in Xinjian District of Nanchang City showed an upward trend year by year.The ratio of male to female was 3.76∶1.The elderly over 60 years old and peasants were the main groups of AIDS infection;homosexual transmission and heterosexual transmission were the main transmission routes of AIDS.Conclusion The trend of AIDS epidemic in Xinjian District of Nanchang City is rising.It is an urgent task to pay attention to the life of the elderly,guide the sexual life of the public correctly,strengthen the prevention and control of AIDS in the county and district centers for disease prevention and control.
2019 Vol. 26 (27): 156-158 [Abstract] ( 216 ) HTML (27 KB)  PDF  (0 KB)  ( 17 )
159 Reforming teaching concepts and cultivating innovative medical undergraduates
CHEN Jia-long;MA Lu-mei
As the core strategy of national development,the key to the implementation of innovation-driven is the cultivation of innovative talents.Undergraduate education in the cultivation of talents in a core position,but the traditional teachers monologue type infusion textbook knowledge,is not suitable for innovative talent training requirements,teachers need to by the classroom “elites” transformation “leader”,in order to inspire,discussion and dialogue teaching presents the ways to cultivate students′ innovative thinking,rich teaching content to new progress in scientific research,fully combines scientific and effective teaching,the cultivation of the integrative innovation quality of medical undergraduate,solid foundation for medical career.
2019 Vol. 26 (27): 159-161 [Abstract] ( 181 ) HTML (31 KB)  PDF  (0 KB)  ( 13 )
162 Difficulties and countermeasures of community health service stations in Lingui District,Guilin City under the background of hierarchical diagnosis and treatment
YIN Jing-yi; WANG Yong-heng;WENG Yu-wen;LIU Meng-ting;ZENG Chun-ying;LI Xiao-yue
Community health service plays an important role in hierarchical medical system.Guilin City Lingui District.What we now face is the contradiction between inadequate capability of community health service and the people′s ever-growing needs for a better life.Insufficient funds in health services,the emerging of temporal migrationis,increasing proportion of elders are the plight of Lingui distric in Guilin city.Depending on community health service and“Internet+”,Lingui district improve capability of community health service under the background of hierarchical medical system.The aim is to satisfy the people′s ever-growing needs for health management of full life cycle.
2019 Vol. 26 (27): 162-164 [Abstract] ( 215 ) HTML (31 KB)  PDF  (0 KB)  ( 16 )
165 Positioning and optimization suggestions for the pharmaceutical department in the line and staff organization
YANG Ben
The pharmaceutical department has always been an important part of the medical institution.The pharmacy department,which is one of the departments of medical technology,also undertakes certain management functions.This paper discusses the positioning of pharmaceutical department in medical institutions based on organizational theory,and analyzes from the perspective of organization design.Then some suggestions are proposed for the pharmaceutical department to better perform its functions in medical institutions with the line and staff organization structure.Pharmacy department should be based on the position of technical department,its core functions should be highlighted,and its due role should be brought into full play;at the same time,specialized functional departments should be sut up to conduct administrative affairs such as drug administration of medical institutions.
2019 Vol. 26 (27): 165-167 [Abstract] ( 192 ) HTML (32 KB)  PDF  (0 KB)  ( 17 )
168 Application effect of PBL teaching method combined with demonstration teaching mode in nursing practice teaching
LIU Jia;ZHANG Bing;LIU Jin-miao;JIN Xin;SUN Yuan-bo;QI Yan
Objective To explore the application effect of PBL teaching method combined with demonstration method in nursing practice teaching.Methods From July to December 2018,76 nursing undergraduates were selected as teaching objects in Hongqi Hospital Affiliated to Mudanjiang Medical College.The students were divided into the the control group and observation group according to the random number table method,38 cases in each group.The control group was taught by conventional teaching methods,while the observation group was taught by PBL teaching method combined with demonstration teaching mode.After the completion of teaching,the teaching effect was evaluated from two aspects： learning effect and satisfaction survey of teaching mode.Results The scores of learning effect and the total satisfaction of teaching in the observation group were higher than those in the control group,and the differences were statistically significant (P＜0.05).Conclusion PBL teaching method combined with demonstration teaching method can effectively improve the teaching effect of nursing interns.
2019 Vol. 26 (27): 168-170-174 [Abstract] ( 155 ) HTML (35 KB)  PDF  (0 KB)  ( 19 )
171 Study on selection and construction of evaluation indicators for scientific research innovation ability of undergraduates in undergraduate education stage
HAN Wen-xia;SUN Jing;GENG Xiao-xiao;LI Wei-ze;HUO Jian;MAI Tian-hui;WEI Hui
The cultivation of university students′scientific and technological innovation ability has become the focus of talent cultivation in the new period of higher education development.Based on the characteristics and training orientation of medical technology college students,this paper studies and constructs an evaluation index system for screening scientific research and innovation ability of undergraduate students in undergraduate education stage.On the one hand,the construction of the evaluation index system takes students as the main body to study the internal conditions,on the other hand,we should take educators as the object to study the external factors and cultivate the scientific research and innovation ability of university students.At the same time,it studies the concrete practice method of the evaluation index system of University Students′ scientific research innovation ability under the combined effect of internal and external conditions.The purpose of this paper is to provide useful reference and reference for the evaluation of scientific research and innovation in colleges and schools,and to provide reference for the construction of scientific and technological innovation environment in colleges and universities.
2019 Vol. 26 (27): 171-174 [Abstract] ( 175 ) HTML (35 KB)  PDF  (0 KB)  ( 17 )
175 Application effect of flipping class combined with case teaching method in clinical pediatrics teaching
ZHOU Yan-ming
Objective To study the effect of flipping class combined with case teaching in clinical paediatrics teaching.Methods All of 80 rural medical students from Lianzhou Health School of Guangdong Province from September 2017 to January 2018 were selected as study objects and they were divided into the control group (40 cases) and observation group (40 cases) according to the class.The control group was given the traditional teaching method,while the observation group was given flipping class combined with case teaching method.The results of the test and questionnaire were compared between the two groups.Results The theoretical knowledge,skill operation,nursing etiquette,propaganda ability,communication ability and total score of the students in the observation group were higher than those in the control group (P<0.05).The proportion of students in the observation group who like this teaching mode was higher than that in the control group,and the proportion of students believing that this teaching mode could stimulate learning interest,enhance skill proficiency,improve the ability to analyze and solve problems,facilitate the integration and application of theoretical knowledge and practical skills,and enhance the awareness of teamwork were significantly higher than those in the control group,and there were significant differences between the two groups (P<0.05).Conclusion The flipping class combined with case teaching method in clinical paediatrics teaching is helpful to the improvement of students′ comprehensive quality and to the improvement of teaching effect.
2019 Vol. 26 (27): 175-177 [Abstract] ( 182 ) HTML (30 KB)  PDF  (0 KB)  ( 22 )
178 A case report of HIV infection with Cryptococcus neoformans bacteremia
TANG Cui-xia;LIANG Feng-qiong;GAO Yan-zhu
Cryptococcus neoformans is a deep fungus with high mortality,difficult treatment and difficult to detect.It is highly invasive,and its imaging and clinical manifestations are not typical.Patients with Cryptococcus neoformans infection have rapid onset and very high mortality.In this study,a case of abdominal pain was investigated in patients admitted to the hospital,diagnosed as human immunodeficiency virus (HIV) infection with Cryptococcus neoformans bacteremia,clinical symptoms and diagnosis and treatment processes are described in detail.With the increase in the number of patients with HIV and the widespread use of immunosuppressive agents,patients with such immunodeficiency may increase year by year,and relevant professional doctors should pay attention to the possibility of such diseases and avoid misdiagnosis and mistreatment.
2019 Vol. 26 (27): 178-180-186 [Abstract] ( 215 ) HTML (35 KB)  PDF  (0 KB)  ( 14 )
181 A case of liver failure with pulmonary fungal infection and literature review
GAO Qing-xiao;ZHANG Li-guo;LI Dong-mei;WU-Cong;DING guo-feng
Chronic liver failure is a serious liver diseases caused by multiple causes,which leads to severe disorders or decompensation of liver synthesis,detoxification,excretion and biotransformation.At last,a group of clinical symptoms mainly manifested as coagulation disorder and jaundice,hepatic encephalopathy,ascites,etc.Fungal infection mostly belongs to nosocomial infections,community infections are rare,liver failure complicated with fungal infections will lead to a sharp deterioration of the disease,the prognosis is very poor.This study retrospectively analyzed the diagnosis and treatment of a case of liver failure complicated with pulmonary fungal infection and reviewed the literature.The aim was to improve the level of diagnosis and treatment of liver failure complicated with fungal infection by clinicians,so as to improve the survival rate of patients with liver failure.
2019 Vol. 26 (27): 181-183 [Abstract] ( 220 ) HTML (31 KB)  PDF  (0 KB)  ( 14 )
184 Application effect of pain nursing in patients with common digestive system diseases
YU Yuan;LIU Shan;ZOU Ping
Objective To explore the application effect of pain nursing in patients with common digestive system diseases.Methods All of 50 patients with acute pancreatitis and cholelithiasis who received treatment in our hospital from February 2018 to February 2019 were selected as the research objects.They were divided into the control group (n=25)and study group (n=25) according to the random number table method.The control group was given routine nursing,and the study group was given pain nursing on the basis of the control group： using drugs and non-drug analgesia.The degree of pain,recovery and total satisfaction degree with nursing were compared between the two groups.Results Nunlber rating scale (NRS) score of the study group after 12,24 and 48 h of nursing were significantly lower than those before nursing,and the differences were statistically significant (P＜0.05).NRS score after 12,24 and 48 h nursing in the study group were all lower than those in the control group,and the differences were statistically significant (P＜0.05).The time of getting out of bed and hospitalization in the study group were significantly shorter than those in the control group,and the time of sleeping at night was significantly longer than that in the control group (P＜0.05).The total satisfaction degree with nursing of the study group was significantly higher than that of the control group,and the difference was statistically significant (P＜0.05).Conclusion Pain nursing quality evaluation can significantly reduce the pain of patients,and it can promote the recovery of patients and have a high degree of nursing satisfaction,it is worth to be widely promoted in clinic.
2019 Vol. 26 (27): 184-186 [Abstract] ( 227 ) HTML (33 KB)  PDF  (0 KB)  ( 14 )
187 Application of larger vein puncture and bleeding drainage in difficult puncture and bleeding drainage of internal fistula
XIAO Hui-qiong;ZENG Wei;LI Yan
Objective to explore the application effect of larger vein puncture and bleeding drainage in difficult puncture and bleeding drainage of internal fistula.Methods All of 48 patients with difficulty in puncture and bleeding drainage of internal fistula during hemodialysis treatment in our hospital from October 2017 to October 2018 were selected as the study subjects.All of them were divided into the research group and the control group by using the random number table method,with 24 cases in each group.Patients in the control group were treated with traditional method,while those in the study group were treated with larger vein puncture.The flow of hemodialysis,waiting time for hemodialysis,puncture success rate,operational miscarriage rate and the incidence of complications were compared in patients between the two groups.Results The flow of hemodialysis and puncture success rate of the study group were significantly higher than those of the control group,and the waiting time for hemodialysis was significantly shorter than that of the control group,operational miscarriage rate was significantly lower than that of the control group,with statistically significant differences (P<0.05).The total incidence of complications was 4.17% in the study group,which was significantly lower than that of the control group (29.17%),with statistically significant difference (P<0.05).Conclusion The emergency application of larger vein puncture and bleeding drainage in difficult puncture and bleeding drainage of internal fistula can shorten the waiting time for hemodialysis,reduce the operational miscarriage rate and the incidence of complications,improve the flow of hemodialysis and the success rate of puncture,facilitate the operation of medical staff and ensure the timeliness of treatment for patients with maintenance hemodialysis.
2019 Vol. 26 (27): 187-189 [Abstract] ( 178 ) HTML (31 KB)  PDF  (0 KB)  ( 17 )
190 Application effect of targeted nursing intervention in the control of nonmotor symptoms in patients with Parkinson′s disease
LU Hai-yan;MA Song-hua
Objective To explore the application effect of targeted nursing intervention in the control of non-motor symptoms in patients with Parkinson′s disease.Methods Sixty patients with Parkinson′s disease admitted to our hospital from February 2014 to June 2017 were selected and they were divided into the conventional group (n=30) and the targeted group (n=30) using simple randomization method.The routine group received routine nursing method,while the targeted group received targeted nursing intervention.The score of non-motor symptoms and daily living ability before and after nursing were compared between the two groups.Satisfaction degree with nursing staff′s service attitude,comprehensiveness,sense of responsibility and operation skills was evaluated.Results The scores of non-motor symptoms in the two groups were lower than those before treatment,and the scores of daily living ability were higher than those before nursing,and the the differences were statistically significant (P<0.05).The score of non-motor symptoms after nursing in the targeted group were lower than those in the regular group,and the score of daily living ability were higher than the conventional group,and the differences were statistically significant (P<0.05).The satisfaction scores of service attitude,comprehensiveness,sense of responsibility and operation skills for nursing staff in the targeted group were higher than those of the routine group,and the differences were statistically significant (P<0.05).Conclusion Targeted nursing intervention for patients with Parkinson′s disease can significantly reduce their non-motor symptoms,improve their daily living ability and enhance their satisfaction degree.
2019 Vol. 26 (27): 190-192 [Abstract] ( 169 ) HTML (33 KB)  PDF  (0 KB)  ( 12 )
193 Application effect of Wechat education in health education and psychological nursing of perioperative patients during laparoscopic appendectomy
YE Miao-qin
Objective To explore the application effect of Wechat education method in health education and psychological nursing for patients undergoing laparoscopic appendectomy surgery (LA).Methods A total of 100 patients with acute gangrene and perforated appendicitis treated from February 2017 to February 2019 in our hospital were selected.The subjects were divided into observation group and control group according to random number table method,50 cases in each group.The control group was adopted oral education method and the observation group was adopted Wechat education method.The awareness of health education,anxiety and depression scores before and after nursing and the average time of health education of two groups were compared.Results The awareness of health education in the observation group was higher than that of control group,with statistically difference(P<0.05).Before nursing,the anxiety and depression scores of the patients in two groups were not statistically different (P＞0.05).After nursing,the anxiety and depression scores in the observation group were lower than those of control group,with statistically difference (P<0.05);the anxiety and depression scores in the control group before and after nursing was not statistically different (P＞0.05);the anxiety and depression scores of the observation group after nursing were lower than those before nursing,the differences were statistically significant (P<0.05).The average time of education in the observation group was lower than that of control group,the difference was statistically significant (P<0.05).Conclusion The Wechat education method of patients undergoing LA can improve the health propaganda effect,improve psychological status and reduce the workload of nurses.
2019 Vol. 26 (27): 193-195-199 [Abstract] ( 183 ) HTML (33 KB)  PDF  (0 KB)  ( 13 )
196 Application effect of individualized development support assessment procedures and nursing in children with premature jaundice
ZHANG Jin-ping;YE Qi; ZHANG Cui-hua
Objective To observe the value of individualized development support assessment procedures and nursing（NIDCAP) in preterm infants with jaundice.Methods A total of 60 preterm infants with jaundice treated in our hospital from July 2017 to July 2018 were selected and divided into observation group and control group automatic generation of random numbers by computer programming,30 cases in each group.Patients in the control group were given routine nursing,while those in the observation group were additionally given NIDCAP.The bilirubin value,jaundice index,jaundice persistence and regression days,gastrointestinal function development,and child care satisfaction were compared between the two groups.Results The 7 d bilirubin value and the jaundice index were higher than those on the 1st day of birth in both groups,the 7 d bilirubin value and jaundice index of the observation group were lower than those of the control group,the duration and regression time of jaundice,the establishment of sucking and swallowing function,and the days to sufficient feeding and the improvement time of bloating were shorter in the observation group than those in the control group,and the total satisfaction was higher than that of the control group,and the differences were statistically significant (P<0.05).Conclusion For premature infants with jaundice,the application of NIDCAP can effectively control the development of jaundice,accelerate the improvement of symptoms,and promote the development of gastrointestinal function and improve the satisfaction of parents.
2019 Vol. 26 (27): 196-199 [Abstract] ( 174 ) HTML (35 KB)  PDF  (0 KB)  ( 14 )
200 Effect of comprehensive nursing model on the treatment of lumbar disc herniation after intervertebral foramen microscopy
ZHONG Mei-lian;LI Shuang-shuang;ZENG Ji-wei
Objective To analyze the effect of comprehensive nursing model on the treatment of lumbar disc herniation(LDH) after intervertebral foramen endoscopy.MethodsA total of 60 patients with LDH treated by foraminoscopy in our hospital from February 2017 to February 2019 were selected as the research objects.They were divided into control group and observation group according to random touching method,30 cases in each group.The control group was given routine nursing,while the observation group was given comprehensive post-operative nursing.The prognostic effects and incidence of complications of the two groups were compared.Results The excellent and good rate of the patients in the observation group was higher than that in the control group (P<0.05);the total incidence of complications in the observation group were lower than those in the control group (P<0.05);there was no significant difference in the psychological status between the two groups (P＞0.05);after nursing,the anxiety and depression score of the patients in the observation group were lower than those in the control group,with statistically difference (P<0.05).Conclusion Comprehensive post-operative nursing for patients with LDH treated by intervertebral foramen endoscopy can reduce complications,improve prognosis and psychological status,and has clinical application value.
2019 Vol. 26 (27): 200-202 [Abstract] ( 172 ) HTML (31 KB)  PDF  (0 KB)  ( 12 )
203 Effect of quality nursing service on prenatal education of pregnant women at high risk of pregnancy
XU Li-qin;JIANG Mei-qiong
Objective To explore the impact of quality nursing services on prenatal education in high-risk pregnant women.Methods Sixty high-risk pregnant women admitted to our hospital from October 2017 to October 2018 were selected as subjects.According to the computer grouping method,they were divided into observation group and control group,30 cases in each group.The observation group adopted high quality nursing service,the control group used routine nursing.The self-care ability measurement scale,psychological stress self-rating scale,compliance behavior,satisfaction with nursing service,satisfaction with nursing quality,pregnancy outcome,and labor process were compared between the two groups.Results The self-care ability measurement scale,compliance behavior,satisfaction with nursing service,and satisfaction with nursing quality were higher in the observation group than those of the control group,the differences were statistically significant (P<0.05).The psychological stress self-rating scale and postpartum bleeding rate,neonatal asphyxia rate,cesarean section,and premature delivery were lower than those of the control group,the differences were statistically significant (P<0.05).The first stage of labor,the second stage of labor,the third stage of labor,and the total stage of labor were shorter than those of the control group,the differences were statistically significant (P<0.05).Conclusion The implementation of high-quality nursing service intervention for high-risk pregnant women is effective,which can improve the satisfaction of pregnant women and compliance with medical behavior,enhance the self-care ability of pregnant women,reduce the feelings of inner anxiety and anxiety,and thus effectively improve the pregnancy outcome.
2019 Vol. 26 (27): 203-205-207 [Abstract] ( 218 ) HTML (34 KB)  PDF  (0 KB)  ( 19 )
206 Application effect of respiratory rehabilitation nursing in postoperative rehabilitation of patients with severe thoracic surgery
CAO Yu-dan;HUANG Li
Objective To explore the application effect of respiratory rehabilitation nursing in postoperative rehabilitation of patients with severe thoracic surgery.Methods A total of 100 patients with severe thoracic surgery who underwent surgical treatment in our hospital from January to December 2018 were enrolled in the study.They were divided into control group and observation group according to the principle of randomized comparison,with 50 cases in each group.The patients in the control group received routine nursing,while those in the observation group received respiratory rehabilitation nursing on the basis of the control group.The incidence of surgery related complications,quality of life (physical health [PF],physical role function [RP],body pain [BP],psychological function [MH],emotional role function [RE],vitality [VT],social function [SF],general health [GH]) score before and after surgery (2 weeks after surgery),lung function indexes (pulmonary capacity [VC],tidal volume [TV],forced vital capacity in the first second [FEV1],forced vital capacity [FVC],FEV1/FVC) and blood gas analysis indicators (arterial blood oxygen partial pressure [PaO2],arterial carbon dioxide partial pressure [PaCO2]) 2 weeks after surgery were compared between the two groups.Results The TV,VC,FVC,FEV1,FEV1/FVC and PaO2in the observation group were higher than those in the control group at 2 weeks after surgery,and the differences were statistically significant (P<0.05).There was no significant difference in PaCO2 between the two groups (P>0.05).There was no significant difference in the quality of life score between the two groups before surgery (P>0.05).The quality of life scores of the two groups at 2 weeks after surgery were higher than those before surgery,and the differences were statistically significant (P<0.05).The quality of life scores in the observation group at 2 weeks after surgery were higher than those in the control group,and the differences were statistically significant (P<0.05).The total incidence rate of surgical related complications in the observation group was lower than that in the control group,and the difference was statistically significant (P<0.05).Conclusion Respiratory rehabilitation nursing can promote the recovery of postoperative pulmonary function in patients with severe thoracic surgery,improve the life quality and reduce the incidence rate of complications,which is worthy of clinical recommendation.
2019 Vol. 26 (27): 206-209 [Abstract] ( 201 ) HTML (37 KB)  PDF  (0 KB)  ( 20 )
210 Application effect of psychological nursing combined with routine nursing in patients with early diabetic nephropathy
DIAO Yan;ZHAO Jin-zhong;CHEN Shao-hua
Objective To study the effect of psychological nursing combined with routine nursing in the elderly patients with early diabetic nephropathy(DN).Methods A total of 230 patients with early DN admitted to our hospital from October 2016 to October 2017 were selected as the research objects.They were divided into control group and research group according to the random number table method,115 cases in each group.The control group was given routine nursing methods,and the research group was given psychological nursing besides routine nursing.The glycosylated hemoglobin (HbA1c),fasting blood glucose (FPG),postprandial 2 h blood glucose (2 h FPG),insulin resistance index(HOMA-IR)，and nursing satisfaction were compared between the two groups.Results After treatment,the levels of HBA1c,FPG,2 h FPG,HOMA-IR in the two groups were significantly lower than those before treatment (P<0.05),the indexes in the research group were significantly lower than those in the control group (P<0.05),and the nursing total satisfaction of the research group was significantly higher than that of the control group (P<0.05).Conclusion Choosing psychological nursing in early DN patients is more effective and can be more helpful to the rehabilitation of patients.
2019 Vol. 26 (27): 210-212 [Abstract] ( 184 ) HTML (31 KB)  PDF  (0 KB)  ( 17 )
213 Application study on psychological characteristics and intervention strategies of high risk HPV infection patients
HUANG Wei;ZHU Xiao-li;MA Xi;FENG Li-xia;ZHU Zhi-yu;YANG Shan;ZHOU Li
Objective To explore the psychological characteristics and intervention strategies of high-risk patients with human papillomavirus （HPV） infection.MethodsEighty high risk HPV infected patients admitted to our hospital from June 2017 to December 2018 were enrolled in the study.They were randomly divided into group A (40 cases) and group B (40 cases).Group A was used routine nursing,group B was used routine nursing plus psychological cognitive behavioral therapy,the psychological abnormality rate,self-rating anxiety scale (SAS) score,treatment compliance,psatisfaction,Pittsburgh sleep quality scale (PSQI) score,medical coping style scale (MCMQ) score were compared between two groups.Results The abnormal rate of psychological condition in 80 patients was 90.00%,of which anxiety was 40.00%,interpersonal sensitivity 20.00%,somatization 20.00%,obsessive-compulsive symptom 10.00%.After nursing,the SAS score of group B was (32.26±6.32) points,lower than that of group A for (44.57±4.29) points,the difference was statistically significant (P<0.05).The total therapeutic compliance and nursing total satisfaction of group B were significantly higher than those of group A (P<0.05).The PSQI score of group B after nursing was (6.13±1.7) points,lower than that of group A for (11.3±1.2) points,the difference was statistically significant (P<0.05).The face score of group B was higher than that of group A,and the scores of avoidance and yield were lower than those of group A (P<0.05).Conclusion The high risk patients with HPV infection often have bad psychological emotions,such as anxiety,suspicion,shame and so on.Psychological nursing can effectively improve the quality of life of patients and improve their bad psychological mood from these points of view.Improve nursing compliance and satisfaction.
2019 Vol. 26 (27): 213-216 [Abstract] ( 179 ) HTML (40 KB)  PDF  (0 KB)  ( 16 )
217 Application effect of psychological nursing combined with exercise therapy in gestational diabetes mellitus
WU Ren-qing
Objective To explore the application effect of psychological nursing combined with exercise therapy in gestational diabetes mellitus (GDM).Methods A total of 86 cases of GDM parturients treated in our hospital from April 2016 to April 2018 were selected and divided into control group and observation group according to the list of mathematical random number,43 cases in each group.The control group was given routine nursing intervention during pregnancy,while the observation group was given exercise therapy combined with psychological nursing intervention.The nursing total satisfaction,maternal and infant adverse events,the disappearance time of GDM symptoms and the total time of intervention plan implementation,blood sugar levels before and after nursing were compared between the two groups.Results The nursing total satisfaction of patients in the observation group was higher than that of the control group,with statistically difference (P<0.05);the incidence of adverse events was lower than that of the control group,with statistically difference (P<0.05);the disappearance time of GDM symptoms and the total implementation time of intervention plan were shorter than that of the control group,with statistically difference (P<0.05);the blood sugar level after nursing was lower than those of the control group,with statistically difference (P<0.05).Conclusion Motion therapy combined with psychological nursing intervention can reduce adverse events of mother and infant,control symptoms and blood sugar level in a short time,shorten treatment time and improve patients′satisfaction with nursing nursing during the treatment of GDM.
2019 Vol. 26 (27): 217-219 [Abstract] ( 204 ) HTML (30 KB)  PDF  (0 KB)  ( 15 )
220 Effect of anesthesia recovery nursing in operating room on restlessness during recovery period of hysterectomy
TAN Li-juan
Objective To investigate the effect of anesthesia recovery nursing in operating room on restlessness during recovery period （EA） of hysterectomy.MethodsSeventy patients undergoing hysterectomy admitted to our hospital from January 2016 to December 2018 were enrolled in this study.They were divided into control group and observation group according to random sampling method,35 cases in each group.Routine nursing was given to the control group and anesthesia recovery nursing was given to the observation group.The degree of agitation,heart rate and blood pressure were compared between the two groups.Nursing satisfaction was recorded.Results The incidence of EA in the observation group was 25.71%,which was significantly lower than that in the control group (48.57%) （P<0.05）.The heart rate,diastolic blood pressure and systolic blood pressure in the observation group were (76.28±10.55) times/min,(85.32±10.42) mmHg and (135.68±12.57) mmHg,were lower than the control group for (87.11±8.44) times/min,(94.22±11.28) mmHg,and (148.28±13.38) mmHg,（P<0.05）;the total nursing satisfaction of the observation group was 94.29%,higher than 77.14% of the control group （P<0.05）.Conclusion Targeted nursing intervention has a good effect on reducing the incidence of EA general anesthesia in patients with hysterectomy,which helps patients to recover their disease and reduce the occurrence of accidents,at the same time,improve nursing satisfaction.
2019 Vol. 26 (27): 220-222 [Abstract] ( 167 ) HTML (32 KB)  PDF  (0 KB)  ( 10 )
223 Practical effect of self-management model in postoperative rehabilitation of patients with lumbar disc herniation
LIU Yuan-fei;WEI Jun;YANG Jun;ZHANG Xin-hong;LIU Fen-fen
Objective To explore the practical effect of self-management model in postoperative rehabilitation of lumbar disc herniation (LDH).Methods From January to December of 2017,200 patients of LDH treated with CT-guided percutaneous endoscopic resection of nucleus pulposus were selected.The patients were divided into observation group and control group according to random number table method,100 cases in each group.The control group adopted the conventional education model,and the observation group implemented self-management model on the basis of the control group.Visual analogue scale (VAS) score,self-management assessment scale,quality of life assessment (QOL)scale and compliance rate of disease-related knowledge were compared in the two groups.Results After intervention by self-management model,VAS and QOL score in the observation group were lower than those in the control group,and the self-managerment assessment scale scores and compliance rate of disease-related knowledge were higher than those in the control group,with statistically differences (P<0.05).Conclusion The effect of self-management model in postoperative rehabilitation of LDH is satisfactory.
2019 Vol. 26 (27): 223-225 [Abstract] ( 189 ) HTML (32 KB)  PDF  (0 KB)  ( 18 )
226 Effect of natural drying method of umbilical cord in nursing of newborn umbilical cord healing
YANG Cui;CAO Zhen
Objective To explore the effect of natural drying of umbilical cord in neonatal umbilical cord nursing.Methods A total of 400 neonates in our hospital from June 2017 to December 2018 were selected as the study subjects,and all of them were divided into control group and the experimental group according to random number table method,200 cases in each group.Routine umbilical care was taken in the control group,and natural drying method was taken in the experimental group,the healing of umbilical cord was compared between the two groups.Results The time of umbilical cord shedding and complete umbilical cord repair in the experimental group were shorter than those in the control group,the differences were significant (P<0.05).The incidence of neonatal umbilical hemorrhage in the experimental group was significantly lower than that in the control group (P<0.05),and there was no significant difference in the incidence of neonatal omphalitis and umbilical granuloma (P＞0.05).ConclusionNatural drying method of umbilical cord in neonatal umbilical cord care can significantly shorten the umbilical cord shedding time,reduce umbilical complications,and promote early umbilical cord healing.
2019 Vol. 26 (27): 226-228 [Abstract] ( 167 ) HTML (31 KB)  PDF  (0 KB)  ( 13 )
229 Application of extra-hospital continuous nursing in patients with hypertensive cerebral hemorrhage
HE Zi-hong
Objective To explore the effect of extended nursing outside hospital in patients with hypertensive intracerebral hemorrhage (HCH).Methods A total of 120 patients with HCH admitted to our hospital from January to December 2018 were selected as the research objects.According to whether they received continuing nursing after discharge,they were divided into observation group (60 cases) and control group (60 cases).The control group received routine discharge guidance and regular telephone follow-up.The observation group carried out continuing nursing after discharge.The changes of blood pressure control,life ability,self-care ability and quality of life after discharge were compared between the two groups.Results The levels of systolic blood pressure (SBP) and diastolic blood pressure(DBP) in the observation group were significantly lower than those in the control group at 3 months after discharge (P<0.05);the scores of activities of daily living (ADL),exercise of self-care agency (ESCA) and generic quality of live inventory 74 (GQOLI-74) in the observation group were significantly higher than those in the control group at 3 months after discharge (P<0.05).Conclusion Extra-hospital continuous nursing can improve the blood pressure control effect of patients with HCH after discharge,improve their life ability,self-care ability and quality of life,which is worthy of clinical recommendation.
2019 Vol. 26 (27): 229-231 [Abstract] ( 196 ) HTML (33 KB)  PDF  (0 KB)  ( 14 )
232 Application research of pipeline risk assessment system in safety management of Thoracic Surgery
LI Wei-na
Objective To investigate the application of pipeline risk assessment system in the safety management of thoracic surgery.Methods Eighty patients with thoracic surgical bandage who admitted to our hospital from January 2018 to January 2019 were selected as the subjects.They were divided into control group and study group according to the random number table method,40 cases in each group.The control group used conventional pipeline safety management intervention,and the study group jointly applied the pipeline risk assessment system on this basic.The occurrence of pipeline safety problems,nursing staff work efficiency,and clinical nursing total satisfaction were compared between two groups.Results The incidence of pipeline safety problems in the study group (7.50%) was lower than that in the control group (25.00%),and the difference was statistically significant (P<0.05).The shift time of nurses in the study group ([5.80±1.25]s) was shorter than that in the control group ([9.95±1.35]s),and the difference was statistically significant (P<0.05).The pipeline identification time of the study group ([1.85±0.50]s) was shorter than that of the control group ([4.35±0.85]s),and the difference was statistically significant (P<0.05).The clinical total nursing satisfaction of the study group (82.50%) was higher than that of the control group (25.00%),and the difference was statistically significant (P<0.05).Conclusion The application of pipeline risk assessment in the safety management of thoracic surgery pipelines system interventions can significantly reduce the occurrence of pipeline safety problems,which can significantly improve the efficiency of nursing staff and clinical nursing satisfaction.
2019 Vol. 26 (27): 232-234 [Abstract] ( 159 ) HTML (31 KB)  PDF  (0 KB)  ( 14 )
235 Application effect of comprehensive elderly assessment combined with unaccompanied nursing in elderly patients with coronary heart disease
DING Rui-ying
Objective To explore the application effect of comprehensive elderly assessment （CGA） combined with unaccompanied nursing in elderly patients with coronary heart disease (CHD).Methods A total of 112 elderly patients with unaccompanied CHD admitted to our hospital from April 2016 to May 2018 were selected and randomly divided into observation group (56 cases) and control group (56 cases).The control group was given routine nursing,while the observation group was given CGA combined with unaccompanied nursing.The nursing total satisfaction,incidence of cardiovascular adverse events and life quality scores before and after nursing were compared between the two groups.Results The total incidence of adverse cardiovascular events and quality of life scores in the observation group were significantly lower than those in the control group (P<0.05).Nursing total satisfaction in the observation group was higher than that in the control group,and the difference was statistically significant (P<0.05).Conclusion CGA combined with unaccompanied nursing can significantly reduce the incidence of cardiovascular adverse events in elderly patients with CHD,effectively improve the quality of life of patients and satisfaction with nursing,which is worthy of clinical promotion.
2019 Vol. 26 (27): 235-237 [Abstract] ( 191 ) HTML (33 KB)  PDF  (0 KB)  ( 14 )
238 Influence of hospital-family continuing nursing on rehabilitation effect and psychological status of patients with schizophrenia after discharge
HUANG Xiao-hua;ZHANG Wei-juan;XIA Zhi-min;ZHAO Juan
Objective To explore the influence of hospital-family continuing nursing on rehabilitation effect and psychological status of patients with schizophrenia after discharge.Methods All of 94 patients with schizophrenia treated in our hospital from January 2017 to June 2018 were selected as study objects and they were divided into the two groups,and each group had 47 cases.The control group was given routine discharge nursing,while the research group was given hospital-family continuing nursing.The score of compliance behavior,self-rating anxiety scale (SAS),selfrating depression scale (SDS) and inpatient psychiatric rehabilitation outcome scale (IPROS) were compared in patients between the two groups.Results The score of compliance behavior in the study group was significantly higher than that in the control group (P<0.05).There was no significant difference in SAS score,SDS score and IPROS score in patients between the two groups before intervention (P>0.05).After intervention,the SAS,SDS and IPROS score of the study group were lower than those of the control group (P<0.05).Conclusion After discharge,schizophrenic patients received hospital-family continuing nursing have good compliance behavior,obvious rehabilitation effect,and good psychological improvement.
2019 Vol. 26 (27): 238-240 [Abstract] ( 160 ) HTML (35 KB)  PDF  (0 KB)  ( 16 )
241 Application effect of clustering nursing intervention after interventional therapy for massive hemoptysis of pulmonary tuberculosis
LIU Ji-hua;YANG Shui-xiu;TAN Cai-ping
Objective To explore the application effect of clustering nursing intervention after interventional therapy for massive hemoptysis of pulmonary tuberculosis.Methods A total of 60 patients receiving nterventional therapy for massive hemoptysis of pulmonary tuberculosis in our hospital from May 2016 to May 2018 were selected and divided into the observation group and the control group according to their admission time,30 cases in each group.Patients in the observation group were given clustering nursing intervention,and patients in the control group were given routine nursing.The nursing effects were compared between the two groups.Results There was no significant difference in psychological status score between the two groups before intervention (P＞0.05).After intervention,the scores of psychological status in the observation group were significantly improved,and the scores in the observation group were lower than those in the control group (P＜0.05).The quality of life score of the observation group was higher than that of the control group (P＜0.05).Conclusion The application effect of clustering nursing intervention after interventional therapy for massive hemoptysis of pulmonary tuberculosis is significant,which can effectively relieve the patients mental tension and improve their quality of life.
2019 Vol. 26 (27): 241-243 [Abstract] ( 165 ) HTML (31 KB)  PDF  (0 KB)  ( 18 )
244 Influence of continuous nursing on postoperative self-care ability and body rehabilitation of patients with benign prostatic hyperplasia
LIU Li-fang
Objective To explore the influence of continuous nursing nursing on postoperative self-care ability and body rehabilitation of patients with benign prostatic hyperplasia (BPH).Methods A total of 83 cases of patients who accepted BPH in urology department of our hospital from January to December 2018 were selected as the research objects,and they were divided into the experimental group (n=42) and the control group (n=41) according to random number table method.The experimental group was given continuing nursing through WeChat and telephone,the control group was given discharge instruction.The quality of life,prostate symptoms,self-care ability and health behavior at 3 months after discharge of the two groups were compared.Results The score of quality of life (QOL) and international prostate symptom score (IPSS) of the patients in the experimental group were significantly lower than those in the control group (P＜0.05).The scores of self-care ability and healthy behavior in the experimental group were significantly higher than those in the control group (P＜0.05).Conclusion Continuous nursing can improve postoperative quality of life and self-care ability of patients with BPH,improve prostate symptoms,and regulate patients′ self-health behaviors.
2019 Vol. 26 (27): 244-246 [Abstract] ( 196 ) HTML (33 KB)  PDF  (0 KB)  ( 16 )
247 Application effect of one-handed protection of perineal delivery in natural delivery of primipara
ZHANG Min;WANG Wen-hua;HE Li-yan
Objective To study the effect of one-handed perineal delivery method in natural delivery of primipara.Methods The clinical data of 200 primipara who gave birth naturally in our hospital from June 2016 to May 2018 were retrospectively analyzed.They were divided into two groups according to the different ways of delivery.100 primipara who received traditional perineal protection measures from June 2016 to May 2017 were taken as control group,and 100 primipara who received one-handed perineal protection method from June 2017 to May 2018 were taken as observation group.The amount of vaginal bleeding,the time of delivery,the rate of lateral perineal excision,the degree of perineal edema and pain,the degree of perineal laceration,the condition of neonates,satisfaction and hospitalization time were compared between the two groups.Results There was no significant difference in the amount of vaginal bleeding between the two groups (P>0.05).The second stage of labor in the observation group was longer than that in the control group,and the hospital stay was shorter than that in the control group,the differences were statistically significant (P<0.05).The incidence of perineal cut and postpartum perineal edema in the observation group were lower than those in the control group,the differences were statistically significant (P<0.05).The degree of perineal laceration and perineal pain in the observation group were better than those in the control group,with statistically significant (P<0.05).The Apgar score of the newborns in the observation group was higher than that of the control group,the difference was statistically significant (P<0.05).The total satisfaction of the primipara in the observation group was higher than that of the control group,and the difference was statistically significant (P<0.05).Conclusion Single-handed perineal with protection during natural delivery of primipara is helpful to reduce the rate of lateral perineal incision,the degree of perineal laceration and the degree of postpartum perineal pain.The effect is satisfactory and the clinical application value is high.
2019 Vol. 26 (27): 247-249 [Abstract] ( 188 ) HTML (34 KB)  PDF  (0 KB)  ( 16 )
250 Influence of clinical nursing pathway combined with responsibility system nursing on post-operative rehabilitation of patients undergoing tubal pregnancy surgery
XU Qing-qing
Objective To analyze the influence of clinical nursing pathway combined with responsibility system nursing on post-operative rehabilitation of patients undergoing tubal pregnancy surgery.Methods Altogether 50 patients with tubal pregnancy treated by operation in our hospital from August 2016 to December 2018 were selected and randomly divided into the experiment group and the control group,with 25 cases in each group.The experiment group was given clinical nursing pathway combined with responsibility system nursing,while the control group was given routine nursing.The post-operative rehabilitation and patients′ satisfaction with nursing were evaluated.Results The operation time,hospitalization time and anal exhaust time of the experiment group were shorter than those of the control group,the amount of bleeding during operation of the experiment group was less than that of the control group,the incidence of ectopic pregnancy of the experiment group was lower than that of the control group,and the incidence of intrauterine pregnancy of the experiment group was higher than that of the control group,with significant difference (P＜0.05).There was no statistically significant difference in the incidence of side effects between the two groups (P＞0.05).The patients′nursing total satisfaction of the experiment group was higher than that of the control group,the difference was statistically significant (P＜0.05).Conclusion The application of clinical nursing pathway combined with responsibility system nursing in the treatment of patients with tubal pregnancy surgery is conducive to the rehabilitation of patients after operation,and can improves the patients′ satisfaction with nursing work,which is worthy of clinical promotion and application.
2019 Vol. 26 (27): 250-252 [Abstract] ( 169 ) HTML (31 KB)  PDF  (0 KB)  ( 14 )
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